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2013 Department of Surgery Annual Report Improving Lives Together

Improving Lives Together

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2013 Department of Surgery

Annual Report

Improving Lives Together

Table of Contents

Message from the Chair 2

Division of Cardiac Surgery 3

Division of General Surgery

5

Division of Neurosurgery

8

Division of Orthopaedic Surgery 9

Division of Otolaryngology - Head & Neck Surgery

13

Division of Pediatric Surgery 15

Division of Plastic Surgery 17

Division of Surgical Research 19

Division of Thoracic Surgery 22

Division of Urology 23

Undergraduate Medical Education 25

Postgraduate Surgical Education 27

Graduate Program 29

Message from the Chair

Strategic planning was the major focus for our department in 2013. Through many meetings filled with thoughtful and positive discussion we felt it was important to review our mission and vision statements. I‘m pleased to say that 2013 saw the emergence of our new mission statement, ‗improving lives together‘. Armed with this new idea we were able to forge ahead with our department strategic plan. The process of developing such a plan is a lengthy one. It takes many minds and a full commitment to the goal. After substantial collection and interpretation of data we were able to compile the information and put a detailed strategy map in place. This map will allow us to form working groups to address each strategy and objective as well as measure set targets. With faculty and staff participation we will see department members build, collaborate and lead the department into the next 3 to 5 years. 2013 saw a continued commitment to academics when members attended the Royal College ICRE meeting in Calgary. A lot of great information came out of the two day conference which focused on educational outcomes,

inspiring residents and improving care. Plenary speakers addressed important elements of residency training, including competency-based education. We also took a look at the resident duty hours report and recommendations from the National Steering Committee. This topic will continue to be under debate but a flexible approach to RDH regulation seems to be the most widely accepted. Within the department, we had another successful education-al retreat held in November at the Lister Centre. Guest speakers Alister Browne from UBC and Vic Adamowicz from the U of A delivered interesting talks regarding distributive justice, as well as economic factors and public preference in resources. It was wonderful to see our many residents in attendance and engaged in discussion on these topics. On May 10th we celebrated the 25th Anniversary of Tom William‘s Surgical Research Day. Alumnus Dr. Garth Warnock joined us as our distinguished visitor and guest judge. That evening, at the Surgical Awards Dinner, we celebrated the end of the academic year and honoured our members, scholarship

recipients, and graduating graduate students and chief residents.

I continue to be proud of the accomplishments of our faculty, staff and learners and look forward to continued collaboration in all areas of the department. I anticipate many new ideas and initiatives to come out of the strategic plan working groups and thank members for their work and dedication to the department.

Douglas M Hedden, MD FRCSC Walter Stirling Anderson Professor and Chair, Department of Surgery, Faculty of Medicine & Dentistry, University of Alberta

Dr. Douglas Hedden

3

2013 was another year of significant change for the Division of Cardiac Surgery. Dr. Arvind Koshal retired after 22 years in Edmonton – 19 as Head of the Division – during which time he was one of the major drivers for the creation of the Mazankowski Alberta Heart Institute. A number of events were held to commemorate Dr. Koshal‘s career culminating in the creation of the Dr. Arvind Koshal Cardiac Surgery Advancement fund which will help the division, and the MAHI, fulfill its mandate to provide the very best in patient care through innovation in clinical care, research and education.

Dr. Darren Freed joined the division bringing both excellence in surgical care along with his research program focused on optimizing marginal cardiac donors. Darren‘s research fits well with Dr. Jayan Nagendran‘s work with ex-vivo lung perfusion and offers real hope to those waiting thoracic surgery transplantation – a strength of the division.

After 8 years as Residency Program Director, Dr. Rod MacArthur handed over this critical role to Dr. Shaohua Wang. The division thanks Rod for his tremendous work in this role and welcomes Shaohua to this important position.

Ongoing population growth in Alberta has led to long, and growing, wait lists for cardiac surgery as well as many other procedures. Calgary and Edmonton were successful at getting additional resources to increase surgical volumes in 2014.

Construction has been completed on a new hybrid operating room, and 6 more CVICU beds were finished. After many years of overcrowded and substandard Pediatric ICU facilities the government announced $57 million to develop a new pediatric cardiac ICU on the 6

th floor of the

MAHI as well as a complete redevelop-ment of the general systems PICU and NICU.

Awards & Achievements

Darren Freed: Mentor-Mentee Award, The Transplantation Society Section of Cardiac Surgery Resident Teaching Award (Manitoba)

Ivan Rebeyka: Queen's Diamond Jubilee Medal Program Chair - AATS/STS Congenital Surgery Symposium

Steven Meyer: Teacher of the Year Award (three years consecutively)

Jeevan Nagendran (senior resident): American Association of Thoracic Surgeons - C. Walton Lillehei Award Winner - International

Jeevan Nagendran: Canadian Diabetes Association – Doctoral Research Student-ship -National Canadian Society of Transplantation – Cardiac trainee award - oral presentation - 1st place - National

Jeevan Nagendran: George R. Graham Memorial Award in Surgery – Department of Surgery, University of Alberta Jeevan Nagendran—Cardiac Science Research Day - Basic Sci-ence presentation -1st place (Local)

Divisional Director: Dr. David Ross

Program Director: Dr. Rod MacArthur

Cardiac

Surgery

Jeevan Nagendran: Tom Williams Surgical Research Day – Basic Science oral presenta-tion – 1st place (Local)

Jeevan Nagendran: Shab Puri Resident Award in Cardiac Surgery

Grants

Energy metabolism in the newborn heart. Lopaschuk GD, Rebeyka IM, Jaswal J, Jhangri G: Canadian Institutes of Health Research. ($160,724/yr total group grant, 2012-2016

2013-2018: Canadian Institutes of Health Research: $13,850,000. Canadian National Transplant Research Program: Increasing Donation and Improving Outcomes. PIs: West, Caulfield, Hebert, Humar, Knoll, Levings, Mital, Roy, Shultz and Shapiro. Co-applicant along with 94 others. (Darren Freed)

2013-2016: University of Alberta Hospital Foundation: $450,000. Recruitment/start-up funds (Darren Freed)

2013: University of Manitoba, Department of Surgery: $15,000. Determining optimal reperfusion of hearts from donors after cardiocirculatory death. (Darren Freed)

2013-2016: Alberta Innovates Health Solu-tions, Collaborative Research and Innovation Opportunities Program Grant. $750,000. The Human Explanted Heart Program (HELP) at the Mazankowki Alberta Heart Institute: A Translational Bridge for Cardiovascular Medicine. Co-applicant with Gavin Oudit and 14 others. (Darren Freed) 2012-2014 Central Aortic Pressure Study: in-human validation of a technique for measuring central aortic hemodynamics with peripheral arterial waveforms. PIs: Drs. Barry Finegan, M.S.McMurtry, M.K.Stickland, J.O.Hahn Co-Is: Drs. S.Wang, R.MacArthur, J.Nagendran, A.Koshal, N.Ghorpade ($107,000) 2013-2016 : Canada Africa Heart Project, CIDA grant for development of the Cardiac Sciences Program at the AGA KHAN University Hospital, Nairobi, Kenya. Roderick MacArthur $500,000

Publications

Publications: 48 Clinical trials: 4 Book chapters: 1

5

The Division of General Surgery at the University of Alberta continues to work hard, guided by its vision – ―Working together toward the common goal of providing excellent patient care while continuing and strengthening a tradition of teaching and research‖. The Division of General Surgery is the largest division in the Department of Surgery with close to 100 faculty members. Each member is committed to the common goal of excellence in clinical care delivery, education and research. Due to this commitment, tremendous innovation has taken place within the division. The development of acute care services at the University of Alberta and Royal Alexandra Hospitals has contributed greatly to the management of the acutely ill and injured patient, ensuring care is given in a timely fashion. The Centre for the Advancement of Minimally Invasive Surgery (CAMIS) has brought minimally invasive surgery to a new level. Under the careful watch of Dr. Dan Birch, the centre has developed a world-class curriculum used for the training of surgeons from several surgical specialties. CAMIS has established a mentoring program, advancing surgeons‘ skills at a local, provincial, and national level. With the recruitment of Dr. Haili Wang and Dr. Anna Borowiec, a formal collaborative clinic has been established with members from the Division of Gastroenterology to service the Inflammatory Bowel Disease population. Established programs within the division have continued to flourish such as hepatobiliary and pancreatic surgery, transplantation, trauma,

surgical oncology, endocrine surgery, gastroin-testinal surgery, head and neck surgery, vascular surgery, and breast surgery. The division is wide spread, operating within the Edmonton Zone at the University of Alberta Hospital, the Royal Alexandra Hospital, Misericordia Community Hospital, Grey Nuns Community Hospital, Sturgeon Community Hospital and the Ft. Saskatchewan Community Hospital. Faculty members are also present in Grande Prairie, Lethbridge, Ft. McMurray and Lloydminster.

