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www.ewalt.org January 22 nd - 24 th , 2015 HUMANITAS CONGRESS CENTRE - MILAN, ITALY

January 22 - 24 , 2015 - Ewalt8:15 am Welcome Addresses G. Torzilli IMAGING FOR HCC Chairman: L. Balzarini 8:30 am Advances in imaging modalities for HCC O. Matsui THERAPEUTIC GUIDELINES

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Page 1: January 22 - 24 , 2015 - Ewalt8:15 am Welcome Addresses G. Torzilli IMAGING FOR HCC Chairman: L. Balzarini 8:30 am Advances in imaging modalities for HCC O. Matsui THERAPEUTIC GUIDELINES

www.ewalt.orgJanuary 22nd - 24th, 2015HUMANITAS CONGRESS CENTRE - MILAN, ITALY

Programma EWALT+session___Layout 1 19/01/15 12:02 Pagina 1

Page 2: January 22 - 24 , 2015 - Ewalt8:15 am Welcome Addresses G. Torzilli IMAGING FOR HCC Chairman: L. Balzarini 8:30 am Advances in imaging modalities for HCC O. Matsui THERAPEUTIC GUIDELINES

Dear Colleagues,It is my great pleasure to welcome all of you in Milano for the 1st edition of the International Meeting of the Easternand Western Association on Liver Tumors. An Association and a Meeting which follow the more than 15 years traditionof the HCC Eastern & Western Experiences Meetings which started in Paris in 1998 and concluded in Tokyo in 2013.They were biennial appointments which trapped the International Scientific Community somewhere in the world for2-3 days debating on HCC and the therapeutical solution for its control: Paris, Tokyo, Lodi (Italy), Hong Kong, Houston,Seoul, Paris and Tokyo again, where the places which hosted this successful initiative. Almost each of those eventsresulted in prestigious monograph, which summarized the highlights of the respective meetings. Then Hepatogastroenterology twice, Liver Transplantation, Annals of Surgical Oncology, Journal of HBP Sciences,and Liver Cancer hosted the highlights of the meetings in Paris, Tokyo, Lodi, Houston, Seoul and Tokyo, respectively.This success, the growing therapeutical offer of medical oncology, interventional radiology, radiotherapy ecc… otherthan that of both resective and transplant surgery, for HCC but also for other liver tumors have induced the foundersof the HCC Eastern & Western meeting to shift to Meetings dealing with the whole spectrum of liver tumors. In that,of course, the original aims of representing a moment of debate on practical issues comparing different perspectivein looking at the same problem from the Eastern rather than the Western side of the world will remain solid bases. The recently indexed journal Liver Cancer will be officially our scientific output maintaining the tradition and effortof having something which will traduce words and thinking occurred in prestigious and dense meetings in writtenand permanent documents available for the entire scientific community worldwide. A new challenge, which I havethe honor together with my team, to inaugurate herein at the Humanitas Research Hospital and Humanitas University.Passion, quality, and endurance of the friends who start with me this renewed adventure and of all of you, will certainlyprovide for now and the future valuable contribution in finding new solution for relieving and curing all those patientscarrier of a liver tumor in any corner of the world.

My warmest welcome to Milano and my best wishes for a profitable, and enjoyable stay with us.

Guido Torzilli, MD, PhD, FACS

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Page 3: January 22 - 24 , 2015 - Ewalt8:15 am Welcome Addresses G. Torzilli IMAGING FOR HCC Chairman: L. Balzarini 8:30 am Advances in imaging modalities for HCC O. Matsui THERAPEUTIC GUIDELINES

REGISTRATION

INTRODUCTIONLECTURE

9:00am -10:00 am

ROOM FSESSION 9

oral presentations9:00 am - 10:00 am

ROOM FSESSION 5

oral presentations10:30 am - 11:30 am

ROOM FSESSION 10

video presentations10:30 am - 11:30 am

ROOM F SESSION 1

oral presentations11:30 am - 12:30 pm

ROOM FLUNCHEON SEMINAR

ESAOTE12:30 pm - 1:30 pm

ROOM FSESSION 6

video presentations2:00 pm - 3:00 pm

ROOM F SESSION 7

oral presentations3:00 pm - 4:00 pm

ROOM FSESSION 3

video presentations2:30 pm - 3:30 pm

ROOM FSESSION 8

mini oral presentations4:00 pm - 5:00 pm

ROOM FSESSION 4mini oral

presentations5:00 pm - 6:00 pm

ROOM E PUSHING THE LIMITS

BREAKING NEWS2:00 pm - 4:00 pm

ROOM FSESSION 2

oral presentations1:30 pm - 2:30 pm

ROOM EWHICH ABLATION1:30 pm - 2:30 pm

ROOM EIMAGING FOR CLM8:30 am - 8:45 am

THE STATE OF THE ART8:45 am - 9:45 am

ROOM ECHEMOTHERAPY AND

SURGERY10:30 am - 12:15 pm

ROOM EMASTER'S TALK

FROM ULTRASOUND TO SURGERY11:00 am - 11:30 am

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ROOM E Master Video Session:

