wwwMedChemExpresscom 1

Flavonoids

Flavonoids (or bioflavonoids) are a class of plant and fungussecondary metabolites Chemically flavonoids have the generalstructure of a 15-carbon skeleton which consists of two phenyl rings(A and B) and heterocyclic ring (C) This carbon structure can beabbreviated C6-C3-C6 They can be classified into flavonoids orbioflavonoids isoflavonoids neoflavonoids Flavonoids are widelydistributed in plants fulfilling many functions Flavonoids are themost important plant pigments for flower coloration producingyellow or redblue pigmentation in petals designed to attractpollinator animals In higher plants flavonoids are involved in UVfiltration symbiotic nitrogen fixation and floral pigmentation They

may also act as chemical messengers physiological regulators and cell cycle inhibitors In addition some flavonoidshave inhibitory activity against organisms that cause plant diseases

Purity 970Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

100 mg

Purity 9885Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9991Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg

Purity 9991Clinical Data Phase 4Size 10mM x 1mL in DMSO

50 mg 100 mg

Purity 9916Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9857Clinical Data Phase 4Size 10mM x 1mL in DMSO

5 mg 10 mg 25 mg 50 mg

Purity 9900Clinical Data Phase 2Size 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Purity 9998Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9998Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9922Clinical Data Phase 4Size 10mM x 1mL in DMSO

100 mg

Flavonoids Inhibitors amp Modulators

Bioactivity (+)-Catechin hydrate inhibits cyclooxygenase-1 ( ) withCOX-1an of 14 μMIC50

Bioactivity (+)-Kavain a main kavalactone extracted from Piper has anticonvulsive properties attenuatingmethysticum

vascular smooth muscle contraction through interactions withvoltage-dependent Na and Ca channels (+)-Kavhellip+ 2+ [1]

Bioactivity (-)-Catechin gallate is a minor constituent in green teacatechins (-)-Catechin gallate inhibits the activity of

and enzymesCOX-1 COX-2

Bioactivity (-)-Epicatechin inhibits cyclooxygenase-1 ( ) with anCOX-1 of 32 μM (-)-Epicatechin inhibits the IL-1β-inducedIC50

expression of iNOS by blocking the nuclear localization of thep65 subunit of NF-κB

Bioactivity Epicatechin gallate inhibits cyclooxygenase-1 ( ) withCOX-1an of 75 μMIC50

Bioactivity (-)-Epigallocatechin (EGCG) is the most abundant flavonoid ingreen tea can bind to unfolded native polypeptides andprevent conversion to amyloid fibrils

Bioactivity (-)-Epigallocatechin Gallate is a tea flavonoid with potentantioxidant antiinflammatory and anticarcinogenicproperties (-)-Epigallocatechin Gallate is reported toinhibit signaling and thereby exert anticancer effectsEGFR

Bioactivity (-)-Gallocatechin gallate is the polyphenol isolated from teawith cancer-preventive activities

Bioactivity 2-O-Rhamnosylicariside II is a flavonoid glycoside compoundand might be beneficial for improving postmenopausalosteoporosis

Bioactivity 2-Hydroxyacetophenone is found in alcoholic beverages2-Hydroxyacetophenone is present in tomato cassia friedbeef rum whiskey cocoa coffee and black tea2-Hydroxyacetophenone is a flavouring ingredient Buildingblock in chemical synthesis

2 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom

(+)-Catechin hydrate Cat No HY-N0355

(+)-Kavain Cat No HY-B1671

(-)-Catechin gallate ((-)-Catechin 3-gallate (-)-Catechin 3-O-gallate) Cat No HY-N0356

(-)-Epicatechin ((-)-Epicatechol Epicatechin epi-Catechin) Cat No HY-N0001

(-)-Epicatechin gallate (ECG Epicatechin gallate (-)-Epicatechin 3-O-gallate) Cat No HY-N0002