Education Education is always a priority within the division and its members provide countless hours of teaching to both undergraduate and post-graduate students. Dr. Kamran Fathimani is new program director for residency training in General Surgery. The past program director is Dr. Dan Schiller whose work was greatly appreciated. A dedicated rural training stream has been developed within the residency training program and is running well, with the first resident currently training in Grande Prairie. A resident retreat is held annually. Dr. Arnold Coran from the University of Michigan was the guest speaker for the 2013 retreat held in Jasper. Dr. Coran‘s discussion focused on Pediatric Surgery.

Research A strong culture in surgical research has all faculty members a part of this important task. The

Program Director: Dr. Kamran Fathimani

Divisional Director: Dr. David Williams General

Surgery

6

division continues its proud and strong tradition of both basic and clinical science research. Members of the division hold 25 million dollars of support in 60 grants.

Areas of basic research interest include translational research on inflammatory mediators, genetic mutational analysis as related to lymphangiogenesis in endocrine malignancies, islet cell transplantation, hepatitis C, tissue cryopreservation, and intestinal is-chemia. Clinical research is also strong in the division, with several grants received looking at surgery in the elderly.

Promotion & Recruitment 2013 - 2014

With the growth of the division, many promotions and recruitments took place. Appointed Clinical Lecturer: Dr. Athena Bennett Dr. Anna Borowiec Dr. Iftikhar Ahmad Dr. Adrian Indar Appointed Associate Professor with Tenure: Dr. Ioana Bratu Dr. Dan Schiller Appointed Clinical Professor: Dr. Harold Chyczij Appointed Clinical Assistant Professor: Dr. David Olson

Resident Research Day 2013 At the division‘s 2013 Resident Research Day, visiting professor and judge, Dr. Rebecka Myers presented City Wide Rounds on Conjoined Twins: A Tour de Force in Teamwork. Dr. Meyers is a Professor of Surgery at the University of Utah School Of Medicine, Primary Children's Medical Center, Salt Lake City, Utah.

Resident Research Day Awards 2013 Basic Science:

1st - David Al-Adra Host APCs, not Vascular Endothelium, Control Indirect Rejection by CD8 T cells 2nd - Troy Perry Ileocolic Resection Recruits CD11cCD103 Dendritic Cells to the Gut and Prevents the Release of Pro-Inflammatory Cytokines in a Surgical Mouse Model 3rd - Pang Young Oncostatin M Primes Macrophage-Epithelial Cell Interactions to Lipopolysaccharide Clinical Science:

1st - Abdullah Saleh Creating an Inter-Organizational Electronic Health Record in Kibera – Challenges and Solutions 2nd - Shaheed Merani Research Productivity and General Surgical Residency – Impact of Graduate Degree Training 3rd - David (Yi Man) Ko Appendiceal Neuroendocrine Tumors - Edmonton Experience

Awards & Achievements Faculty awards

William Shandro Award for Teaching Excellence in Clinical Surgery: Dr. Kamran Fathimani David Cook Award: Dr. Jonathan White Medical Students‘ Association 2012 - 2013 Year 2 Award, Discovery Learning Preceptor of the Year: Dr. Eric Bédard

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Medical Students‘ Association 2012-2013 Year 4 Award, Discovery Learning Preceptor of the Year: Dr. Jason Bayne

New Roles Dr. Erika Haase, Program Director, Surgical Foundations Dr. Heather Cox, appointed New Clerkship Director Dr. Mary Stephens accepted the position of Site Lead, University of Alberta hospital Dr. Damian Paton-Gay accepted the position of Facility Section Head, Trauma at the Royal Alexandra Hospital Dr. Kamran Fathimani accepted the position of Program Director

Top 10 Teacher Awards 2013 Dr. Michael Chatenay Dr. Kelly Dabbs Dr. Kamran Fathimani Dr. Erika Haase Dr. Ghassan Hadi Dr. Shahzeer Karmali Dr. David Olson Dr. Cliff Sample Dr. James Stewart Dr. Walter Yakimets

Top Specially Surgery Awards 2013: Dr. Eric Bédard Dr. Ken Stewart

Resident Awards Dr. Amir Yousef Taheri 1

st Prize, 3

rd Year of Residency

RE Fraser Award for Excellence in Teaching 2013: Dr. Michael McCall

Marshall C. Hunting Award in Vascular Surgery 2013: Dr. Dana Mihalicz Suturing Competition: Dr. Yi Man (David) Ko Ultimate SAGES Resident Education Award: Dr. Jack Chiu – 1

st place

Ultimate SAGES: Dr. Andrey Vizhul – 2

nd place

CAGS Teaching Excellence 2013: Dr. Simon Turner

Grants

99 Grants totaling $30,886,235.51

Publications, Reviews & Book

Chapters Conference proceedings (2) Original research journal article (130) Book chapter (9) Other (4) Poster (2) Abstract (32) Review journal article (5) Editorial (1) Commentary (1) PODcast (20)

8

The Division of Neurosurgery has 13 members; three full time pediatric Neurosurgeons and 10 adult Neurosurgeons. All pediatric neurosurgery is located at the University of Alberta Hospital. The adult neurosurgery division is split between the Royal Alexandra Hospital (three surgeons) and the University of Alberta Hospital (seven neurosurgeons).

3T intraoperative MRI

After almost a decade of planning and construc-tion, the intraoperative MRI (iMRI) is now fully operational and allows for not only anatomic imaging but also functional MRI (fMRI) and diffusion weighted imaging and tractography (DTI). The iMRI remains a highlight of the program and Edmonton remains one of the few neurosurgical centers in the country with a 3T intraoperative MRI.

Education

All members of the division participate in Undergraduate Medical Education contributing both to Discovery Learning and Gilbert Scholar

programs. There are seven residents enrolled in the Residency Program. The fellowship program continues to expand. There are three formal fellowship programs available. The spine fellowship program continues to recruit and train spine fellows. There is now a pediatric neurosurgical fellowship, as well as an epilepsy surgery fellowship.

Research

Most members of the division are involved in either collaborative research or self-directed research. The division is involved in over 40 separate research projects and protocols with total grant revenue of $1.15 million. The commit-ment to research is exemplified in the publica-tion record of the division. There were 61 papers published of which 32 were peer-reviewed. There were 2 book chapter authored. The Division continues to support the academic mission within the Department of Surgery and will continue to support both collaborative and independent research projects.

Neurosurgery

Divisional Director: Dr. B Matt Wheatley

Program Director: Dr. Cian O’Kelly

Blondel from Marseille, France along with local faculty, presented several talks on areas of their research interests. Dr. Reggie Hamdy from Montreal was the 2012 Brian Greenhill Visiting Lecturer in Pediatric Orthopaedics at the Annual Peds Day in Novem-ber. There were several other social events that helped build resident and staff camaraderie. These includ-ed The Annual Resident Golf Tournament and Farewell to the Chiefs Party, the welcome to the new residents‘ party at Hawrelak Park and the Christmas Party at the Mayfair Golf and Country Club. On the Research front, the division has continued to be very productive with over 100 publications and presentations. Many of the publications were in high impact specialty and subspecialty journals and the presentation were at the local, national and international level. The division is excited about the new clinical research space that has been set aside in the Clinical Sciences building. The Clinical Orthopaedic Research (CORe) group has been formed as a collaboration between orthopaedic surgery and physical therapy. It is hoped that this new space will bring together the various partners interested in clinical musculoskeletal research.

Awards & Honours Staff Dr. John McIvor and Dr. Beth Pedersen were awarded the Orthopaedic Surgery Teacher of the Year Award for 2013. Dr. Lauren Beaupre (Steering Committee - Bone and Joint Canada) received the

9

In 2013, the Division of Orthopaedic Surgery had 42 active members. Dr. Tom Greidanus retired after many years of active clinical practice. There were two new additions to the division: Dr Jeff Toreson (oncology and trauma) and Dr. Eric Huang (adult and paediatric spine surgery). There were 21 residents in the orthopaedic training program. All four of the chief residents passed their Royal College Exams in 2013. There were fellows in Trauma, Sports Medicine, Spine and Pediatrics. All faculty members were involved in the education of medical students at various levels of training including the Gilbert Scholar and Discovery Learning programs, the MSK block for pre-clinical students and the clinical rotations of the fourth year students. There were 60 local & national elective students. The division had another very successful Resident Retreat to Jasper in January with lively debates on Current Controversies in Orthopaedics. Dr. Richard McLeod from Kamloops was our guest speaker. The Annual Alberta Orthopaedic Resident Research Day was held in April. This was the first time in 39 years that the University of Calgary declined to have a combined research day. Dr. Kishore Mulpuri from the University of British Columbia was the visiting adjudicator. Many excellent resident projects were presented. The division was honoured to host the CFBS Traveling Fellows as they made their tour across Canada in June. Dr. Stephane Cherix from Lausanne, Switzerland and Dr. Benjamin

Orthopaedic

Surgery

Divisional Director: Dr. Edward Masson

Program Director: Dr. Angela Scharfenberger

Institute for Musculoskeletal Health and Arthritis Knowledge Translation Prize in 2013. Dr. Nadr M Jomha: International Cartilage Repair Society Fellow .