SKIN AND ORGAN TARGETED MINI-INVASIVITY5:40 pm - 6:40 pm

EXH

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GALA DINNER

ROOM EBEST ORAL PRESENTATIONS

3:45 pm - 5:00 pm

Coffee break

Coffee break

ROOM ENEW PERSPECTIVES4:15 pm - 5:30 pm

EXH

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ROOM E MASTER'S TALK

FROM PIGGYBACK TO HANGING: THE FRENCH REVOLUTION

9:45 am - 10:15

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Coffee break

ROOM E BEST ORAL PRESENTATIONS

12:15 pm - 1:00 pm

ROOM ELUNCHEON SEMINAR

Hitachi-Aloka1:00 pm - 2:00 pm

ROOM ETHERAPEUTIC GUIDELINES

BREAKING NEWS8:45 am - 10:30 am

ROOM EIMAGING FOR HCC 8:30 am - 8:45 am

Conclusions and take-home

messages4:00 pm - 5:00 pm

Ultra

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LIVE SURGERY

LIVE DEMO FROM THE OPERATORY

ROOM

10:00 am - 4:00 pm

ROOM ESURGEONS AT WORK

5:00 pm - 6:40 pm

WELCOME RECEPTION

5:00 pm - 6:30 pm

ROOM EINTRA-ARTERIAL TECHNIQUES

2:30 pm -3:30 pm

ROOM ELIVER TRANSPLANTATION FOR

HCC11:30 am - 12:30 pm

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HCC D

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Coffee break

REGISTRATION

ROOM ELUNCHEON SEMINAR

SIRTeX12:30 pm - 1:30 pm

EXH

IBIT

ION

Coffee break

ROOM ETREATMENT FOR NET

METASTASES10:40 am - 12:00 pm

END OF THE CONGRESS

ROOM ECHOLANGIOCARCINOMA

8:30 am - 8:45 am

ROOM ETREATMENT OF

CHOLANGIOCARCINOMA8:45 am - 10:20 am

EWALT 2015JANUARY 21, 2015

WednesdayJANUARY 22, 2015

ThursdayJANUARY 23, 2015

FridayJANUARY 24, 2015

Saturday

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Page 4: January 22 - 24 , 2015 - Ewalt8:15 am Welcome Addresses G. Torzilli IMAGING FOR HCC Chairman: L. Balzarini 8:30 am Advances in imaging modalities for HCC O. Matsui THERAPEUTIC GUIDELINES

8:15 am Welcome Addresses G. Torzilli

IMAGING FOR HCC Chairman: L. Balzarini8:30 am Advances in imaging modalities for HCC O. Matsui

THERAPEUTIC GUIDELINES Chairmen: M. Colombo, JN. Vauthey8:45 am The Western point of view F. Trevisani9:00 am The Eastern point of view M. Kudo9:15 am Surgery for HCC in the real world G. Torzilli

9:30 am Controversies on the medical treatment G.K. Abou-Alfa9:45 am The role of interventional oncology R. Lencioni

10:00 am Discussion

Breaking news

10:15 am Is it the time for a second line systemic treatment? L. Rimassa

10:30 am Coffee Break

11:00 am MASTER'S TALK Chairman: G. TorzilliFROM ULTRASOUND TO SURGERY M. Makuuchi

HCC DAY THURSDAY JANUARY 22nd, 2015

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Page 5: January 22 - 24 , 2015 - Ewalt8:15 am Welcome Addresses G. Torzilli IMAGING FOR HCC Chairman: L. Balzarini 8:30 am Advances in imaging modalities for HCC O. Matsui THERAPEUTIC GUIDELINES

HCC DAY

LIVER TRANSPLANTATION FOR HCC Chairmen: J. Belghiti, L. De Carlis11:30 am Liver transplantation for HCC: the Western perspective A. Pinna11:45 am Liver transplantation for HCC: the Eastern perspective N. Kokudo

12:00 pm Liver transplantation for HCC: benefit as endpoint U. Cillo 12:15 pm Discussion

12:30 pm LUNCHEON SEMINAR

Luncheon seminar-1SIR-Spheres® microspheres (Y-90 resin microspheres) – a new paradigm for inoperable liver tumours SIRTeX

Luncheon seminar-2Interventional radiologists and surgeons allied against liver tumors with the aid of ultrasound ESAOTE

WHICH ABLATION Chairmen: D. Elias, M. Scorsetti1:30 pm Ablation of HCC: the Eastern perspective S. Shiina1:45 pm Ablation of HCC: the Western perspective L. Solbiati

2:00 pm Any role for Radiotherapy? L. Dawson2:15 pm Discussion

THURSDAY JANUARY 22nd, 2015

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Page 6: January 22 - 24 , 2015 - Ewalt8:15 am Welcome Addresses G. Torzilli IMAGING FOR HCC Chairman: L. Balzarini 8:30 am Advances in imaging modalities for HCC O. Matsui THERAPEUTIC GUIDELINES

INTRA-ARTERIAL TECHNIQUES Chairmen: G. Ettorre, V. Vilgrain2:30 pm TACE & TAE T. Helmberger2:45 pm Predictors of response: the Western perspective M. Roncalli3:00 pm Predictors of response: the Eastern perspective Y.N. Park3:15 pm Discussion

3:30 pm Coffee Break

BEST ORAL PRESENTATIONS Chairmen: A. Ferrero, R. Pellicci

3:45 pm An algorithm based on liver stiffness and model-for end-stage liver disease outline liver failure risk after hepatectomy of hepatocellular carcinoma

A. Cucchetti, ItalyM. Cescon | A. Colecchia | G. Ercolani | M. Ravaioli | M.Del Gaudio | G. Marasco | D. Festi | A. D. Pinna

Clinical outcome of repeat hepatectomy for recurrent hepatocellular carcinoma T. Matsumoto, Japan

K. Kubota

Assessment of the importance of pre-transplant alpha-fetoprotein dynamics in liver transplantation for hepatocellular cancer M. Grat, Poland

