LacertaBioInc.

954LexingtonAvenue,#1005NewYork,NewYork10021

info@LacertaBio.com

+18452933343

Innovation&StrategicExcellenceinBusinessDevelopment

Ourbusinessisdedicatedtoassistingcompanieswiththeirbusinessdevelopmentandlicensingactivities

• Scouting• Search&evaluationoflicensingoracquisitionopportunities

• Out-Licensing• Fullrangeofout-licensingtoolsandcapabilities,includingChina&Central/SouthAmerica

• Auditing&Consulting• WereviewandanalyzeBDdepartmentsandprocesses,offeringkeyrecommendationsforimprovement

• Duediligence,valuation,independentopinions

• BDTraining• Live&Onlinetraining

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Problem:BusinessDevelopmentRequiresUnusualBlendofExpertiseandCapabilities

Formanycompanies,BDisanactivityoutsidenormalcorporateoperationsandexpertise…wefillthisgap.

• ExpertiseNeeded• In- andOut-licensingrequiresalarge,diversesetofskillsandexperiences

• Disruptions&Speed• Building&managinganewBDinfrastructuredisruptsdailyoperations

• Needbandwidthtodrivesuccess,evenwhensomeexpertiseispresent

• Questions&Issues• Presentations,conferences,IP,competition,valuation,financial,legal,regulatory,negotiation…

• Process&Tracking• Conferences,LinkedIn,QuantitativeTracking…

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Solution:CompleteSuiteofServicesandToolsToRunIn-OrOut-LicensingProcesses

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MultipleOutreachMethods

DatabaseInsights

QuantitativeTracking

Auditing

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Scouting&Out-Licensing

ScoutingFramework:EstablishSearchCriteria,ButCourseCorrectAsNewInformationBecomesAvailable

• Philosophy• Flexibleprocessismorelikelytouncovernon-obvious

ideaswhichdonotfitpreconceivednotions

• MultipleChannels• Neverdependentonanestablished,ever-changing

contactlist,weusemultiplechannelssimultaneously

• Conferencesincludedatnoextracost

• PauseandQuestion• Hubrisistheenemyofsuccess

• Criticaltoquestionallaspectsofprocess,andtoadjustaccordingtomarketrealities

• Results• Persistence,flexibility,andresponsivenessleadtomultiple

opportunitiesforevaluation

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Client-StatedRequirementsMustHave Optional

InitialSearchesDatabases ConferencesContacts Ideas

Pause&QuestionArewefindingopportunities?

Isprocessincorrect?

Narroworbroadcriteria?

Needmoreexoticideas?

CourseCorrect&Continue

CaseStudy:CompanyNeededRapidIncreaseinLate-StageScoutingToFillPendingRevenueGap

• Situation• CompanyneededPhaseIIIorlaterhospitalproduct

candidatestofillanticipatedrevenuegap

• Complications• Basedinsmallcountry,makingeconomicsunattractivefor

manyassetholders

• CompanylackedBDcapabilitiesandexpertise

• Approach• LacertaBioexecutedmulti-channelsearchinvolving

conferences,databases,anddigitaloutreach

• Criteriaadjustedbasedonothermarkets

• Results• Over200opportunitiesidentified

• Currentlyhave3inNegotiation/TermSheetstage

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MarketEntry:OurSuiteofCapabilities&RelationshipsAlsoAreApplicableForCompaniesSeekingUSEntry

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DevelopBusinessPlan• Understandingofcapabilities,strategy,&resources• Poseandassess“buildorbuy”&relatedquestions• PartnershipwithTitenare GXLprovidesexpandedskills

Design&ExecuteSearchandAssessment• Develop&executeplantoidentifyandassessopportunities• Modifyandcorrectasprocessunfolds• Partnerwithlegal&financialpartnersasneeded

OrganizationalImplementation• Establishinfrastructureasneeded• Developintegrationplans

Out-LicensingFramework:WeUtilizeMultipleChannelsForNetworkExpansion&MaximalMarketExposure

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• Philosophy• Out-licensingrequiresmorethanalistofcontacts…an

entiresuiteofapproachesnecessarytofindpartners

• DigitalChannels• WeareexpertsinutilizingournewsletterandLinkedInto

findwell-capitalizedsmallandmid-sizedcompanieswhicharehungryfordrugcandidates

• Conferences• Wecraftandcustomizepresentationsandmeetingtextto

maximizemeetingquantityandquality

• TrackingandReporting• Weprovideclientswithquantitativeprogressreportsin

realtime,enablingfrequent“coursecorrection”ifneeded

• Detailsoncompletedprojectsavailablebyrequest

Databases:InsightfulSearchesToMinimizeWastedEffort

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• MedTrack• Powerfulsearchcapabilitiestoidentifyin-licensingorout-

licensingopportunities

• Flexible• Searchescanbereadilyperformedforspecific

geographies,stagesofdevelopment,orotherfactors

• Contacts• Manycompanyprofilesincludenames,phonenumbers,

andemailaddressesofkeycontacts…perfectforoutreach

• Supplementation• WesupplementMedTracksearcheswithotherdatabases,

suchasthosefrompriorconferences

• WearealsoquiteactiveinLinkedIn,enablingustoidentifykeypersonnelforoutreach

Tracking:QuantitativeTrackingEnsuresWeAreMeetingClientExpectationsforOutreachPaceandDealFlow

