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ATL / 2011 // PROFORMA INVOICE // 30 August, 2011 Viatsa Email: [email protected] Kind Attn: Mr. Anil Chawala Dear Sir, Sub: Analytical Technologies HPLC System We would like thank you very much for your email inquiry regarding your requirement for HPLC System please find our Proforma Invoice for the same. I. Analytical Technologies Isocratic HPLC System: Sr.No. Description Qty. Price in INR Analytical Technologies HPLC System with variable Wave Detector & necessary accessories, Consisting of: 1 Set 01. Analytical Technologies Isocratic Pump Specification Delivery method : double pistons, main & auxiliary Pump head :10 ml SS/Bio analytical ,upgradable to 50ml, 100ml,250ml,500ml,1000ml by exchangeable heads Maximum working pressure: 10 ml pump head 42 Mpa for SST/30 Mpa for PEEK. Flow Range : 10 ml pump head 0.001-9.999ml/min Flow rate accuracy : 0.5% measurement at 1ml/min Display : 320 X 240 blue background colour Protection : Pmax& Pmin Data automatically saved after Power down System connection: 1/16” capillaries Control : Stand-along mode by front keypad HPG Mode: one pump work as master, Others work as slave. RS232 by PC using communication protocol Power Supply : AC220V, 50Hz,400W Dimensions and weight: 410 x 180 x 270 x 10 kg. 1 02. Analytical Technologies UV-VIS Variable Wave Detector - Detector Wavelength Range: 190nm-900 nm - Wavelength Precision: < ±0.1nm - Wavelength accuracy: < ±0.3nm - Optional bandwidth: 6nm - Rise time: 0.0s-9.9s - Baseline noise: < ±0.5x10 -5 AU (empty cell, 254nm, time: 60min) - Flow cell: Analytical flow cell: optical path length 10mm: volume 10uL semi-preparative flow cell: optional path length 3mm; volume 5uL - Light source: Deuterium lamp & Tungsten - Power: AC 110V/220V, 50Hz/60Hz - Consumption: 110W - Dimensions: 420mm x 280mm x 175mm 1 03. Analytical Technologies Manual Injector with Automatic Start 1 Contd…2/- Analytical Technologies Limited (An Iso 9001Analytical Group Co.) Corporate & Reg. Office: Analytical House, E67 & 68, Ravi Park, Opp. Sainath Park, Vasna Road, Baroda,Gujarat–390015, INDIA. Tel: 0091- 265-2253620, 3208026, 3252840 Telefax: 0091-265-2254392 Email: [email protected] , [email protected] , [email protected] Web: www.ais-india.com / www.analyticalgroup.net Sales & Support Offices: across the country; Distributors & Channel partners World Wide.

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ATL / 2011 // PROFORMA INVOICE //30 August, 2011

ViatsaEmail: [email protected] Kind Attn: Mr. Anil ChawalaDear Sir, Sub: Analytical Technologies HPLC System

We would like thank you very much for your email inquiry regarding your requirement for HPLC System please findour Proforma Invoice for the same.

I. Analytical Technologies Isocratic HPLC System:

Sr.No. Description Qty. Price in INRAnalytical Technologies HPLC System with variable Wave Detector &necessary accessories, Consisting of:

1 Set

01. Analytical Technologies Isocratic Pump Specification

Delivery method : double pistons, main & auxiliary Pump head :10 ml SS/Bio analytical ,upgradable to 50ml,

100ml,250ml,500ml,1000ml by exchangeable heads Maximum working pressure: 10 ml pump head 42 Mpa for

SST/30 Mpa for PEEK. Flow Range : 10 ml pump head 0.001-9.999ml/min Flow rate accuracy : 0.5% measurement at 1ml/min Display : 320 X 240 blue background colour Protection : Pmax& Pmin Data automatically saved after

Power down System connection: 1/16” capillaries Control : Stand-along mode by front keypad HPG Mode:

one pump work as master, Others work as slave. RS232 by PC using communication protocol

Power Supply : AC220V, 50Hz,400W Dimensions and weight: 410 x 180 x 270 x 10 kg.

