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PHYSICAL PLANT N o -2 7 1 2 P - I

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'DcpL otErniironmcntal HeWIi i£ Safety: 233 Willisan Suva1 Highrisc

Middletown. CT 06459

28April05

To: Thomas ThompsonNRC Licensing division

K - Mail Control # 136061

From: WS Nelligan

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Re; Requested Comments for Materials License Renewal

4, Mr. Thompson: -

- Please find attached our response to statements found in NUREG-1556, Vol 7, followed bymaps of our facility, for a total of 12 pages. (13 including this cover page)

If you have questions please feel free to call me at (860)685-2771 or Donald Albert at(860)685-2729, 1 look forward to your response.

- Regards,

Ur� �q �4.

IL'> -

William S. Ne}Iigan 'Associate Director

, . Environmental Health & Safety,-"O i yJ

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J::~sI~t~ MATERIALS.O'G2

APr,.28. 2005 2:18PM

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Dept ofEnvironr

PHYSICAL PLANT

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No 2712 P. 2

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entail Health & SatretY233 William Strcet HighrlseMiddletown. CT 06459

NRC License Renewal ApplicationApril 2005

.

rial e ss s edAct - . temi 1- 8.5.1 Radioactive Alatena to be Possesse

Element & ChemicalMass andlor Physical Maximum Proposed Use

- ~AmountNumber Form

,i-ydrooen 3 Bound/Non-Volatile 500 millicuries ADP/ATPIASE study. Thyrnadine injection intofinches to follow brain development.

Carbon 14 Any 12 millicuries Methylated markerPhosphorous 32 Any 30 millicuries DNA/protein labelingPhosphorous 33 Any 30 millicuries DNA/protein labelingSulfur 35 Any 30 millicuries Nucleotide labeling. DNA/Protein labelingCalcium 45 Any I millicurie Research and development as defined in;_ lOCFR30.4

I: iron 59 Any 5 millicuries Research and development as defined inIOCFR30.4

Iodine 125 Bound/Non-Volatile S millicuries Protein labeling, biochemical study

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Understanding:

Radioactive material possessed under the terms of one or more license exemption or under the terms ofone or more general license will not impact the quantity limits specified above, are not included whencalculating the sum of the ratios to meet the requirements of I OCFR30.35(d), 10CFR40.36(b), orI OCFR70.25(d), and will not be included in the required semi-annual inventory of licensed material.Examples of such exemptions and general licenses are listed below.

10CFR30.1410CFR30.1 8IOCFR31I OCFR40.13I OCFR40.221OCFR70.19

Exempt ConcentrationsExempt Quantities.General Domestic Licenses for Byproduct MaterialUnimportant Quantities of Source MaterialSmall Quantities of Source MaterialGeneral License for Calibration or Reference Sources

Possession of naturally occurring radioactive material (NORM) and accelerator-produced radioactivematerial (NARM) is not regulated by NRC.

Pagc I of 6L -t

Wesleyan UVzverii~NRCLIome Renewal Appgcadon

April 2005

Apr.28. 200' 2:18PM PHYSICAL PLANT ' No-2712 P. 3

Item 2: 8.6 P . F h i d a l U

Item 2: 8.6 Purpose For.WVhich Licensed Maternal Will Be Used:

* . A., -T -Licensed material will be used for research and development as defined in I OCFR30.4 and as describedtt e -~ 3a~ 'r-i the above table. ,This research and development will include small animal studies.

-' - -_ Ifem 3: 8.7.1 Radiation Safety Officer

The proposed new radiation safety officer will be William S. Nelligan, Associate Director of- Environmental Health and Safety. His resume was submitted to the NRC in the original application for

renewal dated Nov 2004.

IteMn 4: 8.7.2 Authorized Users

J-. Licensed material will be used by or under the supervision of, the following Principle Investigators:. _: - be - = (rdsuaE's were previously submitted to the NRC)

_ , . Philip Bolton;- 2. Laura Grabel

3. Manju M. Hingorani7 4. Anthony Infante

5. John Kirn. 6. rDonald A. Oliver.

7. Rex Pratt8. rina Russu

. .. 9. Anne Baranger' ,,' , I O. Michael A. McAlear.&- .= g11.-Michael Weir a ,

-. 5'12. Scott Holmes13. Jason Wolfe

.Palease remove the following names from thI, William Firshein (retired.

e license:

..2. Janice Naegele (no longer doing research with radionuclides)

Item 5: 8.8 Training for Individuals Working in or Frequenting Restricted Areas

-- 4. Technical/Research Staff Training:7:4 i a>- .... ;*,R-'. During initial training, each trainee will be provided with sufficient information aboutmrdiation,

radioactivity, use of protective equipment and radiological work practices so that the staff member canwork in a safe manner, keep both their exposure and their co-workers' doses ALARA. Training will beaccomplished before any individual is permitted unescorted access to the restricted area.

