Innovation Waits

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    PromotingInnovationThe Role of R&D Investment

    NGAs Innovation America Initiative Kick-Off

    Phoenix, December 5, 2006

    Mary Jo Waits, Center Director Pew Center on the States

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    The Idea-Driven Economy

    The first 100 years of our countryshistory were about who could build the

    biggest, most efficient farm.

    The second 100 years were about the raceto build efficient factories.

    The third 100 years are about ideas .-- Seth Godin

    Fast Company, August 2000

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    New Growth Theory:Stanford Economist Paul Romers Perspective

    Ingredients

    Intellectual capital

    Human capital

    Financial capital

    Recipes

    New ideas

    Entrepreneurs

    Networks

    Results

    Productivity

    Prosperity

    Cluster vitality

    Source: Collaborative Economics

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    In 1971, a small coffee shopstarts in Seattles funky PikePlace Market with a newrecipe

    Recipes combine resources innew and different ways

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    Recipes combine resources innew and different ways

    Nanotech : You start with building blocks likenanowires, nanotubes, and nanoparticles. Puttogether one way, these building blocks make acomputer. Put together in a different way, they makea biological sensor.

    Biology is another example. You have a limitednumber of building blocks, like proteins and DNA.

    Depending on how you put them together, you endup with a tissue, a worm, or a human being.

    Charles Lieber, Harvard Chemistry Professor & co-founder, Nanosys

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    Implications for Companies

    New Business ModelCompanies and entrepreneurs moving fromclosed innovation (in-house researchcapability) to open innovation model.

    Many companies are starting to innovatewith research discoveries of others.

    Harvard Professor Henry Chesborough, Open Innovation, 2003

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    Small-sized research facilities adjacentto top university research centers

    Intel expects to benefit from proximity:gain early access to promising new

    technologies

    Intels lablets

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    Applies to all companies,not just high-tech

    Procter & Gamble names director of externalinnovationGoal: 50% of its innovation fromoutside the company in 5 years

    Why? Inside more than 8,600 scientistsadvancing the industrial knowledge thatenables new offerings; outside are 1.5 million.

    So why try to invent everything internally?

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    Implications for WorkRe-Valuing the Right Brain.

    LogicalMathematical

    Linear SequentialVerbalRationalSerious

    Intuitive

    Artistic

    NonlinearSimultaneous

    Visual

    Emotional

    Playful

    See Daniel Pink, The Whole Mind: Moving from the Information Age to the ConceptualAge

    Can StayWill Go

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    Implications for StatesShifting Sources of Wealth

    Created Assets

    Top universitiesResearch centersTalented peopleEntrepreneurial cultureNetworksVibrant downtowns

    Inherited Assets

    GeographyClimateNatural ResourcesPopulation

    From: To:

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    Three Things to Remember

    1. The 21 st century will be driven by innovation.

    2. Many of the factors that give regions and states an innovativeedge are creatednot inherited.

    3. The new century will be a highly competitive oneespecially asplaces realize that key features are buildable and thus can behad by nearly any place that puts its mind to it.

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    Big Money is being Investedin R&D Assets

    California: $3 B for Stem Cell research

    Florida: $ 800 M for East Coast facility for Scripps ResearchInstitute and Burnham Institute for Medical Research ; statecovers operating costs for 7 years ($310 M)

    Georgia: $400 M for Georgia Research Alliance allocated toendowed chairs

    Kansas: American Century Funds founder is spending $1 B to build mega-biomedical research complex

    Indiana: Lilly Endowment offers $100 M to recruitintellectual capital to state colleges and universities

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    Question is, will research turninto enterprises ?

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    Important to have StrategicContinuum of Programs

    Arizona BioscienceResearchEnhancementFund

    Gaps: Tactics:Drivers: Drivers:ResearchTechnology

    DevelopmentBioFirm

    Formation

    FirmExpansion/Attraction

    Consortia/Centersaround TechPlatforms

    Federal Funds

    MatchingChallengeProgram

    TechnologyCommercializationProof of ConceptFund

    Bioscience SBIRSupport

    BioscienceEntrepreneurAssistance Cntr.

    Technology Zones

    Incubators

    University Equity

    BioSeed Fund

    Accelerators

    Research Parks

    Incentives/ TaxStudy Reviews

    Marketing & Brand

    K-12 & WorkforceDevelopment

    P r o p o s e

    d A c t

    i o n s

    Source: Battalle, 2002

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    Expertise Diversity

    Interaction

    Creativity

    EXPERTISE means talentedpeopleINTERACTION when peoplecome together, theres abetter chance for thepassionate exchange of ideas & synergies that createnew business models,marketing plans or productsDIVERSITY is important in

    generating the Next BigThing; people learn most byinteracting with people lesslike themselves.

