MD/PhD Program “Molecular Medicine“ - MH … Program “Molecular Medicine“ Hannover Biomedical Research School (HBRS) at Hannover Medical School Responsible Univ. Prof. Dr

MD/PhD Program “Molecular Medicine“

Hannover Biomedical Research School at Hannover Medical School

Report 2006

MD/PhD Program “Molecular Medicine“

Hannover Biomedical Research School (HBRS) at Hannover Medical School

Responsible Univ. Prof. Dr. Reinhold E. Schmidt Chairman MD/PhD Program Carl-Neuberg Str. 1 30625 Hannover Tel: 0511-532-6656 [email protected] MD/PhD committee:

Prof. Dr. A. Gossler, Prof. Dr. H. Drexler, Prof. Dr. C. Baum, Prof. Dr. C. Klein, Prof. Dr. R. Lichtinghagen, Prof. Dr. M. Gaestel, HD Dr. B. Sodeik, PD Dr. T. Tschernig, Dr. E. Jäckel, Dr. E. Hesse/ Prof. Dr. D. Gadzicki, Dr. M. Ünalan, M. Rhein, N. Heinz Dr. Susanne Kruse, Marlies Daniel MD/PhD Office

OE 9117 Carl-Neuberg Str. 1 30625 Hannover Tel. 0511-532-6011 [email protected] [email protected] Internet: www.mh-hannover.de/hbrs.html

Chairman of the MD/PhD program

The MD/PhD program “Molecular Medicine“ was established in autumn 2000. Our program has meanwhile become one of the leading PhD programs in Germany due to excellent interdisciplinary cooperation between the Hannover Medical School (MHH), the University, the School of Veterinary Medicine Hannover and the Helmholtz Center for Infection Research (HZI), Braunschweig, due to the support of the International Promotion Program (IPP) by DAAD and DFG. We are also proud to have international outstanding teachers, such as Prof. Fritz Melchers (Immunology), in our program. It is also the first German PhD program which has been accreditated according to European standards (modules ECTS). There is a good ratio between medical students and students from life sciences as well as between German and foreign students. This program attracts great national and international interest. Additionally, the MD/PhD program is the basis for the Hannover Biomedical Research School (HBRS) founded in 2003, which has been extremely successful in integrating all postgraduate programs at MHH. Joint curricula have been established. We are very proud that the HBRS is now funded (with 5 Million Euro) by the German Excellence Initiative (DFG) for the next five years. Meanwhile, more than fifty students have successfully graduated from the program. They are ambassadors for MHH around the world. Many sponsors are generously providing support for our workshop or stipends for our students. Many thanks to everyone who has supported this MD/PhD program, especially to those students who determine the excellence of the program.

Reinhold E. Schmidt, MD Professor of Medicine and Immunology

Dean of Hannover Biomedical Research School

We express our thanks to our sponsors: “Friends of MHH” Martin Lawrenz, Hannover

Table of Contents

I. Current Status, Problems and Prospects_________________________ 7

1. Current Status _____________________________________________________________________7 2. Common Rules____________________________________________________________________10 3. Cooperation with International Institutes______________________________________________11 4. Success and measures for implementation _____________________________________________12

II. Measures and Results _______________________________________ 13

1. Personnel ________________________________________________________________________13 1.1. Scientific collaborators and administrative personnel _________________________________________ 13 1.2. Tutors ______________________________________________________________________________ 14

2. Language courses _________________________________________________________________14 3. Social Activities ___________________________________________________________________14 4. Organization of Educational Material_________________________________________________15 5. Marketing Measures _______________________________________________________________15 6. Guest Lectures and additional colloquia_______________________________________________16 7. Travel ___________________________________________________________________________17 8. Visits abroad by the graduate students ________________________________________________17

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I. Current Status, Problems and Prospects

1. Current Status

Statistics Applications 2006

Country Number of applicants Now in the program

Total female male total female male

Germany 38 24 14 8 4 4

Western Europe: 7 3 4 2 1 1

Central and Eastern Europe

27 14 13 - - -

North America: - - - - - -

Latin America: 10 7 3 - - -

Africa, Subsahara: 27 9 18 - -

North Africa and Middle East:

30 13 17 1 1 -

Asia, Australia and Oceania:

271 84 187 8 6 2

Total: 410 154 256 19 12 7

Final exams in the MD/PhD program 2006:

16 students did their final exams in June and November 2006. From 17 students of the year 2003, five

did their final exams after exactly 3 years = 30%, six plan to finish after 3.5 years, six after 4 years.

Detailed Description At the moment (February 2007) there are 73 students in the program [36 women and 27 men; 51

international and 22 Germans; 18 medical students (incl. veterinary students) and 55 life scientists].

The international students come from Austria (2), Bolivia (1), China (4), Columbia (1), Estonia (1),

Ethiopia (1), Georgia (1), Hungary (1), India (30), Iran (1), Indonesia (1), Kenia (2), Mongolia (1),

Poland (1), the Netherlands (1), Ukraine (1) and Zimbabwe (1).

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The students are either financed by the corresponding departments or by scholarships (DAAD; MHH,

industry etc.). We are very happy that from 2007, HBRS will provide a number of half stipends

(1.250,-Euro/month for 18 months) for the best ten students of the ranking list after selection.

Concerning selection of the new students, a 3-step level procedure was introduced in 2002. It consists

of: 1. preselection by the PhD commission, 2. a written test in the individual home countries, 3. an

interview (in 2006 in Hannover, New Delhi and Hyderabad, India, and Harbin, China). In 2002 an

extensive application form was developed, which as further improved in 2006. Now, all programs in

the HBRS have adapted this application form.

The selection of the applicants is based on qualification only. The accepted candidates are supposed to

choose a department and a research project themselves. This means that there can be bottle-necks

regarding the guarantee of the financing of the students. For this reason scholarships were successfully

applied for in e.g. the Excellence Initiative of the German government.

In 2006, orientation weeks were organized from October 1st to 16th with the kind support of about

10.000 Euro by the DAAD (Stibet) and “Welcome in Niedersachsen” (WIN).

Students work on a 3-year research project in one of the departments of the MHH or at cooperating

institutes (see list of students). In addition, there is an obligatory program of teaching consisting of

seminars and tutorials (see list of lecturers).

In October 2003, the Graduate School: “Hannover Biomedical Research School” (HBRS) was founded

at MHH (director: Prof. Dr. R.E. Schmidt, office: Dr. S. Kruse). Here, all graduate programns [PhD

(MD/PhD “Molecular Medicine”, PhD “Infection Biology”, new PhD “Regenerative Sciences”,

Graduate Colleges (GRK 705, GRK 1441, European GRKs “Pseudomonas” and “Strategies of human

pathogens to establish acute and chronic infection”), etc.] are coordinated.

In 2004, a joint Curriculum of the HBRS [MD/PhD program, PhD program “Infection Biology”

(speaker: Prof. Dr. Förster) and Miditrain (GBF, EST Marie Curie, speaker: Prof. Dr. Hauser); GRKs]

was established in order to bundle resources.

In the first year, basics and methods of biology and medicine are taught. There are special in-depth

seminars for medical students as well as life scientists.

During the second academic year, focus lies more on current research projects (applied aspects). Since

2003, four main foci have been established in the MD/PhD program: Immunology; Infection;

Oncology and Differentiation; Genetics and Cell Biology (Fig. 2).

Besides an extensive English curriculum, guest seminars, scientific colloquia, discussions with the

supervisors and technical practical courses took place.

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Most important are the so-called “soft skills“ as well as seminars about “Research Ethics” (members of

the institute of “Science and Ethics”, Bonn), “Animal Experiments“ (Prof. Hedrich), “Scientific

Writing“ (Dr. Kruse), “Presentation techniques” (Prof. Dierks), “Intercultural communication”

(together with Göttingen), “Stress Management” (Kümmerle, Berlin), “Career perspectives” etc.

The students keep book about all seminars. The lecturers are regularly evaluated by students.

After 18 months, students give an oral intermediate exam in the respective main subject and the

subject of the co-examiner (presentation and discussion of a research paper). After 3 years the final

exam is given in form of a public disputation.

In 2006, sixteen MD/PhD students (Diya Abraham, Max-Planck Institute, India; Khaled Alkharsah,

Virology, Syria; Georg Bohn, Pediatric Hematology and Oncology, Germany; Tammy Chang,

Pediatrics, Germany; Anuhar Chaturvedi, Hematology and Oncology, India; Shipra Gupta,

Pharmacology, India; Christoph Happel, Pediatric Hematology and Oncology, Germany; Vladimira

Jakubcakova, Max Planck Institute, Slovakia; Shashi Kant, Physiological Chemistry, India; Yijiang Li,

Thoracic and Cardiovascular Surgery, China; Anika Hofmann née Meyerholz, Cell Biology, Germany;

Gesa Meyer, Toxicology, Germany; Rahul Purwar, Dermatology, India; Krishna Kumar Singh, Human

Genetics, India; Manvendra Kumar Singh, Molecular Biology, India; Linding Wang, Virology, China)

successfully finished the program. Next final exams will be on June 15th and November 9th, 2007.

The ECTS System was introduced (credit points = cp; see Fig. 1). The program was accreditated

according to European standards by ZEvA on December 9th, 2003.

Figure 1. Study Structure MD/PhD Program “Molecular Medicine“

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3-year PhD project work (125 cp) Annual presentation in department (3x; 10 cp) Journal club (3x; 3 cp) Public annual presentation/project report (3x; 10 cp) Talk/presentation on international congress (2 cp)

Basics (seminar and tutorial; 3 h per week; 8 cp)

Year 1 Year 2 Year 3

Interdisciplinary seminars/courses (60 h; 6 cp) Project-orientated seminars/courses (80 h; 8 cp)

PHD thesis

and Final exam Complex and clinical

systems (seminar and tutorial; 3 h per week; 8 cp)

Intermediate Exam after 18 months

Figure 2. Curriculum 2006/7

In September 2002, a German-wide network of biomedically orientated PhD programs was established

(currently more than 15 members). Further improvement of the coordination of selection procedures

(exams and interviews) was achieved. In 2006, the third joint workshop on “Intercultural

communication” was organized by the PhD programs of Göttingen and Hannover in Springe (Deister).

2. Common Rules

On 15.12.99, a rule for the MD/PhD program was passed by the senate of Hannover Medical School.

This rule unites a regulations for studies and exams. On 12.02.02, the MD/PhD program received

authorization from the Lower Saxony Ministry for Science and Culture to alternatively award besides

the PhD title for scientists the title Dr. rer. nat. Such changes in the rules and adaption to the program

situation were passed by the senate on 04.06.02. On 11.02.04, the rules were adapted to the

suggestions by the committee of referees for accreditation and were overall updated, same accounts for

April 2005. Currently, the PhD rules are adapted for all programs in the HBRS. In addition, special

rules and regulations for HBRS are developed.

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For all: Seminar, 2h and Tutorial, 1h

1st year

In parallel: special in-depth seminars for medical students and students from life sciences, respectively

Basics in Molecular Medicine (Focus on Methods) Seminar, 2h

Tutorial, 1h

Tutorial for the respective seminar/tutorial series

1st sem. 2nd sem.

2nd year

1. Focus: Immunology

2. Focus: Genetics & Cell Biology

3. Focus: Infection

4. Focus: Differentiation & Oncology

or

or

4th sem.3rd sem.

3rd year: concentration on individual research projects

Immunology/Stem Cell Biology/ Bacteriology/ Virology

Cell Biology/ Genetics/ Biochemistry/ Methods

3. Cooperation with International Institutes

Fortunately, within the MHH there is an active exchange, i.e. participation of almost all scientifically

active departments in the MD/PhD program – whether by means of active organizing within the

MD/PhD commission, by supervising the MD/PhD students at the research laboratories or as lecturers

in the numerous educational programs. This goes for the basic scientific as well as for the clinically

orientated departments, for example: Biochemistry, Cardiology, Cell Biology, Clinical Immunology,

Dermatology, Gastroenterology-Hepatology-Endocrinology, Genetics, Hematology, Heart and

Thoracic Surgery, Immunology, Microbiology, Molecular Biology, Nephrology, Oncology, Pathology,

Physiology, Rheumatology, Tumor Biology, Virology, Visceral and Transplantation Surgery, etc.

Therefore intensive cooperation exists between collaborators (Post-docs etc.) from Graduate Colleges

with the MD/PhD program. Moreover, the “Graduate School” (HBRS) was founded in October 2003.

There is close cooperation between the graduate and PhD programs of the School of Veterinary

Medicine Hannover, also concerning lecturers and students. In addition, there are very close

cooperations to the Helmholtz Center for Infection Biology (HZI) in Braunschweig and the Fraunhofer

Institute for Toxicology and Experimental Medicine (ITEM) in Hannover. Thanks to the scientists of

the MHH there is already intensive cooperation with European and internationally very well-known

research institutes (e.g. also by means of the two European Research Training Groups). Of course, the

PhD students profit from this cooperation, too.

A constant exchange and participation in education and research exists with the following institutes:

a) national:

• Helmholtz Center for Infection Research (HZI); Braunschweig • School of Veterinary Medicine, Hannover • Fraunhofer Institute for “Toxicology and Experimental Medicine” (ITEM), Hannover • Institute for “Animal Breeding”, Mariensee (FAL) • Center for Stem Cell Research, Gatersleben • Max-Planck Institute for Infection Biology Berlin • Leibniz University of Hannover • Technical University of Braunschweig There is intensive cooperation with these national institutes as well as concerning education (lecturers) and concerning research, i.e. making three year projects available or the function of scientists as co-supervisors.

b) international (especially with):

• Centre for DNA Fingerprinting (CDFD), Hyderabad, India With Prof. Dr. S. Hasnain there has been intensive contact since 2002 (see guest lecturer and trip to India). The establishment of a mutual “summer school“ is planned and the exchange of scientists will be realized within the Indo-German Science Center.

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c.) Economy/Industry (especially with):

Solvay GmbH Hannover, Bayer Schering Pharma AG Berlin and Novartis GmbH Basel

Industry excursions (e.g. Solvay AG, Hannover; Bayer AG, Research Center, Wuppertal) are regularly

taking place.

4. Success and measures for implementation

In 2006, sixteen students successfully finished the MD/PhD program (see above). Some of the finalists

continue to work at MHH or German universities (medical consultant, Postdoc etc.). Nine of them

already plan or went to work as Postdocs abroad (Canada. UK, USA, China, Switzerland, Sweden).

The MD/PhD program has established an ALUMNI organization and student’s network. In 2006, the

first Alumni newsletter was created. Furthermore, an Alumni survey was performed, which showed

very positive responses.

The MD/PhD program plays a key role (scientific, organization) in Hannover Biomedical Research

School (HBRS).

In 2006, MHH was very successful in the German Excellence Initiative. HBRS (with its MD/PhD

program „Molecular Medicine“) will be supported with 5 Million Euro for the next five years. This

includes the position of the scientific coordinator Dr. Kruse, 25 „half“ PhD stipends (18 months) per

new year, language teachers, student tutors, marketing, invitation of guest lecturers, soft skills, summer

schools, teaching aids, flexible funds, selection processes, travel of coordinators, support of student’s

travel to congresses, child care.

Furthermore, the accreditation (see above) implements the program.

The program was very successful in gaining sponsors, either for the annual workshop, the year book or

for student’s grants (see list on page 6). A sponsoring concept as well as special flyers were developed.

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II. Measures and Results The MD/PhD Program “Molecular Medicine“ started in winter semester 2000/01. From 2002 to 2006,

the program was supported by the DAAD/DFG by means of the “International Promotion Program”

(IPP). From 2007, the program will be supported by means of the German Excellence Initiative for the

Hannover Biomedical Research School (HBRS).

1. Personnel

Within the IPP the posts for a scientific coordinator (full time) and funds for assistant students (see

“non scientific care”; 10 hours/week) have been granted.

1.1. Scientific collaborators and administrative personnel

Since 01.05.2002, Dr. Susanne Kruse has been working on the program as scientific coordinator. She

has various tasks; she is responsible for the total coordination and organization of the MD/PhD

program and HBRS, e.g.

• Consultation of the PhD students and applicants

• Organization and coordination of the application and selection procedure

• Cooperation with the PhD commission and HBRS

• Processing of the PhD commission meetings

• Contact to supervisors and lecturers of the Medical School and cooperating institutes

• Public relations (articles, homepage design etc.)

• Marketing (flyers, poster, advertisements etc.)

• Fund raising (incl. sponsors); applications (DFG, BMBF etc.)

• Planing and coordination of the curriculum (including “Soft skills”)

• Organization of workshops/seminars

• Presentation of the seminar “Scientific Writing“

• Evaluation of seminars and tutorials

• Preparation of exams and coordination

• Organization of the inauguration, non scientific care and social activities

• Contact to DAAD and other PhD programs (esp. MD/PhD Network)

• Administration of the budget

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Mrs. Marlies Daniel works at the PhD Office (full time) as person in charge/correspondant. Her

position is financed by the Hannover Medical School.

Mrs. Daniel supports Dr. Kruse with the coordination und organization of the MD/PhD program. She

is responsible for the total correspondence, telephone calls, organization of the application procedure,

organization of events, taking care of the students (esp. during the training period: organization of

accommodation, banks, insurance etc.), statistics etc.

1.2. Tutors

In 2006, Tracey Gillman has been employed as assistant student on an hourly basis. She especially

takes care of the MD/PhD students in close cooperation with the “International Office”, helps at

German authorities, supports International evenings.

2. Language courses

Mrs. Petra Marotz has been employed as the German teacher since 01.10.2002 (hourly basis). Mr

Andre Brana was hired initially for the orientation weeks 2006. Both teach 2 hours/week. This

concerns a course for beginners and an advanced course (1 year experience). A total of over 20 PhD

students of HBRS participate in the courses.

3. Social Activities

• On 14.01.06 an Indian evening was organized.

• On 09.06.06, final exams of 7 MD/PhD students took place.

• On 12.07.06, eight students participated in an excursion to the biotech company ”Qiagen GmbH“

in Hilden, organized by the PhD program “Molecular Biology” in Göttingen.

• On 20.07.06, summer term was closed with an international barbecue for all PhD students,

lecturers and supervisors in HBRS.

• On 26.07.06, students visited the opera house Hannover (Ballet „Bolero“), in cooperation with the

International Office.

• On 09.09.06, a day excursion to Langeoog was organized in close cooperation with the

International office.

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• Orientation weeks (03.10.-16.10.06) were financially supported by the “WIN“ program (Welcome

in Niedersachsen) of Lower Saxony.

• The opening of term / welcome of new students was celebrated on 16.10.06. All students,

supervisors and lecturers of the MD/PhD program “Molecular Medicine“, the PhD program

“Infection Biology”, the Research training sites, the Master program “Biomedicine” as well as the

president of MHH and several guests (e.g. State secretary Dr. Lange, MWK; International

Advisory Board of HBRS) participated. Invited speaker was Prof. Kalden (University of Erlangen;

see also 6.), musical introduction by: Anna Piechotta + Band.

• On 10.11.06, the festive ceremony after the final exams took place. Invited guest speaker was Prof.

Dr. Yves Barral (ETH Zürich) (see also under 6.), musical introduction by Nora Teschner

(Cellotrio).

• On 12.11.06, an excursion/walk to the Süntel (Bad Münder) was organized.

• On 25.11.06, the Indian Diwali festival was celebrated.

• On 05.12.06, students visited the Christmas Market in Hannover city center.

• On 14.12.06, an international Christmas Party was celebrated with all students, supervisors and

lecturers of HBRS (all programs).

4. Organization of Educational Material

An HBRS study room was established. Laptops and major text books were purchased for student’s

use.

5. Marketing Measures

• A large number of ads were published in Nature, Science, New Scientist, Laborjournal etc. The

resonance was enourmous (400 applications).

• A year book 2005 was printed.

• On 21.02.06, an info meeting on the MD/PhD program was organized for students/candidates.

• Because of the accreditation, the MD/PhD program serves as a model and advisor for lots of other

national and international programs.

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6. Guest Lectures and additional colloquia

• From 12.01.-13.01.06, a workshop on „project management“ was organized by the GRK

„Characterization of pathophysiological animal models“. Four students of the MD/PhD program

participated.

• On 20.01.06, Dr. Kruse held the seminar “Scientific writing“ at MHH.

• From 06.-08.03.06 and from 06.-09.11.06, Prof. Hedrich and colleagues held the course “Animal

Experiments“ for HBRS students at MHH.

• From 09.-11.03.06, the annual Stephansstft Workshop (retreat) was taking place. Students had to

present and discuss their projects with all participants (students, supervisors, lecturers). In addition

assemblies of students as well as lecturers/supervisors were organized. The international evening

was planned for Friday. The workshop was financially supported by a number of sponsors.

• On 04.5.06 the written test for new applicants was given at MHH. In addition, tests were organized

in home countries of candidates.

• On 09.06.06, seven MD/PhD students had their final exams (public defenses; in English). At least

one external examiner was invited (Blackbourn, Birmingham, England; Schlitt, Regensburg;

Albrecht, Fribourg, Switzerland; Jeltsch, Bremen; Maronde, Frankfurt; Boileau, Paris, France;

Brand, Würzburg; Gessler, Würzburg). The official festive act was celebrated on 10.11.06 (see

below). During their stay in Hannover, some of the external reviewers gave guest lectures talking

about their own research results.

• From 16.-18.06.06, the workshop “Intercultural Communication“ took place in Springe (near

Hannover) in a joint effort of PhD programs in Göttingen and Hannover.

• Altogether 73 applicants were invited for interview in Hannover, New Delhi (India; DAAD office),

Hyderabad (India; CDFD) and Harbin (China) in June/ July 2006. Candidates had to give short

presentations of previous experimental work and were asked questions (total 20 min).

• From 20.-21.07.06, the workshop “Presentation techniques“ was offered by Prof. Dr. Dierks

(MHH). Aim was to prepare students for presentations on congresses, meetings etc.

From 18.-19.09.06, the seminar „Gene Technology Security“ was organized by Dr. Mertsching (Gene

Security Officer). The course was given at MHH for the third time in English. Participants receive a

certificate, which enablees to work as project leader in the field of genetechnology and working with

pathogenic microorganisms.

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• On 16.10.06, the opening of the new study year was celebrated. Guest speaker was Prof. Dr. J.

Kalden (University Clinics of Erlangen). In addition, members of the international advisory board

of HBRS were invited: Molin, Copenhagen, Denmark; Weber, Zürich, Schwitzerland; Cohen,

Dundee, Scotland.

• On 23.10.06, Prof. Melchers gave lecture in course of the HBRS curriculum.

• On 10.11.06, the final exams (public defense; in English) was organized for nine MD/PhD

students. At least one external examiner was invited (Johnsson, Münster; Bruder, Braunschweig;

Radeke, Frankfurt; Schäkel, Dresden; Niehues, Düsseldorf; Stürzl, Erlangen; Häußler,

Braunschweig; Seternes, Tromsoe, Norway). On the evening of the festive ceremony, Prof. Dr.

Yves Barral (ETH Zürich) was invited as guest speaker. Musical introduction was given by Nora

Teschner. During their stay in Hannover, some of the external reviewers gave guest lectures talking

about their own research results.

7. Travel

• From 22.-23.02.06, Dr. Kruse participated in the DAAD ECTS Workshop (Medicine/Public

Health) in Dresden.

• From 02.-03.05.06, Dr. Kruse and Prof. Dr. R. E. Schmidt travelled to the IPP (DAAD) annual

meeting in Bonn.

• From 18./19.05.06, Dr. Kruse participated in the meeting on „Alumni and graduate surveys”

organized by the university of Kassel.

• From 09.-12.06.06, Prof. Dr. R.E. Schmidt travelled to Calcutta (India) and the Indo-German

Science Center.

• From 03.07.-07.07.06, Dr. Kruse, Prof. Dr. C. Klein, Dr. Oliver Pabst and Prof. Dr. R. E. Schmidt

performed interviews with 30 Indian applicants in the DAAD office New Delhi and at CDFD

Hyderabad. From these applicants, nine were selected for the MD/PhD program.

8. Visits abroad by the graduate students

• Altogether 73 applicants were invited for interviews in June/July 2006 (see above).

• For all new students travel costs to Hannover were supported by the “WIN” program (see above)

• Overall, the MD/PhD students attended numerous meetings, congresses and short research stays

abroad. They were supported by the departments, DAAD, DFG etc.

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Year 2002

Aravind Sekhar

EducationCollege/University:1996-2002 Bangalore Medical College, Bangalore

Highest degree:M.B.B.S.(Bachelor of Medicine & Surgery)

Major Subjects:Medicine, Surgery, Obstetrics & Gynaecology

Projects/Research:Genes specifically expressed in intestine epithelium

Scholarships:JNCASR Summer Research Fellowship `98

Scientific Interests and Goals:Developmental biology

Hobbies and other interests:Travel, Reading, Rock Music, Calligraphy

First name:Aravind

Last name:

Sekhar

Date of birth:19.04.1978

Country:India

E-mail:[email protected]

Supervisor:Prof. Dr. A. GosslerMolecular Biology

Year 2003

Dorothea Dijkstra

Dorothea Gadzicki

Jaba Gamrekelashvili

Arnab Ghosh

Eric Hesse

Kumaravelu Jagavelu

Gustavo Salguero Lopez

Harini Nivarthi

Andri Pramono

Bishnudeo Roy

Tibor Veres

Anastassiia Vertii

First Name:Dorothea (Dorrit)

Last Name:Dijkstra

Date of Birth:28.10.1977

Country:The Netherlands


Supervisors:Prof. Dr. T. WerfelDr. R. GutzmerDermatology

EducationCollege/University:1995-1999 Hogeschool IJsselland, Deventer, The

Netherlands1999-2001 Vrije Universiteit, Amsterdam, The

Netherlands

Highest degree:MSc (Drs.)

Major Subjects:Immunology, Dermatology, Pharmacology

Scientific Interests and Goals:To find out the role of anaphylatoxins C3a and C5a and their respective receptors in modulating the interaction between dendritic cells and T-lymphocytes in the skin. We will compare healthy subjects and patients with chronic inflammatory skin diseases as a model.

Hobbies and other interests:Parasitology (fascinating how they escape from host immune responses!), World Wildlife Foundation, Windsurfing, Skating, Friends, Drawing, Reading, Music, my parents dog Rocaille etc.

EducationCollege/University:1994-2001 Medizinische Hochschule Hannover, Germany

Highest degree:MD (Dr. med.)

Major Subjects:Genetics, Tumorigenesis

Projects/Research:Identification of secondary genetic changes in BRCA1/2-induced hereditary breast cancer development

Scholarship/Award:Junior Professorship for Hereditary Breast Cancer awarded bythe Lower Saxony Ministry of Science and Culture, Dorothea Erxleben Program (from November 2005)

Scientific Interests and Goals:To gain insight into fundamental molecular processes duringbreast cancer development, in particular of hereditary breastcancer, to improve the diagnostic procedures and adapttherapeutic strategies for a better prognostic outcome.

Hobbies and other interests:Literature, theatre, sports, drawing

Publications:- Gadzicki D, Müller-Vahl KR, Heller D, Ossegge S, Nöthen MM, Hebebrand J, Stuhrmann M (2004) Tourette Syndrome is not caused bymutations in the central cannabinoid receptor (CNR1) gene. Am J MedGenet B Neuropsychiatr Genet 127:97-103- Gadzicki D, von Neuhoff N, Steinemann D, Just M, Busche G, Kreipe H, Wilkens L, Schlegelberger B. (2005) BCR-ABL gene amplification and overexpression in a patient with chronic myeloid leukemia treated with imatinib. Cancer Genet Cytogenet 159:164-7- Gadzicki et al. Communicating BRCA1 and BRCA2 genetic test results.(2006) J Clin Oncol 24:2969-70- Gadzicki D, Baumer A, Wey E, Happel CM, Rudolph C, Tönnies H, Neitzel H, Steinemann D, Welte K, Klein C, Schlegelberger B. (2006) Jacobsen syndrome and Beckwith-Wiedemann syndrome caused by a parental pericentric inversion inv(11)(p15q24). (2006) Ann Hum Genet 70:958-64. - Ansgar Gerhardus, Henriette Schleberger, Brigitte Schlegelberger, Dorothea Gadzicki. (2007) Diagnostic Accuracy of Methods for the Detection of BRCA1 and BRCA2 Mutations. A Systematic Review. Eur J Hum Genet (in press)

First name:

Dorothea

Last name:Gadzicki


Country:Germany


Supervisor:Prof. Dr. B. Schlegelberger,Cell and Molecular Pathology

EducationCollege/University:1996-2002 Tbilisi State Medical University, Tbilisi Georgia

Highest degree:MD

Major Subjects:Basic and tumor Immunology

Projects/Research:Influence of tumor cell death on tumor-specific immune responses

Scientific Interests and Goals:Mechanisms of immune tolerance & activation in tumor immunity

Hobbies and other interests:Table tennis, football, neuroscience.

Publications:Garbe AI. Vermeer B. Gamrekelashvili J. von Wasielewski R. Greten FR. Westendorf AM. Buer J. Schmid RM. Manns MP. Korangy F. Greten TF. Genetically induced pancreatic adenocarcinoma is highly immunogenic and causes spontaneous tumor-specific immune responses. Cancer Res. 2006 Jan 1;66(1):508-16.

Nizharadze N. Gongadze M. Sanikidze T. Gamrekelashvili J. Sumbadze C.Kevlishvili O. Effects of LPS on the proliferating processes in splenocytes. Proc. Georgian Acad. Sci., Biol., Ser. A., 2002, vol. 28, #5-6 pp. 573-576.

First name:

Jaba

Last name:Gamrekelashvili


Country:Georgia


Supervisor:PD.Dr. T. GretenDepartment of Gastroenterology,Hepatology & EndocrinologyMH Hannover

EducationCollege/University:1996-2001 Mysore Medical College, India

Highest degree:MBBS

Major Subjects:Medicine

Projects/Research:Mechanisms and modulation of anti-leukemia immunity

Scientific Interests and Goals:To obtain further insights into management of childhoodleukemia

Hobbies and other interests:Exploring Indian wildlife; Anthropology and development of languages

First name:

Arnab

Last name:Ghosh


Country:India


Supervisor:PD Dr. M. SauerPediatric Hematology and Oncology

EducationCollege/University:since 2005 Yale University School of Medicine, USA1996-2005 Hannover Medical School, Germany

Harvard University Medical School, USAUniversity of Birmingham, GBUniversity of Otago, New ZealandUniversity of Zurich, SwitzerlandUniversity of Cape Town, South Africa

Highest degree:MD

Major Subjects:Cell- and Molecular Biology

Projects/Research:Regulation of osteoblastogenesis and bone formation

Scientific Interests and Goals:Bone Biology

Scholarship:1. Endocrine Fellows Foundation Award2. DFG Research Fellowship3. I-lab Award, Aventis Foundation4. Hannelore Munke Research Award, MHH5. DAAD Fellowship6. Scholarship, Bayer Leverkusen Foundation

Hobbies and other interests:Sports, Literature

Publications:Hesse E, Rosenthal H, Brabant G, Laenger F, Gratz KF, Bastian L.Manuscript submitted

Hesse E, Moessinger E, Rosenthal H, Laenger F, Brabant G, Petrich T, GratzKF, Bastian L. J Bone Miner Res. 2007 Jan, Vol. 22, No 1. 158-62. Epub2006 Oct 2.

