Http://genex-umb.sourceforge.net GenExplorer Team Members Prasoon Kejriwal Sumana Adma Ziping Zhu Chitra Karki Project AdvisorClient Prof. Ethan BolkerProf

http://genex-umb.sourceforge.net

GenExplorerTeam Members

Prasoon Kejriwal

Sumana Adma

Ziping Zhu

Chitra Karki

Project Advisor Client

Prof. Ethan Bolker Prof. Brian White


About GenExplorerAbout GenExplorer Idea behind the project

Develop an education tool for beginning biology students

Simulation of “Central Dogma” of Molecular Biology

Why GenExplorer? Why do we think it’s a good project ?

Huge market for such an application in the education industry

Very long lifespan of the software product

Capable Team Members

About our client


Central DogmaCentral Dogma DNA Sequence

5'-AAGGCTATAACCGAGATTGATGCCTTCTTAAGAAGGTGTGAGGGGGC- 3'

3'-TTCCGATATTGGCTCTAACTACGGAAGAATTCTTCCACACTCCCCCGG- 5'

Pre-mRNA Sequence (Transcription)

5'-CCGAGAUUGAUGCCUUGAGUAGGACCUUAAGAAGGUGUGA- 3‘

mRNA Sequence (Splicing)

5'-CCGAGAUUGAUGCCUUUUUAAGAAGGUGUGAAAAAAAAAAAAAA-3'

Protein (Translation)

N-MetProLeuSerArgGlyPro-C


Are we re-inventing the wheel?Are we re-inventing the wheel?

Issues with current applications on the webDoes not allow user interactionAre not user friendly

Where do we come in?Understand the end user as closely as possibleHave a clear knowledge about the requirementMake an extremely user-friendly and flexible application


Market ProspectsMarket ProspectsBusiness Objective

Developing and providing courseware for both classroom and web-based education.

Target MarketK9-12, college students, or any other learners and educators in biology related

fields. Market Size and Opportunity

Schools where bioscience is taught Students Fast Growing Potential of Stock Market In Instructional Technology

Competitors There are about 351 companies doing educational software business.

Higher EdApollo Group (Phoenix University?)Career EducationConcorde Career CollegesCorinthian collegesDeVryEducation ManagementITT Educ. ServicesStrayer EducationUniversity of Phoenix online


Increasing Biodiversity Education MarketIncreasing Biodiversity Education Market

High school, Grade 9-12

16,380,951

College, undergraduate

14,375,764

Percent of public high school graduates taking selected Biology course is 91.2%

Earned degrees in various fields of biology conferred by degree-granting institutions in 2000-01: 42,252

(2000. US Census)http://nces.ed.gov/pubs2003/digest02/tables/dt141.asp

Growth of youth in last 10 years


Fast Growing Fast Growing Potential of Stock Market In Potential of Stock Market In Instructional TechnologyInstructional Technology

86.5%

13.5%

63.2%

36.3%

InstructionalHardware

InstructionalSoftware

Centralized Decentralized

-90%

-60%

-30%

0%

30%

60%

K9-12 -40.0 6.5% 20.8%

Higher Ed 22.4% 25.7% 45.4%

CorporateLearning

-61.0%

18.6% 48.9%

KnowledgeInfrastructure

-55.0%

10.6% 30.1%

KnowledgeSolutions

-5.9% 5.4% 14.7%

Sept. 2002

May 2003

J uly 2003

2.12.5

2.8

3.64.3

4.85.4

6.7

8.36

5.6

7.85

4.7

6.95

4.2

6.45

3.53

5.74

3.55

5.80*

0

2

4

6

8

10

91

-92

92

-93

93

-94

94

-95

95

-96

96

-97

97

-98

98

-99

99

-00

00

-01

01

-02

02

-03

03

-04

*

E-rate

District Spending

* Projected

Source: ThinkEquity Partners Knowledge Notes Newsletter Median YTD Price: Aug. 18, 2003 and July 7, 2003 compared to May 19, 2003 and Sept. 16, 2002

Source: QED Ninth Annual Technology Purchasing Forecast, 2003-2004 Preliminary Data