Students Dr. Khaled Al-Manssori: University of Alberta Resident Research Day, ROTA Resident Outstanding Teacher Award. Dr. Khaled Al-Abassi: University of Alberta Resident Research Day, Best Basic Science Paper. Dr. Colleen Weeks: University of Alberta Resident Research Day, Best Clinical Research Paper. Dr. Armin Badre: University of Alberta Resident Research Day, Best Literature Review. Dr. Ben Herman was awarded the Cooper Johnston Memorial Scholarship. Dr. Khaled Almansoori was awarded the Dr. Hastings Mewburn Postgraduate Scholarship in Orthopaedic Medicine. Roger Croutze: University of Alberta Depart-ment of Surgery Research Day, Basic Science Poster Presentation 2nd place.

Elise Watkins: CIHR Banting and Best Graduate Award, U of A president award, WCHRI award. Chris Woloschuk: Queen Elizabeth II Scholarship. Alan Richter: PT department research award 2013. Eric Chalmers: WCHRI, AITF, TD Interdisciplinary Award.

Key Research Publications Research continued to grow and expand as outlined in the 2013 Research Newsletter available online at www.uofaweb.ualberta.ca/orthopaedicsurgery

Spine Research Chen W, Lou E, Zhang P, Le L.H: Reliability of assessing the coronal curvature of scoliosis by using the center of lamina method on ultrasound images, Journal of Children‘s Orthoapedic, 7:521-529, 2013. Nguyen KC, Le LH, Tran T, Lou E: Excitation of Ultrasonic Lamb Waves Using a Phased Array System with two Array Probes: Phantom and In vitro Bone Studies, Ultrasonics Special Issue, 2013 Doi: 10.1016/j.ultras.2013.08.004, 2013. Evans K, Lou E, Faulkner G: Optimization of a Low Cost Force Sensor for Spinal Orthosis Applications, IEEE Trans-actions on Instrumentation & Measurement, 62(12):pp.3243-3250, 2013. Li HJ, Le LH, Sacchi M, Lou E: Ultrasound Imaging of Long Bone Fractures and Healing with Split-Step Fourier Imaging Method, Ultrasound in Medicine and Biology, 39(8): pp.1482-1490, 2013. Chan A, Lou E, Hill D: Review of Current Technologies and Methods Supplementing Brace Treatment in Adolescent Idiopathic Scoliosis, Journal of Children‘s Orthopaedic, 7(4):309-316, 2013. Wong AY, Parent EC, Kawchuk GN Reliability of 2 ultrason-ic imaging analysis methods in quantifying lumbar multifidus thickness. J Orthop Sports Phys Ther. 2013 Apr;43(4):251-62.. Epub 2012 Dec 7. Wong AY , Kawchuk G , Parent E , Prasad N, "Within- and between-day reliability of spinal stiffness measurements obtained using a computer controlled mechanical indenter

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Program Director: Dr. Angela Scharfenberger

gorizing external deformity in scoliosis. Spine J. 2013 Oct 17. pii: S1529-9430(13)01572-6. [Epub ahead of print].

Trauma Research

Chow R, Beaupre LA, Rudnisky CJ, Otto D, Clark M: Occupational risk in orthopaedic surgery. Is the use of fluoroscopy hazardous to your vision? Am J Orthop (2013) 42(11):505-10. Wilson DM, Robertson S, Jones CA, Majumdar SR, John-ston DWC, Beaupre LA: Barriers and facilitators to an outreach rehabilitation program delivered in nursing homes after hip fracture surgical repair. Adv Aging Res PP. 37-42, Pub. Date: February 28, 2013. DOI: 10.4236/aar.2013.21005. Rashiq S, Vandermeer B, Abou-Setta AM, Beaupre LA, Jones CA, Dryden DM: Efficacy of supplemental peripheral nerve blockade for hip fracture surgery: Multiple treatment comparison Can J Anasthes Article first published online: Jan 2013 | DOI 10.1007/s12630-012-9880-8. Menon M, Jomha NM. Regional Anaesthesia in the Patient at Risk for Acute Compartment Syndrome: Con (Acute Compartment Syndrome: Caution Ahead) ASRA News – American Society of Regional Anaesthesia and Pain Medi-cine. May 2013, pp 4 – 7.

11

in individuals with and without low back pain.", Manual therapy,18(5):395-402, 18(5) (2013) Schofield JS , Parent EC , Lewicke J , Carey JP , El-Rich M , Adeeb S,"Characterizing asymmetry across the whole sit to stand movement in healthy participants.", Journal of biomechanics [Epub Ahead of Print] (2013). Schofield J , Parent E , Lewicke J , Carey JP , El-Rich M , Adeeb S, "Leg Dominance May Not be a Predictor of Asymmetry in Peak Joint Moments and Ground Reaction Forces During Sit to Stand Movements.", Journal of ap-plied biomechanics [Epub ahead of print] (2013). Wong AY , Parent EC , Funabashi M , Stanton TR , Kawchuk GN, "Do various baseline characteristics of transversus abdominis and lumbar multifidus predict clinical outcomes in nonspecific low back pain? A system-atic review.", Pain [Epub ahead of print](2013). Wong AY, Parent EC, Funabashi M, Kawchuk GN. Do Changes in Transversus Abdominis and Lumbar Multifidus During Conservative Treatment Explain Changes in Clinical Outcomes Related to Non-specific Low Back Pain? A Systematic Review.J Pain. 2013. Nov 1. pii: S1526-5900(13)01317-5. [Epub ahead of print].

Komeili A, Westover LM, Parent EC, Moreau M, El-Rich M, Adeeb S. Surface topography asymmetry maps cate-

Guitton TG, Ring D, Menon M. etc.* Diagnosis of Union of Distal Tibia Fractures; Accuracy and Interobserver Re-liability. Injury, 44(8): 1073-5, 2013. * = As part of the Sci-ence of Variation Group (SOVG).

Knee Research

Swami VG, Mabee M, Hui C, Jaremko JL. Three-dimensional intercondylar notch volumes in a skeletally immature pediatric population: a magnetic resonance imaging-based anatomic comparison of knees with torn and intact anterior cruciate ligaments. Arthroscopy. 2013 Dec; 29(12): 1954-62. Swami V, Cheng-Baron J, Hui C, Thomson R, Jaremko J. Reliability of estimation of pediatric ACL attachment loca-tions from 3D knee reconstruction based on routine clinical MRI. American Journal of Sports Medicine. 2013 June; 41(6): 1319-1329.

Arthroplasty Research

Powell PJ on behalf of the Canadian Arthroplasty Society: The Canadian Arthroplasty Society's Experience with Hip Resurfacing Arthroplasty: An Analysis of 2773 Hips. Bone Joint J (2013) 95-B:1040-1044. Beaupre LA, Manolescu A, Johnston DWC: Five-Year Outcome of Ceramic on Ceramic Bearing versus Ceramic on Crossfire® Highly Cross-Linked Polyethylene Bearing in Primary Total Hip Arthroplasty: A Randomized Trial of 92 Subjects 60 Years of Age or Younger. J Arthroplasty. (2013) 28:485-489. Alhaideb A, Muir SW, Huckell J, Alsaleh KA, Johnson MA, Johnston DWC, Beaupre LA: Inter-observer reliability of the radiographic assessment of cement fixation in total hip arthroplasty. Eur J Orthop Surg Traum Article first pub-lished online: 18Oct2012 | DOI 10.1007/s00590-012-1108-7.

Upper Extremity Research

Weeks C, Begum F, Adeeb S, Beaupre LA, Carey J, Bouli-ane M: Restoration of Medial Column Enhances Fracture Fixation Stability in Proximal Humeral Fractures: A Cadav-eric Study. J Shoulder Elbow Surg (2013) 22 (11):1552-1557| DOI doi.org/10.1016/j.jse.2013.02.003 (IF 2.32). Bouliane M, Beaupre L, Ashworth N, Lambert R, Silveira A, Sheps D: Suprascapular Nerve Injury During Arthro-scopic Superior Labral Repair: A Prospective Evaluation. Knee Surg Sports Traumatol Arthrosc Article first pub-lished online: Jan 2013 | DOI 10.1007/s00167-013-2415-1 (IF 2.67). Zhao H, Herman B, Adeeb S, Sheps D, El-Rich M: Investigation of the geometries of the coronoid process and the fibularallograft as a potential surgical replacement. Clin Biomech (2013) 28:626-634.