Hesse E, Jagodzinski M, Wehmeier M, Horne WC, Baron R. J Bone Miner Res. 2005 Sep, Vol. 20, S356

Hesse E, Musholt PB, Potter E, Petrich T, Wehmeier M, von Wasielewski R, Lichtinghagen R, Musholt TJ. Br J Cancer. 2005 Sep 5;93(5):565-70

Hesse E, Bastian L, Zeichen J, Pertschy S, Bosch U, Krettek C. Knee SurgSports Traumatol Arthrosc. 2006 Apr;14(4):335-9. Epub 2005 Jun 10.

First name:

Eric

Last name:Hesse


Country:Germany


Supervisor:Prof. Dr. R. Baron (PhD, DDS)Dr. W.C. Horne (PhD)(Orthopaedics and Cell Biology,Yale University)

Prof. Dr. C. Krettek (MD)(Trauma Surgery,Hannover Medical School)

EducationCollege/University:1997-1999 Bharathidasan University, Trichy, India

Highest degree:M.Sc.

Major Subjects:Microbiology

Projects/Research:Involvement of the p38-MK2 signaling pathway in artherogenesis

Scientific Interests:Developmental Biology

Hobbies and other interests:Photography, Lepidoptery, Travelling

Publications:Kumaravelu J, Shanmugasundaram GK, Unwala H, Ramamoorthi N, Banerjea AC. Genes and Immunity 2001; 2, 404-407.Ramamoorthi N, Kumaravelu J, Shanmugasundaram GK, Rani K, BanerjeaAC. Genes and Immunity 2001; 2, 408-410.

First name:Kumaravelu

Last name:Jagavelu


Country:India

E-mail:[email protected]@hotmail.com

Supervisor:Prof. Dr. B. SchiefferCardiology

EducationCollege/University:1995-2001 Universidad Nacional de Colombia, Bogota Colombia

Highest degree:MD

Major Subjects:Cellular and molecular biology of cardiovascular diseases: Cellular and molecular mechanisms of angiogenesis.Role of progenitor cells in neovascularization

Projects/Research:Impact of biomechanical stretch in progenitor cell differentiation. Role of progenitor cells in Hypertension

Scientific Interests and Goals:My main goal is to apply the knowledge from research in molecular biology on the understanding of cardiovascular diseases. As a first approach I am working on in vitro and in vivomodels of vascular hypertension at a cellular and molecular level. It will open me new perspectives about potential applications of molecular technology and their impact on diagnostic and prevention strategies and more specific and effective treatments for these kind of diseases.

Hobbies and other interests:Take a walk by the mountains. Good music and literature.

First name:

Gustavo

Last name:Salguero


Country:Colombia


Supervisor:Prof. Dr. B. SchiefferCardiology and Angiology

EducationCollege/University:B.Sc. Biochemistry, Daulat Ram College, Delhi Univrsity.M.Sc. Biotechnology, Madurai Kamaraj University

Highest degree:Master

Major Subjects:Biotechnology, Biochemistry

Projects/Research:Molecular analysis of transcription factors involved in dendritic cell developmernt

Hobbies and other interests:Reading, Indian classical dance.

First name:

Harini

Last name:Nivarthi


Country:India


Supervisor:Prof. Dr. C. KleinPediatric Hematologyand Oncology

EducationCollege/University:1999 B.Sc. University of Indonesia, Indonesia2003 M.Sc. University of Indonesia, Indonesia

Highest degree:M.Sc. in Microbiology Medicine

Major Subjects:Cell Biology, Embryonic Stem Cell

Projects/Research:Analysis of Thrombopoetin function on hematopoeticdifferentiation in mouse embryonic stem cell

Scientific Interests and Goals:My interest unravelling molecular mechanism of hematopoiesis in embryonic stem cell.

Hobbies and other interests:Playing piano, watching movie.

Publications:

Rekiansyah M, Pramesyanti A, Bella B, Kosasih H, Ma‘roef CN, Tobing SY, Rudiman PI, Alisjahbana B, Endi TP, Green S, Kalayanarooj S, Rothman AL, Sudiro TM. Southeast Asian J. Trop. Med. Public Health. 2005 ;36(5) :1187-1197.

Wang Z, Skokowa J, Pramono A, Ballmaier M, Welte K.Ann NY Acad Sci. 2005; 1044:29-40.

First name:Andri

Last name:Pramono


Country:Indonesia


Supervisor:Prof. Dr. K. WeltePediatric Hematology and Oncology

EducationCollege/University:2001-2003 School of Biotechnology, Madurai Kamaraj University, Madurai, India

Highest degree:MSc in Biotechnology

Major Subjects:Biotechnology

Projects/Research:Contribution of B1 cells to the gut associated humoral immunity.

Scholarships •Received DBT (Department of Biotechnology, India) studentship during my MSc.• Junior research fellowship (JRF) awarded by Counsil for Scientific and Industrial Research (CSIR), India

Scientific Interests and Goals:I Have a particular interest in understanding the complexity ofthe regulation of immune responses.

First name:

Bishnudeo

Last name:Roy


Country:India


Supervisor:Dr. S. WeissMolecular ImmunologyHZI Braunschweig

EducationCollege/University:1996-2003 Semmelweis University Budapest, Hungary

Highest degree:MD

Major Subjects:Respiratory Immunology

Projects/Research:Interaction between pulmonary dendritic cells and nerves duringallergic airway inflammation

Scientific Interests and Goals:Understanding the mechanisms of cross-talk between thenervous and immune system and investigating the contributionof neuroimmune interactions to allergy

Hobbies and other interests:Music, literature, languages, hiking

Publications:Vannay A, Fekete A, Muller V, Strehlau J, Viklicky O, Veres T, Reusz G, Tulassay T, Szabo AJ. Kidney Blood Press Res. 2004;27(2):105-13.

Sander LE, Lorentz A, Sellge G, Coeffier M, Neipp M, Veres T, Frieling T, Meier PN, Manns MP, Bischoff SC. Gut. 2005 Nov 18

First name:

Tibor

Last name:Veres

Date of birth:11. 06. 1978

Country:Hungary


Supervisor:PD Dr. BraunFraunhofer-Institute forToxicology and Experi-mental Medicine

EducationCollege/University:1993-1998 Kharkov State University -Kharkov, Ukraine2001-2003 Kadir Has University-Istanbul, Turkey

Highest degree:MSc in Biology

Major Subjects:Molecular Biology, Protein Interaction, Heat Shock Proteins

Projects/Research:Search for biological functions of Hsp25 phosphorylation

Scientific Interests and Goals:Hsps have essential cellular functions. This is the pillow thatprovides us with „soft landing“ once we fall unexpectedly. So I will try to learn how it works in details.

Hobbies and other interests:Alpine skiing (Bad Grund Club), Diving (PADI), Thai-Chi, meditation; Street cats (“Sokak Melek”, “SED”)

Publications:Memon A., Aktoprakligil D., Ozdemir A., Vertii A. Turk J. Bot 2001; 25:11-121

Duman BS, Turkoglu C, Akpinar B, Guden M, Vertii A, Dak E, Cagatay P, Gunay D, Buyukdevrim AS. Arch Pathol Lab Med. 2004 Aug;128(8):869-74.

Duman BS, Turkoglu C, Akpinar B, Guden M, Vertii A, Cagatay P, Gunay D, Sevim Buyukdevrim A. Ann Hum Biol. 2005 Sep-Oct;32(5):620-9.

A. Vertii, C. Hakim, A. Kotlyarov and M. Gaestel. J Biol Chem 2006 Sept; 281(37): 26966-26975.

First name:

Anastassiia

Last name:Vertii


Country:Ukraine


Supervisor:Prof. Dr. M. GaestelDr. A. KotlyarovInstitut für Biochemie/Physiologische Chemie

Year 2004

Rannar Airik

Abdul Mannan Baru

Adan Jirmo Chari

Sangeeta Chauhan

Mingmin Chen

Prajeeth C.K.

Gamze Kabalak

Khurshed Iqbal

Joanna Jagielska

Nonsikelelo Mpofu

Frederick Onono

Erkembulgan Purevdorj

Aeheli Choudhury Roy

Jessica Schwermann

Meera Shah

Anurag Singh

Kirsten Sommer

Leena Srivastava

Basant Thakur

Murat Ünalan

Fei Zhao

EducationCollege/University:1998-2004 University of Tartu, Estonia

Highest degree:M.Sc. in Developmental biology

Major Subjects:Developmental Biology, Molecular Biology

Projects/Research:Analysis of the function of the T-box gene Tbx18 in the murinekidney development

Scientific Interests and Goals:To get further insights into the mechanism of tissue and organ patterning in early mammalian development.

Hobbies and other interests:Movies, literature, etc.

Publications:Airik R, Bussen M, Singh MK, Petry M, Kispert A. Tbx18 regulates the development of the ureteral mesenchyme. J. Clin. Invest 2006; 116:663-674

First name:Rannar

Last name:Airik


Country:Estonia


Supervisor:Prof. Dr. A. KispertMolecular Biology

First Name:Abdul Mannan

Last Name:Baru


Country:India


Supervisor:Prof. Dr. G. BehrensClinical Immunology

EducationCollege/University:1996-1999 Bachelors in Microbiology, Mumbai University, India1999-2001 Masters in Microbiology, Mumbai University, India

Highest Degree:Masters in Microbiology

Major subjects:Genetics, Biochemistry, Biotechnology, Medical and Industrial Microbiology

Project / Research:1.) Roads to Presentation: Targeting the pathways in antigen uptake to dissect out mechanisms for cross presentation.2.) Differentiation and characterization of dendritic cells from HOXB4 transduced haematopoietic stem cells

Credentials and scholarships:• Topped Mumbai University in Microbiology at Bachelors level.• Worked as a Junior Research Fellow at TIFR, Mumbai, under Indo-Frenchcollaborative grant.• Worked as a Senior Research Fellow at TIFR, Mumbai under ICMR grant.

Scientific Interest and goals:To understand and characterize the cells and processes involved in immune protection.

Hobbies and other interests:Stage, Reading, Music.

PublicationsB.A. Mannan, K. Patel, I. Malhotra, B. Ravindran & Shobhona Sharma. How specific is the immune response to malaria in adults living in endemic areas? J. Vector Borne Dis. 2003; 40: 84-91.K. Aruna, Tirtha Chakraborty, Savithri Nambeesan, Abdul Baru Mannan, Alfica Sehgal, Seema R Bhalchandra and Shobhona Sharma. Identification of a hypothetical membrane protein interactor of ribosomal phosphoprotein P0. J. Biosciences 2004, 29:33-43.

EducationCollege/University:1994-1998 B.Sc (honours) Moi Univ.-Kenya2000-2003 M.Sc (Immunoparasitology) University of

Nairobi-Kenya

Highest degree:M.Sc (Immunoparasitology)

Major Subjects:Immunology,Virology and Parasitology

Projects/Research:Assessment and Modulation of dendritic cell induced CD8+T cell responses to HSV-1 epitopes. Differential antigenacquisition and presentation potential of murine splenic DC

Scientific Interests and Goals:Elucidation of scientific principles and their translation intobeneficial-societal use

Hobbies and other interests:Soccer, Chess and Charting with friends

First name:Adan

Last name:Chari Jirmo


Country:Kenya

E-mail:[email protected]@mh-hannover.de


EducationCollege/University:2001-2003 University of Jammu, M.Sc in Biotechnology.

Highest degree:M.Sc. in Biotechnology


Projects/Research:1. Construction and characterization of cDNA library of Plantagoovata.2. Regulation of the turn over of mitotic cyclins and their role in the development of human malignancies.

Scholarships:1. Awarded by DBT,india for selection in All india combinedM.Sc. biotechnology program. (2001-2003).2. Junior Research Fellowship (JRF) awarded by Council forScientific and Industrial Research (CSIR), India.

Scientific Interests and Goals:My main field of interest is cell biology and oncology, I want to study cell cycle and its regulation . I would consider myself to be successful in my ambition if I am in any way able to add to the knowledge that will ultimately help us to understand this fascinating area of biology.

Hobbies and other interests:Music, Movies, literature, etc.

First name:Sangeeta

Last name:Chauhan


Country:India


Supervisor:Dr. N.P. MalekMolecular Biology

EducationCollege/University:1999-2003 BSc. in Biological Science, Ningbo University, China2003-2004 MSc. in Molecular Genetics, the University of

Leicester, UK

Highest degree:MSc. in Molecular Genetics

Major Subjects:Genetics, Biochemistry and cellular biology

Projects/Research:The function of PDZ domain proteins in ion transport and the signalpathways by regulated cytoproteins.

Scientific Interests and Goals:To identify certain signal pathways on ion transport and theirdifferent physiological affection on ion absoption and secretion.

Hobbies and other interests:Relaxing and lying on somewhere with cool soft drinks and wonderful performance.

First name:Mingmin

Last name:Chen


Country:China


Supervisor:Prof. Dr. U. SeidlerGastroenterology, Hepatology & Endocrinology

EducationCollege/University:1997-2000 Bachelor of Science (Microbiology)

Osmania University, Hyderabad, India2001-2003 Master of Science (Biotechnology)

MKU, Madurai, India

Highest degree:Master of Science: Biotechnology


Projects/Research:Effects of MALP-2 on antigen presentation and cross-presentation by dendritic cells.

Scientific Interests and Goals:To translate molecular research into clinical diagnostics and therapeutics

Hobbies and other interests:Sports, Music

First name:Prajeeth

Last name:C.K


Country:India



EducationCollege/University:1998-2000 University of Greifswald, Germany2000-2002 University of Heidelberg, Germany2003 Diploma in Pharmacy

(University of Greifswald)

Highest degree:Dipl. pharm.

Major Subjects:Immunology, Human genetics

Projects/Research:Genetic risk factors of autoimmune diseases: Multiple Sclerosis, Sjögren’s syndrome and Systemic lupus erthematosus

Scientific Interests and Goals:My main interest is to study new targets and the development of therapeutics.

Hobbies and other interests:singing, guitar, meeting with friends, cinema

First name:Gamze

Last name:Kabalak


Country:Germany


Supervisor:PD Dr. T. WitteClinical Immunology

EducationCollege/University:1998-2000 M.Sc. In Biotechnology, HPU, Shimla, India.2001-2002 Diploma in Bioinformatics, JNU, Delhi, India.

Highest degree:M.Sc. in Biotechnology, Advanced Diploma in Bionfomatics

Major Subjects:Biotechnology and Computational Biology

Projects/Research:To unravel Telomeres and Telomerase activity in BovineEmbryos and Stem cells

Scientific Interests and Goals:To execute innovative and value-added research

Scholarships:Research Fellowsip by Council for Scientific and Industrial Reseach (CSIR), ICMR and Department of Biotechnology, India.

Hobbies and other interests:Travelling, Movies, Reading and Exploring „The Deutschland“.

First name:Khursheed

Last name:Iqbal


Country:India


Supervisor:Prof. Dr. H. Niemann

Department ofBiotechnology,Institute of Animal Sciences(FAL), Mariensee

EducationCollege/University:1996-1999 Bachelor of Science Honours Degree in

Biochemistry,University of Zimbabwe, Zimbabwe2002-2004 Master of Science Degree in Molecular Biology ,

Vrije Universiteit Brussel, Belgium

Highest degree:MSc in Molecular Biology

Major Subjects:Biochemistry and Molecular Biology

Projects/Research:Antigen-specific regulatory T-cells for control of auto- and alloimmune responses

Scientific Interests and Goals:To understand the molecular basis of human diseases and to apply this knowledge in the developmemnt of new therapies.

Hobbies and other interests:Traveling, Reading, Singing, meeting new people and learningabout new cultures

First name:Nonsikelelo

Last name:Mpofu


Country:Zimbabwe


Supervisor:Dr. E. JaeckelGastroenterology, Hepatology& Endocrinology

EducationCollege/University:1997 Jomo Kenyatta University of Agriculture and Technology-

Kenya, BSc(Biochemistry and Chemistry)

2003 University of Nairobi –Kenya MSc in Biochemistry

Highest degree:MSc in Biochemistry

Major Subjects:Biochemistry

Projects/Research:Farnesyl Transferase Inhibitor (FTI) Modulation of Topoisomerase

IIα Inhibition efficacy in Myloid Leukemia

Scientific Interests and Goals:Interested in Biological Signalling and its role in controlling

disease

Hobbies and other interests:Long distance Running, Eating free food, Arguing and Sleeping

Publications:Graham SP, Pelle R, Honda Y, Mwangi DM, Tonukari NJ, Yamage M, Glew

EJ, de Villiers EP, Shah T, Bishop R, Abuya E, Awino E, Gachanja J, Luyai AE, Mbwika F, Muthiani AM, Ndegwa DM, Njahira M, NyanjuiJK, Onono FO, et al. Theileria parva candidate vaccine antigensrecognized by immune bovine cytotoxic T lymphocytes. Proc Natl AcadSci U S A. 2006 Feb 21; [Epub ahead of print]

First name:

Fredrick Onyango

Last name:Onono


Country:Kenya


Supervisor:PD Dr. C. ReuterHematology and Oncology

EducationCollege/University:1992-1998 MD National Medical University of Mongolia1999-2001 MSc Medical Genetics NMUM

Highest degree:MD, MSc

Major Subjects:Medical Genetics, Cell Biology

Projects/Research:ErB4 in fetal surfactant synthesis

Scientific Interests and Goals:To study molecular and cellular aspects of prenatal and postnatal disorders, to contribute to the development of biomedicalresearch in my country.

Hobbies and other interests:Sports, Travel

First name:Erkhembulgan

Last name:Purevdorj


Country:Mongolia


Supervisor:Dr. C. DammannPediatric Pulmonologyand Neonatology

EducationCollege/University:1999-2002 BSc (Hons.) Microbiology,Gargi College, Delhi

University, New Delhi, India2002-2004 MSc Biotechnology, AIIMS, New Delhi, India

Highest degree:MSc Biotechnology

Major Subjects:Microbiology, Immunology, Molecular Biology

Projects/Research:Analysis of the sequence of telomere dysfunction followed bytelomerase activation during aging and carcinogenesis

Scientific Interests and Goals:To translate molecular research into clinical diagnostics and therapeutics

Hobbies and other interests:Reading, Philately, Numismatics, Origami

Publications:Choudhury AR, Ju Z, Djojosubroto MW, Schienke A, Lechel A, Schaetzlein S, Jiang H, Stepczynska A, Wang C, Buer J, Lee HW, von Zglinicki T, Ganser A, Schirmacher P, Nakauchi H, Rudolph KL. Cdkn1a deletion improves stem cellfunction and lifespan of mice with dysfunctional telomeres withoutaccelerating cancer formation. Nat Genet. 2007 Jan;39(1):99-105.

First name:Aaheli

Last name:Roy Choudhury


Country:India


Supervisor:Prof. Dr. K. L. RudolphGastroenterology, Hepatology& Endocrinology

EducationCollege/University:1998-2004 TFH-Berlin, Germany 2002 Dublin City University, Ireland2003 Baylor College of Medicine, Houston, TX, USA

Highest degree:Dipl. Ing. (FH)

Major Subjects:Pharmaceutical & Chemical Engineering

Projects/Research:Interaction between the p38 MAP kinase signaling cascade and Polycomb group proteins:Analysis of function and structure of MK2-Edr Polycomb complexes.

Scholarships:Grant from Hannover Biomedical Research School

Hobbies and other interests:Sports and travelling

First name:Jessica

Last name:Schwermann


Country:Germany


Supervisor:Prof. Dr. M. GaestelPhysiologicalChemistry

EducationCollege/University:2001- 2003: Master of Science in Biotechnology: MaduraiKamaraj University, Madurai., India.1998- 2001: Bachelor of Science ( Chemistry): VanasthaliVidyapith, Rajasthan, India.

Highest degree:Master of Science, Biotechnology

Major Subjects:Biochemistry, Molcular Biology, Immunology, Plant Biotechnology, Animal Biotechnology

Projects/Research:Structural-Functional analysis of cis-acting elements required formRNA stability.

Scientific AchievmentBest poster award on ´Characterization of DNA Gyrasemodulatory activity of Glutamate Racemase from Mycobacteriatuberculosis.Sugopa Sengupta, Meera Shah, V Nagaraja. in ITREID ( transcriptional meeting), 2005.

Scientific Interests and Goals:To get further insights to the proteins involved which areresponsible for mRNA regulation.

Hobbies and other interests:Music, dance, Reading, interest lies in doing science.

PublicationsSugopa Sengupta, Meera Shah, and Valakunja Nagaraja. Glutamate racemasefrom Mycobacterium tuberculosis inhibits DNA gyrase by affecting its DNA-binding. Nucleic Acids Res. 2006 November; 34(19): 5567–5576.

First name:

Meera

Last name:Shah

Date of birth:03. 05. 1980

Country:India


Supervisor:Prof. Dr. H. HoltmannInstitute of PhysiologicalChemistry

EducationCollege/University:1999-2002 B.Sc. Hons. In Chemistry Banaras Hindu University,India2002-2004 M.Sc. Biotechnology, Madurai Kamaraj University,

India

Highest degree:M.Sc. In Biotechnology


Projects/Research:Elucidation of molecular mechanisms of Helicobacter VacA toxin.

Hobbies and other interests:Playing Games (table tennis, cricket), listening to music

First name:Anurag

Last name:Kumar Singh


Country:India

E-mail:[email protected] [email protected]

Supervisor:Prof. Dr. U. SeidlerGastroenterology, Hepatology & Endocrinology

EducationCollege/University: Bsc,Poorvanchal University

Highest degree:M.Sc, JNU, New Delhi


Projects/Research:1. Structural and functional study of Actin binding proteins2. Cloning and expression of recombinant GMCSF in E. coli

Plasmid stability of GM-CSF gene in diff vectorsCenter For Biotechnology JNUSupervisor: KJ Mukherjee Associate Professor JNU

3. Cell BiologyMaintainance of Macrophage,Lymphocyte and Tcell linesMaintaince of entamoeba cell linesWorked with vibrio strains and also some experiments on

proteases

Scientific Interests and Goals: To go into infection biology feild.

Hobbies and other interests:Music

First name:Leena

Last name:Srivastava


Country:India


Supervisor:Dr. E. KorenbaumBiophysical Chemistry

EducationCollege/University:M.Sc Biotechnology from School of Biotechnology, MaduraiKamaraj University

Highest degree:M.Sc Biotechnology

Major Subjects:Molecular Biology, cell biology, biochemistry and biotechnology.

Projects/Research:An approach towards structural determination of Cardamonmosaic virus.To generate SYMV resistance in Soybean crops using siRNAmediated gene silencing.

Scientific Interests and Goals:To do basic research in the field of cell and molecular biology. Post-transcriptional gene regulation.

Hobbies and other interests:Travel and Cricket

First name:Basant Kumar

Last name:Thakur


Country:India


Supervisor:Prof. Dr. H. HoltmannPhysiological Chemistry

EducationCollege/University:1995-2002 Humboldt University Berlin, Medical Faculty

Charitè, Germany

Highest degree:MD (Dr.med.)

Major Subjects:Molecular- and Cell Biology, Differentiation

Projects/Research:Convergence of Wnt- and BMP Morphogen Signaling; CurrentStudies Focus on fluent and blocked Vertebrate CellDifferentiation Cascades; Exemplatory studied in two Model systems: in the endodermal derived Endocrine Gland, Thyroid, and in Haematopoiesis.

Scientific Interests and Goals:Understanding the molecular basis of multicellularity includingdifferentation and proliferation. My goal is to use a dual approachof standard laboratory techniques guided by theoretical models to identify key mechanisms in the regulatory complexity of Morphogens.

Hobbies and other interests:Fine art, Cooking/Sushi, Programming C++ and Perl,, MolluscShell Patterns, History of Physics and Biological Sciences.

Publications:Slominski A, Bortchkareva NV, Botchkarev VA, Chakroborty A, Luger T, Uenalan M, Paus R Biochim Biophys Acta 1998 19; 1448(1): 157-52 Slominski A, Bortchkareva NV, Botchkarev VA, Chakroborty A, Luger T, Uenalan M, Paus R Ann N Y Acad Sci 1999 20;885:448-450Ohnemus U, Uenalan M, Handjiski B, Paus R J Invest Dermatol 2003 122(1): 7-13Ohnemus U, Uenalan M, Conrad F, Handjiski B, Mecklenburg L, NakamuraM, Inzunza J, Gustafsson JA, Paus R Endocrinology 2005;146(3):1214-25.Skokowa J, Cario G, Uenalan M, Schambach A, Germeshausen M, BattmerK, Zeidler C, Lehmann U, Eder M, Baum C, Grosschedl R, Stanulla M, ScherrM, Welte K. Nat Med. 2006;12(10):1191-7

First name:Murat

Last name:Ünalan


Country:Germany


Supervisor:Prof. Dr. K. Welte, Pediatric Hematology & Oncology (formerly Prof. Brabant, Endocrinology)

EducationCollege/University:1997-2001 Huazhong Agricultural University, P.R.China2001-2004 Wuhan Institute of Virology, Chinese Academy of

Sciences

Highest degree:Master of Science

Major Subjects:Tumor immunology

Projects/Research:Identification of a dominant antigen of the murine pancreatic

tumor by SEREX, and characterize the antigen

Scientific Interests and Goals:Tumor research

Hobbies and other interests:Travelling and Movies

First name:Fei

Last name:Zhao


Country:P.R.China


Supervisor:PD. Dr. T.F. GretenGastroenterology, Hepatology& Endocrinology

year 2005

Mathias Christgen

Priyanka Dutta

Ursula Ehmer

Luis Guachalla Gutierez

Lydia Asrat Haile

Harshvardhan

Henoch Hong

Ananta Paine

Amrita Rai

Sumit Rathore

Mathias Rhein

Reena Singh

Inga Sörensen

Ratnesh K. Srivastav

Ujala Srivastava

Kathrin Steinwede

Shazad Nawaz Syed

Dong Wang

Alexander Wolf

Katja Zscheppang

EducationCollege/University:2004-2005: University Kiel, Germany, Institute of Pathology, Clinical Training (PJ).2003-2004: Howard Hughes Medical Institute, Cleveland, U.S.A., Research Scholar in Cancer Genetics.2000-2003: University Kiel, Graduate Student in Medicine. 1998-2000: University Halle, Germany, Undergraduate Student in Medicine.

Highest degree:M.D


Projects/Research:Isolation of characterization of clonogenic breast cancer cells

Awards & Scholarships:2003: Scholarship of the German Academic Exchange Service.2002: Abraham-Buschke-Award of the Charité Berlin.2001: Scholarship of the „Studienstiftung“.1995: Jugend-Forscht-Award in chemistry.

Scientific Interests and Goals:Yo Berra, an American baseball star of the 1950ties, once said: “What gets us into trouble is not what we don‘t know. It‘s what we know for sure that just ain‘t so.“ In my opinion, this pertains to science, too. Hence, it is my goal, that our research on epithelial malignancies truly tackles the nature of cancer.

Hobbies and other interests:Soccer, funk music and cross country skiing.

PublicationsFrom previous work

First name:Matthias

Last name:Christgen


Country:Germany


Supervisors:PD. Dr. U. Lehmann / Prof. Dr. H.H. Kreipe, Pathology

EducationCollege/University:2003-2005 All India Institute for Medical Sciences (AIIMS)



Projects/Research:1. Further characterize the contribution of p53 to cytokine receptor mediated signaling and cellular phenotype in 32Dwt and 32D p53hypo cells. 2. Elucidate cellular components involved in myeloiddifferentiation

Scholarships:1. Awarded by DBT,india for selection in All india combinedM.Sc. biotechnology programe (2003-2005).

Scientific Interests and Goals:My main field of interest is Haematopoesis, I want to study thebiology of the haematopoetic cytokine receptor signalling. I would consider myself to be successful in my ambition if I am inany way able to add to the knowledge that will ultimately help us to understand this fascinating area of biology better.

Hobbies and other interests:Music, books, Movies, literature, etc.

First name:Priyanka

Last name:Dutta


Country:India


Supervisor:Prof. Dr. M. Scherr/ Prof. Dr. M. EderHaematology

EducationCollege/University:1997-2004 Hannover Medical School

Highest degree:MD

Major Subjects:Gastroenterology and hepatology, human genetics, metabolism

Projects/Research:Identification of functional relevant single nucleotide polymor-phisms in drug metabolizing enzymes (UDP-glucuronosyltrans-ferases, UGT). Regulation studies on UGT in a transgenic mouse model

Scientific Interests and Goals:Molecular genetics, impact of genetic polymorphisms on metabolism, regulation of metabolic enzymes.

Hobbies and other interests:Reading, sports, travelling, cooking.

Publications:

Vogel A, Kneip S, Barut A, Ehmer U, Tukey RH, Manns MP, Strassburg CP. Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene. Gastroenterology 2001; 121: 1136-1144

Vogel A, Ockenga J, Ehmer U, Barut A, Kramer FJ, Tukey RH, Manns MP, Strassburg CP. Polymorphisms of the carcinogen detoxifying UDP-glu-curonosyltransferase UGT1A7 in proximal digestive tract cancer. Z. Gastroenterol. 2002, 40(7): 497-502

Ehmer U, Vogel A, Schütte JK, Krone B, Manns MP, Strassburg CP. Variation of hepatic glucuronidation: novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4. Hepatology, 2004; 39(4): 970-977

First name:Ursula

Last name:Ehmer


Country:Germany


Supervisor:PD Dr. C. S. StrassburgGastroenterology, Hepatology & Endocrinology

EducationCollege/University:1998-2003 Universidad Mayor de San Andres. Licenciado in

Biochemistry. La Paz, Bolivia2004-2005 University of Westminster. MSc in Medical

Biotechnology. London, UK

Highest degree:M.Sc. in Medical Biotechnology


Projects/Research:Analysis of the role of oxidative stress and the cell cyclecheckpoint protein g0s2 in organismal ageing.

Scholarships:Full International Scholarship. University of Westminster (2004-2005).

Scientific interests and goals:Ageing, in its broad spectrum of effects, will be the ultimate cause of death of mankind after rather curable diseases in developingcountries are controlled. Since ageing can be considered a multifactorial process, different models to study the decay of life and strategies to contrarest it are being developed. It is probablythe oxidative stress and telomere shortening theories that are themost important and well studied models of ageing, and here I want to establish plausible links between these two multistepprocesses in an in vivo setting with the perspectives to keepprogressing in the field of regenerative medicine.

Hobbies and other interests:Music, brewery, evolution, human relations.

First name:Luis Miguel

Last name:Guachalla Gutierrez


Country:Bolivia


Supervisor:Prof. Dr. K.L. RudolphGastroenterology, Hepatology& Endocrinology

EducationCollege/University:2001-2003 National Institute of Pharmaceutical Education and Research, M.Sc in Pharmacology.

Highest degree:M.Sc. in Pharmacology

Major Subjects:Pharmacology

Projects/Research:T cell based therapies in mouse model of colitis associatedColon cancer

Scientific Interests and Goals:To get further insights in to the molecular causes of diseases.

Hobbies and other interests:Music, Movies, travelling

Publications:Srinivasan K, Viswanad B, Asrat L, Kaul CL, Ramarao P. Combination of high-fat diet fed and low dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening.Pharmacol Res.2005 Oct;52(4):313-20.

