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Medical Physics Unit Annual Report 2015 1 McGILL UNIVERSITY - MEDICAL PHYSICS UNIT ANNUAL REPORT 2015 Jan Seuntjens, Ph.D., FCCPM, FAAPM, FCOMP Professor & Director Margery Knewstubb, Administrative Coordinator June, 2016 I. Activity Summary I.1. Background The main areas of interest in medical physics at present are: (i) treatment of cancer by ionizing radiation (radiation oncology physics); (ii) diagnostic imaging with x rays, ultrasound and nuclear magnetic resonance (diagnostic radiology physics); (iii) diagnostic imaging with radionuclides (nuclear medicine physics); and (iv) the study of radiation hazards and radiation protection (health physics). In recent years medical physics has grown into a complex multidisciplinary science with involvements and affinities to biomedical engineering, health and life sciences, systems biology and biophysics. Medical physics is also a rapidly expanding profession and job opportunities for graduates of medical physics programs, although affected by a saturating job market in the clinical profession, remain promising locally, nationally and internationally. McGill’s Medical Physics program has been in existence for 37 years and the program is playing a world-leading role in academic training of professionals as well as scientists in medical physics. The accreditation of graduate and residency programs in medical physics is generally provided by the Commission on Accreditation of Medical Physics Educational Programs (CAMPEP) sponsored by five organizations: the American Association of Physicists in Medicine (AAPM); the American College of Radiology (ACR); the American Society for Radiation Oncology (ASTRO); the Canadian Organization of Medical Physicists (COMP); and the Radiological Society of North America (RSNA). The MPU graduate programs in medical physics were first accredited in 1993 for a period of 5 years and reaccredited in 1998, in 2003, 2008 and 2013 for an additional 5-year period. McGill was the third university in North America with such accreditation and between 1993 and 2004 it was the only Canadian university with such an accreditation. Since 1997 the MPU also provides a residency program in radiation oncology physics. In this program graduates in medical physics receive a structured clinical-professional training in radiation oncology physics. The program received its first accreditation in 2000, and was re-accredited in 2005, 2010 and finally 2015 for an additional 5-year period to December 31, 2020. McGill is one of 10 institutions in Canada and one of 53 in North America with this type of

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McGILL UNIVERSITY - MEDICAL PHYSICS UNIT

ANNUAL REPORT 2015

Jan Seuntjens, Ph.D., FCCPM, FAAPM, FCOMP Professor & Director

Margery Knewstubb, Administrative Coordinator

June, 2016 I. Activity Summary

I.1. Background

The main areas of interest in medical physics at present are: (i) treatment of cancer by ionizing radiation (radiation oncology physics); (ii) diagnostic imaging with x rays, ultrasound and nuclear magnetic resonance (diagnostic radiology physics); (iii) diagnostic imaging with radionuclides (nuclear medicine physics); and (iv) the study of radiation hazards and radiation protection (health physics). In recent years medical physics has grown into a complex multidisciplinary science with involvements and affinities to biomedical engineering, health and life sciences, systems biology and biophysics. Medical physics is also a rapidly expanding profession and job opportunities for graduates of medical physics programs, although affected by a saturating job market in the clinical profession, remain promising locally, nationally and internationally. McGill’s Medical Physics program has been in existence for 37 years and the program is playing a world-leading role in academic training of professionals as well as scientists in medical physics. The accreditation of graduate and residency programs in medical physics is generally provided by the Commission on Accreditation of Medical Physics Educational Programs (CAMPEP) sponsored by five organizations: the American Association of Physicists in Medicine (AAPM); the American College of Radiology (ACR); the American Society for Radiation Oncology (ASTRO); the Canadian Organization of Medical Physicists (COMP); and the Radiological Society of North America (RSNA). The MPU graduate programs in medical physics were first accredited in 1993 for a period of 5 years and reaccredited in 1998, in 2003, 2008 and 2013 for an additional 5-year period. McGill was the third university in North America with such accreditation and between 1993 and 2004 it was the only Canadian university with such an accreditation. Since 1997 the MPU also provides a residency program in radiation oncology physics. In this program graduates in medical physics receive a structured clinical-professional training in radiation oncology physics. The program received its first accreditation in 2000, and was re-accredited in 2005, 2010 and finally 2015 for an additional 5-year period to December 31, 2020. McGill is one of 10 institutions in Canada and one of 53 in North America with this type of

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accreditation. Information about the MPU, its clinical, research and academic mission can be found under www.mcgill.ca/medphys. In 2013, the MPU program initiated the Medical Physics Research Training Network (MPRTN) together with the CAMPEP accredited medical physics program at Laval University. This structure provides resources for medical physics research training to a network consisting of McGill MPU, U Laval and collaborators from the National Research Council Canada, the Canadian Nuclear Safety Commission, the Massachusetts General Hospital Proton Centre, and industry. The networked training approach allows the MPU to provide trainees with an enriched training environment so that they are better prepared for employment roles in industry, government and academia, in addition to the well-established role in clinical professions. The MPRTN has improved access of trainees to expertise and opportunities available internationally. The MPRTN is currently funded by the Natural Sciences and Engineering Research Council through the CREATE program with contributions from McGill University, RI-MUHC as well as industry. More information about the MPRTN program can be found on http://mprtn.com. I.2. Highlights I.2.1. Research and Publications

The calendar year 2015 was a successful year in terms of output: 84 peer reviewed publications by MPU members; 58 published abstracts; 23 invited presentations; and 100 conference presentations. For complete listings, please consult Appendices IX-XII under: http://www.mcgill.ca/medphys/files/medphys/medical_physics_unit_annual_report_2015_final.pdf A history of MPU’s Research and Publications may be found at: http://www.mcgill.ca/medphys/academic/publications Similarly, the overall grant and project support revenue for year 2015 was substantial. For a listing of grants, projects and contracts, please consult Appendix XIII. I.2.2. Teaching and learning

Five M.Sc. students in medical physics graduated during 2015. All became Ph.D. students (three at McGill, one at U de Montreal, one at the University of Ottawa). Please consult Appendix II for the full list of graduated students. Demographic data is given in Appendix III. During the 2015 calendar year, 2 residents completed the two-year Residency Training Program in Radiation Oncology Physics (G. Aldosary, K. Zerouali). Since the initial McGill University residency program accreditation by CAMPEP in 2000, the number of Residency graduates amounts to 31 – the number of informal “on the job” ab initio training in radiation oncology physics at McGill prior to inception of the CAMPEP-accredited residency program is 16. The number of

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residents enrolled in the McGill program as of Fall 2015 stands at 15. This significant number of trainees is thanks to a Quebec-wide approach to the residency training. A listing of the residency graduates and various relevant data are provided in Appendix IV. The graduate teaching distribution during the 2015 calendar year is shown in the list of instructors for didactic courses in Appendix V. During the 2015 calendar year, all 12 mandatory graduate courses underwent evaluations by students. The results were circulated to staff, are filed in the MPU office, and their summaries without instructor identification are enclosed as Appendix VI. All individual instructors were evaluated separately and also 2 laboratory courses, having several instructors each, were evaluated based on the course itself as opposed to an individual instructor. On a scale of 1 (bad) to 5 (excellent) and averaged over all registered students, the evaluations for the Winter 2015 semester ranged from 2.84 to 4.97 and for the Fall 2015 semester they ranged from 4.42 to 4.99. A conclusion can be made that the MPU students are reasonably satisfied with the quality of education they receive, but that they also send a message to certain instructors that improvements in their teaching methods and attitudes could be made. Considering that the majority of individual instructors who taught didactic or laboratory courses during the 2015 calendar year come from the ranks of clinical physicists who partially volunteer their time and efforts to the academic activities of the MPU, the teaching evaluations attest to an excellent collaboration between the academic and clinical physicists of the MPU as well as to considerable commitment from the clinical staff to offer good quality teaching. Students who began either their first year, second year, or additional session of M.Sc. medical physics studies in Fall 2015 are listed in Appendix VII. The Ph.D. program, in collaboration with the Department of Physics and the Department of Biomedical Engineering (BME), grew dramatically over the past few years. The 18 students at various stages of their Ph.D. thesis work during Fall 2015 are listed in Appendix VIII. Most have either passed the preliminary examination at the Physics Department of McGill or their comprehensive project committee at the BME Department. The employment situation of M.Sc. medical physicists has become more restricted as a result of the 2014/2016 ABR/CCPM deadline (ABR: American Board of Radiology; CCPM: Canadian College of Physicists in Medicine). By this time every clinical medical physicist wishing to sit for the certification exams of the ABR or CCPM must come from a CAMPEP (CAMPEP: Commission for Accreditation of Medical Physics Education Programs) accredited residency program. Despite the increase in CAMPEP-accredited residency programs, access to these programs is severely restricted for M.Sc. graduates, since they often compete with Ph.D. candidates applying for the same positions. The recruitment philosophy of the MPU M.Sc. program, hence, is tending towards recruitment for candidates who are more likely interested in the Ph.D. program. In Winter 2015 the recruitment cohort of M.Sc. candidates consisted of 48 candidates, out of which the incoming cohort for September 2015 comprised 4

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new students. The incoming cohort for September 2016 is expected to consist of approximately similar likely slightly larger statistics. I.2.3. Accreditation review and cyclical review During the year 2013, the MPU was reviewed by the Commission for Accreditation of Medical Physics Education Programs (CAMPEP; http://www.campep.org). The accreditation review document was largely complementary although pointed to the fragility of the MPU structure. The report offered some suggestions but unconditional reaccreditation for 5-years (2013-2018) was received. Following CAMPEP suggestions, in terms of course offerings, the MPU is currently revising its M.Sc. curriculum with respect to the introduction of new courses in (1) Anatomy and Physiology, (2) Radiation Biology, and (3) Instrumentation. The unit also underwent Cyclical Review with site visit in November 2013. The report was again largely complimentary, but pointed to two key points and six other issues that must be addressed. The two key points in the report were:

1. “The structure of the unit makes it vulnerable to any of the core academic members leaving. As an example, the devastation by the recent departure of Dr. Bruce Pike was cited. Retention of the current director is seen by the review committee as a priority. Further, the review committee recommends (1) Five positions to be secured at the university to be staffed with a mix of junior and mid-career scientists. (2) Elevation from Unit status to Departmental status.”

2. “The imminent retirement of the core experimental Radiation Biologist (Dr. Lehnert) leaves a hole in the wet-lab capability of radiation biology expertise within (or accessible to) the unit.”

The faculty of medicine committed to increasing the staff to four TT positions. One of these positions (the 3rd) was posted during 2015 and a shortlist was achieved. The remaining (4th) TT position will be staffed in 2016. A potential transition to Departmental status remains a medium-term goal. With regards to point 2, the curriculum update committee has appointed Dr. Norma Ybarra to assume the role of course teacher for Radiation Biology (in lieu of Dr. Lehnert) and has done this for the past 2 years. Dr. Ybarra is a research associate in Seuntjens’ lab supported by CIHR funds. She is separately paid for her teaching contributions to the unit. An obviously more sustainable solution would be to appoint her using the budget freed by the retirement of Dr. Lehnert. One of the six other points raised by the review committee, was dry-lab space.

The need for dry lab space on the Glen has been pointed out to both Faculty and MUHC on different occasions. Currently, the MPU is housed in the Cancer Centre at the Glen. The dry lab space for this is inadequate and consists of borrowed clinical space. Unfortunately, there is no permanent solution to this. I.2.4. Involvement in the community

Members of the MPU are actively involved in clinical duties and also take up significant roles in professional and scientific committees and boards. Appendix XVI and Appendix XVII summarize the committee memberships within McGill and outside McGill, respectively. Of particular note are activities in committees of

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prestigious organizations such as the International Atomic Energy Agency (IAEA) and the International Commission for Radiation Units and measurements (ICRU). I.2.5. Partnerships Members of the MPU have a broad network of collaborators worldwide. Examples of these are international collaborations with hospitals and laboratories in Belgium, the UK, the US and others. In 2013, the MUHC cancelled the single and only physics residency position. Since then local residents have been supported by temporary replacements of clinical physicists in maternity leave, left-over budgets from research grants, etc. A very important partnership has improved the capacity of the medical physics residency program whereby the MPU is responsible for residency training of junior staff physicists in affiliate institutions. The MPU-MUHC has partnership agreements with (1) St. Peters (Albany); (2) U. Laval (CHUQ); (3) U. Montreal (CHUM); (4) Trois-Rivieres; (5) JGH and (6) Oman. During the year 2015, this model has developed further and the current number of clinical medical physics residents is 13 (see Appendix IV). I.2.6. Personnel and location changes during 2015

Unfortunately on May 1, 2015, a very productive faculty member Dr. I. El Naqa (TT) left McGill for University of Michigan. His leave left a significant hole in the unit’s profile in bio-informatics and image processing. Dr. El Naqa left behind all of his students as well as his operating grants. An active collaboration exists between Dr. El Naqa and the MPU and the students he supervised as well as the staff with whom he continues to collaborate. Similarly, Dr. Syme (CAS/Research, JGH) left the MPU in July 2015. Currently all clinical medical physicists at the MUHC and the JGH either have CAS-professional, CAS-research appointments in the department of Oncology or are affiliate member status in the MPU. Recent MPU members that have left McGill generally continue to hold adjunct faculty status and generally continue to participate in the co-supervision of graduate students. Adjunct professors in this capacity during 2015 are Dr. I. El Naqa and Dr. A. Syme. 2015 was also the year when the MPU moved to the Glen Cedars Cancer Centre. This move was taxing on the staff (clinical, research, and academic). Despite this, the academic programs have not significantly suffered from the disruption. The new facilities provide superior meeting and teaching spaces which is a positive factor for the functioning of the Unit. I.2.7. Honors, awards and prizes

The year 2015 was an extremely successful year with regards to scholarship awards to students. They can be summarized as follows:

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Table: External scholarships or awards granted to MPU students during the year

2015. Funding of the CREATE/MPRTN program is additional & not part of this listing. Student Name Scholarship

type/agency Supervisor

Eva Alonso-Ortiz

Magna Cum Laude –

ISMRM Merit Award

Levesque / Pike

Véronique Fortier FRQNT MSc Scholarship Levesque

Susannah Hickling

Lalageh Mirzakhanian

NSERC PhD Scholarship

Scholarship, Armenian General Benevolent

Union

El Naqa

Seuntjens

Logan Montgomery

Emmanuel Osunkwor

Scholarship, Canadian Partnership for Quality

Radiotherapy

CIBC Fellowship, Fac

Medicine, McGill U

Kildea

(supervisor to be conf.)

James Renaud Terry Fox Foundation, STARS21, U Toronto

J.R. Cunningham YIS

Second Prize, IOMP

Seuntjens

(idem)

Mikael Simard

Allison Toltz

Stella Xing

Judy Wang

FQRNT MSc Scholarship

RI-MUHC Internal

Scholarship

NSERC MSc Scholarship

Terry Fox Foundation,

STARS21, U Toronto

NSERC PhD Scholarship

NSERC PhD Scholarship

Levesque

(idem)

(idem)

Seuntjens

Levesque

Seuntjens

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Further awards or honors obtained/maintained during 2015 are:

Faculty awarded Type of award

Shirin Enger

Tony Falco

Horacio Patrocinio

G. Bruce Pike

Ervin Podgorsak

Andrew Reader

Jan Seuntjens

Moses & Sylvia Greenfield Award, Best paper –

Medical Physics, 2014 (awarded July 2015)

Lionel Boulet Prize, Govt. Québec (2015)

Fellow, Canadian Organization of Medical

Physicists (COMP)

Campus Alberta Innovates Program (CAIP) Chair in Healthy Brain Aging, U Calgary Distinction

& Research Award

Member of the Order of Canada

Killam Professor

James McGill Professor H. Grenville Smith Fellowship, RI-MUHC Fellow Canadian Organization of Medical Physicists (COMP)

Norma Ybarra Henry R. Shibata Fellowship

I.2.8. Fundraising The “Ervin B. Podgorsak Scholarship for Graduate Studies in Medical Physics” fund established in September 2013, only modestly increased during

2014 & 2015. The goal of the scholarship fund is to support outstanding Medical Physics students at the M.Sc. level in their studies. By creating this scholarship, the MPU is making a commitment to sustain Dr. Podgorsak’s dedication to academic excellence through increased student funding. Through the support of our faculty, alumni, and friends, the MPU fundraising committee hopes to create a scholarship fund by raising at least $10,000 per year for a minimum of four years. More information can be found on http://www.mcgill.ca/medphys/scholarship. The Facebook group “McGill Medical Physics Alumni and Friends” (https://www.facebook.com/groups/McGillMPU/) remained active in 2015.

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II Unit Status Update II.1 General objectives of the Medical Physics Unit

1) To promote the field of medical physics through teaching, research and

clinical service. 2) To encourage interest, education, training and research in medical

physics. 3) To join in one academic unit (Medical Physics Unit) the various members

of McGill departments, McGill University Health Centre and Jewish General Hospital who, through their academic training in physics, engineering or a related science and through work in clinical and academic environments, support the objectives (i) and (ii) above.

4) To offer a graduate program leading toward an M.Sc. degree in medical

physics. 5) To offer, in conjunction with McGill’s Physics and Biomedical Engineering

departments, a graduate program leading toward a Ph.D. degree in medical physics.

6) To offer a residency program in radiation oncology physics. 7) To maintain CAMPEP accreditation of the M.Sc. and Ph.D. academic

programs as well as the residency training program in radiation oncology physics.

8) To offer support to other institutions wishing to provide a residency

program in radiation oncology physics through affiliation with the CAMPEP-accredited McGill program.

9) To encourage, promote and excel in research in the application of physics

in diagnosis and treatment of human disease. 10) To promote McGill as an important institution in the international medical

physics community through excellence in teaching of, and research in, medical physics.

11) To promote national and international medical physics organizations

through active participation of the Medical Physics Unit and its members in these organizations.

12) To encourage links and collaboration between medical physicists,

clinicians and basic scientists with the goal of developing and improving methods for diagnosis and treatment of human disease.

13) To provide medical physics consultation services to McGill institutions,

national and international organizations and the general public, as required.

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14) To work with clinicians and basic scientists in the development of a strategic research program in radiation oncology.

15) To work with industry, government agencies, other CAMPEP accredited

programs as well as international academic institutions to update and modernize the graduate programs so that graduate students have access to expertise and equipment most suitable for their project and education.

II.2 Specific objectives for 2015-2016

The goals for the upcoming academic year will continue to address the 2013 cyclical review report, the curriculum revisions and the deployment of the MPRTN CREATE program as well as the need to further develop the Unit’s research capacity and support structure: 1) To continue rebuilding the academic program staffing and appoint more

CAS-research (with salary source MUHC and JGH) faculty.

2) To continue graduate program curriculum revisions commensurate recent developments in Medical Physics and its interaction with associated basic and clinical sciences. To continue establishing the CREATE courses and activities as outlined in the CREATE proposal.

3) In response to the cyclical review report (January 2014), to develop a

business plan for the future of the MPU, including consideration for Departmental status.

4) In response to the cyclical review report (January 2014), to address the

course teaching of Radiation Biology and recruitment of faculty in Radiation Biology.

5) To maintain the MPU’s operating budget to cover adequately the teaching

responsibilities of non-McGill clinical physics staff 6) To maintain and increase productivity with regard to standard academic

indicators (number of publications, presentations, graduating students, etc.).

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II.3. Overview Of McGill Medical Physics Program, staff and committee structure

Details regarding the graduate programs and research in medical physics can be found on the Medical Physics Unit website at: mcgill.ca/medphys.

Established: September 1979 by the Faculty of Medicine of McGill University Montréal

Directors: M. Cohen (September 1979 to August 1991)

E.B. Podgorsak (September 1991 to December 2008)

J. Seuntjens (January 2009 to present)

GRADUATE PROGRAMS:

• Graduate Program Director: Jan Seuntjens, Ph.D., FCCPM, FAAPM, FCOMP

• Degrees offered: M.Sc., Ph.D. and Certificate program in medical physics

• Accreditation: CAMPEP* accredited the M.Sc. & Ph.D. programs since 1993

• Re-accreditation: CAMPEP* re-accredited both programs (1998, 2003, 2008,

2013): • M.Sc. degrees conferred to date: 227

• Ph.D. degrees conferred to date: 34

• Current M.Sc. student enrollment: 12

• Current Ph.D. student enrollment: 19

• Number of mandatory courses: 12 (M.Sc), 2 (Ph.D), 2 (CREATE)

• Number of academic faculty: 7

• Number of clinical faculty: 19

• Number of adjunct members: 3

RESIDENCY PROGRAM IN RADIATION ONCOLOGY PHYSICS:

• Residency Program Director (RPD): William Parker, M.Sc., FCCPM

• Accreditation: CAMPEP* accredited the Residency program in 2000 • Re-accreditation: CAMPEP* re-accredited the program (2005, 2010) for 5 y

• Number of graduates to date: 47 (31 accredited & 16 non-accredited)

• Current enrollment: 12

• Program duration: 2 years

• Number of mandatory rotations: 4

• Number of mandatory courses: 4*

(*) If candidate does not come from CAMPEP accredited graduate program.

