Journal of Clinical Pathology HAR11i;fOE

January 1984 Vol 37 No 1 Wm

Contents

Distribution of the Ca (Oxford) antigen in lung neoplasms and non-neoplastic lung tissues FJ PARADINAS,G BOXER, KD BAGSHAWE page 1A study of the Ca antigen in epithelial tumours of the ovary AM FERGUSON, H FOX page 6Evaluation of the Cal antibody in the diagnosis of invasive breast cancer DGF CLOUGH, GR COGHILL,MP HOLLEY page 10Immunohistochemical detection of Ca antigen in normal, dysplastic and neoplastic squamous epithelia ofthe human uterine cervix JM LLOYD, T O'DOWD, M DRIVER, DEH TEEpage 14The larger bronchi in byssinosis: a morphometric study C EDWARDS, A CARLILE, G ROOKEpage 20Spiral organisms in endoscopic biopsies of the human stomach TP ROLLASON, J STONE, JM RHODES page 23Renin in renal cell carcinoma-an immunocytochemical study using an antibody to pure humanrenin GBM LINDOP, S FLEMING page 27Chronic coronary periarteritis in two patients with chronic periaortitis MJ MITCHINSON, DGD WIGHT, J ARNO,BB MILSTEIN page 32Immunohistochemical localisation of factor VIII-related antigen in Hodgkin's disease J CROCKER, PJ SMITHpage 37Intracellular inclusion bodies in 14 patients with B cell lymphoproliferative disorders 0 PETERS,C THIELEMANS, L STEENSSENS, M DE WAELE, W HIJMANS, B VAN cAmppage 45Distribution of ferritin, transferrin and lactoferrin in breast carcinoma tissue R ROSSIELLO, MV CARRIERO,GG GIORDANO page 51The fibrinolytic system in pre-eclampsia L GOW, DM CAMPBELL, D OGSTONpage 56Splenic siderosis and parenteral iron dextran in maintenance haemodialysis patients JA MURRAY, DN SLATER,MA PARSONS, M FOX, S SMITH, MM PLATTS page 59Automated detection of micro-organisms in blood cultures by means of the Malthus MicrobiologicalGrowth Analyser DFJ BROWN, M WARNER, CED TAYLOR, RE WARREN page 65Development and evaluation of a miniaturised method as an aidto the identification of clinically importantanaerobic bacteria PN LEVElT page 70 ..Disseminated toxoplasmosis in cardiac transplantation CGA MCGREGOR, DG FLECK, J NAGINGTON, PGI STOVIN,R CORY-PEARCE, TAH ENGLISH page 74Disseminated petriellidiosis (allescheriasis) in a patient with refractory actue lymphoblasticleukaemia LY SHIH, N LEEpage 78The Howie Code: what are the real costs? CH COLLINS, JW HOWIEpage 83Pathophysiology of human lipoprotein receptors: clinical consequences of a cellular defect J SHEPHERD,CJ PACKARD page 87Comparative trial of six methods for the detection of CMV antibody in blood donors AF HUNT, DL ALLEN,RL BROWN, BA ROBB, AY PUCKETT, CC ENTWISTLEpage 95Technical methodsA selective enrichment broth for the isolation of Clostridium difficile SHEILA O!FARRELL, M WILKS, JQ NASH,S TABAQCHALI page 98Rapid demonstration of nucleic acids using "oxidised" gallocyanin and chromic potassium sulphate:methods and applications OAN HUSAIN, KC WATrs page 99Letters to the Editor page 101Book reviewspage 105Some new titles page 106Corrections page 107

ASTM CODEN: JCPAAK 37(1) 1-108 (1984) ISSN 0021-9746

on February 27, 2020 by guest. P

rotected by copyright.http://jcp.bm

j.com/

J Clin P

athol: first published as on 1 January 1984. Dow

nloaded from

ContentsNo 1 JANUARY 1984

PageDistribution of the Ca (Oxford) antigen in lung neoplasms and non-neoplastic lung tissues FJ PARADINAS, G BOXER, KD BAGSHAWE 1A study of the Ca antigen in epithelial tumours of the ovary AM FERGUSON, H FOX ....................................... 6Evaluation of the Cal antibody in the diagnosis of invasive breast cancer DGF CLOUGH, GR COGHILL, MP HOLLEY .... .......... 10Immunohistochemical detection of Ca antigen in normal, dysplastic and neoplastic squamous epithelia of the human uterinecervix JM LLOYD, T O'DOWD, M DRIVER, DEH TEE ....... ................................................................ 14

The larger bronchi in byssinosis: a morphometric study c EDWARDS, A CARLILE, G ROOKE .................................. 20Spiral organisms in endoscopic biopsies of the human stomach TP ROLLASON, J STONE, JM RHODES ..... ..................... 23Renin in renal cell carcinoma-an immunocytochemical study using an antibody to pure human renin GBM LINDOP, S FLEMING 27Chronic coronary periarteritis in two patients with chronic periaortitis MJ MITCHINSON, DGD WIGHT, J ARNO, BB MILSTEIN ...... 32Immunohistochemical localisation of factor VlII-related antigen in Hodgkin's disease J CROCKER, PJ SMITH .... .............. 37Intracellular inclusion bodies in 14 patients with B cell lymphoproliferative disorders o PETERS, C THIELEMANS, L STEENSSENS,M DE WAELE, W HIJMANS, B VAN CAMP ........ ........................................................................ 45Distribution of ferritin, transferrin and lactoferrin in breast carcinoma tissue R ROSSIELLO, MV CARRIERO, GG GIORDANO .... .... 51The fibrinolytic system in pre-eclampsia L GOW, DM CAMPBELL, D OGSTON ............................................... 56Splenic siderosis and parenteral iron dextran in maintenance haemodialysis patients JA MURRAY, DN SLATER, MA PARSONS, M FOX,S SMITH, MM PLATTS ................ ........................................................................ 59

Automated detection of micro-organisms in blood cultures by means of the Malthus Microbiological Growth AnalyserDFJ BROWN, M WARNER, CE:D TAYLOR, RE WARREN ...... ................................................................. 65Development and evaluation of a miniaturised method as an aid to the identification of clinically important anaerobic bacteriaPN LEVETT ....................................................................................................... 70

Disseminated toxoplasmosis in cardiac transplantation CGA MCGREGOR, DG FLECK, J NAGINGTON, PGI STOVIN, R CORY-PEARCE,TAH ENGLISH ...................................................................................................... 74Disseminated petriellidic,sis (allescheriasis) in a patient with refractory acute lymphoblastic leukaemia LY SHIH, N LEE ....... 78The Howie Code: what are the real costs? CH COLLINS, JW HOWIE ..................................................... 83Pathophysiology of human lipoprotein receptors: clinical consequences of a cellular defect J SHEPHERD, CJ PACKARD .... ..... 87Comparative trial of six methods for the detection of CMV antibody in blood donors AF HUNT, DL ALLEN, RL BROWN, BA ROBB,AY PUCKETT, CC ENTWISTLE ........ ................................................................................. 95