Paul R, Chan R: Nonsurgical Treatment of Elbow Stiffness J Hand Surg Am (2013) 38(10):2002-4. Furey MJ, Sheps DM, White NJ, Hildebrand KA. A retrospective cohort study of displaced segmental radial head fractures: is 2 mm of articular displacement an indication for surgery? Journal of Shoulder and Elbow Surgery. 2013 May; 22(5): 636-41. Bouliane MJ, Chan H, Kemp K, Glasgow R, Lambert R, Beaupre LA, Sheps DM. The intra- and inter-rater reliability of plain radiographs for Hill–Sachs and bony glenoid le-sions: evaluation of the radiographic portion of the instabil-ity severity index score. Shoulder & Elbow. 2013 January; 5(1): 33-8.

Joint Regeneration Research Publications

Croutze R, NM Jomha, H Uludag and AB Adesida. Matrix forming characteristics of inner and outer human meniscus cells on 3D collagen scaffolds under normal and low oxygen tensions. BMC Musculoskeletal Disorders 14, no. 353, 2013. Matthies N, A Mulet-Sierra, NM Jomha, and A Adesida. Matrix formation is enhanced in co-cultures of human meniscus cells with bone marrow stromal cells. J. Tissue Engineering & Regenerative Medicine 7(12), 965-973, 2013. Chowdhury A, LW Bezuidenhout, A Sierra-Mulet, NM Jomha, AB Adesida. Effect of interleukin-1 beta treatment on co-cultures of human meniscus cells and bone marrow mesenchymal stromal cells. BMC Musculoskeletal Disorders. 2013, 14:216 doi:10.1186/1471-2474-14-216. Published July 22, 2013. Abazari A, NM Jomha, JAW Elliott, LE McGann. Cryopreservation of articular cartilage. Cryobiology, 66(3): 201-209, 2013. Yu H, K Al-Abbasi, JAW Elliott, LE McGann, NM Jomha. Clinical efflux of cryoprotective agents from vitrified human articular cartilage. Cryobiology 66, 121-125, 2013. Sanghani A, M Chimutengwende-Gordon, A Adesida, W Khan. Applications of stem cell therapy for physeal injuries. Curr Stem Cell Res Ther 2013, 8(6):451-455. Haddad B , AH Pakravan, S Konan, A Adesida, W Khan. A systematic review of tissue engineered meniscus: cell-based preclinical models. Curr Stem Cell Res Ther 2013, 8(3):222-231. Haddad B, S Konan, A Adesida, WS Khan. A systematic review of tissue engineered meniscus and replacement strategies: preclinical models. Curr Stem Cell Res Ther 2013, 8(3):232-242.

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The Division of Otolaryngology head and neck surgery had an excellent and productive 2013 academic year. The highlight of the divisional academic activities was the divisional Resident Research Day on May 3, 2013. The invited speaker was the distinguished Dr. Ron Mitchell, Professor of Otolaryngology and Pediatrics and Chief of Pediatric Otolaryngology, UT South-western Medical Center, Children‘s Medical Center Dallas.

Education Two excellent residents decided to join our program this year and these were Dr. Graeme Muholland and Dr. Andre Isaac. Fellowship programs continued to attract excellent candidates. Hani Almarzouki, accepted the advanced head and neck oncology and reconstruction fellowship position and Dr. Marie Bussieres accepted the rhinology and skull base fellowship position.

Awards & Achievements Dr. Khalid Ansari, Department of Surgery Top 10 Teacher of the Year Award.

Dr. David Côté: - Golden Apple Award For Best Academic Teacher of the Year.

- Outstanding Reviewer award.

- 2nd place - Best Research Poster, Clinical.

- 2nd place - Best Research Project, Clinical. Canadian Society of Otolaryngology-Head & Neck Surgery Poliquin Resident Research Competition. Association Between Allergic Rhinitis and Asthma in Northern Alberta: A Population-based Study **Principal Investigator on Resident Project. First Place. Best Resident Research Project. Dr. Allan Ho: - Gilbert Scholar's Preceptor of the Year Award. - Grey Nuns Excellence in Teaching Award 2012-2013. Dr. Suresh Nayar, Clinical Excellence Award. Dr. Dan O‘Connell, Top Reviewer - Journal of Otolaryngology - Head & Neck Surgery. Dr. Vince Biron, Tom Williams Research Day - 2nd Prize, Clinical Research - Surgical versus Ultrasound Guided Drainage of Deep Neck Space Abscesses. Dr. Hadi Seikaly: - Alberta Society of Otolaryngology Head and Neck Surgery Annual meeting - Best Scientific Project 2013. V. Biron - Molecular Prognostica-tion of Survival in Oropharyngeal Squamous Cell Carcinoma.

Otolaryngology

H & N Surgery

Divisional Director: Dr. Hadi Seikaly

Program Director: Dr. Khalid Ansari

- 1st place, 4th Annual Surgical Foundations Research Day.

- NOMINATED Covenant Health Mission Awards 2013.

- Champion of Care Award. Dr. Johan Wolfaardt, Award of Excellence, Alberta Dental Association and College. Dr. Erin Wright , Top 10 Teacher - Specialty Surgery Department of Surgery

Publications, Reviews & Book

Chapters The research activity continued to be strong with 113 publications for the year.

Original research journal articles (40) Conference proceedings (22) Abstracts (27) Posters (13) Internet publications (3) Book chapters (2) Review Journal Articles (6)

Grants The total divisional grants for the year were

$815,857.00. Manuary 2013 fund raised over $20,000.00 for the Division of Otolaryngology H&N Surgery.

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2013 Resident Research Day

15

The Division of Pediatric Surgery within the University of Alberta, Department of Surgery, includes Sub-Divisions of pediatric general surgery, pediatric neurosurgery, pediatric orthopaedic surgery, pediatric otolaryngology, pediatric plastic surgery and pediatric urology. The members of these Sub-Divisions work with other pediatric specialty groups – cardiac surgery, dental surgery, gynecology, ophthalmology, oral and maxillofacial surgery and transplant surgery – in the delivery of pediatric surgical services at the Stollery Children‘s Hospital. The members of the division of pediatric surgery continue to make significant contributions to the educational and research activities of the Department of Surgery. In order to enhance further expansion and excellence in academic activities, the members of the division of pediatric surgery have made significant contributions to future planning of pediatric surgical services. Stable and smoothly running clinical services are essential for the further enhancement of academic activities. To this end, members of the division have contributed to the Alberta Health Services 2030 planning for clinical services in division referral areas. The planning process has clearly indicated that a major expansion of resources as well as changes in the models of clinical care will be needed to meet the future care of patients. Future projections indicate a large increase in demand for clinical services from Alberta but also from provinces within Western Canada. A new Stollery Children‘s Hospital will be needed

to provide the necessary consolidated pediatric and pediatric surgical resources. Major changes to the coordination of care with regional partners and optimization of the clinical care processes within the Stollery Children‘s Hospital will be needed to meet the increased clinical demand. Additional surgeons will also be needed to provide additional forefront surgical skills and to balance the needs of clinical service and academic productivity.

Pediatric

Surgery

Divisional Director: Dr. William Cole

Pediatric heart and lung.

16

Additional resources are needed in the short-term as building a new Stollery Children‘s Hospital is a medium- to long-term project. The Stollery Children‘s Hospital, in partnership with Alberta Health Services, the University of Alberta and the Stollery Children‘s Hospital Foundation have launched many major capital projects which are likely to make a significant difference to the resources available for the delivery of clinical services and for the enhance-ment of academic activity. For example, expansions of the critical care units, operating rooms, beds and clinics are likely to provide an increased resource capacity. As the available resources increase in the short-

to medium-term there will be a need to recruit

more surgeons. Recruitment has been minimal

in recent years because of the limited available

resources. However, future recruitment is

essential in order to ensure that pediatric

surgical specialties can offer forefront care for

patients. Recruitment can also be expected to

enhance academic activity from existing

members of the division of pediatric surgery and

by recruiting surgeons who have academic

credentials and successful academic track

records.

There are many opportunities at the University

of Alberta, within Canada and beyond to build

research teams that focus on solving high

impact clinical problems.

Major research funding agencies are very

supportive of the latter approach to obtaining

new knowledge that is likely to significantly

advance health care. Another potentially

productive area of research in pediatric surgery

is in applying modern research methodologies to

gaining robust data concerning the benefits,

risks and economic outcomes of new health

technologies – including procedures and

devices. Using an evidence-based approach to

the introduction of new procedures and

technologies can be expected to significantly

enhance future developments in pediatric

surgery and surgery in general.

The University of Alberta, Division of Plastic

Surgery has had a productive year clinically and

academically in 2013. The division continues to

grow and has hired one new plastic surgeon in

2013 with two more coming on board early in

2014. Dr. Jay Zhu was first to join the group. Dr.

Zhu completed his fellowship training at the

University of British Columbia in cranio-facial

surgery and in addition, a year of fellowship

training at the University of Pittsburgh in hand

and wrist. Dr. Zhu has come back full of energy

and is already providing excellent clinical care

as well as taking a lead role in resident teaching

and recently, has become the assistant program

director. We look forward to welcoming Dr. Lisa

Korus who has completed a hand and wrist

fellowship at the Hand and Upper Limb Center

in London, Ontario, as well as a breast

fellowship in Toronto. Finally, we welcome back

Dr. Adil Ladak who has completed a breast

fellowship in Kelowna, as well as a peripheral

nerve fellowship at The Mayo Clinic.