M. Grąt | M. Krasnodębski | W. Patkowski | K. M. Wronka | Ł.Masior | J. Stypułkowski | K. Grąt | M. Krawczyk

Usefulness of CE-IOUS using perflubutane in patients with liver tumors: results obtained from two prospective clinical studies J. Arita, Japan

S. Yamamoto | N. Akamatsu | J. Kaneko | Y. Sakamoto | K. Hasegawa | Y. Sugawara | A. Saiura | N. Kokudo

HCC DAY THURSDAY JANUARY 22nd, 2015

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Page 7: January 22 - 24 , 2015 - Ewalt8:15 am Welcome Addresses G. Torzilli IMAGING FOR HCC Chairman: L. Balzarini 8:30 am Advances in imaging modalities for HCC O. Matsui THERAPEUTIC GUIDELINES

SURGEONS AT WORK Chairmen: J. Lerut, E. De Santibanes5:00 pm Preoperative and intraoperative navigation technology I. Endo5:15 pm Fluorescent image-guided liver surgery N. Kokudo

5:30 pm Selection criteria for safe hepatectomy for HCC: the Western perspective M. Donadon

5:45 pm Laparoscopic liver resection for HCC: the Western perspective D. Cherqui

6:00 pm Laparoscopic liver resection for HCC: the Eastern perspective G. Honda

Breaking news

6:15 pm IGOMILS L. Aldrighetti6:20 pm Discussion6:40 pm End of the day

THURSDAY JANUARY 22nd, 2015HCC DAY

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Page 8: January 22 - 24 , 2015 - Ewalt8:15 am Welcome Addresses G. Torzilli IMAGING FOR HCC Chairman: L. Balzarini 8:30 am Advances in imaging modalities for HCC O. Matsui THERAPEUTIC GUIDELINES

SESSION 1 | oral presentations THURSDAY JANUARY 22nd, 2015 11:30 am - 12:30 pmChairmen: H.S. Han, M. Donadon

1Liver resection of metabolic syndrome related HCC: a comparative study with viral and alcoholic HCC

S. Conci, ItalyA. Ruzzenente | M. De Angelis | S. Conci | F. Bagante | A. Valdegamberi | F. Bertuzzo | G. Mantovani | C. Iacono | A. Guglielmi

The ITALICA staging system for patients with HCC: a multicenter cohort study A. Vitale, ItalyU. Cillo | F. Trevisani | T.I. Huo | Y.H. Lee | F. Farinati

Hemodynamic differences in the very early phase of hepatocellular carcinoma using contrast-enhanced ultrasonography A. Saito, Japan

S. Katagiri | M. Yamamoto | T. Morizane

Management of hepatocellular carcinoma with tumor thrombi extending to right heart: proposal of two-stage hepatectomy C. Wu, China

S.B. Cheng | S.R. Hsieh | J.H. Shen

Portal vein embolization for hepatocellular carcinoma K. Kubota, JapanM. Kato | T. Matsumoto

Multicentric vs. metastatic hepatocellular carcinoma: pathological concern or different clinical subtypes?M. Cimino, Italy

M. Donadon | L. Di Tommaso | L. Viganò | D. Del Fabbro | F. Procopio | M. Roncalli | G. Torzilli

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Page 9: January 22 - 24 , 2015 - Ewalt8:15 am Welcome Addresses G. Torzilli IMAGING FOR HCC Chairman: L. Balzarini 8:30 am Advances in imaging modalities for HCC O. Matsui THERAPEUTIC GUIDELINES

SESSION 2 | oral presentations THURSDAY JANUARY 22nd, 2015 1:30 pm - 2:30 pmChairmen: H.J. Kim, G. Ercolani

2The challenge of inoperable Hepatocellular Carcinoma: results of a single-institutional experience on Stereotactic Body Radiation Therapy T. Comito, Italy

C. Franzese | E. Clerici | A. Tozzi | P. Navarria | G.R. D'Agostino | E. Villa | F. De Rose | A. Ascolese | C. Iftode | S. Tomatis | P. Mancosu | F. Lobefalo | A. Gaudino | V. Palumbo | M. Scorsetti

Outcome of High intensity focused ultrasound ablation vs RFA with bile duct cooling for HCC located near the bile duct in patients with cirrhosis. A case-matched comparative study T. Cheung, China

C. Mau Lo | T. Yau | S. Tat Fan

Laparoscopic anatomical hepatectomy for hepatocellular carcinoma T. Ryu, JapanG. Honda | M. Kurata | S. Kobayashi | K. Sakamoto | M. Honjo

Is anatomical liver resection useful for improving prognosis of patients with hepatocellular carcinoma?K. Kubota, Japan

T. Matsumoto Rapid fibrosis and significant histologic recurrence of hepatitis post liver transplant is associated with higher tumor recurrence rates post liver transplant in Hepatocellular carcinomas associated with Hepatitis C virus related liver disease B. Vasavada, Taiwan

C.L. Chan | K. Julka

Early identification of patients at increased risk for hepatic insufficiency and complications after major hepatectomy. M. De Bellis, Italy

M. Iaria | G. Pedrazzi | E. Bertocchi | R. Dalla Valle

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Page 10: January 22 - 24 , 2015 - Ewalt8:15 am Welcome Addresses G. Torzilli IMAGING FOR HCC Chairman: L. Balzarini 8:30 am Advances in imaging modalities for HCC O. Matsui THERAPEUTIC GUIDELINES

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SESSION 3 | video presentations THURSDAY JANUARY 22nd, 2015 2:30 pm - 3:30 pmChairmen: R. Santambrogio, D. Del Fabbro

3Right hepatectomy by anterior approach and hanging manouver for giant fibrolamellar HCC A. Belli, Italy