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The staff (see Appendix I) of the MPU consists of 37 staff members and a full-

time Administrative Coordinator (Margery Knewstubb). The MPU Administrative Coordinator holds the only permanent staff position in the MPU, and organizes the day-to-day activities of the MPU, deals with graduate students on a daily basis, corresponds with potential applicants to the medical physics program, and records minutes of MPU staff meetings. The MPU is led by a Director who is appointed by the Dean of Medicine. Since 1991 the directorship of the MPU is a part-time position, and is filled by the director of the Medical Physics Department of the McGill University Health Centre. Most members of the MPU hold primary appointments in the clinical departments of the JGH or the MUHC or in other major departments of McGill’s Faculty of Medicine (Biomedical Engineering, Neurology and Neurosurgery). For more information see Appendix I. The main responsibilities of clinical physicists are related to clinical aspects of radiation therapy and diagnostic radiology; however, the clinical physicists are involved with teaching of didactic medical physics courses and laboratories, as well as with co-supervision of graduate students. The engineers are involved with teaching of the course Medical Electronics. Four committees help with the running of the MPU: the Graduate Committee, Seminar Committee, the Curriculum Update Committee and the Alumni Committee. The Graduate Committee (Dr. J. Seuntjens, chair; Dr. S. Enger; M. Knewstubb; Dr. J. Kildea; Dr. I. Levesque; Dr. P. Francois (Dept Physics)) evaluates applications to the academic programs, decides on the number of candidates to be accepted for a particular academic year, and recommends the most suitable candidates for admission. For the 2015-2016 academic year, 48 complete applications were received by the MPU, and the graduate committee recommended to McGill 15 candidates for admission of which four registered to begin MSc Medical Physics studies in September 2015. For more information, please see Appendix VII.

The Seminar Committee (Dr. E. Soisson & Dr. J. Kildea for MUHC; Dr. S. Devic

for JGH) organizes the medical physics seminar series, a bi-monthly collection of seminars given by MPU staff, outside visitors or graduate students to staff and students of the MPU. The medical physics seminars organized during the Winter, Summer and Fall semesters of 2015 are listed in Appendix XV. The Curriculum Update Committee (Chair Dr. J. Seuntjens; Dr. S. Enger; Dr. J.

Kildea; Mr. W. Parker; Dr. M. Popovic; Dr. E. Soisson; Dr. N. Ybarra) reviews the curricula for the M.Sc. and Ph.D. programs. The Alumni Committee (chair Dr. E. Soisson, Dr. J Seuntjens, Dr. J Kildea, M.

Knewstubb, T. Nisic) aims to organize and improve the relations between the MPU and its alumni.

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III. Grants, publications, and service outside of McGill

III.1. Publications

The calendar year 2015 in relation to teaching, research, and service was a normal year for the MPU, with all performance indicators fairly stable in comparison to previous academic years. As demonstrated by the lists of publications (Appendix IX), published abstracts (Appendix X), invited presentations (Appendix XI), and presentations at national and international conferences (Appendix XII), all for calendar year 2015, the MPU staff are

productive, representing with distinction McGill's involvement in medical physics research. Historical academic productivity of MPU staff from 2003 to December 31, 2015 can be found at the following URLs: http://www.mcgill.ca/medphys/academic/publications

list of published papers list of published abstracts; list of invited presentations; list of presentations at national or international meetings.

III.2. Grants

The listing of research and teaching grants held by the MPU staff (Appendix XIII) also attests to the respectable professional standing of the MPU staff members. It should be noted that the grants are generally attained under the auspices of the grantee's primary department. Current research interests of the MPU academic staff members are shown in Appendix XIV. III.3. Committees and Boards

As shown in Appendices XVI and XVII, the MPU staff members are active on committees and boards within and outside of McGill. Currently, the MPU members serve on Boards of Directors of the two Canadian medical physics organizations: the Canadian College of Physicists in Medicine (CCPM) and the Canadian Organization of Medical Physicists (COMP). MPU staff members currently also serve on Boards of American Medical Physics organizations: the Commission on Accreditation of Medical Physics Education Programs (CAMPEP); the American Association of Physicists in Medicine (AAPM); and the AAPM Summer School, International Atomic Energy Agency (IAEA), and International Commission of Radiation Measurements and Units (ICRU) Task groups, Work Groups, committees and subcommittees. III.4. Other academic activities of the MPU

Three meetings of the MPU academic staff were held during the 2015 calendar

year. In January 2015, completion of the first and start of the second semester of the 2014-2015 academic year; in May 2015, completion of the second semester and start of M.Sc. thesis research work of the 2014-2015 academic year; and in September 2015, start of the 2015-2016 academic year. The purpose of the staff

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meetings is to discuss the issues affecting the MPU in general and the performance of graduate students in particular. Minutes of each staff meeting are taken by the graduate coordinator and distributed to staff and the Dean of Medicine as soon as possible following each meeting. The minutes of all staff meetings are filed in the MPU office and available for inspection upon request. During the Winter semester of the 2014-2015 academic year and the Fall semester of the 2015-2016 academic year, the MPU organized regular medical physics seminars on Fridays at noon given by staff, graduating students or

visiting scientists. The frequency of the seminars averaged three to four per month in the Fall semester and one per week in the Winter semester. Up to May 2015, the location was the Osler Amphitheatre at the Montreal General Hospital; from July to December 2015 the location was the RBC Conference Room at the McGill University Centre-Glen Site. The presentations are video linked to the SMBD-Jewish General Hospital and also to Centre de la Santé et des Services Sociaux-Laval (CSSSL) to allow MPU members there to attend without significantly disturbing their clinical activities. The attendance of seminars is mandatory for graduate students. A seminar committee headed by Dr. E. Soisson and Dr. J. Kildea organizes the seminars and a listing of the MPU medical physics seminars during the 2015 calendar year is given in Appendix XV. All McGill graduate students in medical physics are required to attend weekly formal research presentation meetings (Fridays at 9:15 a.m.). The

presentations are given either by staff or students. At least once every three – six months each student presents his or her research work and results, and thus gains practical experience on organizing and presenting scientific results. The speaker of a given seminar is introduced by the presenter of the previous seminar. Student attendance is compulsory and verified through a sign-up sheet. The senior Ph.D. student, who also serves as a student representative, organizes the weekly research seminars and organizes the sign-up sheet. All graduate students attend the weekly informal research meetings (Thursday

11:30 am) where students discuss daily problems and solutions in their research projects preceded by a review of journal papers. The weekly clinical physics meetings of the MUHC Medical Physics

Department are open to graduate students and some with particular interests in radiation oncology attend them regularly. Students are also encouraged to attend the weekly seminars (Monday morning rounds) organized by the Radiation

Oncology Department. Students are strongly encouraged to submit their work for presentation at national and international scientific meetings, either as regular presentations or as presentations during young investigator symposia. The awards won during 2015 are listed on Pages 5-6 of this Annual Report.

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IV. Discussion of performance

As evident from the Highlights (Section I.2) above and the Appendices to this report, the MPU staff and students have during the 2015 calendar year continued to bring some prestige to the University. They also fulfilled the basic objectives of the MPU. The MPU is known worldwide for its high quality teaching programs, and its M.Sc. and Ph.D. graduates generally do not have difficulties in finding suitable jobs upon graduation.

As shown in Appendices II through IV, graduates of McGill medical physics programs and the residency program are distributed in institutions throughout Québec, Canada, North America and around the world; quite a number of them in leadership positions. This attests to high standards of the McGill programs, helps with the retention of the CAMPEP accreditation, and attracts high quality graduate students and faculty into the programs. Despite the move to the Glen, one may state that 2015 was relatively stable for the MPU in relation to teaching, research, and service, with all performance indicators similar to those of previous academic years, providing the M.Sc. and Ph.D. students in Medical Physics with the academic standards they expect from McGill. A persistent problem of the Unit has been fragility with its very few core tenure track faculty members. During 2015 the MPU was able to post the position for replacement of Dr. El Naqa, and an additional TT position was committed by the Faculty of Medicine and will be filled in 2016. This will bring the TT faculty count to 4 for the first time since the mid-nineties. The close collaboration between clinical (JGH, MUHC) programs and academic faculty is essential to maintain this stability. In the past, this stability was engraved by ensuring that the academic director also holds the clinical chief position at the MUHC. Currently, the separation of the clinical departments from the academic core has the potential of creating silos leading to alienation between the members of the MPU. The reporting structure of MUHC and JGH clinical faculty through their managers to the respective mission or hospital administrations independent and aside from the academic leadership does not help in improving the stability of the MPU. The most recent cyclical review (2013) points out that the stability of the Unit in future years may require consideration of elevating the MPU to Departmental status.

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APPENDICES

I. List of MPU faculty members; List of MUHC Medical Physics staff; List of Residents (Fall 2015) ................................................................................... A-1 II. M.Sc. & Ph.D. degrees in medical physics during 2015 calendar year .................. A-6 III. Basic demographic data for M.Sc. and Ph.D. graduates ......................................... A-7 IV. List of Residency graduates 1999-2015 ............................................................... A-10 V. Course instructors: Winter 2015, Summer 2015, Fall 2015 ................................. A-12 VI. Course evaluations: Winter 2015 & Fall 2015 ..................................................... A-13 VII. Students in M.Sc. studies in Fall 2015 ................................................................. A-15 VIII. Students currently working on Ph.D. projects in medical physics ....................... A-17 IX. Publications by MPU staff during the 2015 calendar year ................................... A-19 X. Published abstracts by MPU staff during the 2015 calendar year ........................ A-24 XI. Invited presentations by MPU staff during the 2015 calendar year ..................... A-28 XII. Conference presentations by MPU staff during the 2015 calendar year .............. A-30 XIII. Research grants by MPU staff: January to December 2015 ................................. A-36 XIV. Current research interests of MPU staff ............................................................... A-44 XV. Medical physics seminars: January to December 2015 ........................................ A-47 XVI. Committee & board membership by MPU staff: 2015 (within McGill) .............. A-49 XVII. Committee & board membership by MPU staff: 2015 (outside McGill) ............. A-52

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APPENDIX I.

LIST OF FACULTY MEMBERS

MCGILL UNIVERSITY: MEDICAL PHYSICS UNIT FACULTY MEMBER DIVISION 1 JAN SEUNTJENS, PhD, FAAPM, FCCPM Clinical Director, Medical Physics Unit Professor, Department of Oncology 2 KRUM ASIEV, MSc, MCCPM Clinical Affiliate Member, Medical Physics Unit 3 D. LOUIS COLLINS, PhD Imaging Associate Member, Medical Physics Unit Associate Professor, Department of Neurology & Neurosurgery 4 TANNER CONNELL, PhD Clinical Affiliate Member, Medical Physics Unit 5 STEPHEN D. DAVIS, PhD, MCCPM, DABR Clinical Affiliate Member, Medical Physics Unit 6 FRANÇOIS DEBLOIS, PhD, FCCPM Clinical Associate Member, Medical Physics Unit Assistant Professor, Department of Oncology Clinical Chief, Medical Physics, JGH Dept Radiation Oncology 7 SLOBODAN DEVIC, PhD, FCCPM Clinical Affiliate Member, Medical Physics Unit Assistant Professor, Department of Oncology 8 ISSAM EL NAQA, PhD Clinical Associate Member, Medical Physics Unit Associate Professor, Department of Oncology 9 SHIRIN ENGER, PhD Clinical Associate Member, Medical Physics Unit Assistant Professor, Department of Oncology 10 MICHAEL D. C. EVANS, MSc, FCCPM, FCOMP Clinical Associate Member, Medical Physics Unit Assistant Professor, Department of Oncology 11 CHRISTOPHE FURSTOSS, PhD, MCCPM Clinical Affiliate Member, Medical Physics Unit

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MPU Faculty members (continued) FACULTY MEMBER DIVISION 12 ALAIN GAUVIN, MSc, MCCPM, DABMP, DABR Imaging Affiliate Member, Medical Physics Unit 13 GYORGY HEGYI, PhD Imaging Affiliate Member, Medical Physics Unit 14 MARITZA HOBSON, PhD Clinical Affiliate Member, Medical Physics Unit 15 JOHN KILDEA, PhD, MCCPM Clinical Associate Member, Medical Physics Unit Assistant Professor, Department of Oncology 16 PIERRE LÉGER, B.Eng Clinical Affiliate Member, Medical Physics Unit 17 SHIRLEY M. LEHNERT, PhD Clinical Associate Member, Medical Physics Unit Professor, Department of Oncology 18 IVES LEVESQUE, PhD Clinical Associate Member, Medical Physics Unit Assistant Professor, Department of Oncology 19 LI HENG LIANG, MSc, MCCPM Clinical Affiliate Member, Medical Physics Unit 20 BELAL MOFTAH, PhD, FCCPM Clinical Affiliate Member, Medical Physics Unit Adjunct Professor, Department of Oncology 21 WILLIAM A. PARKER, M.Sc., FCCPM Clinical Associate Member, Medical Physics Unit Assistant Professor, Department of Oncology Clinical Chief, Department of Medical Physics, MUHC Director, Residency Training Program 22 HORACIO J. PATROCINIO, M.Sc., FCCPM, FCOMP, DABR Clinical Associate Member, Medical Physics Unit Assistant Professor, Department of Oncology 23 G. BRUCE PIKE, Ph.D. Imaging Adjunct Professor, Medical Physics Unit Adjunct Professor, Department of Neurology & Neurosurgery 24 ERVIN B. PODGORSAK, PhD, FCCPM, FCOMP, FAAPM, DABR Clinical Emeritus Professor, Medical Physics Unit & Department of Oncology 25 EMILY POON, PhD, MCCPM Clinical Affiliate Member, Medical Physics Unit

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MPU Faculty members (continued) FACULTY MEMBER DIVISION 26 MARIJA POPOVIC, PhD, MCCPM Clinical Affiliate Member, Medical Physics Unit 27 ANDREW READER, PhD Imaging Associate Member, Medical Physics Unit Associate Professor, Department of Neurology & Neurosurgery 28 RICHARD B. RICHARDSON, PhD Clinical Affiliate Member, Medical Physics Unit Research Scientist, Internal Dosimetry Service 29 RUSSELL RUO, MSc, FCCPM, DABR Clinical Affiliate Member, Medical Physics Unit 30 ARMAN SARFEHNIA, PhD, MCCPM Clinical Affiliate Member, Medical Physics Unit Adjunct Professor, Department of Oncology 31 MONICA SERBAN, MSc, MCCPM Clinical Affiliate Member, Medical Physics Unit 32 EMILIE SOISSON, PhD, MCCPM, DABR, CMD Clinical Associate Member, Medical Physics Unit Assistant Professor, Department of Oncology 33 GABRIELA STROIAN, PhD, MCCPM Clinical Associate Member, Medical Physics Unit Assistant Professor, Department of Oncology 34 ALASDAIR SYME, PhD, FCCPM Clinical Affiliate Member, Medical Physics Unit Adjunct Professor, Department of Oncology 35 JONATHAN THÉBAUT, MSc Affiliate Member, Medical Physics Unit 36 NADA TOMIC, MSc, FCCPM Clinical Affiliate Member, Medical Physics Unit 37 NORMA YBARRA, PhD Affiliate Member, Medical Physics Unit Clinical _____________________________________________________________________________

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LIST OF STAFF MEMBERS

McGILL UNIVERSITY HEALTH CENTRE : DEPARTMENT OF MEDICAL PHYSICS

Director, Department of Medical Physics, MUHC Jan Seuntjens, PhD, FCCPM, FAAPM, FCOMP

Clinical Chief, Department of Medical Physics, MUHC

William Parker, M.Sc., FCCPM

Administrative officer/Research Coordinator Tatjana Nisic, MA Administrative Coordinator Margery Knewstubb

Medical Physicists Tanner Connell, PhD Stephen Davis, PhD, MCCPM, DABR Shirin Enger, PhD Michael Evans, MSc, FCCPM, Rad.Safety Officer, Class II, MUHC Gyorgy Hegyi, PhD Maritza Hobson, PhD, MCCPM, DABR John Kildea, PhD, MCCPM Ives Levesque, PhD Horacio Patrocinio, MSc, FCCPM, DABR Ervin B. Podgorsak, PhD, FCCPM, DABMP, FAAPM, FACMP (Professor

Emeritus) Emily Poon, PhD, MCCPM

Marija Popovic, PhD, FCCPM Russell Ruo, MSc, FCCPM Monica Serban, MSc, MCCPM Khushdeep Singh, MSc Emilie Soisson, PhD, CMD, MCCPM, DABR

Dosimetrists

Irene Marie Bélanger, RTT Jennifer Brown, RTT

Line Comeau, RTT), CMD Lioudmila Dychkant, RTT

Chris Kaufmann, RTT, CMD – Chief Dosimetrist Francesco Paolino, RTT, BS Maria Papageorgiou, RTT Cenzetta Procaccini, RTT

Electronic technicians Joe Larkin Bhavan Siva, BEng

Radiation Safety Officer (MUHC) Camille Pacher, M.Sc. Information systems technician

Suzana Darvasi, B.Sc.

Research Assistants Seema Ambareen, B.Sc Krishinima Jeyaseelan, B.Sc Research Associate Norma Ybarra, Ph.D.

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LIST OF RESIDENTS

MCGILL UNIVERSITY: MEDICAL PHYSICS UNIT

(Fall 2015)

McGill University Health Centre (Montreal General Hospital) ALAMRI, Ghada ALDOSARY, Ghada CONNELL, Tanner SINGH, Khushdeep McGill University Health Centre (SMBD-Jewish General Hospital) FAN, Michael GUILLET, Dominique Joint program: MUHC & St-Peter’s Hospital, Albany, NY ZAHARAKIS, Alex Centre Hospitalier de l’Université de Montréal AHANJ, Mohsen KAMIO, Yuji POULIN, Eric THAKUR, Varun ZEROUALI, Karim Centre Hospitalier de l’Université du Québec CANTIN, Audrey GOULET, Matthieu Centre de santé et des services sociaux, Trois-Rivières VINCENT, Sharlie

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6

APPENDIX II.

M.Sc. DEGREES IN MEDICAL PHYSICS : January-December 2015 1. QUINTERO MATEUS, Chrystian (N. Tomic, S. Devic)

Radiochromic film dosimetry system for clinical CTDI measurements Currently employed: PhD student, Université de Montréal

2. AHMED, Zaki (I. Levesque) Quantitative perfusion mapping using a novel reference region-based model for DCE-MRI Currently employed: Ph.D. student, McGill University, Montréal, Québec 3. CHRISTIANSEN, Eric (E. Vandervoort, J. Seuntjens) Calculation of correction factors for three detectors in small composite clinical fields for the

CyberKnife radiosurgery system Currently employed: Ph.D. student, Carleton University, Ottawa, Ontario 4. MIRZAKHANIAN, Lalageh (S. Enger) Investigation of the uncertainties involved int he low energy proton interactions in Geant Currently employed: Ph.D. student, McGill University, Montréal, Québec 5. XING, Stella (I. Levesque) Diffusion weighted magnetic resonance imaging in the characterization of soft tissue sarcoma Currently employed: Ph.D. student, McGill University, Montréal, Québec

Ph.D. DEGREES IN MEDICAL PHYSICS Project work completed in Fall 2015, thesis submitted and PhD oral defence in Winter 2016: 1. LEE, Sangkyu (I. El Naqa, J. Seuntjens) System radiobiology modeling of radiation induced lung disease Currently employed: Resident, Memorial Sloan Kettering, New York, New York 2. PAPACONSTADOPOULOS, Pavlos (J. Seuntjens) On the detector response and the reconstruction of the source intensity distribution in small photon fields Currently employed: Resident, SMBD-Jewish General Hospital, Montréal, Québec

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APPENDIX III.

BASIC DEMOGRAPHIC DATA

for the 227 M.Sc. and 34 Ph.D. GRADUATES

of the MEDICAL PHYSICS PROGRAMS

at McGILL UNIVERSITY (1980 – 2016)

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M.Sc. GRADUATES IN MEDICAL PHYSICS : 227

1980 – June 2016

MEDICAL PHYSICS UNIT : McGILL UNIVERSITY

Total number of M.Sc. graduates in medical physics: 227 Graduates’ origin: Quebec 76/227 another Canadian province 65/227 USA 13/227 another country 73/227 Working in medical physics: 193/227 in Quebec 79/193 in another Canadian province 54/193 in the USA 42/193 in another country 18/193 Currently Ph.D. student: 26/227 (21 in Quebec, 3 in other Canadian province, 1 in US, 1 in Europe) Origin of M.Sc. graduates currently working in Quebec: 80/227 Quebec 38/80 another Canadian province 12/80 USA 0/80 another country 30/80 M.Sc. graduates of Quebec origin: 76/227 working in medical physics 61/76 in Quebec 39/76 in another Canadian province 7/76 in the USA 12/76 in another country 3/76 Currently Ph.D. student: 8/76

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Ph.D. GRADUATES IN MEDICAL PHYSICS : 34

1983 – June 2016

MEDICAL PHYSICS UNIT : McGILL UNIVERSITY

Total number of Ph.D. graduates in medical physics: 34 Graduates’ origin: Quebec 9/34 another Canadian province 13/34 USA 0/34 another country 12/34 Working in medical physics: 33/34 in Quebec 11/33 in another Canadian province 10/33 in the USA 8/33 in another country 4/33 Origin of Ph.D. graduates currently working in Quebec: 11/34 Quebec 5/11 another Canadian province 3/11 USA 0/10 another country 3/11 Ph.D. graduates of Quebec origin: 9/34 working in medical physics 9/34 in Quebec 5/9 in another Canadian province 1/9 in the USA 3/9 in another country 0/9

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APPENDIX IV.

