Patient RecruitmentCapabilities

Patient Identification System

Cloud Based Retention Application

Social Media Targeting

Branding and Ad Creation

Real-Time Appointment Scheduling

SMS Follow-Up Email Marketing

Site Reputation Enhancement

Website Development

Mobile-Friendly Patient Sign-Up Application

SEO Services

Physician Relations Team

In-House Call Center

WCCT GLOBAL’S PATIENT RECRUITMENT DIVISION, IN-SITE, UTILIZES THE MOST UP-TO-DATE TECHNOLOGIES AVAILABLE TO THE INDUSTRY TO EXPEDITE ENROLLMENT TIMELINES. IN-SITE OFFERS A FULLY-CUSTOMIZABLE SERVICE THAT CAN BE IMPLEMENTED WITH ANY RESEARCH PROGRAM. IN-SITE’S SERVICES CAN BE USED FOR ANY PATIENT POPULATION NEARLY ANYWHERE ON THE GLOBE.

PATIENT RECRUITMENT DIVISION IN-SITE

PATIENT RECRUITMENT DIVISION IN-SITE

In-Site Services

PATIENT RETENTION APPLICATION

Keep patients informed with real-time updates and study-related reminders using enhanced geo-targetingEnsure protocol adherence, appointment scheduling, and active participation

Distribute Study-related information or tasks via mobile platform

Give patients the option to report Adverse Events round-the-clock

Allow patients to sign documents electronically, reducing potential drop-off because of travel time and site visits

WCCT GLOBAL HAS DEVELOPED A PATIENT RETENTION PLATFORM TO ACCOMPANY IN-SITE WHICH HAS INCREASED RETENTION & ENGAGEMENT BY UP TO 40% IN SOME RESEARCH PROGRAMS. BY IMPLEMENTING THIS CUTTING-EDGE PLATFORM, SITES WILL BE ABLE TO:

• Data is provided by:• Claims clearinghouses• Electronic Medical Record

Providers• Independent Physician

Associations• Pharmacy Benefit Management

Providers

• Our system can help to:• Identify the best locations for

study sites• Show the geographic areas with

the most patients in your desired indication

• Provide data on how far patients are willing to travel for treatment

SEARCH FOR AND LOCATE YOUR DESIRED PATIENT POPULATIONS WITH WCCT GLOBAL’S PROPRIETARY PATIENT IDENTIFICATION SYSTEM. THIS SYSTEM LOCATES PATIENTS BASED ON ICD-9 CODES AND MEDICAL DATA.

PATIENT IDENTIFICATION

• Specialized Social Media Recruitment Targeting by:• Age• Gender• Interest• Location• Lifestyle• Disease State

• Creates a completely “opt-in” database of potential volunteers for your study.

SOCIAL MEDIA IS A POWERFUL TOOL FOR IDENTIFYING PATIENTS IN NEARLY ANY INDICATION, IN NEARLY ANY LOCATION IN THE WORLD. WCCT GLOBAL MAKES USE OF THIS TOOL TO QUICKLY FIND QUALIFIED PATIENTS AND ENROLL YOUR STUDY.

SOCIAL MEDIA TARGETING

• WCCT studies the conversations that your desired patient population is having in the digital sphere and translates these conversations into advertisements that will appeal to these patients and friends, family, and caregivers.

SOPHISTICATED DESIGN TEAM THAT USES DATA FROM PATIENT NETWORKS TO DEVELOP PROPER MESSAGING FOR PATIENT ENGAGEMENT.

BRANDING & AD CREATION

POTENTIAL PATIENT INPUTS DATA

IMMEDIATE EMAIL/SMS FOLLOW-UP

24/7 CALL CENTER SCHEDULING

REAL-TIME APPOINTMENT SCHEDULING

IN-SITE’S 24/7 IN-HOUSE CALL CENTER IS CAPABLE OF SCHEDULING APPOINTMENTS IN REAL-TIME AT MULTIPLE STUDY SITES, USING ANY SCHEDULING SERVICE OR PROCEDURE.

