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8/14/2019 Introduction to Econometrics- Stock & Watson -Ch 11 Slides.doc
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Experiments and Quasi-Experiments
(SW Chapter 11)
Why study experiments? Ideal randomized controlled experiments provide a benchmark for assessing observational studies.
Actual experiments are rare ($$$ but influential. !xperiments can solve the threats to internal validity
of observational studies" but they have their o#n
threats to internal validity.
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&hinking about experiments helps us to understand'uasi%experiments" or natural experiments") in #hichthere some variation is as if) randomly assigned.
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Terminology: experiments and quasi-experiments An experiment is designed and implemented
consciously by human researchers. An experimententails conscious use of a treatment and control group#ith random assignment (e.g. clinical trials of a drug
A quasi-experiment or natural experiment has a
source of randomization that is as if) randomlyassigned" but this variation #as not part of a consciousrandomized treatment and control design.
Program evaluation is the field of statistics aimed atevaluating the effect of a program or policy" forexample" an ad campaign to cut smoking.
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Di erent types o experiments: three examples
,linical drug trial- does a proposed drug lo#ercholesterol?
o Y cholesterol levelo X treatment or control group (or dose of drug
/ob training program (/ob &raining 0artnership Acto Y has a 1ob" or not (or Y #age incomeo X #ent through experimental program" or not
,lass size effect (&ennessee class size experimento Y test score (2tanford Achievement &est
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o X class size treatment group (regular" regular 4
aide" small
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!ur treatment o experiments: "rie outline
Why (precisely do ideal randomized controlledexperiments provide estimates of causal effects?
What are the main threats to the validity (internal andexternal of actual experiments 6 that is" experiments
actually conducted #ith human sub1ects? 7la#s in actual experiments can result in X and u being
correlated (threats to internal validity .
2ome of these threats can be addressed using theregression estimation methods #e have used so far-multiple regression" panel data" I8 regression.
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#deali$ed Experiments and Causal E e%ts(SW Se%tion 11&1)
An ideal randomized controlled experiment randomlyassigns sub1ects to treatment and control groups.
:ore generally" the treatment level X is randomlyassigned-
Y i ; 4 X i 4 ui
If X is randomly assigned (for example by computer
then u and X are independently distributed and E (ui< X i ;" so =>2 yields an unbiased estimator of .
&he causal effect is the population value of in an
ideal randomized controlled experiment %
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Estimation o %ausal e e%ts in an ideal randomi$ed%ontrolled experiment
@andom assignment of X implies that E (ui< X i ;. &hus the =>2 estimator $A is unbiased.
When the treatment is binary" $A is 1ust the difference
in mean outcome ( Y in the treatment vs. controlgroup ( treated Y 6 control Y .
&his differences in means is sometimes called the
differences estimator &
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'otential 'ro"lems ith Experiments in 'ra%ti%e(SW Se%tion 11& )
Threats to #nternal *alidity. Failure to randomize (or imperfect randomization
for example" openings in 1ob treatment program arefilled on first%come" first%serve basisC latecomers arecontrols
result is correlation bet#een X and u
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Threats to internal +alidity, %td&
*. Failure to follow treatment protocol (or partialcompliance
some controls get the treatment some treated) get controls
errors%in%variables) bias- corr( X "u ; Attrition (some sub1ects drop out suppose the controls #ho get 1obs move out of to#nC
then corr( X "u ;
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Threats to internal +alidity, %td&.& Experimental effects
experimenter bias (conscious or subconscious -treatment X is associated #ith extra effort) or
extra care") so corr( X "u ; sub1ect behavior might be affected by being in an
experiment" so corr( X "u ; (Ea#thorne effect
/ust as in regression analysis #ith observational data"
