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TABEL EVIDENCE MATRIX FOR LITERATUR LJ METHODOLOGICAL CHARACTERISTICS CONTENT SPESIFIC FINDING Year Study Design Studi Population Sampel Size Results Conclusion 1 2013 MODEL “PELATIHAN PEDULI DUKUN BAYI” UNTUK MENINGKATKAN POTENSI SEBAGAI AGENT OF CHANGE PELAKSANAAN INISIASI MENYUSU DINI Lead Author, Article Title, Jurnal Citation Intervention Characteristic Pfeiffer dan Mwaipopo, Menyampaikan di rumah atau di fasilitas kesehatan? perilaku mencari kesehatan perempuan dan peran dukun bayi di Tanzania, BMC Kehamilan dan Persalinan 2013, 13:55 http://www.biomedc entral.com/1471- 2393/13/55 Menggunakan pendekatan campuran metode, kuantitatif maupun kualitatif Penelitian ini difokuskan pada berbagai tingkatan dalam masyarakat dan sistem kesehatan, yang melibatkan (1) wanita yang telah disampaikan dalam 2 bulan terakhir, (2) dukun bayi, dan (3) anggota masyarakat 200 wanita diwawancarai: 100 dari mereka di perkotaan dan 100 di pedesaan. 14 dukun beranak (10 di Kabupaten Masasi dan 4 di Ward Ilala, Dar es Salaam), perspektif masyarakat, 8 Focus Group Diskusi (4 di Ward Ilala dan 4 di Maundo) N / A bukan intervensi Hasil dari perkotaan menunjukkan bahwa prestasi yang signifikan telah dibuat dalam hal mempromosikan kehamilan dan jasa pengiriman terkait melalui tenaga kesehatan terampil. Wanita hamil memiliki tingkat kesadaran yang tinggi dan jelas lebih memilih untuk memberikan di fasilitas kesehatan. Skenario berbeda di pedesaan (Masasi District), di mana tenaga kesehatan terlatih dan fasilitas kesehatan yang lengkap belum nyata, sehingga melahirkani di rumah dengan bantuan baik TBA atau saudara. Alih-alih berfokus pada sektor tradisional, ia berpendapat bahwa perhatian lebih harus dibayar untuk (1) meningkatkan akses serta penguatan sistem kesehatan untuk menjamin persalinan oleh tenaga kesehatan terlatih; dan (2) menjembatani kesenjangan antara masyarakat dan sektor kesehatan formal melalui konseling berbasis masyarakat dan pendidikan kesehatan, yang disediakan oleh petugas kesehatan desa terlatih dan diawasi yang menginformasikan warga tentang pelayanan kesehatan promotif dan preventif, termasuk kesehatan ibu dan bayi.

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1 & 2TABEL EVIDENCE MATRIX FOR LITERATUR MODEL PELATIHAN PEDULI DUKUN BAYI UNTUK MENINGKATKAN POTENSI SEBAGAI AGENT OF CHANGE PELAKSANAAN INISIASI MENYUSU DINI

LJLead Author, Article Title, Jurnal CitationMETHODOLOGICAL CHARACTERISTICSCONTENT SPESIFIC FINDINGYear Study DesignStudi PopulationSampel SizeIntervention CharacteristicResultsConclusionOther Comments1Pfeiffer dan Mwaipopo, Menyampaikan di rumah atau di fasilitas kesehatan? perilaku mencari kesehatan perempuan dan peran dukun bayi di Tanzania, BMC Kehamilan dan Persalinan 2013, 13:55 http://www.biomedcentral.com/1471-2393/13/552013Menggunakan pendekatan campuran metode, kuantitatif maupun kualitatifPenelitian ini difokuskan pada berbagai tingkatan dalam masyarakat dan sistem kesehatan, yang melibatkan (1) wanita yang telah disampaikan dalam 2 bulan terakhir, (2) dukun bayi, dan (3) anggota masyarakat200 wanita diwawancarai: 100 dari mereka di perkotaan dan 100 di pedesaan. 