GRADUATES OF THE ACCREDITED TWO-YEAR RESIDENCY TRAINING PROGRAM

IN RADIATION ONCOLOGY PHYSICS AT MCGILL # Name

Date grad Background at entry Current position Current address

1 Belal Moftah, Ph.D. Dec ‘99 Ph.D. (high energy phys) U. British Columbia

Chief physicist Dept of Biomedical Physics, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia

2 Lara Dyke, Ph.D. May ‘00 M.Sc. (medical physics) U. Alberta

Clinical medical physicist

Varian Medical Systems, Miami, Florida, USA

3 Tony Falco, Ph.D. Dec ‘00 Ph.D. (medical physics) McGill U

Clinical medical physicist

Elekta (Resonant Medical), Incorporated Montreal, Quebec

4 Slobodan Devic, Ph.D. Mar ‘02 Post-graduate training Washington U

Clinical medical physicist

Dept Radiation Oncology, Jewish General Hospital, Montreal, Quebec

5 Kavita Murthy, M.Sc. May ‘02 M.Sc. (medical physics) McGill U

Clinical medical physicist

Canadian Nuclear Safety Commission Ottawa, Ontario

6 Jennifer Barker, M.Sc. Dec ‘02 M.Sc. (medical physics) McGill U

Clinical medical physicist

Dept Radiation Oncology, Jewish General Hospital, Montreal, Quebec

7 François DeBlois, Ph.D. Jul ‘03 Ph.D. (medical physics) McGill U.

Clinical medical physicist

Dept Radiation Oncology, Jewish General Hospital, Montreal, Quebec

8 Siobhan Ozard, Ph.D. Nov ‘03 Ph.D. (medical physics) U. British Columbia

Clinical medical physicist

Dept Medical Physics, Windsor Regional Cancer Centre, Windsor, Ontario

9 Wamied Abdel-Rahman, Ph.D.

Dec ‘05 Ph.D. (medical physics) McGill U.

Clinical medical physicist

Dept Radiation Oncology, King Faisal Specialist Hospital, Damman, Saudi Arabia

10 Yizhen Wang, M.Sc. May ’06 M.Sc. (medical physics) McGill U

Clinical medical physicist

Dept Radiation Oncology, Credit Valley Hospital, Mississauga, Ontario

11 Li Heng Liang, M.Sc.

Aug ‘06 M.Sc. (medical physics) McGill U

Clinical medical physicist

Dept Radiation Oncology, Jewish General Hospital, Montreal, Quebec

12 Nada Tomic, M.Sc. Aug ‘06 M.Sc. (medical physics) McGill U

Clinical medical physicist

Dept of Radiation Oncology, Jewish General Hospital, Montreal, Quebec

13 Gabriela Stroian, Ph.D.

Aug ‘07 Ph.D. (theoretical physics) U Paul Sabatier, France

Clinical medical physicist

Dept of Radiation Oncology, Jewish General Hospital, Montreal, Quebec

14 Eric Reynard, M.Sc.

Mar ‘09 M.Sc. (medical physics) McGill U

Clinical medical physicist

PEI Cancer Treatment Centre, Queen Elizabeth Hospital, Charlottetown, Prince Edward Island

15 Kristin Marchant, Ph.D.

Mar ‘09 Ph.D. (medical physics) McGill U

Clinical medical physicist

Dept Radiation Oncology, Allan Blair Cancer Centre, Regina, Saskatchewan

16

Krum Asiev, M.Sc. Jun ‘09 M.Sc. (medical physics) McGill U

Clinical medical physicist

Dept Radiation Oncology, Jewish General Hospital, Montreal, Quebec

17

Ismail Aldahlawi, M.Sc. Jun ‘10 M.Sc. (medical physics) McGill U

Clinical medical physicist

Dept Radiation Oncology, King Faisal Specialist Hospital, Damman, Saudi Arabia

18

Emily Poon, Ph.D. May ‘11 Ph.D. (medical physics) McGill U

Clinical medical physicist

Dept Medical Physics, McGill University Health Centre, Montreal, Quebec

19

Jonathan Thébaut, M.Sc. May ‘11 M.Sc. (medical physics) McGill U

Clinical medical physicist

Dept Radiation Oncology, Jewish General Hospital, Montreal, Quebec

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20

Arman Sarfehnia, Ph.D. Feb ‘12 Ph.D. (medical physics) U Western Ontario

Clinical medical physicist

Dept Medical Physics, McGill University Health Centre, Montreal, Quebec

21

John Kildea, Ph.D. Jun ‘12 Postdoc (astrophysics) Harvard U

Clinical medical physicist

Dept Medical Physics, McGill University Health Centre, Montreal, Quebec

22

Stephen Davis, Ph.D. Aug ‘12 Ph.D. (medical physics) U Wisconsin

Clinical medical physicist

Dept of Medical Physics, McGill University Health Centre, Montreal, Quebec

23

Joseph Holmes, M.Sc. Aug ‘12 M.Sc. (medical physics) McGill U

Clinical medical physicist

Kootenai Medical Centre, Coeur d’Alene, Idaho

24

Ellis Mitrou, M.Sc. Aug ‘13 M.Sc. (medical physics) McGill U

Clinical medical physicist

Dept Radiation Oncology, Jewish General Hospital, Montreal, Quebec

25

Marc Morcos, M.Sc. Aug ‘13 M.Sc. (medical physics) McGill U

Clinical medical physicist

Dept Radiation Oncology, Jewish General Hospital, Montreal, Quebec

26

Greg Twork, M.Sc. Aug ‘13 M.Sc. (medical physics) McGill U

Clinical medical physicist

Dept Medical Physics, McGill University Health Centre Montreal, Quebec

27

Amanda Dyess, M.Sc. Aug ‘14 M.Sc. (medical physics) McGill U

Clinical medical physicist

St Peter’s Hospital, Albany, New York

28 Hamed Bekerat, M.Sc. Aug ‘14 M.Sc. (medical physics) McGill U

Clinical medical physicist

Dept Radiation Oncology, Jewish General Hospital, Montreal, Quebec

29

Naomi Shin, M.Sc. Aug ‘14 M.Sc. (medical physics) McGill U

Clinical medical physicist

Dept Medical Physics, McGill University Health Centre, Montreal, Quebec

30 Ghada Aldosary, M.Sc. Oct ‘15 M.Sc. (medical physics) McGill U

Clinical medical physicist

British Columbia Cancer Agency, Vancouver, British Columbia (???)

31 Karim Zerouali, M.Sc. Nov’15 M.Sc. (medical physics) Univ de Montréal

Clinical medical physicist

Centre Hospitalier Université de Montréal, Montréal, Québec

Prior to 1999, there were x16 graduates of the non-CAMPEP-accredited Residency Training Program.

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12

APPENDIX V.

COURSE INSTRUCTORS : CALENDAR YEAR 2015

MEDICAL PHYSICS UNIT : McGILL UNIVERSITY

Course # Course Title Instructor(s) Winter semester 2015 MDPH 602 Applied Dosimetry S. Davis, J. Seuntjens MDPH 603 Laboratory in Radiation Physics S. Davis, M. Popovic (coord) MDPH 607 Physics of Medical Imaging * I. Levesque MDPH 609 Radiation Biology I. El Naqa, S. Lehnert, A. Syme, N. Ybarra MDPH 612 Computers in Medical Imaging H.J. Patrocinio, F. DeBlois MDPH 616D Selected Topics in Medical Physics E. Soisson, W. Parker (Part II) 563-625 D Thesis Research (individual supervisors) Summer semester 2015 MDPH 608 Lab in Diag. Radiol. & Nucl. Med. G. Hegyi, G. Stroian Fall semester 2015 MDPH 601 Radiation Physics * J. Seuntjens MDPH 611 Medical Electronics P. Léger MDPH 613 Health Physics J. Kildea, W. Parker MDPH 614 Physics of Diagnostic Radiology * S. Enger MDPH 615 Physics of Nuclear Medicine * S. Devic MDPH 616D Selected Topics in Medical Physics E. Soisson, W. Parker (Part I) * designates core courses

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Medical Physics Unit Appendix VI. Annual Report 2015

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APPENDIX VI.

McGill University - Medical Physics Unit Teaching Evaluation Summary - Winter 2015

Question

TO

TA

L

AV

G

A. Course material and presentation

1. Individual classes are well organized. 4.5 4.4 4.4 4.2 5.0 4.0 3.0 4.7 4.5 4.8 4.9 4.8 53.21 4.4

2. The instructor develops subject matter in a logical manner. 4.5 4.5 4.4 4.4 5.0 4.1 3.3 4.7 4.5 4.9 4.9 4.9 54.04 4.5 3. The instructor makes the material clear and interesting. 4.4 4.3 4.4 4.3 5.0 3.2 1.8 4.6 4.1 4.9 4.7 5 50.63 4.2

4. The instructor encourages and stimulates student thinking. 4.5 4.8 4.7 4.6 5.0 3.5 2.4 4.6 4.7 4.8 4.4 4.8 52.70 4.4 5. The instructor incorporates up-to-date information in the course. 3.7 4.7 4.4 4.4 5.0 4.3 3.0 4.6 4.6 4.9 4.3 4.8 52.64 4.4

6. The pace of the course is satisfactory. 4.2 4.7 4.2 4.1 5.0 2.9 3.1 4.7 4.3 4.8 4.7 4.9 51.61 4.3 7. The instructor speaks clearly. 4.5 4.6 4.5 4.5 5.0 3.9 3.6 4.8 4.1 4.8 5.0 5 54.28 4.5

8. The instructor makes good use of the blackboard or audiovisual aids. 4.7 4.7 4.3 4.2 5.0 3.8 3.1 4.7 4.6 4.9 4.8 4.9 53.62 4.5

B. Interaction with instructor

9. The instructor welcomes questions in class. 5.0 5.0 4.9 4.9 5.0 4.2 3.6 4.8 4.9 5.0 4.9 4.9 57.09 4.8

10. The instructor is available for consultation outside classes. 5.0 4.4 4.6 4.6 5.0 4.5 2.5 4.9 4.8 4.8 5.0 4.6 54.53 4.5 11. Consultation with the instructor is helpful. 5.0 4.9 4.5 4.5 5.0 4.7 3.0 5.0 4.8 4.9 5.0 4.9 56.10 4.7

C. Assignments and examinations

12. The mid-term exam questions are fair. 3.5 4.5 4.0 4.0 4.8 5.0 3.5 5.0 4.0

5.0 5.0 48.30 4.4

13. The mid-term exam marking and grading are fair. 2.0 4.5 4.0 4.0 4.8 5.0 4.0 5.0 4.0

5.0 5.0 47.30 4.3 14. Assignments contribute substantially to students' understanding of

course material. 4.0 4.5 4.5 4.6 4.9 5.0 2.9 4.4 2.5 4.8 4.9 5 51.96 4.3 15. Assignments returned sufficiently promptly for students to benefit

from corrections. 3.7 4.7 2.3 1.8 5.0 5.0 1.0 4.6 4.5 3.3 5.0 5 45.83 3.8

D. Overall assessment

16. You would like to take another course from the same instructor. 4.3 4.4 4.4 4.2 5.0 3.6 2.1 4.6 4.4 4.8 5.0 4.9 51.69 4.3

17. The instructor's overall teaching ability is excellent. 4.4 4.3 4.5 4.3 5.0 3.6 2.4 4.7 4.4 4.7 5.0 4.9 52.21 4.4 Overall average course rating for instructor. 4.23 4.58 4.28 4.20 4.97 4.14 2.84 4.73 4.33 4.72 4.85 4.9

Overall Average/5 4.39

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McGill University - Medical Physics Unit Teaching Evaluation Summary - Fall 2015

Question

A. Course material and presentation

1. Individual classes are well organized. 5.0 4.0 5.0 5.0 5.0 5.0 29.00 4.8 2. The instructor develops subject matter in a logical manner. 5.0 4.8 5.0 5.0 4.6 5.0 29.35 4.9

3. The instructor makes the material clear and interesting. 5.0 4.0 5.0 4.5 4.0 4.5 27.00 4.5 4. The instructor encourages and stimulates student thinking. 5.0 4.5 5.0 4.8 4.6 4.5 28.35 4.7

5. The instructor incorporates up-to-date information in the course. 5.0 4.8 5.0 5.0 5.0 5.0 29.75 5.0 6. The pace of the course is satisfactory. 5.0 4.5 5.0 4.5 3.0 5.0 27.00 4.5

7. The instructor speaks clearly. 5.0 4.5 5.0 5.0 4.6 5.0 29.10 4.9 8. The instructor makes good use of the blackboard or audiovisual aids. 5.0 4.8 5.0 5.0 4.8 4.8 29.30 4.9

B. Interaction with instructor

9. The instructor welcomes questions in class. 5.0 4.5 5.0 5.0 5.0 5.0 29.50 4.9 10. The instructor is available for consultation outside classes. 5.0 5.0 5.0 4.8 4.4 4.8 28.90 4.8

11. Consultation with the instructor is helpful. 5.0 4.8 5.0 5.0 4.5 4.8 29.00 4.8

C. Assignments and examinations

12. The mid-term exam questions are fair. 5.0 4.5 5.0 5.0 4.4 5.0 28.90 4.8

13. The mid-term exam marking and grading are fair. 4.8 4.8 5.0 4.8 3.4 5.0 27.65 4.6 14. Assignments contribute substantially to students' understanding of course material. 4.8 3.8 4.8 4.7 4.8 4.7 27.38 4.6

15. Assignments returned sufficiently promptly for students to benefit from corrections. 5.0 4.3 5.0 5.0 4.8 5.0 29.05 4.8

D. Overall assessment

16. You would like to take another course from the same instructor. 5.0 4.3 5.0 5.0 4.0 5.0 28.25 4.7

17. The instructor's overall teaching ability is excellent. 5.0 4.0 5.0 5.0 4.2 4.8 27.95 4.7

Overall average course rating for instructor. 4.97 4.44 4.99 4.88 4.42 4.86

Overall Average/5 4.76

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APPENDIX VII.

STUDENTS BEGINNING THEIR FIRST YEAR OF

M.Sc. STUDIES IN MEDICAL PHYSICS IN SEPTEMBER 2015

(major department and supervisor are indicated in parentheses; number following the major department indicates year of M.Sc. study in Fall 2015)

1. ALMAKDESSI, Georges (MPU-1, to be confirmed)

(title of thesis not yet available)

2. MODCHALINGAM, Mithunan (MPU-1, to be confirmed)

(title of thesis not yet available)

3. OSUNKWOR, Emmanuel (MPU-1, to be confirmed)

(title of thesis not yet available)

4. SHARIFPOUR, Shiva (MPU-1, to be confirmed)

(title of thesis not yet available)

These students started their studies in September 2015, selected their supervisor(s) in Winter 2016, and are expected to begin their M.Sc. thesis research work in Summer 2016.

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STUDENTS BEGINNING THEIR SECOND YEAR OF

M.Sc. STUDIES IN MEDICAL PHYSICS IN SEPTEMBER 2015

(major departments and supervisors are indicated in parentheses; number following the major department indicates year of M.Sc. study in Fall 2015)

1. DIAMANT-BOUSTEAD, André (MPU-2, I. Levesque)

Modelling lung SBRT treatment outcomes using Bayesian network averaging

(submitted final thesis – Winter 2016; graduated June 2016)

2. DOBRI, Simon (MPU-2, S. Enger)

(title of thesis not yet available)

3. FAMULARI, Gabriel (MPU-2, S. Enger)

(title of thesis not yet available)

4. FORTIER, Véronique (MPU-2, I. Levesque)

(title of thesis not yet available)

5. JOSEPH, Ackeem (MPU-2, J. Kildea)

(title of thesis not yet available)

6. MONTGOMERY, Logan (MPU-2, J. Kildea)

(title of thesis not yet available)

7. O’ GRADY, Kyle (MPU-2, J. Seuntjens)

Monte Carlo modeling of the Varian TrueBeam linear accelerator, with chamber effects

included in determination of the source parameters

(finished project work in Fall 2015; submitted initial thesis in Winter 2016)

8. SCHNEIDER, James (MPU-2, S. Devic)

(title of thesis not yet available)

9. SIMARD, Mikaël (MPU-2, I. Levesque)

(title of thesis not yet available)

10. VALLIÈRES, Simon (MPU-2, J. Seuntjens)

(title of thesis not yet available)

These students began their M.Sc. studies in September 2014, completed the Fall and Winter didactic semesters of the 2014-2015 academic year, and are currently completing their M.Sc. thesis research. All are expected to submit their theses by Fall 2016.

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APPENDIX VIII. STUDENTS CURRENTLY WORKING ON Ph.D. PROJECTS

IN MEDICAL PHYSICS IN SEPTEMBER 2015 (major department and supervisors are indicated in parentheses)

1. AHMED, Zaki (Physics – I. Levesque) (title not yet available) Expected to submit thesis: date not yet available (began Ph.D. studies in September 2015) 2. ALONSO ORTIZ, Eva (Physics – I. Levesque, G.B. Pike) (title not yet available) Expected to submit thesis: December 2016 (began Ph.D. studies in September 2011) 3. CARRIER-VALLIÈRES, Martin (Physics – I. El Naqa) (title not yet available) Expected to submit thesis: date not yet available (began Ph.D. studies in September 2012) 4. HICKLING, Susannah (Physics – J. Seuntjens) (title not yet available) Expected to submit thesis: date not yet available (began Ph.D. studies in September 2014) 5. JAPIASSU, Fernando (Physics – J. Seuntjens) (title not yet available) Expected to submit thesis: date not yet available (began Ph.D. studies in September 2014) 6. MARKEL, Daniel (Physics – I. El Naqa) (title not yet available) Expected to submit thesis: date not yet available (began Ph.D. studies in September 2011) 7. MIRZAKHANIAN, Lalageh (Physics – J. Seuntjens) (title not yet available) Expected to submit thesis: date not yet available (began Ph.D. studies in September 2015) 8. MULLINS, Joel (Physics – J. Seuntjens) (title not yet available) Expected to submit thesis: date not yet available (began Ph.D. studies in January 2014) 9. NOVOSAD, Philip (Physics – L. Collins) (title not yet available) Expected to submit thesis: date not yet available (began Ph.D. studies in September 2014) 10. PATER, Piotr (Physics – I. El Naqa, J. Seuntjens) (title not yet available) Expected to submit thesis: date not yet available (began Ph.D. studies in September 2011)

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11. PEREZ, Jessica (Biomedical Engineering – I. El Naqa, J Nadeau) (title not yet available) Expected to submit thesis: date not yet available (began Ph.D. studies in January 2012) 12. RENAUD, James (Physics –J. Seuntjens) (title not yet available) Expected to submit thesis: date not yet available (began Ph.D. studies in September 2012) 13. RENAUD, Marc-André (Physics –J. Seuntjens, F. DeBlois) (title not yet available) Expected to submit thesis: date not yet available (began Ph.D. studies in September 2012) 14. TOLTZ, Allison (Physics – J. Seuntjens) (title not yet available) Expected to submit thesis: date not yet available (began Ph.D. studies in September 2012) 15. WATSON, Peter (Physics – J. Seuntjens) (title not yet available) Expected to submit thesis: date not yet available (began Ph.D. studies in January 2013) 16. ZLATEVA, Yana (Physics – I. El Naqa) (title not yet available) Expected to submit thesis: date not yet available (began Ph.D. studies in September 2013) PhD project work completed Fall 2015 / oral defence Winter 2016: LEE, Sangkyu (Physics – I. El Naqa, J. Seuntjens) System radiobiology modeling of radiation induced lung disease Expected to submit thesis & oral defence: Winter 2016 (began Ph.D. studies in September 2010) PhD oral defence February 2016 / Graduating May 2016: PAPACONSTADOPOULOS, Pavlos (Physics – J. Seuntjens) On the detector response and the reconstruction of the source intensity distribution in small photon fields Graduating: June 2016 (began Ph.D. studies in September 2011)

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APPENDIX IX.

PUBLICATIONS

by members of the Medical Physics Unit : 2015 calendar year (x 84) (names of MPU staff members are underlined, students are indicated by †)

1. M. Boccardi, M. Bocchetta, F.C. Morency, D.L. Collins, M. Nishikawa, R. Ganzola, M.J. Grothe, D. Wolf,

A. Redolfi, M. Pievani, L. Antelmi, A. Fellgiebel, H. Matsuda, S. Teipel, S. Duchesne, C.R. Jack, G.B. Frisoni, Training labels for hippocampal segmentation based on the EADC-ADNI harmonized hippocampal protocol, Alzheimer’s & Dementia 11(2), 175-183 (2015).

2. L. French, C. Gray, G. Leonard, M. Perron, G.B. Pike et al, Early cannabis use, polygenic risk score for schizophrenia and brain maturation in adolescence, J. Amer. Med. Assoc.-Psychiatry 72(10), 1002-11 (2015).

3. M.A. Hobson, S.D. Davis, Comparison between an in-house 1D profile correction method and a 2D correction provided in Varian’s PDPC package for improving the accuracy of portal dosimetry images, J. Appl. Clin. Med. Phys. 16, 43–50 (2015).

4. P. Watson†, E. Mainegra-Hing, N. Tomic, J. Seuntjens, Implementation of an efficient Monte Carlo calculation for CBCT scatter correction: phantom study, J. Appl. Clin. Med. Phys. 16(4), 216-227 (2015).

5. A. Toltz†, N. Shin†, E. Mitrou†, C. Laude, C.R. Freeman, J. Seuntjens, W. Parker, D. Roberge, Late radiation toxicity in Hodgkin lymphoma patients: Proton therapy's potential, J. Appl. Clin. Med. Phys. 16(5), 5386 (2015).

6. O.M. Maria†, A.M. Maria, N. Ybarra, K. Jeyaseelan, S. Lee†, J. Perez†, M.Y. Shalaby, S. Lehnert, S. Faria, M. Serban, J. Seuntjens, I. El Naqa, Mesenchymal stem cells adopt lung cell phenotype in normal and radiation-induced lung injury conditions, Appl. Immunohist. Mol. Morphol. (July 2015, e-pub ahead of print).

7. S. Asgharizadeh†, H. Bekerat, A. Syme, S. Aldelaijan, F. DeBlois, T. Vuong, M. Evans, J. Seuntjens, S. Devic, Radiochromic film-based quality assurance for CT-based high-dose-rate brachytherapy, Brachy. 14(4), 578-85 (2015).

8. K. Marečková, M.M. Chakravarty, C. Lawrence, G. Leonard, D. Perusse, M. Perron, G.B. Pike, L. Richer, S. Veillette, Z. Pausova, T. Paus, Identifying craniofacial features associated with prenatal exposure to androgens and testing their relationship with brain development, Brain Struct. Funct. 220(6), 3233-44 (2015).