threats to the internal validity of regression #ithexperimental data implies that corr( X "u ; so =>2 (thedifferences estimator is biased./eorge Elton 0ayo and the a thorne Experiment
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2ub1ects in the Ea#thorne plant experiments" D*3 6 D+*
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Threats to External *alidity
. Fonrepresentative sample*. Fonrepresentative treatment) (that is" program or
policy+. General e'uilibrium effects (effect of a program can
depend on its scaleC admissions counseling 3. &reatment v. eligibility effects (#hich is it you #ant
to measure- effect on those #ho take the program" orthe effect on those are eligible
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2egression Estimators o Causal E e%ts 3singExperimental Data
(SW Se%tion 11&.) 7ocus on the case that X is binary (treatmentHcontrol . =ften you observe sub1ect characteristics" W i" " W ri. !xtensions of the differences estimator-
o can improve efficiency (reduce standard errorso can eliminate bias that arises #hen-
treatment and control groups differ
there is conditional randomization)there is partial compliance
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&hese extensions involve methods #e have alreadyseen 6 multiple regression" panel data" I8 regression
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Estimators o the Treatment E e%t 1 using
Experimental Data ( X 4 1 i treated, 5 i %ontrol)
Dep&+"le
#nd&+"le(s)
method
differences Y X =>2
differences%in%differences
Y
Y after 6 Y before
X =>2 ad1usts for initialdifferences bet#eentreatment and control
groups
differences #ithaddJl regressors
Y X "W "" W n
=>2 controls foradditional sub1ectcharacteristics W
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Estimators ith experimental data, %td&Dep&+"le
#nd&+"le(s)
method
differences%in%differences #ithaddJl regressors
Y Y after 6 Y before
X "W "" W n
=>2 ad1usts for groupdifferences 4 controlsfor sub1ect charJs W
Instrumentalvariables
Y X &2>2 Z initial randomassignmentC
eliminates bias from partial compliance
&2>2 #ith Z initial random assignment also can beapplied to the differences%in%differences estimator andthe estimators #ith additional regressors ( W Js
The di eren%es-in-di eren%es estimator%
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2uppose the treatment and control groups differsystematicallyC maybe the control group is healthier(#ealthierC better educatedC etc.
&hen X is correlated #ith u" and the differencesestimator is biased.
&he differences%in%differences estimator ad1usts for pre%experimental differences by subtracting off eachsub1ectJs pre%experimental value of Y
o beforeiY value of Y for sub1ect i before the expt
o after iY value of Y for sub1ect i after the expt
o Y i after iY 6before
iY change over course of expt
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$diffs in diffs ( "treat after Y 6 "treat beforeY 6 ( "control after Y 6 "control beforeY
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The di eren%es-in-di eren%es estimator, %td .
( Kifferences) formulation-
Y i ; 4 X i 4 ui
#hereY i after iY 6
beforeiY
X i if treated" ; other#ise
$
A is the diffs%in%diffs estimator
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The di eren%es-in-di eren%es estimator, %td .
(* !'uivalent panel data) version-
Y it ; 4 X it 4 * D it 4 +G it 4 vit " i " " n
#here
t (before experiment " * (after experiment D it ; for t " for t *G it ; for control group" for treatment group
X it if treated" ; other#ise
D it G it interaction effect of being in treatment group in the second period
$
A is the diffs%in%diffs estimator %*
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#n%luding additional su"6e%t %hara%teristi%s ( W 7s)
&ypically you observe additional sub1ect characteristics"W i" " W ri
Kifferences estimator #ith addJl regressors-
Y i ; 4 X i 4 *W i 4 4 r 4 W ri 4 ui
Kifferences%in%differences estimator #ith W Js-
Y i ; 4 X i 4 *W i 4 4 r 4 W ri 4 ui
%**
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#here Y i after iY 6before
iY .
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Why in%lude additional su"6e%t %hara%teristi%s ( W 7s)8
. Efficiency - more precise estimator of (smallerstandard errors
*. Check for randomization . If X is randomly assigned"then the =>2 estimators #ith and #ithout the W Js
should be similar 6 if they arenJt" this suggests that X #asnJt randomly designed (a problem #ith the expt.
Note - &o check directly for randomization"regress
X on the
W Js and do a
%test.