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• WhatItIs• Clientshaveaccesstoreal-timequantitativetracking,via

easy-to-understandspreadsheetsandgraphics

• BenefitstoClient• EasytomonitorLacertaBioefforts

• Dataavailableforinternalreporting

• WhatWeTrack• Allcommunicationswithallpotentialpartnersarelogged

• Spreadsheetgrowsverticallyascompaniesareadded,andhorizontallyascommunicationsmoveforward

• EasytoUnderstand• Graphicsaresimpleandeasytounderstand,suitablefor

reportsandpresentations

OurServices&CapabilitiesArePerfectforInvestorsandCompaniesSeekingInvestment

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Scouting• SourcingandAssessingpotentialinvestorsorinvestmentopportunities

• Anonymoussourcingensuresthatonlyopportunitieswhichfitarebroughtforward

DueDiligence• SecondaryMarketResearch• MedTrack/PipelineAnalysis• KOLinterviewsandsurveys• Valuation

SecondOpinions• Independentassessmentsandvaluationspriortoinvestmentcommitments

Licensing/Exits• Fundraising,out-licensing,andothertransactionalservicesandprocesses

• Businesscases• Conferences,Otheroutreach

ServicesForInvestmentCommunity

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Auditing,Consulting,&Training

BDAudits:WeApplyRigorousFrameworksToEvaluateAndCorrectSuboptimalOut-LicensingEfforts

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• Framework• Wedevelopedandapplyafour-moduleframeworktoreview,assess,andcorrectunsatisfactoryout-licensingprocesses

• Report&Benefits• Deliverableisadetailedanalysisofeverythingfromindividualslidestoresponsiblepersonnel,enablingmanagementtomakethenecessarychangestoimprovetheirout-licensingprocess.

Consulting:WeBringSubjectMatterExpertsAsNeeded

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• NorthAmericancompanyrequiredvaluationanddealtermsanalysisforapotentialout-licensingtransactionforoneassetacrossmultipleindicationsSituation

Complications

Approach

Result

• LicensewasforChinesemarket;localexpertisewasrequiredforclinical,regulatory,andpricing/reimbursement

• SecuredservicesofShanghai-basedconsultanttoassistwithvaluation• Otherlocalcontactsbroughtittoprovidedata,input,andfeedback

• Complexvaluationmodelsdelivered• Transactionundernegotiation

Training:WeDevelopandProvideTrainingProgramsonVariousAspectsofBusinessDevelopment

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• Ourupcomingclassfocusesonthemarketingaspectsofout-licensing:presentations,meetinginvitations,dataroomorganization,andotherpracticalmatters

• Seehttps://ebdgroup.knect365.com/outlicensing-online-course/fordetails

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Partnerships&People

ClinicalNetworkSolutions:IntelligentlyIntegratedDrugDevelopmentServices

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• Consulting• CMC,Tox,Clinical,RegulatoryAffairs,MedicalWriting,andotherservices

• Experienceacrossmultipletherapeuticareasandstagesofdevelopment

• ClinicalOperations• Over250clinicalstudiesmanaged• ExtensiveBiostatisticsexpertise

• TaxIncentives• Australiansubsidiariesreceive43.5%cashtaxrefundsforR&DspentinAustraliaAustralia|NewZealand|UnitedKingdom|UnitedStates

Leadership – CarlosN.Velez,Ph.D.,MBA

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• FounderandManagingPartnerofLacertaBio (2010).

• Co-founderofConnexinTherapeutics,anophthalmologydrugdevelopmentcompanycurrentlyraisingaSeed/SeriesAroundoffinancing.

• PreviouslytheChiefBusinessOfficerofLanticTherapeutics(UK)untilthepassingofthescientificco-founderin2012.

• FormerDirectorofBusinessDevelopmentatPenwestPharmaceuticals,responsiblefortheout-licensingofinternal505(b)(2)programsandthescoutingandanalysisofin-licensingopportunitiesinneurology.

• OtherpreviousemployersincludeForestLabs,FrankelGroup(nowHuronConsulting)andGenencor(nowownedbyDanisco).

• B.S.,Pharmacy,AlbanyCollegeofPharmacy;Ph.D.,Pharmacy,UniversityofNorthCarolinaatChapelHill;MBA,Finance,RochesterInstituteofTechnology.

KeyAssociates– ExpertiseAsNeeded

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• NineBridgesCapital&VentacPartners,Shanghai

• 20+yearsexperienceinpharma/biotechtransactions,fundraising,andadvisory

• Extensiveexpertiseinfinancialmodelingandvaluation

• Formeremployers:PainTherapeutics,OnyxPharmaceuticals,Chiron,Novartis,Roche

• BS,MichiganStateUniversity;MBA,ErasmusUniversity

JonathanMyers-

China

• Adya Consulting,Lugano

• 20+yearsexperienceR&D,inpharma/biotechtransactions,venturecapital,andadvisory

• Fundraising,managementandBoard-levelexperience

• Formeremployers:I-BankersSecurities,BSIHealthCapital,Quintiles,Bracco

• BS,Ph.D.,UniversityofMilan

SilviaPanigone,Ph.D.-

Switzerland

SomeOfOurSatisfiedClients

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ContactUs

LacertaBioInc.

954LexingtonAvenue,#1005NewYork,NewYork10021

info@LacertaBio.com

+1845293334321