Technical methodsA selective enrichment broth for the isolation of Clostridium difficile SHEILA O FARRELL, M WILKS, JQ NASH, S TABAQCHALI 98Rapid demonstration of nucleic acids using oxidised"gallocyanin and chromic potassium sulphate; methods and applicationsOAN HUSAIN, KC WA1TS ............................................................................................ 99

Letters to the Editor.............................................................................................. 101Book reviews .................................................................................................... 105Some new titles ................................................................................................... 106Corrections .................................................................................................... 107

No 2 FEBRUARY 1984

Review articleInterferons PG HIGGINS ............................................................................................ 109Detection of Clostridium diffrile in faeces by direct gas liquid chromatography PN LEVETT ................................ 117Isolation of Chlamydia using McCoy cells and Buffalo green monkey cells PJ WILLIS, L JOHNSON, RG THOMPSON .... .......... 120Rapid detection of antibodies against cytomegalovirus induced immediate early and early antigens by an enzyme linkedimmunosorbent assay MONICA MUSIANI, CRISTINA CARPI, MARIALUISA ZERBINI .............................................. 122Human papillomavirus infection of the uterine cervix: histological appearances in 28 cases identified by immunohistochemicaltechniques JL DYSON, PG WALKER, A SINGER ....... ................................................................... 126Demonstration of an epitope of the transferrin receptor in human cervical epithelium-a potentially useful cell marker JM LLOYD,T O'DOWD, M DRIVER, DEH TEE ........ ............................................................................... 131Detection and distribution of aluminium in bone J DENTON, Al FREEMONT, J BALL ........... . ............................... 136Primary tumorous aldosteronism due to a black adrenal adenoma: a light and electron microscopic study IK SIENKOWSKI,RM WATKINS, VER ANDERSON .1.......................................................................................143Comparison of methods to identify microglial cells and macrophages in the human central nervous system MARGARET ME ESIRI, IBOOSS ............................................................................................................ 150Computerisation of histopathology/cytology records-use of a commercial data storage system SG SUBBUSWAMY, A MCCORMICK, EEPETERS ........................................................................................................... 157Glandular duodenal carcinoid-a somatostatin rich tumour with neuroendocrine associations DFR GRIFFITHS, B JASANI,GR NEWMAN, ED WILLIAMS, GT WLLIAMS ....... ....................................................................... 163

Malignant Warthin's tumour: an ultrastructural study LJR BROWN, SR APARICIO ........................................... 170Glomerulonephritis with coexistent immune deposits and antibasement membrane activity S RAJARAMAN, JS PINTO, T CAVALLO 176Assessment of platelet function in patients with Raynaud7s syndrome RA HUTTON, DP MIKHAILIDIS, RM BERNSTEIN, JY JEREMY,GRV HUGHES, P DANDONA ........................................................................................... 182Normal values for peripheral blood white cell counts in women of four different ethnic origins BARBARA BAIN, MARY SEED,I GODSLAND ....................................................................................................... 188Lack of correlation between factor VIII related antigen multimeric analysis pattern and parallel or non-parallel dose responsecurves in an ELISA factor VIII related antigen assay PE SHORT, CE WILLIAMS, MS ENAYAT, AM PICKEN, FGH HILL.194

on February 27, 2020 by guest. P

rotected by copyright.http://jcp.bm

j.com/

J Clin P

athol: first published as on 1 January 1984. Dow

nloaded from

ContentsPage

Selenium and vitamin E in relation to risk factors for coronary heart disease NIA ELLIS, BARBARA LLOYD, RS LLOYD,BARBARA E CLAYTON.................................................. 200C reactive protein: an aid to assessment and monitoring of acute pancreatitiS AD MAYER, MJ MCMAHON, MARGARET BOWEN,EH COOPER..................................................... 207Measurement of biliary alkaline phosphatase by mini-column chromatography and by electrophoresis and its application to thedetection of liver metastases in patients with breast cancer CAROL KARMEN, PD MAYNE, A YING FOO, S PARBHOO, 5B ROSALKI 212Comparison of a new tumour marker, CA 1 9_.9TM with ca-fetoprotein and carcinoembryonic antigen in patients with uppergastrointestinal diseaseS H JALANKO, P KUUSELA, P ROBERTS, P SIPPONEN, CAJ HAGLUND, 0 MAKELA................ 218Endogenous avidin-binding activity in human lymphoid tissue D BANERJEE, S PETTIT .................... 223Technical methodSerum glucose agar, a transport medium for Streptococcus-pyogeneS ELIZABETH M PERKS, RT MAYON-WHITE ........... 226Letters to the Editor ................................................ 228Book reviews.................................................... 230Notices.......................................................232