14 dukun beranak (10 di Kabupaten Masasi dan 4 di Ward Ilala, Dar es Salaam), perspektif masyarakat, 8 Focus Group Diskusi (4 di Ward Ilala dan 4 di Maundo)N / A bukan intervensiHasil dari perkotaan menunjukkan bahwa prestasi yang signifikan telah dibuat dalam hal mempromosikan kehamilan dan jasa pengiriman terkait melalui tenaga kesehatan terampil. Wanita hamil memiliki tingkat kesadaran yang tinggi dan jelas lebih memilih untuk memberikan di fasilitas kesehatan. Skenario berbeda di pedesaan (Masasi District), di mana tenaga kesehatan terlatih dan fasilitas kesehatan yang lengkap belum nyata, sehingga melahirkani di rumah dengan bantuan baik TBA atau saudara.Alih-alih berfokus pada sektor tradisional, ia berpendapat bahwa perhatian lebih harus dibayar untuk (1) meningkatkan akses serta penguatan sistem kesehatan untuk menjamin persalinan oleh tenaga kesehatan terlatih; dan (2) menjembatani kesenjangan antara masyarakat dan sektor kesehatan formal melalui konseling berbasis masyarakat dan pendidikan kesehatan, yang disediakan oleh petugas kesehatan desa terlatih dan diawasi yang menginformasikan warga tentang pelayanan kesehatan promotif dan preventif, termasuk kesehatan ibu dan bayi.Beberapa penelitian formatif yang bertujuan mengevaluasi efektivitas dan biaya strategi scalable sedang dilaksanakan dalam rangka meningkatkan kesehatan neonatal dan maternal di pedesaan Tanzania selatan melalui intervensi berbasis masyarakat dan dengan memperkenalkan tenaga kesehatan masyarakat2"Christopher J Gill, et. Al" "Pengaruh pelatihan dukun bayi angka kematian bayi baru lahir (Lufwanyama Neonatal Survival Project):acak terkontrol "" BMJ 2011; 342: d346doi: 10.1136/bmj.d346 "2010Prospektif, klaster acak dan terkontrol studi efektivitas.Semua kelahiran yang terjadi di rumah ibu, di daerah pedesaan.127 dukun bayi dan ibu dan bayi mereka (3559 bayi yang dilahirkan tanpa memandang status vital)Menggunakan desain unblinded, dukun bayi secara acak untuk kelompok intervensi atau kelompok kontrol. Intervensi memiliki dua komponen: pelatihan dalam versi modifikasi dari protokol resusitasi neonatal, dan amoksisilin dosis tunggal ditambah dengan rujukan yang difasilitasi bayi ke pusat kesehatan. Kontrol bidan melanjutkan standar yang sudah ada perawatan (keterampilan kebidanan dasar dan penggunaan kit persalinan bersih)."Di antara 3497 pengiriman dengan informasi yang dapat dipercaya, angka kematian pada hari ke 28 setelah kelahiran adalah 45% lebih rendah di antara bayi lahir hidup disampaikan oleh intervensi bidan daripada bidan control (rasio tingkat 0,55, 95% interval kepercayaan 0,33-0,90). Penurunan terbesarangka kematian berada di 24 jam pertama setelah lahir: 7,8 kematian per 1.000 kelahiran hidup untuk bayi disampaikan oleh intervensi bidan dibandingkan dengan 19,9 per 1000 untuk bayi yang dilahirkan oleh kontrol bidan (0,40, 0,19-0,83). Kematian akibat asfiksia lahir yangdikurangi dengan 63% di antara bayi yang dilahirkan oleh intervensi bidan (0,37, 0,17-0,81) dan sebesar 81% dalam dua hari pertama setelah lahir (0,19, 0,07-0,52). Lahir mati dan kematian akibat infeksi serius terjadi pada tingkat yang sama pada kedua kelompok."Pelatihan dukun bayi untuk mengelola kondisi perinatal umum secara signifikan mengurangi kematian neonatal di pedesaan Afrika.Pendekatan ini memiliki potensi yang tinggi untuk diterapkan untuk pengaturan yang sama dengan populasi di pedesaan terpencil.

