Hormone Balance for Optimal Health

HORMONE BALANCETHE KEY TO A

SANE LIFE

Dr. Laura NevilleNaturopathic Physician

Portland, ORwww.doctorneville.com

Copyright 2016, Laura Neville ND, LLC


WHO IS DR. NEVILLE?

Challenging childhood Diagnosed with a chronic, life-threatening

autoimmune disease at age 7 Lifelong relationship with the medical system

and conventional doctors for better or worse


“IF I WERE IN CHARGE…”


WHO IS DR. NEVILLE? Guided to healthcare career by

personal experience Compassionate and

empathetic. I’ve been there! Undergraduate study at the

University of California, Davis Studied Massage Therapy at

California Healing Arts College Naturopathic Doctorate from

the National College of Natural Medicine, Portland, OR

Private Practice in SW Portland Staff Physician at Labrix

Clinical Services in Clackamas


DISCLAIMER Discussions in this presentation are for

general information purposes only. Please discuss all personal treatments with your physician.

This discussion is NOT to take the place of your doctor


TAKE HOME POINTS Do not be limited by

your health challenges Be proactive Don’t rely on doctors

to give you the answers

You know your body better than anyone

Use health professionals as tools to help you along the way

No one can tell you that you won’t heal


WHAT ARE HORMONES?

Chemical Messengers: “Psssst” Created by Endocrine Glands Control most bodily functions from hunger

to metabolism, reproduction, emotions and moods

Many different types


THE KEY PLAYERS

Prostaglandins Adrenaline Aldosterone Calcitonin Cortisol Erythropoietin Glucagon Insulin Testosterone Leptin

Melatonin Oxytocin Estrogen Progesterone Prolactin Thyroxine Vitamin D


ENDOCRINE GLANDS


ALL ABOUT BALANCE When these hormones are in proper

balance, the body thrives

Even small fluctuations/imbalances can cause troublesome and even life-threatening effects.


SEX HORMONES

EstrogenProgesteroneTestosterone

All made from cholesterol!!


ADRENAL HORMONES

DHEA Cortiso

l


SYMPTOMS OF HORMONE IMBALANCE

REMEMBER THIS SLIDE!! COMMON, but not NORMAL

You are not crazy, it is not all in your head


MEN’S SYMPTOM CHECKLISTESTROGEN DOMINANCE

Decreased Urine FlowIncreased Urinary UrgeProstate Issues


MEN’S SYMPTOM CHECKLISTANDROGEN DEFICIENCYMETABOLIC SYNDROME

Weight Gain- Chest/Hips Weight Gain-Waist Decreased Libido Decreased Erections Ringing in the Ears High Cholesterol Elevated Triglycerides Hot Flashes Night Sweats Decreased Mental

Sharpness

Increased Forgetfulness Decreased Muscle Mass Decreased Flexibility Sore Muscles Increased Joint Pain Neck or Back Pain Bone Loss Rapid Aging Thinning Skin Decreased Stamina Burned Out Feeling Infertility Issues


OTHERWISE KNOWN AS… Mid-Life Crisis

Manopause Andropause

Viagra deficiency


TESTOSTERONE


FUEL TO THE FIRE Sedentary

lifestyle/little exercise

Poor diet Repetitive injury

(i.e. cycling) History of testicular

trauma Mumps

History of radiation Some genetic

conditions Medications Plastics Pesticides Excessive dietary

soy


THE VIAGRA EFFECT

Widespread use of Viagra has opened the lines of communication between men and their physicians

Discussion of ED treatment lay lead to larger discovery of underlying health concerns

ED patients are lucky. Huge link to metabolic syndrome/cardiovascular health

ED prompts men to seek treatment Treatment can SAVE LIVES


GRAVE CONSEQUENCES Low T can lead to:

Insulin resistanceDiabetesHigh blood pressureHeart DiseaseElevated TG and CholesterolDepression


METABOLIC SYNDROME Metabolic syndrome is a cluster of at

least three of five of the following medical conditions: abdominal (central) obesity elevated blood pressureelevated fasting plasma

glucose/elevated insulin levelshigh serum triglycerides low high-density lipoprotein (HDL) levels

Metabolic syndrome is associated with the risk of developing cardiovascular disease and diabetes.


LOW T + HIGH ESTROGEN Estradiol is a growth hormone and can

cause enlargement of prostate cells in men

Prostate hyperplasia “BPH” High estrogen causes SHBG to rise=

even less free (active) T available. Vicious Cycle!