+. !d"ust for conditional randomization (#e$ll return tothis later%
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Estimation hen there is partial %omplian%e,onsider diffs%in%diffs estimator" X actual treatment
Y i ; 4 X i 4 ui 2uppose there is partial compliance- some of the
treated donJt take the drugC some of the controls go to 1ob training any#ay
&hen X is correlated #ith u" and =>2 is biased 2uppose initial assignment" Z " is random &hen ( corr( Z " X ; and (* corr( Z "u ;
&hus can be estimated by &2>2" #ith instrumentalvariable Z initial assignment
&his can be extended to W Js (included exog. variables
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Experimental Estimates o the E e%t o 2edu%tion: The Tennessee Class Si$e Experiment
(SW Se%tion 11&9)0ro1ect 2&A@ (2tudent%&eacher Achievement @atio
3%year study" $ * million Lpon entering the school system" a student #as
randomly assigned to one of three groups-o regular class (** 6 *5 studentso regular class 4 aide
o small class ( + 6 students regular class students re%randomized after first year to
regular or regular4aide Y 2tanford Achievement &est scores
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De+iations rom experimental design
0artial compliance-o ;M of students s#itched treatment groups because
of incompatibility) and behavior problems) 6 ho#much of this #as because of parental pressure?
o Fe#comers- incomplete receipt of treatment forthose #ho move into district after grade
Attrition
o students move out of districto students leave for privateHreligious schools
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2egression analysis
&he differences) regression model-Y i ; 4 &mallClass i 4 * 'eg!ide i 4 ui
#here&mallClass i if in a small class
'eg!ide i if in regular class #ith aide
Additional regressors ( W Js
o teacher experienceo free lunch eligibilityo gender" race
%*B
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Kifferences estimates (no W Js
%*D
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%+;
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o "ig are these estimated e e%ts8 0ut on same basis by dividing by std. dev. of Y Lnits are no# standard deviations of test scores
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Eo# do these estimates compare to those from the,alifornia" :ass. observational studies? (,h. 3 6
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%++
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Summary: The Tennessee Class Si$e Experiment
@emaining threats to internal validity partial complianceHincomplete treatment
o can use &2>2 #ith Z initial assignmento &urns out" &2>2 and =>2 estimates are similar
(Nrueger ( DDD " so this bias seems not to be large
:ain findings-
&he effects are small 'uantitatively (same size asgender difference
!ffect is sustained but not cumulative or increasing biggest effect at the youngest grades
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What is the Di eren%e et een a Control *aria"leand the *aria"le o #nterest8
(SW ;pp& 11&.)
!xample- free lunch eligible) in the 2&A@ regressions ,oefficient is large" negative" statistically significant
0olicy interpretation- (aking students ineligible for a free school lunch #ill im)rove their test scores*
Is this really an estimate of a causal effect?
Is the =>2 estimator of its coefficient unbiased? ,an it be that the coefficient on free lunch eligible)
is biased but the coefficient on &mallClass is not?
%+5
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%+9
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E+am)le - free lunch eligible") ctd. ,oefficient on free lunch eligible) is large" negative"
statistically significant 0olicy interpretation- (aking students ineligible for a free school lunch #ill im)rove their test scores*
Why (precisely can #e interpret the coefficient on
&mallClass as an unbiased estimate of a causal effect" but not the coefficient on free lunch eligible)?
&his is not an isolated exampleO
o =ther control variables) #e have used- gender"race" district income" state fixed effects" time fixedeffects" city (or state population"
What is a control variable) any#ay?%+
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Simplest %ase: one X , one %ontrol +aria"le W
Y i ; 4 X i 4 *W i 4 ui
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7urther suppose W is correlated #ith u
%+D
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Y i ; 4 X i 4 *W i 4 ui&u))ose- &he control variable W is correlated #ith u Given W ; (ineligible " X is randomly assigned Given W (eligible " X is randomly assigned.