The initial training program for all technical staffwill have a minimum duration of four hours, and willcover worker rights and responsibilities as well as all of the topics listed below:

Page

I. Principles and practices of radiation protection2. Radioactivity measurements3. Monitoring techniques for radiation and contamination4. The use of radiation and contamination monitoring instruments5. Mathematics6. Calculations basic to the use and measurement of radioactivity

2 or6 Wesleyan UniversiyN.RC Ucrne RenewdApplicadon

AprU2005

Apr.28. 2005 2 :,1 SP 1 PHYSICAL PLANT- N a -2 7 1 2 F - 4

-'- 9 ;s' 4 e '''if D

... 7. Biological effects of ionizing radiation8. Principles of the installation and removal of source holders or detector cells

^ ---- 9. 'Worker Rights and Responsibilities (IOCFR19)!-10. All the information provided in IOCFR19.12

-1. Wesleyan's byproduct material license and procedures12. Applicable and appropriate portions of IOCFR20, 30, 40 and 7113. Open Forum-Questions and Answers

During the initial training the trainee will be required to demonstrate to the RSO or designee the abilityt .:to properly perform a self-frisk.

t aAfter initial training each trainee will be required to pass a written examination covering the topicscontained in the training program. Minimum passing grade is 80%

Retraining will be performed annually., Retraining will be of at least one hour duration and will coversome portions of the material covered during initial training, plus items such as review of incidents,laboratory and calibration procedures and viewing of the Wesleyan Radiation Safety video and theHoward Hughes Safety video.

Ancillary Staff Training -

Each individual in these job categories who will have unescorted access to the restricted area will beprovided with sufficient information about radiation and radioactivity so that they can perform assigned

- .tancillazy duties in a safe manner.. a;,;

Training will be accomplished before any individual is permitted unescorted access to the restrictedarea.

rSThe training program for all administrativelsecretariaYjanitorial staff will have a minimum duration of30 minutes, and cover all of the topics listed below-.

I

1. Radiation and Radioactivity , .-a. Where they come fromb. Types of Radiation

2. Recognition of the radiation warning symbol3. Biological Effects of Radiation>4. Requirements of the license and the federal regulations regarding control of radioactive

materials and exposure to ionizing radiationS. Specific duties inside the restricted area

a. How to recognize incoming samplesb. Where to put incoming samplesc. Clear instructions about what to do and what not to do

6. What to do in case of a perceived emergency with regard to material or equipment inside therestricted area

7. Worker rights and responsibilities, including all the information provided in I OCFRI9.12 with- emphasis on NRC Form 3 and its application

8. Applicable and appropriate portions of lOCFR20, 30,40 and 71#_ ;, I` .-ItIr,.f. , - .. 41-0, 1:1'11�1 - ;�

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Each trainee will be required to pass a written examination covering the topics contained in the trainprogram. Minimum passing grade is 80%.

Retraining will be performed annually; the duration of retraining will be approximately 15 minutes.

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Pug 3of 6 ow 7akn nvtn~hyNRCL~ceise Rtnrwu1App~caeom

April2005

Apr.28. 2005 2:18PM

, . -

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PHYSICAL PLANT No.-27 12 P.- 5

Training and retraining will be accomplished by the RSO, a Principle Investigator or a similarlyqualified individual appointed by the RSO. Training documents will be maintained by the RSO.

m , pIteat 6:8.9 Facilities and Equipment

*:Licensed material will be used and stored at Wesleyan University, Hall-Atwater Laboratories andShanklin Laboratory, Lawn Avenue, Middletown, Connecticut. Floor plans of the specific roomsutilized, including the waste storage area, are contained in Appendix A of this document.

1 _. --

Item 7: Radiation Monitoring Instruments

Survey Meters

We will use instruments that meet the radiation monitoring instrument specifications published inAppendix M to NUREG-1556, Vol 7, "Program-Specific Guidance About Academic, Research and

- .-Development and Other Liceises of Limited Scope", dated December 1999. Additionally, we will.implement the model survey meter calibration program published in Appendix M to NUREG-1 556,

Vol. 7. "Program-Specific Guidance About Academic, Research and Development and Other Licensesof Limited Scope", dated December 1999,

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These instruments will be utilized to perform radiation and contamination surveys at WesleyanUniversity and will be calibrated every 12 m6nths, plus or minus one month. They will also becalibrated after any servicing of the instrument (other than a simple battery change or replacement of adetector cord with a cord of the same length). Calibrations will be performed by RSA Laboratories(license #06-30007-0 1) or by another company licensed to perform such services.

