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Helene Gayle
Director, HIV, TB and Reproductive Health
Bill and Melinda Gates Foundation
HIV/AIDS in the African American Community:Confronting the Challenge
HIV/AIDS Challenges
• Continuing spread in Africa, Caribbean• Emerging epidemics• Possible resurgence in high income countries• Anticipated escalation of new infections
– 45 million new infections by 2010– 28 million infections are preventable
Western Europe
570 000570 000North Africa & Middle East
550 000550 000Sub-Saharan
Africa
29.4 29.4 millionmillion
Eastern Europe & Central Asia
1.2 million1.2 million
South & South-East Asia
6 million6 million
Australia & New Zealand
15 00015 000
North America
980 000980 000Caribbean
440 000440 000
Latin America
1.5 1.5 millionmillion
Total: 42 million
East Asia & Pacific
1.2 million1.2 million
Source: UNAIDS, December 2002
Adults and Children Estimated to be Living with HIV/AIDS, End 2002
AIDS Cases and Deaths Reported1981 – 2002, United States
DeathsCases
Adults/Adolescents 849,780 482,330
Children (<13 years) 9,220 5,342
Total 859,000 487,672
0
10
20
30
40
50
60
70
Pe
rce
nt o
f Cas
es
MSM & IDU
Men who have sex with men (MSM)
Injection drug use (IDU)
Heterosexual contact
Year of Diagnosis
Proportion of Estimated Adult/Adolescent AIDS Cases by Exposure Category and Year of Diagnosis,
1985 – 2002, United States
85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 00 01 02
0
10
20
30
40
50
60
70
Pe
rce
nt o
f Cas
es
Year of Report
Proportion of AIDS Cases, by Race/Ethnicity and Year of Report, 1985 – 2002, United
States
White, not Hispanic
Black, not Hispanic
Hispanic
Asian/Pacific Islander American Indian/Alaska Native
85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 00 01 02
• 1 in 50 African American and 1 in 160 African American women is infected with HIV
• African American men’s rates of AIDS is
8X higher than White men’s
• African American women’s rates of AIDS is
20X higher than White women’s
Source: CDC. HIV/AIDS Surveillance Report. Atlanta: US Department of Health and Human Services, Public Health Service, 2001 (Vol. 13, No. 2)
Impact on Families: Adults
Leading Causes of Death Among African Americans, 25- to 44-Years-Old,
United States, 2001*
0 500 1000 1500 2000 2500 3000 3500 4000 4500
Cancer
HIV infection
Diabetes mellitus
Unintentional injury
Homicide
Heart disease
Nephritis, nephrosis & nephrotic syndrome
SuicideCerebrovascular disease
Chronic liver disease10
123456789
* Preliminary death-certificate data for 2001
Deaths
African American Adult and Adolescent AIDS Cases By Exposure Group, 1993 to 2001
0
5
10
15
20
25
30
35
40
45
1993 1994 1995 1996 1997 1998 1999 2000 2001
MSM
Heterosexual
IDU
Source: U.S. Centers for Disease Control and Prevention. HIV/AIDS Surveillance Report. Atlanta: Department of Health and Human Services, Public Health Service, 2002 (Vols. 7-13)
Year of Report
% o
f C
ases
African American Men and Womenwith AIDS
• AIDS case rate is more than 2X higher in men than women (109.2
vs. 47.8)
• MSM is the number one mode of transmission of HIV in men (37%)
• IDU and Heterosexual activity are the number one mode of
transmission in women (39% respectively)
Source: CDC. HIV/AIDS Surveillance Report. Atlanta: US Department of Health and Human Services, Public Health Service, 2001 (Vol. 13, No. 2)
37% - 61% reported
unprotected anal intercourse in the
past 6 months
40% - 43% reported
multiple sex partners
in past 12 months
MSM Risk Behaviors amongAfrican Americans
37% - 51% reported
exchanging sex for money
or drugs
HIV Prevalence and Incidence Among 2,942 YMSM (23-29 years) in Six Cities*, 1998-2000,
United States
14
3.5
13
7
32
2.54.4
14.7
0
510
15
20
2530
35
Total White AA Latino
Per
cen
t
HIV Prevalence
HIV Incidence
* Baltimore, Dallas, Los Angeles, Miami, NYC, Seattle
Source: U.S. Centers for Disease Control and Prevention. Morbidity and Mortality Review (MMWR) 2001, 50:440-443)
74
55
93 91
7566
7871
0
20
40
60
80
100
15-22 years 23 - 29 yrs.Age Group
Per
cen
t U
naw
are
White
BlackLatino
Mixed
Proportion of HIV-Infected Young MSM Unaware of Their Infection, by Age-group and Race/Ethnicity*
*n=206 HIV-infected MSM aged 15-22 years; n=367 HIV-infected MSM aged 23-29; six US metropolitan areas, 1994-2000.