,hen- Given the value of W " X is randomly assignedC &hat is" controlling for W " X is randomly assignedC
&hus" controlling for W " X is uncorrelated #ith u :oreover" E (u< X "W doesnJt depend on X &hat is" #e have conditional mean independence:
%3;
E( X"W E( W
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E (u< X "W E (u
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#mpli%ations o %onditional mean independen%e
Y i ; 4 X i 4 *W i 4 ui
2uppose E (u
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#mpli%ations o %onditional mean independen%e: &he conditional mean of Y given X and W is
E (Y i< X i"W i ( ; 4 ; 4 X i 4 ( 4 * W i &he effect of a change in X under conditional mean
independence is the desired causal effect-
E (Y i< X i +4 +"W i 6 E (Y i< X i +"W i +or
( < " ( < "i i i i i i E Y X + + W E Y X + W
+
= + =
If X is binary (treatmentHcontrol " this becomes-
( < " ( < ;"i i i i i i E Y X W E Y X W
+
= =
#hich is the desired treatment effect.%3+
# li% i % di i l i d d % % d&
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#mpli%ations o %onditional mean independen%e, %td&
Y i ; 4 X i 4 *W i 4 ui
,onditional mean independence says- E (u< X "W E (u
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So, hat is a %ontrol +aria"le8
A control variable W is a variable that results in X satisfying the conditional mean independence condition-
E (u< X "W E (u
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Example : E e%t o tea%her experien%e on test s%ores:ore on the design of 0ro1ect 2&A@-
&eachers didnJt change school because of the expt. Within their normal school" teachers #ere randomly
assigned to smallHregularHreg4aide classrooms. What is the effect of X years of teacher education?
,he design im)lies conditional mean inde)endence - W school binary indicator
Given W (school " X is randomly assigned &hat is" E (u< X "W E (u
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W is plausibly correlated #ith u (nonzero school fixedeffects- some schools are betterHricherHetc than others
%3
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%3B
Example : tea%her experien%e %td&
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Example : tea%her experien%e, %td& Without school fixed effects (* " the estimated effect of
an additional year of experience is .3 ( &E . 0Controlling for the school ) (+ " the estimated effect of
an additional year of experience is . 3 ( &E . Kirection of bias makes sense-
o less experienced teachers at #orse schoolso years of experience picks up this school effect
=>2 estimator of coefficient on years of experience is
biased up #ithout school effectsC #ith school effects"=>2 yields unbiased estimator of causal effect
2chool effect coefficients donJt have a causalinterpretation (effect of student changing schools
%3D
Quasi Experiments
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Quasi-Experiments(SW Se%tion 11&=)
A quasi-experiment or natural experiment has a sourceof randomization that is as if) randomly assigned" butthis variation #as not part of a conscious randomized
treatment and control design.
o cases-(a &reatment ( X is as if) randomly assigned (=>2(b A variable ( Z that influences treatment ( X is
as if) randomly assigned (I8
%5;
T o types o quasi experiments
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T o types o quasi-experiments
(a &reatment ( X is as if) randomly assigned (perhaps
conditional on some control variables W E+- !ffect of marginal tax rates on labor supply
o X marginal tax rate (rate changes in one state"
not anotherC state is as if) randomly assigned
(b A variable ( Z that influences treatment ( X isas if) randomly assigned (I8 !ffect on survival of cardiac catheterization
X cardiac catheterizationC Z differential distance to ,, hospital
%5
E%onometri% methods
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E%onometri% methods(a &reatment ( X is as if) randomly assigned (=>2
Kiffs%in%diffs estimator using panel data methods-
Y it ; 4 X it 4 * D it 4 +G it 4 uit " i " " n#here
t (before experiment " * (after experiment D it ; for t " for t *G it ; for control group" for treatment group
X it if treated" ; other#ise
D it G it interaction effect of being in treatmentgroup in the second period
$
A is the diffs%in%diffs estimator%5*
The panel data di s in di s estimator simpli ies to
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The panel data di s-in-di s estimator simpli ies tothe >%hanges di s-in-di s estimator hen T 4
Y it ; 4 X it 4 * D it 4 +G it 4 uit " i " " n (P
7or t - D i ; and X i ; (nobody treated " so
Y i ; 4 +G i 4 ui
7or t *- D i* and X i* if treated" ; if not" soY i* ; 4 X i* 4 * 4 +G i* 4 ui*
so
Y i Y i* 6 Y i ( ; 4 X i*4 *4 +G i*4ui* 6 ( ; 4 +G i 4ui X i 4 * 4 ( ui 6 ui* (since G i G i*
or
%5+
Y 4 X 4 v " #here v u 6 u (PP
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Y i * 4 X i 4 vi #here vi ui 6 ui* (PP
%53
Di eren%es-in-di eren%es ith %ontrol +aria"les
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Di eren%es-in-di eren%es ith %ontrol +aria les
Y it ; 4 X it 4 * D it 4 +G it 4 3W it 4 4 +4r W rit 4 uit "
X it if the treatment is received" ; other#ise
G it D it ( for treatment group in second period
If the treatment ( X is as if) randomly assigned"given W " then u is conditionally mean indep. of X -
E (u< X " D"G"W E (u< D"G"W
=>2 is a consistent estimator of " the causal effectof a change in X In general" the =>2 estimators of the other
coefficients do not have a causal interpretation.%55
(b A variable ( Z that influences treatment ( X is
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(b A variable ( Z that influences treatment ( X isas if) randomly assigned (I8
Y it ; 4 X it 4 * D it 4 +G it 4 3W it 4 4 +4r W rit 4 uit "
X it if the treatment is received" ; other#ise
G it D it ( for treatment group in second period Z it variable that influences treatment but is
uncorrelated #ith uit (given W Js&2>2-
X endogenous regressor D"G"W " " W r included exogenous variables Z instrumental variable
%59
'otential Threats to Quasi-Experiments
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otential Threats to Quasi Experiments(SW Se%tion 11&?)
