M A S C C • S u p p o r t i v e C a r e m a k e s e x c e l l e n t c a n c e r c a r e p o s s i b l e

Multinational Association of Supportive Care in Cancer • www.mascc.org

NEWSMessage from the Editorial TeamMessage from Anna Ugalde and Anna Boltong

Welcome to the July 2013 edition of the MASCC Society News. We hope you enjoyed the MASCC Congress in Berlin and we look forward to bringing you all the news from the meeting in our upcoming editions. Over these next few editions we’ll also be profiling MASCC’s study groups. In this month’s issue we feature the Palliative Care Study Group. We also have some information about Touch Medical Media, which has a content sharing agreement with MASCC we think you will find it exciting to know more about. We continue to introduce you to some new MASCC members and highlight some of the journal articles published recently by our MASCC colleagues. As always, you can keep us updated with any MASCC member news or events, including research or clinical achievements. We can be contacted at anna.ugalde@svhm.org.au or anna.boltong@petermac.org.

Anna & Anna

Profile of the Palliative Care Study GroupThe Palliative Care Study Group is the largest MASCC Study Group, with 238 members. The Palliative Care Study Group is chaired by Mellar Davis and the group is co-chaired by David Makumi. This study group aims to advance palliative-care practices within supportive oncology and to contribute to the development of guidelines. The Palliative Care Study Group recently completed a systematic review on the treatment of nausea and vomiting in advanced cancer, which is currently in press in the Journal of Pain and Symptom Management. In addition, the group has just completed a survey in conjunction with the European Society for Medical Oncology (www.esmo.org) and European Association for Palliative Care (http://www.eapcnet.eu) on international integration of palliative care into oncology and the structure of palliative care programs internationally. At the annual MASCC meeting in Berlin in June, the palliative care study group presented results on its international survey and the development of palliative care services. In the future, this group may look into identifying and publishing palliative care indicators that can be used to monitor and improve end-of-life experiences of cancer patients.

Meet a new MASCC Member! - Aline Rocha LimaI’m a medical oncologist and I work and live in Santo Andre nearby Sao Paulo, Brazil. I work in a private practice and in a Medical Residency program. I’m involved in supportive care taking care of my own patients from the beginning until the end of life. I try to integrate oncology, palliative and supportive assistance for all my patients. While I was studying and came across some articles identified on the MASCC website, I was encouraged

and decided to join MASCC. Another reason is to help my institution become stronger and ensure best practices in supportive cancer care for our patients.

Palliative Care Study Group Leader, Mellar Davis

M A S C C • S u p p o r t i v e C a r e m a k e s e x c e l l e n t c a n c e r c a r e p o s s i b l e

Multinational Association of Supportive Care in Cancer • www.mascc.org

Congratulations to Anna Boltong!Completion of milestones is always something to celebrate in these newsletters. This month it is wonderful news to announce that Anna Boltong (Pictured) has submitted her doctoral dissertation at the University of Melbourne, Australia. Her research has helped to characterise the influence of chemotherapy on taste function across the treatment trajectory in order to support best possible management of taste problems experienced by so many of our cancer patients. This research was a truly interdisciplinary piece of work, shaped by the input of medical oncologists, oncology nurses and sensory scientists as well as via Anna’s own professional background in clinical dietetics. Research findings will be used to guide the development of more specific pre-chemotherapy education material for patients.

Publications arising from Anna’s PhD include:

Boltong, A., Keast, R., & Aranda, S. (2012) Experiences and consequences of altered taste, flavour and food hedonics during chemotherapy treatment. Supportive Care in Cancer, 20(11): 2765-2774

Boltong, A., & Keast, R. (2012) The influence of chemotherapy on basic taste perception and food hedonics: A systematic review, Cancer Treatment Reviews, 38(2): 152-63

Boltong, A., Keast, R., & Aranda, S. (2011) Talking about taste: How do oncology clinicians discuss and document taste problems? Cancer Forum, 35(2): 81-87

If you wish to contact Anna about her work, you can email her at anna.boltong@petermac.org

Congratulations Anna!

Meet a new MASCC Member! - Regina de MendonçaI am dentist who has worked at the Centro Infantil Boldrini, an oncology and hematology pediatric hospital in Campinas, Brazil, since January 2001. I have an MsC in Oncology and PhD in child and adolescent health. I am involved in supportive care via our Department of Dentistry, which enables all patients to receive dental treatment when needed. Our goal is to prevent or reduce complications related to cancer and its treatment. I work in the dental care of pediatric patients with cancer and chronic blood disorders and conduct research on oral health in this population. For many years I have followed the activities promoted by MASCC / ISOO including study groups, publications and meetings. The quality of this work motivated me to become a MASCC member.

We wish to congratulate Dr de Mendonca for her recent publication in Supportive Care in Cancer:

de Mendonça, RMH., de Araújo, M., Lecy, C.E., Morari, J., Silva, RA., Yunes, JA., Brandalise, SR. (2012) Prospective evaluation of HSV, Candida spp., and oral bacteria on the severity of oral mucositis in pediatric acute lymphoblastic leukemia. Supportive Care in Cancer, 20(5), 1101-1107.