First name:Lydia

Last name:Haile


Country:Ethiopia


Supervisor:PD. Dr. T. GretenGastroenterology, Hepatology& Endocrinology

Education2002-2004; Masters in Life Sciences from Jawaharlal Nehru University (JNU), New Delhi.2004-2005; Doctoral student at Indian Institute of Science (IISc), Bangalore.

Highest Degree:M.Sc. in Life Sciences.

Major Subjects:Molecular Cell Biology and Immunology.

Projects/Research:1. Survival of syngenic and xenogenic erythrocytes in mice, Immune functioning and modulation.2. Initiation of replication in single stranded positive sense RNA viruses.

Scholarship:Junior Research Fellowship (JRF-NET) awarded by Council forScientific and Industrial Research (CSIR), India.

Scientific Interests and Goals:I am interested in induction of aging and its molecluar aspects.The main mediators of aging are the immune system and the Nervous system or Brain. In the past time the average age of human being has increased continously and so the incedences of age related disordes like Parkinsons disease and Alzehimers disease that target Brain; have also increased parallely. My work is focused on the induction of aging and ist effect on development and progression of such disorders.

Hobbies and other interests:Music, Cricket, Movies and Poetry.

Name:Harshvardhan

Date of Birth:01.01.1982

Country:India


Supervisor:Prof. Dr. L. K. RudolphGastroenterology, Hepatology & Endocrinology

EducationCollege/University:2000-2005 University of Heidelberg in Biology.2004-2005 Diploma Thesis at the DKFZ (German CancerResearch Center)

Highest degree:Diploma in Biology

Major Subjects:Molecular Biology, Cell Biology, Biochemistry

Projects/Research:Study how HIV-1 affects and impairs the innate immunityfocusing on natural killer cells and dendritic cells; establishing an in vitro model for the interaction of highly purified dendritic cellsand natural killer cells

Scientific Interests and Goals:Immunology and Virology are my main fields of interest.

Hobbies and other interests:Playing piano, Basketball, Christian Literature, Cooking and Eating etc.

First name:Henoch Sangjoon

Last name:Hong


Country:Germany


Supervisor:Prof. Dr. R.E. Schmidt/Dr. H. HeikenClinical Immunology

EducationCollege/University:2002-2004 University of Pune , M.Sc. in Bioinformatics

Highest degree:M.Sc. in Bioinformatics

Major Subjects:Bioinformatics

Projects/Research:Identification of immunotherapeutically targetable peptide

antigens for individualized leukemia treatment .

Scholarships:G.N. Ramchandran Scholarship , awarded by CBT, India (2002-

2004).

Scientific Interests and Goals:My areas of interest are immunology and cancer reseach . As a scientist my dream is to find effective treatments for various

infectious and systematic diseases .

Hobbies and other interests:Painting, movies, music, literature .

First name:Ananta

Last name:Paine


Country:India

E-mail:anantapaine24@@yahoo.com

Supervisor:Prof Dr. B. Eiz Vesper Transfusion Medicine

Education

College/University:1999-2002 Banaras Hindu University, B.Sc. (Hons) in Chemistry2002-2004 Indian Institute of Technology Roorkee, Roorkee M.Sc. in Biotechnology.

Highest degree:M.Sc.


Projects/Research:1. Structure and function of Dynamin and Dynamin Related Proteins.2. Worked as J.R.F at National Centre for Cell Science,Pune India. I was working on project “ Differentiation of mouse embryonic stem cells (mES) into Pancreatic ß cell like clusters (2004-05)3. Project work on “ Studies on acid and salt tolerance of Rhizobial strains isolated from legumes(2004)4. Worked on cloning ,expression and characterization of phosphoenol pyruvate carboxylase,UV survival and thermoluminescence of wild and mutants of Anacystis nidulans (2003).

Scholarships:1. Junior Research Fellowship (JRF) awarded by Council for Scientific and Industrial Research (CSIR), India. Among top 20%2. Qualified Graduate Aptitude Test in Engineering (GATE). All India Rank 563. Received Biotechnology Scholarship for Masters (2002-04),it was sponsored by DBT ,India.

Scientific Interests and Goals:To learn more about Dynamins.

Hobbies and other interests:Music , Dress designing and Roaming

First name:Amrita

Last name:Rai

Date of birth:15-07-1980

Country:India


Supervisor:Prof. D.J.MansteinBiophysical Chemistry

EducationCollege/University:1999-2004 Johann Wolfgang Goethe University of Frankfurt

Highest degree:Diploma of Biochemistry

Major Subjects:Biochemistry, Biophysical Chemistry

Projects/Research:1. Mouse models for neurotrophin receptor- induced leukemia2. Functional analysis of deregulated neurotrophin receptoractivation in leukemia3. Validation of potential therapeutic approaches to treatneurotrophin- induced leukemia

Scholarships:PhD stipendship of the German Jose Carreras LeukemiaFoundation (Deutsche Jose Carreras Leukämie- Stiftung)

Scientific Interests and Goals:My scientific focus is leukemia. We try to understand the basicmechanisms that lead to leukemogenesis through oncogenicderegulation of neurotrophin receptors. The goal is to utililzemouse models for the discovery of new therapeutic approaches to treat human neurotrophin- related leukemia.

Hobbies and other interests:Music(guitar), Aikido, english language, sports

First name:Mathias

Last name:Rhein


Country:Germany


Supervisor:Prof. Dr. C. BaumDr. Z. LiExperimental Hematology

First name:Reena

Last name:Singh


Country:India


Supervisor:Prof. Dr. A. KispertMolecular Biology

EducationCollege/University:2003-2005 Madurai Kamaraj University



Projects/Research:1. Study of expression of pigmentation genes in skin and their

functional role in melanogenesis.2. Cloning of Thaumatin like protein and Chitinase gene in binary

vector and transformation of indica rice variety White Ponni to enhance sheath blight resistance.

Scholarships:1. Fellowship awarded by DBT,india for selection in All india

combined M.Sc. biotechnology programme (2003-2005).2. Junior Research Fellowship (JRF) awarded by Council for

Scientific and Industrial Research (CSIR), India (2005).

Scientific Interests and Goals:My main field of interest is Developmental Biology, I want to

investigate role of T-box genes during heart development.

Hobbies and other interests:Music, dance, love to be in the laps of nature,

EducationCollege/University:2000-2005 University of Applied Sciences Hamburg2003-2004 Biotechnology Research Institue, Montreal, Canada

Highest degree:Diploma in Biotechnology

Major Subjects:Biotechnology:Applied Micro-and Molecular Biology

Projects/Research:1. Expression, Purification and Characterisation of the bacteriocinpediocin PA-1 from Pichia pastoris (BRI, National Research Council of Canada, Montreal)2. Lesion induced plasticity in the spinal cord of adult zebrafish (dDiploma thesis, Center of Molecular Neurobiology Hamburg)3. Analysis of Dll1 function in the vascuar system

Scholarships:1. Karl-Heinz-Ditze Stiftung: full scholarschip for studyingabroad2.Scholarship from DAAD for study expenses in Canada.

Scientific Interests and Goals:My main field of interest is development ofthe vascular system. I want to study genes which are involved in vasculogenesis and angiogenesisy. I would like contribute a small step to thedevelopment of new therapies for vascular diseases in humans.

Hobbies and other interests:Hockey, Fitness, Traveling

Publications:A. Limbourg, M.Ploom, D. Elligsen1, I.Sörensen, T. Ziegelhoefer, A. Gossler, H.Drexler1 and FP. Limbourg. The Notch Ligand Delta-like 1 (Dll1) is Essential for Postnatal Arteriogenesis, Circulation Research, 2007

First name:Inga

Last name:Sörensen


Country:Germany


Supervisor:Prof. Dr. A. GosslerMolecular Biology

EducationCollege/University:2001-2003 Madurai kamaraj University M.Sc in Biotechnology.



Projects/Research:1.Expression, refolding and purification of ßketo acyl ACP reductase an indespansible enzyme of Fatty acid biosynthesisof plasmodium.2.Cloning, subcloning and expression of PKS antibiotics in E.coliexpression system.3. Refolding and purification of C and Z sigma factor of Micobacterium tuberculosis.

Scholarships:1. Awarded by DBT,india for selection in All india combinedM.Sc. biotechnology programe (2001-2003).2. Junior Research Fellowship (JRF) awarded by Council forScientific and Industrial Research (CSIR), India.3. R&D Assistantship from JNCASR, Bangalore, India.4. 40th rank in GATE coducted by Indian institute of technology India in 2003.

Scientific Interests and Goals:My main field of interest is Biochemistry.

Hobbies and other interests:Music, Cricket, Movies, literature, etc.

First name:Ratnesh

Middle nameKumar

Last name:Srivastav


Country:India


Supervisor:Dr. R. Niedenthal/ Prof. Dr. M. GaestelPhysiological Chemistry

EducationCollege/University:1998-2001 Bachelors in Science from University of Lucknow,

Lucknow, India.2001-2003 Masters in Biochemistry from University of Lucknow,

Lucknow, India

Highest degree:M.Sc. in Biochemistry


Projects/Research:Production and characterisation of the Est1 knockout mouse and

the role of Rad9 in replicative senescence.

Scholarships & Awards:Prof. P.S. Krishnan gold medal for securing first position in

mastersCouncil for Scientific and Industrial research(CSIR) and Indian

council of Medical Research (ICMR) fellowship

Scientific Interests and Goals:The elucidation of senescence mechanisms in in vitro and in vivo

systems.

Hobbies and other interests:Music, Reading etc.

First name:Ujala

Last name:Srivastava


Country:India


Supervisor:Prof. Dr. L.K. RudolphGastroenterology, Hepatology& Endocrinology

EducationCollege/University:2000-2005 University Bremen2005 Diploma in Biology (University Bremen)

Highest degree:Dipl. Biology

Major Subjects:Immunology, Microbiology

Projects/Research:Investigation of the role of lysosomal cathepsins in mycobacterialinfections of the lung

Scientific Interests and Goals:To understand the host immune response in engendering protective immunity against bacterial and viral infections and Iam also interested in the strategies of pathogens to evade the immune system. .

Hobbies and other interests:music, guitar, theatre, movies…

First name:Kathrin

Last name:Steinwede


Country:Germany

E-mail:[email protected]@MHH.de

Supervisor:PD Dr. U. MausPneumology

EducationCollege/University:1999-2000 MSc –I Botany (Nagpur University)2000-2002 MSc in Biochemitry (Nagpur University)

Highest degree:MSc (Biochemistry)

Major Subjects:Biochemistry, Biotechnology, Immunology

Projects/Research:1. “Establishment of COS cell Transfection and Erythrocyte Adhesion

Assay for Plasmodium vivax Erythrocyte Binding Protein”.2. “Standardization of AmpRT Assay using HIV-1 genome”3. Understanding the molecular mechanism, genetics and functional

genomics of insecticide resistance Helicoverpa armigera.

Scholarships:1. Indian Council for Medical Research Junior Research Fellowship

(ICMR JRF), July 2003.2. PhD fellowship from German Research Council (GRK-705).

Scientific Interests and Goals:My focus in PhD research is Molecular Immunolgy. I would like to

decipher molecular regulation in autoimmune diseases withspecial emphasis on AIHA so that the knowledge can betranslated into effective therapeutic scheme.Only more research – result oriented, would help invigorate my curiosity and take me to an advanced stage of standpoint.

Hobbies and other interests:Outdoor Sports, Music,Technologies, etc.

First Name:Shahzad Nawaz

Last Name:Syed


Country:India


Supervisor:Prof. Dr. J.E. GessnerClinical Immunology

EducationCollege/University:1997-2002 Peking Union Medical College.

Highest degree:M.D.

Major Subjects:Immunology/Infectious Disease

Projects/Research:Pathogenic roles of keratinocytes in cutaneous lupuserythematosus.

Scholarships:Les Amis de Pasteur,Pasteur Institute of Brussels

Scientific Interests and Goals:Besides interests in Immunology/Infectious disease, I wouldelucidate the role of keratinocytes in the pathophysiology of lupus erythematosus especially the cross presentation of extracellular antigens to MHC-I restricted CD8 T cells.

Hobbies and other interests:Literature,History,Music,Econimy, Philosophy and Linguistic.

Publications:1.Wang D, Liu Baofeng. Malaria Vaccine, p.355-401.Vaccinology. Editor in chief: Zhang Yanling, Science Press of China, Beijng, PR China, 2004

2.Wang D, Mao YH, Wang H. Molecular cloning of P.y. dynamin-like protein PyDyngene and the immunological character of its domains. ACADEMIAE MEDICINAE SINICAE. 2003;25(2):176-80

First name:Dong

Last name:Wang


Country:China


Supervisor:Prof. Dr. M. WittmannDermatology

EducationCollege/University:1999-2004 University Hannoversince 2004 Medical School Hannover

Highest degree:Dipl. Biochemistry

Major Subjects:Biochemistry, Organic Chemistry, Pharmacology

Projects/Research:Analysis of the mechanism by which the yersinia enterocolitica

virulence factor Yop.P inhibits host cell protein kinases

Scientific Interests and Goals:to research the way like the virulence factor Yop.P can inhibit

simultaenously several inflammation pathways

Hobbies and other interests:climbing, hiking, canoeing, travelling by bike, chess, Music

Publications:Tsikas D, Wolf A, Frolich JC. Simplified HPLC method for urinary and circulating

creatinine. Clin Chem. 2004 Jan;50(1):201-3.

First Name:Alexander

Last Name:Wolf


Country:Germany


Supervisor:Prof. Dr. M. KrachtPharmacology

EducationCollege/University:2000-2005 University of Applied Sciences, Senftenberg.



Projects/Research:ErbB4 receptor activation, trafficking, and function in fetal lung type II cells

Scientific Interests and Goals:To get further insights in the mechanisms by which ErbBreceptors regulate processes of fetal lung maturation.

Hobbies and other interests:Meeting with friends, Movies, Reading

Publications:Zscheppang K, Korenbaum E, Bueter W, Ramadurai SM, Nielsen HC, Dammann CE. Pediatr Pulmonol. 2006; 41(12): 1205-12Zscheppang K, Liu W, Volpe MV, Nielsen HC, Dammann CE. Am J Physiol. 2007, submittedBueter W, Dammann O, Zscheppang K, Korenbaum E, Dammann CE. Cytokine. 2007, in pressLiu W, Zscheppang K, Murray S, Nielsen HC, Dammann CE. BiochimBiophys Acta. 2007, submitted

First name:Katja

Last name:Zscheppang


Country:Germany


Supervisor:Dr. C. DammannPediatric Pulmonologyand Neonatology

year 2006

Hengameh Adollahpour

Nora Anderson

Arpita Baisantry

Hari Balaji

Anne Gompf

Maria Gschwandtner

Kshama Gupta

Dhivya Haridass

Niels Heinz

Wolfgang Koestner

Snehlata Kumari

Tobias Mätzig

Manoj Menon

Nidhi Narain

Natalie Naue

Daniel Poehnert

Wilhelm Walter

Kristina Wiege

Xiangyue Zhang

EducationCollege/University:1997-2005 Tehran University of Medical Sciences2005- 2006 research assistant in medical school of Hannover

Highest degree:Medical Doctor

Major Subjects:Molecular Medicine

Projects/ResearchTo study different functions of transcription factor “Gfi1”.

Scientific Interests and Goals:Immunology, Hematology , Oncology and Immunodeficienysyndromes

Hobbies and other interests:Music, travelling, Movies, literature, ….

First name:Hengameh

Last name:Abdollahpour


Country:Iran


Supervisor:Prof. Dr. C. KleinPediatric Hematology &Oncology

EducationCollege/University:1998-2005 Hannover Medical School (MHH), Germany2003-2003 Doctoral student, Department of Anesthesiology,

University of Colorado: Health Sciences Center, Denver, CO, USA.

Highest degree:State Examination (Physician)


Projects/Research:NMR- and MS-based metabonomic approaches to assess biomarkers of liver toxicity.

Scientific Interests and Goals:My specific focus of interest is the connection between aberrations of the cellular metabolism and pathological conditions, including the metabolic response to toxic injury andits role in malignant transformation and maintenance of the malignant phenotype. By working in the research field of metabonomics I hope I will be able to contribute to translation of basic research into advantages for clinical practice.

Hobbies and other interests:Hiking, Literature, Music, Movies

Publications:Anderson, N. and Borlak, J., Drug-induced phospholipidosis FEBS Letters, p.5533-40580 volume 23 (2006).

Anderson, N. Jelena, M., Serkova, N., Time dependent effects of Imatinib on human leukemia cells. Journal of Cancer Research and Oncology, p. 63, volume 130, supplement 1 (2004).

Gottschalk, S., Anderson, N., Hainz, C., Eckhardt, S.G., Serkova, N. Imatinib (STI571) – mediated changes in glucose metabolism in human leukemia BCR-ABL- positive cells. Clinical Cancer Research, p. 6661-6668 volume 10 (2004).

First name:Nora

Last name:Anderson


Country:Germany

E-mail:Nora.andersonweb.de

Supervisor:Prof. Dr. J. BorlakMolecular ToxicologyFraunhofer Institute, ITEM

EducationCollege/University:2001-2004 : B.Sc. (Hons) Microbiolgy, Gargi College, Delhi University,

New Delhi, India.2004-2006 : M.Sc. Biotechnology, AIIMS, New Delhi, India.

Highest degree:M.Sc. in Biotechnology.

Major Subjects:Biotechnology, Molecular Biology, Immunology, Cell Biology

Projects/Research:1. Analyze the functional consequences of the deletion of candidate

genes of the DNA damage pathway on the lifespan, organ homeostasis and stem cell function in telomere dysfunctional mice.

2. Analysis of a telomerase activating compound (GRN TAT0002) in improving liver regeneration.

Awards and Scholarships:1. Junior Research Fellowship (JRF) awarded by Council for Scientific

and Industrial Research (CSIR), 2006, India. 2. Junior Research Fellowship (JRF) awarded by Department of

Biotechnology (DBT-JRF),2006, India.3. Junior Research Fellowship (JRF) awarded by Indian Council of

Medical Research, 2006, India.4. Secured University 2nd rank in B.Sc. (Hons) Microbiolgy (2001-

2004), Delhi University.5. Award for Best Student securing highest aggregate in South Campus

(2001-2004), Delhi University.

Scientific Interests and Goals:Telomere shortening likely influences human ageing by limiting stem cell function, regenerative reserve and organ homeostasis. The checkpoints that are induced by telomere dysfunction on stem cell level are unknown. The characterization of such checkpoints could help to define therapeutic targets aiming to improve regenerative reserve and organ homeostasis during ageing.

Hobbies and other interests:Reading, Listening to music.

First name:Arpita

Last name:Baisantry


Country:India


Supervisor:Prof. Dr. K. L. RudolphGastroenterology,Hepatology& Endocrinology

EducationCollege/University:2001-2003 Madurai Kamaraj University M.Sc in Microbial Gene Technology

Highest degree:M.Sc. in Microbial Gene Technology

Major Subjects:Molecular Biology

Projects/Research:1. Rutin like compound from Punica granatum and itsbioactivities.2. Mechanisms of apotosis induced by phytochemicals in BC-8 cells3. cDNA library screening of AK-5 tumor for a ligand for theactivating NK cell receptor NKRP2

Scholarships:1. Junior Research Fellowship (JRF) awarded by Council forScientific and Industrial Research (CSIR), India.3. GATE scholarship

Scientific Interests and Goals:Translational Research ‘From bench to bedside’(and hopefully from mouse to man) : the ability to rapidly transfer new basic scientific knowledge to biomedical knowledge, in order to generate advanced diagnostic and therapeutic applications, at the same time offering new investigation tools. And in pursuit of that I would like to study common mechanisms in inflammation and cancer.But if someone would ask me to state my research interests in one word, then that would be ‘Immunology’

Hobbies and other interests:Music, dance, history ,literature and sports.

First name:Hari

Last name:Balaji


Country:India

E-mail: [email protected]

Supervisor:Prof. Dr. T. WerfelDermatology

EducationCollege/University:2000-2006 Free University of Berlin


Major Subjects:Genetics, Biochemistry & Molecular Biology, Cell Biology, Immunology

Projects/Research:Investigation of telomere dysfunction-induced environmentalchanges and their influence on hematopoietic stem cell functionand engraftment.

Scientific Interests and Goals:To understand the molecular and cellular basis of ageing and to improve the function of endogenous and also transplanted stem cells in the treatment of regenerative dysfunctions.

Hobbies and other interests:Music, Dancing, Inline Skating, Literature, …

First name:Anne

Last name:Gompf


Country:Germany


Supervisor:Prof. Dr. K.L. RudolphGastroenterology, Hepatology & Endocrinology

EducationCollege/University:2002-2006 IMC University of Applied Sciences Krems, Austria

Medical and Pharmaceutical Biotechnology

Highest degree:Dipl.Ing. (FH)

Major Subjects:Medical Biotechnology

Projects/Research:Investigation of the role of histamine receptor 4 (H4R) in comparison to other histamine receptors in allergic inflammationof the skin

Scientific Interests and Goals:During my PhD studies I want to get more in depth knowledge about the immunology of allergic skin inflammation in general. Particularly I will deal with H4R, which seems to play a role inthe pathogenesis of allergic diseases since it is expressed on cells of the peripheral immune system. Since the expression profile and role of this receptor - in health and disease - have not been adequately investigated and understood till now, the explorationof this receptor is the goal of my future work.

Hobbies and other interests:Having fun, Meeting friends, Reading and some sports

.

First name:Maria

Last name:Gschwandtner


Country:Austria


Supervisor:Prof. Dr. T. Werfel/Dr. R. GutzmerDermatology

EducationCollege/University:M.Sc. Biotechnology [M. Biotech, 2003-2005], Department of

Biotechnology, AIIMS, New Delhi, India.


Major Subjects:Biotechnology [Molecular Biology, Immunology,Cell biology,

Biochemistry, Biostats……]

Projects/Research:Biophysical Chemistry

Scholarships:1. Have been awarded in the All India Biotechnology Quiz

Competition held at the ‘Centre for Biotechnology ‚ JNU, New Delhi, on the ‘National Science Day‘ 2003.

2. Awarded with Junior Research Fellowship (JRF) by Department of Biotectnology (DBT-JRF, 2005) India, and Indian council of Medical Research (ICMR-JRF,2005) ,India.

3. Lecturership by CSIR, India.

Scientific Interests and Goals:My main field of interest is Cell Biology and Biophysics, and

would be fortunate if could get an opportunity to explore and contribute to the better understanding of the field of Neurosciences and neurodegenarative disorders….

Hobbies and other interests:Music, Instrumental Music (Tabla, Piano, Bongo,… .), Sketching,

Painting, Adventure Sports….etc.

First Name:Kshama

Last Name:Gupta


Country:India


Supervisor:Prof. Dr. D. MansteinBiophysical Chemistry

EducationCollege/University:Masters in Biotechnology, University of Madras, 2002-2004.

Highest degree:Masters in Biotechnology

Major Subjects:Biotechnology, Biochemisty

Projects/Research:1. To generate a functional mouse model with a human

immune system and human liver cells for the study of HCV pathogenesis and therapy..

2. To study the functional ability of bone marrow derived stem cells in the repair of endothelial cell damage in liver.

Awards & Scholarships:1. Secured University 7th Rank– Masters Biotechnology 2002-

2004, University of Madras.2. Secured Overall Proficiency First Prize (Best outgoing

student 2004), Alpha Arts and Science College (University of Madras)

3. Junior Research Fellowship (JRF) from Indian Institute of Science, Bangalore, India.

Scientific Interests and Goals:My objective is to take up a challenging research and development position in the fields of stem cell biology, virology and contribute significantly to explore and discover the unseen leading to both human welfare and personal excellence.

Hobbies and other interests:Books, music, chess & cooking

First name:Dhivya

Last name:Haridass


Country:India


Supervisor:Prof. Dr. M. OttGastroenterology, Hepatology& Endocrinology

EducationCollege/University:1998 - 2004 University of Kaiserslautern (Germany)Diploma in Biology in January 2005Title of Thesis: „Analysis of conditional mdr-1 expression in human cells“ Diploma work done at the European Institute for research and development of transplantation strategies (EUFETS, FreseniusBiotech Group)

Major Subjects:Retroviral vectors, haematopoietic stem cell biology

Projects/Research:1) Evaluation and optimisation of „All-in-One“ retroviral vectorsbased on the Tetracycline-regulatory System2) Tet-regulated expression of HoxB4 in haematopoietic (stem) cells3) Tet-regulated expression of chemoresistance genes (MGMT/Mdr-1) in haematopoietic cells

Scientific Interests and Goals:The main interest of my work is to establish an optimized conditional gene expression system which is therapeutically applicable in the field of somatic gene therapy.

Hobbies and other interests:Meeting with friends, music, billard, card-games, soccer,

First name:Niels

Last name:Heinz


Country:Germany


Supervisor:Dr. B. SchiedlmeierProf. Dr. C. Baum Experimental Hematology

EducationUniversity:1997-2003 University Hamburg2000-2003 Medical thesis in the Inst.for Immunology, Hamburg2003-2004 University Lübeck: M.D.-degree2004-2006 Specialist training in neurology, Bad Segeberg

Highest degree:M.D.

Major Subjects:Immunology

Projects/Research:Silencing alloreactivity by leukaemia-specific T cell receptor(TCR) gene transfer

Awards:Second poster-price in the 5th Joint Meeting of theSignal Transduction Society (STS), Weimar 2001

Scientific Interests and Goals:My main field of interest is tumor immunology. In my project TCR gene

transfer into either autologous or allogeneic T cells shall be used to direct T cells specifically against leukemia associated antigens. The potential of genetically engineered T cells to either overcome endogenous tolerance against leukaemia-associated antigens or to break alloreactivity respectively shall be investigated

Hobbies and other interests:Playing the mouthorgan, out door activities

Publications:Krebs C., Koestner, W., Nissen M., Welge V., Parusel I., Malavasi F., Leiter E., H.

Santella R., M., Haag, F., Koch-Nolte F. Flow cytometric and immunoblotassays for cell surface ADP-ribosylation using a monoclonal antibody specificfor ethenoadenosine. Analytical Biochemistry 2003, 314(1):108-15.

Krebs C, Adriouch S, Braasch F, Koestner W, Leiter EH, Seman M, Lund FE, Oppenheimer N, Haag F, Koch-Nolte F. CD38 controls ADP-ribosyltransferase-2-catalyzed ADP-ribosylation of T cell surface proteins. J Immunol. 2005;174(6):3298-305.

First name:Wolfgang

Last name:Koestner


Country:Germany


Supervisor:PD Dr. M. SauerPediatrics

EducationCollege/University:2004-2006 University of Pune, Pune MSc in Biotechnology.



Projects/Research:Clinical Immunology, C5a pathway

Scholarships:1. DBT,Govt. of India Scholarship for All india combined M.Sc. biotechnology programe (2004-2006).2. Junior Research Fellowship (JRF) awarded by Council forScientific and Industrial Research (CSIR), India, 2006.3. Junior Research Fellowship by DBT, Govt. of India, 2006.

Scientific Interests and Goals:My main field of interest is Immunology, which has clinicalapplication too!

Hobbies and other interests:Music, Net Surfing, literature, etc.

First name:Snehlata

Last name:Kumari


Country:India



EducationCollege/University:2000-2005 Ruhr-University Bochum, Germany


Major Subjects:Molecular Biology and Virology

Projects/Research:1. Comparative studies of malignant transformation events caused

by gene transfer into hematopoietic stem cells by γ-retro andlentiviral vectors.

2. Identification of stem cell expanding genes by insertionalmutagenesis.

3. Improvement of gene transfer vectors and methods to increasegene therapy savety.

Scholarships:1. Awarded by „Studienstiftung des deutschen Volkes“ for

undergraduate studies (2003 – 2005)2. Awarded by „Studienstiftung des deutschen Volkes“ for

graduate studies (2006)

Scientific Interests and Goals:Retrovirus mediated gene therapy is one of the most interesting topics in science. It combines interdisciplinary research dealing with virology, signaling, imaging and all kinds of molecular biology at the boarder between life science and the clinics.One of my greatest scientific goals is to help make gene therapymore applicable and even saver than it is today, so that genetictreatment can become a standard therapy one day.

Hobbies and other interests:Music, Movies, Cocking, etc.

First name:Tobias

Last name:Mätzig


Country:Germany


Supervisor:Prof. Dr. C. BaumExperimental Hematology

EducationCollege/University:2004-2006 Madurai Kamaraj University, M.Sc. (MGT). 2001-2004 Presidency College, Bangalore University, B.Sc. in Biotechnology.

Highest degree:M.Sc. in Microbial Gene Technology

Major Subjects:Microbial Gene Technology

Projects/Research:Biochemistry

Scholarships:1. Junior Research Fellowship (JRF) awarded by Council forScientific and Industrial Research (CSIR), India.2. Bharat Petroleum Scholarship (2004) for higher studiesawarded by Bharat Petroleum Corporation, India.

Scientific Interests and Goals:My main field of interest is Biochemistry. I am interested in understanding the molecular basis of life. I have always tried and will always try to bring the branches of chemistry and biology together and see life as a set of co ordinated chemical events. I would like to add on to this basic understanding, which can makethings simple and life easier

Hobbies and other interests:Music, Reading, sketching etc.

First name:Manoj

Last name:BalakrishnaMenon


Country:India


Supervisor:Prof. Dr. M. GaestelPhysiological Chemistry

EducationCollege/University:2001-2004 : B.Sc. (Hons) Microbiology, University of Delhi,

India.2004-2006 : M.Sc. Biotechnology, A.I.I.M.S, New Delhi, India.

Highest degree:Masters in Biotechnology

Major Subjects:Biotechnology, Molecular Biology, Immunology and Cell biology

Projects/Research:•To study the effect of human MSC on engraftment and repopulation of cord blood derived haematopoietic stem cells in sublethaly irradiated Balb/C Rag2/yc(-/-) mice.•To study in vitro the differentiation of hMSC to hepatocytes.

Scholarships/Awards:Awarded Junior Research Fellowship by Indian Council of Medical Research (I.C.M.R) in Jul 2006Awarded lectureship in NET-CSIR Examination held in Dec 2005Awarded Junior Research Fellowship by Indian council for Agricultural Research in 2004.Received the award for “Best student in microbial World” in graduation.

Scientific Interests and Goals:My main field of interest is Stem Cell Biology.The role of the stem cells in giving rise to different cell types and entire organs for tissue repair and transplants, is what fascinates me the most. I welcome the challenge of serving global community by participating in such a dynamic and challenging field as that ofstem cell liver transplantation. I would consider myself flourishing in my endeavors if I am able to make a sound and humble contribution towards the betterment of patients suffering from liver injuries and failures.

Hobbies and other interests:Traveling to different places,listening to music, dancing and watching movies.

Publications:V. Baniasadi, N. Narain, R. Goswami & S.N. Das. Promoter region –318 C/T and –1661 A/G CTLA-4 Single nucleotide polymorphisms and type 1 diabetes in North Indians. Tissue antigens 2006 : 67 : 383-389.

First name:Nidhi

Last name:Narain


Country:India

E-mail:nidhinarain@@yahoo.com

Supervisor:Prof. Dr. M. OttGastroenterolgy, Hepatology & Endocrinology

Education2001-2006 University of Hanover, Germany

Highest degree:Diploma‘ in Biology

Subjects:Cellular and Developmental BiologyBiochemistryImmunology

Projects/Research:1. Membrane association and sorting of splicing variants and

artificially generated mutants of intestinal lactase2. Protein – Protein and Protein-DNA interactions at the DNA

replication fork of E.coli

Scientific Interests and Goals:It’s interesting how proteins work, so I am fortunate that my PhD project involves comparison of protein structure and function.

