The patient’s choice for clinical research

Finding enough Inflammatory Bowel Disease (IBD) patients for clinical trials has become a major challenge in the crowded U.S. and Western European markets.

India is an ideal new source of patients for your IBD studies

A vast population in need of healthcareThe majority of India’s more than 1.3 billion people are biologic naïve patients or patients with inadequate response on current treatments.

A significantly improved and predictable regulatory environment Intellectual property protections and approval timelines are in line with Eastern Europe’s.

An IBD disease burden similar to the West Eight years ago, the overall estimated IBD population was 1.4 million, which was the second highest number after the U.S. and one of the largest across the globe.

IBD

pop

ulat

ion

(1x

10%

)

USA

1.64

0.050.13

0.03

0.55

1.4

Sweden Japan China IndiaSouth Korea

1.8

1.6

1.4

1.2

1.0

0.8

0.6

0.4

0.2

0

Source: karger.com

If you need a new source of patients for your IBD clinical trials.

Turn to IndiaPaving the way to successful clinical research in India

7885_SynexusIndiaBrochure_190x260mm_6pp_v8_online.indd 1-2 17/09/2018 10:47

SynexusThe largest global network of wholly-owned sites, providing patient recruitment, trial planning, management and patient retention

S4 India

Extensive local access to patients• India’s IBD standard of care ensures patients will align with protocol requirements • Our integrated approach accelerates local patient recruitment and improves patient retention• Local and global patient-centric operations enables scale-up as needed

Two specialty companies committed to the recruitment and retention of high-quality clinical research patients in India

Synexus and S4 can give you the competitive advantage you need

Together, we deliver the IBD patients and experienced sites you need

The local partner with in-depth country-specific knowledge of site and patient recruitment in India

+ =

Immediate access to India’s established clinical research infrastructure • Pool of 400+ experienced and highly qualified investigators• Network of 57 high quality sites, including 12 that specialize in gastroenterology • State-of-the-art facilities with on-site endoscopy • Experience in 15 CD and 32 UC studies

400+experienced

highly qualifiedinvestigators

Acceleratedlocal patientrecruitment

57High quality

sites

12Sites specializing

in gastroenterology

Onsiteendoscopy

Experiencein 15 CDstudies

Experience in32 UC studies

Local and global

patient-centric operations

Rapid start-up and streamlined

process

Improvedpatient

retention

Centralized project

management and robust feasibility

All-inclusive guidance

through study conduct

7885_SynexusIndiaBrochure_190x260mm_6pp_v8_online.indd 3-4 17/09/2018 10:47

Together, we pave the way for your IBD studies

All-inclusive guidance through study conduct• Up-to-date on submission processes and regulations • In-depth understanding of the healthcare system and patient flow• Versed on practical issues such as investigator selection, language, and cultural nuances

Rapid start-up and streamlined processes• Robust feasibility for evidence-based solutions • Proven Synexus quality management system• Standardized project management and SOPs • Cost efficiencies with one contract

High-quality data • Hand-picked affiliated sites with extensive experience • Consistency of study conduct across every site• Metrics-driven approach to study delivery• Dedicated ground staff supporting sites and quality oversight• Track record of successful sponsor and regulatory audits

All-inclusive guidance

Rapid start-up

High quality data

Take advantage of the emerging

IBD clinical research opportunities in India

An ideal source for

IBD patients

Partner with Synexus today US +1 480 820 5656 | UK +44 1257 230723 Email bd@synexus.com | Visit synexus.com

With it’s vast population, major IBD burden, improved regulatory environment and strong research infrastructure, the Indian market is now emerging as an ideal source for IBD patients.

Together, Synexus and S4 can pave the way.

We can partner with you immediately in the planning and execution of a successful IBD clinical trial in India.

Contact us today to schedule a meeting

The patient’s choice for clinical research

7885_SynexusIndiaBrochure_190x260mm_6pp_v8_online.indd 5-6 17/09/2018 10:47