9. K. Weier, B. Banwell, A. Cerasa, D.L. Collins, A. Dogonowski, H. Lassmann, A. Quattrone, M.A. Sahraian, H.R. Siebner, T. Sprenger, The role of the cerebellum in multiple sclerosis, Cerebellum 14(3), 364-74 (2015).

10. Y. Xiao, V.S. Fonov, S. Beriault, F. Al Soubaie, M.M. Chakravarty, A.F. Sadikot, G.B. Pike, D.L. Collins, Multi-contrast unbiased MRI atlas of a Parkinson's disease population, Int. J. Comput. Assist. Radiol. Surg. 10(3), 329-41 (2015).

11. H. Rivaz, D.L. Collins, Deformable registration of pre-operative MR, pre-resection ultrasound and post- resection ultrasound: Comparing three approaches, Int. J. Comp. Assist. Radiol. Surg. 10(7), 1017-28 (2015).

12. Y. Xiao, V.S. Fonov, S. Beriault, I. Gerard, A.F. Sadikot, G.B. Pike, D.L. Collins, Patch-based label fusion segmentation of brainstem structures with dual-contrast MRI for Parkinson's disease, Int. J. Comput. Assist. Radiol. Surg. 10(7), 1029-41 (2015).

13. I. Gerard, D.L. Collins, An analysis of tracking eror in image guided neurosurgery, Int. J. Compu. Assist. Radiol. Surg. 10(10), 1579-88 (2015).

14. R. Zelmann,, S. Beriault, M.M. Marinho, K. Mok, J.A. Hall, N. Guizard, C. Haegelen, A. Olivier, G.B. Pike, D.L. Collins, Improving recorded volume in mesial temporal lobe by optimizing stereotactic intracranial electrode implantation planning, Int. J. Comput. Assist. Radiol. Surg. 10(10), 1599-615 (2015).

15. M. Kersten-Oertel, I. Gerard, S. Drouin, K. Mok, D. Sirhan, D. Sinclair, D.L. Collins, Augmented reality in neurovascular surgery: Feasibility and first uses in the operating room, Int. J. Comput. Assist. Radiol. Surg. 10(11), 1823-36 (2015).

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16. T. Vuong, S. Devic, High-dose-rate pre-operative endorectal brachytherapy for patients with rectal cancer, J. Contemp. Brachyth. 7(2), 183-8 (2015). doi: 10.5114/jcb.2015.51402. Epub 2015 May 6. Review.

17. A. Rabinovich, L. Bernard, A.V. Ramanakumar, G. Stroian, W.H. Gotlieb, S. Lau, B. Bahoric, Para-aortic and pelvic extended-field radiotherapy for advanced-stage uterine cancer: Dosimetric and toxicity comparison between the four-field box and intensity-modulated techniques, Curr. Oncol. 22(6), 405-411 (2015).

18. N. Stikov, J.S. Campbell, T. Stroh, M. Lavelée, S. Frey, J. Novek, S. Nuara, M.K. Ho, B.J. Bedell, R.F. Dougherty, I.R. Leppert, M. Boudreau, S. Narayanan, T. Duval, J. Cohen-Ada, P.A. Picard, A. Gasecka, D. Côté, G.B. Pike, Quantitative analysis of the myelin g-ratio from electron microscopy images of the macaque corpus callosum, Data Brief 17(4), 368-73 (2015).

19. T. Paus, Z. Pausova, M. Abrahamowicz, D. Gaudet, G. Leonard, G.B. Pike, L. Richer, Saguenay youth study: A multi-generational approach to studying virtual trajectories of the brain and cardio-metabolic health, Dev. Cogn. Neurosci. 11, 129-44 (2015).

20. J.R. Pruett, Jr., S. Kandala, S. Hoertel, A.Z. Snyder, J.T. Elison, T. Nishino, E. Feczko, N.U.F. Dosenbach, B. Nardos, J.D. Power, B. Adeyemo, K.N. Botteron, R.C. McKinstry, A.C. Evans, H.C. Hazlett, S.R. Dager, S. Paterson, R.T. Schultz, D.L. Collins, V.S. Fonov, M. Styner, G. Gerig, S. Da, P. Kostopoulos, J.N. Constantino, A.M. Estes, The IBIS Network, S.E. Petersen, B.L. Schlaggar, J. Piven, Accurate age classification of 6 and 12 month-old infants based on resting-state functional connectivity magnetic resonance imaging data, Dev. Cogn. Neurosci. 12C, 123-133 (2015).

21. Y. Zeighami, M. Ulla, Y. Iturria-Medina, M. Dadar, Y. Zhang, K.M. Larcher, V. Fonov, A.C. Evans, D.L. Collins, A. Dagher, Network structure of brain atrophy in de novo Parkinson’s disease, Elife 4, e08440 (2015).

22. B. Nitzsche, S. Frey, D.L. Collins, J. Seeger, D. Lobsien, A. Dreyer, H. Kirsten, M.H. Stoffel, V.S. Fonov, J. Boltze, A stereotaxic, population-averaged T1w ovine brain atlas including cerebral morphology and tissue volumes, Front. Neuro. 9, 69 (2015).

23. M.M. Chakravarty, J. Rapoport, J. Giedd, A. Raznahan, P. Shaw, D.L. Collins, J. Lerch, N. Gogtay, Striatal shape abnormalities as novel neurodevelopmental endophenotypes in schizophrenia: A longitudinal study, Hum. Br. Mapp. 36(4), 1458-69 (2015).

24. P. Coupé, V.S. Fonov, C. Bernard, A. Zandifar, S.F. Eskildsen, C. Helmer, J.V. Manjón, H. Amieva, J.F. Dartigues, M. Allard, G. Catheline, D.L. Collins, Detection of Alzheimer’s disease signature in MR images seven years before conversion to dementia: Toward an early individual prognosis, Hum. Br. Mapp. 36(12), 4758-70 (2015).

25. C.A. Beers, R.J. Williams, I. Gaxiola-Valdez, D.J. Pittman, A.T. Kang, Y. Aghakhani, G.B. Pike, B.G. Goodyear, P. Federico, Patient specific hemodynamic response functions associated with interictal discharges recorded via simultaneous intracranial EEG-fMRI, Hum. Br. Mapp. 36(12), 5252-64 (2015).

26. E. Alonso-Ortiz†, I.R Levesque, G.B. Pike, MRI-based myelin water imaging: A technical review, Magn. Reson. Med. 73(1), 70–81 (2015).

27. N. Stikov, M. Boudreau, I.R. Levesque, C.L. Tardif, J.K. Barral, G.B. Pike, On the accuracy of T1 mapping: Searching for common ground, Magn. Reson. Med. 73(2), 514–522 (2015).

28. T. Zhang, J.M. Pauly, I.R. Levesque, Accelerating parameter mapping with a locally low rank constraint, Magn. Reson. Med. 73(2), 655–661 (2015).

29. Y. Ma, A.J. Berman, G.B. Pike, The effect of dissolved oxygen on the relaxation rates of blood plasma: Implications for hyperoxia calibrated BOLD, Magn. Reson. Med. 74(6), (2015). DOI: 10.1002/mrm.26069.

30. G. Aldosary†, A. Nobah, F. Al-Zorkani, S. Devic, B. Moftah, A practical method of modelling a treatment couch using cone-beam computed tomography for intensity-modulated radiation therapy and RapidArc treatment delivery, Med. Dosim. 40(4), 304-313 (2015). pii: S0958-3947(15)00033-3. doi: 10.1016/j.meddos.2015.03.008.

31. M.A. Renaud†, D. Roberge, J. Seuntjens, (2015) Latent uncertainties of the pre-calculated track Monte Carlo method, Med. Phys. 42, 479 (2015).

32. S. Lee†, N. Ybarra, K. Jeyaseelan, S. Faria, N. Kopek, P. Brisebois, J.D. Bradley, C. Robinson, J. Seuntjens, I. El Naqa, Bayesian network ensemble as a multivariate strategy to predict radiation pneumonitis risk, Med. Phys. 42(5), 2421-2430 (2015). doi: 10.1118/1.4915284.

33. J.R. Hiatt, S.D. Davis, M.J. Rivard, A revised dosimetric charcterization of the model S700 electronic brachytherapy source containing an anode-centering plastic insert and other components not included in the 2006 model, Med. Phys. 42, 2764–2776 (2015).

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34. J. Seuntjens, L. Beaulieu, D.L. Collins, P. Despres, S. Devic, I. El Naqa, J. Nadeau, G.B. Pike, A. Reader, MO-DE-BRA-04: The CREATE Medical Physics Research Training Network: Training of new generation innovators, Med Phys. 42(6), 3557 (2015).

35. D. Lewis, S. Devic, Correcting scan-to-scan response variability for a radiochromic film-based reference dosimetry system, Med. Phys. 42, 5692 (2015). doi: 10.1118/1.4929563.

36. H. Bouchard, Y. Kamio†, H. Palmans, J. Seuntjens, S. Duane, Detector dose response in megavoltage small photon beams: II-Pencil beam perturbation effects, Med. Phys. 42(10), 6048-6061 (2015).

37. H. Bouchard, J. Seuntjens, S. Duane, Y. Kamio†, H. Palmans, Detector dose response in megavoltage small photon beams: I-Theoretical concepts, Med. Phys. 42(10), 6033-6047 (2015).

38. R. Maglieri†, A. Licea, M. Evans, J. Seuntjens, J. Kildea, Measuring neutron spectra in radiotherapy using the nested neutron spectrometer, Med. Phys. 42, 6162- 6169 (2015).

39. J. Renaud†, A. Sarfehnia, K. Marchant, M.R. McEwen, C. Ross, J. Seuntjens, Direct measurement of electron beam quality conversion factors using water calorimetry, Med. Phys. 42(11), 6357-6368 (2015).

40. D. Roberge, C. Leclerc-Champagne, R. Doucet, J. Seuntjens, How low should you go: Choice of minimum dose prescription in cranial radiosurgery, Cureus, J. Med. Sci. 7(6), e282 (2015).

41. K. Weier, C. Till, V. Fonov, E.A. Yeh, D.L. Arnold, B. Banwell, D.L. Collins, Contribution of the cerebellum to cognitive performance in children and adolescents with multiple sclerosis, J. Mult. Scler. July 22, 2015: Epub ahead of print.

42. N. Akbar, B. Aubert-Broche, B.L. Banwell, C. Till, D.L. Collins, Altered resting-state functional connectivity in cognitively preserved pediatric-onset MS patients and relationship to structural damage and cognitive performance, J. Mult. Scler. Journal, September 11, 2015: Epub ahead of print.

43. K. Weier, V. Fonov, B. Aubert-Broche, D.L. Arnold, B. Banwell, D.L. Collins, Impaired growth of the cerebellum in pediatric-onset acquired CNS demyelinating disease, J. Mult. Scler. November 9, 2015: Epub ahead of print.

44. W. Poon, X. Zhang, D. Bekah†, J.G. Teodoro, J.L. Nadeau, Targeting B16 tumors in vivo with peptide-conjugated gold nanoparticles, Nanotech. 26(8), 285101 (2015). Epub June 26, 2015.

45. D.P. Hibar et al, G.B. Pike et al, P.M. Thompson, S.E. Medland, Common genetic variants influence human subcortical brain structures, Nature 520(7546), 224-9 (2015).

46. S.F. Eskildsen, P. Coupé, V.S. Fonov, J.C. Pruessner, D.L. Collins, Alzheimer's disease neuroimaging initiative, Structural imaging biomarkers of Alzheimer's disease: Predicting disease progression, Neurobiol. Aging 36, S23-31 (2015).

47. B.S. Khundrakpam, J. Tohka, A.C. Evans, Brain Development Cooperative Group (D.L. Collins et al.), Prediction of brain maturity based on cortical thickness at different spatial resolutions, Neuroimage 111, 350-9 (2015).

48. N. Guizard, P. Coupé, V.S. Fonov, J.V. Manjón, D.L. Arnold, D.L. Collins, Rotation-invariant multi-contrast non-local means for MS lesion segmentation (RMNMS), NeuroImage: Clinical 8, 376-89 (2015).

49. K. Nakamura, R.A. Brown, S. Narayanan, D.L. Collins, D.L. Arnold, Diurnal fluctuations in brain volume: Statistical analyses of MRI from large populations, Neuroimag. 118, 126-132 (2015).

50. N. Stikov, J.S. Campbell, T. Stroh, M. Lavelée, S. Frey, J. Novek, S. Nuara, M.K. Ho, B.J. Bedell, R.F. Dougherty, I.R. Leppert, M. Boudreau, S. Narayanan, T. Duval, J. Cohen-Adad, P.A. Picard, A. Gasecka, D. Côté, G.B. Pike, In vivo histology of the myelin g-ratio with magnetic resonance imaging, Neuroimage 118, 397-405 (2015).

51. D.M. Cash, C. Frost, L.O. Iheme, D. Ünay, M. Kandemir, J. Fripp, O. Salvado, P. Bourgeat, M. Reuter, B. Fischl, M. Lorenzi, G.B. Frisoni, X. Pennec, R. Pierson, J.L. Gunter, M.L. Senjem, C.R. Jack Jr, N. Guizard, V.S. Fonov, D.L. Collins et al, Assessing atrophy measurement techniques in dementia: Results from the MIRIAD atrophy challenge, Part 1: Methodology, repeatability and symmetry, NeuroImage 123, 149-164 (2015).

52. D.M. Cash, C. Frost, L. O. Iheme, D. Ünay, M. Kandemir, J. Fripp, O. Salvado, P. Bourgeat, M. Reuter, B. Fischl, M. Lorenzi, G.B. Frisoni, X. Pennec, R. Pierson, J.L. Gunter, M.L. Senjem, C.R. Jack Jr, N. Guizard, V.S. Fonov, D.L. Collins et al, Assessing atrophy measurement techniques in dementia: Results from the MIRIAD atrophy Challenge, Part 2: Comparison of required sample sizes for clinical trials, NeuroImage 123, 149-164 (2015).

53. S.A. Grover, B. Aubert-Broche, D. Fetco, D.L. Collins, D.L. Arnold, M. Finlayson, B.L. Banwell, R.W. Motl, E.A. Yeh, Lower physical activity is associated with higher disease burden in pediatric multiple sclerosis, Neurology 85(19), 1663-9 (2015).

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54. N. Faridi, S. Karama, M. Burgaleta, M.T. White, A.C. Evans, V.S. Fonov, D.L. Collins, D.P. Waber, Neuroanatomical correlates of behavioral rating versus performance measures of working memory in typically developing children and adolescents, Neuropsych. 29(1), 82-91 (2015).

55. J. Ansado, D.L. Collins, V.S. Fonov et al., A new template to study callosal growth shows specific growth in anterior and posterior regions of the corpus callosum in early childhood, Eur. J. Neurosci. 42, 1675-1684 (2015).

56. I.J. Gerard, J.A. Hall, K. Mok, D.L. Collins, New protocol for skin landmark registration in image-guided neurosurgery: Technical note, Neurosurg. 11(3), 376- 81 (2015).

57. M. Hatt, M. Majdoub, M. Vallières†, F. Tixier, C.C. Le Rest, D. Groheux, E. Hindié, A. Martineau, O. Pradier, R. Hustinx, R. Perdrisot, R. Guillevin, I. El Naqa, D. Visvikis, 18F-FDG PET uptake characterization through texture analysis: investigating the complementary nature of heterogeneity and functional tumor volume in a multi-cancer site patient cohort, J. Nucl. Med. 56(1), 38-44 (2015). doi: 10.2967/jnumed.114.144055. Epub 2014 Dec 11.

58. A. Bezdjian, M.A. Mujica-Mota, S. Devic, S.J. Daniel, The effect of radiotherapy on gentamicin ototoxicity: An animal model, Otolaryn. Head Neck Surg. 152(6), 1094-1101 (2015).

59. L. Beaulieu, I. El Naqa, P. Després, J. Seuntjens, Special section: Selected papers from the Fifth International Workshop on Monte Carlo Techniques in Medical Physics, Phys. Med. Biol. 60(13), 4947-4950 (2015).

60. M. Vallières†, C.R. Freeman, S.R. Skamene, I. El Naqa, A radiomics model from joint FDG-PET and MRI texture features for the prediction of lung metastases in soft-tissue sarcomas of the extremities, Phys. Med. Biol. 60, 471 (2015). Editors’s Choice.

61. M. Serban, J. Seuntjens, E. Roussin, A. Alexander, J-R. Tremblay, W. Wierzbicki, Patient-specific compensation for Co-60 TBI treatments based on Monte Carlo design: A feasibility study, Physica Medica 32: pp. 67-75, (2015).

62. S. Aldelaijan, F. Alzorkany, B. Moftah, I. Buzurovic, J. Seuntjens, N. Tomic, S. Devic, Use of a control film piece in radiochromic film dosimetry, Physica Medica: Eur. J. Med. Phys. 32(1), 202-207 (2015). doi: 10.1016/j.ejmp.2015.12.004.

63. M. Bernal, M.C. Bordage, J. Brown, M. Davidkova, M. Delage, Z. El Bitar, S.A. Enger, Z. Francis, S. Guatelli, V. Ivantchenko, M. Karamitros, I. Kyriakou, L. Maigne, S. Meylan, K. Murakami, S. Okada, H. Payno, Y. Perrot, T. Pham, H. Tran, T. Sasaki, V. Stepan, C. Villagrasa, S. Incerti, Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit, Physica Medica: Eur. J. Med. Phys. 31, 861–874 (2015).

64. N. Guizard, V.S. Fonov, D. Garcia-Lorenzo, K. Nakamura, B. Aubert-Broche, D.L. Collins, Spatio-temporal regularization for longitudinal registration to subject-specific 3D template, PLoS ONE 10(8), e0133352 (2015).

65. M. Lecavalier-Barosum, L. Souhami, F. Cury, M. Duclos, R. Ruo, S. Faria, Pelvic lymph node displacement in high-risk prostate cancer patients treated with image guided intensity modulated radiation therapy with 2 independent target volumes, Pract. Radiat. Oncol. 5(6), 406-10 (2015).

66. S. Shrivastava, J.J. Mansure, W. Almajed, F. Cury, G. Ferbeyre, M. Popovic, J. Seuntjens, W. Kassouf, The role of HMGB1 in radio-resistance of bladder cancer, Mol. Can. Therap., e-pub December 2015.

67. T. Vuong, R.A. Nout, T.M. Niazi, A. Garant, A. Bujold, A.G. Martin, S. Ferland, G. Stroian, J. Thebaut, A. Syme, S. Devic, Radiation therapy as a curative modality for patients with rectal cancer, Int. J. Radiat. Oncol. Biol. Phys. 93(3), e168-e169 (2015). DOI:10.1016/j.ijrobp.2015.07.982.

68. G.M. Videtic, C. Hu, A.K. Singh, J.Y. Chang, W. Parker, K.R. Olivier, S.E. Schild, R. Komaki, J.J. Urbanic, H. Choy, A randomized phase 2 study comparing 2 stereotactic body radiation therapy schedules for medically inoperable patients with stage I peripheral non-small cell lung cancer, NRG Oncology RTOG 0915 (NCCTG N0927), Int. J. Radiat. Oncol. Biol. Phys. 93(4), 757-64 (2015). doi: 10.1016/j.ijrobp.2015.07.2260. Epub 2015 Jul 17.

69. C.M. Poole, A. Ahnesjö, S.A. Enger, Determination of subcellular compartment sizes for estimating dose variations in radiotherapy, Radiat. Prot. Dosim. 166(1-4), 361-364 (2015).

70. A. Nobah, M. Mohiuddin, S. Devic, B. Moftah, Effective spatially fractionated GRID radiation treatment planning for a passive grid block, Br. J. Radiol. 88, 20140363 (2015); doi: 10.1259/bjr.20140363.

71. J. Coates†, A.K. Jeyaseelan, N. Ybarra, M. David, S. Faria, L. Souhami, F. Cury, M. Duclos, I. El Naqa, Contrasting analytical and data-driven frameworks for radiogenomic modeling of normal tissue toxicities in prostate cancer, Radiother. Oncol. 115(1), 107-13 (2015). pii: S0167-8140(15)00142-5. doi: 10.1016/j.radonc.2015.03.005.

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72. D. Fang, S. Hu, Y. Liu, V-H Quan, J. Seuntjens, S.D. Tran, Identification of the active components in bone marrow soup: A mitigator against irradiation-injury to salivary glands, Sci. Rep. 5, 16017 (2015).

73. R. Harmouche, N.K. Subbanna, D.L. Collins, D.L. Arnold, T. Arbel, Probabilistic multiple sclerosis lesion classification based on modelling regional intensity variability and local neighbourhood information, IEEE Trans. Biomed. Eng. 62(5), 1281-92 (2015).

74. H. Rivaz, S.J.S Chen, D.L. Collins, Automatic deformable MR-ultrasound registration for image-guided neurosurgery, IEEE Trans. Med. Imag. 34(2), 366-80 (2015).

75. Z. Karimaghaloo, H. Rivas, D.L. Collins, D.L. Arnold, T. Arbel, Temporal hierarchical adaptive texture CRF for automatic detection of Gadolinium-enhancing multiple sclerosis lesions in brain MRI, IEEE Trans. Med. Imag. 34(6), 1227-41 (2015).

76. B.H. Menze, A. Jakab, S. Bauer, J. Kalpathy-Cramer, K. Farahani, J. Kirby, Y. Burren, N. Porz, J. Slotboom, R. Wiest, L. Lanczi, E. Gerstner, M. Weber, T. Arbel, B. B. Avants, N. Ayache, P. Buendia, D. L. Collins, et al, The multimodal brain tumor image segmentation benchmark (BRATS), IEEE Trans. Med. Imag. 34(10), 1993-2024 (2015).