Sheet2TABEL EVIDENCE MATRIX FOR LITERATUR MODEL PELATIHAN PEDULI DUKUN BAYI UNTUK MENINGKATKAN POTENSI SEBAGAI AGENT OF CHANGE PELAKSANAAN INISIASI MENYUSU DINI

NOLead Author, Article Title, Jurnal CitationMETHODOLOGICAL CHARACTERISTICSCONTENT SPESIFIC FINDINGYear Study DesignStudi PopulationSampel SizeIntervention CharacteristicResultsConclusionOther Comments1Pfeiffer and Mwaipopo, Delivering at home or in a health facility? health-seeking behaviour of women and the role of traditional birth attendants in Tanzania, BMC Pregnancy and Childbirth 2013, 13:55 http://www.biomedcentral.com/1471-2393/13/552013Using a mixed-methods approach, quantitative as well as qualitativeThe study focused on various levels within the society and the health system, involving (1) women who had delivered in the past 2 months, (2) TBAs, and (3) community members200 women were interviewed: 100 of them in urban and 100 in rural sites. 14 TBAs (10 in Masasi District and 4 in Ward Ilala, Dar es Salaam), the community perspective, 8 Focus-Group Discussions (4 in Ward Ilala and 4 in Maundo)N/A not an interventionThe results from the urban site show that significant achievements have been made in terms of promoting pregnancy- and delivery-related services through skilled health workers. Pregnant women have a high level of awareness and clearly prefer to deliver at a health facility. The scenario is different in the rural site (Masasi District), where an adequately trained health workforce and well-equipped health facilities are not yet a reality, resulting in home deliveries with the assistance of either a TBA or a relative.Instead of focusing on the traditional sector, it is argued that more attention should be paid towards (1) improving access to as well as strengthening the health system to guarantee delivery by skilled health personnel; and (2) bridging the gaps between communities and the formal health sector through communitybased counselling and health education, which is provided by well-trained and supervised village health workers who inform villagers about promotive and preventive health services, including maternal and neonatal health.Several formative research studies that aim at evaluating the effectiveness and cost of scaleable strategies are being implemented in order to improve neonatal and maternal health in rural southern Tanzania through community-based interventions and by introducing community health workers2Christopher J Gill, et. Al "Effect of training traditional birth attendants on neonatalmortality (Lufwanyama Neonatal Survival Project):randomised controlled study" BMJ 2011; 342:d346doi:10.1136/bmj.d3462010Prospective, cluster randomised and controlled effectiveness study.All births carried out by study birth attendants occurred at mothers homes, in rural village settings.127 traditional birth attendants and mothers and their newborns (3559 infants delivered regardless of vital status)Using an unblinded design, birth attendants were cluster randomised to intervention or control groups. The intervention had two components: training in a modified version of the neonatal resuscitation protocol, and single dose amoxicillin coupled with facilitated referral of infants to a health centre. Control birth attendants continued their existing standard of care (basic obstetric skills and use of clean delivery kits).Among 3497 deliveries with reliable information, mortality at day 28 after birth was 45% lower among liveborn infants delivered by intervention birth attendants than control birth attendants (rate ratio 0.55, 95% confidence interval 0.33 to 0.90). The greatest reductionsin mortality were in the first 24 hours after birth: 7.8 deaths per 1000 live births for infants delivered by intervention birth attendants compared with 19.9 per 1000 for infants delivered by control birth attendants (0.40, 0.19 to 0.83). Deaths due to birth asphyxia werereduced by 63% among infants delivered by intervention birth attendants (0.37, 0.17 to 0.81) and by 81% within the first two days after birth (0.19, 0.07 to 0.52). Stillbirths and deaths from serious infection occurred at similar rates in both groups.Training traditional birth attendants to manage common perinatal conditions significantly reduced neonatal mortality in a rural African setting. This approach has high potential to be applied to similar settings with dispersed rural populations.3Ebuehi and Akintujoye, Perception and utilization of traditional birth attendants by pregnant women attending primary health care clinics in a rural Local Government Area in Ogun State, Nigeria. Dove Press Journals; International Journal of Womens Health 3 Februari 20122012A quantitative design ; a descriptive cross-sectional studyThe study was carried out among registered pregnant women attending the antenatal clinics of selected PHCs inIfo LGA.250 pregnant women attending four randomly selected primary health care clinics in the LGA..N/A not an interventionAlmost half (48.8%) of the respondents