DESIGNING FACILITIES FOR SCIENCE IN AN AGE OF FISCAL CRISIS

SCIENCE FACILITIES

a publication of

and their link to the financial crisisResearched and written by H. Michael Smith, AIA, LEED APSenior Vice President, National Science & Technology Leader, HKS, Inc.

In today’s tough economy, the business of

science has become extremely complex. The

reduction in funding; rapidly increasing global

competition for talent and resources; and the

need to create partnerships among government,

industry, and academic institutions are changing

the way scientists work. Now, more than ever,

the facilities in which they conduct their research

must be designed to attract new researchers

and also must be operationally efficient to

make the most of shrinking research budgets.

a publication of

Dallas County Southwestern Institute of Forensic Sciences, Dallas, Texas

IN AN AGE OF FISCAL CRISIS:

It is no surprise to our scientific research clients that industry and academia have undergone major financial belt-tightening due to the global economic crisis. Currently, in the United States, approximately 36 percent of research funding comes from the federal government, while the remaining 64 percent is derived from private industry, non-profit organizations, foundations and state funding sources. Facing a $16 trillion federal deficit if politicians cannot agree on how to improve the government’s fiscal outlook by January 2, 2013, pre-programmed, across-the-board

FUNDING SCIENTIFIC RESEARCH

a publication of

budget cuts of $1.2 trillion will go into effect.

In the worst-case scenario, these automatic cuts could mean that agencies such as the National Science Foundation and the National Institutes of Health would have to lower their grant acceptance rates. The impact also would be felt by the Centers for Disease Control and Prevention. The effect would be particularly disastrous for universities, which depend upon grants to help cover post-doctoral researchers and infrastructure costs. Grants to extramural investigators at

independent research institutes are likely to be hit particularly hard. States as well as non-profit organizations also will continue to experience dwindling endowments. And it will be worse two years from now as currently proposed cuts are loaded forward onto the 2014 fiscal year and beyond.

In the last century, more than half of our economic growth has come from investing in science and technology. By reducing our nation’s investment in scientific research, we risk losing our global competitiveness, national security,

health, standard of living, and economic growth. Therefore, it is critical for the United States to continue its investment in scientific research.

In the last century, more than half of our economic growth has come from investing in science and technology. By

reducing our nation’s investment in scientific research, we risk losing our global competitiveness, national security,

health, standard of living, and economic growth.

a publication of

In the last century, more than half of our economic growth has come from investing in science and technology. By

reducing our nation’s investment in scientific research, we risk losing our global competitiveness, national security,

health, standard of living, and economic growth.

H. Michael Smith, AIA, LEED APSenior Vice President, National Science & Technology Leader, HKS, Inc.

Concept for the Brain Performance Institute affiliated with the Center for BrainHealth, Dallas, Texas

CREATIVE WAYS TO SEEK

RESEARCH FUNDING

Alternative strategies and

sources of funding and cost-

effectiveness are available to

assist researchers in maintaining

their global competitiveness

in science and technology.

The pharmaceutical industry,

for example, has turned to the

use of private, non-academic

research groups such as contract

research organizations (CROs),

which can perform the work

at a lower cost than academic

institutions. With cuts to federal

and state government funding

sources for scientific research,

entities are looking to endowed

charities as an alternative

source of funding for scientists.

Historically, philanthropic

funding of scientific research

in the U.S. has been particularly

generous, with organizations

such as the Carnegie Institution

for Science and The Rockefeller

Foundation funding much of the

nation’s early scientific research.

Today, organizations like the Bill

and Melinda Gates Foundation

are carrying on this tradition.

And even though government

funding sources are facing an

uncertain future, there remain

avenues for federal funding

in the areas of health, energy,

science and technology for

early-stage companies that meet

certain criteria.

a publication of

List of all current federal grants.www.grants.gov

The National Science Foundation provides grants for small business-es focused on advanced materials and manufacturing, biotechnol-ogy, chemical-based technolo-gies, electronics and information technologies.www.nsf.gov/funding

The U.S. Department of Energy provides grants and loan guaran-tees to commercial entities whose work is associated with renewable energy and energy efficiency, ad-vanced transmission and distribu-tion technologies.www.lgprogram.energy.gov

The National Institutes of Health offers numerous grants in all fields of health and medical research.www.grants.nih.gov/grants

Other non-profit organizations such as the American Cancer So-ciety, the American Association for Cancer Research, and the Ameri-can Heart Association provide grants for biomedical research. www.cancer.orgwww.aacr.orgwww.americanheart.org