No 3 MARCH 1984

Lymphoproliferations in the bone marrow: identification and evolution, classification and staging R BARTL, B FRISCH, R BURKHARDT,K JAGER, R PAPPENBERGER, G HOPFMANN-FEZER...................................... 233Detection and identification of serum monoclonal immunoglobulin by immunoisoelectric focusing. Limits of sensitivity and useduring relapse of multiple myeloma D SINCLAIR, DS KUMARARAT-NE, Di sTolTr........................ 255Measurement of serum C reactive protein concentration after bone maffow transplantation for leukaemia IF ROWE, AM WORSLEY,P DONNELLY, D CATOVSKY, JM GOLDMAN, DAG GALTON, MB PEPYS .............................. 263A quantitative study of eosinophil polymorphs in Hodgkin's disease WJ FUGGLE, JCROCKER, Pi sumiH............. 267Tuberous sclerosis: unusual associations in four caseS EB ILGREN, D WESTMORELAND..................... 272Hepatic metastases in a case of intravascular bronchioloalveolar tumour ANN GLEDHILL, iM KAY............... 279Small intestinal mucosal abnormalities in post-perinatal deaths S VARIEND, R SUNDERLAND.................. 283Histochemical demonstration of acetylcholinesterase in neuroblastoma S VARIEND, MA LOUGHUN............... 288Increased a-fetoprotein concentration in association with ileal adenocarcinoma complicatiAg Crohn' s disease M LEADER, JR JASS 293Intestinal lactase, sucrase, and alkaline phosphatase in 373 patients with coeliac disease JG O'GRADY, FM STEVENS, R KEANE, EMCRYAN, B EGAN-MITCHELL, B MCNICHOLL, CF MCCARTHY, PF FOTrRELL............................. 298Exocrine pancreatic function in diabetes mellitUS P DANDONA, DB FREEDMAN, Y FOO, J PERKINS, A KATRAK, DP MIKHAILIDIS, SBROSALKI, AG BECKETT................................................. 302Increased angiotensin-converting enzyme activities in diabetes mellitus: analysis of diabetes type, state of metabolic control andoccurrence of diabetic vascular disease G SCHERNTHANER, CM SCHWARZER, R KUZMITS, MM MULLER, U KLEMEN, H FREYLER..... 307Measurement of total bile acids in gastric juice BJ COLLINS, PCH WATT, THERESA 0 REILLY, RJ MCFARLAND, AHG LOVE....... 313Colorimetric enzymatic measurement of serum total 3a-hydroxy bile acid concentrations without extraction MY QURESHI, SMSMITH, GM MURPHY.................................................. 317Comparison of results from two antibiotic susceptibility testing trials that formed part of the United Kingdom national externalquality assessment scheme JJS SNELL, DFJ BROWN, PS GARDNER.............................. 321A modified azoalbumin technique for the assay of proteolytic enzymes for use in blood group serology PK PHILLIPS, DILYS PRIOR, BDAWES ....................................................... 329Comparison of the sensitivity of three methods for the rapid identification of Cryptococcus neoformans J COHEN ....... 332Neutropenic enterocolitis due to Clostridium septicum infection A KING, ANITA RAMPLING, DGD WIGHT, RE WARREN ....... 335Identification of the Enterobacteriaceae: a comparison of the Enterotube II with the API 20E LI HAYEK, GW WILLIS...... 344Is the antimicrobial removal device a cost-effective addition to conventional bloodi cultures? ROSEMARY MUNRO, Pi COLLIGNON,TANIA C SORRELL, P TOMLINSON ............................................ 348Technical methodImage analysis--a quantitative technique for studying normal and diseased microvasculature RAi SPENCE, R MCCONNELL, iM SLOAN,IV ALLEN...................................................... 352Letters to the Editor................................................. 354Book reviews.................................................... 356

No 4 APRIL 1984

Basement membrane and apocrine epithelial antigens in differential diagnosis between tubular carcinoma and sclerosing adenosisof the breast P EKBLOM, M MIETTINFN, LISBFT-H FORSMAN, LC ANDERSSON .......................... 357Immunocytochemistry in the identification of vascular invasion in breast cancer R BETrELHEIM, D MITCHELL, BA GUSTERSON 364Use of NKI C3 monoclonal antibody in the assessment of benign and malignant melanocytic lesionS RONA H MACKIE, IRENECAMPBELL, MARLYN L TURBITIT.............................................. 367Small intestinal mucosal fat in childhood enteropathies S VARIEND, MONICA PLACZEK, F RAAFAT, iA WALKER-SMITH........ 373Argyrophil cells in normal, hyperplastic, and neoplastic endometriUM E SIVRIDIS, CH BUCKLEY, H FOX............. 378Pituitary adenomas producing growth hormone in acromegalic patientS LESLEY A SMALLMAN, PiS DUNN, RC CURRAN, DR LONDON 382Pulmonary infiltrates in immunocompromised patients: diagnosis by cytological examination of bronchoalveolar lavagefluid JENNIFER A YOUNG, iM HOPKIN, WP CUTHBERTSON.................................. 390

on February 27, 2020 by guest. P

rotected by copyright.http://jcp.bm

j.com/

J Clin P

athol: first published as on 1 January 1984. Dow

nloaded from

Contents

Page

When is it an osteoclast? M KAYE .......................................... 398Removal of formaldehyde and xylene fumes from histopathology laboratories: a functional approach to the design of extractionsysteMS FP EDWARDS, AR CAMPBELL.......................................... 401An external quality assessment scheme in histopathology ANTHEAJ SHERWOOD, AC HUNT .................. 409Evolution of a national urine quality assurance programme: the Australasian experience, 198 1-1983 MDS SHEPHARD, LAPENBERTHY. CG FRASER................................................ 415Pseudomonas in the sinks in an intensive care unit: relation to patients MH LEVIN, B OLSON, CATHERINE NATHAN, SA KABINS, RAWEINSTEIN..................................................... 424Inhibitory effect of cerebrospinal fluid on the growth of meningococci and pneumococci M HASSAN-KING, HC WHITIrLE, BMGREENWOOD..................................................... 428Heterotypic reactions in a radioimmunoassay for coxsackie B virus specific 1gM SF PUGH.................. 433An immunoperoxidase assay for the detection of specific IgA antibody in Epstein-Barr virus infectionS R CEVENINI, M DONATI, FRUMPIANESI, A MORONI, P PAOLUCCI........................................... 440Vitamin D nutrition in pregnant women at term and in newly born babies in Saudi Arabia F SERENIUS, ATH ELIDRISSY, P DANDONA 444Investigation of the organelle pathology of skeletal muscle in chronic alcoholiSM FC MARTIN, G SLAVIN, AJ LEVI, Ti PETERS .... 448Observed activities of serum creatine kinase: total and B subunit activity and other enzymes in young persons abusing solventS RJSPOONER, RC BIRRELL, AS MCLELLAND, JA BAIRD, I SOURINDHRIN ....................... ....... 455Increased serum IgE concentrations during infection and graft versus host disease after bone marrow transplantation SA WALKER,TR ROGERS, D PERRY, JR HOBBS, PAMELA G RICHES..................................... 460Serum paraproteins in chronic lymphocytic leukaemia D SINCLAIR, JH DAGG, AM MOWAT, DELPHINE MV PARROIT, DI STOTTr..... 463Endotoxaemia as a cause of fever in immunosuppressed patients RI HARRIS, PCW STONE, GR EVANS, J STUART.......... 467Acquired immunodeficiency syndrome in a patient with no known risk factors: a pathological study AD BURT, GRACE SCOTr,CAROLINE R SHIACH, CG ISLES ............................................. 471Technical methodSelection and use of a method for the culture of blood leucocyt~s to reveal the fra(x) site iS H.ASLAM, RG CHITHAM, JW TAYLOR., VANNESS ...................................................... 475Letters to the Editor ................................................ 477Book reviews.................................................... 480Some new titles................................................... 480Notices ...................................................... 480Correction..................................................... 480