Please know we are also interested in knowing about all of the important milestones achieved by our MASCC members. Please tell us so that we can make everyone aware of the wonderful accomplishments that testify to the strength, ideas and enthusiasm of the people working in supportive cancer care.

M A S C C • S u p p o r t i v e C a r e m a k e s e x c e l l e n t c a n c e r c a r e p o s s i b l e

Multinational Association of Supportive Care in Cancer • www.mascc.org

Content Sharing Agreement between MASCC and Touch Medical Media

This month we profile Touch Medical Media in an interview by Barney Kent, managing director. In 2013, a content sharing agreement has been agreed upon between Touch Medical Media and MASCC.

Who are Touch Medical Media?Touch Medical Media (TMM) provide independent, cutting-edge peer-reviewed content from world-renowned physicians, designed to lead the debate on health and to engage, inform, and support physicians in improving patient outcomes globally. TMM provides an international platform for peer-reviewed content from industry-leading journals alongside other carefully selected sources and aims to support physicians, clinicians and leading industry professionals in continuously developing their knowledge, effectiveness and productivity within the field of oncology.

TMM’s portfolio of peer-reviewed journals, European Oncology & Haematology and Oncology & Hematology Review (US) include concise review articles, which are designed to keep busy physicians up-to-date with the latest developments in their field and serve as a key reference resource for the international oncology community.How are the articles written and disseminated?All articles are review-based pieces authored by opinion leaders and focus upon salient issues that impact patient care. The articles are short and concise, designed for maximum impact, aimed at senior specialists who have growing pressures on their time. These specialists are increasingly using secondary review journals to provide themselves with an efficient and insightful overview of prominent developments within their fields, and providing relevant citations for individuals who may choose to do further research.

World-renowned editorial boards are appointed from specialists in the field, which ensure that publications maintain editorial direction covering the hottest topics with all articles being subject to a rigorous peer review process. Topics and authors are selected through advice from the editorial board, internal research and the monitoring of many primary journals, conferences and physician websites. TMM produces and disseminates free-to-access content in print, online, via eBook, via monthly therapy and topic specific eNewsletters and at the major scientific meetings globally. The product is constantly improved - it includes more engaging video content online and has multiple launches planned to give clinician audiences a very valuable experience with every visit to the online therapy specific portals and to increase TMM’s database of registered users.

How can you help MASCC achieve its aims and objectives and why was a content sharing agreement developed?TMM is providing a platform globally for MASCC to share its content both in print and online. It also offers “free” branding opportunities such as premium advertising. TMM wants to provide its audience with the latest cutting edge content in supportive care in cancer. TMM is pleased to share its educational content with MASCC members.

How can members of MASCC learn more about Touch Medical Media?Go to www.touchoncology.com or at major congresses including the American Society of Clinical Oncology Congress.

Some New Supportive Care Publications by MASCC Members

Each month we present interesting papers by MASCC members. Please notify us of your publications by email to have them included.

Johnson MJ, Bland JM, Oxberry SG, Abernethy AP, Currow DC. Clinically Important Differences in the Intensity of Chronic Refractory Breathlessness. J Pain Symptom Manage. 2013 Apr 19. doi:pii: S0885-3924(13)00186-3. 10.1016/j.jpainsymman.2013.01.011.

Al-Dasooqi N, Sonis ST, Bowen JM, Bateman E, Blijlevens N, Gibson RJ, Logan RM, Nair RG, Stringer AM, Yazbeck R, Elad S, Lalla RV; For The Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO). Emerging evidence on the pathobiology of mucositis. Support Care Cancer. 2013 Apr 21.

Usmani SZ, Sawyer J, Rosenthal A, Cottler-Fox M, Epstein J, Yaccoby S, Sexton R, Hoering A, Singh Z, Heuck CJ, Waheed S, Chauhan N, Johann D, Abdallah AO, Muzaffar J, Petty N, Bailey C, Crowley J, van Rhee F, Barlogie B. Risk Factors for MDS and Acute Leukemia Following Total Therapy 2 and 3 for Multiple Myeloma. Blood. 2013 Apr 19.

M A S C C • S u p p o r t i v e C a r e m a k e s e x c e l l e n t c a n c e r c a r e p o s s i b l e

Multinational Association of Supportive Care in Cancer • www.mascc.org

Have any news items to share?

Please send contributions for the MASCC News to MASCCnews@mascc.org or the co-editors:

Anna Ugalde - anna.ugalde@svhm.org.au & Anna Boltong - anna.boltong@petermac.org

For more information please contact: Åge Schultz, MASCC Executive Director - aschultz@mascc.org

Some New Supportive Care Publications by MASCC Members (continued)

Häne H, Oberholzer R, Walker J, Hopkinson JB, de Wolf-Linder S, Strasser F. Psychosocial Consequences of Cancer Cachexia: The Development of an Item Bank. J Pain Symptom Manage. 2013 Apr 17. doi:pii: S0885-3924(13)00147-4. 10.1016/j.jpainsymman.2013.01.008.