&he threats to the internal +alidity of a 'uasi%
experiment are the same as for a true experiment" #ithone addition.3. Failure to randomize (imperfect randomization
Is the as if) randomization really random" so that X (or Z is uncorrelated #ith u?
=&Failure to follow treatment protocol attrition9. Experimental effects (not applicable
. !nstrument invalidit" (relevance 4 exogeneity(:aybe healthier patients do live closer to ,, hospitals
6they might have better access to care in general
%5
&he threats to the external +alidity of a 'uasi%
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&he threats to the external +alidity of a uasi%experiment are the same as for an observational study.5. Fonrepresentative sample
9. Fonrepresentative treatment) (that is" program or policy
E+am)le - ,ardiac catheterization &he ,, study has better external validity thancontrolled clinical trials because the ,, study usesobservational data based on real%#orldimplementation of cardiac catheterization.
Eo#ever that study used data from the early D;Js 6 do itsfindings apply to ,, usage today?
%5B
Experimental and Quasi-Experiments Estimates in
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Experimental and Quasi Experiments Estimates ineterogeneous 'opulations
(SW Se%tion 11&@)
We have discussed the) treatment effect Qut the treatment effect could vary across individuals-
o !ffect of 1ob training program probably depends oneducation" years of education" etc.
o !ffect of a cholesterol%lo#ering drug could depend
other health factors (smoking" age" diabetes" If this variation depends on observed variables" thenthis is a 1ob for interaction variablesO
Qut #hat if the source of variation is unobserved?%5D
eterogeneity o %ausal e e%ts
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eterogeneity o %ausal e e%tsWhen the causal effect (treatment effect varies amongindividuals" the population is said to be #eterogeneous .
When there are heterogeneous causal effects that are notlinked to an observed variable-
What do #e #ant to estimate?o =ften" the average causal effect in the populationo Qut there are other choices" for example the average
causal effect for those #ho participate (effect oftreatment on the treated
What do #e actually estimate?o using =>2? using &2>2?
%9;
'opulation regression model ith heterogeneous
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opulation regression model ith heterogeneous%ausal e e%ts-
Y i ; 4 i X i 4 ui" i " " n
i is the causal effect (treatment effect for the ith individual in the sample
7or example" in the /&0A experiment" i could be zeroif person i already has good 1ob search skills
What do #e #ant to estimate?o
effect of the program on a randomly selected person(the average causal effect ) 6 our main focus
o effect on those most (least? benefitedo effect on those #ho choose to go into the program?
%9
The ;+erage Causal E e%t
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The ; erage Causal E e%t
Y i ; 4 i X i 4 ui" i " " n
&he average causal effect (or average treatment effect is the mean value of i in the population.
We can think of as a random variable- it has adistribution in the population" and dra#ing a different
person yields a different value of (1ust like X and Y
7or example" for person R+3 the treatment effect is notrandom 6 it is her true treatment effect 6 but before she
%9*
is selected at random from the population" her value of
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p p
can be thought of as randomly distributed.