1

02. Analytical Technologies UV-VIS Variable Wave Detector - Detector Wavelength Range: 190nm-900 nm - Wavelength Precision: <±0.1nm- Wavelength accuracy: <±0.3nm- Optional bandwidth: 6nm- Rise time: 0.0s-9.9s- Baseline noise: <±0.5x10-5 AU (empty cell, 254nm, time: 60min)- Flow cell: Analytical flow cell: optical path length 10mm: volume 10uL

semi-preparative flow cell: optional path length 3mm; volume 5uL- Light source: Deuterium lamp & Tungsten - Power: AC 110V/220V, 50Hz/60Hz- Consumption: 110W- Dimensions: 420mm x 280mm x 175mm

1

03. Analytical Technologies Manual Injector with Automatic Start 1Contd…2/-

Analytical Technologies Limited (An Iso 9001Analytical Group Co.)Corporate & Reg. Office: Analytical House, E67 & 68, Ravi Park, Opp. Sainath Park, Vasna Road, Baroda,Gujarat–390015, INDIA.Tel: 0091- 265-2253620, 3208026, 3252840 Telefax: 0091-265-2254392 Email: [email protected], [email protected], [email protected] Web: www.ais-india.com / www.analyticalgroup.net Sales & Support Offices: across the country; Distributors & Channel partners World Wide.

// 2 //

Sr.No. Description Qty. Price in INR 04. Analchrom 21 CFR/FDA complaint Chromatography Station for 32-bit

windows Chromatography software for data acquisition and data processing

SW Package: SW on a CD, HW key (dongle), cables, manuals, A/D converter

(optional)

A/D converters: Proprietary only – internal PCI, external USB, TCP/IP

Operating systems: Microsoft Windows 2000, XP, any localization, MS Vista 32bit

(Compatibility table – refer to datasheet D016)

PC Requirements: Refer to datasheet D016 – Compatibility Table for further information.

Number of connected instruments: Up to 4 chromatography/ Instruments (= up to 4 time basis) at a time

each up to 12 signals/ channelsData acquisition:

Any detector with voltage output: up to 10m distance using USB andPCI converters or through Ethernet using the Net – PDA for dataacquisition from distant places

Digital acquisition: for selected chromatographs, e.g. Agilent, Knauer,etc. (Refer to datasheet D004 – The list of controlled instruments).

Measuring ranges: Bipolar: 156, 1250, 10000mV, Integration frequency: up to 400 Hz, 24-bit resolution

GLP / 21 CFR Part 11 requirements: Password protection / expiration, Electronic signature, Audit Trails,

User Accounts with access rights, raw data and history of modificationstored in chromatogram, Validation

Co-operation with autosamplers: The software cooperates with all autosamplers in active or passive

mode by synchronization on TTL signal level. Direct control ofselected autosamplers is available (refer to The list of controlledinstruments, code D004)

Integration: 27-integration parameter, such as Peak Width, Threshold, Tangent

Slope Ratio, etc. Integration parameters are programmable in Time,automatic reintegration.

Calculation types: Both without and with calibration (internal and external standard

methods), parameters of individual peaks for assessing both the Efficiency of the column and the chromatographic system as a whole,

1 Set

Contd…3/-

Analytical Technologies Limited (An Iso 9001Analytical Group Co.)Corporate & Reg. Office: Analytical House, E67 & 68, Ravi Park, Opp. Sainath Park, Vasna Road, Baroda,Gujarat–390015, INDIA.Tel: 0091- 265-2253620, 3208026, 3252840 Telefax: 0091-265-2254392 Email: [email protected], [email protected], [email protected] Web: www.ais-india.com / www.analyticalgroup.net Sales & Support Offices: across the country; Distributors & Channel partners World Wide.