were in the age group 2635 years, with a mean age of 29.4 kurang lebih7.33 years. About two-thirds (65.6%) of the respondents had been pregnant 24 times before. TBA functions, as identified by respondents, were: taking normal delivery (56.7%), providing antenatal services (16.5%), performing caesarean section (13.0%), providing family planning services (8.2%), and performing gynaecological surgeries (5.6%). About 6/10 (61.0%) respondents believed that TBAs have adequate knowledge and skills to care for them, however, approximately 7/10 (69.7%) respondents acknowledged that complications could arise from TBA care. Services obtained from TBAs were: routine antenatal care (81.1%), normal delivery (36.1%), special maternal bath to ward off evil spirits (1.9%), concoctions for mothers to drink to make baby strong (15.1%), and family planning services (1.9%). Reasons for using TBA services were: TBA services are cheaper (50.9%), TBA services are more culturally acceptable in my environment (34.0%), TBA services are closer to my house than hospital services (13.2%), TBAs provide more compassionate care than orthodox health workers (43.4%), and TBA service is the only maternity service that I know (1.9%). Approximately 8/10 (79.2%) of the users (past or current) opined that TBA services are effective but could be improved with some form of training (78.3%). More than three-quarters (77.1%) opposed the banning of TBA services. Almost 7/10 (74.8%) users were satisfied with TBA services.Study findings revealed a positive perception and use of TBA services by the respondents. This underlines the necessity for TBAs knowledge and skills to be improved within permissible standards through sustained partnership between TBAs and health systems. It is hoped that such partnership will foster a healthy collaboration between providers of orthodox and traditional maternity services that will translate into improved maternal and neonatal health outcomes in relevant settings.4Administration of misoprostol by trained traditional birth attendants to prevent postpartum haemorrhage in homebirths in Pakistan: a randomised placebo-controlled trial, N Mobeen,a J Durocher at. Al; 2010 Gynuity Health Projects Journal compilation RCOG 2010 BJOG An International Journal of Obstetrics and Gynaecology2010A randomised, double-blind, placebo-controlled triaA total of 1119 women giving birth at home.intervention=534 women and control=585 womenconsenting women were randomised to receive 600 lg oral misoprostol (n = 534) or placebo (n = 585) after delivery to determine whether misoprostol reduced the incidence of PPH (500 ml)Oral misoprostol was associated with a significant reduction in the rate of PPH (500 ml) (16.5 versus 21.9%; relative risk 0.76, 95% CI 0.590.97). There were no measurable differences between study groups for drop in haemoglobin >2 g/dl (relative risk 0.79, 95% CI 0.621.02); but significantly fewer women receiving misoprostol had a drop in haemoglobin >3 g/dl, compared with placebo (5.1 versus 9.6%; relative risk 0.53, 95% CI 0.340.83). Shivering and chills were significantly more common with misoprostol. There were no maternal deaths among participants.Postpartum administration of 600 lg oral misoprostol by trained TBAs at home deliveries reduces the rate of PPH by 24%. Given its ease of use and low cost, misoprostol could reduce the burden of PPH in community settings where universal oxytocin prophylaxis is not feasible. Continual training and skill-building for TBAs, along with monitoring and evaluation of programme effectiveness, should accompany any widespread introduction of this drug. Misoprostol may be the only feasible PPH prevention option, it should be endorsed as a safe and effective alternative intervention for use at home deliveries.5Georgina Msemo, Augustine Massawe et.al, Newborn Mortality and Fresh Stillbirth Rates in Tanzania After Helping Babies Breathe Training, Pediatrics 2013;131;e353; originally published online January 21, 2013; DOI: 10.1542/peds.2012-1795, http://pediatrics.aappublications.org/content/131/2/e353.full.html2012design was used for implementationHBB was implemented in 8 hospitals designated as study sites. Master trainers from the 3 major referral hospitals, 4 associated regional hospitals, and 1 district hospital were trained in the HBB program to serve as trainers for national disseminationA before(n = 8124) and after (n = 78 500)Implementation of HBB Training ProgramImplementation was associated with a significant reduction in neonatal deaths (relative risk [RR] with training 0.53; 95% confidence interval [CI] 0.430.65; P =.0001) and rates of FSB (RR with training0.76; 95% CI 0.640.90; P = .001). The use of stimulation increased from 47% to 88% (RR 1.87; 95% CI 1.821.90; P =.0001) and suctioning from 15% to 22% (RR 1.40; 95% CI 1.331.46; P =.0001) whereas face mask ventilation decreased from 8.2% to 5.2% (RR 0.65; 95% CI 0.600.72; P = .0001).HBB implementation was associated with a significant