    Just as important tounderstand Must-Haves for Innovation

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    Building Expertise

    State-sponsored Research Funds : CA, GA,TX, NJ,NY, MI, AZ, OH, OKStrategic, Focused Excellence : Georgia ResearchAlliance, CA Institutes for Science and InnovationTalent: Lilly Endowments $100 M for intellectualcapital, Georgia's 100 eminent scholars, ScienceFoundation Ireland recruiting 50 world-class scholarsby 2008New Fields and Young Talent: ASUs new mastersin genomics and biotech law; new era medicalschools; research funds marked for younginvestigators

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    Orchestrating Interaction

    Networks: UCSD CONNECT Meet the Researcher,BIOCOM ASUs supercomputer and Engineering schoolmoves to main street TempeInnovation Districts: Atlantas Technology Square,San Diego Torrey Pines, Research Triangle Park, PAsKeystone Innovation ZonePartnerships: Georgia Cancer Coalition, JointMedical School University of AZ and ASU, CITRIScombines 4 CA universitiesBerkley, Davis, Merced,Santa Cruz-- St. Louis Coalition for Plant and LifeSciences, more and more international partnerships

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    The Proximity Edge

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    Today: 3rd Biotech hub behind San Francisco & Boston

    North Torrey Pines Road: Densely packed 2-mile stretch w/ ScrippsResearch Institute, Salk Institute for Biomedical Studies, UCSD

    We can throw a rock and hit UCSD. I can hit a golf ball and hit Scripps.Everything is within walking distance. That means more heads gettogether and we do a lot of collaboration. VP at Salk Institute

    San Diego: Rise of a BioTechCluster

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    Putting people from Diverseknowledge fields and cultures

    together Silo, Solo is PassAZ Biodesign Instituteco-locates researchers from 3fields; designed for interaction

    UC Discovery Grants stress industry-universitycollaborationIncentives to encourage interdisciplinary researchRight brain and left brainMFA is the new MBAWanted: Charismatic, Collaborative scientists andresearchers

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    Arizonas Strategic Moves

    Five Big Bets on an

    innovation future

    Top Down andBottom Up

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    Five Big Bets

    Big Bet No. 1Target export-oriented, knowledge intensiveclusters to build strengths in:

    Electronics/Information TechnologyAerospaceSoftwareAdvanced Business ServicesOpticsBiosciences

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    Five Big Bets

    Big Bet No. 2Prop 301, a sales tax increase which citizensapproved in 2000, earmarks $1 billion over 20years, distributed among the states 3universities

    Arizonans recognized that K-12, community colleges, top-tier universities are a critical infrastructure for the 21 st century

    In 2003, AZ legislature approved $440 million in researchfacilities at 3 universities12 new research facilities

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    Five Big Bets

    Big Bet No. 3Genomics $90M raised in 2002 to jumpstartthe bioscience industry with attraction of TGenand IGC

    Battelle Biosciences Roadmap to develop 3areas:

    Cancer therapeuticsNeurological sciencesBioengineering

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    Five Big Bets

    Big Bet No. 4Personalized MedicineThe Virginia G. Piper Foundation creates a $50 million fund for purposes of attracting to AZs publicuniversities, research institutes, and medicalcenters 10 world class scientists, engineers,

    researchers and physicians to make AZ apioneer in personalized medicine

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    Five Big Bets

    Big Bet No. 5

    Science Foundation Arizonastateallocates $35 million to make investments innew medical, scientific and engineeringresearch and to attract top-notch research

    talent. Business leadership agree to raise$15 million over 5 years to support SFAzsoperation.

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    Lots of Alignment

    Biodesign Institute at ASUBIO5 at University of ArizonaTechnopolis entrepreneurial supportArizona Board of Regents - metrics for 301 funds

    Arizona Biomedical Collaborative3 universitiesLegislature passes Angel Investor tax creditMaricopa Community College district-- $100 M of bondissue slated for bioscience workforce prepFoundations continue to support TGen and top talentGreater Phoenix LeadershipBioscience Task ForceScience Foundation ArizonaASU first to introduce a masters program in genomicsand biotech law

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    Cities connecting to AZs BigBets

    Phoenix commits land and $50 M to secure TGen in downtownPhoenix uses $250 M of voter-approved bond money to bring ASUdowntownScottsdale invests $125 M in Los Arcos for new ASU-ScottsdaleCenter for New Technology and Innovation and provides support for Mayo Clinic R&DTucsons UA Research Park and new Critical Path InstituteFlagstaffs NAU partners with TGenSurprise opens biotechnology incubator

    More Big BetsUA/ASU Medical SchoolTribes plan biomedical campus

    Maricopa Partnership for Arts and CultureDiscovery Triangle- Phoenix, Scottsdale & Tempe

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    Key Success Factors

    Requiring funding mechanisms that createcollaborative research with tangible incentivesImproving the interface between academia andindustryFacilitating contact between researchers andentrepreneursFocusing on areas of strength and relevanceNecessitating excellence as a driver of research

    Using metrics that drive innovation andcompetitiveness

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    Strategic, Sustained Effort

    There was no single defining action,no grand program no solitary lucky

    break, no wrenching revolution.Good to great comes about by acumulative process--step by step,action by action, decision by decision,turn by turn of the flywheelthat addsup to sustained and spectacular

    results.

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