C. Fantini | A. D'Agostino | G. Belli

A strategy to treat huge hepatocellular carcinoma with the inferior vena cava and portal vein invasion in a young hepatitis B virus-infected adult K.C. Hung, Taiwan

Y.S. Chen | P.M. Hsieh | L.F. Lu | P.L. Sun | C.W. Lin | P.H. Lee | C.H. Hung

Single Incision Laparoscopic Partial Hepatectomy F. Cannizzo, USAJ.E. Meyer | J.R. Romanelli | R.B. Arenas

The Lateral approach liver hanging maneuver in laparoscopic anatomical liver resections J. H. Kim, South KoreaJ.H. Kim | J.W. Choi

Robotic atypical liver resection of segments 1 and 4a S. Amore Bonapasta, ItalyL. Moraldi | F. Perna | I. Bartolini | F. Guerra | S. Aldrovandi | C. Linari

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Page 11: January 22 - 24 , 2015 - Ewalt8:15 am Welcome Addresses G. Torzilli IMAGING FOR HCC Chairman: L. Balzarini 8:30 am Advances in imaging modalities for HCC O. Matsui THERAPEUTIC GUIDELINES

SESSION 4 | mini oral presentations THURSDAY JANUARY 22nd, 2015 5:00 pm - 6:00 pmChairmen: D. Ribero, D. Fuks

Management of recurrent HCC after curative resection: a retrospective study of 269 patients S. Conci, ItalyA. Ruzzenente | A. Valdegamberi | M. Fontana | F. Bertuzzo | M. Piccino | G. Mantovani | C. Iacono | A. Guglielmi

What has changed in clinical features at diagnosis, treatment and survival of hepatocellular carcinoma in the last years: a population-based study in a Southern-Europe country S. Molfino, Italy

F. Donato | E. Raffetti | G.L. Baiocchi | R.M. Limina | G. Caccamo | F. Gheza | N. Portolani

Microinvasive intraoperative ultrasound pattern in predicting outcomes for single small HCC R. Santambrogio, ItalyM. Barabino | M. Costa | S. Camelio | M. Virdis | E. Opocher

Combined Radiofrequency Ablation and Sorafenib in the treatment of advanced Hepatocellular CarcinomaM. Kuang, China

C. Jiang | B. Liu | X. Xie | M. Lin | Y. Wang | M. Lu

Local Recurrence after Radiofrequency Ablation of Hepatocellular Carcinoma: Treatment choice and Survival AnalysisM. Kuang, China

B. Liu | M. Lin | W. Hu | S. Shen | C. Jiang | D. Li

Critical aspects in the management of HCC: indications to hepatic resection according to BCLC systemF. Romano, Italy

S. Nespoli | M. Garancini | F. Uggeri | L. Nespoli | L. Degrate | L. Gianotti

Is the Barcelona Clinic Liver Cancer classification still useful as indication to surgical resection in patients affected by hepatocellular carcinoma? A retrospective analysis from a Northern-Italy tertiary referral HPB center

N. De Ruvo, ItalyV. Serra | R. Ballarin | N. Cautero | G. Tarantino | F. Di Benedetto

Salvage transplantation for post-resection recurrence of hepatocellular carcinoma associated with hepatitis C virus aetiology: a feasible strategy? B. Vasavada, Taiwan

C.L. Chan | K. Julka | A. Kormoswoski

Prior Trans-arterial chemoembolization: a protective factor against rapid HCV recurrence after liver transplant in patients with HCV with HCC? A retrospective analysis B. Vasavada, Taiwan

C.L. Chan | K. Julka

Survival and prognostic factors after hepatectomy for hepato-cholangiocarcinoma: a case-match analysis with classic hepatocellular carcinoma and mass-forming cholangiocarcinoma A. Gatti, Italy

G. Costa | M. Donadon | L. Di Tommaso | L. Viganò | M. Cimino | D. Del Fabbro | F. Procopio | M. Roncalli | G. Torzilli

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Page 12: January 22 - 24 , 2015 - Ewalt8:15 am Welcome Addresses G. Torzilli IMAGING FOR HCC Chairman: L. Balzarini 8:30 am Advances in imaging modalities for HCC O. Matsui THERAPEUTIC GUIDELINES

www.hitachi-medical-systems.eu

Now available with the new robotic transducer L43K, supporting safe & precise surgeries

COME AND EXPERIENCE IT FOR YOURSELF!FOR YOURSELF!EXPERIENCE IT COME AND

FOR YOURSELF!EXPERIENCE IT COME AND

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Page 13: January 22 - 24 , 2015 - Ewalt8:15 am Welcome Addresses G. Torzilli IMAGING FOR HCC Chairman: L. Balzarini 8:30 am Advances in imaging modalities for HCC O. Matsui THERAPEUTIC GUIDELINES

METS DAY FRIDAY JANUARY 23rd, 2015

IMAGING FOR CLM Chairman: O. Matsui8:30 am Preoperative staging: the role of CT, MRI and PET-CT V. Vilgrain

THE STATE OF THE ART Chairmen: A. Falcone, W. Jarnagin8:45 am Should every resectable CLM be resected? Present indications and limits N. Kokudo9:00 am Neoadjuvant chemotherapy in resectable patients:

The West experience G. FolprechtThe East experience M. Unno

9:20 am Multidisciplinarity in surgical oncology: the ESSO perspective G. Poston9:35 am Discussion

9:45 am MASTER'S TALK Chairman: M. MakuuchiFROM PIGGYBACK TO HANGING: THE FRENCH REVOLUTION J. Belghiti