77. S. Beriault, Y. Xiao, D.L. Collins, G.B. Pike, Automatic SWI venography segmentation using conditional random fields, IEEE Trans. Med. Imag. 34(12), 2478-2491 (2015).

78. H. Rivaz, D.L. Collins, Near real-time robust non-rigid registration of volumetric ultrasound images for neurosurgery, Ultra. Med. Biol. 41(2), 574-587 (2015).

79. D. Stoyanov, D.L. Collins, I. Sakuma, P. Abolmaesumi, P. Jannin, Information processing in computer-assisted interventions: 5th international conference, 2014 in “International Journal of Computer Assisted Radiology and Surgery”, pp. 1355- 1356, Springer International Publishing.

80. B. Aubert-Broche, V. Fonov, K. Weier, S. Narayanan, D.L. Arnold, B. Banwell, D.L. Collins, Is it possible to differentiate the impact of pediatric monophasic demyelinating disorders and multiple sclerosis after a first episode of demyelination?, in “Spatio-temporal Image Analysis for Longitudinal and Time-Series Image Data: Lecture Notes in Computer Science”, pp. 38-45, Springer International Publishing.

81. S. Drouin, M. Kersten-Oertel, D.L. Collins, Interaction-based registration corection for improved augmented reality overlay in neurosurgery, Augmented environments for computer assisted interventions’ (Proceedings of MICCAI AE-CAI Workshop 2015), Lecture Notes in Computer Science, Volume 9365, 21–29 (2015).

82. M. Kersten-Oertel, I.J. Gerard, S. Drouin, K. Mok, D. Sirhan, D.S. Sinclair, D.L. Collins, Augmented reality for specific neurovascular surgical tasks: Augmented environments for computer assisted interventions (Proceedings of MICCAI AE-CAI Workshop 2015), Lecture Notes in Computer Science, Volume 9365:92-103 (2015).

83. S. Lee†, I. El Naqa, Machine learning methodology, in I. El Naqa, R. Li, M.J. Murphy, “Machine Learning in Radiation Oncology”, pp. 21-39 (2015), Springer International Publishing.

84. K. Kudinov, D. Cooper†, P. Tyagi, D. Bekah†, D. Bhattacharyya, C. Hill, H.J. Kin, J.L. Nadeau, S.G. Bradforth, Evidence of energy transfer in nanoparticle-porphyrins conjugates for radiation therapy enhancement, Proc. SPIE 9338 Colloidal Nanoparticles for Biomedical Applications X 93380H (March 12, 2015); doi:10.1117/12.2077985.

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APPENDIX X.

PUBLISHED ABSTRACTS

by members of the Medical Physics Unit : 2015 calendar year (x 58) (names of MPU staff members are underlined, students are indicated by †)

1. M. Vallieres†, A. Diamant-Boustead†, S. Laberge, I.R. Levesque, I. El Naqa, A machine learning approach

for creating texture-preserved MRI tumor, Med. Phys. 42(6), 3323; 57th Annual Meeting & Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA, SU-J-E-250.

2. L. Liang, H. Bekerat†, N Tomic, F. DeBlois, S. Devic, M. Morcos†, M. Popovic, P. Watson†, J. Seuntjens, Impact of the radiochromic film energy response on dose measurements of low energy electronic brachytherapy sources, Med. Phys. 42(6), 3440 (2015).

3. P. Pater†, G. Bäckström†, M.F. Villegas, A. Ahnesjö, S. Enger, J. Seuntjens, I. El Naqa, Influence of proton track-cell nucleus incidence angle on relative biological effectiveness, Med. Phys. 42(6), 3448; 57th Annual Meeting & Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA (poster), SU-E-T-494.

4. M.A. Renaud†, R. Flynn, J. Seuntjens, S.A. Enger, Rotating shield high dose rate brachytherapy with 153Gd and 75Se isotopes, Med. Phys. 42, 3455 (2015).

5. L. Mirzakhanian†, V. Giusti, S.A. Enger, Investigation of the uncertainties involved in secondary neutron/gamma production in Geant4/MCNP6 Monte Carlo codes for proton therapy application, Med. Phys. 42, 3455 (2015).

6. P. Pater†, G. Bäckström†, M.F. Villegas, A. Ahnesjö, S.A. Enger, J. Seuntjens, I. El Naqa, On the value of LET as a radiation quality descriptor in RBE-LET relationships, Med. Phys. 42(6), 3469; 57th Annual Meeting & Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA (poster), SU-E-T-581.

7. S. Aldelaijan, F. Alzorkany, B. Moftah, F. Alrumayan J. Seuntjens, D. Lewis, S. Devic, Radiochromic film quenching effect reduction for proton beam dosimetry, Med Phys. 42(6), 3489 (2015). doi: 10.1118/1.4925028.

8. D. Markel†, I.R. Levesque, J. Larkin, P. Leger, I. El Naqa, Temporally realistic manipulation a 4D biomechanical lung phantom for evaluation of simultaneous registration and segmentation, Med. Phys. 42(6), 3549; 57th Annual Meeting & Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA, MO-AB-BRA-09.

9. J. Seuntjens, L. Beaulieu, L. Collins, P. Despres, S. Devic, I. El Naqa, J. Nadeau, G.B. Pike, A. Reader, The CREATE medical physics research training network: Training of new generation innovators, Med. Phys. 42(6), 3557; 57th Annual Meeting & Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA (oral presentation), MO-DE-BRA-04.

10. Y. Zlateva†, I. El Naqa, Cherenkov emission dosimetry: Feasibility for electron radiotherapy, Med. Phys. 42(6), 3567; 57th Annual Meeting and Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA, BEST IN PHYSICS (THERAPY), presentation, MO-FG-303-2.

11. I. El Naqa, Radiomics and the coming pan-omics revolution, Med. Phys. 42(6), 3632; 57th Annual Meeting & Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA, TU-G-303-04.

12. J. Renaud†, A. Sarfehnia, J. Seuntjens, Development of a probe-format graphite calorimeter for practical clinical dosimetry: Numerical design optimization, prototyping, and experimental proof-of-concept, Med. Phys. 42(6), 3649; 57th Annual Meeting & Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA (accepted), WE-AB-BRB-01.

13. I. El Naqa, Cranial TCP/NTCP modeling insights and caveats, Med. Phys. 42(6), 3685; 57th Annual Meeting & Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA, WE-F-304-05.

14. J. Seuntjens IAEA/AAPM code of practice for the dosimetry of static small photon fields, Med. Phys. 42(6), 3700; 57th Annual Meeting & Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA (oral presentation), TH-A-213-02.

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15. I. Das, J. Seuntjens, Small field dosimetry: Overview of AAPM TG-155 and the IAEA-AAPM code of practice,

Med. Phys. 42(6), 3700; 57th Annual Meeting & Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA (oral presentation), TH-A-213-0.

16. F. Liu, A. Tai, P. Lee, T. Biswas, G. Ding, I. El Naqa, J. Grimm, A. Jackson, F. Kong, T. LaCouture, B. Loo, M. Miften, T. Solberg, X. Li, Tumor control probability modeling for stereotactic body radiation therapy of early-stage lung cancer using multiple bio-physical models, Med. Phys. 42(6), 3701; 57th Annual Meeting & Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA, TH-AB-304-04.

17. S. Hickling†, P. Leger, I. El Naqa, Amplitude and frequency characteristics of acoustic waves induced following radiotherapy linear accelerator irradiation, Med. Phys. 42(6), 3723; 57th Annual Meeting & Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA, TH-CD-304-06.

18. Z. Ahmed†, I. El Naqa, I.R. Levesque, A constrained linear reference region model for DCE-MRI, Med. Phys. 42(6), 3735; 57th Annual Meeting & Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA, TH-CD-207-03.

19. J. Seuntjens, Standards for non-standard photon beams, Med. Phys. 42(6), 3739; 57th Annual Meeting & Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA (oral presentation), TH-E-304-04.

20. M. McEwen, R. Tosh, A Sarfehnia, J. Seuntjens, Reference dosimetry for beam modalities other than MV photons, Med. Phys. 42(6), 3739; 57th Annual Meeting & Exhibition of the American Association of Physicists in Medicine, July 12-16, Anaheim, CA (oral presentation), TH-E-304-0.

21. M. Carrier-Vallieres†, C.R. Freeman, Z. Ahmed†, R Turcotte, M. Hickeson, M. Serban et al, Early assessment of tumor aggresiveness using joint FDG-PET/MRI textural features: Prediction of prospective cohortand potential improvement using hypoxya and perfusion biomarkers, Int J. Rad. Oncol. Biol. Phys 93 (3) S6 (2015).

22. P. Papaconstadopoulos†, L. Archambault, J. Seuntjens, On the accuaracy of the Exradin W1 and the spectrum calibration method in scintillation dosimetry for small fields, J. Eur. Soc. Radioth. Oncol. 115(1), S71, abs. OC-0149 (Proffered papers); 3rd Forum - ESTRO, Radiotherapy & Oncology, Barcelona, Spain, April 24-28, 2015.

23. P. Pater†, G. Bäckström†, M.F. Villegas, A. Ahnesjö, S.A. Enger, J. Seuntjens, Initial DNA damage patterns with MC track structure and ionization clusters, Radioth. Oncol. 115(1), S76-S77; 3rd Forum - ESTRO, Radiotherapy & Oncology, Barcelona, Spain, April 24-28, 2015.

24. T. Vuong, T. Niazi, S. Devic, Role of endoluminal brachytherapy for rectal cancer: Current status and challenges, Radioth. Oncol. 115(1), S111 (2015).

25. B. Moftah, A. Basfar, K. Rabaeh, A. Almousa, M.A. Al Kafi, S. Devic, Radiation response of an improved optical CT based 3D gel dosimeter for radiation therapy quality assurance, Radioth. Oncol. 115(1), S183 (2015).

26. S. Aldelaijan, S. Devic, M. Shehadeh, F. Alzorkany, K. Al-Hadyan, G. Alsbeih, J. Seuntjens, B. Moftah, Dose calibration and monitoring for radiobiological experiments with low energy proton beams, Radioth. Oncol. 115(1), S217; 3rd Forum - ESTRO, Barcelona, Spain, April 24-28, 2015.

27. S. Devic, H. Mohammed, S. Aldelaijan, N. Tomic, J. Seuntjens, F. DeBlois, S. Lehnert, S.L. Faria, FDG based glycolytic biological target volume: Warburg effect vs. hypoxia, Radiother. Oncol. 115(1), S385; 3rd Forum - ESTRO, Barcelona, Spain, April 24-28, 2015.

28. L. Liang, H. Bekerat†, N. Tomic, F. DeBlois, T. Vuong, S. Devic, A. Nobah, M. Mohiuddin, B. Moftah, Optimal beam quality for linac-based spatially fractionated grid radiation therapy (SFGRT), Radiother. Oncol. 115(1), S385; 3rd Forum - ESTRO, Barcelona, Spain, April 24-28, 2015.

29. P. Watson†, M. Popovic, J. Seuntjens, An in-air Monte Carlo investigation of a miniature low energy x-ray tubes, J. Eur. Soc. Radioth. Oncol. 115(1), S412; abs. PO-0820, (poster presentation) - 3rd Forum - ESTRO, Barcelona, Spain, April 24-28, 2015.

30. M. Renaud†, J. Seuntjens, Mixed beam inverse planning strategies, J. Eur. Soc. Radiother. Oncol. 115(1), S457; abs. PO-0890 (poster discussion): 3rd Forum - ESTRO, Barcelona, Spain, April 24-28, 2015.

31. J. Coates†, A.K. Jeyaseelan, N. Ybarra, J. Tao†, M. David, S. Faria, L. Souhami, F. Cury, M. Duclos, I. EL Naqa, Evaluation of NTCP radiogenomic modeling frameworks in hypofractionated prostate cancer patients, J. Eur. Soc. Radiother. Oncol. 115(1), S464-465; abs. PO-0901 (poster presentation); 3rd Forum - ESTRO, Radiotherapy & Oncology, Barcelona, Spain, April 24-28, 2015.

32. J. Seuntjens, L. Beaulieu, D.L. Collins, S. Devic, I. El Naqa, J.L. Nadeau, G.B. Pike, A. Reader, The CREATE Medical Physics Research Training Network: Training of new generation innovators in medical physics, Radiother. Oncol. 115(1), S544; 3rd Forum - ESTRO, Barcelona, Spain, April 24-28, 2015.

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33. N. Tomic, C. Quintero†, F. DeBlois, J. Seuntjens, S. Devic, Radiochromic film based dose measurements

during radiotherapy 4D CT-simulation, Radiother. Oncol. 115(1), S755; 3rd Forum - ESTRO, Barcelona, Spain, April 24-28, 2015,

34. M. Serban, M.A. Renaud†, R. Maglieri†, A. Alexander, C.R. Freeman, Eliminating dosimetric uncertainties in tomotherapy delivery in sarcoma patients planned using Monte Carlo techniques, Radioth. Oncol. 115, S786-S787; 3rd Forum - ESTRO, Barcelona, Spain, April 24-28, 2015.

35. F. Villegas, G. Bäckström†, S.A. Enger, A. Ahnesjö, Impact of the microdosimetric spread on LQ-parameterization of cell survival data for protons and Co-60 photons, Radiother. Oncol. 115(1), S803; 3rd Forum - ESTRO, Barcelona, Spain, April 24-28, 2015,

36. K.S. Hyung, V. Fonov, D.L. Collins, G. Gerig, IBIS Network, M.A. Styner, Shape index distribution based local surface complexity applied to the human cortex, Med. Imag.: Image Proc. SPIE 9413, Orlando, Florida, February 21-26, 2015.

37. T. Connell†, M-A. Renaud†, J. Seuntjens, Investigations on scattering foil free beamlines and the development of the McGill University modulated electron radiotherapy program, Varian Research Symposium, Atlanta, Georgia, March 23-25, 2015 (poster presentation).

38. D.A. Moreno, A. Jesson, N. Subbanna, Z. Karimaghaloo, D.L. Arnold, D.L. Collins, T. Arbel, Diffeomorphic registration of healthy tissue priors to brain MRI for pathology segmentation, IEEE International Symposium on Biomedical Imaging (IEEE ISBI): From Nano to Macro, New York, New York, April 16-19, 2015.

39. E. Barlow-Krelina, M. Lysenko, N. Akbar, B. Aubert-Broche, D.L. Collins, E.A. Yeh, B. Banwell, C. Till, Neuropsychological assessment in pediatric-onset multiple sclerosis patients: Sensitivity of hand dexterity to TI and T2 lesion volume, Neuroinflammation Symposium, Toronto, Ontario, April 2015.

40. E. Alonso-Ortiz†, I.R. Levesque, G.B. Pike, ΔB0 correction for myelin water fraction imaging based on multi-slice MGRE acquisitions, Proc. 23rd Scientific Meeting of the ISMRM, Toronto, Ontario, p.444 (2015).

41. K. Nakamura, V.S. Fonov, N. Guizard, S. Narayanan, D.L. Arnold, D.L. Collins, Extending BrainWeb for evaluating methods of brain volume change: Simulation of central and peripheral brain atrophy, Proc. 23rd Scientific Meeting of the Society for Magnetic Resonance in Medicine (ISMRM), Toronto, Ontario, p.2492, May 30-June 05, 2015.

42. Z. Ahmed†, I.R. Levesque, DCE-MRI shape analysis using model-based classification shapes with NNLS, Proc. 23rd Scientific Meeting of the Society for Magnetic Resonance in Medicine (ISMRM), Toronto, Ontario, p.3066, May 30-June 05, 2015.

43. J.A. Rioux, I.R. Levesque, B.K. Rutt, Biexponential T1 relaxation at 7T: Characterization and impact on T1 mapping, Proc. 23rd Scientific Meeting of the Society for Magnetic Resonance in Medicine (ISMRM), Toronto, Ontario, p.3241, May 30-June 05, 2015.

44. B. De Leener, A. Roux, J. Touati, S. Levy, M. Taso, V.S. Fonov, D.L. Collins, V. Callot, J. Cohen-Adad, Template-based analysis of multi-parametric MRI data with the spinal cord toolbox, Proc. 23rd Scientific Meeting of the Society for Magnetic Resonance in Medicine (ISMRM), Toronto, Ontario, p.4437, May 30-June 05, 2015.

45. E. Barlow-Krelina, E.A. Yeh, M. Lysenko, N. Akbar, B. Aubert-Broche, D.L. Collins, B. Banwell, C. Till, The role of physical activity on brain volume and cognitive efficiency in pediatric-onset multiple sclerosis: Comparing strenuous and moderate activity, Canadian Psychological Association Convention, Ottawa, Ontario, June 04-06, 2015.

46. E. Barlow-Krelina, M. Lysenko, N. Akbar, B. Aubert-Broche, D.L. Collins, E.A. Yeh, B. Banwell, C. Till, Neuropsychological assessment in pediatric-onset multiple sclerosis patients: Sensitivity of hand dexterity to TI and T2 lesion volume, 45th Annual Meeting of the Jean Piaget Society. Toronto, Ontario, June 04-06, 2015.

47. M. Fan†, F. DeBlois, J. Thebaut, Quality control of TrueBeam VMAT FFF treatment deliveries with portal dosimetry and Eclipse, Proc. World Congress on Medical Physics and Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015.

48. J. Mullins†, K. Asiev, F. DeBlois, J. Seuntjens, A. Syme, Delivery of VMAT treatments with nonstandard SAD using dynamic trajectories, Proc. World Congress on Medical Physics and Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015.

49. L. Mirzakhanian†, V. Giusti, S.A. Enger, Investigation of the uncertainties involved in the low energy proton interaction in Geant4/MCNP6 for proton therapy applications, Proc. World Congress on Medical Physics and Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015.

50. P. Pater†, G. Bäckström†, M.F. Villegas, A. Ahnesjö, S.A. Enger, J. Seuntjens, Exploring RBE dependence on proton track angular incidence, Proc. World Congress on Medical Physics and Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015.

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51. G. Bäckström†, M.F. Villegas, S.A. Enger, A. Ahnesjö, Impact of the microdosimetric spread on cell survival

data analysis, Proc. World Congress on Medical Physics and Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015.

52. Y. Zeighami, M. Ulla, M. Dadar, Y. Iturria-Medina, K. Larcher, A.C. Evans, D.L. Collins, A. Dagher, Parkinson's disease targets an intrinsic brain network, Organization for Human Brain Mapping (OHBM), Honolulu, Hawaii, June 14-18, 2015.

53. D. Markel†, J. Larkin, P. Léger, I.R. Levesque, I. El Naqa, Temporally realistic manipulation a 4D biomechanical lung phantom for evaluation of simultaneous registration and segmentation, 57th Annual Meeting and Exhibition of the American Association of Physicists in Medicine, Anaheim, California, July 12-16, 2015 (Selected for Young Investigator Symposium).

54. M. Vallières†, A. Boustead†, S. Laberge, I.R. Levesque, I. El Naqa, A machine learning approach for creating texture-preserved MRI tumor models from clinical sequences, 57th Annual Meeting and Exhibition of the American Association of Physicists in Medicine, Anaheim, California, July 12-16, 2015.

55. P. Orban, S. Urchs, M. Savard, C. Madjar, A. Tam, L. Theroux, A. Evans, P. Rosa-Neto, D.L. Collins, J. Poirier, J. Breitner, P. Bellec, and the PREVENT-AD Research Group, Functional brain network subtypes are associated with AD biomarkers in an again high-risk cognitvely normal cohort: The Prevent-AD study, Alzheimer’s Association (AAIC), Washington D.C., July 18-23, 2015.

56. E. Barlow-Krelina M. Lysenko, N. Akbar, B. Aubert-Broche, D.L. Collins, E.A. Yeh, B. Banwell, C. Till, Physical activity in patients with pediatric- onset multiple sclerosis: Associations with brain volume and cognitive efficiency, 123rd Annual Convention of the American Psychological Association, Toronto, Ontario, August 06-09, 2015. Winner of the Blue Ribbon Award.

57. R. Giraud, V. Ta, N. Papadakis, D.L. Collins, P. Coupé, Optimisation de l’algorithme PatchMatch pour la segmentation de structures anatomiques, XXVe Colloque GRETSI - Traitement du Signal et des Images Lyon. Lyon, France. (ID160), September 2015.

58. M. Vallières†, C.R. Freeman, Z. Ahmed†, R. Turcotte, M. Hickeson, S. Skamene, K. Jeyaseelan, L. Hathout, M. Serban, S. Xing†, T. Powell, J. Seuntjens, I.R. Levesque, I. El Naqa, Early assessment of tumor aggressiveness using joint FDG-PET/MRI textural features: Prediction of prospective cohort and potential improvement using hypoxia and perfusion biomarkers, 57th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, San Antonio, Texas, October 18-21, 2015.

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APPENDIX XI.

INVITED PRESENTATIONS

by members of the Medical Physics Unit : 2015 calendar year (x 23) (in multiple author entries, the author who presented the paper is shown with an asterisk)

1. S.A. Enger, Medical radiation physics, brachytherapy, Monte Carlo simulations, patient specific dosimetry,

Soup & Science, Faculty of Science, Redpath Museum, McGill University, Montréal, Québec, January 12, 2015.

2. R. Richardson, New results on aging in humans, and their impact on radiation-induced senescence, Medical Physics, McGill University Health Centre, Montréal, Québec, March 14, 2015.

3. J. Kildea*, T. Hijal, L. Hendren, Addressing the pain of waiting: A health informatics approach, Oncology Grand Rounds, McGill University Health Centre, Montréal, Québec, March 2015.

4. H. Patrocinio, Physics of radiation therapy, Radiation Oncology Review Course, Sao Paolo, Brazil, March 2015.

5. J. Thebaut, Dose reconstruction-based patient specific QA for TrueBeam VMAT using trajectory log files, University of Nebraska Medical Centre, Omaha, Nebraska, March 2015.

6. R. Richardson*, L. Paterson, Investigating the radiation qualities of neutrons & biodosimetry at Canadian Nuclear Laboratories, Medical Physics, McGill University Health Centre, Montréal, Quebec, May 22, 2015.