AROMATIZATION Testosterone

Aromatase

Estradiol

**Fat cells are superb at this!!



SEX HORMONES: FREE VS. BOUND

Fat Loving Dissolve in oil and fat, but not in a

water-like environment such as blood Proteins (such as SHBG) are needed to

“carry” the hormones around in the blood

When “carried” they are bound to proteins and are inactive

3-5% of hormones are free/unbound 95-97% are bound/inactive and act as a

reservoir


T TO THE RESCUSE Raising T levels can stop the cycle

and treat metabolic syndrome Can turn insulin resistance around!

“Testosterone replacement therapy improves insulin resistance, glycemic control, visceral adiposity and hypercholesterolemia in hypogonadal men with type II diabetes”

Kappor D et al. Euro J Endocrin 2006;154: 899-906


PROSTATE CANCER Testosterone DOES NOT CAUSE prostate

cancerResearch out of Harvard over last several

years has shown that testosterone is not the cause of prostate cancer…but elevated estrogen may be!


YOUNGER MENHigh TLow EstradiolLow insulinLow incidence of disease


OLDER MEN Low T High Estradiol High insulin Higher incidence of disease


MEN’S SYMPTOM CHECKLISTADRENAL DYSFUNCTION

Stress Morning Fatigue Evening Fatigue Difficulty Sleeping Apathy Depression Foggy Thinking

Anxiety Irritability Nervousness Headaches Sugar Cravings Dizzy Spells Allergies


MEN’S SYMPTOM CHECKLISTTHYROID DISORDER

Cold Body Temperature Goiter Hoarseness Dry/Brittle Hair Brittle/Breaking Nails Constipation Slow Pulse Rate Rapid Heartbeat Heart Fluttering/Palpitations


WOMEN’S SYMPTOM CHECKLISTESTROGEN

DOMINANCE/PROGESTERONE DEFICIENCY

Irregular Periods Uterine Fibroids Water Retention Tender Breasts Fibrocystic Breasts Increased

Forgetfulness Foggy Thinking Tearfulness

Depression Mood Swings


ESTROGEN DOMINANCESUSAN (54 YEARS OLD)

“I have never had a weight problem, until now! I have always exercised regularly, eaten a pretty healthy diet, but now I’m gaining weight, especially around my middle…where is this belly coming from!?

“I have even been exercising more and eating less to stop the

gain. Nothing is helping. The pounds seem here to stay”


PROGESTERONEBALANCES ESTROGEN


HORMONE CYCLES


PROGESTERONE Produced by the ovaries. Surge in

second half of the cycle, after ovulation Small amount produced by the adrenal

glands Drug companies make a synthetic

hormone called progestin PROGESTINS ARE NOT PROGESTERONE

Different molecular structureThus vastly different effects in the bodyMany negative side effects


PROGESTERONE Promotes sleep Calming Reduces

cholesterol Helps estrogen Increases scalp

hair Burns fat for

energy Relieves

depression Diuretic

Reduces artery spasms

Maintains pregnancy

Balances estrogen effects on breast, brain, uterus

Promotes normal cell death

Helps body utilize glucose/improve insulin resistance

Helps thyroid gland


WOMEN’S SYMPTOM CHECKLISTLOW ESTROGEN

Hot Flashes Night Sweats Vaginal Dryness Incontinence

**Not as common as one would assume


LOW ESTROGENJANICE (49 YEARS OLD)

“I’m not myself anymore. I wake up 3-4 times per night, drenched in sweat. In the morning, I feel more tired than when I went to bed. At work, I have even had to leave a business meeting because I was so uncomfortable and embarrassed. You can actually see the hot flashes; my face turns beet red!”


MENOPAUSE Defined as cessation of menses for 12 consecutive

months Menopause is a gradual transition- may take up to 10

years to occur. Transitional period is termed peri-menopause Progesterone levels decline significantly Estrogen levels change as well, though rarely decline as

the same rate as progesterone Leads to an imbalance= estrogen dominance Risk factor for estrogen-dependent cancers,

osteoporosis, dementia and CVD DHEA, testosterone, and cortisol levels may also

fluctuate, compounding the symptoms picture Belly fat, scalp hair loss, weight gain, low libido, burn

out, rapid aging.


AFTER MENOPAUSE


WOMEN’S SYMPTOM CHECKLISTADRENAL DYSFUNCTION

Stress Morning Fatigue Evening Fatigue Difficulty Sleeping Decreased Stamina Anxiety Irritability Nervousness Ringing in Ears Fibromyalgia Allergies Headaches Sugar Cravings Dizzy Spells


ADRENAL DISORDER


ADRENAL DISORDER


ADRENAL DISORDER The cells in the body are constantly

breaking down and repairing. A large portion of the repair process

occurs during sleep Sleep deprivation/stress can age the

body very quickly. Repair is not taking place!