10:15 am Coffee Break

CHEMOTHERAPY AND SURGERY Chairmen: G. Folprecht, R. Adam10:30 am Conversion chemotherapy: which regimen to achieve resectability? A. Falcone10:45 am Surgery in initially unresectable patients F. Giuliante11:00 am Chemotherapy-related liver injury: prediction and impact O. Soubrane11:15 am Evaluation and prognosis of patients undergoing resection:

the emerging role of RAS mutations JN. Vauthey

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Page 14: January 22 - 24 , 2015 - Ewalt8:15 am Welcome Addresses G. Torzilli IMAGING FOR HCC Chairman: L. Balzarini 8:30 am Advances in imaging modalities for HCC O. Matsui THERAPEUTIC GUIDELINES

11:30 am Disappearing colorectal metastases after chemotherapy W. Jarnagin11:45 am The role of intra-arterial chemotherapy D. Goere

12:00 pm Discussion

BEST ORAL PRESENTATIONS Chairmen: E. Rosso, R. Santambrogio

12:15 pm Minor-but-Complex Hepatic Resection: a new approach for surgical management of hepatic outflow at the caval confluence to spare liver parenchyma in the treatment of colorectal metastasis L. Urbani, Italy

G. Masi | M. Puccini | R. Balestri | A. Marioni | F. Sidoti | E. Rossi | M. Franceschi | V. Prosperi |C. Vivaldi | P. Boraschi | A. Falcone | P. Buccianti

Outcome of ALPPS procedure by the anterior approach A. Chan, ChinaR. Poon | J. Dai | C. Tan To | K. Chok | L. Chung Mau

The survival benefit of lymphadenectomy in patients with intrahepaticcholangiocarcinoma undergoing hepatic resection A. Vitale, Italy

G. Zanus | E. Gringeri | U. Cillo

Prognostic relevance of lymph node status in resected patients with hilar cholangiocarcinoma: results of an italian multicenter analysis F. Ardito, Italy

A. Ferrero | L. Aldrighetti | F. Calise | S. M. Giulini | A. Guglielmi | E. Jovine | A. Pinna | G. Nuzzo | F. Giuliante

FRIDAY JANUARY 23rd, 2015METS DAY

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1:00 pm LUNCHEON SEMINARLuncheon seminar-3: New ultrasound technologies for hepatic surgeons Hitachi-Aloka

PUSHING THE LIMITS Chairmen: N. Kokudo, A. Pinna2:00 pm Two-stage hepatectomy R. Adam2:15 pm One-stage hepatectomy G. Torzilli

2:30 pm ALPPS E. De Santibanes2:45 pm Surgical margin R0 vs R1:

The pathologist L. Rubbia-BrandtThe surgeon L. Viganò

3:05 pm Reverse strategy for synchronous metastases P. Majno3:20 pm Discussion

Breaking news

3:35 pm Italian registry of ALPPS E. Jovine3:45 pm Results of laparoscopic two stage hepatectomies D. Fuks3:55 pm Discussion

4:00 pm Coffee Break

FRIDAY JANUARY 23rd, 2015METS DAY

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NEW PERSPECTIVES Chairmen: P. Majno, A. Chiti4:15 pm Peritoneal carcinomatosis: still a contraindication? D. Elias

4:30 pm Interstitial treatments: what's new about RF and MW ablation? L. Solbiati4:45 pm Radioembolization F. Orsi5:00 pm Liver transplantation for CLM: myth or reality? J. Lerut5:15 pm Radiotherapy M. Scorsetti

5:30 pm Discussion

Master Video Session:SKIN AND ORGAN TARGETED MINI-INVASIVITY Chairmen: F. Calise, D. Cherqui

5:40 pm Laparoscopic liver resection H.S. Han5:50 pm Laparoscopic liver resection G. Belli6:00 pm Laparoscopic liver resection H. Kaneko6:10 pm Laparoscopic liver resection H.J. Kim6:20 pm Ultrasound-guided conservative surgery F. Procopio6:30 pm Discussion6:40 pm End of the day

FRIDAY JANUARY 23rd, 2015METS DAY

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SESSION 5 | oral presentations FRIDAY JANUARY 23rd, 2015 10:30 am - 11:30 amChairmen: H. Kaneko, L. Aldrighetti

5Impact of advanced age on the outcomes in patients undergoing liver resection for colorectal metastases: our experience S. Vaccari, Italy

E. De Raffelei | M. Mirarchii | B. Pirrerai | F. Leccei | B. Dalla Viai | D. Cuicchii | R. Bellusci | A. Cavallari | B. Cola

Laparoscopic management of colorectal cancer with synchronous liver metastases: a single center experience S. Berti, Italy

E. Francone | C. Sagnelli | A. Ferrarese | C. Feleppa | E. Falco

Single-center experience in the surgical treatment of fastric, gastro-esophageal junction and esophageal cancer liver metastases H. Alexandrino, Portugal

R. Martins | L. Ferreira | M. Serôdio | M. Martins | J. Guilherme Tralhão | F. Castro e Sousa

Liver resection for colorectal metastases in older adults: a paired-matched analysis N. De Ruvo, ItalyR. Ballarin | N. Cautero | V. Serra | G. Tarantino | F. Di Benedetto

Prospective diagnostic test accuracy comparison of Computed Tomographyduring Arterial Portography (CTAP) and Primovist MRI in the pre-operative assessmentof colorectal cancer liver metastases J. S. Bagia, Australia