States also can be resources for grants and loans such as the Cali-fornia Institute for Regenerative Medicine and the California Clean Energy Fund. www.cirm.ca.gov/grantswww.calcef.org

The Arthritis Foundation offers grants to fund innovative research programs that meet the mission of the foundation.www.arthritis.org/research

University systems such as Uni-versity of California System and Stanford University can be sources of research grants.www.ucop.edu/researchwww.med.stanford.edu

The A.P. Giannini Fellowship Program supports early-stage investigators of innovative medical research in the basic and applied sciences.www.apgianninifoundation.org

The National Ataxia Foundation funds research for new and in-novative studies in pathogenesis or treatment of the hereditary or sporadic nervous system disorders or diseases.www.ataxia.org/research/naf-research-landing.aspx

The Burroughs Wellcome Fund annually awards grants to quali-fied candidates in the fields of mathematics, physics, chemistry, computer science, statistics or engineering.www.bwfund.org/pages/52/Grant-Programs

The Pharmaceutical Research and Manufacturers of America Founda-tion provides grants related to the optimal development of drug-delivery products and devices. www.phrmafoundation.org/awards/pharmaceutics/postdoc.php

The National Venture Capital Asso-ciation has thousands of members nationwide that can be a source of funding for research.www.nvca.org/members.html

Export working capital financing is a way for exporters to obtain funding through unique loans to purchase goods and services they need to successfully export their company’s technology or products. Several banks provide this type of financing, and the Export-Import Bank of the United States and the U.S. Small Business Administration offer programs to guarantee these loans on behalf of U.S. exporters.www.exim.govwww.sba.gov

Entrepreneur groups can be a source of industry support for early-stage research and develop-ment. They offer introduction to like-minded individuals, op-portunities to share problem-solving strategies, and advice on profitability and funding sources. Examples include the Bio2Device Group, the eWomenNetwork, the SVForum, the Keiretsu Forum and the VCTaskforce, to name just a few.www.biodevicegroup.orgwww.ewomennetwork.comwww.svforum.orgwww.keiretsuforum.comwww.vctaskforce.com

Finally, product development groups offer services to market, develop and distribute products, some offering profit-sharing opportunities in lieu of fees for services. They include Azopharma Product Development Group; Integrated Product Development Group; Product Development Group, LLC; the Quest Develop-ment Group; and the Slingshot Product Development Group. www.qdgnet.comwww.slingshotpdg.com

Alternative Research Funding Sources:

HKS Science & Technology provides comprehensive strategic science planning services in addition to laboratory programming, planning and design. Through our internal knowledge base and association with external subject matter experts, we assist scientific research clients by identifying the political, economic, social and technological landscape under which they operate, determine their position within the market, benchmark their position relative to peer institutions, assess inefficiencies in their existing operations and facilities, and develop a roadmap to establish a more-efficient approach to achieving their research objectives with less capital outlay.

HKS Science & Technology sets the stage for scientific discovery

by providing the broadest range of services available to the academic and biomedical research communities, as well as to the biotechnology, pharmaceutical and medical device industries. Our facilities for science are enhancing the human experience by inspiring creativity and innovation, fostering collaboration among colleagues and peers, and attracting and retaining the best and brightest talent. Demonstrating HKS Science & Technology’s commitment to achieving excellence in laboratory programming, planning and design, the firm acquired the world-renowned laboratory planning practice known for years in the industry as Earl Walls Associates. Today, the group

has been rebranded as HKS Earl Walls Associates, a studio of HKS, Inc. With more than 2,500 laboratories to its credit, totaling over 200 million gross square feet, the practice grew from the 1962 collaboration among Dr. Jonas Salk, architect Louis I. Kahn and founder Earl Walls. For the past five decades the practice has been integral to the development and innovation of many of the world’s modern laboratory planning concepts, 22 of which have been recognized by R&D Magazine’s “Laboratory of the Year” competition.

ONE WAY FOR SCIENTISTS TO ADDRESS A POTENTIAL SHORTFALL IN RESEARCH FUNDING IS TO THINK STRATEGICALLY ABOUT THEIR SCIENTIFIC MISSION AND DEVELOP MORE-EFFICIENT OPERATIONS AND FACILITIES IN WHICH TO CONDUCT THEIR RESEARCH.