Source: U.S. Centers for Disease Control and Prevention. Morbidity and Mortality Review (MMWR) 2002, August 23: 51(33); 733-736
Up to 85% reported
inconsistent condom use
12% - 32% reported multiple
sex partners
IDU Risk Behaviors among African Americans
21%-80% reported sharing needles
Heterosexual Risk Behaviors amongAfrican Americans
74% - 88% report inconsistentcondom use
16% - 32% report multiple sex
partners in thepast 3 months
24% - 82% had been diagnosed
with an STD
Impact on Families: Youth
• 44% of AIDS cases among 13-24 year olds are African American
• 59% of cases among young men
- MSM is the number one mode of transmission in young men (60%)
• 41% of cases among young women
- Heterosexual activity is the number one mode of transmission in young women (56%)
Source: U.S. Centers for Disease Control and Prevention. National Center for HIV, STD and TB Prevention. Division of Sexually Transmitted Diseases. 2001
25% - 56% of adolescents
are sexually active
30% - 86% of adolescents
report inconsistentcondom use
High Risk Behaviors Among African American Youth
50% - 71% of adolescents report
drug or alcohol use
• Prevalence of HIV infection is 5 times greater in incarcerated populations vs. general public
(Rapposelli, et al., 2002)
• CDC cross sectional surveillance study revealed that 12% of HIV infected persons were diagnosed while incarcerated (Nakashima et al., 2002)
HIV Testing in Correctional Settings
Effective Prevention Tools
• Mass media• Voluntary counseling
and testing• Targeted peer
counseling • School-based
programs• Programs for out-of-
school youth• Workplace programs
• Condom social marketing
• Public sector condom distribution
• Harm reduction programs and drug treatment
• STD treatment• Prevention of mother to
child transmission
VCT – A Key Element in Integrating
Prevention and Care
• Gateway to care and treatment
• Has independent efficacy as prevention intervention especially in HIV-infected people
• Broader knowledge of serostatus permits the development of prevention programs that specifically target people living with HIV/AIDS
• Potential of anti retroviral therapy to reduce infectiousness
Structural Interventions
• Interventions that operate at the environmental or structural level and alter the context for individual action
• Examples:– 100% condom brothels– Closing of gay bathhouses in San Francisco– Legalizing over the counter sales of needle and
syringes in pharmacies– Increased alcohol taxes
Factors Affecting HIV Prevention
Individual micro-level factors
Structural intermediate-level factors
Structural macro-level factors
Individual level knowledge of HIV risk and prevention
Area-based treatment center and neighborhood characteristics; poverty and deprivation
Socio-economic status of populations
Individual characteristics targeted in prevention programs
Personal vulnerabilities such as knowledge and skills
Structural level laws, policies, standard operating procedures; environmental conditions and resources of individuals
Economic conditions or policies
Programmatic vulnerabilities such as education and services
Economic underdevelopment, gender inequality
Societal vulnerabilities such as discrimination of HIV-positive
Class, race, gender, sexuality inequalities
Source: Sunartojo, 2000.
Prevention Framework
Enabling Environment
Service and Commodities
Empowermentfor Prevention
Decrease in Risky Behavior
Modify Biologic Factors
Decrease in HIV
Incidence