Quick- Easy manipulation in only 2 steps- Semi-quantitative result within 10 minutes- Titration procedure available

Clinical studies- Evaluated by the NRC for Invasive Mycoses and Antifungals (Pasteur Institute, Paris) *- Evaluated by the Department of Clinical Microbiology and Infectious Diseases at the University of the Witwatersrand (Johannesburg), Sriruttan C et al., ECCMID, 2016

Traceability - Compatibility with Biosynex® Reader for results recording- Positive and negative controls included

BIOSYNEX® CryptoPS

M Y C O L O G Y

For the semi-quantitative detection ofCryptococcus sp. antigens

in whole blood, serum, plasma and CSF

Positive

• T1 line appears at 25 ng/mL capsular antigen• T2 line appears at 2,5 µg/mL capsular antigen

CT2T1

CT2T1

CT2T1

BIOSYNEX SA22 Boulevard Sébastien Brant

67400 ILLKIRCH-GRAFFENSTADEN - FrancePhone : +33 3 88 77 57 52 - Fax : +33 3 59 81 21 74

E-mail : client.pro@biosynex.comwww.biosynex.com FL

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THE SOLUTIONCryptotoccosis is an opportunistic and cosmopolitan disease caused by Cryptococcus neoformans. Infection occurs most often in childhood and by inhalation of spores. Cryptococcosis is the second leading cause of death in immunocompromised patients (HIV, transplants). The most common clinical expression of the disease is meningoencephalitis. There are approximately 1 million new cases each year worldwide including 625,000 deaths from cryptococcal meningitis (source: CDC). The vast majority of cases occur in Sub-Saharan Africa (> 70%), followed by Asia. BIOSYNEX® CryptoPS is a rapid immunochromatographic test for the semi-quantitative detection and titration of Cryptococcus sp. capsular antigens in serum, plasma, whole blood and CFS to guide the diagnosis of cryptococcal infections, especially in cases of meningitis.

• Automated reading of the results• Storage of the results• Printer, barcode reader and adhesive paper• LIS connectivity

Kit content

• 20 test cassettes• 20 pipettes (20 µL)• 1 dropper bottle of diluent• 1 bottle of diluent for the titration procedure• 1 bottle of positive control• Barcode card for test lot identi� cation when using BIOSYNEX® Reader

Procedure for semi-quantitative detection*

Biosynex® Reader

Product references

Bibliography

PerformancesBIOSYNEX®

CryptoPS

Speci� city 100%

Sensitivity 95%

• Ref. 1120001 - BIOSYNEX CryptoPS - 20 tests

• Ref. 5060001 - Biosynex® Reader - 1 reader

* Temfack E, et al., 2018, Front. Microbiol. 9:409.

Carefully read the instructions on the labellingand / or reagent and instrument notices.

1 2 3

Compared to another commercial rapid test.Internal study (voir notice).

CompatibleBIOSYNEX®

Reader

Results

* Titration procedure available on user instructions.

20µL

BIOSYNEX

opTricon Gesellschaft für optische Technologien (GERMANY)

Transfer 20 µL of sample (whole blood / serum / plasma / CSF) into

the well of the test cassette.

Add 3 drops of diluent. Read the result at 10 minutes, visually or using the Biosynex® Reader.

Negative

10