No 5 MAY 1984

Varied light and scanning electron microscopic appearances of barium sulphate in smears and histological sectionS DA LEVISON, PRCROCKER, A SMITH, AJ BLACKSHAW, CI BARTRAM...................................... 481Unusual histological appearances of barium sulphate-a case report with scanning electron microscopy and energy dispersive x rayanalysis C WOMACK................................................. 488Cortical microcystic disease of the kidney with dominant inheritance: a previously undescribed syndrome SC MELNICK, DB BREWER,iS OLDHAM..................................................... 494Tumour-associated eosinophilia in the bladder D LOWE, CDM FLETCHER, RL GOWER ....................... )Primary choriocarcinoma of the bladder evolving from a transitional cell carcinoma PM DENNIS, AG TURNER.......... 503Relation between intragastric bile acid concentration and mucosal abnormality in the stomach after vagotomy andgastroenterostomy for duodenal ulcer PCH WATrr, JM SLOAN, TL KENNEDY........................ 506Relation between gastric histology and gastric juice pH and nitrite and N-nitroso compound concentrations in the stomach aftersurgery for duodenal ulcer PCH WATr, JM SLOAN, JOAN DONALDSON, G CAMPBELL, TL KENNEDY................. 511Crohn's disease of the gall bladder J MCCLURE, SS BANERJEE, PS SCHOFIELD......................... 516A quantitative study of mast- cellIs in Hodgkin's disease J CROCKER, PJ SMITHi........................ 519Antithrombin III metabolism in patients with liver disease EAR KNOT, JW TEN CATE, HR DRIJFHOUT, LH KAHLE, GN TYGAT 523Pepsinogen synthesis and secretion in isolated gastric glands J DEFIZE, G PALS, RR FRANTS, BD WESTERVEL D, SGM MEUWISSEN, AWERKISSON..................................................... 531Collagen stimulating factors from lung in experimental paraquat poisoning demonstrated in vitro and in vivo WD THOMPSON, RSPATRICK...................... ............................... 3

Collagen stimulating factors in hepatic fibrogeneSIS A FALLON, iF BRADLEY, J BURNS, J OD MCGEE............... 542Patterns of chronic liver disease in Kuwait with special reference to localisation of hepatitis B surface antigen MS AL ADNANI, SMALI ........................................................ 549Widespread distribution in human tissues of an antigenic determinant of granulocyteS AJ HOWIE, G BROWN, AMANDA G FISHER, M

KHAN.................... ..............................555Localisation of factor XIII in human tissues using an immunoperoxidase technique Jo FEAR, P JACKSON, C GRAY, KJA MILOSZEWSKI,MS LOSOWSKY.................................................... 560Chronic lymphocytic leukaemia terminating in acute myelofibrosiS ANNE L LENNARD, Si PRocTOR ............... 64Effect of volume of blood cultured on detection of Streptococcus viridans bacteraemia DC SHANSON, F THOMAS, D WILSON 68Anomalous results using countercurrent immunoelectrophoresis for the detection of pneumococcal antigen in Bactec blood culturemedia WENDY CHAN CHIANG, OS TILLOTSON, MAEVE GL KEANEY, LEELA A GANGULI....................... S71Evaluation of a commercial antibody capture enzyme immunoassay for the detection of rubella specific IgM J HODGSON, P

MORGAN-CAPNER................................................... 573

on February 27, 2020 by guest. P

rotected by copyright.http://jcp.bm

j.com/

J Clin P

athol: first published as on 1 January 1984. Dow

nloaded from

ContentsPage

Prospective study of the human polyomaviruses BK and JC and cytomegalovirus in renal transplant recipients SD GARDNER, EFDMACKENZIE, C SMITH, AA PORTER ......... ............... ............................................................ 578Rectal organ culture as a model for the investigation of bacterial adhesion and invasion RJ DICKINSON, WJ BRANCH, RE WARREN, GNEALE ........................................................................................................... 587The bacteriology of infected malignant ulcers vo ROTIMI, FA DUROSINMI-ETn ............................................. 592Technical methodAutomated method of nitrite estimation in gastric juice PCH WATT, JOAN D DONALDSON .............. .. ................... 596Letters to the Editor .............................................................................................. 597Book reviews ................................................................................................. 600Some new titles ................................................................................................. 600Notice ................................................................................................. 600Correction.................................................................................................. 600

No 6 JUNE 1984

Increased numbers of IgE containing cells in gastric and duodenal biopsies. An expression of food allergy secondary to chronicinflammation? JP VAN SPREEUWEL, J LINDEMAN, J VAN MAANEN, CJLM MEYER .............................................. 601Mucin histochemistry of the columnar epithelium of the oesophagus (Barrett's oesophagus): a prospective biopsy study MPEUCHMAUR, F POTET, D GOLDFAIN .................................................................................... 607Healing of cervical epithelium after laser ablation of cervical intraepithelial neoplasia GLM SHARP, JW CORDINER, EL MURRAY, IARMORE ............................................................................................................ 611Epidermal Langerhans' cells in Behpet's disease SARAH KOHN, S HAIM, A GILHAR, R FRIEDMAN-BIRNBAUM, I NIR ....... ......... 616Histiocytic and dentritic reticulum cells shown by a zinc iodide-osmium technique J CROCKER, MARY HOPKINS ....... ......... 620Method for the simultaneous labelling of terminal deoxynucleotidyl transferase (TdT) and membrane antigens J TAVARES deCASTRO, JF SAN MIGUEL, J SOLER, D CATOVSKY ........ ...................... . ............................................ 628Rapid processing of fetal skin for prenatal diagnosis by light and electron microscopy RAJ EADY, DB GUNNER, MJ TIDMAN, KHNICOLAIDES, CH RODECK ...................... 633Effects of fixation and enzymatic digestion on the immunohistochemical demonstration of laminin and fibronectin in paraffinembedded tissue P KIRKPATRICK, AJ D'ARDENNE ....... ................................................................ 639Localisation of enteropathogens in paraffin embedded tissue by immunoperoxidase KR PARSONS, AM WILSON, GA HALL, JC BRIDGER,N CHANTER, DJ REYNOLDS ........................................................................................... 645Hyperinsulinaemic hypoglycaemia due to chlorpropamide-induced nesidioblastosis G RAYMAN, M SANTO, F SALOMON, S ALMOG, FJPARADINAS, J PINKHAS, KW REYNOLDS, PH WISE ....... ................................................................... 651Necrosis of the pancreas in the haemolytic uraemic syndrome RA PRIMHAK, LS TAITZ, S VARIEND, DHK WEBB, A CSER .... ....... 655Platelet and coagulation factors in proliferative diabetic retinopathy DQ BORSEY, CV PROWSE, RS GRAY, J DAWES, K JAMES, RA ELTON,BF CLARKE ....................................................................................................... 659High colony stimulating activity in a patient with disseminated carcinoma and neutrophil leucocytosis HAW O'BRIEN, MA HORTON . 665Provision of leucocyte poor blood at the bedside ELIZABETH MaCNAMARA, SHEILA CLARKE, SR MCCANN ......... .. ............. 669Bacteraemia during prostatectomy and other transurethral operations: influence of timing of antibiotic administration DMMURPHY, L STASSEN, ME CARR, WA GILLESPIE, MT CAFFERKEY, FR FALKINER .................................................... 673Campylobacter biotyping scheme of epidemiological value FJ BOLTON, AV HOLT, DN HUTCHINSON .......... .. ............... 677Detection of Chlamydia trachomatis inclusions in McCoy and HeLa-229 cells: an alternative staining technique using toluidineblue NOORIA RS MOHAMMED, IRENE B HILLARY ....... .................................................................. 682Serum specific IgA antibody to Chlamydia trachomatis in patients with chlamydial infections detected by ELISA and animmunofluorescence test R CEVENINI, I SAROV, F RUMPIANESI, M DONATI, C MELEGA, C VARlOTr, M LA PLACA ....... .. ........... 686Estimation of IgG and IgM brucella antibodies in infected and non-infected persons by a radioimmune technique WG HEWITf, DJHPAYNE ........................................................................................................... 692Immunoglobulin and other proteins in the cerebrospinal fluid of patients with Alzheimer's disease HM CHAPEL, MM ESIRI, GKWILCOCK .......................................................................................................... 697y-glutamyl transferase activity in fetal serum, maternal serum, and amniotic fluid during gestation c MONIZ, KH NICOLAIDES, DKEYS, CH RODECK .................................................................................................. 700Colonic bicarbonate output as a test of disease activity in ulcerative colitis WEW ROEDIGER, MJ LAWSON, V KWOK, A KERR GRANT, PRPANNALL .......................................................................................................... 704Technical methodsSimple immunocytochemical staining procedure for lymphoid cell surface markers done on cell smears PAK-KWAN HUI, R JOYCE 708Fluorimetric method for measuring chemotaxis LATIKA SHAH, HE LARSON ................................................ 709Rapid identification of Clostridium difficile by direct detection of volatile organic acids from primary isolation media T MAKIN . 711Letters to the Editor .............................................................................................. 713Book reviews ................................................................................................. 716

