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Lunch 11.45 – 13.00 13.00-13.25Siveke J. Molecular mechanism of tumor development in a mouse model of pancreatic cancer 13.25-13.50Bruns C Angiogenesis and metastasis regulating genes in pancreatic cancer 13.50-14.15Lechel A. - PowerPoint PPT Presentation
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Medizinische Hochschule HannoverCarl-Neuberg Straße 130625 HannoverTelefon: 0511-532 [email protected]
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Lunch 11.45 – 13.00
13.00-13.25 Siveke J.Molecular mechanism of tumor development in a mouse model of pancreatic cancer
13.25-13.50 Bruns CAngiogenesis and metastasis regulating genes in pancreatic cancer
13.50-14.15 Lechel A.Telomerase deletion limits progression of p53-mutant hepatocellular carcinoma with short telomeres in chronic liver disease
14.15-14.40 Müller-Schilling M.Molecular mechanisms of p53/p63 and p73 in hepatocarinogenesis
14.40-15.05 Malek N.P.Control of cell cycle progression and tissue homeostasis by p27 and cyclin E
Location:
Eibsee Hotel Am Eibsee 1-3D-82491 GrainauPhone: +49-(0)8821-98810
Distance:Grainau: 3 kmGarmisch-Partenkirchen: 11 km München: 97 kmInnsbruck: 68 kmFüssen: 59 km
Contact Information
Molecular pathogenesis and experimental therapy of gastrointestinal cancer –
07.March - 09. March 2007
Thursday 8th MarchCell biology and metabolismBreakfast 7.30 – 8.00
8.00-8.25 Straub B.A new form of cell contact: cis-E:N-Cadherin hybrids in normal and malignant liver cells
8.25-8.50 Skawran B.Chromatin remodeling and induction of chromosomal instability
8.50-9.15 Kern M.Prostaglandin metabolism in hepatocarcinogenesis
9.15-9.40 Nies A.Localisation and function of transmembrane transporters in HCC
9.40-10.05 Ryschich E.Time laps microscopy for investigation of tumor cell migration
Virology10.05-10.30 Urban S.
HepaRG-cells as a tool to study HBV-infection as well as hepatocyte-specific differentiation and polarization processes
10.30-11.00 Bartenschlager R.Strategies of hepatitis C virus replication and persistence
State of the art lecture: Molecular pathways of genomic instability
Division of Molecular Biology, The Netherlands Cancer Institute:
15.05-15.45 Jos JonkersMolecular pathways of genomic instability in cancer formation
Coffee break 15.45-16.15Immunology and Virotherapy 16.15-16.40 Zender L.
Impact of senescence on innate immunity in a HCC mouse model
16.40-17.05 Greten T.Role of Tregs and tumor cell death in
immunotherapy of HCC
17.05-17.30 Gütgemann I.A new model for antigen recognition in
hepatocellular carcinoma: LAPtTA x c- MYC/OVA transgenic mice 17.30-17.55 Becker P.
Strategies for immune-intervention
17.55-18.20 Ebert O.Treatment of hepatocellular carcinoma with tumor specific replicating visicular stomatitis virus
18.20-18.45 Kubicka S. Migration and expansion of dendritic cells as a tool for enhanced crosspresentation of tumorantigens by tumorspecific replicating viruses (Viro-
Immunotherapy)
19.30-20.00 Walk with torchlight 20.00 Rustic buffet in the Eibsee cottage
Friday 9th March
Breakfast 7.00-8.00
State of the art lecture: Academic drug developmentMedical School Hannover and HZI:
8.00-8.15 Malek N.P. Academic drug development for targeted therapy of cancer – part I
8.15-8.30 Kalesse M.Academic drug development for targeted therapy of cancer – part II
8.30-8.45 Frank R.Academic drug development for targeted therapy of cancer – part III
New experimental therapies:8.45-9.10 Mier W.
Endoradiotherapeutic procedures as a tool for tumor therapy
9.10-9.35 Ganten T.The promise of Trail – potential and risks of novel anti cancer therapy
9.35-10.00 de Toni E.Sensitising of cancer cells for receptor-mediated apoptosis: new therapeutic approach for HCC
Coffee break 10.00-10.30Molecular biology10.30-10.55 Breuhahn, K.
Dysregulation of FUSE-binding transcriptionfactors in hepatocarcinogenesis
10.55-11.20 Zender L. New mir30RNA libraries and comparative oncogenomics in GI oncology
11.20-11.45 Schneider G.Cell cycle regulation in Pancreatic cancer cells
11.00-11.25 Radlwimmer B.Array-CGH and gene methylation in HCC
11.25-11.50 Geffers R.Role of SNPs in carcinogenesis and cancer therapy
13.50-14.15 Gallmeier EDNA-repair gene alterations as a
pharmacogenomic target for the treatment of GI cancer
14.15-14.40 Kolligs F
Critical genes for development of colorectal cancer: new therapeutic targets?
14.40-15.05 Singer S.Mikrotubuli destabilising proteins as therapeutic targets for hepatocellular carcinoma
Genomics
Lunch 11.50 – 13.50
Potential therapeutic targets