The division would also like to sincerely thank

Dr. Gordon Wilkes for his many years of

service as our trusted divisional director. Gord

has been an outstanding leader and has guided

the division in integrity and ingenuity. On behalf

of all division members, we give Gord our most

heartfelt thanks for his service and commitment.

Dr. Jonathan Toy is continuing on in his second

year as Program Director. Dr. Jay Zhu has

joined him as an assistant program director and

together they have made some very positive

changes in our program. We currently have 16

residents in the program and are being lead very

efficiently and effectively by Drs. Toy and Zhu.

Highlights from the past year include our

Resident Research Day where Dr. Josh Wong

won the Clinical Prize and Dr. Peter Kwan won

the Basic Science prize. At the Tom Williams

Research Day this past year, Dr. Josh Wong

won the top clinical prize for his research study.

He presented this again at the International

American Society of Peripheral Nerve meeting,

where he again won the top prize in research.

Our site leaders include Dr. Ted Tredget at the

University of Alberta Hospital, Dr. Michael

Morhart, Royal Alexandra Hospital, Dr. James

Wolfli, Grey Nuns Hospital and Dr. Dave

Edwards at the Misericordia Hospital. Dr. Wolfli,

in addition has taken on the role of Plastic

Surgery lead for undergraduate medical educa-

tion and the new appointment of Quality Lead

for the division.

Dr. Gorman Louie has been increasingly active

in the AO Society, as he is currently on the

AOCMF Education Council and is an invited

lecturer and instructor internationally for this

society. Dr. Louie is also past president of the

Canadian Society of Plastic Surgery Education

Foundation and member of the Nucleus

Committee. Also of note, Dr. Blair Mehling, with

the help of Drs. James Wolfli, Paul Schembri

and the division of general surgery, have

created a new Breast Program for Northern

Alberta. This is a much needed program as this

has become the standard of care across the

country. A great deal of work has been done

17

Plastic

Surgery

Divisional Director: Dr. Jaret Olson

Program Director: Dr. Jonathan Toy

getting this set up and it is now underway as of

January 2014.

Awards

Dr. Blair Mehling, HBOC Award of Distinction

from the Hereditary Breast and Ovarian Cancer

Society of Alberta.

Dr. Jaret Olson, Top 10 Teacher Award.

Michele Gervais, Claudette Brown Award.

Research

The division has been very active in research,

and Dr. Ted Tredget‘s lab leads in this manner.

He currently has an Edmonton Civic Employees

Department of Surgery grant as well as a

Canadian Foundation for Innovation grant. He is

supervising two PhD students, two MSc students

and two post-graduate basic science students.

In addition to running his lab, he is the divisional

director for Surgical Research for the depart-

ment and research lead for the School of

Surgery. He is also currently the vice-president

of the Canadian Society of Plastic Surgeons and

American Burn Association.

The division also works in close conjunction with

Dr. Ming Chan in peripheral nerve research. We

have recently had a Master‘s student success-

fully graduate from Dr. Chan‘s laboratory and

division members are on multiple grants with

him, including a Canadian Institute of Health

Research grant, National Institutes of Health

grant, a Canadian Foundation for Innovation

grant and an Alberta Innovates Health Services

grant.

Invited Presentations:

10 + Dr. Louie contribution

Book Chapters: 1

Instructional Course Speakers at

International Meetings: 4

Visiting Professors: 1

Annual Canadian Society of Plastic Surgeons

meeting, L to R: Dr. D Edwards, Dr. J Toy, Dr. E Fung,

Dr. J Wong, Dr. K Elzinga, Dr. K Sun and

Dr. J Olson

2013 was another exciting year in the Division

of Surgical Research. In May, we once again

hosted the Edmonton Civic Employees‘

Charitable Assistance Foundation Board of

Trustees at what is now an annual breakfast.

Dr. Adetola Adesida and Dr. Bin Zheng gave

presentations on their research that had been

funded by the foundation the previous year.

The ECECAF Chair, Brenda Waluk, presented

Dr. Doug Hedden with a donation that would

go on to fund $117,914 of awards to 12

principal investigators in the 2013 competition.

This funding competition saw 19 applications

this year which saw a success rate of 63 per

cent.

Work also continues on the new Cell and Tissue Innovative Research Centre located on the 7th floor of the Li Ka Shing Building with the funding provided by a CFI award granted to Dr. Greg Korbutt. The state of the art, 10,000 sq ft facility is expected to be operational in 2014.

Tom Williams Surgical Research Day

The Tom Williams Surgical Research Day in May was another successful event. The Division of Surgical Research was the host division for this 25th annual research day. Dr. Garth Warnock, a U of A alumnus and former faculty member, was the guest speaker and judge for the day, which offered 24 oral basic and clinical science presentations, 5 basic science and 7 clinical science poster presenta-tions.

Congratulations to the prize winners:

Clinical Science Oral Presentation 1st prize – Joshua Wong

2nd prize – Vincent Biron 3rd prize – George Kurien Honorable Mention – Adam Kinnaird Poster Presentation 1st prize – Stephan van Zyl 2nd prize – Caroline Jeffery

Basic Science Oral Presentation 1st prize – Jeevan Nagendran 2nd prize – Pang Young 3rd prize – Troy Perry Honorable Mention – Joseph LaBossiere Poster Presentation 1st prize – Mahra Nourbakhsh 2nd prize – Roger Croutze

A heartfelt thank you to the judges of the

proceedings, Drs. Raymond Rajotte, Norman

Kneteman, Colin Anderson, Tom Churchill, Nadr

Jomha, Richard Fox and the distinguished judge

and Grand Rounds presenter, Dr Garth Warnock.

Surgical

Research

Divisional Director: Dr. Edward Tredget

Dr. Garth Warnock speaks at the Surgical

Awards dinner.

20

Appointments

Dr. Hamdy El-Hakim was appointed Director of Clinical Research in the department. Dr. El-Hakim has been working with NACTRC and is hopeful to have funds in place for clinical research grants in 2014.

Awards

The George R Graham Postgraduate Memorial Bursary in Surgery is awarded annually to trainees in the postgraduate program in surgery. This award is based on a combination of academic achievements including research, clinical and educational endeavors. The 2013 recipient for this award was Dr. Jeevan Nagendran, a resident in the division of cardiac surgery.

The Department of Surgery brought in over $4.5 million in grants and awards in 2013. Members of the division accounted for 41 per cent of that in the sum of $1,881,811.62. Investigators in the department were also successful in being award-ed 3 CIHR grants. Congratulations to Drs. Adetola Adesida, Todd McMullen and Babita Agrawal. Additionally, 2 CFI grants were award-ed to Tim Darsaut and Colin Anderson. Dr. Rachel Khadaroo and Dr. Todd McMullen were each successful in their applications for the Partnership for Research and Innovation in the Health System (PRIHS) awards. Dr. Khadaroo‘s project is ‗Optimizing Seniors Surgical Care – The Elder Friendly Surgical Unit and Dr McMul-len‘s project is Rectal Cancer Care Clinical Pathway‘. Todd McMullen was also successful in the AIHS Industry Partnered Translational Fund award for ‗A Monoclonal Antibody to Restore Radioiodine Sensitivity and Decrease Tumor Burden in Metastatic Papillary Thyroid Carcinoma‘. Congratulations also to James Shapiro on being named to a Tier 1 Canadian Research Chair.

Grants

The top research grants awarded to basic scientists in the division this year were: $697,183 - Dr. Adetola Adesida from CIHR for ―Knee Meniscus Reconstruction Using Mesen-chymal Stem Cells‖. $344,445.62 – Dr.Greg Korbutt from JDFI for ―Encapsulation of neonatal porcine islets for clinical transplantation‖. $313,199 – Dr. Colin Anderson from CFI for ―Visualization of Transplant Biology‖ $159,984 – Dr. Babita Agrawal from CIHR for ―New dual-mode antiviral agents for the treatment of hepatitis C virus infection‖. $150,000 – Dr. Greg Korbutt from NCESCN for ―Development of GPM E-Learning courses for GMP compliant cell therapy manufacturing facilities‖. $75,000 – Dr. Colin Anderson from the Canadi-an Diabetes Association for ―Generation of chimerism and donor specific tolerance for islet transplantation‖.

Edmonton Civic Employees’ Charitable Assistance Foundation breakfast (L to R: Dr.

Hedden, Dr. Tredget, Ms. B Waluk).

21

$50,000 – Dr. Adetola Adesida from University

of Calgary for ―Evaluate the effects of hypother-

mic storage on meniscal allograft viability‖.