Hobbies and other interests:English Literature, Travel, Botany

First name:Natalie

Last name:Naue


Country:Germany


Supervisor:Dr. U. CurthBiophysical Chemistry

EducationCollege/University:2000-2006 Medizinische Hochschule Hannover, Medicine

Highest degree:MD

Major Subjects:Transplantation Medicine

Projects/Research:1. In vitro studies of the natural killer cell complex: intra- and intercellular response to ligands2. In vivo experiments: the role of the natural killer cell complex in transplantation

Scientific Interests and Goals:Transplantation immunology is of most interest to me. Although there are great progresses done on this field of research a lot of pathomechanisms leading to graft loss or acceptance are still not known yet. It is my effort to gain a deeper insight of those mechanisms and to transfer this knowledge to clinical practice.

Hobbies and other interests:music, sports, movies, literature, etc.

Publications:Koch M., Mengel M., Poehnert D., Nashan B.: Effects of Everolimus on cellular and humoral immune processes leading to CAN in a rat model with sensitized recipients; accepted in Transplantation

First name:Poehnert

Last name:Daniel


Country:Germany


Supervisor:Dr. M. Koch/ PD Dr. R. LückVisceral Surgery

Education University:2001-2006 Universität Hannover

Highest degree:Diplom-Biologe

Major Subjects:Biophysics

Projects/Research:Motor Mechanics of Cytoplasmic Dynein

Scientific Interests and Goals:Molecular motors like cytoplasmic dynein are the heart of almost all biological transport processes, whether in organized structures, such as in muscles and axonemes or acting in isolation to move single sub-micron-sized cargo. There are many diseases linked to mutations in molecular motors and understanding of the molecular interaction during the force-generating cycle is still at an elementary stage. That is why I will try to find out more about cytoplasmic dynein's motor mechanics.

Hobbies and other interests:Music and instruments, canoeing, literature,photos

First name:Walter

Last name:Wilhelm


Country:Austria


Supervisor:PD Dr. W. SteffenMolecular and Cell Physiology

EducationCollege/University:2000-2005 Carl von Ossietzky University, Oldenburg

Highest degree:Dipl. Biology

Major Subjects:Molecular Biology

Projects/Research:1. Mechanisms of cell and isotype specific Gαi dependent

signaling pathways in immune effector cells2. Inhibition of the NFκB repressing factor (NRF) mRNA by

RNA-Interference3. Age determination of Orix euplectes by the length of

telomeres

Scholarships:GRK 705 II „ Characterization of pathophysiological

animal models“, Medical School Hanover

Scientific Interests and Goals:My main field of interest is gene regulation and

signaltransduction in the immune system. I would like to understand some of the complex mechanism which providethe basis for the diverse organisation of the immune system.

Hobbies and other interests:Scuba Diving, Photography, Motorbike

First name:Kristina

Last name:Wiege


Country:Germany



EducationCollege/University:2001-2004 Peking Union Medical College, P.R. China

Highest degree:M.Sc. In Molecular Immunology

Major Subjects:Immunology, Medicine

Projects/Research:1.Identification of alternative spliced isoforms of hIL-23R2.The role of IFN gamma on tumor stroma cells3.The role of stroma cells (including mesenchymal stem cells) in the

functional organization of lymphoid organs

Scholarships:Medical Education Scholarship of The United Laboratories (Hongkong) in the Medical Universities of mainland China, Golden Prize (1998-1999)

Scientific interests and goals:Immune system is quite fancy, finding something novel and interesting in basic immunological areas is my long term goal. My scientific goal during Ph.D study is to identify something new on stroma cells of lymphoid organs, e.g. what’s the special subset marker, how they function on the interactions of different immune cells especially their migration during the development of lymphoid organs and immune reactions. Besides this I also quite like transcriptional and epigenetics control of lymphocytes, in their functional differentiation and memory, etc.

Hobbies and other interests:Hiking, Music, Reading

Publication List:Xiangyue Zhang, Shuhui Wang. Progress in the study of IL-23 and IL-23 receptor,BasicMedical Sciences and Clinics,August, 2004; 24(4), p457-461.

Xiangyue Zhang, Zhiguang Li, Zhihai Qin. Cancer Immunosurveillance or not? (New view), Progress in biochemistry and biophysics, November,

2005;32(11), p1093-1098.

Xiangyue Zhang, Li Liu, et al. Alternative Splicing of Human IL-23 Receptor Gene Generates Multiple Isoforms in Selected Tumor Cell Lines. Immunogenetics, 2006 Jan;57(12):934-43

First name:Xiangyue

Last name:Zhang


Country:P. R. China


Supervisor:Prof. Dr. R. FörsterImmunology

Faculty Jürgen Alves Andreas Lengeling (GBF)

Christopher Baum Zhixiong Li

Armin Braun (Fraunhofer Inst.itut) Robert Lindner

Jan Buer (GBF) Nisar Peter Malek

Olaf Dammann Dietmar Manstein

Matthias Eder Ulrich Maus

Britta Eiz-Vesper Fritz Melchers (MPI, Berlin)

Reinhold Förster Martin Messerle

Matthias Gaestel Nils v. Neuhoff

Harald Genth Heiner Niemann (TiHo, Mariensee)

Engelbert Gessner Francoise Routier

Achim Gossler Lenhard Rudolph

David Groneberg Michaela Scherr

Matthias Gunzer (GBF) Bernhard Schieffer

Carlos Alberto Guzmann (GBF) Brigitte Schlegelberger

Hermann Haller Reinhold Ernst Schmidt

Hansjörg Hauser (GBF) Jörg Schmidtke

Hans Heiken Thomas F. Schulz

Denise Hilfiker Reinhard Schwinzer

Helmut Holtmann Ursula Seidler

Peter Horn Axel Seltsam

Roland Jacobs Beate Sodeik

Elmar Jaeckel Manfred Stuhrmann-Spangenberg

Christine Josenhans Burkhard Tümmler

Ingo Just Ernst Ungewickell

Andreas Kispert Claus Urbanke

Christoph Klein Jürgen Wehland (GBF)

Andreas Klos Siegfried Weiss (GBF)

Hannes Klump Eva Weissinger

Alexey Kotlyarov Karl H. Welte

Hans Kreipe Thomas Werfel

Norbert Krug (Fraunhofer Institut) Miriam Wittmann

Ulrich Lehmann Anna M. Wobus (IPK Gatersleben)

Department and function:Professor, Biophysical Chemistry

Education:1975 – 1981 University of Hannover, Biochemistry1981 – 1984 PhD thesis

Positions:1984 – 1990 Postdoc Hannover Medical School1990 – 1995 PD Hannover Medical School1995 - Prof. Hannover Medical School

Major research interests:Protein design using different model systems:• Restriction endonuclease EcoRI• IS1 Transposase• Helikase I• DynaminCircular Dichroism Spectroscopy

Selected Publications:Kalthoff C, Alves J, Urbanke C, Knorr R, Ungewickell EJ. J Biol Chem 2002, 277: 8209-16.Scheele U, Alves J, Frank R, Duwel M, Kalthoff C, Ungewickell E. J Biol Chem. 2003; 278(28):25357-68.Fritsche P, Alves J. Biol Chem. 2004; 385(10):975-85Wierstra I, Alves J. Biochem Biophys Res Commun. 2006 Sep 15;348(1):99-108.Wierstra I, Alves J. Biol Chem. 2006 Jul;387(7):949-62. Wierstra I, Alves J. Biol Chem. 2006 Jul;387(7):963-76.Wierstra I, Alves J. FEBS J. 2006 Oct;273(20):4645-67Wierstra I, Alves J. Biochem Biophys Res Commun. 2007;352(1):61-8.

First name:Jürgen

Last name:Alves

Acad. Title:Prof. Dr. rer. nat.

Address:OE 4350Hannover Medical School

Phone and e-mail:++49-0511-532 [email protected]

Further information:http://www.mh-hannover.de/institute/bpc

Department and function:Professor, Experimental Hematology

Education:1981-1982 Philosophy1982-1989 Medicine

Positions:1989-1991 Research Clinics, Borstel b. Bad Oldesloe1991-1992 Toxicology, Univ. of Hamburg1993-1999 Heinrich-Pette-Institute Hamburg 2000 University Hospital Eppendorf, Hamburg2000 - MHH, Dept. Hematology and Oncology2002 - Cincinnati Children‘s Hospital Adjunct Position2006 - Head of Experimental Hematology

Major research interests:Cell Therapy, Gene Transfer and TherapyRetroviruses, Gene expressionStem Cell BiologyBiology of cell selection and clonal evolutionOncogenesis

Selected Publications:Baum C, et al. Mol Ther. 2004; 9(1):5-13.Werner M, et al. Gene Ther. 2004; 11(12):992-1000Klein C, Baum C. Hematol J. 2004;5(2):103-11Williams D, Baum C Nature. 2004; 429(6988):129Frank O, et al. Blood. 2004; 104(12):3543-9.Kraunus J, et al. Gene Ther. 2004; 11(21):1568-78.Galla M, et al. Mol Cell. 2004; 16(2):309-15. von Kalle C, et al. Semin Hematol. 2004; 41(4):303-18.Modlich U, et al. Blood. 2005; 105(11):4235-46.Kustikova O, et al. Science. 2005; 308(5725):1171-4.Klump H, et al. Ann N Y Acad Sci. 2005; 1044:6-15.Schambach A, et al. Mol Ther. 2006 Feb;13(2):391-400.Schambach A, et al. Gene Ther. 2006; Apr;13(7):641-5Schambach A, et al. Gene Ther. 2006 Jul;13(13):1037-47Schambach A, et al. Exp Hematol. 2006 May;34(5):588-92.Modlich U, et al. Blood. 2006 Oct 15;108(8):2545-53.Kraunus J, et al. J Biol Chem. 2006 Dec 8;281(49):37381-90Kustikova OS, et al. Blood. 2006 Nov 21; E pub

First name:Christopher

Last name:Baum

Acad. Title:Prof. Dr. med.Prof. of Pediatrics



Further information:http://www99.mh-hannover.de/kliniken/zellth/

Department and function:Head of Immunology and Allergology, Fraunhofer Institute of Toxicology and Experimental Medicine

Education:1998 PhD in Immunology, Humboldt-University

Berlin

Positions:1999-2001 Scientific Assistant (“post doc”), Prof. Dr. Renz,

Department of Clinical Chemistry, Philipps University Marburg, Germany

2001- Head of Immunology and Allergology, FraunhoferInstitute of Toxicology and Experimental Medicine

Major research interests:Neuro-immun Interaction in asthmaAnimal models of asthmaLung infection modelsImmunotoxicology

Selected Publications:C. Nassenstein, A. Braun, V.J. Erpenbeck, M. Lommatzsch, et al. J Exp Med. 2003; 198:455-467.A. Braun, M. Lommatzsch, U. Neuhaus-Steinmetz, D. Quarcoo, H. Renz. Br J Pharmacol. 2004;141:431-440H. Weigt, P.F. Muhlradt, M. Larbig, N. Krug, A. Braun. J Immunol. 2004; 172(10):6080-6.U. Forssmann, I. Hartung, R. Bälder, S.E. Escher, et al. J Immunol. 2004; 173(5):3456-66..R. Bälder, B. Fuchs, W. Bautsch, J. Zwirner, et al. J. Immunol. 2005; 174(2):783-9.Schulte-Herbruggen O, Nassenstein C, Lommatzsch M, Quarcoo D, Renz H, Braun A. J Neuroimmunol. 2005;160(1-2):204-9Weigt H, Nassenstein C, Tschernig T, Muhlradt PF, Krug N, Braun A. Am J RespirCrit Care Med. 2005;172(5):566-72.Lommatzsch M, Quarcoo D, Schulte-Herbruggen O, Weber H, Virchow JC, Renz H, Braun A. Int J Dev Neurosci. 2005;23(6):495-500.Nassenstein C, Schulte-Herbruggen O, Renz H, Braun A. Eur J Pharmacol. 2006; 533(1-3):195-206. Nassenstein C, Dawbarn D, Pollock K, Allen SJ, Erpenbeck VJ, Spies E, Krug N, Braun A. J Allergy Clin Immunol. 2006;118(3):597-605

First name:Armin

Last name:Braun

Acad. Title:PD Dr.

Address:Nikolai-Fuchs-Str. 130625 Hannover

Phone and e-mail:+49 511 5350 [email protected]

Further information:www.item.fraunhofer.de

Department and function:Professor, Mucosal Immunity, HZI Braunschweig

Education:1987-1994 Medicine in Hannover and New York, 1995 Approbation, Doctor of Medicine, 2001 Habilitation in Immunology,

Positions:1998-present Head of Mucosal Immunity (HZI), 1998-present Institute of Medical Microbiology (MHH), 1996-1998 DFG-Fellowship in Immunology, Hôpital Necker-

Enfants Malades, Paris, France,1995-1996 Resident in Internal Medicine, Department of

Hematology and Oncology (MHH),

Major research interests:My current work on mucosal immunity concentrates on functional genomics of regulatory T cells in transgenic mouse models and patients with autoimmunity and inflammation. Other interests are Host-Pathogen-Crosstalk and Molecular Diagnostics.

Selected Publications:Bruder D, Westendorf AM, Geffers R, Gruber AD, et al. Am J Respir Crit Care Med. 2004; 170(11):1145-52Westendorf AM, Templin M, Geffers R, Deppenmeier S, et al. Gut. 2005; 54:60-9.Ma HW, Kumar B, Ditges U, Gunzer F, Buer J, Zeng AP. Nucleic Acids Res. 2004; 32(22):6643-9.Juhas M, Wiehlmann L, Salunkhe P, Lauber J, Buer J, Tummler B. FEMS MicrobiolLett. 2005; 242(2):287-95Rharbaoui F, Bruder D, Vidakovic M, Ebensen T, Buer J, Guzman CA. J Immunol. 2005; 174(3):1317-24Bruder D, Westendorf AM, Hansen W, Prettin S, Gruber AD, Qian Y, von BoehmerH, Mahnke K, Buer J. Diabetes. 2005;54(12):3395-401.Hansen W, Loser K, Westendorf AM, Bruder D, Pfoertner S, Siewert C, Huehn J, Beissert S, Buer J. J Immunol. 2006;177(1):209-15.Franzke A, Hunger JK, Dittmar KE, Ganser A, Buer J. Ann Hematol. 2006;85(11):747-58. Westendorf AM, Fleissner D, Deppenmeier S, Gruber AD, Bruder D, Hansen W, Liblau R, Buer J.Gastroenterology. 2006;131(2):510-24.Franzke A, Koenecke C, Geffers R, Piao W, Hunger JK, Ganser A, Buer J. TumourBiol. 2006;27(6):329-33.Westendorf AM, Bruder D, Hansen W, Buer J. Ann N Y Acad Sci. 2006;1072:401-6.

First name:Jan

Last name:Buer

Acad. Title:Prof. Dr. med.

Address:HZIMascheroder Weg 138124 Braunschweig

Phone and e-mail:[email protected]

Further information:www.helmholtz-hzi.de

Department and function:Head, Perinatal Infectious Disease Epidemiology UnitObstetrics, Prenatal Medicine, and General GynecologyPediatric Pulmonology and Neonatology

Education:1981-83 Linguistics, U of Hamburg, 1983-90 Medicine, Med U of Lübeck and U of Hamburg,

Epidemiology,1996-97 Harvard School of Public Health,

Positions:1991-95 Post-Doc, Pediatrics, U of Hamburg1995-97 Post-Doc, Neuroepidemiology, Children‘s Hospital,

Boston,1997-2000 Instructor in Neurology, Harvard Med School,since 2000 Assistant Professor in Neurology, Harvard Med School, since 2002 Professor of Perinatal Infectiology, Hannover Med.

School

Major research interests:Epidemiologic research on the role of infection and inflammation in theetiology and pathogenesis of brain white matter damage in pretermnewborns

Selected Publications:Dammann O, Leviton A. Ann Neurol. 2004;55(2):158-161.Dammann O, Allred EN, Van Marter LJ, Dammann CE, Leviton A. Pediatr Res. 2004; 55(2):319-325.Leviton A, Dammann O. Pediatr Res. 2004; 55(4):541-5Losch H, Dammann O. J Child Neurol. 2004; 19(5):318-22.Dammann O, Allred EN, Leviton A, Shen-Schwarz S, Heller D, Genest DR, Collins MH. Placenta. 2004; 25(10):788-96.Dammann O, Bartels DB, Berner R. Pediatr Infect Dis J. 2004;23(10):978-9Bartels DB, Kreienbrock L, Dammann O, Wenzlaff P, Poets CF. Arch Dis Child FetalNeonatal Ed. 2005; 90(1):F53-9.Leviton A, Blair E, Dammann O, Allred E. J Pediatr. 2005; 146(1):123-7.Dammann O, Leviton A, Gappa M, Dammann CE. BJOG. 2005 Mar;112 Suppl 1:4-9.Dammann O, Hori A, Szentiks C, Hewicker-Trautwein M. Dev Med Child Neurol. 2006; 48(4):290-3.Dammann O, Leviton A. Semin Fetal Neonatal Med. 2006 Oct;11(5):363-8.Dammann O, Leviton A. N Engl J Med. 2006 Aug 17;355(7):727-9.Dordelmann M, Kerk J, Dressler F, Brinkhaus MJ, Bartels DB, Dammann CE, Dork T, Dammann O. Neuropediatrics. 2006 Jun;37(3):130-6.

First name:Olaf

Last name:Dammann

Acad. Title:Prof. Dr.med., M.Sc.

Address:OE6415Hannover Medical School

Phone and e-mail:++49-511- 532 [email protected]

Further information:http://www.mh-hannover.de/forschung/perinatalinfektiologie/index.htm

Department and function:Professor, Hematology/Oncology unit; Consultant Bone marrow transplantation

Education:1982-89 Study of Medicine, Homburg/S and

Frankfurt/M1990 Doctoral thesis1989-91 Research assistant and fellow Int. Med.1991-93 Research fellow Dana Farber Cancer Inst., Boston1993-2000 Research fellow Int. Med. Frankfurt + MHHSince 2001 Habilitation, consultant Int. Medicine

Positions:1991-1993 Dana Farber Cancer Institute, Boston1993-1996 Johann Wolfgang v.Goethe University

FrankfurtSince 1996 MHH

Major research interests:Signal transduction by cytokine receptors in myeloid cellsModels for myeloproliferative disorders and acuteleukemiaLentiviral gene transferRNA interference

Selected Publications:Scherr M, Battmer K, Winkler T, Heidenreich O, Ganser A, Eder M.. Blood 2003, 101:1566Scherr M, Morgan MA, Eder M. Curr Med.Chem 2003, 10: 245Tiede A, Eder M, von Depka M, Battmer K, Luther S, et al. Gene Ther. 2003; 10(22):1917-25. Scherr M, Steinmann D, Eder M. Ann Hematol. 2004; 83(1):1-8.Scherr M, Battmer K, Dallmann I, Ganser A, Eder M. Oligonucleotides. 2003; 13(5):353-63.Scherr M, Eder M. Curr Opin Mol Ther. 2004; 6(2):129-35Scherr M, Battmer K, Schultheis B, Ganser A, Eder M. Gene Ther. 2005; 12:12-21.Eder M, Scherr M. N Engl J Med. 2005; 352(23):2446-8.Scherr M, Chaturvedi A, Battmer K, Dallmann I, Schultheis B, Ganser A, Eder M. Blood. 2006;107(8):3279-87.Venturini L, Eder M, Scherr M. J Biomed Biotechnol. 2006;2006(4):87340.Venturini L, Battmer K, Castoldi M, Schultheis B, Hochhaus A, Muckenthaler MU, Ganser A, Eder M, Scherr M. Blood. 2007 Feb 6; [Epub ahead of print]

First name:Matthias

Last name:Eder




Further information:http://www.mh-hannover.de/kliniken/haemonko/index.htm

Department and function:Professor, Institute for Transfusion Medicine

Education:1988 – 1993 Biology, University Greifswald1993 – 1996 PhD, Virology, MHH2003 W1-Professor for Immunogenetics, Institute for

Transfusion Medicine, MHH

Positions:1996-1999 Research Group Leader at the German Red Cross

Institute, Springe1999-2003 Research Group Leader, Institute for Transfusion

Medicine, MHH2003-recent W1-Professor for Immunogenetics, Institute for

Transfusion Medicine, MHH

Major research interests:• Minor histocompatibility antigens involved in GvL and GvHD• Antigen-specific cytotoxic T cells• Cell therapy• Expression of recombinant HLAs and proteins• Peptide sequencing

Selected Publications:Elsner HA, Bernard G, Eiz-Vesper B, de Matteis M, Bernard A, Blasczyk R. Tissue

Antigens. 2002; 59(2):139-141.Khattab B, Eiz-Vesper B, Ganser A, Hertenstein B, Blasczyk R. Ann Hematol 2004:

83: 107-113.Eiz-Vesper B, Seltsam A, Blasczyk R. Transfusion 2005; 45 (6): 960-968.Bade-Doeding C, Elsner HA, Eiz-Vesper B, Seltsam A, Holtkamp U, Blasczyk R.

Immunogenetics 2004; 56: 83 - 88. Bade-Doeding C, Elsner HA, Eiz-Vesper B, Seltsam A, Holtkamp U, Blasczyk R.

Immunogenetics 2005; 56: 769-772.Eiz-Vesper B, Horn PA, Daubert C, Khattab B, Blasczyk R. Transfusion 2006;

46(7):1210-20.Bade-Doeding C, Deluca DS, Seltsam A, Blasczyk R, Eiz-Vesper B. Immunogenetics

2007 Feb 10; [Epub ahead of print]

First name:Britta

Last name:Eiz-Vesper


Address:OE 8355Institute for Transfusion MedicineHannover Medical School

Phone and e-mail:++49- 511- 532 [email protected]

Further information:www.mh-hannover.de/institute/transfusion

Department and function:Director, Immunology

Education:1981 Abitur, Gymnasium Pegnitz1988 DVM, Munich, Veterinary Faculty1988 - 1991 Ph.D. Thesis

Positions:1991-93 Postdoc, Insitute of Biochemistry, University of Munich1994-00 Research Associate, Max-Delbruck-Center for

Molecular Medicine, Berlin2000-01 Associate Professor for Experimental Surgery and

Immunology, University of Erlangen2001 – Director and Head, Institute of Imunology, Professor for

Immunology

Major research interests:Chemokines and chemokine receptors, role in lymphoid organorganogenesis and organization, development of immunology memory,cell migration, tumor metastasis

Selected Publications:Pabst O, Ohl L, Wendland M, Wurbel MA, Kremmer E, Malissen B, Forster R J Exp

Med. 2004; 199(3):411-6Pabst O, Herbrand H, Bernhardt G, Forster R. Curr Opin Immunol. 2004; 16:394-9.Misslitz A, Pabst O, Hintzen G, Ohl L, et al. J Exp Med. 2004; 200(4):481-91Ohl L, Mohaupt M, Czeloth N, Hintzen G, et al. Immunity. 2004; 21(2):279-88.Pabst O, Herbrand H, Worbs T, Friedrichsen M, et al. Eur J Immunol. 2005; 35:98-

107.Gunther K, Leier J, Henning G, Dimmler A, Weissbach R, Hohenberger W, Forster

R. Int J Cancer. 2005 Sep 20;116(5):726-33Hardtke S, Ohl L, Forster R. Blood. 2005 Sep 15;106(6):1924-31.Pabst O, Peters T, Czeloth N, Bernhardt G, Scharffetter-Kochanek K, Forster R. J

Immunol. 2005 Jun 15;174(12):7492-5.Czeloth N, Bernhardt G, Hofmann F, Genth H, Forster R. J Immunol. 2005;

175(5):2960-7.Pabst O, Herbrand H, Willenzon S, Worbs T, Schippers A, Muller W, Bernhardt G,

Forster R. J Immunol. 2006; 176(3):1474-80.Pabst O, Herbrand H, Friedrichsen M, Velaga S, Dorsch M, Berhardt G, Worbs T, Macpherson AJ, Forster R. J Immunol. 2006 Nov 15;177(10):6824-32.Hintzen G, Ohl L, del Rio ML, Rodriguez-Barbosa JI, Pabst O, Kocks JR, Krege J, Hardtke S, Forster R. J Immunol. 2006 Nov 15;177(10):7346-54.Berberich S, Forster R, Pabst O. Blood. 2007 Feb 8; [Epub ahead of print] Davalos-Misslitz AC, Rieckenberg J, Willenzon S, Worbs T, Kremmer E, Bernhardt G, Forster R. Eur J Immunol. 2007 Feb 16; [Epub ahead of print]

First name:Reinhold

Last name:Förster

Acad. Title:Prof. Dr. med. vet



Department and function:Director, Biochemistry (Physiological Chemistry)

Education:1983 PhD in Biology (Biophysics), Humboldt-University

Berlin1993 Habilitation in Biochemistry, Free University Berlin

Positions:1991-1995: Junior Research Group Leader at the Max-Delbrück-

Centrum for Molecular Medicine (MDC), Berlin-Buch1995-1997: Heisenberg-Fellow of the German Research Council

(DFG), Guest Research Group Leader at the MDC,Berlin-Buch

1997-2000: Professor of Molecular Genetics; Innovationskolleg"Zellspezialisierung" of the Martin-Luther-UniversityHalle-Wittenberg

2001-recent: Chair and Head of Institute of Biochemistry/ Physiological Chemistry of Hannover Medical School

Major research interests:Analysis of mechanisms of stress-dependent signal transductionNucleo-cytoplasmic signallingRegulation of gene expression by protein phosphorylation at the post-transcriptional level

Selected Publications:Neininger A., Thielemann H, Gaestel M. EMBO Rep. 2001; 2: 703-708.Neininger A., Kontoyiannis D., Kotlyarov A., Winzen R., Eckert R., et al. J. Biol. Chem. 2002; 277: 3065-3068.Kotlyarov A., Yannoni Y., Fritz S., Laaß K., Telliez J.-B., et al. Mol. Cell. Biol. 2002; 22: 4827-4835.Shi Y, Kotlyarov A, Laabeta K, Gruber AD, Butt E, et al. Mol Cell Biol. 2003; 23(21): 7732-7741.Schumacher S, Laass K, Kant S, Shi Y, Visel A, Gruber AD, Kotlyarov A, Gaestel M EMBO J. 2004; 23(24):4770-4779Gaestel M. Nat Rev Mol Cell Biol. 2006; 7(2):120-30.Hitti E, Iakovleva T, Brook M, Deppenmeier S, Gruber AD, Radzioch D, Clark AR, Blackshear PJ, Kotlyarov A, Gaestel M. Mol Cell Biol. 2006;26(6):2399-407.Vertii A, Hakim C, Kotlyarov A, Gaestel M. J Biol Chem. 2006;281(37):26966-75Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, Gaestel M. J Biol Chem. 2006;281(46):35511-9.

First name:Matthias

Last name:Gaestel

Acad. Title:Prof. Dr.



Further information:www.mh-hannover.de/institute/biochemie

Department and function:Group leader, Department of Toxicology

Education:1998-95 Chemistry, Technical University of Darmstadt,

Germany 1995-2000 PhD in Chemistry, Albert-Ludwigs-Universität

Freiburg

Positions:2000-recent: Group leader, Institute of Toxicology/

Hannover Medical School

Major research interests:Mode of action of bacterial protein toxinsSignal transduction pathways governed by Rho and Ras

Selected Publications:Genth, H., J. Selzer, C. Busch, J. Dumbach, F. Hofmann, K. Aktories, I. Just.. Infection and Immunity. 2000; 68: 1094-1101Genth, H., R. Gerhard, A. Maeda, M. Amano, K. Kaibuchi, K. Aktories, I. Just.. Journal of Biological Chemistry. 2003; 278:28523-28527.Gerhard,R., H. Tatge, H. Genth, T. Thum, J. Borlak, G. Fritz, I. Just.. Journal of Biological Chemistry 2005; 280(2):1499-505, 2005.Czeloth, N., G. Bernhardt, F. Hofmann, H. Genth, R. Foerster. Journal of Immunology 2005; 175(5):2960-7.Genth H, Huelsenbeck J, Hartmann B, Hofmann F, Just I, Gerhard R. FEBS Lett. 2006;580(14):3565-9Huelsenbeck J, Dreger S, Gerhard R, Barth H, Just I, Genth H. Infect Immun. 2007;

75(2):801-9.

First name:Harald

Last name:Genth

Acad. Title:Dr. rer. nat.



Further information:www.mh-hannover.de/institute/toxikologie

Department and function:Group Leader, Laboratory of Molecular Immunology; ClinicalImmunology

Education:1993 PhD in Chemistry and Molecular Biology, Technical

University (TU) Berlin1999 Habilitation in Immunology, Hannover Medical School

Positions:1994-1996: Research Associate, Dept. of Clinical Immunology,

Hannover Medical School 1994: Visiting Scientist, Dept. of Immunology, University of

Utrecht, The Netherlands1997: EMBO Research Fellow, Dept. of Pathology, CMU

Geneva, Switzerland1997-recent: Research Group Leader, and from 2002 on, Scientific

Director and Head of the Laboratory of Molecular Immunology at the Department of Clinical Immunology, Hannover Medical School

Major research interests:I) Analysis of molecular mechanisms underlying immunoregulationduring disease development in gene knockout mice.II) Signal transduction of G-protein coupled receptors.III) Gene regulation of IgG Fc receptors and their targeting for theestablishment of new therapeutic strategies.

Selected Publications:Schiller C. et al. Eur J Immunol. 2000; 30:481-490.Baumann U. et al. J Immunol. 2000; 164:1065-1070.Baumann U. et al. J Immunol. 2001; 167:1022-1027.Chouchakova N. et al. J Immunol. 2001; 166:5193-5200.Heusohn F. et al. J Immunol. 2002; 168:2857-2864.Radeke HH. et al. J Biol Chem. 2002; 277:27535-27544.Shushakova N. et al. J Clin Invest. 2002; 110:1823-1830.Nieswandt B. et al. Int Immunol. 2003; 15:341-349.Godau J, et al. J Immunol. 2004; 173(5):3437-45Skokowa J, et al. J Immunol. 2005; 174(5):3041-50.Wingender G, et al. Immunology. 2006; 117(1):117-26.Kumar V, et al. J Clin Invest. 2006;116(2):512-20.Konrad S, et al. Br J Haematol. 2006 Aug;134(3):345-7

First name:J. Engelbert

Last name:Geßner

Acad. Title:Prof. Dr. rer.nat.Dr. hum.biol.habil.



Further information:www.mh-hannover.de/kliniken/immun

Department and function:Director, Molecular Biology

Education:1982 B.S. Eberhard-Karls-University, Tübingen,) 1983 M.S. Friedrich-Miescher-Laboratory (FML) of

the Max-Planck-Society, Tübingen1986 Ph.D. Max-Planck-Society, Tübingen1987 - 1989 Postdoc at the Mount Sinai Hospital Res.

