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Human Anatomy, 3rd editionPrentice Hall, © 2001
The Cardiovascular System
Chapter 13
Human Anatomy, 3rd editionPrentice Hall, © 2001
Introduction
• Cardiovascular system distributes blood– Pump (heart)– Distribution areas (capillaries)
• Heart has 4 compartments– 2 receive blood (atria)– 2 pump blood out (ventricles)– Vessels
• Veins return blood to the heart
• Arteries take blood away from the heart
Human Anatomy, 3rd editionPrentice Hall, © 2001
Superficial Anatomy of the Heart
• Atria = “entrance ways”– Thin-walled
– Upper chambers
• Ventricles = “hollow spaces”– Thick, muscular
• Apex points down & tips slightly to the left
• Base is superior – Great vessels attach
Human Anatomy, 3rd editionPrentice Hall, © 2001
The Coverings of the Heart
• Pericardium = “around the heart”– Visceral
pericardium = epicardium
– Parietal pericardium
– Pericardial space contains pericardial fluid
Human Anatomy, 3rd editionPrentice Hall, © 2001
Internal Anatomy of the Heart
• Chambers of the heart– Right & left atrium
• Separated by the interatrial septum
– Right & left ventricle
• Separated by the interventricular septum
Human Anatomy, 3rd editionPrentice Hall, © 2001
Structure of the Heart Wall
• Epicardium = “upon the heart” = visceral pericardium– Dense fibrous
connective tissue
• Myocardium is the middle layer– Cardiac muscle
• Endocardium = “inside the heart”– Simple squamous
epithelium
Human Anatomy, 3rd editionPrentice Hall, © 2001
The Great Vessels
• Superior & inferior vena cava– Return blood from
body to right atrium
• Coronary Sinus– Returns blood from
heart wall to right atrium
Human Anatomy, 3rd editionPrentice Hall, © 2001
The Great Vessels• Pulmonary veins
– Return blood (oxygenated) from lungs to left atrium
• Aorta– Takes blood from
left ventricle to body
• Pulmonary artery– Takes blood
(deoxygenated) from right ventricle to lungs
Human Anatomy, 3rd editionPrentice Hall, © 2001
Valves of the Heart• Atrioventricular (AV)
valves separate the atria from the ventricles– Tricuspid valve – right– Bicuspid valve (mitral)
– left • Semilunar valves
separate the ventricles from the great vessels– Pulmonary semilunar
valve– Aortic semilunar valve
• Heart sounds
Human Anatomy, 3rd editionPrentice Hall, © 2001
Valves of the Heart (Ventricular Diastole)
Human Anatomy, 3rd editionPrentice Hall, © 2001
Valves of the Heart (Ventricular Systole)
Human Anatomy, 3rd editionPrentice Hall, © 2001
Coronary Circulation
• Vessels that supply the myocardium itself– Right coronary artery– Left coronary artery – Cardiac veins
Human Anatomy, 3rd editionPrentice Hall, © 2001
Cast of Coronary Vessels
Human Anatomy, 3rd editionPrentice Hall, © 2001
The Cardiac Cycle• Contraction pattern
of the myocardium– Determined by the
conduction system– Systole =
contraction– Diastole = relaxation
• Both atria contract• Both ventricles
contract• Atria alternate with
ventricles
Human Anatomy, 3rd editionPrentice Hall, © 2001
Conduction System of the Heart• The average heart rate is 72 beats/min.• Depolarization stimulates contraction
Human Anatomy, 3rd editionPrentice Hall, © 2001
Conducting System of the Heart
• Depolarization begins in the sinoatrial (SA) node– Pacemaker
Conduction System of the Heart
•Depolarization spreads through atria, atria contract
Human Anatomy, 3rd editionPrentice Hall, © 2001
Conducting System of the Heart
• Atrioventricular (AV node) depolarizes
• Depolarization travels down the AV bundle (bundle of His)
Human Anatomy, 3rd editionPrentice Hall, © 2001
Conducting System of the Heart
• Depolarization spreads up the ventricular walls via Purkinje fibers.