7. J. Kildea, Database rudiments and clinical use, Continuing Education Program, World Congress on Medical Physics & Biomedical Engineering, June 07-12, 2015.

8. J. Seuntjens, IAEA-AAPM code of practice for the dosimetry of static small photon fields, American Association of Physicists in Medicine, 57th Annual Meeting. SAM Session Small Field Dosimetry, July 16, 2015.

9. J. Seuntjens, Standards for nonstandard photon beams, American Association of Physicists in Medicine, 57th Annual Meeting, SAM Session Radiation Standards for non-conventional beams, July 16, 2015.

10. J. Seuntjens, From ionizing radiation interactions to concepts of dosimetry of radiation therapy, Winter School Physics, Campinas, Brazil, July 30, 2015.

11. J. Seuntjens, Monte Carlo calculations for measurement dosimetry and radiation therapy treatment planning, Winter School Physics, Campinas, Brazil, July 30, 2015.

12. J. Seuntjens, The role of radiation dosimetry in the era of advanced radiation medicine, Conference in Medical Physics (ConfiMed), organized by graduate students, Campinas, Brazil, August 3, 2015.

13. J. Seuntjens, Physics in radiation medicine: Research, training and clinical role in the next decade, University of Toronto, Princess Margaret Hospital, Toronto, Ontario, August 21, 2015.

14. J. Seuntjens, Medical Physics programs at the Medical Physics Unit, McGill University and McGill University Health Centre, Montréal, Québec, September 22, 2015.

15. J. Kildea*, T. Hijal, L. Hendren, Realistic knowledge-based waiting times for radiation oncology patients, Patient Safety Week, McGill University Health Centre, Montréal, Québec, October 2015.

16. W. Parker, Glen site deployment: Role of medical physics, Centre Hospitalier de L’universite de Montreal, October 2015, Montreal, Quebec.

17. N. Ybarra, Collaborative radiobiological experiments with Canadian Nuclear Laboratories involving neutron exposures, November 18-19, 2015.

18. J. Seuntjens, Physics and Cancer Therapeutics, CRP Research Day, Research Institute-McGill University Health Centre, Montréal, Québec, November 27, 2015.

19. R. Richardson, F. Flegal*, Canadian emergency biodosimetry dose response network, Medical Physics, McGill University Health Centre, Montréal, Quebec, November 27, 2015.

20. J. Seuntjens. “Uncertainties associated with using the small field code of practice” Workshop on the Implementation of the International Code of Practice for the Dosimetry of Static Small Fields used in Radiotherapy IAEA - Argonne Small Filed Dosimetry; Training Course on Small Field Dosimetry E2-TR-51583 Chicago, Illinois, December 10-14, 2015.

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21. J. Seuntjens, Introduction to the new IAEA/AAPM code of practice for dosimetry of static small photon fields,

Workshop on the Implementation of the International Code of Practice for the Dosimetry of Static Small Fields used in Radiotherapy IAEA - Argonne Small Filed Dosimetry; Training Course on Small Field Dosimetry E2-TR-51583, Chicago, Illinois, December 10-14, 2015.

22. J. Seuntjens, Absorbed dose standards for small fields, Workshop on the Implementation of the International Code of Practice for the Dosimetry of Static Small Fields used in Radiotherapy IAEA - Argonne Small Filed Dosimetry; Training Course on Small Field Dosimetry E2-TR-51583, Chicago, Illinois, December 10-14, 2015.

23. J. Seuntjens, Physics of small fields, Workshop on the Implementation of the International Code of Practice for the Dosimetry of Static Small Fields used in Radiotherapy IAEA - Argonne Small Filed Dosimetry; Training Course on Small Field Dosimetry E2-TR-51583 Chicago, Illinois, December 10-14, 2015.

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APPENDIX XII.

CONFERENCE & SEMINAR PRESENTATIONS

by members of the Medical Physics Unit : 2015 calendar year (x 100) (presenter is indicated by an asterisk *)

(the names of staff members of the MPU are underlined, students are indicated by †)

1. S. Hyung Kim, V. Fonov, D.L. Collins, G. Gerig, IBIS Network, M.A. Styner, Shape index distribution based local surface complexity applied to the human cortex, SPIE Medical Imaging 2015: Image Processing, Orlando, Florida, February 21-26, 2015; 9413.

2. T. Connell†, M-A. Renaud†, J. Seuntjens, Investigations on scattering foil free beamlines and the development of the McGill University modulated electron radiotherapy program, Varian Research Symposium, Atlanta, Georgia, March 23-25, 2015; poster.

3. J. Mullins†*, K. Asiev, F. DeBlois, J. Seuntjens, A. Syme, Implementation and validation of trajectory-based radiotherapy with Eclipse treatment planning and TrueBeam Developer Mode, Varian Research Partners Meeting, Atlanta, Georgia, March 23-27, 2015.

4. J. Kildea, L. Hendren, A. Joseph†, T. Hijal, J. Seuntjens, Automated electronic health record auditing, Atlanta, Georgia, March 23-27, 2015.

5. J. Wang†, J. Seuntjens, Validation of MC track structure codes against experiments in amorphous ice, NSERC-CREATE Workshop "From Track Structure to Clinical Outcomes and Reverse", March 30-31, 2015, Montreal; oral.

6. P. Pater†, G. Bäckström†, M.F. Villegas, A. Ahnesjö, S. Enger, J. Seuntjens, Simulation of clusters of DNA lesions using a probabilistic approach, NSERC-CREATE Workshop "From Track Structure to Clinical Outcomes and Reverse", March 30-31, 2015, Montreal; oral.

7. D.A. Moreno, A. Jesson, N. Subbanna, Z. Karimaghaloo, L.D. Arnold, D.L. Collins, T. Arbel, Diffeomorphic registration of healthy tissue priors to brain MRI for pathology segmentation, IEEE International Symposium on Biomedical Imaging (IEEE ISBI): From Nano to Macro. New York, New York, April 16-19, 2015.

8. S. Aldelaijan*, S. Devic, M. Shehadeh, F. Alzorkany, K. Al-Hadyan, G. Alsbeih, J. Seuntjens, B. Moftah, Dose calibration and monitoring for radiobiological experiments with low energy proton beams, 3rd Forum of the European Society for Radiotherapy & Oncology (ESTRO), Barcelona, Spain, April 24-28, 2015.

9. P. Pater†, G. Bäckström†, M.F. Villegas, A. Ahnesjö, S. Enger, J. Seuntjens, Initial DNA damage patterns with Monte Carlo tracks and ionization clusters, 3rd Forum of the European Society for Radiotherapy & Oncology (ESTRO), Barcelona, Spain, April 24-28, 2015.

10. M.F. Villegas, G. Bäckström†, N. Tilly, S. Enger, A. Ahnesjö, Impact of the microdosimetric spread on LQ-parameterization of cell survival data for protons and Co-60 photons, 3rd Forum of the European Society for Radiotherapy & Oncology (ESTRO), Barcelona, Spain, April 24-28, 2015.

11. N. Tomic, C. Quintero†, F. DeBlois, J. Seuntjens, S. Devic, Radiochromic film based dose measurements during radiotherapy 4D CT-simulation, 3rd Forum of the European Society for Radiotherapy & Oncology (ESTRO), Barcelona, Spain, April 24-28, 2015.

12. L. Liang, H. Bekerat, N. Tomic, F. DeBlois, T. Vuong, S. Devic, A. Nobah, M. Mohiuddin, B. Moftah, Optimal beam quality for linac-based spatially fractionated grid radiation therapy (SFGRT), 3rd Forum of the European Society for Radiotherapy & Oncology (ESTRO), Barcelona, Spain, April 24-28, 2015.

13. S. Devic, H. Mohammed, S. Aldelaijan, N. Tomic, J. Seuntjens, F. DeBlois, S. Lehnert, S. Faria FDG based glycolytic biological target volume: Warburg effect vs. hypoxia, 3rd Forum of the European Society for Radiotherapy & Oncology (ESTRO), Barcelona, Spain, April 24-28, 2015.

14. J. Coates†, A.K. Jeyaseelan, N. Ybarra, J. Tao, M. David, S. Faria, L. Souhami, F. Cury, M. Duclos, I. El Naqa, Evaluation of NTCP radiogenomic modeling frameworks in hypofractionated prostate cancer patients, 3rd Forum of the European Society for Radiotherapy & Oncology (ESTRO), Barcelona, Spain, April 24-28, 2015.

15. M. Renaud†, J. Seuntjens, Mixed beam inverse planning strategies, 3rd Forum of the European Society for Radiotherapy & Oncology (ESTRO), Barcelona, Spain, April 24-28, 2015.

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16. J. Seuntjens, L Beaulieu, D.L Collins, P. Despres, S. Devic, I. El Naqa, J. Nadeau, G.B. Pike, A. Reader, The

CREATE Medical Physics Research Training Network: Training of new generation innovators in medical physics, 3rd Forum of the European Society for Radiotherapy & Oncology (ESTRO), Barcelona, Spain, April 24-28, 2015.

17. P. Papaconstadopoulos†, L. Archambault, J. Seuntjens, On the accuaracy of the Exradin W1 and the spectrum calibration method in scintillation dosimetry for small fields, 3rd Forum of the European Society for Radiotherapy & Oncology (ESTRO), Barcelona, Spain, April 24-28, 2015.

18. B. Moftah*, A. Basfar, K. Rabaeh, A. Almousa, M.A. Al Kafi, S. Devic, Radiation response of an improved optical CT based 3D gel dosimeter for radiation therapy quality assurance, 3rd Forum of the European Society for Radiotherapy & Oncology (ESTRO), Barcelona, Spain, April 24-28, 2015.

19. T. Vuong*, T. Niazi, S. Devic, Role of endoluminal brachytherapy for rectal cancer: current status and challenges, 3rd Forum of the European Society for Radiotherapy & Oncology (ESTRO), Barcelona, Spain, April 24-28, 2015.

20. P. Watson†, M. Popovic, J. Seuntjens, An in-air Monte Carlo investigation of a miniature low energy x-ray tube, 3rd Forum of the European Society for Radiotherapy & Oncology (ESTRO), Barcelona, Spain, April 24-28, 2015.

21. M. Serban, M.A. Renaud†, R. Maglieri†, A. Alexander, C.R. Freeman, Eliminating dosimetric uncertainties in tomotherapy delivery in sarcoma patients planned using Monte Carlo techniques, 3rd Forum of the European Society for Radiotherapy & Oncology (ESTRO), Barcelona, Spain, April 24-28, 2015.

22. E. Barlow-Krelina, M. Lysenko, N. Akbar, B. Aubert-Broche, D.L. Collins, E.A. Yeh, B. Banwell, C. Till, Neuropsychological assessment in pediatric-onset multiple sclerosis patients: Sensitivity of hand dexterity to TI and T2 lesion volume, 6th Annual Neuroinflammation Symposium & MB-ON endMS RRTC Retreat, Toronto, Ontario, April 30-May 01, 2015.

23. S. Devic, Endorectal brachytherapy: Dosimetry and QA, Head & Neck and Lower GI Cancer Brachytherapy Workshop, Montréal, Québec, May 15-16, 2015.

24. Z. Ahmed†, I.R. Levesque, DCE-MRI analysis using model-based classification shapes with non-negative least-squares, Proceedings of the 23rd ISMRM Annual Meeting, Toronto, Ontario, May 30-June 05, 2015.

25. E. Alonso-Ortiz†, I.R. Levesque, G.B. Pike, ΔB0 correction for myelin water fraction imaging based on multi-

slice MGRE acquisitions, Proceedings of the 23rd ISMRM Annual Meeting, Toronto, Ontario, May 30-June 05, 2015.

26. K. Nakamura, V.S. Fonov, N. Guizard, S. Narayanan, D.L. Arnold, D.L. Collins, Extending BrainWeb for evaluating methods of brain volume change: Simulation of central and peripheral brain atrophy, Proceedings of the 23rd ISMRM Annual Meeting, Toronto, Ontario, May 30-June 05, 2015.

27. B. De Leener, A. Roux, J. Touati, S. Levy, M. Taso, V.S. Fonov, D.L. Collins, V. Callot, J. Cohen-Adad, Template-based analysis of multi-parametric MRI data with the spinal cord toolbox, Proceedings of the 23rd ISMRM Annual Meeting, Toronto, Ontario, May 30-June 05, 2015, pp. 4437.

28. E. Barlow-Krelina, E.A. Yeh, M. Lysenko, N. Akbar, B. Aubert-Broche, D.L. Collins, B. Banwell, C. Till, The role of physical activity on brain volume and cognitive efficiency in pediatric-onset multiple sclerosis: Comparing strenuous and moderate activity, Canadian Psychological Association Convention, Ottawa, Ontario, June 04-06, 2015.

29. E. Barlow-Krelina, M. Lysenko, N. Akbar, B. Aubert-Broche, D.L. Collins, E.A. Yeh, B. Banwell, C. Till, Neuropsychological assessment in pediatric-onset multiple sclerosis patients: Sensitivity of hand dexterity to TI and T2 lesion volume, Jean Piaget Society Conference, Toronto, Ontario, June 04-06, 2015.

30. J. Seuntjens, The modern physicist tool box: How to choose between current dosimeters, IUPESM World Congress, Toronto, Ontario, June 07-12, 2015. Oral presentation MPE09.1.

31. J. Kildea, Database rudiments and clinical use, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015. Oral presentation MPE05.1.

32. B. Moftah, J. Seuntjens, Radiochromic film based dose calibration and monitoring for radiobiological experiments using low energy proton beams, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015. Oral presentation SP1402.4.

33. C. Soffientini, I. El Naqa, GMM guided automated Level Set algorithm for PET image segmentation, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015. Poster presentation PS04.088.

34. I. El Naqa, Evaluation and visualization of radiogenomic modeling frameworks for the prediction of normal tissue toxicities, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, June 07-12, 2015. Oral presentation SP046.6.

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35. J. Mullins†*, K. Asiev, F. DeBlois, J. Seuntjens, A. Syme, Delivery of VMAT treatments with non-standard

SAD using dynamic trajectories, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015.

36. S.A. Enger, Impact of the microdosimetric spread on cell survival data analysis, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015.

37. P. Watson†*, M. Popovic, J. Seuntjens, A study of uncertainties in the half-value measurement of a kV miniature x-ray source, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015.

38. M. Fan†, F. DeBlois, J. Thebaut*, Use of Varian trajectory log files for patient specific quality control of TrueBeam VMAT FFF treatment deliveries with portal dosimetry and Eclipse, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015.

39. E. Christiansen†, B. Muir, J. Belec, E. Vandervoort, Determination of ion chamber correction factors for small composite fields used by the CyberKnife radiosurgery system, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015. Poster presentation PS04.021.

40. Y. Zlateva†, I. El Naqa, Cherenkov emission dosimetry for electron beam radiotherapy: A Monte Carlo feasibility study of absolute dose prediction, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015. Oral presentation SP069.2.

41. L. Mirzakhanian†, V. Giusti, S.A. Enger, Investigation of the uncertainties involved in the low energy proton interaction in different MC-codes for proton therapy application, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015. Oral presentation – SP048.6.

42. D. Markel†, J. Larkin, P. Leger, I.R. Levesque, I. El Naqa, Development of a multi-modality 4D biomechanical phantom for evaluation of simultaneous registration/segmentation algorithms, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015. Oral presentation – SP072.6.

43. J. Perez†, N. Ybarra, F. Chagnon, O. Lesur, I. EL Naqa, Quantitative image analysis of fluorescence endomicroscopy video sequences for mesenchymal stem cell tracking in regenerative lung treatment, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015. Oral presentation – SP096.2.

44. P. Watson†, M. Popovic, J. Seuntjens, A study of uncertainties in the half-value layer measurement of a kV miniature x-ray source, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, June 07-12, 2015. Oral presentation - SP068.

45. J. Renaud†, A. Sarfehnia, J. Seuntjens, On the practical use of calorimetry for routine absolute dosimetry in the radiotherapy clinic, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015. Oral presentation - SP163.6.

46. P. Pater†, I. El Naqa, S. Enger, J. Seuntjens, Exploring RBE dependence on proton track angular incidence, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, Ontario, June 07-12, 2015. Oral presentation - SP076.5.

47. Y. Zeighami, M. Ulla, *M. Dadar, Y. Iturria-Medina, K. Larcher, A.C. Evans, D.L. Collins, A. Dagher, Parkinson's disease targets an intrinsic brain network, Organization for Human Brain Mapping (OHBM), Honolulu, Hawaii, June 14-18, 2015.

48. L. Mirzakhanian†, V. Giusti, S.A. Enger, Study of uncertainties involved in secondary particles production in Geant4/MCNP6 Monte Carlo codes for proton therapy application, HPCS2015, Montreal, Quebec, June 15-19, 2015. Poster no. 36.

49. P. Watson†, M. Popovic, J. Seuntjens, An in-air and in-water investigation of the INTRABEAM system dosimetry using a Monte Carlo source model, Zeiss INTRABEAM User Meeting, Mannheim, Germany, July 09-10, 2015.

50. J. Seuntjens, L. Beaulieu, D.L. Collins, P. Despres, S. Devic, I. El Naqa, J. Nadeau, G.B. Pike, A. Reader, The CREATE Medical Physics Research Training Network: Training of new generation innovators, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015.

51. L Liang, H. Bekerat, N. Tomic, F. DeBlois, S. Devic, M. Morcos†, M. Popovic, P Watson†, J. Seuntjens, Impact of the radiochromic film energy response on dose measurements of low energy electronic brachytherapy source, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015.

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52. E. Christiansen†, M. Muir, J. Belec, E. Vandervoort, Determination of intermediate correction factors for

three dosimeters in small composite photon fields used in robotic radiosurgery, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation.

53. M. Vallières†, A. Diamant-Boustead†, S. Laberge, I.R. Levesque, I. El Naqa, A machine learning approach for creating texture-preserved MRI tumor, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, SU-J-E-250; Med. Phys. 42(6), 3323.

54. L. Mirzakhanian†, V. Giusti, S.A. Enger, Investigation of the uncertainties involved in secondary neutron/gamma production in Geant4/MCNP6 Monte Carlo Codes for proton therapy application, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, SU-E-T-521; Med. Phys. 42(6), 3455.

55. Z. Ahmed†, I. El Naqa, I.R. Levesque, A constrained linear reference region model for DCE-MRI, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation TH-CD-207-03; Med. Phys. 42(6), 3735.

56. P. Pater†, G. Bäckström†, M.F. Villegas, A. Ahnesjö, S. Enger, J. Seuntjens, I. El Naqa, On the value of LET as a radiation quality descriptor in RBE-LET relationships, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation SU-E-T-581; Med. Phys. 42(6), 3469.

57. P. Pater†, G. Bäckström†, M.F. Villegas, A. Ahnesjö, S. Enger, J. Seuntjens, I. El Naqa, Influence of proton track-cell nucleus incidence angle on relative biological effectiveness, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation SU-E-T-494; Med. Phys. 42(6), 3448.

58. D. Markel†, J. Larkin, P. Leger, I.R. Levesque, I. El Naqa, Temporally realistic manipulation a 4D biomechanical lung phantom for evaluation, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 201, oral presentation (Young Investigator competition) MO-AB-BRA-09; Med. Phys. 42(6), 3549.

59. A. Toltz†, M. Hoesl, J. Schuemann, J. Seuntjens, H.M. Lu, H. Paganetti, In-vivo diode dosimetry proton therapy range verification validation study for pediatric CSI, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation SU-E-T-524; Med. Phys. 42(6), 3455.

60. L. Liang, H. Bekerat, N. Tomic, F. DeBlois, S. Devic, M. Morcos, M. Popovic, P. Watson†, J. Seuntjens, Impact of the radiochromic film energy response on dose measurements of low energy electronic brachytherapy sources, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation SU-E-T-462; Med. Phys. 42(6), 3440.

61. P. Papaconstadopoulos†, L. Archambault, J. Seuntjens, Experimental investigation on the accuracy of plastic scintillation dosimeters in small fields, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation SU-C-304-03; Med. Phys. 42(6), 3190.

62. Y. Zlateva†, I. El Naqa, Cherenkov emission dosimetry: Feasibility for electron radiotherapy, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, BEST IN PHYSICS (THERAPY) oral presentation MO-FG-303-2; Med. Phys. 42(6), 3567.

63. S. Aldelaijan, F. Alzorkany, B. Moftah, F. Alrumayan, J. Seuntjens, D. Lewis, S. Devic, Radiochromic film quenching effect reduction for proton beam dosimetry, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, submitted for John R. Cameron Young Investigator Symposium: oral presentation SU-E-T-665; Med. Phys. 42(6), 3489.

64. J. Renaud†, A. Sarfehnia, J. Seuntjens, Development of a probe-format graphite calorimeter for practical clinical dosimetry: Numerical design optimization, prototyping, and experimental proof-of-concept, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation WE-AB-BRB-01; Med. Phys. 42(6), 3649.

65. M-A. Renaud†, R. Flynn, J. Seuntjens, S. Enger, Rotating shield high dose rate brachytherapy with 153Gd and 75Se isotopes 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation TU-AB-201-08; Med. Phys. 42(6), 3595.

66. S. Hickling†, P. Léger, I. El Naqa, Amplitude and frequency characteristics of acoustic waves induced following radiotherapy linear accelerator irradiation. 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation TH-CD-304-06; Med. Phys. 42(6), 3723.

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67. F. Liu, A. Tai, P. Lee, T. Biswas, G. Ding, I. El Naqa, J. Grimm, A. Jackson, F. Kong, T. LaCouture, B. Loo,

M. Miften, T. Solberg, X. Li, Tumor control probability modeling for stereotactic body radiation therapy of early-stage lung cancer using multiple bio-physical models, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation TH-AB-304-04; Med. Phys. 42(6), 3701.

