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Methylation and MTHFR: Does your practitioner really know how to address these? Brought to you by: The Center for Bio Individualized Medicine™ Finding Answers Through Genetics and Integrative Medicine Dr. Jess P. Armine Shawn Bean, B.S. [email protected] (610) 449 9716

Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

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Page 1: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Methylation and MTHFR: Does your practitioner really know how to

address these?

Brought to you by:

The Center for Bio Individualized Medicine™ Finding Answers Through Genetics and Integrative Medicine

Dr. Jess P. Armine

Shawn Bean, B.S.

[email protected]

(610) 449 9716

Page 2: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Acknowledgements & Disclaimer

The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and Sterling’s App.

The E-Book “MTHFR Basics” by Benjamin Lynch, ND available on Amazon.com

Some writings by Amy Yasko, PhD

Other references will be made on specific pages

Copies of advertisements are from the public domain and not private, proprietary information. No individual names have been identified.

All patient identifying data has been removed for privacy reasons.

Page 3: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

MTHFR & METHYLATION…IT’S SIMPLE, RIGHT?

And So Very Important….But What is MTHFR and how important is it, Really?

Page 4: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

© Dr. Jess Armine 2015

Here’s Where it All Began…MTHFRWhat is it?

Quite simply MTHFR is a gene

Genes encode (creates) enzymes

Enzymes (among other things) make our body’s biochemistry work

MTHFR is known by names like “The Mother Father” Gene or other unsavory names, MTHFR means Methylenetetrahydrofolate Reductase

Why do people pay sooooo much attention to MTHFR????

Page 5: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

© Dr. Jess Armine 2015

What is MTHFR’s Function?

MTHFR changes dietary folate and folic acid (useless in and of itself) into forms that the body can use, like methylfolate

Green, leafy vegetables, folinic acid and methylfolate are the best source of active folates.

From MTHFR Basics, Dr. Ben Lynch

Page 6: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

© Dr. Jess Armine 2015

Folate and MethylationJust Part of the Big Picture

From Dr. Yasko

MTHFS Dietary Folate

This Circle is the Methylation Pathway

Page 7: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

A Broader ViewAmy Yasko, PhD

This Circle is the Methylation Pathway

Page 8: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

The Big Kahuna!From Dr. Ben Lynch

In the Brackets is the Methylation Pathway

Page 9: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

That Little Point is the Methylation PathwayRoughly

Page 10: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Sorta Like This

Page 11: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Why Did I Explain MTHFR & Methylation Thus?

To give you a sense of what this pathway does and its relative importance

To give you perspective of where methylation fits in the entirety of your biochemical pathways

To empower you with the knowledge that MTHFR & Methylation are NOT the alpha and omega of your health problems

To give a basis for the remainder of this podcast

Page 12: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

How Should The Genes Be Used?

Bio-Individualized Medicine

Page 13: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Essentially

You Can’t Just Treat the Genes (it’s an

impossibility)

Treat The Body Using the Genes as Guideposts

In Other Words, You MUST Treat What Caused the SNPs to Express Because…Genetics Loads the Gun but Environment Pulls The Trigger

Page 14: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

WHAT IS BEING PRESENTED TO YOU?

But….this takes time and effort. A simplified approach was demanded….is it good or bad? It depends….

Page 15: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Computer Programs That “Encourage” Supplements Based on SNPS

Page 16: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

The “Client’s Copy” of yet another

Page 17: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and
Page 18: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Really? DAO is known to metabolize histamine

May?

Page 19: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and
Page 20: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Why a “Limited View”

MAO A

COMT

GAD

DAO

MTHFR 1298C

MTHFR C677T

DHFR

NOS

ACE

ADD

AGT

VDR

G6PD

FUT

DHFR

CBS

MTRR

GIF

MTR

TCN

PEMT

BHMT

PEMT

SOD

GSTM1

GSTP

SHMT

CTH

CBS

FOLR

44 SNPS (counting variations)Vs.

825 SNPS (counting variations in Sterling’s App)

Page 21: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Create the Need……

Fulfill the need

Page 22: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

The Practitioner’s Copy of the same program contains the exact products that will “treat the

snps”

No Fuss, No Muss, No Thinking….Just Profit!

Page 23: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Product

Page 24: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and
Page 25: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and
Page 26: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

EVEN VENERABLE ESTABLISHED COMPANIES

I’m Shocked!

Page 27: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Let’s give you a “practitioner-exclusive website application”, just look at 8 SNPs and target products.

Page 28: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

EDUCATING THE HEALTH CARE PRACTITIONER

What are the docs learning?

Page 29: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

What it Takes…To Practice “Methylation”?

I Use The Term Loosely

In other words, what does it take to be able to care for complex cases with the expertise of Shawn Bean, Dr. Jess Armine, Dr. Ben Lynch, Dr. Amy Yasko, Sterling Hill, Cynthia Smith, etc. ?

Research

Experience

Collaboration

Willingness to think outside the box

Ability and willingness to take the proper time and effort for each case.

There Are No Shortcuts!!!But…..