Institute, Toronto, Canada

Positions:June 1989- July 1994 Head of an independent research group at

Max-Delbrück-Lab., Cologne, GermanyApril 1994 Habilitation: University of Cologne Aug. 1994 - July 1997 Associate Staff Scientist, The Jackson

Laboratory, Bar Harbor, MEAug. 1997 - June 1999 Staff Scientist , The Jackson Laboratorysince July 1999 Professor for Molecular Biology, MHH

Major research interests:The main research interest of the group lies on the analysis of the molecular mechanisms underlying developmental processes during mammalian embryogenesis. Development of the Notochord The notochord is a transient embryonic structure that serves as a signaling center that is essential for the dorsoventralpatterning of the spinal cord and somites. Various mutations in mice disturb the development or maintenance of the notochord. Identification and functional characterization of the genes affected by these mutations is the subject of several projects. Somitogenesis Somites form as the result of segmentation of the paraxial mesoderm. They give rise to the vertebrae, ribs, the epaxial and hypaxialmuscles and the dorsal dermis. Their formation lays the basis for the metameric arrangement of the vertebrae and of the spinal ganglia. The formation of segments as well as their subdivision into cranial and caudal compartments is the subject of our investigations. We analyse the role of Notch signalling in these processes as well as spontaneous mouse mutants in which somitogenesis is disrupted.

Selected Publications:Cordes R, Schuster-Gossler K, Serth K, Gossler A. Development. 2004; 131:1221-33Bussen M, Petry M, Schuster-Gossler K, Leitges M, Gossler A, Kispert A. Genes Dev. 2004; 18(10):1209-21.Abdelkhalek HB, Beckers A, Schuster-Gossler K, Pavlova MN, et al. Genes Dev. 2004; 18(14):1725-36Hofmann M, Schuster-Gossler K, Watabe-Rudolph M, Aulehla A, Herrmann BG, Gossler A. Genes Dev. 2004; 18(22):2712-7Schroder N, Sekhar A, Geffers I, Muller J, Dittrich-Breiholz O, Kracht M, Wedemeyer J, Gossler A. Gastroenterology. 2006;130(3):902-7.Schuster-Gossler K, Cordes R, Gossler A. Proc Natl Acad Sci U S A. 2007; 104(2):537-42.

First name:Achim

Last name:Gossler




Further information:http://www.mh-hannover.de/institute/molekularbiologie/

Department and function:Chair of Molecular Pneumology, Department of Respiratory Medicine

Education:2000 MD, Justus-Liebig-University, Giessen2004 Habilitation in Medicine, Free University Berlin

Positions:2000: Visiting Research Fellow (DAAD), National Heart and

Lung Institute, Imperial College, London, UK2000-2002: Clinical Research Fellow, Charité, Berlin2002-2003: Jun.-Professor of Respiratory Immunology and

Infectiology, Research Center Borstel and University of Lübeck

2003-2004: Senior Lecturer and head, Molecular Pneumology, Allergy Centre, Charité, Berlin

2004-2006: Assoc. Prof. (PD), later acting director, Institute of Occupational Medicine, Charité, Berlin

Since 2006: Prof. and Chair, Molecular Pneumology, Hannover Medical School

Major research interests:Neuroimmune mediators of inflammationPathophysiology of obstructive airway diseasesPathophysiology of occupational and environmental diseases

Selected Publications:Heppt W, Dinh QT, Cryer A, Zweng M, Noga O, Peiser C, Melvan M, Witt C, Fischer A, Groneberg DA. Clin Exp Allergy. 2004 Jul;34(7):1105-10.Groneberg DA, Niimi A, Dinh QT, Cosio B, Hew M, Fischer A, Chung KF. Am J Respir Crit Care Med. 2004 Dec 15;170(12):1276-80.Groneberg DA, Peiser C, Eynott PR, Welker P, Erbes R, Witt C, Chung KF, Fischer A. Biol Chem. 2005 Jan;386(1):53-9.Feleszko W, Zawadzka-Krajewska A, Matysiak K, Lewandowska D, Peradzynska J, Dinh QT, Hamelmann E, Groneberg DA, Kulus M. J Allergy Clin Immunol. 2006 Jan;117(1):97-102.Reviews:Groneberg DA, Fischer A, Chung KF, Daniel H. Am J Respir Cell Mol Biol. 2004 Mar;30(3):251-60.Groneberg DA, Poutanen SM, Low DE, Lode H, Welte T, Zabel P. Lancet Infect Dis. 2005 Mar;5(3):147-55.Groneberg DA, Rabe KF, Fischer A. Eur J Pharmacol. 2006 Mar 8;533(1-3):182-94. Groneberg DA, Harrison S, Dinh QT, Geppetti P, Fischer A. Curr Drug Targets. 2006 Aug;7(8):1005-10.

First name:David

Last name:Groneberg




Further information:www.mh-hannover.de/5534.html

Department and function:Head of Junior Research Group Immunodynamics, HZI

Education:1999 Diploma in Biochemistry, University of

Witten/Herdecke, Witten1999 PhD in Biology (Immunology), University of

Witten/Herdecke, Witten

Positions:2003-recent Junior Research Group Leader at the HZI, Braunschweig

Major research interests:Analysis of cell migration in vitro and in vivoT cell activationImmunological defence against pathogens

Selected Publications:Gunzer, M., Kämpgen, E., Bröcker, E.-B., Zänker, K.S., Friedl, P. Adv. Exp. Med. Biol. 1997; 417: 97-103.Gunzer, M., Friedl, P., Niggemann, B., Bröcker, E.-B., Kämpgen, E., Zänker, K.S. J.Leukoc.Biol. 2000; 67: 622-629.Gunzer, M., Schäfer, A., Borgmann, S., Grabbe, S., Zänker, K.S., Bröcker, E.-B., Kämpgen, E., Friedl, P. Immunity 2000; 13: 323-332Gunzer, M., Weishaupt, C., Planelles, L., Grabbe, S. J Immunol Methods 2001; 258: 55-63Gunzer, M., Weishaupt C., Hillmer A., Basoglu Y., Friedl P., Dittmar K.E., KolanusW., Varga G., Grabbe S. Blood 2004; 104:2801-2809.Gunzer M, Riemann H, Basoglu Y, Hillmer A, Weishaupt C, Balkow S, et al. Blood. 2005; 106(7):2424-32.Friedl P, den Boer AT, Gunzer M. Nat Rev Immunol. 2005 Jul;5(7):532-45.Behnsen J, Narang P, Hasenberg M, Gunzer F, Bilitewski U, Klippel N, Rohde M, Brock M, Brakhage AA, Gunzer M. PLoS Pathog. 2007 Feb 2;3(2):e13 [Epub aheadof print]

First name:Matthias

Last name:Gunzer

Acad. Title:Dr.

Address:HZIMascheroder Weg 1D-38124 Braunschweig


Further information:http://www.helmholtz-hzi.de

Department and function:Head Vaccine Research Group, Microbial Pathogenesis and Vaccine Research, Division of Microbiology, HZI Braunschweig

Education:1976-1981 Medicine, National University Rosario, Argentina1982-1986 Specialisation in Bacteriology, Rosario, Argentina 1988 MD, University of Genoa, Italy1989 Qualifying Medical Graduates Examination, School of

Medicine and Surgery, Genoa, Italy1993 PhD in Microbiology, University of Genoa, Italy2000 Habilitation Medical Microbiology, Hanover Medical

School

Positions:Since 1994 Head Vaccine Research, GBF, Braunschweig, Germany1991 - 1993 Laboratory of Microbial Pathogenesis, Univ. Genoa, Italy1989 - 1991 Division of Microbiology, GBF, Braunschweig, Germany1986 - 1989 Institute of Microbiology, Genoa, Italy1982 - 1986 National University of Rosario, Argentina1982 - 1986 Italian Hospital, Rosario, Argentina1982 - 1986 Children Hospital, Rosario, Argentina

Major research interests:Vaccinology, mucosal immunity, development of antigen delivery systems and adjuvants.

Selected Publications:Schulze K, Goldmann O, Toppel A, Medina E, Guzman CA. Vaccine. 2005; 23(11):1408-13.Rharbaoui F, Bruder D, Vidakovic M, Ebensen T, Buer J, Guzman CA. J Immunol. 2005; 174(3):1317-24Guzman CA, Cebolla A, Beltrametti F, Staender LH, de Lorenzo V. FEBS Lett. 2005; 579(3):813-8.Borsutzky S, Kretschmer K, Becker PD, Muhlradt PF, Kirschning CJ, Weiss S, Guzman CA. J Immunol. 2005; 174(10):6308-13.Schulze K, Medina E, Guzman CA. Vaccine. 2006; 24(9):1446-50.Borsutzky S, Ebensen T, Link C, Becker PD, Fiorelli V, Cafaro A, Ensoli B, Guzman

CA. Vaccine. 2006; 24(12):2049-56.Becker PD, Fiorentini S, Link C, Tosti G, Ebensen T, Caruso A, Guzman CA. Vaccine. 2006;24(25):5269-76.Link C, Ebensen T, Standner L, Dejosez M, Reinhard E, Rharbaoui F, Guzman CA.Microbes Infect. 2006;8(8):2262-9.Schulze K, Olive C, Ebensen T, Guzman CA. Vaccine. 2006;24(35-36):6088-95Ebensen T, Schulze K, Riese P, Link C, Morr M, Guzman CA. Vaccine. 2007; 25(8):1464-1469Olive C, Schulze K, Sun HK, Ebensen T, Horvath A, Toth I, Guzman CA. Vaccine. 2007;25(10):1789-97.

First name:Carlos Alberto

Last name:Guzman

Acad. Title:MD, PhD

Address:HZIMascheroder Weg 138124-Braunschweig


Department and function: Director, Nephrology; Chairman, Department of Internal Medicine

Education:1972-1982 Chemistry, Art History, Medicine in

Tübingen, Berlin and Cardiff

Positions:1992-1996 Assistenzarzt FU Berlin1996-1999 Postdoctoral Fellowship Yale University1992-1997 Professor of Medicine, Franz-Volhard-Klinik

at the Max Delbrück Centre, Berlin1999 Professor of Medicine, MHH

Major research interests:I am interested in acute and chronic changes of the vasculature. I havestarted in analysing signal transduction pathways in vascular smooth muscle cells and gradually moved into endothelial cells. Additionally, I am interested in vascular development, circulating endothelialprogenitor cells and stem cells in the kidney.

Selected PublicationsSchwarz A, Mengel M, Gwinner W, Radermacher J, et al. Kidney Int. 2005; 67(1):341-8Fliser D, Wagner KK, Loos A, Tsikas D, Haller H. J Am Soc Nephrol. 2005; 16(4):1135-40.Schwarz A, Gwinner W, Hiss M, Radermacher J, Mengel M, Haller H. Am J Transplant. 2005; 5(8):1992-6Gwinner W, Menne J, Lonnemann G, Bahlmann F, Koch KM, Haller H. Int J ArtifOrgans. 2005 Dec;28(12):1224-7.Agrawal R, Marx A, Haller H. J Hypertens. 2006; 24(1):185-92Haller H, Viberti GC, Mimran A, Remuzzi G, Rabelink AJ, Ritz E, Rump LC, Ruilope LM, Katayama S, Ito S, Izzo JL Jr, Januszewicz A. J Hypertens. 2006; 24(2):403-8.Menne J, Meier M, Park JK, Boehne M, Kirsch T, Lindschau C, Ociepka R, LeitgesM, Rinta-Valkama J, Holthofer H, Haller H. Kidney Int. 2006 Oct;70(8):1456-62. Schwarz A, Rustien G, Merkel S, Radermacher J, Haller H. Nephrol Dial Transplant. 2007 Feb;22(2):584-91Tossidou I, Kardinal C, Peters I, Kriz W, Shaw A, Dikic I, Tkachuk S, Dumler I, Haller H, Schiffer M. J Biol Chem. 2007 Jan 9; [Epub ahead of print]Meier M, Park JK, Overheu D, Kirsch T, Lindschau C, Gueler F, Leitges M, Menne J, Haller H. Diabetes. 2007 Feb;56(2):346-54.

First name:Hermann

Last name:Haller




Further information:[email protected]

Department and function:Head, Gene Regulation and Differentiation And Division of Molecular Biotechnology, HZI Braunschweig

Education:1969-1974 University of Stuttgart-Hohenheim, Food technology1974-1977 PhD thesis at University of Konstanz, Biology

Positions:1978-1980 Post-Doc at MPI f. Molecular Genetics, Berlin and

DKFZ, Heidelberg1981- Research fellow, group leader, head of dept.,

head of division, HZI, Braunschweig

Major research interests:1. Signal transduction in the cytokine system (signalling molecules

and their impact on transcription, cellular and systemic consequences)

2. Biotechnology with mammalian cells (protein production, viral vectors, cellular vaccines)

Selected Publications:Kröger A, Dallügge A, Kirchhoff S., Hauser H. Oncogene 2003, 22:1045-1056Spitzer D, Dittmar KE, Rohde M, Hauser H, Wirth D. J Virol. 2003; 77(10):6070-5Koster M, Lykke-Andersen S, Elnakady YA, Gerth K, et al. Exp Cell Res. 2003;

286(2):321-31Unsinger J, Lindenmaier W, May T, Hauser H, Wirth D. Biochem Biophys Res

Commun. 2004; 319(3):879-87Niedick I, Froese N, Oumard A, Mueller PP, Nourbakhsh M, Hauser H, Koster M. J

Cell Sci. 2004; 117(Pt 16):3447-58Wirth D, Hauser H. Methods Mol Biol. 2004;267:467-76.May T, Hauser H, Wirth D. Nucleic Acids Res. 2004; 32(18):5529-38May T, Wirth D, Hauser H, Mueller PP. Biochem Biophys Res Commun. 2005;

327(3):734-41May T, Mueller PP, Weich H, Froese N, Deutsch U, Wirth D, Kroger A, Hauser H.J Biotechnol. 2005; 120(1):99-110.Froese N, Schwarzer M, Niedick I, Frischmann U, Koster M, Kroger A, Mueller PP,

Nourbakhsh M, Pasche B, Reimann J, Staeheli P, Hauser H. Mol Cell Biol. 2006; 26(1):293-302.

Frahm T, Hauser H, Koster M. J Cell Sci. 2006 Mar 15;119(Pt 6):1092-104.Schucht R, Coroadinha AS, Zanta-Boussif MA, Verhoeyen E, Carrondo MJ, Hauser

H, Wirth D. Mol Ther. 2006 Aug;14(2):285-92.

First name:Hansjörg

Last name:Hauser

Acad. Title:Dr. rer. nat

Address:HZIMascheroder Weg 138124 Braunschweig

Phone and e-mail:++49 [email protected]


Department and function:Clinical ImmunologyResearch Associate

Education:1990 MD, Hannover Medical School

Positions:1990-1992: Internship, Dept. of Immunology and Transfusion

Medicine, Hannover Medical School 1992-1995: Research Fellowship (German Research Council, DFG)

in the Laboratory of Immunobiology, Dana-Farber Cancer Institute/Harvard Medical School, Boston, USA

1995-recent: Resident in Internal Medicine, Clinical Immunology, Hannover Medical School

Major research interests:Analysis of NK cell functions in HIV infectionPrognostic factors in HIV infectionChemokines and chemokine coreceptorsImpact of GBV-C coinfection on HIV progression

Selected Publications:Tillmann HL, Heiken H, Knapik-Botor A, et al. N Engl J Med. 2001; 345(10):715-24.Grosse V, Schulte A, Weber K, Mendila M, Jacobs R, Schmidt RE, Heiken H. AIDS 2002; 16(7):1075-7.Tillmann HL, Stoll M, Manns MP, Schmidt RE, Heiken H. AIDS. 2002; 16(5):808-9.Jacobs R, Weber K, Wendt K, Heiken H, Schmidt RE. J Clin Immunol. 2004; 24(3):281-6. Jacobs R, Heiken H, Schmidt RE. Mol Immunol. 2005; 42(2):239-49.Ansari AW, Bhatnagar N, Dittrich-Breiholz O, Kracht M, Schmidt RE, Heiken H. IntImmunol. 2006;18(10):1443-51

First name:Hans

Last name:Heiken

Acad. Title:Dr. med.




Department and function:Group Leader, Molecular Cardiology (Cardiology and Angiology)

Education:1994 PhD in Biology (Genetics and Developmental Biology),

University of ZürichZürich, CH

Positions:1994-1996: Post Doc in the Department of Biology at the EMORY University in Atlanta (Georgia, USA)1997-2001: Post Doc in the Department of Cardiology and

Angiology of Hannover Medical School2001-recent: Group Leader in Molekular Cardiology in the

Department of Cardiology and Angiology

Major research interests:Analysis of mechanisms of stress-dependent signal transductionresponsible for the transition of compenatory hypertrophy to decompensated hypertrophy in the heart. Focus on the gp130-JAK/STAT signaling pathway and AP-1 transcription factors.Regulation and role of pro-angiogenic gene CCN1 in the pathophysiology of the heart.

Selected Publications:Hilfiker-Kleiner D, Hilfiker A, Schieffer B, Engel D, Mann DL, Wollert KC, DrexlerH Cardiovasc Res. 2002; 53(2):460-469.

Hilfiker A., Hilfiker-Kleiner D., Fuchs M., Kaminski K., Lichtenberg, A., RothkötterH., Schieffer B., and Drexler H. Circulation. 2002; 106(2):254-260

Podewski E.K., Hilfiker-Kleiner D., Hilfiker A., Morawitz H., Lichtenberg A., Wollert K.C. and Drexler H. Circulation. 2003Hilfiker-Kleiner D, Kaminski K, Kaminska A., Fuchs M., Klein G., Podewski E., Kiian I., Wollert K.C., Hilfiker A., Drexler H. Circulation 2004; 109(18):2227-33Hilfiker-Kleiner D, Hilfiker A, Fuchs M, et al. Circ Res. 2004; 95(2):187-95.Schieffer B, Selle T, Hilfiker A, Hilfiker-Kleiner D, et al. Circulation. 2004; 110(22): 3493-500.Hilfiker-Kleiner D, Hilfiker A, Kaminski K, Schaefer A, Park JK, Michel K, Quint A, Yaniv M, Weitzman JB, Drexler H. Circulation. 2005; 112(10):1470-7.Hilfiker-Kleiner D, Hilfiker A, Castellazzi M, Wollert KC, Trautwein C, SchunkertH, Drexler H. Cardiovasc Res. 2006;71(1):108-17.Hilfiker-Kleiner D, Landmesser U, Drexler H. J Am Coll Cardiol. 2006;48(9 Suppl):A56-66Hilfiker-Kleiner D, Kaminski K, Podewski E, Bonda T, Schaefer A, Sliwa K, Forster O, Quint A, Landmesser U, et al. Cell. 2007;128(3):589-600.

First name:Denise

Last name:Hilfiker-Kleiner

Acad. Title:PhD



Further information:www.mh-hannover.de/cardiology

Department and function:Professor, Biochemistry (Physiological Chemistry)

Education:1980 Diploma in Biology, University of Hannover1985 Ph. D., Ludwig-Maximilians-University Munich1993 Habilitation in Immunology, Medical School Hannover

Positions:1985-1987: Postdoctoral fellow at the Weizmann Institute of

Science, Rehovot, Israel1987-2001: Group leader, Institute of Pharmacology, Medical

School Hannover2001-2003: GBF-BraunschweigSince 2003: Professor for Biochemistry of Cellular Signal

Transduction, Institute of Biochemistry/Physiological Chemistry, Medical School Hannover

Major research interests:Post-transcriptional control of gene expression in inflammation

- cis-acting RNA elements- regulatory RNA-binding proteins- signalling pathways affecting post-transcriptional mechanisms

Selected Publications:Winzen R., Kracht M., Ritter B., Wilhelm A., Chen C.-Y.A., Shyu A.-B., Müller M., Gaestel M., Resch K., Holtmann. H. EMBO J. 1999; 18:4969-4980.Holtmann H., Winzen R., Holland P., Eickemeier S., Hoffmann E., Wallach D., Malinin N., Cooper J.A., Resch K., Kracht M. Mol. Cell. Biol. 1999; 19:6742-6753.Bollig F., Winzen R., Kracht M., Ghebremedhin B., Ritter B., Wilhelm A., Resch K., Holtmann H. Eur. J. Biochem. 2002; 269:5830-5839.Bollig F, Winzen R, Gaestel M, Kostka S, Resch K, Holtmann H. Biochem BiophysRes Commun. 2003;301(3):665-7Winzen R, Gowrishankar G, Bollig F, Redich N, Resch K, Holtmann H .Mol Cell Biol. 2004; 24(11):4835-47Gowrishankar G, Winzen R, Bollig F, Ghebremedhin B, Redich N, Ritter B, Resch K, Kracht M, Holtmann H. Biol Chem. 2005; 386(12):1287-93. Gowrishankar G, Winzen R, Dittrich-Breiholz O, Redich N, Kracht M, Holtmann H.Biol Chem. 2006;387(3):323-7.

First name:Helmut

Last name:Holtmann




Further information:www.mh-hannover.de/institute/biochemie

Department and function:Institute for Transfusion Medicine, Group Leader Cell Therapy

Education:1990-97 Graduated in Medicine, University of Bochum1999 M.D., University of Bochum1998-99 Postgraduate training in Hematology and Oncology,

University of Cologne2002-05 Postgraduate training in Transfusion Medicine,

University of Düsseldorf and Hannover Medical School

Positions:1998-99 Resident, Internal Medicine, University of Cologne2000-02 Research Fellow, FHCRC, Seattle, USA2002-04 Physician, Cord Blood Bank, Institute for Transplantation

Diagnostics & Cell Therapies, University of Düsseldorf2004-recent Group leader, Institute for Transfusion Medicine,

Hannover Medical School, Hannover

Major research interests:Cell and Gene Therapy, Immunogenetics, Stem Cell Biology, Large Animal Studies, Stem Cell Transplantation

Selected Publications:Horn, P.A., J. Morris, A. Bukovsky, et al. Gene Therapy 2002. 9: 1464-1471Neff, T., P.A. Horn, V.E. Valli, A.M. Gown, et al. Blood 2002. 100: 2026-2031Horn, P.A.*, M.S. Topp*, J.C. Morris, R.S. Riddell, et al. Blood 2002. 100: 3960-7Neff, T.*, P.A. Horn*, et al. Journal of Clinical Investigation 2003. 112: 1581-1588Horn, P.A., B.M. Thomasson, B.L. Wood, et al. Blood 2003. 102: 4329-4335Storek, J., T. Gillespy III, H. Lu, A. Joseph, et al. Blood 2003. 101: 4209-4218Kiem, H.P., et al. Molecular Therapy 2004 9, 389-395Horn, P.A., K.A. Keyser, L.J. Peterson, T. Neff, et al. Blood 2004. 103: 3710-3716Horn, P.A., Morris, J.C., Neff, T., Kiem, H.P. Molecular Therapy 2004. 10, 417-431Horn, P.A., Blasczyk, R. Tissue Antigens 2005. 66, 56-57Horn, P.A., Mansmann V., Blasczyk, R. Tissue Antigens 2005. 66, 335-337Horn, P.A., DeLuca, D., Jindra, P., Blasczyk, R. 2006. Human Immunology 2005; 66(12):1254-7.Eiz-Vesper, B., Horn, P. A., et al. Transfusion 2006;46(7):1210-20.Horn PA, Elsner HA, Blasczyk R. Pediatr Transplant. 2006 Sep;10(6):753-4.Horn PA, Tani K, Martin U, Niemann H. Cloning Stem Cells. 2006 Fall;8(3):124-9.

First name:Peter A.

Last name:Horn

Acad. Title:Dr. med.



Further information:www.mh-hannover.de/institute/transfusion/transfusionsmedizin/

Department and function: Group Leader, Clinical Immunology

Education:1981-1986 Biology in Hannover

Positions:1987-recent Scientist in the Division of Clinical Immunology, MHH1992 PhD in Biology, MHH2003 Habilitation in Immunology, MHH

Major research interests:Analysis of Natural Killer (NK) cell subpopulations. Our particularinterest is focused on NK cells with weak cytoxic capacity that aresupposed to play an important role in immune regulation.

Selected PublicationsJacobs R, Hintzen G., Kemper A., Beul K., et al. Eur J Immunol 2001; 31: 3121-3126.Jacobs R., Pawlak C. R., Mikeska E., Meyer-Olson D., et al.. Rheumatol 2001; 40: 868-875.Kittner J. M., Jacobs R., Pawlak C. R., Heijnen C. J., Schedlowski M., Schmidt R. E.. Rheumatol 2002; 41: 1031-1039.Straub R. H., Kittner J. M., Heijnen C. J., Schedlowski M., Schmidt R. E., Jacobs R. J Rheumatol 2002; 29: 1659-1664.Jacobs R, Weber K, Wendt K, Heiken H, Schmidt RE J Clin Immunol. 2004; 24(3):281-6Jacobs R, Heiken H, Schmidt RE Mol Immunol. 2005; 42(2):239-49Wendt K, Wilk E, Buyny S, Buer J, Schmidt RE, Jacobs R. J Leukoc Biol. 2006; 80(6):1529-41.

First name:Roland

Last name:Jacobs

Acad. Title:PD Dr.




Department and function:Assistant and research group leader department gastroenterology, hepatology, endocrinology

Education:1996 Master in medicine, University of Hamburg1997 MD, Dept. Pharmacology, Friedrich-Alexander

University, Erlangen

Positions:1996-1999: Research fellow and assistant Dept. Gastroenterology,

MHH, Hannover1998: Research Fellow, German Primate Center Goettingen1999-2003: Postdoctoral fellowship dept. cancer immunology and

AIDS, Dana Farber Cancer Institue, Harvard MedicalSchool, Boston

2003-recent: Assistant and research group leader departmentGastroenterology, Hepatology, Endocrinology

Major research interests:Mechanisms and regulation of immune tolerance in autoimmunity, alloimmunity and chronic infection

Selected Publications:Jaeckel E, Heringlake S, Berger D, Brabant G, Hunsmann G, Manns MP. Diabetes 1999; 48(1):209-14. Jaeckel E, Cornberg M, Santantonio T, Mayer J, et al. New England Journal of Medicine 2001; 345:1452-1457.Jaeckel E, Klein L, Martin-Orozco N, von Boehmer H. J Exp Med 2003; 197: 1635-1644.Wiegand J, Jackel E, Cornberg M, Hinrichsen H, et al. Hepatology 2004; 40:98-107.Jaeckel E, El-Armouche A, Boheler KR, Boknik P, et al. Biochem Biophys Res Comm 2004; 318: 219-226.Jaeckel E, Lipes MA, von Boehmer H. Nat Immunol 2004; 5: 1038-1035.Jaeckel E, von Boehmer H, Manns MP Diabetes 2005; 54: 306-310.Jaeckel E, Kretschmer K, Apostolou I, von Boehmer H. Semin Immunol. 2006; 18(2):89-92

First name:Elmar

Last name:Jaeckel

Acad. Title:MD

Address:OE6819TPFZ, K11/01-1450


Further information:www.mh-hannover.de/kliniken/gastro/gastro.htm

Department and function:Group leader (Institute of Medical Microbiology and Hospital Epidem.)

Education:1996 PhD in Biology (Microbiology/Biochemistry/Cell

Biology), Ruhr-University Bochum, Germany

2003 Habilitation in Medical Microbiology, University of Würzburg, Germany

Positions:1998-1999: Junior Research Group Leader, Dept. Medical

Microbiology, Ruhr-University Bochum, Germany

1999-2000: Post-Doctoral Research, Institute for Cellular Pathology, Université Catholique de Louvain, Bruxelles/Brussel, Belgium

2000-2004: Junior Research Group Leader, Institute for Hygiene and Microbiology, University of Würzburg, Germany

from 2004: Research Group Leader “Cellular Microbiology”Institute for Medical Microbiology and Hospital Epidem. at Hannover Medical School

Major research interests:Characterization of virulence mechanisms of pathogenic bacteriaBacterial sensing, signal transduction and gene regulationBacterial motility and secretion processesInfluence of bacteria on cellular signaling and immune responses in health (commensals) and disease (pathogens) in the gastrointestinal tract

Selected Publications:Schreiber S., Stüben M., Groll C., Scheid P., et al. Natl. Acad. Sci. 2004; 101: 5024-5029.Niehus E., Gressmann H., Ye F., Schlapbach R., et al. Mol. Microbiol. 2004; 52: 947-961. Schmausser B., Josenhans C., Endrich S., Suerbaum S., et al. Infect. Immun. 2004; 72: 6773-6779.Schreiber S, Bucker R, Groll C, Azevedo-Vethacke M, Garten D, Scheid P, et al. Infect Immun. 2005; 73(3):1584-9Schreiber S, Bucker R, Groll C, Azevedo-Vethacke M, Scheid P, Gatermann S, Josenhans C, Suerbaum S. Arch Microbiol. 2006;184(5):335-40.Andrzejewska J, Lee SK, Olbermann P, Lotzing N, Katzowitsch E, Linz B, Achtman M, Kado CI, Suerbaum S, Josenhans C. J Bacteriol. 2006;188(16):5865-77.Ye F, Niehus E, Drlica K, Josenhans C, Suerbaum S. Int J Med Microbiol. 2007 Jan 31; [Epub ahead of print]

First name:Christine

Last name:Josenhans

Acad. Title:P.D. Dr. rer. nat. (Ph.D.)



Further information:www.mh-hannover.de/institute/mikrobiologie/

Department and function: Head of Department of Toxicology

Education:1976-1980 Pharmacy, Universität Münster1981-1987 Medicine, Freie Universität Berlin

Positions:1989-1995 Postdoc positions in Pharmacology at the Universities

of Giessen, Essen, Homburg/Saar1997 Post Orange Fellowship of INSERM in Nice, France1995-2000 Assistant Professor at the University of Freiburg2000 Professor of Toxicology, MHH

Major research interests:The molecular and cellular mode of action of bacterial proteintoxins and the functional consequences on the signal transductionof the target cells.

Selected Publications

Vetter, IR, Hofmann, F, Wohlgemut, S, Herrmann, C, and Just, I (2000) J. Mol. Biol. 301:1091-1095 Wilde, C, Chhatwal, GS, Schmalzing, G, Aktories, K, and Just, I (2001) J. Biol. Chem., 276:9536-9542Wilde, C, Barth, H, Sehr, P, Han, L, Schmidt, M, Just, I, Aktories, K (2002) J. Biol. Chem. 277:14771-14776 Gerhard, R, John, H, Aktories, K, and Just, I (2003) Mol. Pharmacol. 63:1349-1355Genth H, Gerhard R, Maeda A, Amano M, Kaibuchi K, Aktories K, Just, I. (2003) J. Biol. Chem. 278: 28523-28527Ahnert-Hilger G, Höltje M, Große G, Pickert G, Mucke C, Nixdorf-Bergweiler B, Boquet P, Hofmann F, and Just I. (2004) J. Neurochem. 90:9-18Gerhard, R, Tatge, H., Genth, H., Thum, T., Borlak, J., Fritz, G., and Just, I. (2005)J. Biol. Chem. 280:1499-1505Theodoresu, D, Wittke, S, Ross, MM, Walden, M, Conaway, M, Just, I, Mischak, H, Frierson, H (2006) Lancet Oncology 7:230-240.

First name:Ingo

Last name:Just

Acad. title:Prof. Dr.