A. Teixeira-Pinto | A. Chai | R. Chou | C. Chu | J. Rouse | E. Sinclair | L. Vonthethoff

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Simultaneous laparoscopic right hepatectomy combined with extended laparoscopic right colectomyfor hepatic flexure cancer plus synchronous liver metastases. N. Belev, Bulgaria

N. Shopov | P. Rusev | M. Slavchev | K. Staneva | G. Dgarov

Laparoscopic sigmoid resection combined with left liver lobectomy extended to segment IVa for sigmoid cancer and synchronous liver metastasis N. Belev, Bulgaria

N. Shopov, P. Rusev, P. Krastev, S. Popov

Use of real-time virtual sonography in liver surgery S. Satou, JapanY. Beck | N. Kokudo

Evolution of laparoscopic right hepatectomy F. Ratti, ItalyL. Aldrighetti

Laparoscopic approach for left lateral sectionectomy is feasible, safe and efficient even as a “rescue procedure” F. Ratti, Italy

L. Aldrighetti

SESSION 6 | video presentations FRIDAY JANUARY 23rd, 2015 2:00 pm - 3:00 pmChairmen: G. Ettorre, D. Del Fabbro

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SESSION 7 | oral presentations FRIDAY JANUARY 23rd, 2015 3:00 pm - 4:00 pmChairmen: F. Giuliante, K. Kubota

7Therapeutic strategy for patients with disappearing colorectal liver metastases: experience of an Italian high volume center A. Coppola, Italy

E. Panettieri | F. Ardito | C. Mele | A. M. De Rose | N. Silvestrini | M. Vellone | F. Giuliante

Neoadjuvant folfiri+bevacizumab in patients with resectable liver metastases from colo-rectal cancer: results from a phase 2 trial and comparative analysis of early PET/CT scan vs RECIST criteria in predicting outcome A. Belli, Italy

M. Leongito | R. Palaia | V. Albino | G. Nasti | S. Lastoria | G. Romano | F. Izzo

Stereotactic Body Radiation Therapy for inoperable liver metastases from colorectal cancer: results of a phase II trial C. Franzese, Italy

T. Comito | E. Clerici | A. Tozzi | P. Navarria | G.R. D'Agostino | E. Villa | F.De Rose | A. Ascolese | C. Iftode | S. Tomatis | G. Reggiori | P. Mancosu | A. Stravato | M. Scorsetti

Survival impact of R1 resection for colorectal liver metastasis K. Sakamoto, JapanGoro Honda, Masanao Kurata, Shin Kobayashi, Masahiko Honjo, Tomoki Ryu

Synchronous surgery for colorectal cancer and liver metastases: laparoscopic colorectal resection improves short term outcome. A comparative study F. Ratti, Italy

M. Catena | S. Di Palo | C. Staudacher | L. Aldrighetti

Strategies to increase resectability of patients with Colorectal Liver Metastases: A multi-center case-match analysis of ALPPS versus conventional Two-Stage Hepatectomy F. Ratti, Italy

E. Schadde | M. Masetti | M. Massani | M. Zanello | M. Serenari | F. Cipriani, L. Bonariol | N. Bassi | L. Aldrighetti | E. Jovine

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SSESSION 8 | mini oral presentations FRIDAY JANUARY 23rd, 2015 4:00 pm - 5:00 pmChairmen: E. Rosso, L. Viganò

8Repeated hepatectomy for liver tumours: is it safe? S. Vaccari, Italy

E. De Raffele | M. Mirarchi | B. Pirrera | F. Lecce | B. Dalla Via|D. Cuicchi | R. Bellusci | A. Cavallari | B. Cola

Does the aging affect the short-term outcomes of patients undergoing liver resection? A single tertiary referral centre experience S. Conci, Italy

G. Mantovani | A. Ruzzenente | A. Ciangherotti | F. Bagante | T. Campagnaro | A. Valdegamberi | C. Iacono | A. Guglielmi

Establishing a hepatobiliary center in the middle of an economic crisis G. Tsoulfas, GreeceA. Tooulias | B. Tsiantzi | A. Vlaxodimos | A. Fandakis | V. Papagiannis | G. Marakis | G. Tsoulfas

Single Port Laparoscopic Liver Resection: a single institution case series with extended follow-up F. Cannizzo, USAL. L. Davis | J. R. Romanelli | R. B. Arenas

Consecutive successful ALPPS in 2 years without reoperation and mortality J. Li, GermanyF. Ewald | E. Achilles | L. Fischer | B. Nashan

Comparative analysis of left versus right sided resection in patients undergoing liver surgery for Klatskin tumor: can lesion side be considered a prognostic factor? F. Ratti, Italy

F. Cipriani | G. Piozzi | M. Catena | M. Paganelli | L. Aldrighetti

Computer assisted navigation of IRE needles in ablation of a liver tumour J. Freedman, SwedenD. Stillström | J. Engstrand | H. Nilsson | M. Peterhans | E. Jonas

Outcome of patients undergoing liver surgery for HCC in the period of ERAS approach and laparoscopy. A comparative study F. Ratti, Italy

F. Cipriani | R. Ariotti | M. Catena | M. Paganelli | L. Aldrighetti

Diagnosis and management of bile leak after hepatectomy: results of a prospective analysis of 475 hepatectomiesA. Kasangian, Italy

M. Donadon | G. Costa | M. Cimino | L. Viganò | F. Procopio | D. Del Fabbro | A. Gatti | G. Torzilli

Parenchyma-sparing liver surgery for large segment 1 tumors. Ultrasound-guided lateral and superior approaches as safe alternative to major hepatectomy G. Costa, Italy

