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Histology Questions
1. The extracellular matrix and the cytoskeleton communicate
across the cell membrane through which
one of the following?
A. Proteoglycans
B. Integrins
C. Cadherins
D. Intermediate filaments
Answer: B.
2. Which one of the following is absent in smooth muscle cells
compared to skeletal muscle cells?
A. Troponin
B. Calmodulin
C. Calcium
D. Myosin light-chain kinase
E. Actin and myosin interactions
Answer: A. Smooth muscle cell is the least specialized type of
muscle and contains no troponin.
3. Which of the following cells is specifically targeted in
multiple sclerosis that affects the anterior
corpus callosum,?
A. Microglia
B. Oligodendrocytes
C. Astrocytes
D. Schwann cells
E. Axons of multipolar neurons
Answer: B. Since it specifically points to a central nervous
system location, the myelin sheath in this
region is produced by oligodendrocytes and are the ones
primarily affected in MS.
4. Organs such as the brain and thymus have a more effective
blood barrier because their blood
capillaries are which of the following types?
A. Continuous type with few vesicles
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B. Fenestrated type with diaphragms
C. Fenestrated type without diaphragms
D. Discontinuous type with diaphragms
E. Discontinuous type without diaphragms
Answer: A
5. Which one of the following lung findings would one expect to
find that is characteristic of severe
congestive heart failure?
A. Type 1 pneumocyte containing hemosiderin granules
B. Type 2 pneumocyte containing surfactant
C. Macrophages containing hemosiderin granules
D. Erythrocytes
E. Fibroblasts containing type I procollagen
Answer: C.
6. In using a tuning fork to evaluation the vibration sense of a
patient, which of the following sensory
receptors is primarily tested?
A. Ruffini endings
B. Pacinian corpuscle
C. Meissner corpuscle
D. Merkel corpuscle
E. Free nerve endings
Answer: B. Ruffini endings: stimulated by mechanical stress.
Meissner: texture, Merkel: two point
discrimination. Free nerve endings: light pressure and
touch.
7. Which of the following structures is found only in the renal
medulla?
A. Proximal convoluted tubules
B. Distal convoluted tubules
C. Collecting ducts
D. Afferent arterioles
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E. Thin loops of Henle
Answer: E.
8. The retinal pigment epithelium is characterized by which of
the following?
A. The presence of the photoreceptor (rod and cone)
perikarya
B. Phagocytosis of worn-out components of photoreceptor
cells
C. Origin from the inner layer of the optic cup during embryonic
development
D. Presence of amacrine cells
E. Synthesis of aqueous humor
Answer: B.
9. The portion of the junctional complex primarily responsible
for restricting the passage of molecules
between adjacent epithelial cells:
A. Zonula occludens
B. Zonula adherens
C. Macula adherens
D. Hemidesmosomes
Answer: A.
10. What is the space between the liver sinusoids and the
hepatocytes called?
a. Space of Disse
b. Space of Mall
c. Vacuole
d. Lacuna
e. Howship's lacuna
Answer: A.