Instructional Technology

Expenditures in U.S. School Districts13-Year Trend Expenditures

(Billions)


TeamTeamIndividual Strong Points of Team Members

Prasoon Kejriwal Strong background knowledge Industrial experience in biotechnology

Ziping ZhuReal world experience in educational researchVery good knowledge of User Interface Design

Sumana AdmaGood knowledge of design principlesVery good knowledge of User Interface Design

Chitra KarkiVery good knowledge of User Interface DesignTaken the introductory Biol 111 and Biol 112 courses with the client


Project ManagementProject ManagementManagement Strategy

Have a detailed plan in the beginning and make sure each team member abides with itStrictly follow schedules and meet milestones.Maintain to-do listsCommunicate with the client on a regular basisFreeze requirements at an earlier stage in order to minimize risk of schedule slippage and late delivery.Compromise on scope in order to deliver a good quality product.


Project ManagementProject ManagementDesign Strategy

Spend lot of time on the system architecture design User centered design Simplicity and continuous refactoring

Development Strategy Pair programming Small releases Continuous integration

Testing Strategy Write tests ahead of coding Run tests before every small release

Risk Strategy Identifying Analyzing Planning Monitoring


MILESTONES

Scheduled Date Milestones Description

Oct 14, 03 Vision Statement Final Vision Statement signed by the customer

Oct 30, 03 Project presentationPresentation of the

project to the prospective venture capitalists

Dec 4, 03Submit requirements

document

Hard copy of Requirements document to be submitted to Prof.

Bolker

Dec 20, 03"Hello world" application

running

Testing and coding of a small program to

understand the tool better

Jan 21, 04 Iteration 1 First bug free version

Feb 1, 04First formal application

checkpointDemo of the application to Prof. Bolker and the client

Mar 11, 04Formal Alpha release demo

with documentation

Demo of the Alpha release of application to Prof. Bolker and the client

Apr 20, 04Formal Beta release demo

with documentation

Demo of the Beta release of application to Prof. Bolker and the client

May 01, 04 Production release (1.0).Presentation to public (poster, demo) shortly

thereafter.

May 11, 04 Maintenance release (1.1) Maintenance release (1.1)


GenExplorer so far…GenExplorer so far…

Project Website establishedWebpage weekly updated

First version of use cases approved by clientA major milestone achieved so far

First draft of User Interfaces madeTo be discussed with the client in next meeting

Preliminary schedule established


Features of GenExplorerFeatures of GenExplorer

User FriendlyThis application is being developed keeping in view that it would be used by beginning biology students who could be naïve computer usersInvolve users in design of interfaces

Easily available

Web based – can use the application directly on web without downloading


Features of GenExplorer Features of GenExplorer cont..cont..

Main Features Highlighting

Editing

Transcription / Splicing / Translation

Folding ( ?? )

Modes of GenExplorer Instructor / Student / TA

Interactive / Non – Interactive

Strict / Relaxed


HighlightingHighlightingDNA Sequence

5'-AAGGCTATAACCGAGATTGATGCCTTCTTAAGAAGGTGTGAGGGGGC- 3' 3'-TTCCGATATTGGCTCTAACTACGGAAGAATTCTTCCACACTCCCCCGG- 5'

Pre-mRNA Sequence (Transcription)5'-CCGAGAUUGAUGCCUUGAGUAGGACCUUAAGAAGGUGUGA- 3‘

mRNA Sequence (Splicing)5'-CCGAGAUUGAUGCCUUUUUAAGAAGGUGUGAAAAAAAAAAAAAA-3'

Protein (Translation)N-MetProLeuSerArgGlyPro-C


ConclusionConclusion

• Why invest money in GenExplorer?– Very interesting and useful project– Capable team members– Doable in the time constraint– Would be definitely used by over 350 beginning

biology students at UMass, Boston every year.


http://genex-umb.sourceforge.netHAPPY HALLOWEEN !!HAPPY HALLOWEEN !!

Documents

Http://genex-umb.sourceforge.net GenExplorer Team Members Prasoon Kejriwal Sumana Adma Ziping Zhu Chitra Karki Project AdvisorClient Prof. Ethan BolkerProf