No 7 JULY 1984

Review articleAlcohol induced liver disease KA FLEMING, JO'D MCGEE.............................. ................................ 721Production of human chorionic gonadotrophin by a hepatoblastoma resulting in precocious puberty R BEACH, P BETIS, M RADFORD,H MILLWARD-SADLER ............................................................................................... 734

on February 27, 2020 by guest. P

rotected by copyright.http://jcp.bm

j.com/

J Clin P

athol: first published as on 1 January 1984. Dow

nloaded from

Contents

Page

Immunocytochemical localisation of renin in nephroblastoma GBM LINDOP, S FLEMING, AAM GIBSON ..... .................... 738Changes in bone histoquantitative parameters and histochemical staining reactions for aluminium in a group of patients withchronic renal failure following a reduction in the aluminium concentration of the haemodialysis fluid J MCCLURE, NL FAZZALARI, RGFASSETT, PG PUGSLEY .............................................................................................. 743

Endoscopic screening for malignancy in the gastric remnant: the clinical significance of dysplasia in gastric mucosa GJAOFFERHAUS, J vd STADT, K HUIBREGTSE, GNJ TYTGAT..................................................... - 748Shape and texture analysis of liver cell nuclei in hepatomas by computer aided microscopy R JAGOE, C SOWTER, G SLAVIN ...... 755Hepatitis A, B, and non-A, non-B in Danish hospital nursing staff P SKINH0J, H VINTERBERG, J ALDERSHVILE, P KRYGFR .... .... 763Reed-Sternberg/lymphocyte rosette: lymphocyte subpopulations as defined by monoclonal antibodies CHRISTINE S MORRIS, AESTUART .76..........................................................................................................767Plasminogen activators in alcoholic cirrhosis: demonstration of increased tissue type and urokinase type activator NUALA A BOOTH,JUDITH A ANDERSON, B BENNETT ...................................................................................... 772Blood group Lewis phenotype on erythrocytes and in saliva in alcoholic pancreatitis and chronic liver disease L STIGENDAL, ROLSSON, L RYDBERG, BO E SAMUELSSON ........ ....................................................................... 778

Defective phagocytosis in insulin controlled diabetics: evidence for a reaction between glucose and opsonising proteins NJDAVIDSON, JM SOWDEN, J FLETCHER ........ ............... . ............................................................ 783Fibronectin as an opsonic regulator of monocyte phagocytosis AW SIMPSON, BJ BOUGHTON ................................. 787Impaired opsonophagocytosis of serotypes lb and II of group B streptococci as compared with serotypes Ia and III: role of thealternative pathway of complement in opsonisation of serotype III of group B streptococci P HINDOCHA, RUTH HILL, CBS WOOD,URMILA PATEL, G HUNT ............................................................................................. 790Detection of toxin production by Corynebacterium diphtheriae: results of a trial organised as part of the United Kingdom NationalExternal Microbiological Quality Assessment Scheme JJS SNELL, IV DEMELLO, PS GARDNER, W KWANTES, R BROOKS .... ........ 796An assessment of environmental contamination arising from the use of some automated equipment in microbiology GJ HARPER 800Comparison of the Vi indirect fluorescent antibody test with the Widal agglutination method in the serodiagnosis of typhoidfever NIVEDITA DOSHI, AG TAYLOR .................................................................................... 805Comparison of the sensitivity of microscopy and culture in the laboratory diagnosis of intestinal protozoal infection A MCMILLAN,GJC McNEILLAGE .............. ................................................................................... 809Sensitivity of detecting Chlamydia trachomatis elementary bodies in smears by use of a fluorescein labelled monoclonal antibody:comparison with conventional chlamydial isolation BRENDA J THOMAS, RT EVANS, DA HAWKINS, D TAYLOR-ROBINSON .... ........ 812Food borne infection by a Norwalk like virus (small round structured virus) T RIORDAN, J CRASKE, JEANNE L ROBERTS, A CURRY 817C reactive protein rapid assay techniques for monitoring resolution of infection in immunosuppressed patients RI HARRIS, PCWSTONE, AG HUDSON, J STUART ................ ......................................................................... 821Serum placental type alkaline phosphatase in cigarette smokers PJ MCLAUGHLIN, AM TWIST, CC EVANS, PM JOHNSON .... ........ 826Technical methodsOptimal use of the cationic polyelectrolyte poly-L-lysine in the preparation of cell monolayers for diagnostic cytopathology KCWAITS, OAN HUSAIN ................................................................................................ 829Semiautomated method for quantitative urine culture SG EDMONDSON, LJ ENRIGHT ........................................ 831Value of factor VIII related antigen as a means of demonstrating extramedullary megakaryopoiesis J CROCKER, PJ SMITH ...... 834Letters to the Editor.............................................................................................. 836