Publications - Basic Scientists

Croutze R, Jomha N, Uludag H, Adesida A. Matrix

forming characteristics of inner and outer human menis-

cus cells on 3D collagen scaffolds under normal and low

oxygen tensions. BMC Musculoskelet Disord.2013 Dec

13;14 (1):353.doi: 10.1186/1471-2474-14-353

Sanghani A, Chimutengwende-Gordon M, Adesida A, Khan W. Applications of stem cell therapy for physeal injuries. Curr Stem Cell Res Ther. 2013 Nov;8(6):451-5.

Chowdhury A, Bezuidenhout LW, Mulet-Sierra A, Jomha NM, Adesida AB. Effect of interleukin-1β treatment on co-cultures of human meniscus cells and bone marrow mesenchymal stromal cells. BMC Musculoskelet Disord. 2013 Jul 22;14:216.doi: 10.1186-1471-2474-14-216.

Haddad B, Haddad B, Konan S, Adesida A, Khan WS. A systematic review of tissue engineered meniscus re-placement strategies: preclinical models. Curr Stem Cell Res Ther. 2013 May;8(3):232-42. Review Haddad B, Pakravan AH, Konan S, Adesida A, Khan W. A systematic review of tissue engineered meniscus: cell-based preclinical models. Curr Stm Cell Res Ther. 2013 May;8(3):222-31. Review

Thangavelu G, Gill RG, Boon L, Ellestad KK, Anderson CC. Control of in vivo collateral damage generated by T cell immunity. J Immunol. 2013 Aug 15;191(4):1686-91. doi: 10.4049/jimmunol.1203240. Epub 2013 Jul 12. Mold JE, Anderson CC. A discussion of immune toler-ance and the layered immune system hypothesis. Chimerism. 2013 Jul-Sep;4(3):62-70. doi: 10.4161/

chim.24914. Epub 2013 May 3.

Al-Adra DP, Anderson CC. Toward minimal conditioning proto-cols for allogeneic chimerism in tolerance resistant recipients. Chimerism. 2013 Jan-Mar;4(1):23-5. doi: 10.4161/chim.23350. Epub 2013 Jan 1. Momtazi M, Kwan P, Ding J, Anderson CC, Honardoust D, Goekjian S, Tredget EE. A nude mouse model of hypertrophic scar shows morphologic and histologic characteristics of human hypertrophic scar. Wound Repair Regen. 2013 Jan-Feb;21(1):77-87. doi: 10.1111/j.1524-475X.2012.00856.x. Epub 2012 Nov 5.

Asai-Coakwell M, March L, Dai XH, Duval M, Lopez I, French

CR, Famulski J, De Baere E, Francis PJ, Sunaresan P, Sauvé Y, Koenekoop RK, Berry FB, Allison WT, Waskiewicz AJ, Lehmann OJ. Contribution of growth differentiation factor 6-dependent cell survival to early-onset retinal dystrophies. Hum Mol Genet. 2013 Apr 1;22(7):1432-42. doi: 10.1093/hmg/dds560. Epub 2013 Jan 9.

Oltean M, Churchill TA. Organ-Specific Solutions and Strategies for the Intestinal Preservation. Int Rev Immunol. 2013 Dec 12. [Epub ahead of print] Salim SY, Young PY, Lukowski CM, Madsen KL, Sis B, Churchill TA, Khadaroo RG. VSL#3 probiotics provide protection against acute intestinal ischemia/reperfusion injury. Benef Microbes. 2013 Dec 1;4(4):357-65. doi: 10.3920/BM2013.0026.

Kawahara T, Toso C, Yamaguchi K, Cader S, Douglas DN, Nour-bkhsh M, Lewis JT, Churchill TA, Yagita H, Kneteman NM. Addi-tive effect of sirolimus and anti-death receptor 5 agonistic antibody against hepatocellular carcinoma. Liver Int. 2013 Oct;33(9):1441-8. doi: 10.1111/liv.12275. Epub 2013 Jul 29.

Tso VK, Sydora BC, Foshaug RR, Churchill TA, Doyle J, Slupsky CM, Fedorak RN. Metabolomic profiles are gender, disease and time specific in the interleukin-10 gene-deficient mouse model of inflammatory bowel disease. PLoS One. 2013 Jul 9;8(7):e67654. doi: 10.1371/journal.pone.0067654. Print 2013.

Kawahara T, Lisboa FL, Cader S, Douglas DN, Nourbakhsh M, Pu CH, Lewis JT, Churchill TA, Humar A, Kneteman NM. Human Cytomegalovirus infection in humanized liver chimeric mice. Hepatol Res. 2013 Jun;43(6):679-84. doi: 10.1111/j.1872-034X.2012.01116.x. Epub 2013 Feb 26.

Mital P, Kaur G, Bowlin B, Paniagua NJ, Korbutt GS, Dufour JM. Nondividing, Post-Pubertal Rat Sertoli Cells Resumed Prolifera-tion after Transplantation. Biol Reprod. 2013 Nov 27. [Epub ahead of print]

Ellis CE, Suuronen E, Yeung T, Seeberger K, Korbutt GS. Bioen-gineering a highly vascularized matrix for the ectopic transplanta-tion of islets. Islets. 2013 Nov 21;5(5). [Epub ahead of print]

Vulesevic B, McNeill B, Geoffrion M, Kuraitis D, McBane JE, Loch-head M, Vanderhyeden BC, Korbutt GS, Milne RW, Suuronen EJ. Glyoxalase-1 overexpression in bone marrow cells reverses de-fective neovascularization in STZ-induced diabetic mice. Cardio-vasc Res. 2013 Dec 16. [Epub ahead of print] McBane JE, Vulesevic B, Padavan DT, McEwan KA, Korbutt GS, Suuronen EJ. Evaluation of a collagen-chitosan hydrogel for po-tential use as a pro-angiogenic site for islet transplantation. PLoS One. 2013 Oct 18;8(10):e77538. doi: 10.1371/journal.pone.0077538.

McEwan K, Padavan DT, Ellis C, McBane JE, Vulesevic B, Kor-butt GS, Suuronen EJ. Collagen-chitosanlaminin hydrogels for the delivery of insulin-producing tissue. J Tissue Eng Regen Med. 2013 Oct 30. doi: 10.1002/term.1829. [Epub ahead of print]

Jeyakanthan M, Zhou X, Tao K, Mengel M, Rajotte RV, Larsen I, West LJ. Failure of neonatal B-cell tolerance induction by the ABO-incompatible kidney grafts in piglets. Transplantation. 2013 Sep;96(6):519-28. doi: 10.1097/TP.0b013e31829b0840.

22

The Division of Thoracic Surgery saw a transition in leadership over the latter half of 2013 with Dr. Eric Bédard accepting the position of division director following Dr. Ken Stewart stepping down earlier in the year. The division hosted Grand Rounds in October 2013 where Dr. Sean Grondin (Calgary) present-ed his work on workforce planning for thoracic surgeons in Canada. Teaching remains a priority for the division and, despite its small size, continually contributes to the education of both students and residents with all members participating the Discovery Learn-ing, Gilbert Scholar programs, and / or didactic teaching in addition to RCPSC Examination Committee. Three division members have been awarded awards for excellence in teaching at the undergraduate level. Dr. Bédard leads clinical and translational research with expanding collaborations with the Cross Cancer Institute. The main focus is on the early diagnosis of lung cancer via a novel sputum based microRNA test developed in Alberta. This collaboration has led to presenta-tions at both National and International meetings. Over the coming year thoracic surgery will be moving to synoptic OR reporting in collaboration with Cancer Surgery Alberta and will also to de-velop a platform for synoptic discharge summar-ies incorporating validated reporting of proce-dure related morbidity for QA/QI endeavors. The-se will function as building blocks for a more seamless and robust clinical research and outcome platform and the Section will need to develop both personnel and IT resources in order to support this new direction.

Awards

Dr. Azim Valji, Top Ten Surgical Subspecialty Teacher Award. Dr. Ken Stewart, Top Ten Surgical Subspecialty Teacher Award. Dr. Eric Bédard, Discovery Learning Preceptor Excellence Award.

Grants

E. Bédard and R. Razzak. ―The evaluation of Micro-RNA expression profiles in Sputum, Sera and Urine for the early detection of Non-Small Cell Lung Cancer‖. Edmonton Civic Employees Research Award, $9950.

Publications

Manuscripts: 3 (all peer reviewed) Published abstracts: 7 (all peer reviewed) Scientific Presentations (International peer re-viewed meetings): 5 Scientific Presentations (National peer reviewed meetings): 3

Thoracic

Surgery

Divisional Director: Dr. Eric Bédard

The Division of Urology is committed to the improvement of health through excellence in patient care, leadership in education and research, and in preventative initiatives directed at the promotion of increased urological well being. All members of the division are faculty members and take the initiative to interact and educate residents, medical students and elective students.