reduction in both early neonatal deaths within 24 hours and rates of FSB. HBB uses a basic intervention approach readily applicable at all deliveries. These findings should serve as a call to action for other resource-limited countries striving to meet Millennium Development Goal 46Gary L. Darmstadt, Anne CC Lee et.al, INTRAPARTUM-RELATED DEATHS: EVIDENCE FOR ACTION 5; 60 million non-facility births: Who can deliver in community settings to reduce intrapartum-related deaths?, International Journal of Gynecology and Obstetrics 107 (2009) S89S112, journal homepage: www.elsevier.com/locate/ijgo2009review the evidence for the effect of care by different community cadres during pregnancy and childbirth. we use GRADE criteria to assess the quality of evidence for the mortality-effect of these community-based providers on outcomes related to acute intrapartum hypoxiaSearches of the following databases of the medical literature were conducted: PubMed, Popline, EMBASE, LILACS, IMEM, African Index Medicus, Cochrane, and World Health Organization (WHO) documents.The initial search was conducted in November 2002, and was updated May 2009. Keyword searches relevant for this paper included birth asphyxia/asphyxia neonatorum, hypoxic ischaemic encephalopathy/hypoxic ischemic encephalopathy, neonatal encephalopathy, or neonatal mortality, and a combination of TBA/trained TBA/traditional birth attendant, community health worker/village health workers/community health aides, birthing center, skilled birth attendant/skilled attendant, or community midwives OR midwifery.N/A not an interventionThe evidence for providing skilled birth attendance in the community is low quality, consisting of primarily before-and-after and quasi-experimental studies, with a pooled 12% reduction in all cause perinatal mortality (PMR) and a 22%47% reduction in intrapartum-related neonatal mortality (IPR-NMR). Low/moderate quality evidence suggests that TBA training may improve linkages with facilities and improve perinatal outcomes. A randomized controlled trial (RCT) of TBA training showed a 30% reduction in PMR, and a metaanalysis demonstrated an 11% reduction in IPR-NMR. There is moderate evidence that CHWs have a positive impact on perinatal-neonatal outcomes. Meta-analysis of CHW packages (2 cluster randomized controlled trials, 2 quasi-experimental studies) showed a 28% reduction in PMR and a 36% reduction in early neonatal mortality rate; one quasi-experimental study showed a 42% reduction in IPR-NMR.Skilled childbirth care is recommended for all pregnant women, and community strategies need to be linked to prompt, high-quality emergency obstetric care. CHWs may play a promising role in providing pregnancy and childbirth care, mobilizing communities, and improving perinatal outcomes in low-income settings. Whilethe role of the TBA is still controversial, strategies emphasizing partnerships with the health system shouldbe further considered. Innovative community-based strategies combined with health systems strengthening may improve childbirth care for the rural poor, help reduce gross inequities in maternal and newborn survival and stillbirth rates, and provide an effective transition to higher coverage for facility births.More research is needed to determine the cost- effectiveness, sustainability, scalability and long-term impact, including neurodevelopmental outcomes, of such approaches. While the goal is to have a skilled attendant at every birth, innovative community strategies with health systems strengtheningmay provide childbirth care to the poor, help reduce the gross inequities in maternal and newborn survival and stillbirth rates, and provide an effective transition to higher coverage for facility births.7Sabin LL, Knapp AB, MacLeod WB, Phiri-Mazala G, Kasimba J, et al. (2012) Costs and Cost-Effectiveness of Training Traditional Birth Attendants to Reduce Neonatal Mortality in the Lufwanyama Neonatal Survival Study (LUNESP). PLoS ONE 7(4): e35560. doi:10.1371/journal.pone.0035560.2012LUNESP was a cluster-randomized trialAll TBAs and mothers who participated in the LUNESP trial, in an impoverished rural district in north-central Zambia among a population with limited access to health careA total of 120 TBAs were initially randomized to receive the intervention trainings and equipment, or to continue their existing standard of careAll TBAs received one clean delivery kit per birth for their regular TBA duties, which included a delivery sheet, cord cutter, cotton cord ties, latex gloves, and soap. Training for intervention TBAs commenced with 4-day sessions for each group of 30 TBAs, followed by 12 day refresher trainings approximately every 34 months for the duration of the trial. The trainings were conducted collaboratively by a US-based neonatologist and a local master trainer (a Zambian nurse-midwife), assisted by 68 Zambian facilitators. To demonstrate competency, intervention TBAs indicated skills retention at each retraining session. Each