No 8 AUGUST 1984

Review articleGlycosylated haemoglobin: measurement and clinical use I PEACOCK .................................................... 841Proximal renal tubular function in myelomatosis: observations in the fourth Medical Research Council trial EH COOPER, MAFORBES, RA CROCKSON, ICM MACLENNAN .................. ......... .................................................. 852Plasma ionised calcium in preterm infants: comparison with adults PD MAYNE, JA JAMES, IC BARNES, IZ KOVAR .... ............ 859Early plasma protein and mineral changes after surgery: a two stage process MA MYERS, A FLECK, B SAMPSON, CM COLLEY, J BENT, GHALL ................................................... ......................... 862Maternal serum a,-antitrypsin concentrations in normotensive and hypertensive pregnancies M LEGGE, GB DUFF, HC POTTER, MMHOETJES ........................................................................................................... 867Haemorrheological effects of prostaglandin E, infusion in Raynaud's syndrome GS LUCAS, MH SIMMS, NM CALDWELL, SJCALEXANDER, J STUART ......... ................ ..................................................................... 870Platelet impedance aggregation in whole blood and its inhibition by antiplatelet drugs IJ MACKIE, R JONES, SJ MACHIN .... ....... 874Consumption of fibrinolytic proteins in menstrual fluid from women with normal menstrual blood loss SA CEDERHOLM-WILLIAMS,MCP REES, AC TURNBULL ......... ....................... ............................................................ 879Measurement of cross linked fibrin derivatives in plasma: an immunoassay using monoclonal antibodies AN WHITAKER, AJ ELMS, PPMASCI, PG BUNDESEN, DB RYLATT, AJ WEBBER, IH BUNCE .................................................................. 882Assessment of the value of a competitive protein binding radioassay of folic acid in the detection of folic acid deficiency BJ BAIN,SN WICKRAMASINGHE, GN BROOM, RA LITWINCZUK, J SIMS ................................................................. 888Distribution of laminin, fibronectin, and interstitial collagen type III in soft tissue tumours AJ D'ARDENNE, P KIRKPATRICK, BC SYKES 895An investigation of f3 enolase as a histological marker of rhabdomyosarcoma JANICE A ROYDS, S VARIEND, WR TIMPERLEY, CB TAYLOR 905Nature of non-B, non-T lymphomas, an immunohistological study on frozen tissues using monoclonal antibodies G PALLESEN, PCLBEVERLEY, EB LANE, M MADSEN, DY MASON, H STEIN ....... ........................... . .................................... 911Morphological and immunohistological changes in the skin in allogeneic bone marrow recipients JP SLOANE, JA THOMAS, SF IMRIE,DF EASTON, RL POWLES ............................................................................................. 919

on February 27, 2020 by guest. P

rotected by copyright.http://jcp.bm

j.com/

J Clin P

athol: first published as on 1 January 1984. Dow

nloaded from

Contents

Page

Amine and peptide hormone production by lung carcinoid: a clinicopathological and immunocytochemical study FT BOSMAN, ABRUTEL DE LA RIVIERE, RWM GIARD, AAJ VERHOFSTAD, G CRAMER-KNIJNENBURG .............................................. 931Comparison of a commercial ELISA system with restriction endonuclease analysis for typing herpes simplex virus KJ SNITH, CRASHLEY, JM DARVILLE, J HARBOUR, APCH ROOME.......................................................................... 937Clostridium perfringens type C causing necrotising enteritis WPJ SEVERIN, AA de la FUENTE, MF STRINGER ..... ................. 942Extragenital granuloma inguinale (Donovanosis) diagnosed in the United Kingdom: a clinical, histological, and electronmicroscopical study DV SPAGNOLO, PR COBURN, JJ CREAM, BS AZADIAN .................................................... 945Technical methodsCounterimmunoelectrophoresis in the diagnosis of whooping cough PC BORELAND, SH GILLESPIE ............................ 950Sample collection for determination of plasma fibronectin concentration PEARL TCY TOY, MARION E REID ..... ............... 951Advantages of fixed stored materials for immunoelectron microscopy, with special reference to the study of malignantlymphomas H AKATSUKA, K KITO, M SHAMOTO, T SUCHI ................................................................. 953Letters to the Editor .............................................................................................. 956Book reviews ................................................................................................. 959

No 9 SEPTEMBER 1984

Review articleClinical and biological significance of aneuploidy in human tumours ML FRIEDLANDER, DW HEDLEY, IW TAYLOR .... ........... 961Monoclonal antibody to cytokeratin for use in routine histopathology CAROL A MAKIN, LYNDA G BOBROW, WF BODMER .... ..... 975Epithelial membrane antigen in cells from the uterine cervix: immunocytochemical staining of cervical smears B VALKOVA, MGORMEROD, D MONCRIEFF, DV COLEMAN ................................................................................. 984Starch synovitis AJ FREEMONT, ML PORTER, I TOMLINSON, RB CLAGUE, MIV JAYSON ........................................... 990Combined external quality assessment of cytology and histology opinions: a pilot scheme for a cluster of five laboratories OANHUSAIN, E BLANCHE BUTLER, FP WOODFORD .............................................. . .............................. 993Campylobacter like organisms on the gastric mucosa: culture, histological, and serological studies DM JONES, AM LESSELLS, JOANELDRIDGE ......................................................................................................... 1002Detection of campylobacter by immunofluorescence in stools and rectal biopsies of patients with diarrhoea AB PRICE, JEAN MDOLBY, PR DUNSCOMBE, JENNIFER STIRLING ........ ....................... ............................................. 1007Sequential study of C reactive protein in neonatal septicaemia using a latex agglutination test P HINDOCHA, CA CAMPBELL, JDMGOULD, A WOJCIECHOWSKI, CBS WOOD ...................................................... ............................ 1014Value of serum C-reactive protein measurement in the management of bone marrow transplant recipients. Part I: early transplantperiod SA WALKER, TR ROGERS, PAMELA G RICHES, S WHITE, JR HOBBS .................................................... 1018Value of serum C-reactive protein measurement in the management of bone marrow transplant recipients. Part II: latepost-transplant period SA WALKER, PAMELA G RICHES, TR ROGERS, S WHITE, JR HOBBS ....................................... 1022C reactive protein concentrations in neonates: determination by a latex enhanced immunoassay C O'CALLAGHAN, P FRANKLIN, TSJELLIOTr, I DEVERILL, N RICHARDS, RJ POWELL ....... .................................................................... 1027Influence of glycaemic normalisation by an artificial pancreas on phagocytic and bactericidal functions of granulocytes in insulindependent diabetic patients H GIN, E BROTrIER, J AUBERTIN ............................................................. 1029Idiopathic acquired sideroblastic anaemia transforming to acute myelosclerosis AC BESTED, G CHENG, PH PINKERTON, 0 KASSIM, JSSENN ............................................................................................................. 052Simultaneous inheritance and expression of classical haemophilia A and type IIA von Willebrand's disease AC BEDDALL, SMENAYAT, CE WILLIAMS, PE SHORT, FGH HILL ......... ....... ....................................................... 1035Depressed antithrombin III biological activity in opiate addicts A CERIELLO, P DELLO RUSSO, F CURCIO, A TIRELLI, D GIUGLIANO 1040Platelet derived malonyldialdehyde production in patients with thalassaemia major AP JEWELL, RE MARCUS ..... ............. 1043Glomerular function and hyperuricaemia in sickle cell disease AG MORGAN, K DE CEULAER, GR SERJEANT ..... ................ 1046Albumin bound and a2-macroglobulin bound zinc concentrations in the sera of healthy adults JW FOOTE, HT DELVES .... ...... 1050Recurrent bacteriuria and primary biliary cirrhosis: ABO blood group, P, blood group, and secretor status ISOBEL J ROSENSTEIN,GR HAZLEHURST, AK BURROUGHS, 0 EPSTEIN, SHEILA SHERLOCK, W BRUMFITT ................................................. 1055Comparison of antibiotic susceptibility results obtained with Adatab and disc methods JJS SNELL, MVS DANVERS, PS GARDNER 1059Capnocytophaga ochracea infection: two cases and a review of the published work PM HAWKEY, H MALNICK, SAM GLOVER, N COOK, JAWATTS ........................................................................................................... 1066Technical methodsIsolation of Bordetella pertussis: benefits of using both Bordet-Gengou and charcoal agar media F AHMAD, MARGARET A CALDER 1071Microimmunofluorescence technique for detection of antibody to Mycoplasma genitalium PM FURR, D TAYLOR-ROBINSON ....... 1072Improved method for sequential study of an isolated glomerulus by scanning electron, transmission electron, and lightmicroscopy SB OR, WL YAU, HK NGAI ................................................................................. 1075Letters to the Editor .............................................................................................. 1077Book reviews ................................................................................................. 1079Notice.................................................................................................. 1080