The a+erage %ausal e e%t, %td&
Y i ; 4 i X i 4 ui" i " " n
&he average causal effect is E ( . What does =>2 estimate-
(a When the conditional mean of u given X is zero?
(b Lnder the stronger assumption that X is randomlyassigned (as in a randomized experiment ?
1n this case2 34& is a consistent estimator ofthe average causal effect .
%9+
!AS ith eterogeneous Causal E e%ts
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g
Y i ; 4 i X i 4 ui" i " " n (a 2uppose E (ui< X i ; so cov( ui" X i ;.
If X is binary (treatedHuntreated " $A treated Y 6 control Y
estimates the causal effect among those #ho receivethe treatment.
Why? 7or those treated" treated Y reflects the effect ofthe treatment on them . Qut #e donJt kno# ho# theuntreated #ould have responded had they beentreatedO
%93
T#e mat# - suppose X is binary and E (ui< X i ;.
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pp y ( ;&hen
$A treated Y 6 control Y
7or the treated-
E (Y i< X i ; 4 E ( i X i< X i 4 E (ui< X i
; 4 E ( i< X i
7or the controls- E (Y i< X i ; ; 4 E ( i X i< X i ; 4 E (ui< X i ;
;
&hus-$
A )
E (Y i< X i 6 E (Y i< X i ; E ( i< X i
average effect of the treatment on the treated
%95
!AS ith heterogeneous treatment e e%ts: general X
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g gith E (u i B X i ) 4 5
$
A *
XY
X
s
s
)
* XY
X
; $cov( "
var(
i i i i
i
X u X
X
+ +
; $cov( " cov( " cov( "
var(i i i i i i
i
X X X u X
X
+ +
$cov( "
var(i i i
i
X X
X
(because cov( ui" X i ;
If X is binary" this simplifies to the effect oftreatment on the treated)
Without heterogeneity" i and $A )
In general" the treatment effects of individuals #ithlarge values of X are given the most #eight
%99
(b Fo# make a stronger assumption- that X is randomly
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( g p yassigned (experiment or 'uasi%experiment . &hen#hat does =>2 actually estimate?
I X i is randomly assigned" it is distributedindependently of i" so there is no difference
bet#een the population of controls and the
population in the treatment group &hus the effect of treatment on the treated the
average treatment effect in the population.
%9
&he math-
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$A
)
$cov( "
var(i i i
i
X X
X
$ $
cov( "2 estimates the average treatment effect.
If X i is not randomly assigned but E (ui< X i ;" =>2estimates the effect of treatment on the treated.
%9B
Without heterogeneity2 the effect of treatment on the
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g y
treated and the average treatment effect are the same#* 2egression ith eterogeneous Causal E e%ts
2uppose the treatment effect is heterogeneous and theeffect of the instrument on X is heterogeneous-
Y i ; 4 i X i 4 ui (e'uation of interest
X i ; 4 i Z i 4 vi (first stage of &2>2
In general" &2>2 estimates the causal effect for those#hose value of X (probability of treatment is mostinfluenced by the instrument.
%9D
#* ith heterogeneous %ausal e e%ts, %td&
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Y i ; 4 i X i 4 ui (e'uation of interest
X i ; 4 i Z i 4 vi (first stage of &2>2
Intuition-
2uppose iJs #ere kno#n. If for some people i ;" then their predicted value of X i #ouldnJt dependon Z " so the I8 estimator #ould ignore them.
&he I8 estimator puts most of the #eight onindividuals for #hom Z has a large influence on X .
&2>2 measures the treatment effect for those #hose probability of treatment is most influenced by X .
% ;
,he math
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Y i ; 4 i X i 4 ui (e'uation of interest
X i ; 4 i Z i 4 vi (first stage of &2>2
&o simplify things" suppose- i and i are distributed independently of ( ui"vi" Z i
E (ui< Z i ; and E (vi< Z i ; E ( i ;
&hen $,&4&
)
$ $
$
(
(
i i
i
E
E
(derived in 2W App. .3
&2>2 estimates the causal effect for those individualsfor #hom Z is most influential (those #ith large i .