Further information:http://www.mh-hannover.de/institute/212.html?&no_cache=1/

Department and function:Professor, Molecular Biology of Vertebrates

Education:1983-1989 University of Tübingen, Biochemistry1987-1988 Queen Mary College, London, Biochemistry1989-1990 Diploma thesis, MPI Tübingen1990-1993 PhD thesis, MPI Tübingen

Positions:1993-1994 Postdoc, MPI Tübingen1994-1996 Postdoc, Harvard University1997-2001 Group leader, MPI FreiburgSince 2001 C3 Professor, MHH

Major research interests:Genetic control of vertebrate (mouse) development:- Organogenesis (organs of mesodermal origin like kidneys, skeleton,

muscles, heart)- Function of Wnt and Tbx genes in development

Selected Publications:Kispert A, Vainio S, McMahon AP. Development 1998; 125: 4225-4234Herrmann BG, Koschorz B, Wertz K, McLoughlin KJ, Kispert A. Nature 1999; 402: 141-146Leitges M, Neidhardt L, Haenig B, Herrmann BG, Kispert A. Development 2000; 127: 2259-2267Kohlhase J, Heinrich M, Liebers M, Frohlich Archangelo L, Reardon W, Kispert A. Cytogenet Genome Res. 2002; 98(4):274-7Moeller C, Swindell EC, Kispert A, Eichele G. Development. 2003; 130(21):5103-11. Bussen M, Petry M, Schuster-Gossler K, Leitges M, Gossler A, Kispert A. Genes Dev. 2004; 18(10):1209-21Haenig B, Kispert A . Dev Genes Evol. 2004; 214(8):407-11.Singh MK, Petry M, Haenig B, Lescher B, Leitges M, Kispert A. Mech Dev. 2005; 122(2):131-44Singh MK, Christoffels VM, Dias JM, Trowe MO, Petry M, Schuster-Gossler K, Burger A, Ericson J, Kispert A. Development. 2005 Jun;132(12):2697-707.Airik R, Bussen M, Singh MK, Petry M, Kispert A. J Clin Invest. 2006;116(3):663-74.Barrionuevo F, Taketo MM, Scherer G, Kispert A. Dev Biol. 2006;295(1):128-40.Christoffels VM, Mommersteeg MT, Trowe MO, Prall OW, de Gier-de Vries C, Soufan AT, Bussen M, Schuster-Gossler K, Harvey RP, Moorman AF, Kispert A. Circ Res. 2006 Jun 23;98(12):1555-63

First name:Andreas

Last name:Kispert




Further information:http://www.ifm-mhh.de.vu/

Department and function:Professor; Pediatric Hematology/Oncology

Education:1983-1990 Medical School (University Ulm, Munich)1992 Magister Artium, Philosophy2000 Doctorat Immunology (Institut Pasteur, Paris)

Positions:1990 Residency in Pediatrics, University Munich1991-1994 Residency and Research Associate Hôpital Necker

Enfants Malades, Paris1994-1995 Residency in Pediatrics, University Freiburg1995-1998 Clinical and Research Fellow

Children‘s Hospital, Harvard Medical School Boston1998-2000 Instructor in Pediatrics and Research Associate, Howard

Hughes Medical Instit., Harvard Medical School, Boston2000- Hannover Medical School

Major research interests:Gene Therapy, Tumor Immunology, Stem Cell Biology

Selected Publications:Snapper SB, Takeshima F, Rosen FS, Antón I, Thomas S, et al. Nat Cell Biol 2001;3:897-904Robert C, Klein C, Cheng G, Kogan A, Mulligan RC, et al. Gene Therapy 2003; 10(17):1479-86Klein C, Nguyen D, Liu CH, Mizoguchi E, Bhan AK, Rosen FS, et al. Blood 2003; 101(6):2159-66Klein C, Baum C Hematol J. 2004;5(2):103-11Cloppenborg T, Stanulla M, Zimmermann M, Schrappe M, Welte K, Klein C.Leukemia. 2005; 19(1):44-8.Rathinam C, Geffers R, Yucel R, Buer J, Welte K, Moroy T, Klein C. Immunity. 2005; 22(6):717-28.Maecker B, Mougiakakos D, Zimmermann M, Behrens M, Hollander S, Schrauder A, Schrappe M, Welte K, Klein C. Leukemia. 2006;20(4):645-9.Rathinam C, Sauer M, Ghosh A, Rudolph C, Hegazy A, Schlegelberger B, Welte K, Klein C. Leukemia. 2006;20(5):870-6.Dewey RA, Avedillo Diez I, Ballmaier M, Filipovich A, Greil J, Gungor T, Happel C, Maschan A, et al. Exp Hematol. 2006;34(9):1161-9.Klein C, Grudzien M, Appaswamy G, Germeshausen M, Sandrock I, Schaffer AA, Rathinam C, Boztug K, et al. Nat Genet. 2007 Jan;39(1):86-92.Bohn G, Allroth A, Brandes G, Thiel J, Glocker E, Schaffer AA, Rathinam C, Taub N, et al. Nat Med. 2007;13(1):38-45.

First name:Christoph

Last name:Klein

Acad. Title:Prof. Dr., PhD


Phone and e-mail:+49-511-532 [email protected]

Further information:www.mh-hannover.de/Kliniken/paed_haemonko/Klinik.htm

Department and function:Assistant Medical Director, Medical Microbiology

Education:1980 - 86 Study of Medicine at the Johannes-Gutenberg University

Mainz1988 - 91 Experimental training in Molecular Biology and Cell

Biology at the Baylor College of Medicine, Department ofCell Biology, Houston, Texas, Medical Center

2000 Consultant with board certification in Med. Microbiol.

Positions:1987 - 88 Research Assistent in the Department of Medical

Microbiology, Johannes-Gutenberg University, Mainz1991 -2000 Research Assistant and, from 2001 on, Assistant Medical

Director at the Department of Medical Microbiology, MHH

Major research interests:Basic research on …1. Chlamydia: Bacteria–host-cell interaction, regulated host-cell genes, mechanisms and signalling pathways2. Complement: Anaphylatoxic peptides C3a, C5a and their G-proteincoupled receptors as part of the innate immunity, receptor regulation on various levels including gene-regulation and interaction with cytokines

Selected Publications:Settmacher B, Rheinheimer C, Hamacher H, Ames RS, et al. Eur J Immunol. 2003; 33(4):920-7Hess S, Peters J, Bartling G, Rheinheimer C, et al. Cell Microbiol. 2003; 5(11):785-95Otto M, Hawlisch H, Monk PN, Muller M, et al. J Biol Chem. 2004; 279(1):142-51Godau J, Heller T, Hawlisch H, Trappe M, et al. J Immunol. 2004; 173(5):3437-45.Fischer SF, Vier J, Kirschnek S, Klos A, et al. J Exp Med. 2004; 200(7):905-16.Peters J, Hess S, Endlich K, Thalmann J, Holzberg D, Kracht M, Schaefer M, Bartling G, Klos A. Cell Microbiol. 2005; 7(8):1099-108Schaefer M, Konrad S, Thalmann J, Rheinheimer C, Johswich K, Sohns B, Klos A. J Biol Chem. 2005; 280(51):42113-23Johswich K, Martin M, Thalmann J, Rheinheimer C, Monk PN, Klos A. J Biol Chem. 2006;281(51):39088-95.

First name:Andreas

Last name:Klos




Further information:www.mh-hannover.de/institute/mikrobiologie/

Department and function:Dept. of Experimental Hematology (head: Prof.Dr.C.Baum),Project Leader

Education:1997 PhD in Biology (Molecular Genetics),

University of Vienna1993 Diploma (Mag.rer.nat.) in Molecular Genetics

University of Vienna

Positions:2003-present: Resarch Associate at the

Institute of Experimental Hematology(head Prof.Dr.C.Baum), Hannover Medical School

1998-2003: Research Associate at the Heinrich-Pette-Institute for Experimental Viroloy and Immunology (HPI), Hamburg

1995-1998: Assistant Professor (“Vertragsassistent”) at the University of Vienna,Institute of Medical Biochemistry.

Major research interests:- In vitro generation of Hematopoietic Stem Cells (HSCs) from

Embryonic Stem (ES-) Cells suitable for transplantation- Manipulation of stem cell self-renewal and differentiation by the

homeodomain transcription factor HOXB.

Selected Publications:Pilat, S., Carotta, S., Schiedlmeier, B., et al. (2005) PNAS, 102: 12101-12106.Will, E., Speidel, D., Wang, Z. et al. (2006) Cell Cycle, 5, 14-22.Schiedlmeier, B., Klump, H., Will, E., et al. (2003) Blood, 101: 1759-1768.Will, E., Klump, H., Heffner, N., et al. (2002) Nucl Acids Res, 30: e59.Klump,H., Schiedlmeier,B., Vogt, B., et al. (2001) Gene Ther, 8, 811-817.

First name:Hannes

Last name:Klump

Acad. Title:Dr.rer.nat.



Further information:www.mh-hannover.de/kliniken/zellth/

Department and function:Group Leader, Biochemistry (Physiological Chemistry)

Education: 1978-1985 Medical School, Charkov, Ukraine1987-1991 PhD thesis

Positions:Research Assistent

Major research interests:MAPK cascades activated by stress or cytokinesSignalling events that are triggered by p38 activity,and analyse how these events contribute to specific gene expression and cellular responses.

Selected Publications:Kotlyarov A., Neininger C., Schubert R., Eckert C., Birchmeier H-D, et al. Nature Cell Biol. 1999; 1: 94-97.Kotlyarov A, Gaestel M. Biochem. Soc. Trans. 2002; 30: 959-963.Kotlyarov A, Yannoni Y, Fritz S, Laaß K, Telliez J-B, et al. Mol. Cell. Biol. 2002; 22: 4827–4835.Shi Y, Kotlyarov A, Laabeta K, Gruber AD, Butt E, et al. Mol Cell Biol. 2003; 23(21):7732-41.Wu Y, Hannigan MO, Kotlyarov A, Gaestel M, Wu D, Huang CK. Biochem BiophysRes Commun. 2004; 316(3):666-7Schumacher S, Laass K, Kant S, Shi Y, et al. EMBO J. 2004; 23(24):4770-9.Hitti E, Iakovleva T, Brook M, Deppenmeier S, Gruber AD, Radzioch D, Clark AR, Blackshear PJ, Kotlyarov A, Gaestel M. Mol Cell Biol. 2006;26(6):2399-407Vertii A, Hakim C, Kotlyarov A, Gaestel M. J Biol Chem. 2006;281(37):26966-75.Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, Gaestel M. J Biol Chem. 2006;281(46):35511-9.Ronkina N, Kotlyarov A, Dittrich-Breiholz O, Kracht M, Hitti E, Milarski K, Askew R, Marusic S, Lin LL, Gaestel M, Telliez JB. Mol Cell Biol. 2007;27(1):170-81.

First name:Alexey

Last name:Kotlyarov

Acad. Title:MD



Further information:www.mh-hannover.de/ institute/biochemie/

Department and function:Director, Institute of Pathology

Education:1976-1982 Study of Medicine, University of Kiel1985 Doctoral thesis, University of Kiel1991 Habilitation , University of Kiel

Positions:1984 - 1993: Institute of Pathology, University of Kiel; senior

registrar since 19911993 - 1998: Professor and Deputy Director Institute of Pathology

University of Würzburgsince 1998: Professor and Head of the Department of Pathology,

Medizinische Hochschule Hannover

Major research interests:Molecular pathology of breast cancer and leukemiasDifferentiation and regeneration of normal tissues

Selected Publications:Serinsoz E, Neusch M, Busche G, Wasielewski R, Kreipe H, Bock O. Br J Haematol. 2004; 126(3):313-9.Mengel M, Jonigk D, Wilkens L, Radermacher J, von Wasielewski R, Lehmann U, Haller H, Mihatsch M, Kreipe H. Am J Pathol. 2004;165(6):2079-85.Bock O, Loch G, Schade U, Büsche G, von Wasielewski R, Wiese B, Kreipe H. Br J Haematol. 2005; 130:76-82Brakensiek K, Langer F, Schlegelberger B, Kreipe H, Lehmann U. Br J Haematol. 2005l;130(2):209-17.Lehmann U, Kreipe H. Methods Mol Med. 2006;120:65-75.Brocker V, Langer F, Fellous TG, Mengel M, Brittan M, Bredt M, Milde S, Welte T, Eder M, Haverich A, Alison MR, Kreipe H, Lehmann U. Am J Respir Crit Care Med. 2006;173(11):1276-82.Bock O, Neuse J, Hussein K, Brakensiek K, Buesche G, Buhr T, Wiese B, Kreipe H. Am J Pathol. 2006;169(2):471-81.Bock O, Hussein K, Neusch M, Schlue J, Wiese B, Kreipe H. Eur J Haematol. 2006; 77(6):463-70.Schade U, Bock O, Vornhusen S, Jager A, Busche G, Lehmann U, Kreipe H. HumPathol. 2006;37(9):1153-61Bock O, Hussein K, Brakensiek K, Buhr T, Schlue J, Wiese B, Kreipe H.Leuk Res. 2006 Oct 6; [Epub ahead of print]Mengel M, Gwinner W, Schwarz A, Bajeski R, Franz I, Brocker V, Becker T, NeippM, Klempnauer J, Haller H, Kreipe H.Am J Transplant. 2007;7(2):356-65

First name:Hans H.

Last name:Kreipe




Further information:www.mh-hannover.de/institute/pathologie

Department and function:Head of Immunology, Allergology and Clinical Inhalation Research, ITEM

Education:1981-89 Medicine in Hannover, Göttingen and Hartford (USA)1998-2000 Degree in Internal Medicine, Respiratory Medicine,

Allergology and Intensive Care Medicine, Hannover Medical School (MHH)

1999 Habilitation in Internal Medicine (MHH)

Positions:1989-93 and1995-2000: Assistenzarzt Medical School Hannover (MHH)1993-95: Postdoctoral Fellowship University Bochum and

University Southampton (German Research CouncilScholarship)

since 2000: Professor of Immunology, Allergology and Clinical Inhalation Research, MHHand Head of Department Immunology, Allergology and Clinical Inhalation Research, Fraunhofer ITEM

Major research interests:Pathophysiology and therapeutic interventions of airway diseases, in particular asthma. Preclinical and clinical research.

Selected Publications:Erpenbeck VJ, Hagenberg A, Dulkys J, Elsner J, Krentel H, et al. Am J Respir CritCare Med 2004; 169; 578-586.Hohlfeld JM, Schmiedl A, VJ Erpenbeck, Venge P, Krug N. J Allergy Clin Immunol2004; 113: 496-502.Weigt H, Muhlradt PF, Larbig M, Krug N, Braun A. J Immunol. 2004; 172:6080-6.Schaumann F, Borm PJ, Herbrich A, Knoch J, et al. Am J Respir Crit Care Med. 2004; 170(8):898-903.Baelder R, Fuchs B, Bautsch W, Zwirner J, et al. J Immunol. 2005; 174(2):783-9.Krug N, Hohlfeld JM, Geldmacher H, Larbig M, Heermann R, Lavallee N, Nguyen DT, Petzold U, Hermann R. Allergy. 2005;60(3):354-9.Erpenbeck VJ, Hagenberg A, Krentel H, Discher M, Braun A, Hohlfeld JM, Krug N. Int Arch Allergy Immunol. 2006;139(4):306-316Erpenbeck VJ, Ziegert M, Cavalet-Blanco D, Martin C, Baelder R, Glaab T, Braun A, Steinhilber W, et al. Clin Exp Allergy. 2006;36(7):930-40.Larbig M, Burtin B, Martin L, Stamm H, Luettig B, Hohlfeld JM, Krug N. Br J ClinPharmacol. 2006;62(2):158-64.

First name:Norbert

Last name:Krug


Address:Fraunhofer Institute forToxicology and Experimental MedicineNikolai-Fuchs-Str. 130625 Hannover


Further information:www.item.fraunhofer.de

Department and f unction:Group Leader and Head of the Laboratory of Molecular Diagnostics; Pathology

Education:1986-1992 University of Hannover, Biochemistry1992-1996 PhD, Molecular Biology

Positions:1996-1998 Head Laboratory of Molecular Diagnostics

Institute of Pathology, Bielefeldsince 1999 Research Group Leader and Head of the

Laboratory of Molecular Diagnostics,Institute of Pathology, Hannover Medical School

Major research interests:Epigenetics of malignant neoplasiaTumor evolutionMolecular diagnosis of neoplasiaMain focus on breast cancer and hematological neoplasia in humans

Selected Publications:Kleeberger W, Versmold A, Rothamel T, Glockner S, Bredt M, et al. Am J Pathol. 2003; 162(5):1487-94Tessema M, Langer F, Dingemann J, Ganser A, Kreipe H, Lehmann U.Leukemia. 2003; 17(5):910-8. Lehmann U, Brakensiek K, Kreipe H. Ann Hematol. 2004; 83(3):137-52Lehmann U, Kreipe H. Methods Mol Biol. 2004; 287:207-18.Langer F, Stickel J, Tessema M, Kreipe H, Lehmann U. Leuk Res. 2004; 28(10):1081-3.Brakensiek K, Langer F, Kreipe H, Lehmann U. Blood. 2004; 104(5):1586-7Tessema M, Langer F, Bock O, Seltsam A, Metzig K, Hasemeier B, Kreipe H, Lehmann U. Int J Oncol. 2005; 26(2):499-507.Langer F, Dingemann J, Kreipe H, Lehmann U. Leuk Res. 2005; 29(3):325-9.Lehmann U, Berg-Ribbe I, Wingen LU, Brakensiek K, Becker T, KlempnauerJ, et al. Clin Cancer Res. 2005; 11(10):3654-60.Brakensiek K, Langer F, Kreipe H, Lehmann U. Leuk Res. 2005; 29:1357-60.Brakensiek K, Langer F, Schlegelberger B, Kreipe H, Lehmann U. Br J Haematol. 2005; 130(2):209-17.Lehmann U, Kreipe H. Methods Mol Med. 2006;120:65-75.Brocker V, Langer F, Fellous TG, Mengel M, Brittan M, Bredt M, Milde S, Welte T, Eder M, Haverich A, Alison MR, Kreipe H, Lehmann U. Am J RespirCrit Care Med. 2006;173(11):1276-82.Brakensiek K, Wingen LU, Langer F, Kreipe H, Lehmann U. Clin Chem. 2007; 53(1):17-23.

First name:Ulrich

Last name:Lehmann

Acad. Title:PD Dr. rer. nat.



Further information:www.mh-hannover.de/ institute/pathologie/

Department and function:Division of Microbiology, Head of the Junior Research Group Infection Genetics, HZI – Helmholtz Center for Infection Research

Education:1997 PhD in Biology (Genetics), University of Bielefeld

Positions:1997-2000: Postdoctoral Research Fellow at the University of

Pennsylvania, Medical School, Philadelphia, USA2000-2001: Senior Research Scientist at the Institute of Mammalian

Genetics, National Research Centre for Health and Environment (GSF), in Munich

2001-recent: Junior Research Group Leader at the HZI.

Major research interests:Host-pathogen interactions, Mouse infection models, Macrophage functions during infections, Clearance of apoptotic cells, Infection Genetics.

Selected Publications:Hough, R.B., Lengeling, A., Bedian, V., Bucan, M. PNAS 1998; 95: 13800-13805.Lengeling, A., Wiltshire, T., Otmani, C., Bucan, M. Genome Res.1999; 9: 732-738.Lengeling, A., Pfeffer, K. and Balling, R. Mamm. Genome 2001; 12: 261-271.Schneider, J.E., Böse, J., Bamforth, S.D., Gruber, A.D., Broadbent, C., Clarke, K., Neubauer, S., Lengeling, Bhattacharya, S. BMC Dev. Biol. 2004; 4: 16.Böse, J., Gruber, A.D., Helming, L., Schiebe, S., Wegener, I., Hafner, M., Beales, M., Köntgen, F., Lengeling, A. Journal of Biology 2004; 3, 15.Helming L, Bose J, Ehrchen J, Schiebe S, Frahm T, Geffers R, Probst-Kepper M, Balling R, Lengeling A. Blood. 2005; 106(13):4351-8Medina E, Lengeling A. Brief Funct Genomic Proteomic. 2005; 4(3):248-57.

First name:Andreas

Last name:Lengeling


Address:Mascheroder Weg 138124 Braunschweig



Department and function:Project leaderDept. Experimental Hematology

Education:1993 Master of Medicine (equivalent to MD)

Tongji Medical School, Wuhan, PR. China1998 MD, University of Hamburg, Hamburg2006 Habilitation and venia legendi in

Experimental Hematology, Hannover Medical School

Positions:1993-1995 Clinical and Research fellow, Tongji Medical School1995-1996 Clinical fellow, Clinic of Dr. Kleeberg (HOPA,

Hamburg)1996-1998 Research fellow, Center for Bone Marrow

Transplantation, University Hospital Eppendorf,Hamburg

1999-2002 Faculty member and Deputy Director Department of HematologySun Yat-Sen Memorial HospitalSun Yat-Sen University, Guangzhou, PR. China

2000-2002 Postdoctoral fellowDepartment of Cell & Virus GeneticsHeinrich-Pette-Institute, University of Hamburg

2001-04.2006 Staff scientist, project leaderDept. Hematology, Hemostaseology and Oncology Hannover Medical School

04.2006- Project leader, Dept. Experimental Hematology

Major research interests:1) Leukemogenesis of receptor tyrosine kinases;2) Stem cell biology; 3) Gene therapy

Selected Publications:Li Z et al., Science 2002;296:497Li Z et al., Leukemia 2002;16:1655-63Li Z et al., Experimental Hematology 2003; 31:1206-1214Baum C et al., Blood 2003;101:2099-2113Baum C et al., Molecular Therapy 2004;9:5-13Kustikova OS et al., Science 2005;308:1171-1174Schambach A et al., Gene Therapy 2006;13:1037-1047Kustikova OS et al., Blood 2007 in press

First name:Zhixiong

Last name:Li

Acad. Title:PD Dr.med.



Department and functionGroup Leader, Cell Biology

Education:1982-1987 Biology, Technical University of Munich1988-1992 PhD Thesis, MPI for Biochemistry, Martinsried

Positions:1992-1997 Postdoc at Washington University, St. Louis, MO, USA1997-2000 Assistant in the Department of Immunobiology,

University of Bonnsince 2000 Assistant in the Department of Cell Biology

Major research interests:Antigen processing and presentation; intracellular sorting of MHC II molecules, antigens and cofactors for antigen processing; lipid rafts and their function in MHC II biology; roles of intestinal epithelial cells in mucosal immunity

Selected Publications:Lindner R., Unanue E. EMBO J. 1996; 15: 6910-6920.Lindner R. Electrophoresis 2001; 22: 386-393.Lindner R. Traffic 2002; 3: 133-146.Karacsonyi C, Knorr R, Fulbier A, Lindner R J Biol Chem. 2004; 279(33):34818-2Karacsonyi C, Bedke T, Hinrichsen N, Schwinzer R, Lindner R. J Leukoc Biol. 2005; 78(5):1097-105.

First name:

Robert

Last name:Lindner



Phone and e-mail:++49- 511- 532-2918

[email protected]

Further information:www.mh-hannover.de/Institute/Zellbiologie/

Department and function:Group Leader, Gastroenterology, Hepatology and Endocrinologyand Molecular Biology

Education:6/96 MD1/98-12/00 Post Doc Fred Hutchinson Cancer Center, Seattle WA;

USA

Positions:since 1/96 Dept. of Gastroenterology, MHHsince 2/01 Dept.of Gastroenterology and Institute for Molecular

Biology

Major research interests:My scientific interest concentrates on the understanding of themammalian cell cycle, specifically on the control of cyclin dependentkinases. Our research tries to elucidate the molecular regulation of cyclin kinase inhibitors by proteolytic mechanisnms. We are usingbiochemistry and mouse models as our main tools.

Selected Publication:Malek NP, Sundberg H, McGrew S, Nakayama K, Kyriakides TR, Roberts J. Nature2001; 413: 323-27.Zender L, Hutker S, Liedtke C, Tillmann HL, Zender S, et al. Proc Natl Acad SciUSA 2003; 100(13):7797-802.Kossatz U, Dietrich N, Zender L, Buer J, Manns MP, Malek NP. Genes Dev. 2004; 18(21):2602-7Timmerbeul I, Garrett-Engele CM, Kossatz U, Chen X, Firpo E, Grunwald V, Kamino K, Wilkens L, Lehmann U, Buer J, Geffers R, Kubicka S, Manns MP, Porter PL, Roberts JM, Malek NP. Proc Natl Acad Sci U S A. 2006;103(38):14009-14.Kossatz U, Vervoorts J, Nickeleit I, Sundberg HA, Arthur JS, Manns MP, Malek NP.EMBO J. 2006 Nov 1;25(21):5159-70.

First name:Nisar Peter

Last name:Malek

Acad. Title:Dr.med.



Further information:http://www.mh-hannover.de/ kliniken/gastro/gastro.htm

Department and function:Director, Biophysical Chemistry

Education:1986 PhD in Biochemistry, Heidelberg University1999 Venia Legendi for Biochemistry and Biophysics,

Heidelberg University

Positions:1986 Research Associate, University of Michigan, USA1987-1990 Postdoctoral Fellow, Stanford University, USA1990-1996: Group Leader, National Institute for Medical

Research, London, UK1996-2002: Senior Group Leader, Max-Planck-Institute for

Medical Research, Heidelberg2002-: Professor of Biophysical Chemistry, MHH

Major research interests:Molecular motorsRegulation of dynamic changes in the cytoskeleton associated with cellmovements and cytokinesisG-protein mediated processes

Selected Publications:Knetsch, M.L.W., Schäfers, N., Horstmann, H., Manstein, D. J. EMBO J 2001, 20: 1620-1629.Klockow, B., Tichelaar, W., Madden, D., Niemann, H.H., Akiba, T., Hirose, K., Manstein, D.J. EMBO J 2002, 21: 240-250.Krylyshkina, O., Manstein, D.J. et al. J. Cell Biol. 2003, 161: 853-859.Reubold, T.F., Eschenburg, S., Becker, A., Kull, F.J., Manstein, D.J. Nature Struct. Biol 2003, 10: 826-830.Tsiavaliaris G, Fujita-Becker S, Manstein DJ. Nature. 2004; 427(6974):558-61.Fujita-Becker S, Durrwang U, Erent M, Clark RJ, Geeves MA, Manstein DJ. J BiolChem. 2005; 280(7):6064-71Reubold TF, Eschenburg S, Becker A, Leonard M, Schmid SL, Vallee RB, Kull FJ, Manstein DJ. Proc Natl Acad Sci U S A. 2005; 102(37):13093-8.Durrwang U, Fujita-Becker S, Erent M, Kull FJ, Tsiavaliaris G, Geeves MA, Manstein DJ. J Cell Sci. 2006; 119(Pt 3):550-8.Fujita-Becker S, Tsiavaliaris G, Ohkura R, Shimada T, Manstein DJ, Sutoh K. J BiolChem. 2006;281(47):36102-9.Fedorov R, Witte G, Urbanke C, Manstein DJ, Curth U. Nucleic Acids Res. 2006;34(22):6708-17.

First name:Dietmar

Last name:Manstein




Further information:http://www.bpc.mh-hannover.de/

Department and function:Department of Pulmonary MedicineHead, Laboratory for Experimental Lung Research

Education:1996 PhD in Biology, Justus-Liebig-University Giessen

2005 Habilitation in Molecular Medicine, Justus-Liebig-UniversityGiessen

Positions:1997-1999: Post-Doc and Project Co-leader, SFB 547

“Cardiopulmonary Vascular System”, JLU Giessen1999-2004: Assistant Professor of Experimental Lung Research;

Justus-Liebig-University Giessen2005-recent: Head, Laboratory for Experimental Lung Research,

Hannover School of Medicine

Major research interests:Pathobiology of mononuclear phagocytes in acute and chronic lung

infections

Selected Publications:Holschermann H, Durfeld F, Maus U, et al. Blood 88: 3837, 1996.Maus U, v. Grote K, Kuziel WA, et al. Am J Respir Crit Care Med

166:268, 2002.Maus U, Huwe J, Ermert L, et al. Am J Respir Crit Care Med 165: 95,

2002.Maus UA, Waelsch K, Kuziel WA, et al. J Immunol 170: 3273, 2003.Maus U, Srivastava M, Paton JC, et al. J Immunol 173: 1307, 2004.Srivastava M, Jung S, Wilhelm J, et al. J Immunol 175: 1884, 2005.Maus U, Janzen S, Wall G, et al. Am J Respir Cell Mol Biol 35: 227,

2006.Srivastava M, Meinders A, Steinwede K, et al. Cell. Microbiol. 9:738,

2007.

First name:Ulrich

Last name:Maus

Acad. Title:Priv.-Doz. Dr.

Address:OE 6875Hannover School of Medicine


Further information:www.mh-hannover.de/3053.html

Department and function:Professor, Senior Research Group leader

Education:1961 Dipl. chem.., University of Cologne, Germany1964 Ph.D. (Dr.rer.nat.), University of Cologne, Germany1971 Dr.rer.nat. habil., Venia legendi, University of Freiburg

i.Br. Germany Faculty of Biology

Positions:1965-67 Research Associate, Salk Institute for Biological

Studies, La Jolla, CA, USA (Fulbright Travel Scholar)1968-69 Postdoctoral Fellow, Max Planck Institute for Molecular

Genetrics, Beriln, Germany1970 Senior Research Assistant, Max Planck Institute for

Molecular Genetrics, Berlin, Germany1970 Visiting Scientist, Weizmann Institute, Rehovot, Israel1970-71 Visiting Scientist, Department of Genetics, Stanford

University Medical School, Stanford, CA1970-1980 Permanent Member, Basel Institute for Immunology,

Basel, Switzerland1980-2001 Director, Basel Institute for Immunology, Basel,

Switzerland2003- Senior Research Group Leader, Max Planck Institute for

Infection Biology, Berlin, Germany

Major research interests:The senior group will continue to work on some projects which were developed at the Basel Institute for Immunology and which have focused on the development of cells of the innate and adaptive from stem cells and early progenitors and which have studied the development of B-lymphocytes in greater details.

Selected Publications:Shimizu T, Mundt C, Licence S, Melchers F, Martensson IL. J Immunol. 2002; 168, 6286-93.Rolink AG, Schaniel C, Melchers F. Immunol Rev. 2002; 187, 87-95.Hoffmann R, Bruno L, Seidl T, Rolink AG, Melchers F. J Immunol. 2003; 170, 1339-53.Ohnishi K, Melchers F. Nat Immunol. 2003; 4, 849-56.Melchers F. Nat Rev Immunol. 2005; 5, 578-84.Melchers F, Rolink AR. Curr Top Microbiol Immunol. 2006;305:1-23.Melchers F. Immunity. 2006;25(6):864-7.