SMS FOLLOW-UP & EMAIL MARKETING

New Paid Studies for You and Your Loved Ones!Sent to 7,449 subscribers in “Study 1” at 08/28/15 09:34 AM PST

1.2kopened

Brand New Paid Volunteer Studies to Check Out!Sent to 5,058 subscribers in “Study 2” at 08/26/15 10:33 AM PST Includes 2 additional lists

1.4kopened

Brand New Paid Volunteer Studies to Check Out!Sent to 7,843 subscribers in “Study 3” at 08/25/15 09:52 AM PST Includes 1 additional lists

2kopened

IMMEDIATE EMAIL /SMS FOLLOW-UP

PHYSICIAN RELATIONS

IN-SITE HAS ACCESS TO A LARGE DATABASE OF INVESTIGATORS AND SITES THAT CAN HELP SPONSORS MAKE DECISIONS REGARDING THEIR PROGRAM IN THE FOLLOWING THERAPEUTIC AREAS:

• Allergy & Asthma• Immunology• Cardiology• Cardiovascular-

electrophysiology• Internal Medicine• Dermatology• Gastroenterology• Nephrology & HTN• Obstetrics/Gynecology• Pulmonology• Rheumatology• Plastic Surgery• Geriatrics

INVESTIGATORS

SITES

24/7 IN-HOUSE CALL CENTER

WCCT GLOBAL OFFERS A ROUND-THE-CLOCK CALL CENTER SERVICE FOR CLINICAL TRIAL PATIENT RECRUITMENT AND SCREENING. WE’VE RECRUITED AND SCREENED PATIENTS FOR OVER 4,000 RESEARCH PROGRAMS THROUGH OUR CLINICAL TRIAL CALL CENTER ALONE!

• HIPAA compliant• USA based with 24/7

international reach• Multilingual (English,

Spanish, Japanese, Korean, Chinese, & Vietnamese) to screen/recruit for Ethnobridging studies

• Capable of conducting patient pre-screening and patient scheduling

• Service customizable for any protocol

• 100% accurate data collectionfrom calls

• Recruitment and retention for Phase I-IV studies

WCCT CLINICAL TRIAL CALL CENTER DETAILS:

WEBSITE DEVELOPMENT & SEO SERVICES

RESPONSIVELY-DESIGNED WEBSITES FOR LONG-TERM, LATE PHASE CLINICAL TRIALS.

• Central location for all study-related information

• Presents an easily-accessible method for potential patients to reach out for more information

• Online location for study-sign up• Adds more authority to your

study and makes study more personable and approachable by online visitors

• Integrated process to drive organic traffic to study-specific websites for increased exposure

• Easy linking to social media channels being used to advertise your study and encourage engagement with patients

Benefits of creating a study-specific website:

SITE REPUTATION ENHANCEMENT

IMPROVES SITE REPUTATION IN PATIENTS’ VIEWPOINT THROUGH REVIEW SITES LIKE YELP, GOOGLE PLACES, AND FACEBOOK.

MOBILE-FRIENDLY PATIENT APPLICATION

AFTER CLICKING THROUGH AN ADVERTISEMENT, POTENTIAL PATIENTS WILL BE REDIRECTED TO A MOBILE-FRIENDLY, PATIENT APPLICATION PAGE WHERE THEY CAN “OPT-IN” TO RECEIVE MORE INFORMATION ABOUT YOUR PROGRAM. CONTACT INFORMATION IS STORED IN A SECURE DATABASE.

Targeted Advertisement

Patient Application Page

RecruitmentCampaign Workflow

WORKFLOW OVERVIEW

IN-SITE WILL CREATE A UNIQUE RECRUITMENT CAMPAIGN THAT IS TAILORED TO YOUR RESEARCH PROGRAM AND DESIRED PATIENT POPULATION. WHILE YOUR SPECIFIC RECRUITMENT CAMPAIGN MAY INCLUDE OTHER IN-SITE SERVICES, OUR STANDARD RECRUITMENT CAMPAIGN INCLUDES THE FOLLOWING ELEMENTS THAT HAVE BEEN PROVEN TO GENERATE QUALIFIED PATIENTS FOR RESEARCH PROGRAMS:

Enrollment Prediction Analytics Enrollment

Appointment Scheduling

Follow-Up & Pre-Screening

Patient Referral Generation

Social Media Listening

Ad Creation & Placement

ENROLLMENT PREDICTION ANALYTICS

IN-SITE WILL COMPILE INFORMATION FROM MULTIPLE DATA POINTS, INCLUDING OUR PATIENT IDENTIFICATION SYSTEM, SOCIAL MEDIA, KEYWORD SEARCHES, AND REPORTS FROM 3RD PARTY CLINICAL TRIAL ADVERTISEMENT VENDORS TO PREDICT A NUMBER OF ENROLLED SUBJECTS PER SITE PER MONTH.

2,000 referrals

70-80 patients

National Multi-Site Campaign

ENROLLMENT PREDICTION ANALYTICS

50 referrals

2-3patient

s

Regional Multi-Site Campaign

Single Site Campaign600 referrals

20-25patient

s

DIGITAL MEDIA LISTENING

BEFORE LAUNCHING ANY DIGITAL RECRUITMENT CAMPAIGN, IN-SITE WILL CONDUCT IN-DEPTH RESEARCH ON THE TYPES OF CONVERSATIONS YOUR DESIRED PATIENT POPULATION IS PARTICIPATING IN ON SOCIAL MEDIA, BLOGS, FORUMS, AND IN THEIR SEARCHES. WE WILL LEVERAGE THIS DATA TO CREATE ADVERTISEMENTS THAT WILL APPEAL TO THIS AUDIENCE AND ENCOURAGE PARTICIPATION IN YOUR RESEARCH PROGRAM.

AD CREATION & PLACEMENT

AFTER CREATING APPEALING ADVERTISEMENTS AND SUBMITTING FOR IRB APPROVAL, IN-SITE WILL PLACE TARGETED ADVERTISEMENTS ON THE MOST EFFECTIVE CHANNELS FOR YOUR INDICATION.

PATIENT REFERRAL GENERATION

IMMEDIATELY AFTER YOUR CAMPAIGN’S ADVERTISEMENTS BEGIN CIRCULATING ON NUMEROUS DIGITAL VENUES, WE WILL BEGIN RECEIVING PATIENT REFERRALS FROM 100% ‘OPT-IN’ SIGN-UPS ON YOUR CAMPAIGN’S UNIQUE PATIENT APPLICATION. CONTACT INFORMATION IS STORED IN A SECURE DATABASE AND ACCESSIBLE IN REAL-TIME. THE REFERRAL IS THEN PLACED INTO OUR PROPRIETARY PATIENT TRACKING SYSTEM.

FOLLOW UP & PRE-SCREENING

A DEDICATED TEAM FROM IN-SITE’S IN-HOUSE CALL CENTER WILL BE RESPONSIBLE FOR FOLLOW-UP WITH ALL PATIENT REFERRALS THAT ARE CREATED. OUR RECRUITMENT SPECIALISTS WILL CONDUCT AN IRB-APPROVED PHONE SCREEN TO DETERMINE ELIGIBILITY FOR PARTICIPATION. IF ELIGIBLE, THE REFERRAL WILL BE SCHEDULED FOR AN APPOINTMENT AT YOUR SITE.

SCHEDULED SCREENING

DNQ

APPOINTMENT SCHEDULING

IN-SITE’S RECRUITMENT SPECIALISTS WILL ADAPT TO ANY SCHEDULING SERVICE OR PROCEDURE USED AT ANY SITE, INCLUDING GOOGLE CALENDAR, ACUITY SCHEDULING, SCHEDULEONCE, AND MORE.

ENROLLMENT

IN-SITE WILL ONLY SEND QUALIFIED LEADS TO YOUR SITE(S), BASED ON YOUR PROTOCOL’S INCLUSION/EXCLUSION CRITERIA AND PRE-SCREENING CONDITIONS. FROM THESE APPOINTMENTS, YOU CAN EXPECT TO SEE SUBJECTS RANDOMIZED INTO YOUR PROGRAM!• Risk-Free Enrollment:

• IN-SITE offers a pay-per-patient-randomized model to eliminate risk for sites and sponsors…Only pay when a patient is successfully enrolled within theprotocol of your program!