%
When there are heterogeneous %ausal e e%ts, hat
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TSAS estimates depends on the %hoi%e o instruments With different instruments" &2>2 estimates different
#eighted averagesOOO 2uppose you have t#o instruments" Z and Z *.
o In general these instruments #ill be influential for
different members of the population.o Lsing Z " &2>2 #ill estimate the treatment effect for
those people #hose probability of treatment ( X ismost influenced by Z
o &he treatment effect for those most influenced by Z
might differ from the treatment effect for those mostinfluenced by Z *
% *
When does TSAS estimate the a+erage %ausal e e%t8
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Y i ; 4 i X i 4 ui (e'uation of interest
X i ; 4 i Z i 4 vi (first stage of &2>2
$,&4&
)
$ $
$
((
i i
i
E E
&2>2 estimates the average causal effect (that is"$,&4&
) E ( i if-
o If i and i are independent
o If i (no heterogeneity in e'uation of interesto If i (no heterogeneity in first stage e'uation
Qut in general $,&4& does not estimate E ( i O
% +
Example - ,ardiac catheterization
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Y i survival time (days for A:I patients X i received cardiac catheterization (or not
Z i differential distance to ,, hospital
!'uation of interest-
&urvivalDays i ; 4 iCardCath i 4 ui7irst stage ( linear )robability model -
CardCath i ; 4 i Distance i 4 vi
7or #hom does distance have the great effect on the probability of treatment?
7or those patients" #hat is their causal effect i?% 3
!'uation of interest-
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&urvivalDays i ; 4 iCardCath i 4 ui7irst stage ( linear )robability model -
CardCath i ; 4 i Distance i 4 vi
&2>2 estimates the causal effect for those #hose
value of X i is most heavily influenced by Z i &2>2 estimates the causal effect for those for #hom
distance most influences the probability of treatment
What is their causal effect? ( We might as #ell go tothe ,, hospital" its not too much farther)
&his is one explanation of #hy the &2>2 estimate issmaller than the clinical trial =>2 estimate.
% 5
eterogeneous Causal E e%ts: Summary
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Eeterogeneous causal effects means that the causal (ortreatment effect varies across individuals.
When these differences depend on observable variables"heterogeneous causal effects can be estimated using
interactions (nothing ne# here . When these differences are unobserved ( i the average
causal (or treatment effect is the average value in the
population" E ( i . When causal effects are heterogeneous" =>2 and &2>2
estimate .
% 9
!AS ith eterogeneous Causal E e%ts
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X is: 2elation "et een X i andu i :
Then !AS estimates:
binary E (ui< X i ; effect of treatment on thetreated- E ( i< X i
X randomly assigned (so X i and ui are independent
average causal effect E ( i
general E (ui< X i ; #eighted average of i" placing most #eight on
those #ith large < X i 6 X 2 also estimates a causal effect- the average
effect of treatment on those most influenced by theinstrument
o In general" this is neither the average causal effect
nor the effect of treatment on the treated% B
Summary: Experiments and Quasi-Experiments
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(SW Se%tion 11& )
Experiments: Average causal effects are defined as expected values
of ideal randomized controlled experiments
Actual experiments have threats to internal validity &hese threats to internal validity can be addressed (in part by-
o panel methods (differences%in%differenceso multiple regressiono I8 (using initial assignment as an instrument
% D
Summary, %td&
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Quasi-experiments:
Suasi%experiments have an as%if) randomly assignedsource of variation.
&his as%if random variation can generate-
o X i #hich satisfies E (ui< X i ; (so estimation proceeds using =>2 C or
o instrumental variable(s #hich satisfy E (ui< Z i ;
(so estimation proceeds using &2>2 Suasi%experiments also have threats to internal vaidity
%B;
Summary, %td&
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T o additional su"tle issues:
What is a control variable?o A variable W for #hich X and u are uncorrelated"
given the value of W (conditional mean
independence- E (ui< X i"W i E (ui
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What do =>2 and &2>2 estimate #hen there is
unobserved heterogeneity of causal effects? In general" #eighted averages of causal effects-
o If X is randomly assigned" then =>2 estimates the
average causal effect.o If X i is not randomly assigned but E (ui< X i ;" =>2
estimates the average effect of treatment on thetreated.
o If E (ui< Z i ;" &2>2 estimates the average effect of
treatment on those most influenced by Z i.