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Klinik und Poliklinik für Augenheilkunde
All authors have no financial interest in the subject matter of this poster.
R. Khoramnia, J. P. Salgado, C.P. Lohmann, C. Winkler von Mohrenfels
ASCRS 2011
Comparison Between Central Corneal Thickness Measurements in Healthy Eyes Using a New Device and 2 Other Methods
Purpose
Klinik und Poliklinik für Augenheilkunde
The TMS-5 (Tomey) is a new device for the examination of the anterior eye
segment combining Placido- and Scheimpflug-Technology. The purpose of this
study was to compare central corneal thickness (CCT) measurements using
TMS-5, LenStar/Allegro Biograph (Haag-Streit/WaveLight), and the gold
standard ultrasonic pachymetry (Pachymeter SP-3000, Tomey).
TMS-5
Foto: www.ophthalworld.de
Allegro Biograph/LenStar
Foto: www.wavelight.com
SP-3000
Foto: www.eyenovation.de
Material and methods
Klinik und Poliklinik für Augenheilkunde
48 eyes of 24 healthy volunteers were included in this comparative study. In all
eyes, CCT was measured with the TMS-5 (Tomey, Nagoya, Japan), LenStar
(Haag-Streit AG, Koeniz, Switzerland)/Allegro Biograph (WaveLight AG,
Erlangen, Germany), and ultrasonic pachymetry (Pachymeter SP-3000, Tomey,
Nagoya, Japan). The values obtained from the different devices were compared
using Bland-Altman plots and linear regression.
Results I
Klinik und Poliklinik für Augenheilkunde
The mean CCT readings with the TMS-5, LenStar/Allegro Biograph, and
ultrasound were 516.6 µm, 535.7 µm, and 543.6 µm, respectively.
Regression analysis showed a high correlation between the values
obtained with the TMS-5 and the LenStar/Allegro Biograph (r=0.950,
p<0.001) and the values obtained with the TMS-5 and ultrasound (r=0.918,
p<0.001).
Results II
Klinik und Poliklinik für Augenheilkunde
Compared to the LenStar/Allegro Biograph and ultrasound, the TMS-5
underestimated the CCT. The mean differences were -19.1 µm compared
to the LenStar/Allegro Biograph and -27.0 µm compared to ultrasound as
shown in the Bland-Altman plots.
Conclusion
Klinik und Poliklinik für Augenheilkunde
• Regression analysis showed a high correlation between the values obtained with
the TMS-5 and the LenStar/Allegro Biograph and the values obtained with the
TMS-5 and ultrasound.
• However, the TMS-5 underestimated the CCT compared to the LenStar/Allegro
Biograph and ultrasound.
Therefore, the TMS-5, LenStar/Allegro Biograph, and ultrasound should not
be used interchangeably for the measurement of CCT.
Name der KlinikKlinik und Poliklinik für Augenheilkunde
Contact:
Klinikum rechts der Isar Tel.: +49 89 4140 – 2310Technische Universität München Fax: +49 89 4140 – 4076 Klinik und Poliklinik für Augenheilkunde Email: [email protected] Str. 22 www.med.tum.de81675 Munich www.augenklinik.med.tum.deGERMANY