– Ventricles contract
Human Anatomy, 3rd editionPrentice Hall, © 2001
Electrocardiogram
– ECG = a recording of electrical events in the heart• P wave = atrial depolarization• QRS wave = ventricular depolarization• T wave = ventricular repolarization
Human Anatomy, 3rd editionPrentice Hall, © 2001
Electrocardiogram
Human Anatomy, 3rd editionPrentice Hall, © 2001
Electrocardiogram
Human Anatomy, 3rd editionPrentice Hall, © 2001
Disorders
• Abnormal heart rates– Bradycardia– Tachycardia– Fibrillation
• Angina pectoris
• Myocardial infarction
Human Anatomy, 3rd editionPrentice Hall, © 2001
Blood Vessels
Human Anatomy, 3rd editionPrentice Hall, © 2001
Functions of Blood Vessels
• Carry blood away from the heart - arteries
• Transport blood to tissues - capillaries
• Return blood to the heart – veins
Human Anatomy, 3rd editionPrentice Hall, © 2001
Walls of Blood Vessels
• 3 layers– Inner layer is endothelium = tunica intima
• Simple squamous epithelium
– Middle layer = tunica media• Smooth muscle
– Outer layer = tunica externa• Dense fibrous connective tissue
Human Anatomy, 3rd editionPrentice Hall, © 2001
Atherosclerosis
Human Anatomy, 3rd editionPrentice Hall, © 2001
Arteries
• Elastic arteries– Large
• Muscular arteries– Medium-sized
• Arterioles– Very small– Capable of
vasoconstriction and vasodilation
Human Anatomy, 3rd editionPrentice Hall, © 2001
Systemic Arterial System
Human Anatomy, 3rd editionPrentice Hall, © 2001
Major Arteries of the Trunk
Human Anatomy, 3rd editionPrentice Hall, © 2001
Arteries of the Chest and Upper Extremity
Human Anatomy, 3rd editionPrentice Hall, © 2001
Capillaries
• All blood-tissue exchange occurs here
• Tissue = tunica intima only
Human Anatomy, 3rd editionPrentice Hall, © 2001
Capillary Bed with Precapillary Sphincters
Human Anatomy, 3rd editionPrentice Hall, © 2001
Veins• Venules
– Very small – Contain only tunica intima
and tunica externa
• Medium-sized veins and large veins– Contain same 3 layers as
arteries– Tunica media thinner – Tuna externa - thickest
layer
Human Anatomy, 3rd editionPrentice Hall, © 2001
Veins with Valves• Some veins contain valves – prevent blood
from flowing backwards
Human Anatomy, 3rd editionPrentice Hall, © 2001
Varicose Veins
• www.sirweb.org/patPub/varicoseVeinMain.shtml
www.veinhelp.com/varicoseVeins.htm
Human Anatomy, 3rd editionPrentice Hall, © 2001
Systemic Venous System
Human Anatomy, 3rd editionPrentice Hall, © 2001
Venous System of the Trunk and Upper Limb
Human Anatomy, 3rd editionPrentice Hall, © 2001
Blood Flow– Blood flows because of different pressures in the
system• Mean pressure in aorta = 100 mmHg
– Pressure decreases continuously through arterial and venous system• Arteries = 100 – 40 mmHg• Arterioles = 40 – 25 mmHg• Capillaries = 25 – 12 mmHg• Venules = 12 – 8 mmHg• Veins = 8 – 5 mmHg• Vena cava = 2 mmHg
Human Anatomy, 3rd editionPrentice Hall, © 2001
Blood Pressure– Definition – force exerted by blood on the wall
of any blood vessel– Clinical use – refers to pressure in the arteries
• Ventricles contract (systole)– Arterial pressure rises – Systolic pressure
• Ventricles relax (diastole)– Arterial pressure drops– Diastolic pressure
• Average blood pressure– 120/80 (young male)– 110/70 (young female)
– Hypertension