intervention TBA received one resuscitator mask, a polypropylene bottle with chlorinated water, and a laminated reference card summarizing NRP and trigger conditions for AFR. They also received each of the following per delivery: two flannel receiving blankets, a soft rubber bulb syringe, two 250 mg amoxicillin capsules, one 2-ounce mixing cup and spoon, and a 3 ml oral syringe. A more detailed description of the design, training, and analytic methods used in LUNESP has been published elsewhereWe calculated LUNESPs financial and economic costs and the economic cost of implementation for a forecasted ten-year program (20112020). In each case, we calculated the incremental cost per death avoided and disability-adjusted life years (DALYs) averted in real 2011 US dollars. The forecasted 10-year program analysis included a base case as well as conservative and optimistic scenarios. Uncertainty was characterized using one-way sensitivity analyses and a multivariate probabilistic sensitivity analysis. The estimated financial and economic costs of LUNESP were $118,574 and $127,756, respectively, or $49,469 and $53,550 per year. Fixed costs accounted for nearly 90% of total costs. For the 10-year program, discounted total and annual program costs were $256,455 and $26,834 respectively; for the base case, optimistic, and conservative scenarios, the estimated cost per death avoided was $1,866, $591, and $3,024, and cost per DALY averted was $74, $24, and $120, respectively. Outcomes were robust to variations in local costs, but sensitive to variations in intervention effect size, number of births attended by TBAs, and the extent of foreign consultants participation.Based on established guidelines, the strategy of using trained TBAs to reduce neonatal mortality was highly cost effective. We strongly recommend consideration of this approach for other remote rural populations with limited access to health care. Moreover, it shows that the cost-effectiveness of this strategy can likely be improved if implemented programmatically over a longer time horizon and with deliberate cost-saving measures. These results further strengthen the rationale for implementing programs similar to LUNESP in other disadvantaged communities with extremely limited access to health care.8Christopher J. Gilla,b, Nicholas G. Guerinac, et. Al., Training Zambian traditional birth attendants to reduce neonatal mortality in the Lufwanyama Neonatal Survival Project (LUNESP), Int J Gynaecol Obstet. 2012 July ; 118(1): 7782. doi:10.1016/j.ijgo.2012.02.0122012design was used for implementationpregnant women, their husbands, clinic staff, and TBAs; local village headmen and religious leaders98% of the TBAs considered farming as their primary vocation. Their educational level was low: 17% had never attended school and only 13% had progressed beyond primary school. The TBAs were members of the communitiesthey served, used clean delivery kits for every birth, and were registered, supported, and tracked by the Lufwanyama DHMT. On average, the intervention TBAs delivered 1.3 infants per month, or approximately 33 infants per TBA (interquartile range, 1644; maximum 112) during the study, which was conducted between September 2006 and November 2008.The study tested 2 interventions: a simplified version of the American Academy of Pediatrics neonatal resuscitation protocol (NRP); and antibiotics with facilitated referral (AFR).The LUNESP study showed that trained TBAs can be highly effective at reducing neonatal mortality in remote rural settings. Given how successful this strategy proved to be, it seems puzzling that TBAs are so rarely included in national health programs. Key elements that enabled the positive study result were: focusing on common and correctible causes of mortality; selecting a study population with high unmet public health need; early community mobilization to build awareness and support; emphasizing simplicity in the intervention technology and algorithms; using a traditional training approach appropriate to students with low literacy rates; requiring TBAs to demonstrate their competence before completing each workshop; and minimizing attrition of skills by retraining and reassessing the TBAs regularly throughout the study.An effective NRP training model was created that is suitable for community-based neonatal interventions, in research or programmatic settings, and by practitioners with limited obstetric skills and low rates of literacy.The skills and approaches adopted in LUNESP should be highly generalizable to other remote populations with limited access to health facilities.9L Keri, D Kaye, and K Sibylle, Referral practices and perceived barriers to timely obstetric care among Ugandan traditional birth attendants (TBA), Journal List Afr Health Sciv.10(1); Mar 20102010Qualitative methods All focus groups were held in Luganda, the local language familiar to all research participants.The six focus groups, which ranged in size from 5 to 12 participantsN/A