First name:Fritz

Last name:Melchers


Address:Max Planck Institute for Infection BiologyCampus Charité MitteSchumannstr. 21/2210117 Berlin, Germany


Further information:http://www.mpiib-berlin.mpg.de/

Department and function:Associate Professor, Virology

Education:1990 PhD in Biology (Genetics), Eberhard Karls-University

Tübingen2002 Habilitation in Experimental Virology,

Ludwig Maximilians-University München

Positions:1991-1994: Postdoc at the Department of Virology, University

of Ulm and Department of Haematology and Oncology, University of Freiburg

1995-2001: Research Group Leader at the Department of Virology, University of Heidelberg and at the Max von Pettenkofer-InstituteLudwig-Maximilians-University München

2001-2004: Leader of the Virus-Cell-Interaction Unit at the Medical Faculty, University of Halle-Wittenberg

since 2005: Professor of Molecular Virology, Hannover Medical School

Major research interests:Analysis of viral proteins involved in the interaction of herpesviruseswith their host cellsImmunomodulation by herpesvirusesDevelopment of viral vectors for gene transfer, vaccination and tumortherapy

Selected Publications:Messerle M., Crnkovic I., Ziegler H., Hammerschmidt W., Koszinowski U.H. Proc. Natl. Acad. Sci. 1997; 94:14759-14763.Borst E., Hahn G., Koszinowski U.H., Messerle M. J. Virol. 1999; 73:8320-8329. Borst E., Mathys S., Wagner M., Muranyi W., Messerle, M. J. Virol. 2001; 75:1450-1458.Mathys S., Schroeder T., Ellwart J., Koszinowski U.H., Messerle M., Just U. J. Inf. Dis. 2003; 187:988-999.Borst E., Messerle M. Hum. Gene Ther. 2003; 14:959-970. Loewendorf A., Krueger C., Borst E., Wagner M., Just U., Messerle M. J. Virol. 2004; 78:13062-13071.Borst E., Messerle, M. J. Virol. 2005; 79(6):3615-26.Gustems M, Borst E, Benedict CA, Perez C, Messerle M, Ghazal P, Angulo A. J Virol. 2006 Oct;80(19):9899-904.

First name:Martin

Last name:Messerle




Further information:www.mh-hannover.de/institute/virologie/home.html

Department and function:Group Leader Molecular Genetic Diagnostics

Education:1988-1994 Study of marine biology, University of Kiel

Main focus: marine pathology1994 Thesis at Robert Koch Institut Berlin (AIDS Zentrum)1999 PhD in cell biology, University of Kiel

Positions:1994-2000: Group Leader, Stem Cell Transplantation Unit of the II.

Medical Clinic, University of Kiel2001 Head of Molecular Genetic Diagnostics, Institute of Cell

and Molecular Pathology, Hannover Medical School

Major research interests:- Modification of steroid resistance in childhood leukemia (ALL)

by differentially expressed peptides and proteins- Mesenchymal stem cells and wnt-pathway regulation

Selected Publications:von Neuhoff N, Kaiser T, Wittke S, Krebs R, et al. Rapid Commun. Mass Spectrom2004; 18: 149-156Janke, V., von Neuhoff, N., Schlegelberger, B., Leyhausen, G., Geurtsen, W. Biomaterials. 2004; 25(19):4573-80.Ritgen M, Stilgenbauer S, von Neuhoff N, Humpe A, et al. Blood. 2004; 104:2600-2.Rudolph C, Steinemann D, von Neuhoff N, Gadzicki D, et al. Cancer Genet Cytogenet. 2004; 153(2):144-50.Cario G, Stanulla M, Fine BM, Teuffel O, Neuhoff NV, et al. Blood. 2005; 105(2):821-6.Dammann CE, Meyer M, Dammann O, von Neuhoff N. Biol Neonate. 2006; 89(2):126-32Lauten M, Schrauder A, Kardinal C, Harbott J, Welte K, Schlegelberger B, SchrappeM, von Neuhoff N. Leukemia. 2006;20(5):820-6.

First name:Nils

Last name:von Neuhoff




Further information:www.mh-hannover.de/institute/zellpathologie

Department and function:Head, Biotechnology; FAL

Education:1973-1978 Veterinary Sciences, Veterinary University Hannover1978-1980 PhD thesis1985/86 Texas A&M University, College of Veterinary

Medicine1989: Habilitation Veterinary University Hannover1994: Apl. Professor for Reproductive Biology Veterinary

University Hannover

Positions:1980-1987: Scientist at the Institute for Animal Science1987-now: Head of Dept. Biotechnology at the Institute

Major research interests:Molecular regulation of preimplantation developmentTransgenesis in domestic species, Use of agricultural animals forbiomedical applications, Aspects of somatic cloningGenetic diversity

Selected Publications:Wrenzycki C, Herrmann D, Lucas-Hahn A, Korsawe K, Lemme E, Niemann H.Reprod Fertil Dev. 2005; 17(1-2):23-35.Kues WA, Carnwath JW, Niemann H. Reprod Fertil Dev. 2005;17(1-2):125-34.Yadav PS, Kues WA, Herrmann D, Carnwath JW, Niemann H. Mol Reprod Dev. 2005;72(2):182-90.Holker M, Petersen B, Hassel P, Kues WA, Lemme E, Lucas-Hahn A, Niemann H.Cloning Stem Cells. 2005;7(1):35-44.Somfai T, Dinnyes A, Sage D, Marosan M, Carnwath JW, Ozawa M, Kikuchi K, Niemann H. Theriogenology. 2006;66(2):415-22.Gebert C, Wrenzycki C, Herrmann D, Groger D, Reinhardt R, Hajkova P, Lucas-Hahn A, Carnwath J, Lehrach H, Niemann H. Genomics. 2006;88(2):222-9Kues WA, Schwinzer R, Wirth D, Verhoeyen E, Lemme E, Herrmann D, Barg-Kues B, Hauser H, Wonigeit K, Niemann H. FASEB J. 2006;20(8):1200-2.Ehling C, Rath D, Struckmann C, Frenzel A, Schindler L, Niemann H. Theriogenology. 2006;66(9):2160-4.Kues WA, Ollhoff RD, Carnwath JW, de Souza FP, Madeira HM, Niemann H. J Anim Breed Genet. 2006;123(5):326-30.Wrenzycki C, Herrmann D, Gebert C, Carnwath JW, Niemann H. Methods Mol Biol. 2006;348:285-304.Horn PA, Tani K, Martin U, Niemann H. Cloning Stem Cells. 2006;8(3):124-9Schwarzer M, Carnwath JW, Lucas-Hahn A, Lemme E, Kues WA, Wachsmann B, Haverich A, Martin U, Niemann H. Cloning Stem Cells. 2006;8(3):150-8.

First name:Heiner

Last name:Niemann

Acad. Title:Prof. Dr. med.vet. Dr.habil.

Address:Dept. BiotechnologyInstitute for Animal Science, MarienseeFAL, Hoeltystr. 1031535 Neustadt

Phone and e-mail:++49-(0)[email protected]

Further information:www.tzv.fal.de

Department and function:Department of Cellular ChemistryJunior Professor

Education:1994 PhD in Biochemistry at Lille Universiy, France

Positions:1995-1996: Postdoctoral position at University College London, UK1997-1999: Postdoctoral position at University of Dundee, UK2000: Maternity break2001: Marie Curie Fellow at Wageningen Research Center,

The Netherlands2002: Research Scientist, Cellular Chemistry, Hannover

Medical School2003- present: Junior Professor in Parasitology

Cellular Chemistry, Hannover Medical School

Major research interests:Analysis of the glycosylation pathways of eukaryotic pathogenssuch as the parasite Leishmania major and the fungus AspergillusfumigatusGalactofuranose metabolism; Nucleotide sugar transportersDesign and testing of drug leads in collaboration with other laboratories

Selected Publications:Ashikov A, Routier FH, Fuhlrott J, Helmus Y, Wild M, Gerardy-Schahn R, Bakker H. J Biol Chem 2005; 280(29), 27230-27235 Higson AP, Ross AJ, Tsvetkov YE, Routier FH, Sizova OV, Ferguson MA, NikolaevAV. Chemistry 2005, 11 (7), 2019-2030.Routier FH, Bakker H, Oelmann S, Jordi W, Lommen A, Gerardy-Schahn R, Bosch D. Glycobiology 2005: 15(2), 193-201.Tiralongo J, Ashikov A, Routier FH, Eckhardt M, Bakker H, Gerardy-Schahn R, von Itzstein M. Glycobiology 2006; 16(1), 73-81Bakker H, Kleczka B, Gerardy-Schahn R, Routier FH. Biol Chem 2005;386(7), 657-661.Kleczka B, Lamerz AC, van Zandbergen G, Wenzel A, Gerardy-Schahn R, Wiese M, Routier FH. J Biol Chem. 2007 Feb 6; [Epub ahead of print]

First name:Françoise

Last name:Routier




Further information:www.mh-hannover.de/institute/zellulaere_ chemie

Department and function:Department of Gastroenterology, Hepatology and EndocrinologyTeam Leader

Education:1997 Medical Doctor, Georg-August-University Göttingen2003 Habilitation in Experimental Gastroenterolgy, MHH

Positions:1998-2000: Postdoc with RA DePinho:

1. Albert-Eonsytein-college of Medicine, Bronx, New York2. Dana Faber Cancer Institute, Boston, MA

2001: Research Group Leader on Senescence, Aging and Carcinogenesis funded by the Emmy-Noether-Program of the DFG

Major research interests:1. Exploring the role of telomere shortening in A) Senescence, Aging, and Regeneration and B) Induction of chromosomal instability and Cancer2. Identification of organ and tissue specific Aging Markers3. Exploring new model organisms for aging research

Selected Publications:Rudolph KL, Chang S, Millard M, Schreiber-Agus N, DePinho RA. Science 2000; 287:1253-8. Rudolph KL, Millard M, Bosenberg MW, DePinho RA. Nat Genet. 2001; 28:155-9.Wiemann SU, Satyanarayana A, Tsahuridu M, Tillmann HL, et al. FASEB J. 2002;16:935-42.Satyanarayana A, Wiemann SU, Buer J, Lauber J, et al. EMBO J. 2003; 22:4003-4013 Satyanarayana A, Greenberg RA, Schaetzlein S, Buer J, et al. MCB 2004; 24:5459-74.Schaetzlein S, Lucas-Hahn A, Lemme E, Kues WA, et al. PNAS 2004; 101:8034-8.Wiemann SU, Satyanarayana A, Buer J, Kamino K, et al. Oncogene 2005; 24(9):1501-9.Lechel A, Satyanarayana A, J u Z, Plentz RR, et al. EMBO Rep. 2005; 6(3):275-81Schaetzlein S, Rudolph KL. Reprod Fertil Dev. 2005;17(1-2):85-96.Plentz RR, Lankisch TO, Basturk M, Muller CC, Kirchhoff T, Gebel M, Bleck JS, Kubicka S, Manns MP, Meier PN, Rudolph KL. J Gastroenterol Hepatol. 2005; 20(7):1134-6.Plentz RR, Tillmann HL, Kubicka S, Bleck JS, Gebel M, Manns MP, Rudolph KL. J Gastroenterol Hepatol. 2005; 20(9):1422-8.Djojosubroto MW, Chin AC, Go N, Schaetzlein S, Manns MP, Gryaznov S, Harley CB, Rudolph KL. Hepatology. 2005; 42(5):1127-36.Choudhury AR, Ju Z, Djojosubroto MW, Schienke A, Lechel A, Schaetzlein S, Jiang H, Stepczynska A, et al. Nat Genet. 2007 Jan;39(1):99-105.

First name:K. Lenhard

Last name:Rudolph




Department and function:Junior Professor of Molecular Hematology

Education:1997 PhD in Chemistry (Biological Chemistry), Johann

Wolfgang Goethe-University in Frankfurt/Main2002 Habilitation in Molecular Biology, Hannover Medical

School

Positions:1997-1998: Post-doc at the Beckman Research Institute of the City

of Hope, Dept. of Molecular Biology1998-2002 Post-doc at the Hannover Medical School, Dept. of

Hematology and Oncology2002-current: Junior Professor of Molecular Hematology at the

Hannover Medical School, Dept. of Hematology and Oncology

Major research interests:Gene silencing mediated by RNA interference (RNAi): functionalgenomics and therapeutic optionsLentiviral gene transfer into hematopoietic stem and precursor cells

Selected Publications:Scherr M., Battmer K., Blömer U., Schiedlmeier B., Ganser A., Grez M., Eder M. Blood 2002; 99: 709-712.Scherr M., Battmer K., Ganser A., Eder M. Cell Cycle 2003; 2: 251-257.Scherr M., Battmer K., Winkler T., Heidenreich O., Ganser A., Eder M. Blood 2003;101:1566-1569.Scherr M., Battmer K., Dallmann I., Ganser A., Eder M. Oligonucleotides 2003; 13: 353-363.Scherr M., Battmer K., Schultheis B., Ganser A., Eder M. Gene Ther 2005; 12: 12-21.Eder M, Scherr M. N Engl J Med. 2005; 352(23):2446-8.Scherr M, Chaturvedi A, Battmer K, Dallmann I, Schultheis B, Ganser A, Eder M. Blood. 2006;107(8):3279-87.Venturini L, Eder M, Scherr M. J Biomed Biotechnol. 2006;2006(4):87340.Venturini L, Battmer K, Castoldi M, Schultheis B, Hochhaus A, Muckenthaler MU, Ganser A, Eder M, Scherr M. Blood. 2007 Feb 6; [Epub ahead of print]

First name:Michaela

Last name:Scherr




Further information:www.mh-hannover.de/kliniken/haemonko/AK_Scherr/index1.html

Department and function:Professor, Cardiology and Angiology

Education:1984-1990 Medical School, Albert Ludwigs

University Freiburg i. Br.1987-1990 Doctoral thesis: Role of the Renin-

Angiotensin System in Experimental Heart Failure.1992-1993 Clinical Residency, Dept. of Cardiology,

Freiburg, University Hospital1993-1996 Postdoc, Dept. Of Experimental

Pathology, EMORY University Atlanta, USA.1996- Dept. Of Cardiology and Angiology, MHH

Positions:1992-1993 Clincial Residency1993-1996 Post-doc1996-1999 Clinical Residency1999-2001 Research Associatesince 2001 Assistant Prof. of Medicine

Major research interests:Vascular biology and Signal transduction of G-Protein coupledreceptors. Experimental and clinical atherosclerosis research

Selected Publications:Grote K, Drexler H, Schieffer B. Nephrol Dial Transplant. 2004; 19(4):770-3.Schieffer B, Bunte C, Witte J, Hoeper K, Boger RH, Schwedhelm E, Drexler H. J Am Coll Cardiol. 2004; 44(2):362-8Grote K, Bavendiek U, Grothusen C, Flach I, Hilfiker-Kleiner D, Drexler H, Schieffer B. J Biol Chem. 2004; 279(53):55675-81Schmidt B, Drexler H, Schieffer B. Am J Cardiovasc Drugs. 2004; 4(6):361-8.Schieffer B, Selle T, Hilfiker A, Hilfiker-Kleiner D, et al. Circulation. 2004; 110(22):3493-500Luchtefeld M, Grote K, Grothusen C, Bley S, Bandlow N, Selle T, Struber M, Haverich A, Bavendiek U, Drexler H, Schieffer B. Biochem Biophys ResCommun. 2005; 328(1):183-8.Grothusen C, Bley S, Selle T, Luchtefeld M, Grote K, Tietge UJ, Drexler H, Schieffer B. Atherosclerosis. 2005; 182(1):57-69.Grote K, Luchtefeld M, Schieffer B. Vascul Pharmacol. 2005;43(5):357-63.Grote K, Ortmann M, Salguero G, Doerries C, Landmesser U, Luchtefeld M, Brandes RP, Gwinner W, Tschernig T, Brabant EG, Klos A, Schaefer A, DrexlerH, Schieffer B. Cardiovasc Res. 2006 Aug 1;71(3):596-605.Luchtefeld M, Bandlow N, Tietge UJ, Grote K, Pfeilschifter J, Kaszkin M, Beck S, Drexler H, Schieffer B. Atherosclerosis. 2006 Oct 25; [Epub ahead of print]

First name:Bernhard

Last name:Schieffer



Phone and e-mail:++49-511-532 4666++49-511-532 [email protected]

Further information:www.mh-hannover.de/ kliniken/kardiologie/htm/ home.html

Department and function:Director, Cell and Molecular Pathology

Education:1975-1982 Studied medicine at the Ludwig Maximilian University

in Munich and the Christian Albrecht University of Kiel

Positions:1983-2000 Assistant, University Lecturer, then Professor at the

Institute of Human Genetics, University of Kiel1987-2000 Deputy Director of the Institute of Human Genetics,

University of Kiel2001- Director of the Institute of Cell and Molecular

Pathology, Hannover Medical School

Major research interests:My main interests are tumor genetics, with particular emphasis on thedissection of tumorigenesis, development of new diagnostic tools, and on genetic counseling in hereditary cancer syndromes.

Selected Publications:Wilkens L, Flemming P, Gebel M, Bleck J, Terkamp C, et al. Proc Natl Acad SciUSA. 2004;101(5):1309-14. Neuhoff N, Kaiser T, Wittke S, Krebs R, et al. Rapid Commun Mass Spectrom. 2004; 18(2):149-56Zhang Y, Zeleznik-Le N, Emmanuel N, Jayathilaka N, et al. Genes Chromosomes Cancer. 2004; 41(3):257-65. Rudolph C, Steinemann D, Von Neuhoff N, Gadzicki D, et al. Cancer Genet Cytogenet. 2004; 153(2):144-50.Gadzicki D, von Neuhoff N, Steinemann D, Just M, Busche G, Kreipe H, et. al. Cancer Genet Cytogenet. 2005;159(2):164-7.Wilkens L, Gerr H, Gadzicki D, Kreipe H, Schlegelberger B. Virchows Arch. 2005; 447(3):586-92.Rudolph C, Hegazy AN, von Neuhoff N, Steinemann D, et al. Cancer Genet Cytogenet. 2005; 161(1):51-6.Rudolph C, Liehr T, Steinemann D, Emura M, Daibata M, Matsuo Y, et al. CytogenetGenome Res. 2006;112(3-4):213-21.Staal FJ, Cario G, Cazzaniga G, Haferlach T, et al. Leukemia. 2006;20(8):1385-92.Balakrishnan A, von Neuhoff N, Rudolph C, Kamphues K, et al. Genes Chromosomes Cancer. 2006;45(10):883-92Rudolph C, Bittner C, Feller AC, Merz H, Schlegelberger B. Cytogenet Genome Res. 2006;114(3-4):292-5.Gohring G, Hanke C, Kratz C, Kontny U, et al. Ann Hematol. 2006;85(12):883-5.Gadzicki D, Baumer A, Wey E, Happel CM, et al. Ann Hum Genet. 2006;70(Pt 6):958-64.

First name:Brigitte

Last name:Schlegelberger

Acad. Title:Prof. Dr..



Further information:www.mh-hannover.de/institute/zellpathologie/

Department and function:Director, Clinical ImmunologyChairman of the MD/PhD Program

Education:1976 M.D., Medical School of the Rheinische Friedrich-

Wilhelms-Universität Bonn1977 Masters of Psychology, Rheinische Friedrich-Wilhelms-

Universität Bonn

Positions:1978-83 Instructor in Medicine, Medical School of the University

of Bonn1986-94 Associate Professor of Medicine and Immunology,

Hannover Medical School1995- Head, Professor of Medicine and Immunology, Dept.

Clinical Immunology, Hannover Medical School

Major research interests:Fc receptors, regulation and activation, role in pathogenesis of diseases; activation mechanisms of human natural killer cells; pathogenesis of vasculitis and chronic rheumatoid arthritis; immunotherapy (cytokinesand immunoglobulins); immunodeficiencies, AIDS - pathogenesis and treatment; clinical therapy studies

Selected Publications:Jacobs R, et al. J Clin Immunol. 2004; 24(3):281-6Momot T, et al. Arthritis Rheum. 2004; 50(5):1561-5Stoll M, et al. Autoimmun Rev. 2004; 3(4):243-9Tillmann HL, et al. AIDS Care. 2004; 16(6):736-43Jacobs R, et al. Mol Immunol. 2005; 42(2):239-49Skokowa J, et al. J Immunol. 2005; 174(5):3041-50.Koch S, et al. Genes Immun. 2005; 6(5):445-7.Mobius U, et al. J Acquir Immune Defic Syndr. 2005; 39(2):174-80.Rihl M, et al. J Infect. 2005 Nov 4;Kumar V, et al. J Clin Invest. 2006; 116(2):512-20.Momot T, et al. J Rheumatol. 2006;33(5):1029.Kittner JM, et al. J Clin Immunol. 2006; 26(4):400-5.Konrad S, et al. Br J Haematol. 2006;134(3):345-7.Ansari AW, et al. Int Immunol. 2006;18(10):1443-51.Wendt K, et al. J Leukoc Biol. 2006; 80(6):1529-41.

First name:Reinhold Ernst

Last name:Schmidt




Further information:www.mh-hannover.de/kliniken/immunwww-mh-hannover.de/studium/phd

Department and function:Director, Human Genetics

Education:1966-1973 Universities of Freiburg and Basel, Medicine

Positions: 1988-1990 Professor of Human Genetics, Berlin1990- Professor of Human Genetics, Director and Chair,

MHH

Major research interests:Molecular Basis of Inherited Disease, Genetics of Behavior in Subhuman Primates, Structure and Ethics of Genetic Service Provision

Selected Publications:Rommel, Karck, Haverich, Schmidtke, Arslan-Kirchner, Hum. Mutat 2002; 20: 406Schubert S, Skawran B, Dechend F, Nayernia K, Meinhardt A, et al. Biol Reprod. 2003; 69(3):968-75.Pabst B, Arslan-Kirchner M, Schmidtke J, Miller K. Cytogenet Genome Res. 2003; 103(1-2):3-7Schmidtke J, Kuhnau W, Wand D, Edelmann J, Szibor R, Krawczak M PrenatDiagn. 2004; 24(8):662-4.Stuhrmann M, Strassburg C, Schmidtke J. Eur J Hum Genet. 2005; 13(1):69-78Krawczak M, Trefilov A, Berard J, Bercovitch F, et al. Biol Reprod. 2005; 72(5):1109-13.Singh KK, Schmidtke J. Immunogenetics. 2005; 57(3-4):289-92.Skawran B, Schubert S, Dechend F, Vervoorts J, Nayernia K, Luscher B, Schmidtke J. Mol Cell Biochem. 2005; 276(1-2):159-67.Singh KK, Ristau S, Dawson WW, Krawczak M, Schmidtke J. Exp Eye Res. 2005; 81(4):401-6.Trefilov A, Croucher PJ, Krawczak M, Schmidtke J. Twin Res Hum Genet. 2005; 8(6):551-2.Singh KK, Shukla PC, Rommel K, Schmidtke J, Arslan-Kirchner M. Eur J HumGenet. 2006;14(7):876-9.Karwacki V, Kovac J, Mauceri G, Backhaus A, Fohse L, Schmidtke J, Schubert S.Genomics. 2006;88(1):65-73.Singh KK, Rommel K, Mishra A, Karck M, Haverich A, Schmidtke J, Arslan-Kirchner M. Hum Mutat. 2006;27(8):770-7.Stuhrmann M, Nippert I, Hoy L, Schmidtke J. Clin Genet. 2006;70(1):73-7.Singh KK, Elligsen D, Liersch R, Schubert S, Pabst B, Arslan-Kirchner M, Schmidtke J. J Mol Cell Cardiol. 2007;42(2):352-6.

First name:

Jörg

Last name:

Schmidtke


Address: OE 6300Hannover Medical School


Further information:www.human-genetik.net

Department and function:Director, Virology

Education:1980 MD Mainz1986 Habilitation Innsbruck

Positions:1996 MRCPath, London, 2003 FRCPath, London, 2004- Virology, MHH

Major research interests:Kaposi‘s sarcoma – associated herpesvirus/human herpesvirus 8

Selected Publications:Greensill J, Sheldon J, Renwick NM, Beer B, Norley S, et al. J. Virol. 2000; 74:1572-1577.Luppi M, Barozzi P, Schulz TF, et al. N Engl J Med 2000; 343: 1378-1385Viejo-Borbolla A, Kati E, Sheldon J, Nathan K, Mattsson K, et al. J.Virol. 2003; 77(12):7093-100.Brinkmann MM, Glenn M, Rainbow L, Kieser A, Henke-Gendo C, Schulz TF. J Virol. 2003; 77(17):9346-58.Viejo-Borbolla A, Schulz TF. AIDS Rev. 2003; 5(4):222-9Henke-Gendo C, Schulz TF, Hoeper MM. N Engl J Med. 2004; 350(2):194-5Henke-Gendo C, Schulz TF. Curr Opin Infect Dis. 2004; 17(1):53-7Dedicoat M, Newton R, Alkharsah KR, Sheldon J, et al. J Infect Dis. 2004; 190(6):1068Viejo-Borbolla A, Pizzato M, Blair ED, Schulz TF. Virus Res. 2005;108(1-2):45-55.Viejo-Borbolla A, Thomas P, Blair ED, Schulz TF. J Gen Virol. 2005;86:2469-80.Henke-Gendo C, Mengel M, Hoeper MM, Alkharsah K, Schulz TF. Am J Respir CritCare Med. 2005; 172(12):1581-5.Viejo-Borbolla A, Ottinger M, Bruning E, Burger A, Konig R, Kati E, Sheldon JA, Schulz TF. J Virol. 2005; 79(21):13618-29.Alkharsah KR, Dedicoat M, Deluca DS, Schulz TF, Blasczyk R. Tissue Antigens. 2006; 67(2):170-2Ottinger M, Christalla T, Nathan K, Brinkmann MM, Viejo-Borbolla A, Schulz TF.J Virol. 2006;80(21):10772-86.Barozzi P, Bosco R, Vallerini D, Potenza L, Torelli G, Luppi M, Facchetti F, GuaraldiG, Schulz TF. Transplantation. 2006;82(6):851-2.Brinkmann MM, Pietrek M, Dittrich-Breiholz O, Kracht M, Schulz TF. J Virol. 2007; 81(1):42-58.Alkharsah KR, Dedicoat M, Blasczyk R, Newton R, Schulz TF. J Infect Dis. 2007; 195(6):809-16.

First name:

Thomas F.

Last name:Schulz

Acad. Title:Prof. Dr. med., FRCPath



Department and function:Group Leader, Transplant Laboratory

Education:1983 Degree of „Diplom-Biologe“ (Masters Degree in

Biology), University of Braunschweig

1987 Degree of „Dr.rer.nat.“ (PhD), University of Hannover

1994 Habilitation; Venia legendi for Immunology, Hannover Medical School (MHH)

Positions:1983-1987 Research Assistant, MHH

1987-1990 Research Associate, MHH

1990-1991 Fellowship of the German Research Council (DFG), National Jewish Center for Immunology, Denver

1991- Group leader, Transplant Laboratory, MHH

1999- Professor of Immunology

Major research interests:Transplant Immunology/Xenotransplantation: Analysis of human anti-pig T cell responses, development of immunomodulatory antibodies, immunological monitoring of transplant recipients.Analysis of T cell activation in the human: Signal transduction, role of cell surface molecules (CD28, CD45), CD45 polymorphisms.

Selected Publications:Siefken R, Klein-Heßling S, Serfling E, Kurrle R, Schwinzer R. J Immunol 1998; 161:1645-1651 Jacobsen M, Schweer D, Ziegler A, et al. Nature Gen 2000; 26:495-499Niemann H, Verhoeyen E, Wonigeit K et al. Transplantation 2001; 72:1898-906 Dulat H, von Grumbkow C, Baars W, Schröder N, Wonigeit K, Schwinzer R. Eur J Immunol 2001; 31: 2217-2226Schwinzer R, Witte T, Hundrieser J, et al. Genes Immun 2003; 4:168-169Bedke T, Baars W, Schwinzer R Ann Transplant. 2003; 8(3):35-8Do HT, Baars W, Schwinzer R. Transplant Proc. 2005; 37(1):51-2.Do HT, Baars W, Borns K, Windhagen A, Schwinzer R. J Immunol. 2006; 176(2):931-8.

First name:Reinhard

Last name:Schwinzer

Acad. Title:Prof. Dr.rer.nat.



Further information:www.mh-hannover.de/kliniken/visceralchirurgie/

Department and function:Gastroenterology, Hepatology & EndocrinologyAttending in medicine and GI, principal investigator

Education:1977 -1985 Study of Medicine at the Ludwig-

Maximilian‘s University, Munich1985 Doctoral thesis2000 Venia legendi for international medicine

Positions:1985 - 1987 Postdoc, Dept. of Pharmacology, MHH1987 – 1988 Postdoc., Dig. Dis Center, Beth Israel Hospital, Boston1988 – 1995 Resident in Internal medicine and GI, Technical

University of Munich1995 - 2002 Attending, GI Division, Eberhard-Karls University,

Tübingen

Major research interests:1.Structure-function relationsships and protein-protein interactions in the regulation of the transport proteins for intestinal salt absorption and anion secretion.2.Mechanisms of volume regulation in gastrointestinal cells.3.Adaptive mechanisms in the gastrointestinal tract after selectiveknockout of transport and regulator proteins which are important in gastrointestinal salt and nutrient transport.

Selected publications:Bachmann O, Rossmann H, Berger UV, Colledge WH, Ratcliff R, et al. Am. J.Physiol. 2003; 284(1):G37-45.Spiegel S, Phillipper M, Rossmann H, Riederer B, Gregor M, Seidler U. Am J PhysiolGastrointest Liver Physiol. 2003; 285(5):G887-97.Fahrmann M, Kaufhold M, Pfeiffer AF, Seidler U. Br J Pharmacol. 2003; 139:545-54Spiegel S, Phillipper M, Rossmann H, Riederer B, Gregor M, Seidler U. Am J PhysiolGastrointest Liver Physiol. 2003; 285(5):G887-97Bachmann O, Riederer B, Rossmann H, Groos S, et al. Am J Physiol GastrointestLiver Physiol. 2004; 287(1):G125-33.Schwab A, Rossmann H, Klein M, Dieterich P, Gassner B, Neff C, Stock C, Seidler U. J Physiol. 2005;568(Pt 2):445-58Tuo B, Riederer B, Wang Z, Colledge WH, Soleimani M, Seidler U. Gastroenterology. 2006;130(2):349-58Bachmann O, Reichelt D, Tuo B, Manns MP, Seidler U. Am J Physiol GastrointestLiver Physiol. 2006;291(4):G650-7.Bachmann O, Heinzmann A, Mack A, Manns MP, Seidler UE. Am J PhysiolGastrointest Liver Physiol. 2006 Nov 9; [Epub ahead of print]

First name:Ursula

Last name:Seidler




Further information:www.mh-hannover.de/ kliniken/gastro/gastro.htm

Department and function:Institute for Transfusion Medicine

Education:1996 MD, Friedrich-Alexander-University

Erlangen2002 Medical specialist in transfusion medicine2003 W1-Professor for molecular immunohematology

Positions:1996-1998: Intern, Clinic I for Internal Medicine, Clinical Center

Fuerth1998-2001: Resident, Department of Hematology, Oncology and

Blood Bank, Humboldt-University Berlin1997-2000: Resourch Group Leader, Institute for Transfusion

Medicine, Hanover Medical School, Hanover, Germany2003-recent: W1-Professor, Institute for Transfusion Medicine,

Hanover Medical School, Hanover, Germany

Major research interests:Molecular biology of erythrocyte proteinsDecreasing Immunogenicity of Progenitor Cells by Regulating MHC Expression

Selected Publications:Seltsam A, Hallensleben M, Kollmann A, Blasczyk R. Blood 2003; 102: 3035-42.Eiz-Vesper B, Seltsam A, Blasczyk R. Transfusion 2005; 45:960-8.Seltsam A, Das Gupta C, Wagner FF, Blasczyk R. Transfusion. 2005;45:359-65.Wagner FF, Blasczyk R, Seltsam A. Transfusion 2005;45:1331-4.Figueiredo C, Seltsam A, Blasczyk R. J Mol Med. 2006;84(5):425-37.Seltsam A, Das Gupta C, Bade-Doeding C, Blasczyk R. Transfusion. 2006;46(3):434-40.Figueiredo C, Horn PA, Blasczyk R, Seltsam A. Transfusion. 2007;47(1):18-27.Seltsam A, Strigens S, Levene C, Yahalom V, Moulds M, Moulds JJ, Hustinx H, Weisbach V, Figueroa D, Bade-Doeding C, Deluca DS, Blasczyk R. Transfusion. 2007 Jan;47(1):133-46.