HKS Science & Technology

left to rightGenomics Institute of the Novartis Research Foundation, La Jolla, CaliforniaWilliams College Unified Sciences Center, Williamstown, Massachusetts

a publication of

Instituto de Diagnóstico y Referencia Epidemiológicos (InDRE) Infectious Disease Laboratories, México City, México

Designing to Make a Difference

Imagine our world in the year 1912 when the U.S. economy was based on industrial manufacturing and agriculture. The first Keystone Cops movie debuted, the Girl Scouts were formed, the Titanic catastrophe occurred, and automobile drivers in Detroit were the first to experience the traffic light. The inventions of the day included plastic, the electric blanket, and the first motorized movie camera. Oreo cookies were created, the tallest structure in the world was the Eiffel Tower, and telephones looked like candlesticks. Here we are, 100 years later, carrying telephones in our pockets that provide immediate access to the Internet. The world is now at our fingertips, and it is a very different place because of science and technology.

I have focused my career on the design of facilities that help to change and shape our world. Not only are science buildings technically complex, but each one is distinctly different. For example, the issues involved in designing

a facility for forensic analysis are completely different from those associated with academic or biomedical

research. And each has its own unique criteria for what is required to allow our clients to achieve

success and to foster collaboration and innovation. At HKS, we design facilities for

science that enhance the human experience in order to attract and retain top scientists,

administrators, technicians, staff and students by providing the broadest

range of programming, planning and design services available.

Back in 1912, the life expectancy for the average

male in America was 48 years; today it is 75. This dramatic difference is a result of advances in medicine and healthcare delivery that is directly

attributable to scientific research. Knowing that the

facilities we design today will lead to the scientific discoveries

of the future is extremely rewarding. It’s gratifying to be a part of the scientific life cycle where the facilities we plan and design can help make a difference in people’s lives.

with H. MICHAEL SMITH, AIA, LEED APSENIOR VICE PRESIDENT, NATIONAL SCIENCE & TECHNOLOGY LEADER, HKS, INC.

Design Link

See video of Mike speaking aboutScience & Technology design by following

this link with your smart device

a publication of

Printed in the USA on environmentally responsible and sustainable paper with 100% of the fiber from independently certified, well-managed forests, or controlled wood manufactured with electricity in the form of renewable energy (wind, hydro, and biogas) and includes a minimum of 30% post-consumer recovered fiber.

HKS Science & Technology LEADERSHIP TEAM:

H. Michael Smith, AIA, LEED APSenior Vice President, National Science & Technology Practice Leaderhmsmith@hksinc.comWith more than 28 years of experience in a wide range of renovation, adaptive reuse and new construction projects, Michael Smith has directed, managed, programmed and designed academic and biomedical research laboratories, pharmaceutical production facilities, cleanrooms for medical device manufacturers and animal research facilities, among others.

Ken DeBoer, AIAVice President, Senior Laboratory Plannerkdeboer@hksinc.comKen DeBoer is an experienced laboratory programmer, planner and designer with a complete understanding of the complex laboratory planning and technical systems design issues. He also has a working knowledge of the business and operational issues influencing laboratory facilities design and how expenditures for human resources, operations, equipment and energy far exceed the capital construction costs.

Ned MichalowskiVice President, Senior Laboratory Plannernmichalowski@hksinc.comNed Michalowski has over 30 years of experience in the planning and design of institutional, government and private-industry laboratory facilities. He has served as programmer and project manager on projects for such notable clients as Ciba-Geigy Pharmaceuticals in Summit, New Jersey and the Novartis Institute for Functional Genomics in San Diego, California.

Dave McGlashan, RAVice President, Senior Science & Technology Architectdmcglashan@hksinc.comDuring his 26-year career, Dave McGlashan has completed more than 5 million square feet of facilities for pharmaceutical, biotechnology, medical device and semiconductor industry clients, as well as public and private research institutions and the federal government. He focuses on all aspects of the planning and design of laboratories and vivariums, as well as pilot and sustained production facilities.

Sources: Scientific American, July 2012 | Nature Cell Biology, May 2012 | USA Today, March 2011 | Nature News, August 2011 | Chemistry World, September 2010 | Carr & Ferrell, LLP, 2008 | National Science Board, 1997

hksarchitects@hksinc.comwww.hksinc.com

1919 McKinney A

ve.D

allas, Texas | 75201

ww

w.hksinc.com

Creating Places that Enhance the H

uman Experience

Abu D

habi

Atlanta

Chennai

Chicago

Dallas

Denver

Detroit

Fort Myers

Fort Worth

Indianapolis

Las Vegas

London

Los Angeles

Mexico C

ity

Miam

i

Nashville

New

Delhi

New

York

Orange C

ounty

Orlando

Palo Alto

Phoenix

Richmond

Salt Lake City

San Diego

San Francisco

Sao Paulo

Shanghai

Tampa

Washington, D

.C.