68. I. El Naqa, Cranial TCP/NTCP modeling insights and caveats, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation WE-F-304-05; Med. Phys. 42(6), 3685.

69. I. El Naqa, Radiomics and the coming pan-omics revolution, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation TU-G-303-04; Med. Phys. 42(6), 3632.

70. J. Seuntjens, L. Beaulieu, D.L. Collins, P. Despres, S. Devic, I. El Naqa, J. Nadeau, G.B. Pike, A. Reader, The CREATE Medical Physics Research Training Network: Training of new generation innovators, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation MO-DE-BRA-04; Med. Phys. 42(6), 3557.

71. I. Das, J. Seuntjens, Small field dosimetry: Overview of AAPM TG-155 and the IAEA-AAPM code of practice, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation TH-A-213-0; Med. Phys. 42(6), 3700.

72. M. McEwen, R. Tosh, A. Sarfehnia, J. Seuntjens, Reference dosimetry for beam modalities other than MV photons, 57th annual meeting of the American Association of Physicists in Medicine (AAPM), Anaheim, California, July 12-16, 2015, oral presentation TH-E-304-0; Med. Phys. 42(6), 3739.

73. P. Orban, S. Urchs, M. Savard, C. Madjar, A. Tam, L. Theroux, A. Evans, P. Rosa-Neto, D.L. Collins, J. Poirier, J. Breitner, P. Bellec, and the PREVENT-AD Research Group, Functional brain network subtypes are associated with AD biomarkers in an again high-risk cognitively normal cohort – the Prevent-AD study, Alzheimer’s Association International Conference (AAIC), Washington D.C., July 18-23, 2015.

74. E. Barlow-Krelina, M. Lysenko, N. Akbar, B. Aubert-Broche, D.L. Collins, E.A. Yeh, B. Banwell, C. Till, Physical activity in patients with pediatric-onset multiple sclerosis: Associations with brain volume and cognitive efficiency, 123rd annual convention of the American Psychological Association, Toronto, Ontario, August 06-09, 2015. Winner of the BLUE RIBBON AWARD.

75. M. Keshavarz†, J. Kildea, A hybrid application for cancer patients, MUHC Summer Student Symposium, Montreal, Quebec, August 2015.

76. R. Giraud, V. Ta, N. Papadakis, D.L. Collins, P. Coupé, Optimisation de l’algorithme PatchMatch pour la segmentation de structures anatomiques, XXVe Colloque GRETSI: Traitement du Signal et des Images, Lyon, France, September 08-11, 2015, ID160.

77. S. Vallières†, D. Gonçalves†, J. Seuntjens, J. Nadeau, Dose enhancement with nanoparticles in radiation therapy using high Z materials, Regroupement de Recherche en Nanosciences (R2Nanos), INRS - Institut Armand-Frappier, Montreal, Quebec, September 23, 2015, oral presentation.

78. P. Papaconstadopoulos†, Small field dosimetry, Career Paths and Industrial Workshop & Symposium, Montreal, Quebec, September 24-25, 2015, oral presentation.

79. J. Renaud†, Calorimeters for radiation dosimetry: A historical overview, Career Paths and Industrial Workshop & Symposium, Montreal, QC, September 24-25, 2015, oral presentation.

80. M. Carrier-Vallieres†, RADIOMICS: Mais où est donc car ni or? (Who, What, Why, Where, When), Career Paths and Industrial Workshop & Symposium, Montreal, QC, September 24-25, 2015, oral presentation – Winner of the competition “ The Rising Star in Medical Physics Symposium” of the MPRTN.

81. S. Lee†, Towards patient-specific outcome prediction: A graphical approach, Career Paths and Industrial Workshop & Symposium, Montreal, QC, September 24-25, 2015, oral presentation.

82. D. Markel†, Automated tools: Segmentation, registration and validation techniques, Career Paths and Industrial Workshop & Symposium, Montreal, QC, September 24-25, 2015, oral presentation.

83. A. Toltz†, M. Hoesl, J. Schuemann, J. Seuntjens, H.M. Lu, H. Paganetti, A calibration study for an in vivo proton therapy range verification technique for pediatric craniospinal irradiation using time resolved diode dosimetry, PPRIG Proton Therapy Physics Workshop, National Physical Laboratory, Teddington, England, October 01-02, 2015, presentation.

84. T. Vuong, R. Nout, T. Niazi, A. Garant, A. Bujold, A-G. Martin, S. Ferland, G. Stroian, J. Thebaut, A. Syme, S. Devic, Radiation therapy as a curative modality for patients with rectal cancer, 57th annual meeting of the American Society for Therapeutic Radiation Oncology (ASTRO), Henry B. Gonzalez Convention Center, San Antonio, Texas, October 18-21, 2015.

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85. M. Carrier-Vallières†, C.R. Freeman, Z. Ahmed†, R. Turcotte, M. Hickeson, S.R. Skamene, K. Jeyaseelan, L.

Hathout, M. Serban, S. Xing†, T.I. Powell†, J. Seuntjens, I.R. Levesque, I. El Naqa, Early assessment of tumor aggressiveness using joint FDG-PET/MRI textural features: Prediction of prospective cohort and potential improvement using hypoxia and perfusion biomarkers, 57th annual meeting of the American Society for Therapeutic Radiation Oncology (ASTRO), Henry B. Gonzalez Convention Center, San Antonio, Texas, October 18-21, 2015, oral presentation - award.

86. N. Ybarra, S. Lee†, L.M. Wang, O. Maria, K. Jeyaseelan, J. Perez†, M. Serban, I. El Naqa, Effects of GM-CSF and mesenchymal stem cells administration on subregional response in a rat model of radiation-induced lung injury, 57th annual meeting of the American Society for Therapeutic Radiation Oncology (ASTRO), Henry B. Gonzalez Convention Center, San Antonio, Texas, October 18-21, 2015, oral presentation.

87. S. Lee†, N. Ybarra, K. Jeyaseelan, S. Faria, N. Kopek, I. El Naqa, Bayesian network representation of radiation pneumonitis onset after hypofractionated stereotactic body radiation therapy (SBRT) for lung cancer, 57th annual meeting of the American Society for Therapeutic Radiation Oncology (ASTRO), Henry B. Gonzalez Convention Center, San Antonio, Texas, October 18-21, 2015, oral presentation.

88. E. Cloutier†, Characterization of the Cd/Se quantum dots response when irradiated at ionising energies for a dosimetry application, 51st annual Canadian Undergraduate Physics Conference (CUPC), Trent University (Symons Campus), Peterborough, Ontario, October 22-25, 2015, presentation prize.

89. M. Vallières†, C.R. Freeman, R. Turcotte, J. Seuntjens, I. El Naqa, Early prediction of lung metastases in soft-tissue sarcomas of the extremities using joint FDG-PET and MRI textural features, annual meeting of the Connective Tissue Oncology Socciety (CTOS), Salt Lake City, Utah, November 04-07, 2015, poster presentation.

90. L. Montgomery†, J. Kildea, Radiotherapy incident management at the McGill University Health Centre: Standardization, workflow and collaboration, Cancer Research Program: Research Day, McGill University Health Centre (Glen Site), Montreal, Quebec, November 27, 2015, oral presentation.

91. A. Joseph†, J. Kildea, Realistic knowledge-based waiting times for radiotherapy patients: Addressing the pain of waiting, Cancer Research Program: Research Day, McGill University Health Centre (Glen Site), Montreal, Quebec, November 27, 2015, oral presentation.

92. S. Xing†, C.R. Freeman, S. Jung, I. Levesque, Automated segmentation of soft tissue sarcoma into distinct pathological regions using diffusion and T2 relaxation, Cancer Research Program: Research Day, McGill University Health Centre (Glen Site), Montreal, Quebec, November 27, 2015, oral presentation.

93. S. Dobri†, S. Enger, Development of a novel interferometry-based radiation detector, Cancer Research Program: Research Day, McGill University Health Centre (Glen Site), Montreal, Quebec, November 27, 2015, oral presentation.

94. Z. Ahmed†, I.R. Levesque, Predicting therapy response using perfusion MRI and pattern recognition, Cancer Research Program: Research Day, McGill University Health Centre (Glen Site), Montreal, Quebec, November 27, 2015, oral presentation.

95. K. O’Grady†, S. Davis, J. Seuntjens, Creation of a Monte Carlo TrueBeam model by reproducing Varian phase space data, annual workshop of the Association Québecoise des Physicien(ne)s Médicaux Cliniques (AQPMC), Montreal, Quebec, December 04, 2015.

96. S. Xing†, C.R. Freeman, S. Jung, I. Levesque, Automated segmentation of soft tissue sarcoma into distinct pathological regions using the apparent diffusion coefficient and T2 relaxation, annual workshop of the Association Québecoise des Physicien(ne)s Médicaux Cliniques (AQPMC), Montreal, Quebec, December 04, 2015 – Student Day, oral presentation.

97. Z. Ahmed†, I. Levesque, Predicting cancer therapy response with DCE-MRI, annual workshop of the Association Québecoise des Physicien(ne)s Médicaux Cliniques (AQPMC), Montreal, Quebec, December 04, 2015 – Student Day, oral presentation.

98. P. Watson†, J. Seuntjens, Effect of M and N-shell averaging in atomic relaxations for kV dosimetry, annual workshop of the Association Québecoise des Physicien(ne)s Médicaux Cliniques (AQPMC), Montreal, Quebec, December 04, 2015 – Student Day, oral presentation.

99. A. Joseph†, J. Kildea, Realistic knowledge-based waiting times for radiotherapy patients - addressing the pain of waiting, annual workshop of the Association Québecoise des Physicien(ne)s Médicaux Cliniques (AQPMC), Montreal, Quebec, December 04, 2015 – Student Day, oral presentation.

100. L. Montgomery†, J. Kildea, Radiotherapy incident management at McGill: Standardization, workflow, and collaboration, annual workshop of the Association Québecoise des Physicien(ne)s Médicaux Cliniques (AQPMC), Montreal, Quebec, December 04, 2015 – Student Day, oral presentation.

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APPENDIX XIII.

NEW & ONGOING GRANTS

held by MPU FACULTY MEMBERS in 2015

Grants are generally attained under the auspices of the grantee's primary department, i.e., either through McGill University (Oncology or Neurology & Neurosurgery)

or the McGill University Health Center (Medical Physics).

[Amounts listed are annual unless otherwise stated] COLLINS, D.L.

D.L. Collins et al. Entre le laboratoire et le chevet: Validation de biomarquers optimizes par resonance magnétique pour le diagnostique Clinique précoce et le prognostique dans la maladie d’Alzheimer Fonds de recherche du Québec (FRQ), FRSQ-Pfizer (2012-2015) ................................................................................................................................................. $199,600 K. Siddiqi, D.L. Collins et al. Medical image analysis Natural Sciences & Engineering Research Council (NSERC), CREATE grant (2012-2017) ................................................................................................................................................. $330,000 J. Seuntjens, D.L. Collins et al. Medical physics research training network (MRPTN) Natural Sciences & Engineering Research Council (NSERC), CREATE grant (2013-2019) ................................................................................................................................................. $333,333 L. Fellows, D.L. Collins, N. Mayo, M. Brouillette Brain imaging for monitoring and predicting response to cognitive training in HIV-associated neurocognitive disorder Canadian Institute for Health Research (CIHR), HIV Clinical Trials Network – Pilot Program (2014-2015) ................................................................................................................................................... $50,000 Alain Dagher, D.L.Collins MRI biomarkers for prediction of cognitive decline in AD and PD Alzheimer’s Association / Michael J. Fox Foundation / W. Garfield Weston Foundation (2014-2016) ................................................................................................................................................... $75,000 D.L. Collins et al Analysis of atrophy in pediatric-onset MS MS Society of Canada, MSSC Grant (2014-2017) ................................................................................................................................................. $120,093 F. Beg, P. Bellec, D.L. Collins, A.C. Evans, et al CBRAIN: Canadian brain research and informatics platform Brain Canada, Support Grant (total grant $3,000,000) (2014-2017) ................................................................................................................................................... $40,000

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H. Chertkow, D.L. Collins, et al (~200) Canadian Consortium for Neurodegeneration and Aging Canadian Institute for Health Research (CIHR) – CCNA (total grant $31.55 million) (2014-2019) ............................................................................................................................................................. $0 N. Yoganathan, D.L.Collins, D. Stanimirovic, B. Chakravarthy, J. Soucy, P. Rosa-Neto, M. Waterson, J. Gillard Drug delivery across the human blood-brain barrier (total grant $1,496,800) Brain Canada: CQDM (2015-2018) .................................................................................................................................................... $50,000 T. Dyrby, K. Skak Madsen, W. Baaré, S. Eskildsen, M. Ptito, M. Burke, D.L. Collins The cellular substrates of brain maturation changes Canadian Institute for Health Research (CIHR): The Danish Council for Independent Research (as co-applicant) (2015-2018) ............................................................................................................................................................. $0 D.L. Collins Image registration for image guided surgery Natural Sciences & Engineering Research Council (NSERC) (2015-2020) .................................................................................................................................................... $94,000 PI: J. Cohen-Adad; collaborators: Arnold, B. De Leener, S. Nadeau, N. Stikov, D.L. Collins, T. Duval, B. Perraud, R. Topfer, D. Côté, N. Lopez-Rios, S. Rossignol Shifting the paradigm of spinal cord quantitative MRI (2015-2020) .................................................................................................................................................. $128,891 J. Breitner, J. Poirier, S. Gautier, P. Rosa, A.C. Evans, P.E. Etienne, D.L. Collins, P. Bellec, G. Multhaup, R. Hoge Proof of concept: Trial of Probucol, an inducer of apoE, for prevention of Alzheimer's dementia Weston Hospital Institute: Early Phase Clinical Trials Program 2014 (2015-2020) .................................................................................................................................................... $30,000 D.L. Collins, K. Petreeca, T. Arbel, M. Descoteaux, G. Fichtinger, T. Peters, H. Rivaz A collaborative platform for image guided neurosurgery Canadian Institute for Health Research (CIHR): Collaborative Health Research Projects (NSERC Partnered) (2015-2018) .................................................................................................................................................. $193,333 D. Arnold, J. Simon, C. Guttmann, J. Wolinsky, N. De Stefano, F. Barkhof, M.P. Sormani, G. Cutter, D.L. Collins, L. Kappos, O. Ciccarelli, D. Chard, S. Narayanan Progessive MS Alliance: Collaborative Network Award. (as co-applicant), (2015-2016) .................................................................................................................................................... $50,000 DEBLOIS, F.

F. DeBlois (co-applicant) et al. 3D patient surface scanner development SMBD-Jewish General Hospital Foundation, grant (total grant $25,000) (2015-2017) ................................................................................................................................................... $12,500

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F. DeBlois (co-applicant) et al. Rectal applicator development Xoft Research Development grant (total grant $20,000) (2015-2017) ................................................................................................................................................... $10,000

DEVIC, S.

S. Devic (PI) Radiochromic film dosimetry Natural Sciences & Engineering Research Council (NSERC), discovery grant (total grant $140,000) (2015-2020) ................................................................................................................................................... $28,000 S. Devic Dosimetrie à film radiochromique Fonds de la Recherche en Santé du Québec (FRSQ) Bourse de chercheur-boursier Senior (total grant $265,367) (2013-2017) ................................................................................................................................................... $66,341 J. Seuntjens, S. Devic, et al Medical Physics Research Training Network (MPRTN) Natural Sciences & Engineering Research Council – Collaborative Research & Training Experience (NSERC-CREATE), CREATE grant (total $1,650,000) (2013-2019) ................................................................................................................................................ $333,333

ENGER, Shirin

S. Enger Start-up grant Simone & Morris Fast Award for Oncology, start-up (total $150,000) (2014-2019) .................................................................................................................................................. $30,000 S. Enger Monte Carlo track structure applications in microdosimetry and radiation response Natural Sciences & Engineering Research Council (total $95,000) (2014-2019) .................................................................................................................................................. $19,000 S. Enger Radiation source and detector development for use in Medical Radiation Physics Canadian Foundation for Innovation (CFI) – John L. Evans Leaders Fund, McGill University & Research Institute-McGill University Health Centre inter-institutional grant (total $195,262) (2016-2021) .................................................................................................................................................... $39,052

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KILDEA, J.

J. Seuntjens, M. Evans, J. Kildea Research collaboration: Radiation protection for neutrons Canadian Nuclear Safety Commission (CNSC), student support (2013-2014) ................................................................................................................................................... $15,000 J. Seuntjens, M. Evans, J. Kildea Research collaboration: Radiation protection for neutrons Canadian Nuclear Safety Commission (CNSC), student support (2014-2015) ................................................................................................................................................... $15,000 J. Kildea Graduate student support Canadian Patient Safety Institute (CPSI), (matching funds from MRPTN-CREATE grant) (2013-2014) ................................................................................................................................................... $15,000 J. Kildea Graduate student support Canadian Patient Safety Institute (CPSI), (matching funds from MRPTN-CREATE grant) (2014-2015) ................................................................................................................................................... $15,000 J. Kildea et al. Patient education material Rossy Cancer Network, grant (2014) ............................................................................................................................................................ $20,000

LEHNERT, S.M.

I. El Naqa, S.M. Lehnert, et al Modeling of radiotherapy induced damage in locally advanced lung cancer by a novel system radiobiology approach Canadian Institutes of Health Research (CIHR) (2011-2016) ................................................................................................................................................ $135,790

LEVESQUE, I.R.

I.R. Levesque (PI) Start-up grant: Methods in magnetic resonance imaging Montreal General Hospital Foundation, Research Institute-McGill University Health Centre (MGH, RI-MUHC) (2013-2016) ................................................................................................................................................... $75,000 PARKER, W.

J. Seuntjens, C.R. Freeman, W. Parker, G. Shenouda Monte Carlo-based mixed electron/photon beam inverse treatment planning, delivery and verification Canadian Institutes for Health Research (CIHR) (2010-2015) ................................................................................................................................................... $60,000

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PIKE, G.B.

G.B. Pike et al. Quantitative magnetic resonance imaging of multiple sclerosis Canadian Institutes of Health Research (CIHR), operating grant (2010-2015) ................................................................................................................................................. $201,310 R. Zatorre, V. Penhume (PIs), A. Evans, K. Hyde, G.B. Pike Brain anatomy in auditory and motor learning: Predispositions & plasticity Canadian Institutes of Health Research (CIHR), operating grant (2010-2015) ................................................................................................................................................. $152,290 T. Paus, G.B. Pike, D. Gaudet Programming brains across generations: How early environment and genes shape the risk of addiction Canadian Institutes of Health Research (CIHR), team grant (Canada-Finland) (2011-2014) ................................................................................................................................................. $333,333 V. Gracco, G.B. Pike et al. Regroupement pour la recherche sur le cerveau, le langage et la musique FQRNT and FQRSC (2011-2017) ................................................................................................................................................. $375,000 K. Siddiqi, D.L. Collins, G.B. Pike Reconstruction angulaire et radiale dan l’IRM de diffusion (Radian and angular reconstruction in diffusion MRI) FQRNT, team grant (2011-2014) ................................................................................................................................................... $42,000 K. Hyde, G.B. Pike, E. Fombonne Auditory processing in typical development and in autism spectrum disorder: Insight from the brain and behavior Canadian Institutes of Health Research (CIHR), operating grant (2011-2016) ................................................................................................................................................. $114,109 G.B. Pike (McGill) (PI), J. Near (Oxford) Undersampled two-dimensional magnetic resonance spectroscopy for accurate quantification of tissue metabolites in-vivo Oxford-McGill Neuroscience Collaboration Funding (OMNC) (2011-2014) ................................................................................................................................................... $10,800 G.B. Pike et al. Functional MRI of brain physiology Canadian Institutes of Health Research (CIHR), operating grant (2012-2017) ................................................................................................................................................. $206,359 G.B. Pike et al. MRI acquisition and analysis methods for image guided neurosurgery Natural Sciences & Engineering Research Council (NSERC), discovery grant (2012-2017) ................................................................................................................................................... $52,000 G.B. Pike et al. CREATE program in medical image analysis Natural Sciences & Engineering Research Council – Collaborative Research & Training Experience (NSERC-CREATE), CREATE grant (2012-2018) ................................................................................................................................................. $275,000

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J. Seuntjens, G.B. Pike et al. Medical Physics Research Training Network (MPRTN) Natural Sciences & Engineering Research Council – Collaborative Research & Training Experience (NSERC-CREATE), CREATE grant (2013-2019) ................................................................................................................................................. $333,333 G.B. Pike et al. Electrical and metabolic analysis of human epileptogenic lesions Canadian Institutes of Health Research (CIHR), operating grant (2013-2018) ................................................................................................................................................. $161,000 G.B Pike Health brain aging Campus Alberta Innovates Chair, grant (2013-2020) ................................................................................................................................................. $642,857

READER, A. (total grant amount) A.J. Reader Canada Research Chair in Positron Emission Tomography Canada Research Chairs Program (2008-2013) ................................................................................................................................................. $100,000 A.J. Reader Scanner-adaptive image reconstruction platform for accelerated technology transfer in Positron emission tomography Centre of Excellence in Commercialization & Research (CECR) (2010-2013) ................................................................................................................................................... $33,333 A.J. Reader Task-oriented optimization of high- performance positron emission tomography Natural Sciences & Engineering Research Council (NSERC) (2010-2015) ................................................................................................................................................... $27,000 A.J. Reader Infrastructure operating grant McGill University (2012-2013) ................................................................................................................................................... $24,000 A.J. Reader Canada Research Chair in Positron Emission Tomography Canada Research Chairs Program (renewal) (2013-2018) ................................................................................................................................................. $100,000 J. Seuntjens, A.J. Reader et al. Medical Physics Research Training Network (MPRTN) Natural Sciences & Engineering Research Council – Collaborative Research & Training Experience (NSERC-CREATE), CREATE grant (2013-2019) ................................................................................................................................................. $333,333

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SEUNTJENS, J.