First name:Axel

Last name:Seltsam

Acad. Title:Prof. Dr.med.



Further information:www99.mh-hannover.de/institute/transfusion/transfusionsmedizin/

Department and function:Assistant Professor, Virology

Education:1982 – 1988 University of Bonn, Biology1988 – 1989 Columbia University, New York, NY, USA

Immunology1989 - 1993 European Molecular Biology Laboratory, Heidelberg,

Cell Biology

Positions:1993 - 1997 Postdoc and Staff Scientist, Yale University,

New Haven, CT, USA, Dept. Cell Biology1997 – 2002 Group leader, Biochemistry Dept., MHH

Major research interests:Our group is interested in the cell biology of complex DNA viruses. How does a virus get access to a cell, disassemble to uncover its genome for replication, and how is – within a couple of hours – the viral program switched to virus assembly and egress? We have developed several in vivo and in vitro motility assays to analyse the cell biology of Herpes Simplex Virus and particularly the microtubule-mediated capsid transport by digital video microscopy. Using these assays, we characterize cytosolic host factors as well as structural viral proteins important in HSV1 entry and egress.

Selected Publications:Sodeik, Ebersold, Helenius. J of Cell Biology 1997; 136:1007-1021.Ojala, Sodeik, Ebersold, Kutay, Helenius. Mol & Cell Biology 2000; 20:4922-4931.Döhner, Wolfstein, Prank, Echeverri, Dujardin, Vallee, & Sodeik. Molecular Biology Cell 2002; 13:2795-2809.Mabit H, Nakano MY, Prank U, Saam B, Dohner K, et al. J Virol. 2002; 76(19):9962-71Sodeik B. J Cell Biol. 2002; 159(3):393-5.Marozin S, Prank U, Sodeik B. J Gen Virol. 2004; 85(Pt 4):775-86.Haas M, Siegert M, Schurmann A, Sodeik B, Wolfes H. Biochemistry. 2004; 43(25):8152-9.Dohner K, Sodeik B. Curr Top Microbiol Immunol. 2005;285:67-108.Wolfstein A, Nagel CH, Radtke K, Dohner K, Allan VJ, Sodeik B. Traffic. 2006; 7(2):227-37Radtke K, Dohner K, Sodeik B. Cell Microbiol. 2006; 8(3):387-400.Dohner K, Radtke K, Schmidt S, Sodeik B. J Virol. 2006;80(16):8211-24.

First name:Beate

Last name:Sodeik

Acad. Title:HD Dr. rer.nat.



Further information:www.mh-hannover.de/institute/virologie/

Department and function:Professor, Human Genetics

Education:1980 – 1986 Free University Berlin, Medicine1988 MD1995 Specialist in Human Genetics2002 apl. Professorship

Positions:1987 Guestdoc, Cerrahpasha Medical Faculty,

Istanbul, Turky1988 – 1990 Postdoc, Inst. Humangenetics, FU BerlinSince 1991 Head of Molecular Diagnostics, Inst. Human

Genetics, Medical School Hannover

Major research interests:Molecular genetics of several monogenenic disorders like cysticfibrosis, haemochromatosis, morbus Osler, ataxia telangiectasia; neuro-and psychiatro-genetics, genetic screening

Selected Publications:M.Schürmann, M.Albrecht, E.Schwinger, M.Stuhrmann. Eur J Hum Genet 2002;10:729-732Groman JD, Hefferon TW, Casals T, Bassas L, Estivill X, et al. Am J Hum Genet. 2004; 74(1):176-9.Gadzicki D, Muller-Vahl KR, Heller D, Ossege S, Nothen MM, Hebebrand J, Stuhrmann M. Am J Med Genet B Neuropsychiatr Genet. 2004; 127(1):97-103Grundmann K, Laubis-Herrmann U, Dressler D, Vollmer-Haase J, et al. Mov Disord. 2004; 19(11):1294-7.Stuhrmann M, Strassburg C, Schmidtke J. Eur J Hum Genet. 2005; 13(1):69-78.Kuehl HK, Caselitz M, Hasenkamp S, Wagner S, El-Harith el-HA, Manns MP, Stuhrmann M. Hum Mutat. 2005; 25(3):320.Stuhrmann M, Hoy L, Nippert I, Schmidtke J. Genet Test. 2005;9(3):242-54.Hildebrand F, Pape HC, Griensven M, Meier S, Hasenkamp S, Krettek C, StuhrmannM. Shock. 2005;24(6):518-22.Stuhrmann M, Nippert I, Hoy L, Schmidtke J. Clin Genet. 2006;70(1):73-7El-Harith el-HA, Kuhnau W, Schmidtke J, Gadzicki D, Ahmed M, Krawczak M, Stuhrmann M. Eur J Med Genet. 2006;49(4):323-30.Metzger S, Bauer P, Tomiuk J, Laccone F, Didonato S, Gellera C, Mariotti C, Lange HW, et al. Hum Genet. 2006;120(2):285-92

First name:Manfred

Last name:Stuhrmann-Spangenberg




Further information:www.mh-hannover.de/humangenetik.html

Department and function:Head, ‘Clinical Reasearch Group Pseudomonas‘

Education and positions:1971 - 1976 study of biochemistry1974 - 1981 study of medicine1979 Dr. rer.nat.1984 Dr. med.1991 habilitation1992 professorship

Major research interests:• Genomics• Molecular pathology of cystic fibrosis• Pseudomonas genomics

Selected Publications:Klockgether J, Reva O, Larbig K, Tummler B. J Bacteriol. 2004; 186(2):518-34.Mekus F, Tummler B Cystic fibrosis and NOS3. Am J Respir Crit Care Med. 2004; 169(2):319-2Mekus F, Tummler B. Am J Respir Crit Care Med. 2004;169(6):770Juhas M, Wiehlmann L, Huber B, Jordan D, et al. Microbiology. 2004; 150(Pt 4):831-41.Charizopoulou N, Jansen S, Dorsch M, Stanke F, Dorin JR, Hedrich HJ, Tummler B.BMC Genet. 2004; 5(1):6.Ritzka M, Stanke F, Jansen S, Gruber AD, et al. Hum Genet. 2004;115(6):483-91.Eberl L, Tummler B. Int J Med Microbiol. 2004; 294(2-3):123-31.

Juhas M, Wiehlmann L, Salunkhe P, Lauber J, Buer J, Tummler B. FEMS MicrobiolLett. 2005; 242(2):287-95.Salunkhe P, Topfer T, Buer J, Tummler B. Bacteriol. 2005; 187(8):2565-72.Reva ON, Tummler B. BMC Bioinformatics. 2005; 14;6:251.Stanke F, Becker T, Cuppens H, Kumar V, Cassiman JJ, Jansen S, Radojkovic D, Siebert B, Yarden J, Ussery DW, Wienker TF, Tummler B. Hum Genet. 2006;:1-13van Barneveld A, Stanke F, Ballmann M, Naim HY, Tummler B. Biochim BiophysActa. 2006;1762(4):393-7.Charizopoulou N, Wilke M, Dorsch M, Bot A, Jorna H, Jansen S, Stanke F, HedrichHJ, de Jonge HR, Tummler B. BMC Genet. 2006;7:18.Reva ON, Weinel C, Weinel M, Bohm K, Stjepandic D, Hoheisel JD, Tummler B.J Bacteriol. 2006;188(11):4079-92.Bragonzi A, Wiehlmann L, Klockgether J, Cramer N, Worlitzsch D, Doring G, Tummler B. Microbiology. 2006;152(Pt 11):3261-9.Klockgether J, Wurdemann D, Reva O, Wiehlmann L, Tummler B. J Bacteriol. 2006 Dec 28; [Epub ahead of print]Chang YS, Klockgether J, Tummler B. FEMS Microbiol Lett. 2007 Feb 13; [Epubahead of print]

First name:Burkhard

Last name:Tümmler

Acad. Title:Prof. Dr. Dr.



Further information:http://www. mh-hannover.de/ kliniken/kinderheilkunde/kfg/index.htm

Department and function: Director, Cell Biology

Education:1974: Diploma in Biology from the Free University Berlin1976: PhD obtained from the Free University Berlin1977-79: EMBO Fellow at the MRC Unit for Biophysics at

King‘s College in London, UK1979-82: Postdoctoral fellow (DFG) at the Biological

Laboratories at Harvard University (Cambridge, Ma)1982-84: Heisenberg-Fellow at the LMB in Cambridge (UK)

and the Max-Planck Institute for BiophysicalChemistry in Göttingen, Germany.

Positions:1986-92: Junior-Research group leader at the Max-Planck-

Institute for Biochemistry, Martinsried, Germany1992-1998: Associate Professor at the Dept. of pathology at

Washington University St. Louis, MOsince 1998: Professor for Cell Biology at MHH

Major research interests:Intracellular vesicular transport, functions of molecular chaperones

Selected Publications:Ungewickell, E., H. Ungewickell, et al. Nature 1995; 378: 632-635.Umeda, A., A. Meyerholz, et al. Eur J Cell Biol 2000; 79(5): 336-342.Scheele, U., C. Kalthoff, et al. J Biol Chem 2001; 276(39): 36131-36138.Kalthoff, C., S. Groos, et al. Mol Biol Cell 2002; 13(11): 4060-4073.Kalthoff, C., J. Alves, et al. J Biol Chem 2002; 277(10): 8209-8216.Scheele, U., J. Alves, et al. J Biol Chem. 2003; 278(28):25357-68.Hinrichsen, L., J. Harborth, et al. J Biol Chem. 2003; 278(46): 45160-70.Tsukada M, Prokscha A, Ungewickell E, Eichele G. J Biol Chem. 2005; 280(12):11361-8.Meyerholz A, Hinrichsen L, Groos S, Esk PC, Brandes G, Ungewickell EJ. Traffic. 2005; 6(12):1225-34.Hasse S, Ungewickell EJ, Groos S. Histochem Cell Biol. 2006;126(2):219-29Hinrichsen L, Meyerholz A, Groos S, Ungewickell EJ. Proc Natl Acad Sci U S A. 2006;103(23):8715-20.Duwel M, Ungewickell EJ. Mol Biol Cell. 2006;17(10):4513-25.

First name:Ernst

Last name:Ungewickell



Phone and e-mail: ++49-511- 532 [email protected]

Further information:www.mh-hannover.de/institute/zellbiologie/

Department and function:Head, Central Institute for Biophysical and BiochemicalProcedures

Education:1968-1972 Chemistry, Technical University Braunschweig1972 – 1976 Dissertation, University Hannover

Positions:1973- Hannover Medical School

Major research interests:Protein nucleic acid and protein protein interactions Single strandedDNA binding proteins, analytical ultracentrifugation, biophysicalchemistry in solution

Selected Publications:Urbanke C, Wray J. Biochem J 2001; 358:165-73 Grazulis S, Deibert M, Rimseliene R, Skirgaila R, Sasnauskas G, et al. NucleicAcids Res 2002; 30(4):876-85Meyer S, Urbanke C, Wahle E.. Biochemistry 2002 ;41(19):6082-9Landwehr M, Curth U, Urbanke C. Biol Chem 2002; 383(9):1325-33 Schubert WD, Urbanke C, Ziehm T, Beier V, Machner MP,et al. Cell 2002; 111(6):825-36Witte G, Urbanke C, Curth U. Nucleic Acids Res. 2003; 31(15):4434-40Zaremba M, Urbanke C, Halford SE, Siksnys V J Mol Biol. 2004; 336(1):81-92Dreisewerd K, Rohlfing A, Spottke B, Urbanke C, Henkel W. Anal Chem. 2004; 76(13):3482-91Hansen T, Urbanke C, Schonheit P Extremophiles 2004; 8(6):507-12Maheswaran M, Urbanke C, Forchhammer K. J Biol Chem. 2004; 279(53):55202-10Yildiz O, Doi M, Yujnovsky I, Cardone L, Berndt A, Hennig S, Schulze S, Urbanke C, Sassone-Corsi P, Wolf E. Mol Cell. 2005; 17(1):69-82.Brasen C, Urbanke C, Schonheit P. FEBS Lett. 2005; 579(2):477-82.Urbanke C, Witte G, Curth U. Methods Mol Biol. 2005;305:101-14.Zaremba M, Sasnauskas G, Urbanke C, Siksnys V. J Mol Biol. 2006;363(4):800-12.Manelyte L, Urbanke C, Giron-Monzon L, Friedhoff P. Nucleic Acids Res. 2006;34(18):5270-9.

First name:Claus

Last name:Urbanke




Further information:http://www.mh-hannover.de/einrichtungen/bpc/

Department and function:Head of Division of Cell Biology and Immunology, HZI

Education:1980 PhD in Cell Biology, Max-Planck-Institute for

Biophysical Chemistry, Göttingen; University Bonn1988 Habilitation in Cell Biology, University Bonn

Positions:1980-1982: Postdoc, National Cancer Institute, Bethesda,

USA (supported by EMBO fellowship)1983-1989: Research Assistant, Dept. of Biochemistry and Cell

Biology, Max-Planck-Institute for Biophysical Chemistry, Göttingen

1989-1993: Research Assistant, Project Leader in Dept. of Microbiology, HZI, Braunschweig

1994-1997: Acting head of the Division of Cell Biology and Immunology, HZI, Braunschweig

Since 1997: Full Professor (C4) for Cell Biology and Immunology, Technical University Braunschweig;Head of the Division of Cell Biology and Immunology, HZI, Braunschweig

Major research interests:Analysis of mechanisms of host/pathogen interactions signalling to the actin cytoskeleton; actin dynamics and cell motility.

Selected Publications:Lommel, S., Benesch, S., Rottner, K., Franz, T., Wehland, J. & Kühn, R. EMBO reports 2001; 2: 850-857.Schubert, W.-D., Urbanke, C., Ziehm, T., Beier, V., Machner, M., Domann, E., Wehland, J., Chakraborty, T. & Heinz, D.W. Cell 2002; 111: 825-836.Steffen, A., Rottner, K., Ehinger, J., Innocenti, M., Scita, G., Wehland, J., Stradal, T. E. EMBO J. 2004; 23(4):749-59Erck C, Peris L, Andrieux A, Meissirel C, Gruber AD, Vernet M, Schweitzer A, Saoudi Y, Pointu H, Bosc C, Salin PA, Job D, Wehland J. Proc Natl Acad Sci U S A. 2005; 102(22):7853-8.Dieterich G, Karst U, Fischer E, Wehland J, Jansch L. Nucleic Acids Res. 2006; 34(Database issue):D402-6.Jenzora A, Behrendt B, Small JV, Wehland J, Stradal TE. FEBS Lett. 2006; 580(12):455-63.Baumgartner M, Karst U, Gerstel B, Loessner M, Wehland J, Jansch L. J Bacteriol. 2007;189(2):313-24.Thedieck K, Hain T, Mohamed W, Tindall BJ, Nimtz M, Chakraborty T, Wehland J, Jansch L. Mol Microbiol. 2006;62(5):1325-39.

First name:Jürgen

Last name:Wehland


Address:Helmholtz Center forInfection Research (HZI)Braunschweig



Department and function: Head, Molecular Immunology, HZI

Education:1969-1978 Biology at the Free University of Berlin,

Special Studies: Molecular Biology and Genetics1974-1978 PhD Student at the Basel Institute for Immunology,

Basel, Switzerland

Positions:1978-1980 Research Associate at the Salk Institute for Biological

Studies, Department of Developmental Biology, San Diego,USA.

1980-1983: Scientific Assistant at the Friedrich-Miescher-Laboratorium of the Max-Planck-Gesellschaft, Tübingen, Germany.

1983-1989: Member at the Basel Institute for Immunology, Basel, Switzerland.

1989-1990: Visiting Professor at the Institute for Immunology and Rheumatology, University of Oslo, Oslo, Norway.

1990-present: Group leader at the HZI (Helmholtz Center for InfectionResearch), Braunschweig, Germany.

Major research interests:Interaction of bacteria with the immune system.B cell development.

Selected PublicationsLoessner H, Weiss S Expert Opin Biol Ther. 2004; 4(2):157-68Gekara NO, Weiss S. Biochem Soc Trans. 2004; 32(Pt 5):712-4.Zelmer A, Krusch S, Koschinski A, Rohde M, Repp H, Chakraborty T, Weiss S. J Gene Med. 2005; 7(8):1097-112.Samuelsson CV, Lienenklaus S, Muller PP, Zawatzky R, Hauser H, Weiss S. BiochemBiophys Res Commun. 2005; 335(2):584-9.Gekara NO, Jacobs T, Chakraborty T, Weiss S. Cell Microbiol. 2005;7(9):1345-56.Bruder D, Nussbaum AK, Gakamsky DM, Schirle M, Stevanovic S, Singh-Jasuja H, Darji A, Chakraborty T, Schild H, Pecht I, Weiss S. Int Immunol. 2006;18(1):89-100.Loessner H, Endmann A, Rohde M, Curtiss R 3rd, Weiss S. FEMS Microbiol Lett. 2006;265(1):81-8.Jablonska J, Dittmar KE, Kleinke T, Buer J, Weiss S. Infect Immun. 2007;75(1):462-70.Becker C, Lienenklaus S, Jablonska J, Bauer H, Weiss S. J Mol Med. 2007;85(1):63-73.Loessner H, Endmann A, Leschner S, Westphal K, Rohde M, Miloud T, HammerlingG, Neuhaus K, Weiss S. Cell Microbiol. 2007 Feb 7; [E pub ahead of print]

First name:Siegfried

Last name:Weiss

Acad. Title:Dr. rer.nat.

Address:AG MolekulareImmunologie,Mascheroder Weg 1a,38124 Braunschweig

Phone and e-mail:++49-0531-6181-230, [email protected]

Further information:http://www.helmholtz-hzi.de/de/forschergruppen/molekulare_biotechnologie/molekulare_immunologie/team/personal/infos/siegfried_weiss/

Department and function:Hematology, Hemostasis and OncologyScientist (bone marrow transplantation; Experimental Hematology)

Education:1987: MD Medical Faculty, University of Vienna, Austria1997: Habilitation in Experimental Hematology, Ludwig-

Maximillians-Universität / Munich2005: APL-Professor/ Experimental Hematology

Positions:1989-1992: Visiting fellow at the National Institutes of Health, NCI, Laboratory of Genetics1992-1993: Visiting associate (NIH/NCI/LG)1993-1998: Junior group leader GSF / Hämatologikum / Munich1998-1999: Invited scientist NIH/ National Heart/Lung/Blood

Institute1999-2002: Scientific and clinical staff fellow MHH/ Hematology2002-2003: Chief medical officer mosaiques diagnostics GmbH2003- recent: Scientific group leader MHH/ Hematology

Major research interests:Gene therapy of Graft versus Host diseaseStem Cell Transplantation: experimental and clinical applicationAntigen-specific T-cells : therapeutic and researchProteomics in clinical research and diagnosis

Selected Publications:Bonini, C., Grez, M., Traversari, C., et al., Nature Med 2003; 9: 367-369Weissinger E.M., Oettrich K., Evans C., Genieser H.G., Schwede F., Dangers M., Dammann E., Kolb H.J., Mischak H., Ganser A., Kolch W. Br J Cancer 2004; 91:186-92Weissinger, E.M., Wittke, S., Kaiser, et al. Kidney Int. 2004; 65: 2426-2434Kaiser T., Kamal H., Rank A., Kolb H.J., Holler E., Ganser A., Hertenstein B., Mischak H., Weissinger E.M. Blood 2004; 104: 340-349Weissinger, E.M., Mischak, H. Transplant Med.2004; 16:1-5Weissinger EM, Oettrich K, Evans C, Genieser HG, Schwede F, Dangers M, Dammann E, Kolb HJ, Mischak H, Ganser A, Kolch W. Br J Cancer. 2004;91(1):186-92.Weissinger EM, Nguyen-Khoa T, Fumeron C, Saltiel C, Walden M, Kaiser T, Mischak H, Drueke TB, Lacour B, Massy ZA. Proteomics. 2006;6(3):993-1000.Weissinger EM, Mischak H, Ganser A, Hertenstein B. Ann Hematol. 2006;85(4):205-11Ganser A, Morgan MA, Weissinger EM. Proc Natl Acad Sci U S A. 2007; 104(4):1109-10.

First name:Eva

Last name:Mischak-Weissinger

Acad. Title:Prof. Dr.med univ.



Further information:www.mh-hannover.de/kliniken/haemonko

Department and function:Director, Pediatric Hematology/Oncology

Education:1969-1973 University Tübingen, Medicine1973-1975 Freie Universität Berlin1975 Dr. med.1976 Approbation1984 Board certified Pediatrician

Positions:1985-1987 Assist. Professor, Head Laboratory of

Cytokine Biology, Memorial Sloan KetteringCenter, New York

1987-1993 Professor for Pediatrics, MHH1993-1997 Professor for Specific Pediatric Hematology

and Oncology, MHHSince 1997 Head, Dept. of Pediatric Hematology/

Oncology, MHH

Major research interests:Cytokines, Hematopoietic stem cells, Bone marrow failuresyndromes, Leukemias

Selected Publications:Ballmaier M, et al. Ann N Y Acad Sci. 2003; 996:17-25.Beger C, et al. Br J Haematol. 2003; 122(2):245-52.Lauten M, et al. Leukemia. 2003; 17(8):1551-6Lauten M, et al. Haematologica. 2003; 88(11):1253-8.Zeidler C, et al. Rev Clin Exp Hematol. 2003; 7(1):72-83.Beger C, et al. Clin Cancer Res. 2004; 10(11):3780-7.Meissner B, et al. Leukemia. 2004; 18(11):1920-3.Kracht T, et al. Haematologica. 2004; 89(12):1492-7Cario G, et al.. Blood. 2005; 105(2):821-6Cloppenborg T, et al. Leukemia. 2005; 19(1):44-8Stanulla M, et al. Blood. 2005;105(2):906-7Cario G, et al. Br J Haematol. 2005; 129(2):275-8.Wang Z, et al. Ann N Y Acad Sci. 2005; 1044:29-40.Kardinal C, et al. Blood. 2006 Feb 1;107(3):1133-40.Germeshausen M, et al. Hum Mutat. 2006; 27(3):296.Skokowa J, et al. Nat Med. 2006;12(10):1191-7.Germeshausen M, Ballmaier M, Welte K. Blood. 2007;109(1):93-9.Klein C, et al. Nat Genet. 2007;39(1):86-92.

First name:Karl

Last name:Welte


Address:OE 6780Hannover MedicalSchool


Further information:www.mh-hannover.de/Kliniken

Department and function:Professor, Dermatology

Education:Medical Doctor, Professor of Medicine

Positions:1985-1989 Post Doc in the Dept´s of Immunology in Hannover and in Goettingen1989-1994 Clinicail Education in the the Field of Dermatology in Hannoversince 1994: Registrar („Oberarzt“) in the Dept of Dermatology

Major research interests:Dermatoimmunology:Specifity and functions of skin infiltrating T-cells in eczemaRegulation of cytokine pattern in human T-cells and antigen-presentingcellsExpression and function of anaphylatoxin receptors

Selected Publications:Gutzmer R, Lisewski M, Zwirner J, Mommert S, Diesel C, Wittmann M, Kapp A, Werfel T. Immunology. 2004;111(4):435-43.Breuer K, Heratizadeh A, Wulf A, Baumann U, Constien A, Tetau D, Kapp A, Werfel T. Clin Exp Allergy. 2004; 34(5):817-24.Breuer K, Wulf A, Constien A, Tetau D, Kapp A, Werfel T. Allergy. 2004; 59(9):988-94.Wittmann M, Alter M, Stunkel T, Kapp A, Werfel T. Allergy Clin Immunol. 2004; 114(4):965-73.Gutzmer R, Diestel C, Mommert S, Kother B, Stark H, Wittmann M, Werfel T. J Immunol. 2005; 174(9):5224-32.Wittmann M, Purwar R, Hartmann C, Gutzmer R, Werfel T. J Invest Dermatol. 2005; 124(6):1225-33.Breuer K, Wittmann M, Kempe K, Kapp A, Mai U, Dittrich-Breiholz O, Kracht M, Mrabet-Dahbi S, Werfel T. Clin Exp Allergy. 2005; 35(8):1088-95.Werfel T, Breuer K, Rueff F, Przybilla B, Worm M, Grewe M, Ruzicka T, Brehler R, Wolf H, Schnitker J, Kapp A. Allergy. 2006;61(2):202-5.Wittmann M, Killig C, Bruder M, Gutzmer R, Werfel T. J Leukoc Biol. 2006; 80(1):75-86.Gutzmer R, Kother B, Zwirner J, Dijkstra D, Purwar R, Wittmann M, Werfel T. J Invest Dermatol. 2006;126(11):2422-9.Purwar R, Wittmann M, Zwirner J, Oppermann M, Kracht M, Dittrich-Breiholz O, Gutzmer R, Werfel T. J Immunol. 2006;177(7):4444-50.Turjanmaa K, Darsow U, Niggemann B, Rance F, Vanto T, Werfel T. Allergy. 2006; 61(12):1377-84.Langer K, Breuer K, Kapp A, Werfel T. Exp Dermatol. 2007 Feb;16(2):124-9.

First name:Werfel

Last name:Thomas

Acad. Title:Prof Dr. med.

Address:Dept DermatologyHannover Medical SchoolRicklinger Str. 530449 Hannover

Phone and e-mail:[email protected]@gmx.de

Further information:http://www.klinikum-hannover.de/hkl/

Department and function:Juniorprofessor, Dermatology

Education:1989 Abitur, Gymnasium am Geroweiher,

Mönchengladbach1989-96 University Studies, Human Medicine, Heinrich-Heine

University, Düsseldorf

Positions:1996 – 2003 Residency, Department of Dermatology, Hannover

Medical School1999-2001 Postdoctoral Research (DFG Grant)12/2002 - Juniorprofessor, Department of Dermatology,

Hannover Medical School

Major research interests:Inflammation in eczematous skin diseases, regulation of IL-12, Th1 / Th2 „specific“ transcription factors, heat shock proteins in inflammatory skin diseases (HSP70, HSP27, gp96)

Selected Publications:Wittmann et al. Blood 1999; 94:1717Wittmann et al. Int Arch Allergy Immunol 2001; 124:346Wittmann et al. J Immunol 2002; 168:3793Gutzmer R, Langer K, Mommert S, Wittmann M, Kapp A, Werfel T. J Immunol. 2003; 171(12):6363-71.Gutzmer R, Lisewski M, Zwirner J, Mommert S, Diesel C, Wittmann M, Kapp A, Werfel T. Immunology. 2004; 111(4):435-43Wittmann M, Alter M, Stunkel T, Kapp A, Werfel T. J Allergy Clin Immunol. 2004; 114(4):965-73Wittmann M, Purwar R, Hartmann C, Gutzmer R, Werfel T. J Invest Dermatol. 2005; 124(6):1225-33.Purwar R, Werfel T, Wittmann M. J Invest Dermatol. 2006;126(5):1043-51.Wittmann M, Killig C, Bruder M, Gutzmer R, Werfel T. J Leukoc Biol. 2006; 80(1):75-86Purwar R, Wittmann M, Zwirner J, Oppermann M, Kracht M, Dittrich-Breiholz O, Gutzmer R, Werfel T. J Immunol. 2006;177(7):4444-50.Purwar R, Werfel T, Wittmann M. J Invest Dermatol. 2007 Jan 18; [Epub ahead of print]

First name:Miriam

Last name:Wittmann


Address:Ricklinger Str. 530449 Hannover

Phone and e-mail:0511 9246 278miriamwittmann@ web.de

Further information:http://www.klinikum-hannover.de/hkl/

Department and function:Head, "In Vitro Differentiation" Group, IPK Gatersleben

Education:1964-1969 Study of biology at the Univ. of Greifswald1970-1974 PhD thesis at the Institute of Genetics Gatersleben /

University of Halle1997 Habilitation and venia legendi ("Cell Biology") at the

Medical Faculty, University of Halle

Positions:1974-1991 Scientific co-worker (Mutagenesis and embryonic

stem cell research) Institute of Genetics, Gatersleben, Academy of Sciences

Since 1992 Head of the Research Group "In Vitro Differentiation", IPK Gatersleben

Major research interests:-Stem cell research: Embryonic and adult (intestinal, hematopoietic) stem cells-Stem cell differentiation into cardiac, skeletal, vascular smooth muscle, neuronal and pancreatic cells-Analysis of cell-cell and cell-matrix interactions-Embryotoxicity analysis in vitro using embryonic stem cells

Selected Publications:Czyz J, Nikolova T, Schuderer J, Kuster N, Wobus AM. Mutat Res. 2004; 557(1):63-74.Rolletschek A, Blyszczuk P, Wobus AM.Toxicol Lett. 2004;149(1-3):361-9. Kania G, Blyszczuk P, Wobus AM. Int J Dev Biol. 2004; 48(10):1061-4.Kania G, Blyszczuk P, Jochheim A, Ott M, Wobus AM. Biol Chem. 2004; 385(10):943-53Blyszczuk P, Asbrand C, Rozzo A, Kania G, St-Onge L, Rupnik M, Wobus AM.. Int J Dev Biol. 2004;48(10):1095-104.Czyz J, Guan K, Zeng Q, Wobus AM. Int J Dev Biol. 2005;49(1):33-41.Kania G, Corbeil D, Fuchs J, Tarasov KV, Blyszczuk P, Huttner WB, Boheler KR, Wobus AM. Stem Cells. 2005;23(6):791-804.Nikolova T, Czyz J, Rolletschek A, Blyszczuk P, Fuchs J, Jovtchev G, Schuderer J, Kuster N, Wobus AM. FASEB J. 2005;19(12):1686-8.Wiese C, Rolletschek A, Kania G, Navarrete-Santos A, Anisimov SV, Steinfarz B, Tarasov KV, Brugh SA, et al. Stem Cells. 2006;24(9):2085-97.Wiese C, Kania G, Rolletschek A, Blyszczuk P, Wobus AM. Methods Mol Biol. 2006;325:181-205Blyszczuk P, Wobus AM. Methods Mol Biol. 2006;330:373-85.Rolletschek A, Kania G, Wobus AM. Diabetologia. 2006;49(11):2541-5.Schroeder IS, Kania G, Blyszczuk P, Wobus AM. Methods Enzymol. 2006;418:315-33.

First name:Anna M.

Last name:Wobus

Acad. Title:PD Dr. rer. nat.

Address:Institute of Plant Genetics (IPK Gatersleben)Corrensstr. 306466 Gatersleben


Further information:www.ipk-gatersleben.de

Documents

MD/PhD Program “Molecular Medicine“ - MH … Program “Molecular Medicine“ Hannover Biomedical Research School (HBRS) at Hannover Medical School Responsible Univ. Prof. Dr