not an interventionWhile TBAs, particularly those with previous training, appear willing to refer problematic pregnancies and labors, more serious problems exist that could lessen any positive effects of training. These problems include reported abuse by doctors and nurses, and seeing fistula as a disease caused by hospitals.Training of TBAs can be helpful to standardize knowledge about and encourage timely emergency obstetric referrals, as well as increase knowledge about the causes and preventions of obstetric fistula. However, for full efficacy, training must be accompanied by greater collaboration between biomedical and traditional health personnel, and increased infrastructure to prevent mistreatment of pregnant patients by medical staff.10Matendo et al. Reduced perinatal mortality following enhanced training of birth attendants in the Democratic Republic of Congo: a time-dependent effect, BMC Medicine 2011, 9:93 http://www.biomedcentral.com/1741-7015/9/932011That study was a population-based, prospective interventional study The number of communities selected from the DRC was determined by the sample size calculation for the FIRST BREATH Trial, and the number of deliveries observed was a function of the timing of the study periods for that trialBaseline data collection=Screened (n = 1,916), Consented (n = 1,893), Births < 1500 grams or missing (n = 26), Eligible for primary outcome (n = 1,867), Post ENC baseline data collection=Screened (n = 5,615), Consented (n = 5,612), Births < 1500 grams or missing (n = 84), Eligible for primary outcome (n = 5,528). Intervention group (NRP training): Screened (n = 2,930), Consented (n = 2,928), Births < 1500 grams or missing (n = 45), Eligible for primary outcome (n = 2,883) dan control group Screened (n = 3,365), Consented (n = 3,365), Births < 1500 grams or missing (n = 48), Eligible for primary outcome (n = 3,317)study conducted in two phases. In the first phase, theimpact of training using the ENC program was evaluated using an active baseline design. A period of prospective data collection was followed by ENC training and continuation of data collection. This phase was followed by a cluster randomized trial of training using an adaptation of the Neonatal Resuscitation Program (NRP: American Academy of Pediatrics and American Heart Association; 2000 edition). Communities were randomized to either receive NRP training (intervention communities) or to continue to provide care without additional training (control communities).More than two-thirds of deliveries were attended by traditional birth attendants and occurred in homes; these proportions decreased after ENC training. There was no apparent decline in perinatal mortality when the outcome of all deliveries prior to ENC training was compared to those after ENC but before NRP training. However, there was a gradual but significant decline in perinatal mortality during the year following ENC training (RR 0.73; 95% CI: 0.56-0.96), which was independently associated with time following training. The decline was attributable to a decline in early neonatal mortality. NRP training had no demonstrable effect on early neonatal mortality.Training DRC birth attendants using the ENC program reduces perinatal mortality. However, a period of utilization and re-enforcement of training may be necessary before a decline in mortality occurs. ENC training has the potential to be a low cost, high impact intervention in developing countries.A train-thetrainermodel appears to be effective; the use of this strategymay minimize the impact of the isolation of manyrural communities and their distance from sites of traditionalmedical education. Our findings suggest that implementationshould include a strategy for re-enforcementfollowing the initial training.11Wilson et.al, Effectiveness of strategies incorporating training and support of traditional birth attendants on perinatal and maternal mortality: meta-analysis, BMJ 2011;343:d7102 doi: 10.1136/bmj.d7102 (Published 1 December 2011)2011Systematic review with meta-analysisMedline, Embase, the Allied and Complementary Medicine database, British Nursing Index, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature, BioMed Central, PsycINFO, Latin American and Caribbean Health Sciences Literature database, African Index Medicus, Web of Science, Reproductive Health Library, and Science Citation Index (from inception to April 2011), without language restrictions. Search terms were birth attend*, traditional midwife, lay birth attendant, dais, and comadronas.six cluster randomised controlled trials (n=138 549) and seven non-randomised controlled studies (n=72 225) that investigated strategies incorporating training and support of traditional birth attendants.N/A not an interventionAll six randomised controlled trials found a reduction in adverse perinatal outcomes; our meta-analysis showed significant reductions in perinatal death (relative risk 0.76, 95% confidence interval 0.64 to 0.88, P