CORTISOL LEVELS Cortisol is a mediator of stress Regulates blood sugar Regulates electrolyte balance Regulates hormone balance Too much or too little is problematic


CORTISOL CURVE


ADRENAL FATIGUE



WOMEN’S SYMPTOM CHECKLISTTHYROID DISORDER

Cold Body Temperature Goiter Hoarseness Dry/Brittle Hair Brittle/Breaking Nails Constipation Slow Pulse Rate Rapid Heartbeat Heart Fluttering/Palpitations


WOMEN’S SYMPTOM CHECKLISTHIGH ANDROGEN/METABOLIC

SYNDROME Infertility problems Acne Increased Facial/Body Hair Scalp Hair Loss Weight Gain-Hips Weight Gain-Waist High Cholesterol Elevated Triglycerides


WOMEN’S SYMPTOM CHECKLISTLOW ANDROGENS

Decreased Libido Decreased Muscle Mass Thinning Skin Rapid Aging Aches and Pains Bone Loss


WOMEN AND TESTOSTERONE

Testosterone made in ovaries and adrenal glands

Women have 9 times less T than men Still very vital part of health Improves sleep Improves sense of well being and vitality Improves bone density Helps burn fat/slows fat build up


BREAST HEALTH

Estrogen and progesterone impact breast tissue Estrogen= cell growth and breast development Progesterone= balances the growth effect of

estrogen Imbalance= breast pain, cysts/lumps, fibrocystic

changes, tenderness, change in breast size


ESTROGEN E1= Estrone- 50-70% less active than E2. Made

mainly in fat cells. Highest after menopause E2= Estradiol- strongest. Made mainly in ovaries E3= Estriol- the most protective form of

estrogen. Only 10% as active as E2. Cannot be converted to E2 or E1

Dr. Henry Lemmon researched breast cancer patients and discovered that they had low levels of E3

EQ= E3/E1 + E2


SALIVA VS. SERUM Saliva testing= easy, measures

free/unbound portion of hormones. Represents the active hormone that is

available to tissues


DHEA Made in both ovaries and adrenal glands Important for libido and arousal Promotes sense of well being and

motivation Improves immune function Improves REM sleep Improves memory


WHY? High stress lives Much different pattern than in past days Adrenal glands and ovaries struggle to

produce the necessary hormones Estrogenic world Xenoestrogens Plastics- BPA (endocrine disruptors)


TEST THEN TREAT Sacred selfishness- take care of yourself first!

You cannot pour from an empty cup. Proactive action Make time for enjoyable activities Feed you body whole foods Deep belly breathing- 100 per day Exercise- at least 20 mins, 3 X per week Water Intake: ½ body weight in ounces per

day (unless kidney disease or congestive heart failure)

Optimize sleep! So important Laugh BHRT


TREATMENTS Fiber binds excess estrogen and removes it from

the body DIM- Brassica family: broccoli, brussel sprouts,

collards, kale, mustard greens, swiss chard Indole-3-Carbinol Vitex/Chaste Tree Berry Aromatase Inhibitors- Chrysin, Resveratrol, Zinc,

Luteolin Tribulus terrestris- Puncture Vine Eurycoma longifolia- Long Jack Epimedium- Horny Goat Weed Saw palmetto and Progesterone- blocks 5 alpha

reductase Stinging Nettles- binds SHBG, leave more free T


TREATMENTS FOR MENOPAUSE Stress management Avoidance of triggers: alcohol, caffeine, diet

pills, white sugar, spicy foods, hot food, hot tubs, saunas, hot showers, hot beds, hot rooms, hot weather, smoking

Exercise Diet Weight control Vitamin E, B, C Evening Primrose Oil Black Cohosh BHRT


ADRENAL TREATMENTS Stress management Exercise Sleep optimization Whole food diet Multivitamin/mineral Omega 3s Vitamin D Probiotics

Phosphorylated serine (for cortisol elevations)

Vitamin B5, B6, C, E Botanical

Adaptogens- Ashwaghana, Licorice, Rhodiola, Holy Basil

Adrenal glandulars Hydrocortisone


RESOURCES


RESOURCES


CONTACT INFO

Dr. Laura Neville1340 SW Bertha Blvd. Suite 200 Portland,

OR 97219503-244-0500

[email protected]

Documents

Hormone Balance for Optimal Health