No 10 OCTOBER 1984

Iliac bone histomorphometry in adults and children with osteogenesis imperfecta LG STE-MARIE, SA CHARHON, C EDOUARD, MCCHAPUY, PJ MEUNIER ............................................................................................... 1081Demonstration of carcinoembryonic antigen in bone marrow from patients with carcinoma A GRAY, R DOWNING, R HILL, RW PAYNE,CWO WINDSOR ..................................................................................................... 1090

on February 27, 2020 by guest. P

rotected by copyright.http://jcp.bm

j.com/

J Clin P

athol: first published as on 1 January 1984. Dow

nloaded from

ContentsPage

Primary brain trauma in non-accidental injury IM CALDER, I HILL, CL SCHOLTZ ............................................ 1095Histological appearances of intracranial biopsies obtained using the Cavitron ultrasonic surgical aspirator RAS BLACKIE, A GORDON . 1101Pancreatic endocrine tissue in benign mediastinal teratoma PJS DUNN .................................................. 1105Borderline or malignant ovarian tumour? A case report of decision making with morphometry SPA BAAK, G VAN DER LEY ..... 1110Immunohistochemical demonstration of leucocyte elastase in human tissues J CROCKER, RACHEL JENKINS, D BURNET .... ...... 1114Herpes simplex lymphadenitis: a case report and review of the published work M LAPSLEY, P KETTLE, JM SLOAN .... .......... 1119Plasmids in throat and genital isolates of meningococci CA ISON, CM BELLINGER, AA GLYNN ................................. 1123Mycoplasma pneumoniae protein involved in the antibody response in human infection SM RAISANEN, n SUNI, A VAHERI ....... 1129Evaluation of sealed containers for use in centrifuges by a dynamic microbiological test method GJ HARPER ..... ............ 1134Serum 12-microglobulin and C reactive protein concentrations in viral infections EH COOPER, MA FORBES, MH HAMBLING ....... 1140Parvovirus infection in a family associated with aplastic crisis in an affected sibling pair with hereditary spherocytosis DH GREEN, AJBELLINGHAM, MJ ANDERSON ....................................... 4................................................. 1144Recommendation for a selected method for the measurement of plasma viscosity International Committee for Standardization inHaematology ... ............................................................................................ 1147Immunological comparison between human and rat plasminogen activators in blood and the vessel wall A KJAELDGAARD, BLARSSON, B ASTEDT ................................................................................................ 1153Hospital blood bank laboratory data processing system IR CLARK, J PAREKH, MARGARET PETERS, IDO FREW, RN IBBOTSON ........ 1157Distribution and concentration of cyclosporin in human blood K ATKINSON, KATHRYN BRITrON, J BIGGS ..... .................. 1167Quantification of bands produced by isoelectric focusing using immunoperoxidase UH PALUCH, G KEIR, S MOYLE, EJ THOMPSON . . 1172Comparison of five commercial kits for the determination of glycosylated haemoglobin D NORCLIFFE, ELIZABETH M TURNER .... 1177Digitisers: their use in the entry of orders, urinalysis results, and isoenzyme interpretation in a clinical biochemistry computersystem JANE F LOUGHLIN, Jf TUCKERMAN, AR HENDERSON ............................................................... 1182

Technical methodsSingle incubation double esterase cytochemical reaction using a single coupling reagent DM SWIRSKY ..... .................. 1187Simple technique to identify haemosiderin in immunoperoxidase stained sections CAROLE D NICKOLS ..... .................. 1190Storage of skin biopsies at - 70'C for future fibroblast culture KJ FOWLER ...............................................1191Active site directed inhibitor used in the production of antibodies against urokinase SA CEDERHOLM-'WILLIAMS, JM MARSHALL, HCHISSIC .......................................................................................................... 1193Letters to the Editor .............................................................................................. 1195Book reviews ................................................................................................ 1197Notices................................................................................................ 1200