L. Viganò | F. Procopio | M. Donadon | M. Cimino | D. Del Fabbro | A. Palmisano | G. Torzilli

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CHOLANGIO DAY SATURDAY JANUARY 24th, 2015

CHOLANGIOCARCINOMA Chairman: P. Invernizzi8:30 am Epidemiology of cholangiocarcinoma D. Alvaro

TREATMENT OF CHOLANGIOCARCINOMA Chairmen: N. Bassi, A. Guglielmi8:45 am Surgery for gallbladder cancer G. Ercolani9:00 am Surgery for perihilar and hilar cholangiocarcinoma T. Ebata9:15 am Surgery for intrahepatic cholangiocarcinoma D. Ribero

9:30 am Chemotherapy for cholangiocarcinoma J. Valle9:45 am New histological features in cholangiocarcinoma L. Di Tommaso

10:00 am Discussion10:20 am Coffee Break

TREATMENT FOR NET METASTASES Chairmen: C. Carnaghi, A. Lania10:40 am Liver resection and transplantation V. Mazzaferro10:55 am TAE / TACE / TARE V. Vilgrain11:10 am Radioreceptorial imaging and treatment L. Bodei11:25 am Medical treatment K. Oberg11:40 am Discussion

12:00 pm End of the day

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SESSION 9 | oral presentations SATURDAY JANUARY 24th, 2015 9:00 am - 10:00 amChairmen: I. Endo, E. Jovine

9Indocyanine green test does not predict chemotherapy-associated liver injury N. Russolillo, Italy

S. Langella | S. Perotti | R. Lo Tesoriere | F. Forchino | A. Ferrero

Can hepatic resection provide a long-term cure to patients with Intrahepatic Cholangiocarcinoma?A. Vitale, Italy

G. Spolverato | S. Alexandrescu | H. P. Marques | L. Aldrighetti | T. Clark Gamblin | S. K Maithel | C. Pulitano | T. W. Bauer | F. Shen | G. A. Poultsides | J. W. Marsh | T. M. Pawlik

Neoadjuvant Chemotherapy for gallbladder carcinoma. Does it increase resectability? S. Singh, IndiaN. Gupta | D. Raj

Klatskin mimicking lesions, the Niguarda experience F. Ferla, ItalyA. Barcella | S. Di Sandro | A. Lauterio | I. Mangoni | R. De Carlis | A. Giacomoni | L. De Carlis

Learning Curve of Laparoscopic Left Lateral Sectionectomy: a feasible and safe stairway for a gold standard procedure. Results from an international multi-institutional analysis on 245 cases from four single surgeons F. Ratti, Italy

L. Barkhatov | F. Tomassini | F. Cipriani | B. Edwin | M. Abu Hilal | R. Troisi | L. Aldrighetti

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SESSION 10 | video presentations SATURDAY JANUARY 24th, 2015 10:30 am - 11:30 amChairmen: G. Honda, G. Belli

10Laparoscopic left lateral sectionectomy extended to segment 4b in a 74-year old woman with juvenile liver hemangioma N. Belev, Bulgaria

M. Slavchev | P. Rusev| B. Atanasov | I. Bodurov

Left hepatectomy extended to paracaval segment plus partial infrahepatic anterior vena cava wall resection and recostruction of the middle hepatic vein using left portal venus graft with extracorporeal circulation under in situ hypothermia G. Batignani, Italy

B. Pesi | T. Nelli | F. Giudici | R. Addasi | D. Zambonin | L. Moraldi | S. Scaringi

Middle hepatic vein reconstruction with a renal cyst patch for the radical resection of cholangioracinoma involving the caval confluence, using the minor-but-complex approach L. Urbani, Italy

R. Balestri | C. Leoni | G. Licitra | V. Prosperi | G. Masi | A. Fontana | P. Boraschi | M. Castagna | P. Buccianti

Laparoscopic posterosuperior hepatic pericystectomy of Giant Cystic Echinococcosis E. Francone, ItalyC. Feleppa | L. D’Ambra | S. Bruno | E. Falco | S. Berti

Laparoscopic resection of liver metastases from small bowel neuroendocrine tumor in previous open right hepatectomy C. Feleppa, Italy

M. Imperatore | S. Olcese | C. Eretta | M. Di Martino | E. Francone | S. Berti

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Multimodality approach to carcinoma gall bladder: a single center experience. S. Singh, IndiaN. Gupta | D. Ram

Outcome of pT2 gallbladder cancer according with the type of regional lymphadenectomy D.E. Park, South KoreaG.O. Jung | K.Y. Kim

Open Radiofrequency Ablation of Hepatocellular Carcinoma in the difficult location for percutaneous technique. I.Y. Park, South Korea

H.J. Choi

Autologous stem cell transplantation for the treatment of hepatocellular cancer K.H. Ryu, JapanH.S. Han

Sorafenib Case Report Keri L. Pinnock, NY, USAV. Dubrovskaya

Results of hepatic resection in patients with multifocal hepatocellular carcinoma B. Pesi, ItalyG. Batignani | T. Nelli | L. Moraldi

Surgical treatment of colorectal cancer liver metastases in Latvia oncology center L. Lauka, LatviaA. Sivins | I. Nemiro | I. Kreice | S. Gerkis | I. Jelovskis | A. Pcolkins | G. Ancans

Right extended hepatectomy with biliary and colonic resection in one stage A. Ferrarese, ItalyS. Olcese | S. Bruno | L. D'Ambra | C. Feleppa | S. Berti

Intraoperative radiotherapy in liver colorectal metastasis combine treatment A. Karpov, RussiaA.V. Shabunin | M.M. Tavobilov | D.N. Grekov