Randomized

Additional RecruitmentCapabilities & Services

CAPABILITIES & SERVICESADDITIONAL RECRUITMENT

IN ADDITION TO OUR STANDARD RECRUITMENT SERVICES, IN-SITE IS CAPABLE OF AIDING PROGRAMS IN THE FOLLOWING AREAS:

Multi-Site Management

Global NHV Recruitment

Rare Disease Recruitment

MULTI-SITE MANAGEMENT

POTENTIAL PATIENT CONTACT INFORMATION IS AUTOMATICALLY SORTED BY LOCATION, MAKING IT EASY TO MANAGE PATIENT REFERRALS FROM MULTIPLE LOCATIONS AND SEND THEMTO THE CORRECT SITE IN YOUR PROGRAM.

POTENTIAL PATIENT INPUTS DATA

SITE A

SITE B

SITE C

INFORMATION FORWARDED TO APPROPRIATE SITE

GLOBAL NVH RECRUITMENT

WHILE WCCT GLOBAL IS THE PREMIERE CRO IN RECRUITING NORMAL HEALTHY VOLUNTEERS IN THE SOUTHERN CALIFORNIA REGION, IN-SITE’S CAPABILITIES ALLOW WCCT GLOBAL TO RECRUIT NORMAL HEALTHY VOLUNTEERS FROM ANY REGION IN THE UNITED STATES FOR PHASE 1 STUDIES.

IN-SITE Process for Global NHV Recruitment:

• Create visually-appealing advertisements with trial-specific information for use on Web, Print, & Digital Radio

• Place targeted advertisements directed at Healthy Volunteers in any US region

• Coordinate with site to identify schedule for study visits

• Conduct phone screen with potential volunteers

• Schedule study visits in real-time using Cloud-Based scheduling

GLOBAL NVH RECRUITMENT

1 Month Recruitment Campaign:• Delivered targeted advertisements to over 5,500

viewers online• Generated 600 potential study subject referrals• Contacted over 500 potential study subjects• Scheduled over 70 Appointments• Enrolled over 30 subjects = 5% Enrollment Rate

Referrals Contacted Appointments

Enrolled

600 500+ 70+ 30+

MATCHING STUDY CONDUCTED IN NEW YORK CITY LOOKING FOR NORMAL HEALTHY VOLUNTEERS AGES 13-21 TO PARTICIPATE AS CONTROL GROUP FOR AN ADOLESCENT RESPIRATORY & MENTAL HEALTH EVALUATION FOLLOWING THE ATTACKS OF 9/11

RARE DISEASE RECRUITMENT

BECAUSE OF LOW PREVALENCE AND SCATTERED PATIENT POPULATIONS, RECRUITING PATIENTS FOR RARE DISEASES IS ESPECIALLY DIFFICULT. HOWEVER, IN-SITE OFFERS A NUMBER OF SERVICES TO HELP RECRUIT PATIENTS FOR EVEN THE MOST RARE DISEASES.

Rare Disease Recruitment Strategies:

• Study-specific, multilingual websites

• Creation of online patient communities for patient/caregiver interaction and engagement

• Targeted keyword and social media

STATISTICS & ANALYTICSIN-SITE PERFORMANCE

• 95% of IN-SITE patient referrals generated by digital advertising in any recruitment campaign

• 93% of IN-SITE patient referrals generated within first 60 days of recruitment campaign or less

• 97% overall retention rate• Avg. 67% of all patients enrolled for entire program

were through IN-SITE generated patient referrals• Improves retention and engagement rates by up to

37% • 100% of patient referrals are followed up with within

48 hours• Call Center can schedule up to 100 appointments in a

single day

BY THERAPEUTIC AREAPATIENT RECRUITMENT SUCCESS

IN-SITE CAN BE USED FOR ANY PATIENT POPULATION

ASTHMA/ALLERGY

OPHTHALMOLOGYIMMUNOLOGY

INFECTIOUS DISEASENEUROLOGY

CV/METABOLIC

ONCOLOGYNEPHROLOGY

HEPATOLOGYETHNOBRIDGING