No 11 NOVEMBER 1984

Review artcleVulvar intraepithelial neoplasia and microinvasive carcinoma of the vulva CH BUCKLEY, EB BUTLER, H FOX ..... .............. 1201Effect of chemotherapy on the histological appearances of testicular teratoma metastatic to the lung: correlation with patientsurvival M MADDEN, P GOLDSTRAW, B CORRIN ....... ................................................................. 1212Use of antibodies to carcinoembryonic antigen and human milk fat globule to distinguish carcinoma, mesothelioma, and reactivemesothelium RJ MARSHALL, A HERBERT, SG BRAYE, DB JONES ............................................................ 1215A quantitative study of histiocytic reticulum cells in diffuse and follicular non-Hodgkin s lymphomas J CROCKER, RACHEL JENKINS 1222Histometric study of the localisation of lymphocyte subsets and accessory cells in human Mantoux reactions JH GIBBS, J FERGUSON,RA BROWN, KJA KENICER, RC POTTS, G COGHILL, J SWANSON BECK .......................................................... 1227Detection of S-100 labelled cells in nasopharyngeal carcinoma L LAURIOLA, F MICHETTI, S SENTINELLI, D COCCHIA .... ......... 1235Penetration of the left ventricular myocardium by benign peptic ulceration: two cases and a review of the published work cPORTEOUS, D WILLIAMS, A FOULIS, BA SUGDEN .......................................................................... 1239Traumatic subarachnoid haemorrhage: an alternative source GC COAST, DJ GEE ........................................... 1245Human mast cells detected by monoclonal antibodies EF RIMMER, C TURBERVILLE, MA HORTON .............................. 1249Adult Fanconi syndrome progressing to multiple myeloma RL SEWELL, MS DORREEN ...................................... 1256Bone marrow fibre content in acute myeloid leukaemia before and after treatment A ISLAM, D CATOVSKY, JM GOLDMAN, DAG GALTON 1259Physiological activation of plasminogen in full term newborn infants MM AL HILALI, BE GILLIVER ............................ 1264Relation between the mucosal flora and Paneth cell population of human jejunum and ileum MARGARET E ELMES, MR STANTON, CHLHOWELLS, GH LOWE ................................................................................................ 1268Mucosal flora of the small intestine and the effect of preoperative antibiotics MARGARET E ELMES, CHL HOWELLS, GH LOWE ..... 1272Immunological identification of Neisseria gonorrhoeae with monoclonal and polyclonal antibody coagglutination reagents HYOUNG, KATHERINE G REID .................................................................................. 1276

Postmortem radiographic, histological and bacteriological studies of terminal respiratory infections and other pulmonary lesions inhospital and non-hospital necropsies P PAAKKO, T S&RKIOJA, J HIRVONEN, T NURMI, R LAHTI, S SUTINEN ..... ................... 1282Antibiotic susceptibility and biochemical properties of Streptococcus faecalis strains reacting with both D and G antisera BR BIRCH,MAEVE GL KEANEY, LEELA A GANGULI ................................................................................. 1289

Comparison of a latex agglutination test with other serological tests for the measurement of antibodies to Toxoplasma gondii RAPAYNE, JM FRANCIS, W KWANTES ...................................................................................... 1293

Endocarditis caused by Rothia dentocariosa SA BROEREN, MM PEEL ...................................................... 1298Necrotising fasciitis caused by Vibrio vulnifScus ML WOO, WGD PATRICK, MTP SIMON, GL FRENCH .............................. 1301Immune deficiency due to adenosine deaminase and purine nucleoside phosphorylase deficiency: a simple diagnostic test JLMADDOCKS, SA AL-SAFI, G WILSON .................................................................................... 1305

on February 27, 2020 by guest. P

rotected by copyright.http://jcp.bm

j.com/

J Clin P

athol: first published as on 1 January 1984. Dow

nloaded from

Contents

Page

Technical methodsSerogrouping of Legionella pneumophila by double diffusion and counter immunoelectrophoresis MG HOLLIDAY, J BARKER 1308New medium for enhancing pigment production of group B streptococci S SUKROONGREUNG, C NILAKUL, S TUNnIMAVANICH, SSANTIWATANAKUL ................................................................................................ 1310Demonstration of normoblasts in tissue sections by means of an immunohistochemical technique for haemoglobin J CROCKER, OHBGYDE, RACHEL JENKINS.1312Letters to the Editor .............................................................................................. 1314Book reviews ................................................................................................. 1317Notices................................................................................................. 1320Some new titles ................................................................................................ 1320

No 12 DECEMBER 1984

Review articleSickle cell disease in Britain MILICA BkOZOVIC, ELIZABETH ANIONWU.1321Evaluation of a commercial radioassay for the simultaneous estimation of vitamin B12 and folate, with subsequent derivation of thenormal reference range E RANIOLO, G PHILLIPOU, G PALTRIDGE, RE SAGE.1327Cobalamin and folate binding proteins in human tumour tissue K SHEPPERD, DA BRADBURY, JM DAVIES, DR RYRIE.1336The platelet defect in acute myeloid leukaemia BE WOODCOCK, PC COOPER, PR BROWN, C PICKERING, DA WINFIELD, FE PRESTON 1339Immunoperoxidase detection of T and B cells in blood compared with conventional methods PK HUI, JWM LAWTON.1343Morphological heterogeneity in childhood B cell acute lymphoblastic leukaemia K AL-RUBEI PE ROSE, FGH HILL.1348Uptake and excretion of iron by healthy elderly subjects VALDA W BUNKER, MARGARET S LAWSON, BARBARA E CLAYON.1353Increased ammoniagenesis and the renal tubular effects of potassium depletion DStJ O'REILLY.1358Epithelial markers in prostatic, bladder, and colorectal cancer: an immunoperoxidase study of epithelial membrane antigen,carcinoembryonic antigen, and prostatic acid phosphatase EADIE HEYDERMAN, BRENDA ME BROWN, TC RICHARDSON.1363Histological diagnosis of carcinoma of the parathyroid gland JF SMITH, RRH COOMBS.1370Actinomyces odontolyticus isolated from the female genital tract RG MITCHELL, MR CROW.1379Infective endocarditis caused by Kingella denitrificans RA SWANN, B HOLMES.1384Serotyping of Acinetobacter calcoaceuicus BC DAS, GAJ AYLIFFE.1388Rapid method for detecting ,B-lactamase producing bacteria in clinical specimens I BROOK, AE GOBER.1392Identification of Brevibacterium from clinical sources DG PITCHER, H MALNICK.1395Ultrastructural demonstration of retrovirus antigens with immuno-gold staining in prodromal acquired immune deficiencysyndrome ww FEREMANS, R MENU, M GOLDMAN, L SCHANDENE, D PORTETELLE, Y CLEUTER, J FLAMENT, P DUSTIN, J WYBRAN, A BURNY. 1399Rapid detection of enteric adenovirus and rotavirus: a simple method using polyacrylamine gel electrophoresis RB MOOSAI, MJCARTER, CR MADELEY ..1404Technical methodsControl c*xaid nitric acid decalcification WHB MAWHINNEY, E RICHARDSON, AJ MALCOLM.1409Method for the morphometric analysis of arterial structure J LOWE.1413Letters to the Editor .............................................................................................. 1415Book reviews....... 1417

on February 27, 2020 by guest. P

rotected by copyright.http://jcp.bm

j.com/

J Clin P

athol: first published as on 1 January 1984. Dow

nloaded from