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www.umicore.com
For inquiries and additional information please contact
Umicore AG & Co. KG
Rodenbacher Chaussee 4
63457 Hanau-Wolfgang
Germany
Tel.: +49 (6181) 59 2471
Fax: +49 (6181) 59 [email protected]
www.umicore.com
For inquiries and additional information please contact
Umicore AG & Co. KG Rodenbacher Chaussee 4
63457 Hanau-WolfgangGermany
Tel.: +49 (6181) 59 2471Fax: +49 (6181) 59 2970
Let’s work together to create ground-breaking chemistry
www.umicore.com
For inquiries and additional information please contact
Umicore AG & Co. KG Rodenbacher Chaussee 4
63457 Hanau-WolfgangGermany
Tel.: +49 (6181) 59 2471Fax: +49 (6181) 59 2970
www.umicore.com
For inquiries and additional information please contact
Umicore AG & Co. KG Rodenbacher Chaussee 4
63457 Hanau-WolfgangGermany
Tel.: +49 (6181) 59 2471Fax: +49 (6181) 59 2970
www.pmc.umicore.com
Cross metathesis
Quick reference guide
Desired Product
Catalyst Temperature [oC] Concentration [molar]
M1
M1a
(C8
23)
M2
M2a
(C8
48)
M72
(C6
27)
M72
SIP
r (C
711)
M71
/ M
73
M73
SIP
r
MZ1
c (C
633)
MZ2
c (C
675)
-10 0 10 20 30 40 50 60 70 80 90 100 0.01 0.05 0.1 0.2 0.5 1.0 neat
R1
R2
R1
XR large
R2
R2
R2
R3
Alkyl
Alkyl
Alkyl
EWG
R1
R2
R1
XR large
R2
R2
R2
R3
Alkyl
Alkyl
Alkyl
EWG
R1
R2
R1
XR large
R2
R2
R2
R3
Alkyl
Alkyl
Alkyl
EWG
R1
R2
R1
XR large
R2
R2
R2
R3
Alkyl
Alkyl
Alkyl
EWG
R1
R2
R1
XR large
R2
R2
R2
R3
Alkyl
Alkyl
Alkyl
EWG
Recommended Best alternative Viable alternative * for Z-selective RCMX, Y, Z: functionalised carbons/heteroatoms
Desired Product
Catalyst Temperature [oC] Concentration [molar]
M1
M1a
(C8
23)
M2
M2a
(C8
48)
M72
(C6
27)
SI(o
-tol
) (C
571)
M71
/ M
73
MZ1
c (C
633)
MZ2
c (C
675)
-10 0 10 20 30 40 50 60 70 80 90 100 0.01 0.05 0.1 0.2 0.5 1.0 neat
Ring closing metathesis
X
X
Y
X
X
XR
Y
Y
Z
Z1-10
n
X
X
Y
X
X
XR
Y
Y
Z
Z1-10
n
X
X
Y
X
X
XR
Y
Y
Z
Z1-10
n
X
X
Y
X
X
XR
Y
Y
Z
Z1-10
n
X
X
Y
X
X
XR
Y
Y
Z
Z1-10
n
* *