Distinguished Visitors

February 3, 2013 - February 16, 2013

Dr. Toshiaki Tanaka, Professor of Urology,

Sapporo University.

May 17, 2013 Dr. Wayne Hellstrom, Professor of Urology, Chief of Andrology, Tulane University School of Medicine, New Orleans, LA ―Reconstructive Surgery for Peyronie‘s Disease: Tricks of the Trade.‖ October 4, 2013 Dr. Wes Kassouf Director, McGill Urology Training Program, Assistant Professor, Department of Surgery (Urology), McGill University ―Overcoming radioresistance in bladder cancer through molecular signalling.‖ November 15, 2013 Dr. Kishore Visvanthan Clinical Professor of Surgery, University of Saskatchewan, Saskatoon Health Region ―Turn Frustration into Satisfaction: Quality Improvement in a Community Urology Practice.‖

Appointments

July 1, 2013 Dr. Niels Jacobsen, Associate Professor.

August 1, 2013 Dr. Adrian Fairey, Assistant Professor. March 1, 2013 Dr. Howard Evans, Appointed Urology Site Chief Misericordia Hospital. March 1, 2013 Dr. Gary Gray, Appointed Site Chief Misericordia Hospital.

Awards

Frank Squires Scholarship in Urology Dr. Phil Bach Dr. Conrad Maciejewski Top Ten Teacher Award Dr. Tim Wollin Dr. Keith Rourke

Top Ten Teacher Award UMG Dr. Blair St Martin

Urology Resident Teaching Award Dr. Howard Evans

Division of Urology Resident Research Day 1

st Place Research Paper – Dr. Joe LaBossiere

2nd

Place Research Paper – Dr. Adam Kinnaird 2

nd Place Research Paper – Dr. Jeffrey Zorn

The E. William Kuder Memorial Prize in Surgery Dr. Nathan Hoy Second Prize, Best Member Presentation Award, Northwest Urology Society Dr. Keith Rourke

Grants

$35,000 to Dr. Niels Jacobsen for Correlation of Bladder Cancer Tissue Microarray Analysis with Clinical Outcomes.

23

Urology

Divisional Director: Dr. Gerry Todd

Program Director: Dr. Niels Erik Jaconbsen

$150,000 to Dr. Ron Moore for Development of Novel Oncolytic Poxviruses. $510,595 to Dr. Ron Moore for Real-time Functional Optical Resolution Photoacoustic Microscopy and Micro-Endoscopy for Cancer. $200,000 to Dr. Ron Moore for PDT of Prostate Cancer. $750,000 to Dr. Ron Moore for Development of safer oncolytic poxviruses dependent on cellular dNTP synthesis. $750,000 to Dr. Ron Moore for Non-invasive Staging of Prostate Cancer: Translating Biomarkers to Clinical Practice. $5,000 to Dr. Keith Rourke for Quality of Life and Clinical Outcomes after Urethral Reconstruction. $24,000 to Dr. Keith Rourke for Quality of life and outcomes assessment after urethral reconstruc-tion. $5,000.00 to Dr. Darcie Kiddoo for An RCT of Hydrophilic vs Non-hydrophilic PVC Catheter use in Spina Bifida.

$9,566 to Dr. Peter Metcalfe for Use of Mesenchymal Stem Cells in the Prevention and Treatment of Bladder Fibrosis. $10,000 to Dr. Peter Metcalfe for Recruitment and Assessment of Mesenchymal Stem Cells in an Animal Model of Partial Bladder Outlet Obstruction. $3,000 to Dr. Peter Metcalfe for Retrospective Review of Children with Renal Stones. $3,000 to Dr. Peter Metcalfe for Indications for UPJ repair in Children. $3,000 to Dr. Peter Metcalfe for A Modification of the TIP Procedure for Distal Hypospadias – the Burrowing Technique.

Totals $2,458,161

Publications

Book Chapters – 2 Abstracts – 21 Journals – 31 Med Ed Portal Sessions – 5 Internet Publications – 1

24

25

Our undergraduate program remains one of the strongest and most innovative in the country, and faculty continues to excel in undergraduate teaching. The Class MD 2013 scored above the national average in the surgery component of the MCCQE Part 1 and thirty of the graduating class of 2013 took up positions in surgical residency training, (a rate of approximately 1 in 6). We have now established the Summer Studentship Program in Surgical Education; in 2013, there were 7 summer students conduct-ing various projects in the field of surgical education. Program evaluation and student achievement data continue to show sustained high performance by our faculty and students. We continue to offer high-quality surgical teaching at 6 hospital sites across Edmonton and in St. Albert and Fort Saskatchewan. The undergrad-uate education team has continued to lead the way and innovate in the use of new teaching technologies. The clerkships switched to the new curriculum system MedSIS in September 2012, a year before implementation in other clerkships and have learned much about the strengths and weaknesses of the new system. The ‗Surgery 101‘ podcast series has continued to attract much attention worldwide. 2013 saw the series exceed 150 episodes and 1,000,000 downloads in over 170 countries. This year a new Surgery 101 app for the iPhone and a new Surgery 101 website was launched and a part-nership with the School of Business to explore the field of online marketing. The program of research in surgical education has continued to grow, with grant- funded

research projects, publications, presentations and an increasing number of graduate students pursu-ing advanced degrees in education. The UGME team presented 13 projects at the 2013 Canadian Conference in Medical Education and multiple members received teaching awards this year, for research enhancement (Shannon Erichsen), pre-clinical and clinical teaching (Drs. Allan Ho and Kamran Fathimani) and for innovation in education research (Dr. Jonathan White). The team also continued to renew itself this year, with the appointment of two new clerkship directors for our courses in undergraduate surgery. Dr. Allan Ho replaced Dr. Rob Chan as the director of the Year 4 course, while Dr. Heather Cox replaced Dr. Kam Fathimani as director of the Year 3 course.

Student Performance in 2012 2013 SURG 546 General

Surgery, Anesthesiology

& Pain Medicine

152 of 152 students of the

Class of 2014 in the

mandatory rotation SURG

546 were issued passing

grades in general surgery at the end of the 3rd

year of the MD Program in August 2013.

SURG 556 Speciality

Surgery 180 of 180 students of the

Class of 2013 in the

mandatory rotation SURG

556 were issued passing

Undergraduate Senior Director: Dr. Jonathan White

Medical Education

26

grades in Speciality Surgery at the end of the 4th

year of the MD program in May 2013. Data

shows that UGME was able to accommodate

―The Bubble‖ class with the same level of

experiences as previous classes with no issue.

The Class MD 2013 scored above the national

average in the Surgery component of the

MCCQE Part 1.

Faculty Performance in 2012 2013 UGME provided a total of 3302 learning encoun-ters for medical students in the academic year 2012-2013 (a ‗learning encounter‘ is defined as an educational experience taking place between a student and a teacher). 213 members were engaged in formal education of our undergradu-ate students, an increase from the previous year (165 members). Informal teaching was also pro-vided by the residents in various divisions. Program evaluation data for this year has shown continued improvement across all undergraduate rotations. The average number of learning encounters per teaching surgeon per year was 17. The median student rating of preceptors was 4.47 out of 5. Forty-nine members of the depart-ment provided a total of 313 teaching hours in mandatory clerkships with a median student rating of 4.40 out of 5 (these figures do not include sessions in the Gilbert Scholars program, the pre-clinical blocks and Discovery Learning). Teaching evaluation scores were issued to all department members in January 2014. This teaching evaluation data was used to

identify the Top 10 Teachers in the two under-

graduate courses, and these educators will be

honoured at the Department‘s annual Awards

Dinner in May 2014.

Senior Director: Dr. Jonathan White

Top 10 Teachers General Surgery 2012-2013

Dr. Ghassan Alhassani

Dr. Klaus Buttenschoen

Dr. Michael Chatenay Dr. Curtis Ciona

Dr. Kam Fathimani Dr. Ramesh Juta

Dr. Shahzeer Karmali Dr. James Stewart

Dr. Jonathan White

Dr. Walter Yakimets

Top 10 Teachers Specialty Surgery 2012-2013

Dr. Niels Jacobsen

Dr. Dan O’Connell

Dr. Keith Rourke

Dr. Blair St. Martin

Dr. Ken Stewart

Dr. Gerry Todd Dr. Jon Toy

Dr. Azim Valji

Dr. Tim Wollin

Dr. Erin Wright

27

Surgery continued to play a key role in discussions surrounding the resident duty hour issue. Dr. Erin Wright spearheaded Faculty-wide discussion pertaining to the resident duty hours debate when he organized the second and third installments of the Resident Duty Hours Symposium on February 15, 2013 and June 5

th, 2013. Many program directors in sur-

gery began to implement modifications to their programs with regards to competency based medical education (CBME) and modifying their assessment practices. Staying on trend in surgical education,

programs saw a boom in the implementation of

―boot camps‖ for junior residents. The Surgical

Foundations program ran a boot camp through

the summer of 2013, introducing PGY-1

residents to the fundamentals of surgery. The

Neurosurgery specialty committee collaborated

on a 4-day national boot camp, while Orthopae-

dic surgery organized several hands-on events,

incorporated into the resident‘s first 6 months.