,The types and minimum numbers of survey meters that will be available at any one time are listed in-the table below. UWe reserve the right to upgrade our survey instruments as necessary.

Type Minimum #, . - Radiation Sensitivity Use. Available Detected Range

Portable thin-window G-M Survey and

pancak-e-type & 10 Beta-Gamma 0-600 kcpm monitoring, grossend window type testing of samples

survey meters ;

Portable G-M Survey andSide-wall detector .,Sre n

's -wath e te 1 . . Gamma 0.01-200 mR/h monitoring, grosswith exposure-rate testing of samples

meter -

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4 of 6 4of Jedlyan 11VenviryNRC Lkeive Nent 'sa!Applkciion

A~prl2005+ .71

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Tle Liquid Scintillation Analyzer listed in the table below will be used to perform quantitative analysison routine wipe tests. This instrument meets the radiation monitoring instrument specificationspublished in Appendix M to NUREG - 1556 Vol. 7 "Prograrn-Specific Guidance About Academic,Research and Development and Other Licenses of Limited Scope", dated December 1999.

a:: This Liquid Scintillation Analyzer listed below will be calibrated in place annually by a trained factory-'- representative. We reserve the right to upgrade our survey instruments as necessary.

The Portable Scintillation Counter listed below will be utilized to perform radiation and contamination. . . surveys of 1125 at Wesleyan University and will be calibrated every 12 months, plus or minus One

month. They will also be calibrated after any servicing of the instrument (other than a simple batterychange or replacement of a detector cord with a cord of the same length). Calibrations will beperformed by RSA Laboratories (license #06-30007-01) or by another company licensed to performsuch services.

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.w Available Radiation Detected Sensitivity UseLiquid <- -

Scintillation 1 Beta Io- UCi AnalyticalAnalyzer - m________nts

PortableScintillation 1 Gamma 12.6% efficiency Gamma detection

1125 on neck forcounterthoipanm

Item 8: 8.103 Material Receipt and Accountability

a .Vesleyan will maintain records of receipt, transfer and disposal of licensed material. The RSO or a-trained PI approves all orders for licensed material. -A written procedure for safely opening packages oflicensed material is in place; records of receipt, transfer and disposal of licensed material aremaintained. A physical inventory of licensed material will be conducted every six months plus or

;-minus I month. Licensed material will be stored and controlled in accordance with I OCFR20 Subpart I- Storage and Control of Licensed Material.Item 1 -Dose

~~- Item 9: 8.10.4 Occupational Dose

x ~ We have done a prospective evaluation and determined that unmonitored individuals are not likely toreceive, in one year, a radiation dose in excess of 10% of the allowable limits in 1OCFR20, or we will

~ .a - monitor individuals in accordance with the criteria in the section entitled 'Radiation Safety Program-'Occupational Dose' in NUREG 1556, Vol 7, "Consolidated Guidance about Materials Licenses:Program-Specific Guidance about Academic, Research and Development and Other Licenses ofLimited Scope" dated December 1999.

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WedI9WW UnivealfyNRC LICe we Renew..'alep~adion

April2005

A - .i: - pr.28. 2005 2 :ISP19P PHYSICNI PLANT 2 2':. No.9712 9P 7

Item 10: 8.10.6 Safe Use of Radionuclides and Emergency Procedures

Procedures for safe use, including security of materials and emergencies have been developed, and arecontained in the Wesleyan University 'Radiation Safety Plan for the Sciences", which is currentlybeing revised.-.Wesleyan University understands that these procedures may be revised only if 1) the

dchanges are reviewed and approved by the licensee management and the RSO in writing; 2) the licenseeA- staff is provided training in the revised procedures prior to implementation; 3) the changes are incompliance with the NRC regulations and the license; and 4) the changes do not degrade the

c peffectiveness of the program.

item 11: 810.7 Surveys

We will survey our facility and maintain contamination levels in accordance with the surveyfrequencies and contamination levels published in Appendix Q to NUREG-1556, Vol 7, "ConsolidatedGuidance about Materials Licenses: Program-Specific Guidance about Academic, Research and

L A-Development and Other Licenses of Limited Scope" dated December 1999."i� t - .

^ Item 12: 8.11 Waste Management

We will use the model waste procedures published in Appendix T to NUREG-1 556, Vol 7,"Consolidated Guidance about Materials Licenses: Program-Specific Guidance about Academic,

-. Research and Development and Other Licenses of Limited Scope" dated December 1999.

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