Allcroft P, Margitanovic V, Greene A, Agar MR, Clark K, Abernethy AP, Currow DC. The Role of Benzodiazepines in Breathlessness: A Single Site, Open Label Pilot of Sustained Release Morphine Together with Clonazepam. J Palliat Med. 2013 Apr 18.

Lee CK, Brown C, Gralla RJ, Hirsh V, Thongprasert S, Tsai CM, Tan EH, Ho JC, Chu DT, Zaatar A, Osorio Sanchez JA, Vu VV, Au JS, Inoue A, Lee SM, Gebski V, Yang JC. Impact of EGFR Inhibitor in Non-Small Cell Lung Cancer on Progression-Free and Overall Survival: A Meta-Analysis. J Natl Cancer Inst. 2013 Apr 17.

Lopez-Acevedo M, Havrilesky LJ, Broadwater G, Kamal AH, Abernethy AP, Berchuck A, Alvarez Secord A, Tulsky JA, Valea F, Lee PS. Timing of end-of-life care discussion with performance on end-of-life quality indicators in ovarian cancer. Gynecol Oncol. 2013 Apr 13. doi:pii: S0090-8258(13)00230-8. 10.1016/j.ygyno.2013.04.010.

Miedema KG, Winter RH, Ammann RA, Droz S, Spanjaard L, de Bont ES, Kamps WA, van de Wetering MD, Tissing WJ. Bacteria causing bacteremia in pediatric cancer patients presenting with febrile neutropenia-species distribution and susceptibility patterns. Support Care Cancer. 2013 Apr 12.

Boers-Doets CB, Gelderblom H, Lacouture ME, Bredle JM, Epstein JB, Schrama NA, Gall H, Ouwerkerk J, Brakenhoff JA, Nortier JW, Kaptein AA. Translation and linguistic validation of the FACT-EGFRI-18 quality of life instrument from English into Dutch. Eur J Oncol Nurs. 2013 Apr 6. doi:pii: S1462-3889(13)00029-X. 10.1016/j.ejon.2013.03.004.

Chen CL, Parameswaran R. Managing the risks of cardiac therapy in cancer patients. Semin Oncol. 2013 Apr;40(2):210-7. doi: 10.1053/j.seminoncol.2013.01.006.

Bate J, Gibson F, Johnson E, Selwood K, Skinner R, Chisholm J. Neutropenic sepsis: prevention and management of neutropenic sepsis in cancer patients (NICE Clinical Guideline CG151). Arch Dis Child Educ Pract Ed. 2013 Apr;98(2):73-5. doi: 10.1136/archdischild-2013-303634.

Bate J, Gibson F, Selwood K, Skinner R, Phillips B, Chisholm JC. A reaudit of current febrile neutropenia practice in UK paediatric oncology centres prior to implementation of NICE guidance. Arch Dis Child. 2013 Apr;98(4):315-6. doi: 10.1136/archdischild-2013-303810.

Quill TE, Abernethy AP. Generalist plus specialist palliative care--creating a more sustainable model. N Engl J Med. 2013 Mar 28;368(13):1173-5. doi: 10.1056/NEJMp1215620.

Martins F, de Oliveira MA, Wang Q, Sonis S, Gallottini M, George S, Treister N. A review of oral toxicity associated with mTOR inhibitor therapy in cancer patients. Oral Oncol. 2013 Apr;49(4):293-8. doi: 10.1016/j.oraloncology.2012.11.008.

Borkar DS, Lacouture ME, Basti S. Spectrum of ocular toxicities from epidermal growth factor receptor inhibitors and their intermediate-term follow-up: a five-year review. Support Care Cancer. 2013 Apr;21(4):1167-74. doi: 10.1007/s00520-012-1645-y.

Barton DL, Burger K, Novotny PJ, Fitch TR, Kohli S, Soori G, Wilwerding MB, Sloan JA, Kottschade LA, Rowland KM Jr, Dakhil SR, Nikcevich DA, Loprinzi CL. The use of Ginkgo biloba for the prevention of chemotherapy-related cognitive dysfunction in women receiving adjuvant treatment for breast cancer, N00C9. Support Care Cancer. 2013 Apr;21(4):1185-92. doi: 10.1007/s00520-012-1647-9.

Wagner LI, Berg SR, Gandhi M, Hlubocky FJ, Webster K, Aneja M, Cella D, Lacouture ME. The development of a Functional Assessment of Cancer Therapy (FACT) questionnaire to assess dermatologic symptoms associated with epidermal growth factor receptor inhibitors (FACT-EGFRI-18). Support Care Cancer. 2013 Apr;21(4):1033-41. doi: 10.1007/s00520-012-1623-4.

To TH, Agar M, Shelby-James T, Abernethy AP, Doogue M, Rowett D, Ko D, Currow DC. Off-label prescribing in palliative care - a cross-sectional national survey of Palliative Medicine doctors. Palliat Med. 2013 Apr;27(4):320-8. doi: 10.1177/0269216312464263.