J. Seuntjens et al. Accurate reference dosimetry of non-standard beams using water calorimetry, ionization chambers and Monte Carlo dose calculations Natural Sciences & Engineering Research Council (NSERC), discovery grant (2014-2019) ................................................................................................................................................... $52,000 J. Seuntjens et al. Monte Carlo-based mixed electron/photon beam inverse treatment planning, delivery & verification Canadian Institutes for Health Research (CIHR), operating grant (2010-2015) ................................................................................................................................................... $60,000 J. Seuntjens “Bourse” for students in medical physics Ministère de la santé et des services sociaux du Québec (2012-2014) ................................................................................................................................................... $17,000 J. Seuntjens “Bourse” for students in medical physics Ministère de la santé et des services sociaux du Québec (2013-2015) ................................................................................................................................................... $17,000 J. Seuntjens et al. Medical Physics Research Training Network (MPRTN) Natural Sciences & Engineering Research Council – Collaborative Research & Training Experience (NSERC-CREATE), CREATE grant (2013-2019) ................................................................................................................................................. $333,333 J. Seuntjens Monte Carlo techniques in the optimization of radiation therapy delivery and outcomes (Canadian Institutes of Health Research, Foundation scheme grant; PI) (2015-2022) .................................................................................................................................................... $85.242 J. Seuntjens, J. Nadeau et al Nanoparticles for enhancement of radiotherapy with fewer side effects (Canadian Institutes of Health Research, Operating; PI, adopted from J. Nadeau) (2014-2017) .................................................................................................................................................... $98,680 J. Seuntjens, I El Naqa et al Hybrid image analysis for Radiotherapy (Canadian Institutes of Health Research, Operating; PI, adopted from I El Naqa) (2014-2018) .................................................................................................................................................... $98,680 J. Seuntjens, I El Naqa et al Modelling of Radiotherapy Induced Damage in Locally Advanced Lung Cancer by (etc) (Canadian Institutes of Health Research, Operating; PI, adopted from I El Naqa) (2011-2016) .................................................................................................................................................. $135,790

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SYME, A.

A. Syme (co-applicant) et al. VIRA – Virtual Isocenter RapidArc Varian, research grant (2013-20145 .................................................................................................................................................. $25,000 A. Syme (co-applicant) et al. Exploration of organic electronics as radiation detectors Natural Sciences & Engineering Research Council (NSERC), research grant (2013-2015) ................................................................................................................................................... $27,000

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APPENDIX XIV.

RESEARCH INTERESTS OF THE ACADEMIC MEMBERS OF THE MPU ASIEV, Krum Quality control of Varian linear accelerator, Theratron T780 cobalt unit,

Gulmay orthovoltage machine, Nucletron MicroSelectron HDR brachytherapy afterloader.

COLLINS, Louis Image processing, registration, segmentation, MRI, image guided

neurosurgery, multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, epilepsy.

CONNELL, Tanner Modulated electron therapy; MV imaging with low-Z targets. DAVIS, Stephen Accurate radiation dosimetry applied to calibration of radiation

measurement devices. Commissioning of a Monte Carlo treatment planning system.

DEBLOIS, François Photon and electron beam dosimetry, stereotactic radiosurgery, Monte

Carlo treatment planning and medical physics software. DEVIC, Slobodan Radiochromic film dosimetry; biological target volumes for radiotherapy

treatment planning. EL NAQA, Issam Oncology bioinformatics, computational and systems biology,

multimodality imaging, adaptive radiotherapy. ENGER, Shirin Monte Carlo-based dose planning systems, radiation dosimetry,

brachytherapy, detector development, radiation protection. EVANS, Michael D.C. Clinical aspects of radiotherapy, including low and high dose rate

brachytherapy, dynamic external beam radiotherapy, linear accelerator calibration and quality assurance, computerized treatment planning, radiation safety.

FURSTOSS, Christophe Clinical and research projects, Canadian Partnership for quality

radiotherapy, new treatment techniques (IGRT, SRT, SBRT). GAUVIN, Alain Interest in imaging informatics revolves mostly around two topics:

regional imaging integration, and multi-system integration of medical imaging within the hospital IT ecosystem.

HEGYI, Gyorgy Image analysis and manipulation, patient radiation dose determination in

radiology with special dosimetry techniques, health physics. Different diagnostic imaging procedures can result in significant radiation dose to the patient. The radiation dose to pediatric patients during CT procedures is of special concern. Special dosimmetry tools are required for routine CT dose measurements like radiochromic films, MOSFETs others.

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HOBSON, Maritza Development of “in vivo” transit dosimetry procedures for EPIDs;

characterization of portal imagers; development of routine QA procedures for quality on OBIs; CT Sim using ACR CT phantom.

KILDEA, John Electronic QA; database tools, neutron spectra. LEGÉR, Pierre Distance and position sensing, dose detection, dose delivery, x-ray

control, general application of electronic to geophysics and radiotherapy. LEHNERT, Shirley M. Radiobiology, tumor biology, drug delivery, functional imaging. LEVESQUE, Ives Quantitative MRI techniques, signal modeling, pulse sequence

development, (Siemens, GE), image analysis, applications to multiple sclerosis.

LIANG, Li Heng Ortho-voltage treatment machine, film dosimetry. MOFTAH, Belal Developing of 3D poymer gel dosimeter for advanced radiotherapy

treatment planning and verification systems. PARKER, William Pediatric radiotherapy, quality assurance and dosimetric measurements

of IMRT beams. PATROCINIO, Horacio J. Stereotactic radiosurgery, image-guided stereotactic body radiation

therapy, motion and margin assessment in radiotherapy, image-guided brachytherapy.

PIKE, G. Bruce Medical imaging, magnetic resonance imaging, functional brain imaging,

brain physiology, image guided neurosurgery. PODGORSAK, Ervin B. Photon and electron beam dosimetry, stereotactic radiosurgery, general

applications of physics to radiotherapy. POON, Emily Monte Carlo dose calculations; adaptive radiotherapy; treatment

planning software development; brachytherapy dosimetry; deformable image registration.

POPOVIC, Marija Treatment of head & neck Ewing’s sarcoma in pediatric & young adult

patients; treatment plan comparison for larynx, oro- and hypopharynx carcinomas: RapidArc vs sliding-window IMRT techniques.

READER, Andrew Image reconstruction, 4D Positron Emission Tomography (PET). RICHARDSON, Richard B. Radiation, p53, stem cells, cancer, aging. RUO, Russell Intensity modulated radiotherapy (IMRT), image guided radiotherapy

(IMGT), stereotactic radiosurgery (SRS). SARFEHNIA, Arman Water calorimetry, particle therapy dosimetry, detector design and

optimization, beam quality, absolute dosimetry. SERBAN, Monica Commissioning and validation of Eclipse electron Monte Carlo treatment

planning system.

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SEUNTJENS, Jan Radiation dosimetry; Monte Carlo simulation, radiation detectors, device

development, radiation biophysics and clinical applications. SOISSON, Emilie Stereotactic, tomotherapy, Monte Carlo, image guidance (IGRT). STROIAN, Gabriela Deformable registration, heterogeneity corrections, Monte simulations,

image guided radiotherapy, radiobiological modeling in brachytherapy. SYME, Alasdair Virtual Isocentre RapidArc (VIRA), novel radiation detectors, plastic

scintillation detectors. THEBAUT, Jonathan Monte Carlo, orthovoltage/superficial, IMRT/VMAT. TOMIC, Nada Image guided radiation therapy; radiochromic film dosimetry. YBARRA, Norma Study of biomarker expression in solid tumors treated with radiotherapy

to better predict tumor response; patient susceptibility to radiotherapy; alternative therapies to reduce toxicity of irradiation.

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APPENDIX XV.

MPU SEMINAR SERIES : 2015 CALENDAR YEAR

Winter 2014-2015

January 23 : Stephen Kry (M.D. Anderson Cancer Centre, Houston, TX)

Neutrons in radiation oncology: Measurement and implications January 30 : Alex Vitkin (University of Toronto, Toronto, ON)

Photon mayhem: Using light for structural and functional assessment of biological tissues February 27 : Jean-Yves Fiset (Canadian Nuclear Safety Commission, Ottawa, ON)

Improving human performance: Myths, truths, and a few useful tips March 13 : Arman Sarfehnia (Sunnybrook Health Sciences Ctr, Toronto, ON)

MRI – linac: Benefits & challenges March 20 : Stephen Breen (Princess Margaret Cancer Ctr, Toronto, ON)

Applications of statistical process control in radiation medicine March 27 : Marc-André Fortin (Université Laval, Laval, QC)

Gold-based radioactive nanoparticles for applications in brachytherapy April 10 : Shirin Enger (McGill University Health Centre, Montreal, QC)

Rotating shield brachytherapy, detector development, micro/macro dosimetry, and everything inbetween

June 12 : Paolo Russo (University of Naples, Naples, Italy)

Cone beam breast CT with dedicated scanners June 26 : Lars Lindvold (Technical University of Denmark, Lyngby, Denmark) Fiber optical coupled organic polymer scintillators

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Fall 2015-2016 August 28: Ivan Buzurovic (Medical Physics/Biophysics, Harvard Medical School, Boston, MA) Innovative brachytherapy September 11: Ryan Flynn (Medical Physics, U Iowa, Iowa City, IA) Rotating shield brachytherapy for prostate and cervical cancer September 18: Avishek Chatterjee (Nuclear Physics, U Geneva, Geneva, Switzerland) Searching for new physics using the ATLAS detector at the large hadron collider September 24-25: Various speakers MPRTN-NSERC CREATE Workshop, RI-MUHC October 09 : Richard Richardson (Canadian Nuclear Laboratories, Deep River, ON) Are ionizing radiation effects more mitochondria-centric than nucleus-centric? October 16 : Andrea Armstrong (Radioisotope Development, McMaster U, Hamilton, ON) T1 Mapping: The Up & Down (& Up) Story of an Old Technique October 23 : Ernesto Mainegra-Hing (Ionizing Radiation Standards, NRCC , Ottawa, ON) Comparison between EGSnrc, GEANT4, MCNP and Penelope for photon beams November 06 : Omar Chebli (Kirontech, Helsinki, Finland) Applications of machine learning in healthcare data November 09 : B. Gino Fallone (Medical Physics, Cross Cancer Institute, Edmonton, AB) Integrated MRI – Linear accelerator November 13 : Francisco Nunez (Philips Radiation Oncology Systems, Madison, WI) Proton treatments in radiotherapy November 20 : Gassan Massarweh (McConnell Brain Imaging Ctr, MNI, Montréal, QC) Cyclotron and radiochemistry at the McConnell Brain Imaging Centre today and tomorrow November 27 : Farrah Flegal (Biodosimetry, Canadian Nuclear Laboratories, Deep River, ON) Canadian emergency biodosimetry dose response network Deember 08 : Christopher Johnstone (Physics & Anatomy, U Victoria, Victoria, BC) Automated microCT image analysis for small animal image-guided radiotherapy December 08 : Magdalena Bazalova-Carter (Physics & Anatomy, U Victoria, Victoria, BC) From x-ray fluorescence CT imaging to dose-enhanced radiation therapy

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Medical Physics Unit Appendix XVI. Annual Report 2015

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APPENDIX XVI.

COMMITTEE INVOLVEMENT of MPU FACULTY MEMBERS

within McGill from January-December 2015 COLLINS, L.: Chair, Brain Imaging Centre Computing Infrastructure Committee (2004-present) Chair, Graduate Program, Dept Biomedical Engineering Member, Dept Biomedical Engineering Graduate Committee (2005-present) Member, Graduate Program in NeuroScience Committee (2000-present) Chair, Graduate Program in NeuroScience Admissions Committee (2008-present) Member, Killam Lecture Series Committee (1999-present) Member, MNI Named Lecture Committee (2002-present) Member, Internal Grant Review Committee Montreal Neurological Institute DEBLOIS, F.: Member, Medical Physics Residency Committee (2008-present) McGill University Member, Radiation Oncology Radiation Safety Committee (2008-present) Member, Radiation Oncology Quality Assurance Committee (2008-present) SMBD Jewish General Hospital ENGER, S.: Member, Medical Physics Unit Seminar Committee (2015-present) Member, Medical Physics Unit Curriculum Committee (2015-present) Member, Medical Physics Unit Admissions Committee (2015-present) McGill University Member, Medical Physics Radiation Safety Committee Member, MUHC Brachytherapy Group McGill University Health Centre EVANS, M.D.C.: Member, Residency Training Committee (1999-present) Member, Radiation Safety Committee Medical Physics Unit, McGill University Member, Radiation Safety Committee (2003-present) Member, Medical Physics Radiation Safety Committee (2006-present) Member, Radiation Oncology QA Committee (2002-present) Member, Medical Physics QA Committee (2006-present) McGill University Health Centre HEGYI, G.: Member, Radiation Safety Committee McGill University Health Centre (MUHC) KILDEA, J.: Member, Medical Physics QA Committee Member, Medical Physics Radiation Safety Committee Member, Radiation Oncology Electronic Chart Committee Member, Radiation Oncology LEAN Healthcare Committee McGill University Health Centre Chair, Seminar Committee (2013-present) Member, Graduate Committee (2013-present) Member, Curriculum Committee (2011-present) Member, Alumni Committee (2013-present)

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LEHNERT, S.M.: Member, Radiation Safety Committee Member, Radiation Oncology Residents Training Committee McGill University Health Centre PARKER, W.A.: Director, Residency Training Committee (Radiation Oncology Physics) Member, Quality Assurance Committee Member, Radiation Safety Committee Medical Physics, McGill University Health Centre President, Board of Directors, MGH Child Care Centre Clinical Advisor, Glen Campus Cancer Centre Member, Radiation Therapy Equipment Procurement Committee Member, Access to Treatment Committee (Radiation Oncology) Member, Event Reporting Committee Member, Pre-treatment Image Verification Committee Member, Review of Patient Waiting Times - Quality Assurance Committee

(Radiation Oncology) McGill University Health Centre Member, CARMS – Radiation Oncology Resident Selection Committee McGill University PATROCINIO, H.J.: Member, Seminar Committee Clinical Coordinator, Residency Training Program (Radiation Oncology Physics) Member, Residency Training Committee (Radiation Oncology Physics) Member, Medical Physics Quality Assurance Committee Member, Radiation Safety Committee Medical Physics, McGill University Member, Radiation Oncology Brachytherapy Committee Member, Novalis / SRS Committee McGill University Health Centre PIKE, G.B.: Co-Chair, Ad-hoc Committee: Coordination of BME Activities at McGill (2009-present) Member, Departmental Tenure Committee (2005-present) Member, Departmental Advisory Committee (2010-present) Member, Ad-hoc Advisory Committee for Merit Exercises (2011-present) Biomedical Engineering Department, McGill University Member, Admissions Committee (2008-present) Member, Search Committee – Academic Positions (2009-present) Medical Physics Unit, McGill University Director, McConnell Brain Imaging Centre (1999-present) Chair, Magnetic Resonance Research Committee (1997-present) Member, PET Working Committee (1999-present) Chair, BIC Business Committee (1999-present) Member, McBIR Faculty Search Committee (2002-present) Member, Small Animal MRI Committee (2007-present) Member, Centres of Excellence for Commercialization & Research Committee (CECR) (2007-present) Special Advisor – Interim Director of the MNI (2011-present) Member, MNI Strategic Committee (2009-present)

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Member, CECR Advisory Committee (2010-present) Member, Research Advisory Committee (2011-present) Member, Search Committee for the Director/MNI and Associate Director General/MNH (2011-present) Montreal Neurological Institute Member, Faculty Search Committee (2011-present) Douglas Research Institute READER, A.: Member, PET Working Committee (2008-present) Montreal Neurological Institute (MNI) SEUNTJENS, J.: Chair, Graduate Admissions Committee (2009-present) Chair, Curriculum Committee (2011-present) Chair, Alumni Committee (2013-present) Medical Physics Unit, McGill University Member, Oncology Management Committee (2009-present) Member, University Tenure Committee (Dept. Religious Studies, 2012-present) Director, Medical Physics Research Training Network (2013-present) Co-Director, Residency Training Committee (Radiation Oncology Physics) SOISSON, E.: Member, Grant Review Committee – Studentship & Fellowship Awards Research Institute, McGill University Health Centre Member, IGRT Committee, Radiation Oncology Department Member, Dosimetry Committee, Radiation Oncology Department Member, Machine Quality Assurance Committee McGill University Health Centre Member, Alumni Committee (2013-present) Medical Physics Unit, McGill University

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Medical Physics Unit Appendix XVII. Annual Report 2015

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APPENDIX XVII.

COMMITTEE INVOLVEMENT of MPU STAFF MEMBERS

OUTSIDE McGILL from January-December 2015 COLLINS, D.L.: Member, Editorial Board, Journals: Medical Image Analysis, NeuroImage, Medical Physics, Human Brain Mapping, IEEE Transactions on Medical Imaging Member, Review Board, CIHR, NSERC, FRSQ, MSSC, Burroughs Wellcome Foundation DEBLOIS, F.: President, (2011-present) Member, Science & Education Committee; Professional Affairs Committee; Quality Assurance & Radiation Safety Committee (2010-present) Association Québecoise des Physicien(ne)s Médicaux Cliniques (AQPMC) DEVIC, S.: Track Co-Chair, Biophysics & Modeling, World Congress on Medical Physics & Biomedical Engineering (IUPESM), Toronto, ON (June 2015) Member, Pediatric Normal Tissue Effects in the Clinic (PENTEC) (2013-present) Member, Working Group on Biological Effects of Hypofractionated Radiotherapy Stereotactic Body Radiation Therapy (2011-present) Member, AAPM Task Group No. 211 – Classification, Advantages & Limitations of the

Autosegmentation Approaches for PET (2011-present) Member, Editorial Board American Journal of Science & Engineering (2011-present) Member, Editorial Board Journal of Computational & Mathematical Methods in Medicine (2014-present) Journal of ISRN Radiology (2012-present) Journal of Radiation Oncology, Biology & Physics (2009-present) Journal of Medical Physics (2009-present) Journal of Radiation Oncology Informatics (2009-present) EVANS, M.D.C.: Member, Membership Oral Exam Committee Canadian Medical Association (CMA) Member, TG113 Clinical Trials Working Group American Association of Physicists in Medicine (AAPM) Member, Quality Assurance & Radioprotection Committee Association Québecoise des Physicien(ne)s Médicaux Cliniques (AQPMC) Member, QARSAC Liaison Committee with CNSC Canadian Organization of Medical Physicists (COMP) Member, Advanced Practice Oral Examiners Committee Canadian Association of Medical Radiation Technologists (CAMRT) FURSTOSS, C.: Member, Canadian Partnership for Quality Radiotherapy (CPQR)

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LEHNERT, S.M.: Member, Scientific Advisory Committee (2001-present) Biological Research Facility, AECL Laboratories, Chalk River Member, Scientific Advisory Board (2005-present) Resonant Medical Systems, Montreal, Quebec Member, Editorial Advisory Board Open Nuclear Medicine Journal Member, Editorial Board International Journal of Cancer Research & Remedies PARKER, W.A.: Chairman, Summer School Sub-Committee Member, Continuing Professional Development Committee Chairman, RSNA Education Coordination Sub-Committee American Association of Physicists in Medicine (AAPM) Oral Examiner, Membership Exam Canadian College of Physicists in Medicine (CCPM) Member, Comité de devis techniques en radiothérapie Association Québecoise des Physiciens Médicaux Cliniques (AQPMC) Member, Credential Review Committee Canadian College of Physicists in Medicine (CCPM) PATROCINIO, H.J.: Oral examiner, Fellowship & Membership exams Canadian College of Physicists in Medicine (CCPM) Member, Professional Affairs Committee Canadian Organization of Medical Physicists (COMP) ABR Item Writer, Radiological Physics exam American Board of Radiology PIKE, G.B.: Ad-hoc reviewer & Panel Member, Multiple Granting Agencies Member, Editorial Board Journal - NeuroImage Member, Advisory Board / Committee CInAPCe (Neuroscience) Project, Sao Paolo, Brazil Quantitative Neuroscience with Magnetic Resonance (QNMR), Yale University Quebec Bio-Imaging Network (QBIN) National Research Council of Canada, Institute for Biodiagnostics Ontario Institute for Cancer Research (Chair, January 2013) READER, Andrew: Reviewer, Grant applications Research Grants Council, Hong Kong Wellcome Trust, England Associate Editor, International Journal of Tomography & Statistics Member, IEEE Nuclear & Medical Imaging Sciences Council (2011-present) Member, Scientific Committee, Fully 3D Reconstruction Meeting (2011) SEUNTJENS, J.: Key Mentor (national), Excellence in Radiation Research in the 21st Century Training Program (STARS21) Canadian Institutes for Health Research (2006-present) Chair, Committee on Small-field Photon Dosimetry & Applications in Radiotherapy (2010-present) International Commission on Radiation Units & Measurements (ICRU) Member, Medical Physics & Imaging grant panel (2009-present) Canadian Institutes for Health Research (CIHR)

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Chair, Workgroup on the Development of a Calibration Protocol for TG-51 Non-compliant Beams (2007-present) American Association of Physicists in Medicine (AAPM) Member, International Advisory Committee on Small-field Dosimetry International Atomic Energy Agency (IAEA) (2007-present) Member, Workgroup on Update of TG-51 (WGTG51) (2006-2013) American Association of Physicists in Medicine (AAPM) Member, International Advisory Committee on IAEA Phase Space International Atomic Energy Agency (IAEA) (2006-present) SOISSON, E.: Board Member, Medical Dosimetrists Certification Board (MDCB) (2014) Canadian Organization of Medical Physics (COMP) (2014)