// 3 //

Sr.No. Description Qty. Price in INRSST module for establishing deviations and reproducibility of selectedparameters

Calibrations: 6 types of calibration curves, up 20 levels, Reference Peaks, Groups,

unlimited number of standards (peaks), LOD, LOQ

Work with chromatograms: Overlay of unlimited number of chromatograms, mathematical

operations with. Chromatograms, custom labels and setting forchromatograms

Automation: Sequences, Post Run – automatic launching of selected commands

and applications immediately after the chromatogram acquisition,Batch processing, command line parameters

Presentation of results: Result and Summary Tables, both integrated and customizable,

columns with user-defined calculation, export in text or databaseformat

Calculations: Custom: 12 predefined mathematical operators, 15 basic and

summary functionsSpecial: Kovats indexes, noise / drift determination

Reports: Custom protocol Layouts, Print Preview, Print to PDF file, E-mail

reportData export:

ASCII, AIA, dBase, LIMS

Data import: ASCII, AIA, LIMS

Multi-user environment: Selectable system of user accounts with independently customizable

behavior and appearance for individual users

Network environment: Easy off – line (At the file level) data sharing among all stations in a

local network

Control modules: Refer to datasheet D004 – The list of controlled instruments

Extensions: GPC, PDA, CE, EA, Installation qualification (IQ) Test, Validation Kit,

SST module, LIMS Interface

Separate Solutions: Clarity Lite, Clarity Offline – refer to datasheet D007 for feature

Contd…4/-

Analytical Technologies Limited (An Iso 9001Analytical Group Co.)Corporate & Reg. Office: Analytical House, E67 & 68, Ravi Park, Opp. Sainath Park, Vasna Road, Baroda,Gujarat–390015, INDIA.Tel: 0091- 265-2253620, 3208026, 3252840 Telefax: 0091-265-2254392 Email: [email protected], [email protected], [email protected] Web: www.ais-india.com / www.analyticalgroup.net Sales & Support Offices: across the country; Distributors & Channel partners World Wide.

// 4 //

Sr.No. Description Qty. Price in INRComparison OEM version upon request

Support, Warranty: Automatic update from Web, free software updates, free access to on-

line knowledge database, on – line technical support, 3 yearshardware warranty

05 Column C18, 250mm x 4.6mm x 5um 106 Accessories

a) External sample loop 20ul SS: 1 b) SS Mobile Phase Filter 2um, 1/8”: 1

c) Accessories like tubing, nuts, ferrules, fittings etc. : 1 set

1 set

Total Ex-works Price 7,50,000.00 Less: Special Discount 25% 1,87,500.00

After discounted ex-works Price 5,62,500.00

TERMS & CONDITIONS:

01. Price : Ex- works Baroda02. Validity : 30 Days 03. Delivery : 4-8 weeks on receipt of your order & Advance Payment 04. Octroi : As applicable 05. Vat : 5% 06. Excise will be charged at Actual.07. Packing, forwarding & handling Charges: 3%08. Air Freight, Insurance: 4%09. Payment : 100 % advance payment by means of Bankers Draft drawn or Irrevocable L/C In favour of Analytical Technologies Limited, Baroda

Thanking you and looking forward to the pleasure of supporting your Quality Control and Research activities bysupplying our products, technologies and Services.

Yours sincerely,For ANALYTICAL TECHNOLOGIES LIMITED (An Iso 9001 Analytical Group Co.)

Smital Patel Biomed Co-ordinator Email: [email protected] www.analyticalgroup.netwww.ais-india.com

Analytical Technologies Limited (An Iso 9001Analytical Group Co.)Corporate & Reg. Office: Analytical House, E67 & 68, Ravi Park, Opp. Sainath Park, Vasna Road, Baroda,Gujarat–390015, INDIA.Tel: 0091- 265-2253620, 3208026, 3252840 Telefax: 0091-265-2254392 Email: [email protected], [email protected], [email protected] Web: www.ais-india.com / www.analyticalgroup.net Sales & Support Offices: across the country; Distributors & Channel partners World Wide.