Laparoscopic vs Open resection for colorectal liver metastases:a non-randomized single-center study with propensity-score analysis M. Costa, Italy

N. de Angelis | M. Disabato | C. Salloum | P. Compagnon | F. Brunetti | A. Laurent | D. Azoulay

Methods of thermal ablation in combination with hepatic artery chemoembolization in treatment of patients with colorectal cancer liver metastases P.A. Drozdov, RussiaP

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A.V. Shabunin | V.V. Bedin | D.N. Grecov | M.M. Tavobilov

Surgical resection for non-colorectal, non-neuroendocrine liver metastases New insights, new attitudes, new opportunities A. B. Almeida, Portugal

R. Bessa de Melo | L. Graça | J. Costa Maia

Multimodality approach in the treatment of patients with hepatic colorectal cancer metastases: single center 6 years experience V. Solovov, Russia

M. Vozdvizhenskiy

Multiple bilobar colorectal liver metastases. Different insights a common goal: improve the outcome. A. Percivale, Italy

G. Griseri | M. Ceriotti | A. Franceschi | R. Pellicci

Single center experience in the management of ruptured liver tumors H. Alexandrino, PortugalL. Ferreira | R. Martins | M. Serôdio | M. Martins | J. Guilherme Tralhão | F. Castro e Sousa

Laparoscopic perspectives for distal biliary obstruction A. Ferrarese, ItalyL. D’Ambra | E. Francone | S. Berti | C. Feleppa | E. Falco

Delayed diagnosis of liver echinococcosis due to radiological misinterpretation: a case report L. Lauka, LatviaV. Krumins | G. Ancans | S. Gerkis | A. Pcolkins | I. Jelovskis | A. Sivins

Experimental study on hepatic vascular elasticity S. Di Domenico, ItalyR. Repetto | A. Stocchino | F. Barberis | M. Capurro | F. Grillo | F. De Cian

Experimental study on hepatic vascular resistance S. Di Domenico, ItalyR. Repetto | A. Stocchino | F. Barberis | M. Capurro | F. Grillo | F. De Cian

A successful right hemihepatectomy for patient with right-sided round ligament T. Matsumoto, JapanH. Yazawa | Y. Iso | K. Kubota

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G.K. Abou-Alfa, NY, USAR. Ada, FranceL. Aldrighetti, ItalyD. Alvaro, ItalyL. Balzarini, ItalyN. Bassi, ItalyJ. Belghiti, FranceG. Belli, ItalyL. Bodei, ItalyF. Calise, ItalyC. Carnaghi, ItalyD. Cherqui, FranceA. Chiti, ItalyU. Cillo, ItalyM. Colombo, ItalyL. Dawson, CanadaL. De Carlis, ItalyE. De Santibanes, Argentina

L. Di Tommaso, ItalyM. Donadon, ItalyT. Ebata, JapanD. Elias, FranceI. Endo, JapanG. Ercolani, ItalyA. Falcone, ItalyA. Ferrero, ItalyG. Folprecht, GermanyD. Fuks, FranceF. Giuliante, ItalyD. Goere, FranceA. Guglielmi, ItalyH.S. Han, South KoreaT. Helmberger, GermanyG. Honda, JapanP. Invernizzi, ItalyW. Jarnagin, NY, USA

E. Jovine, ItalyH. Kaneko, JapanH.J. Kim, South KoreaN. Kokudo, JapanM. Kudo, JapanA. Lania, ItalyR. Lencioni, Italy J. Lerut, BelgiumP. Majno, SwitzerlandM. Makuuchi, JapanO. Matsui, JapanV. Mazzaferro, ItalyK. Oberg, SwedenF. Orsi, ItalyY.N. Park, South KoreaR. Pellicci, ItalyA. Pinna, ItalyG. Poston, UK

F. Procopio, ItalyD. Ribero, ItalyL. Rimassa, ItalyM. Roncalli, ItalyE. Rosso, ItalyL. Rubbia-Brandt, SwitzerlandR. Santambrogio, ItalyM. Scorsetti, ItalyS. Shiina, JapanL. Solbiati, ItalyO. Soubrane, FranceG. Torzilli, ItalyF. Trevisani, ItalyM. Unno, JapanJ. Valle, UKJN. Vauthey, TX, USAL. Viganò, ItalyV. Vilgrain, France

FACULTY

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SPONSOR

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MEETING VENUE

HUMANITAS CONGRESS CENTRE Via Manzoni, 113 - Rozzano - Milan

EXECUTIVE COMMITTEEJacques Belghiti, Sheung Tat Fan, Norihiro Kokudo, Sung-Gyu Lee, Masatoshi Makuuchi, Jean-Nicolas Vauthey, Guido Torzilli

CONGRESS CHAIRMANGuido Torzilli

SCIENTIFIC COORDINATORSMatteo Donadon, Luca Viganò

SCIENTIFIC SECRETARIATDaniele Del Fabbro, Angela Palmisano, Fabio Procopio, Matteo Cimino, Guido CostaDepartment of Hepatobiliary and General SurgeryHumanitas Research HospitalSchool of Medicine University of Milan

LOCAL ORGANIZING COMMITTEEL. Balzarini, A. Chiti, P. Invernizzi, A. Lania, M. Montorsi, V. Pedicini, D. Poretti, M. Roncalli, A. Santoro, M. Scorsetti

ENDORSED BY

INFO & REGISTRATION:

ORGANIZING SECRETARIAT

MATERIA PRIMA T. 03631848776 - F. 03631920301www.materia1a.it - [email protected]

www.ewalt.orgEndorsed

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