2013 Events

Surgical Foundations

Dr. Erika Haase implemented a summer long boot-camp session on the Fundamentals of Surgery into the Surgical Foundations curricu-lum and introduced further START days (Surgery and Trauma Acute Resuscitation training) with Dr. Damian Paton-Gay. An open skills training - advanced wet lab session is being tailored after the pilot installment in 2012.

CanMEDS Dept-Wide Resident Seminars

Sessions are provided to the entire cohort of surgical residents each year. These sessions address different areas across the CanMEDS competencies.

5

th Annual CanMEDS OSCE: November 12,

2013 The annual PGY-2 Resident CanMEDS OSCE improves each year and continues to be an important part of the formative assessment of residents; providing them with an opportunity for self-awareness. Residents appreciate the immedi-ate feedback from staff after each scenario.

ICRE, Calgary 2013 In September, Calgary hosted this year‘s Royal College International Conference on Residency Education with the theme of ―Educational Outcomes: Inspiring Residents, Improving Care‖.

Postgraduate

Surgical Education

Senior Director: Dr. Erin Wright

CanMEDS Role Topic Preceptor

Date

Communicator /

Health Advocate

"Advanced Care Planning (ACP): Goals for Care Discussions"

Dr. Mike Meier

Jan 11, 2013

Communicator Simulation

―Communication in Crisis: Practical Communication and Crisis Management Skills in Acute Care Surgery‖

Dr. Cian O'Kelly & Dr. Peter Brindley

April 12, 2013

Manager

"Starting a Surgical Practice - Choices after Residency"

Dr. Yvonne Chan, University of Toronto

Sept

13,

2013

Once again, the Department of Surgery sup-ported attendance of three surgical program directors along with Dr. Hedden, chair and Diane Titley, assistant chair. As well, seven administrative staff from the Postgraduate Office of Surgical Education attended the administrator track meeting and conference with the support from the Department of Surgery, the Postgraduate Medical Education Office and the University of Alberta‘s Human Resources Development Fund (HRDF). This year, Neurosurgery residency program director, Dr Cian O‘Kelly was selected to present in the top five ―What Works‖ paper session on ―How to build a national boot-camp: Experience from the Canadian Neurosurgical rookie camp‖. Dr O‘Kelly was also accepted to present in the paper session on resident duty hours where he gave his innovative solutions to neurosurgery coverage at the Royal Alexandra Hospital with ―Home-call to address duty hours for neurosurgical residents: Impact on case-volume, qualitative education experience and resource requirements‖.

CaRMS 2013 During 2013 CaRMS approximately 184 candidates were interviewed for 19 residency opportunities in the Department of Surgery. The Department of Surgery was extremely suc-cessful in the recent CaRMS match and the programs are quite pleased with the results.

Staffing Changes-2013 There were 3 new Program Directors in 2013: Dr. Dan Schiller has completed a successful term as general surgery program director and Dr. Kamran Fathimani assumed the new role. Dr. Keith Rourke turned the role of urology program director over to Dr. Niels Jacobsen. Dr. Rod MacArthur has also completed a successful term as cardiac surgery program director and Dr. Shaohua Wang assumed the role.

Division Residents Fellows

Cardiac Surgery 5 9

General Surgery 48 7

Neurosurgery 8 5

Orthopaedic Surgery 21 3

Otolaryngology - Head & Neck Surgery

12 4

Plastic Surgery 15 2

Urology 11 2

Clinical Investigator Program (CIP)

7

Total residents 120 32

Off-service residents on rotation in surgery

338

We would like to thank the outgoing program directors for their commitment and outstanding service and look forward to working with this group of enthusiastic and energetic new PDs.

There were 2 New Program Administrators:

Hannah Hamilton, General Surgery Program Assistant.

Peggy Yin, Surgical Foundations Program Administrator.

Walk for ALS

The Office of Surgical Education spear-headed the organization of a team to participate in the ―Walk for ALS‖ on June 8, 2013, in Hawrelak park. Walking in honour of Dr. Drew Sutherland, the team included Department of Surgery members, their family and friends. Team ―Drew‘s Crew‖ consisted of 40+ walkers and raised $32,000 for the ALS community.

PGME Residents Numbers 2012-2013 year

28

29

We have been fortunate to maintain a steady enrolment in the Department of Surgery Graduate Program. Approximately half of the master of science students are residents funded through the Clinical Investigator Program (CIP). The program has a number of doctor of philosophy (PhD) students who are residents receiving CIP funding for two years of their program. Funding for the remainder of their program and for all basic science students is dependent on grants, scholarships, awards and/or supervisor support.

Presentations Students presented 11 oral abstracts and 3 posters at local conferences. Nationally 3 oral abstracts and 3 posters were presented in addition to 2 oral abstracts and 3 posters presented at international conferences.

Awards In 2013 graduate students were awarded $94,250 in grants and awards. $36,000 of the total award dollars were from funding agencies outside the University of Alberta. 5 students won awards for either basic or clinical science in both oral and poster presentations at the 2013 Tom Williams Surgical Research Day. Students receiving awards in 2013 include: Ali Alsagheir Bader Alsaikhan Rositsa Bogdanova Roger Croutze Boris Gala Lopez Mohammed Jomah

Mahra Nourbakhsh Troy Perry Caroline Sheppard Joshua Wong Pang Young Hana Yu

Publications Graduate students have successfully submitted articles for publication. 2013 saw 7 publications with program students as first author. An additional 2 abstracts with program students as co-author were also published.

Graduate Students Change of Category One resident changed from the master of science program to the doctor of philosophy program this year. Dr. Troy Perry made the change effective Jan-uary 1, 2013.

Students Successfully completed Candidacy

Exam Shakti Singh – June 26, 2013 Rotem Lavy – November 22, 2013 Troy Perry – December 9, 2013 Rene Razzak – December 16, 2013 Pang Young – December 18, 2013

Students Successfully defended MSc Degree David Chapman ―Utilizing Positron Emission Tomography to Detect Functional Changes Following Drug Therapy in a Renal Cell Carcinoma Mouse Model‖ (January 20,

Graduate

Program

Senior Director: Dr. Tom Churchill

2013) [Supervisor: Dr. Ronald Moore]. Roger Croutze ―Structural and molecular characterization of the human meniscus for application in tissue engi-neering‖ (March 29, 2013) [Supervisor: Dr. Nadr Jomha and Adetola Adesida]. Jean-Sebastien Pelletier ―Vasopressin and the Asphyxiated Neonate‖ (May 24, 2013) [Supervisor: Drs. David Bigam and Po-Yin Cheung]. Joseph LaBossiere ―The use of Doxycycline in Asphyxiated New-borns‖ (May 29, 2013) [Supervisor: Drs. David Bigam and Po-Yin Cheung]. Joshua Wong ―Sensory Nerve Injuries: Advances in Diagnosis and Novel Therapy to Enhance Sensory Recov-ery in Humans‖ (June 4, 2013) [Supervisor: Drs. Jaret Olson and Ming Chan]. Bader Alsaikhan ―The Proteome of Partial Baldder Outlet Obstruc-tion and the Therapeutic Role of Mesenchymal Stem Cells‖ (June 27, 2013) [Supervisors: Dr. Peter Metcalfe]. Chart: Students Registered in Experimental

Surgery

Sonia Cader ―TWEAK-Fn14― (December 5, 2013) [Supervisor: Dr. Norman Kneteman]. Hana Yu ―Enhancing Chondrogenesis of mesenchymal stromal cells through anti-Thy1 strate-gies‖ (December 10, 2013) [Supervisor: Dr. Nadr Jomha and Adetola Adesida].

Students Successfully defended PhD Degree Mahra Nourbakhsh ―Role of TG Lipases; Arylacetamide Deacetylase and Triacylglycerol Hydrolase in Hepatitis C Life Cycle‖ (March 22, 2013) [Supervisor: Dr. Norman Kneteman] Mathew Varkey ―Development of Novel Non-Scarring Tissue Engineered Skin to Treat Burn Patients and others with extensive skin loss‖ (April 2, 2013) [Supervisor: Dr E. (Ted) Tredget] Subodh Samrat ―Modulation of Immune Response by HCV-derived F, Core and NS3 Proteins‖ (September 9, 2013) [Dr. Babita Agrawal]

Domestic Basic Science MSc

Int‘l Basic Science MSc

Resident MSc

Total MSc

Domestic Basic Science PhD

Int‘l Basic Science PhD

Resident PhD

Total PhD

Total Student Enrolment

Winter 2013

5 8 7 20 6 7 4 17 37

Fall 2013

8 9 5 22 3 6 4 13 35

30

Senior Director: Dr. Tom Churchill