Gamma Nbjnm anobiomimetics

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    Nano-Biomimetics

    Team

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    Nano-biomimetics?

    What is nano-biomimetics?

    Biological self-assembly

    Viral assembly Gecko Feet

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    What is nano-biomimetics?

    Utilizes biological mechanisms to create

    materials

    Mimicking biological self-assembly processes

    Using single biological units as a building block

    along with inorganic materials

    Mimics biology at the molecular level

    Synthesizing structures that mimic biological

    structures

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    Utilizing biological mechanisms

    Atom-precise manipulation yields composite

    materials and nano-scale structures with

    desirable properties

    Parallel self-assembly processes achieve

    precision with high speed and reproducibility

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    Biological self-assembly

    Bottom-up fabrication process

    Continuing miniaturization of devices in

    nanotechnology

    Nature already assembles its smallest

    components into ordered structures

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    Biological self-assembly: applications

    Genetically Engineered Proteins for Inorganics

    (GEPIs)

    Methods

    Biopatterning

    Neuron growth on patterned substrates

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    Biological self-assembly: applications

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    Viral assembly: biology

    Abalone shell mostly

    chalk, but 3000x

    stronger because of

    crystal structure Very difficult to

    assemble crystals,

    requires precise

    control in 3-D

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    Viral assembly: biomimetic

    Genetically engineered

    virus attaches to

    molecule of building

    material Viruses orient

    themselves in solution,

    producing well-ordered

    liquid crystal

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    Viral assembly: applications

    Procedure can easily scale up

    Multiple applications

    Better materials

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    Mimicking biological structures

    Top-down approach using lithography,

    scanning probes, CVD, sputter coating, and

    many other techniques normally unassociated

    with biology

    Requires very precise manipulation

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    Gecko feet: biology

    Millions of hairs

    called setae

    Fiber radius is

    nanometer-scale Adhesion due to

    van der Waals

    and capillary

    forces

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    Gecko feet: biomimetic

    Use electron beam

    lithography and dry

    etching to create

    synthetic polymer hairs Attach to flexible base

    Palm-sized piece can

    support a human

    QuickTime and a

    TIFF (LZW) decompressorare needed to see this picture.

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    Gecko feet: applications

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    Nano-biomimetics!

    Create materials with novel properties

    Synthesize existing bio-materials in larger

    quantities

    Integrate biomolecules and materials with

    inorganic ones for hybrid systems

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    References

    Bio-assembly

    Sarikaya, Mehmet. "Moleucular biomimetics: nanotechnology through biology. Nature Materials Sept. 2003.

    Gyorvary, Erika S. "Biomimetic Nannostructure Fabrication: Nanolithographic Lateral Patterning and Self-Assemblyof Functional Bacterial S-Layers at Silicon Supports." 11 Dec. 2002. Nano Letters. Vol. 3. 2004. 315+

    Zhang, Shuguang. "Fabrication of novel biomaterials through molecular self-assembly." Nature biotechnology Oct.2003.

    Quinion, Michael. "Turns of Phrase: Biomimetics." World Wide Words. 22 Nov. 1997..

    Viral Assembly:

    http://www.sunlandimports.com http://www.sciencemag.org/cgi/content/full/296/5569/892

    http://www.pnas.org/cgi/content/full/100/12/6946

    http://web.mit.edu/giving/spectrum/fall05/building_on_nature.html

    http://pubs.acs.org/cgi-bin/sample.cgi/nalefd/2004/4/i01/html/nl0347536.html

    Gecko foot:

    http://www.andrew.cmu.edu/user/gshah/Project_modeling.htm

    http://photos.wildmadagascar.org/images/uroplatus_fimbriatus-0143.shtml

    http://www.houstonvoice.com/2004/6-18/view/actionalert/action.cfm http://onnes.ph.man.ac.uk/nano/Publications/Naturemat_2003.pdf

    Spiderman: http://spiderman.sonypictures.com