Page 30: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Quickie Weekend Courses Abound

Is This Learning to Heal or A Way To Increase Your Income?

Page 31: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Your Patient’s ALL Have Methylation Problems

All??? The Whole World??? Everyone has Methylation Problems?

And for $1000, you too can partake in this wonderful method of healing….

Page 32: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

This one is tied to one of the programs above.

Everyone is jumping on the “Methylation“ Bandwagon

The question you should be asking at this point is…

Page 33: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Did My Doctor Take One of These Quickie Educational Courses?How Do I Know?

I Guess You Could Ask, But, Just in Case…

Hints: All of a sudden, your HCP

starts talking Methylation coupled with:

Using a computer program and/or using marketing material from a vitamin company or practice management group.

Puts in place a brand new set of vitamins…and the biggest indicator

You walk out of the office with a shopping bag full of product

Page 34: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

How SHOULD my HCP act?

What should you expect when your HCP says they “do” methylation?

Page 35: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Use Genetics in Its Proper Place

Methylation Is but a small part of your overall physiologyYou need to treat the physiology….NOT the genes!!!

Page 36: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

This is What a HCP Should Be Doing

Your HCP should be willing and able to identify and treat not only the root cause(s) of dysfunction but also attend to the "downstream" effect. That is, fixing whatever the primary causative agent did to the body.

As a minimum, the practitioner should have expertise in Neuro-Endo-Immunology

Epigenetics/nutrigenomics

Acquired (secondary) mitochondrial dysfunction

Cell wall integrity

AND be willing and able to take the proper time and effort to assess each component’s contribution to the presenting complaints. AKA, getting to the bottom of what is ailing the body.

(c) Dr. Jess P. Armine2015

Page 37: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

In Other Words

To Heal a Fish Make the Water Healthy

Page 38: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Shawn Bean and I created Bio-Individualized Medicine to teach HCPs to place genetics and integrative medicine in its proper perspective for YOUR benefit.

(To forestall arguments: evidencing this is the fact that, although offered, we don’t have our own product line. We consult and teach and do so without the questionable stimulus of our own products)

Page 39: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Health Care Practitioners

How Do I Choose?

Page 40: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Good Question

There are many referral lists out there, but one has to ask, “How did they qualify for the list?”

Did they take a course with/without a test?

Did they solely attend an online or weekend seminar/webinar

Is there no rhyme or reason?

More:• Did anyone work with these practitioners and

make sure they know what they are talking about

Page 41: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

AND WE ARE PROUD OF OUR PRACTITIONERS!

We Have a Referral List

Page 42: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Go to: Click:

www.methylationsupport.com Recommended Methylation Practitioners

These Practitioners have met the following requirements:

• They have attended (physically or virtually) the MABIM course in January 2015.

• AND/OR

• Have taken 2 of 3 methylation courses from Dr. Ben Lynch

• AND/OR

• Have completed FDN training

• AND/OR

• Have completed the entire webinar series from The Center for Bio-Individualized Medicine with a score of 90 or above (COMING SOON)

• AND have spent sufficient time mentoring with Shawn Bean and Dr. Jess Armine and have demonstrated competency in Bio-Individualized Medicine. (We are the ONLY people doing this!)

OUR PRACTITIONER LIST

Page 43: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

Our Treatment @ CBIM

Ameliorating biochemical malfunctions utilizing:

History and appropriate testing to discover the root causes and downstream effects of each individual

Developing Individualized Treatment Plans *that may include:

Intravenous Nutritional Therapy (High dose Vitamin C, NAD, Amino Acids, etc)

Targeted Amino Acid Therapy, NeuroAdaptive Amino Acid Therapy, Natural Hormonal Balancing

Neurotransmitter balancing, to balance mood naturally GI repair to downregulate the immune response. Much More…

(c) Dr. Jess P. Armine2015

* Protocol is a 4 letter word in our office…we practice Individualized Medicine

Page 44: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

(c) Dr. Jess P. Armine2015

How to Contact Us

Dr. Armine can be obtained inside and outside the USA by:

E-mail: [email protected]

Fill in contact form at www.methylationsupport.com

Phone: 610 449 9716

Shawn Bean:

E-mail: [email protected]

Fill in contact form at www.methylationsupport.com

Phone: 610 449 9716

Page 45: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

In Conclusion, What have we learned?

MTHFR and Methylation is important but, in reality, is a small fish in a big ocean.

Treating MTHFR and Methylation, in and of itself, is an impossibility (you can’t change the snps but you can affect their expression).

As such, products geared toward treating the snps are of questionable benefit.

Quickie weekend course, short webinars can only introduce these concepts but it takes much more to reach a level of expertise

Computer programs that base nutritional recommendations on the snps are working from an inaccurate and dangerous premise

When choosing a HCP, be discerning as to their actual expertise in this important area of health care.

But, Most of all…

Page 46: Methylation and MTHFR...Acknowledgements & Disclaimer The research for this podcast was taken from the writings of MTHFR pioneer, Sterling Hill Erdei, creator of MTHFRsupport.com and

If you want to get well…

Treat the water in order to heal the fish…