(-)-Epigallocatechin (EGC Epigallocatechin l-Epigallocatechin) Cat No HY-N0225

(-)-Epigallocatechin Gallate (EGCG Epigallocatechol Gallate) Cat No HY-13653

(-)-Gallocatechin gallate ((-)-Gallocatechol gallate) Cat No HY-N0522

2-O-Rhamnosylicariside II Cat No HY-N2289

2-Hydroxyacetophenone (o-Hydroxyacetophenone o-Acetylphenol) Cat No HY-Y1426

wwwMedChemExpresscom 3

Purity 9982Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

50 mg

Purity gt98Clinical Data No Development ReportedSize 2 mg 5 mg

Purity 9985Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

100 mg

Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg

Purity 9987Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

1 mg 5 mg 10 mg

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

100 mg

Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg

Purity gt98Clinical Data No Development ReportedSize 5 mg

Purity 9820Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

100 mg

Purity 9975Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg

Bioactivity 3-Methoxypuerarin (3-MOP) is an isoflavone extracted fromradix that shows neuron protection activitypuerariae

Bioactivity 34-Dihydroxyflavone (34-DHF) is an oral active flavonoidwith antiviral activity against Influenza A virus [1]

Bioactivity 374-Trihydroxyflavone isolated from Rhus javanica var is a flavonoid with DNA strand-scission activityroxburghiana

[1]

Bioactivity 47-Dimethoxyisoflavone is isolated from the leaves of which shows antifungal activityAlbizzia lebbeck

Bioactivity 5a-Pregnane-320-dione is the endogenous progesteronemetabolite

Bioactivity 6rdquo-O-Apiosyl-5-O-Methylvisammioside is one of the componentsof the traditional Chinese medicine Kang-Jing

Bioactivity 6-O-Malonylgenistin(Malonylgenistin) is an isoflavonederivative

Bioactivity 6-methylflavone is an activator of α β γ and α β 1 2 2L 1 2 receptorsGABAA

Bioactivity The compound 74-Di-O-methylapigenin may be partlyresponsible for the reported antifungal activity of Czeyheri and may serve as a potential source of lead compoundsthat can be developed as antifungal phytomedicines

Bioactivity 7-Hydroxychromone is a inhibitor with an ofSrc kinase IC50lt300 μM

3-Methoxypuerarin Cat No HY-N1978

34-Dihydroxyflavone (34-DHF) Cat No HY-111802

374-Trihydroxyflavone (5-Deoxykampferol) Cat No HY-111806

47-Dimethoxyisoflavone (Dimethoxydaidzein) Cat No HY-N2145

5a-Pregnane-320-dione Cat No HY-W006492

6-O-Apiosyl-5-O-Methylvisammioside Cat No HY-N2295

6-O-Malonylgenistin (Malonylgenistin Genistin malonate) Cat No HY-N0917

6-Methylflavone Cat No HY-N6630

74-Di-O-methylapigenin (47-Dimethoxy-5-Hydroxyflavone) Cat No HY-N2144

7-Hydroxy-4-chromone (7-Hydroxychromone) Cat No HY-N6596

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

100 mg

Purity 9964Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9943Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg 25 mg 50 mg 100 mg

Purity 9883Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg

Purity 9988Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

2 mg 5 mg 10 mg 25 mg 50 mg

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg 200 mg 500 mg

Purity 990Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg

Purity 9980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg 50 mg 100 mg

Purity 9843Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg

Purity 9981Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

100 mg

Bioactivity 7-Methoxyisoflavone is an isoflavone derivative and also anactivator of adenosine monophosphate-activated protein kinase( )AMPK

Bioactivity 1) Natural acacetin was a 40-fold and 55-fold more potentinhibitor of BACE-1 than oleanolic acid and maslinic acidrespectively[1] 2) Acacetin significantly suppressed thephotoreceptor collapse [1] 3) Acacetin significantly reducesthe Aβ levels by interfering with human APP proteolytichellip

Bioactivity Amentoflavone is a natural biflavone compound with manybiological properties including anti-inflammatoryantioxidative and neuroprotective effects IC50 valueTarget In vitro In irradiated v79 cells Pretreatment withamentoflavone 24 hours prior to 8 Gy 60Co γ-ray irradiationhellip

Bioactivity Anemarsaponin E is extracted from Anemarrhena asphodeloidesBunge and has anti-inflammatory activity

Bioactivity Apigenin is a competitive inhibitor with a of 2 μMCYP2C9 Ki Bioactivity Apigenin-7-glucoside exhibits significant anti-proliferativeand antioxidant activity scavengers of ROS In vitroexhibits significant anti-proliferative activity againstB16F10 melanoma cells after 24 and 48 h of incubationApigenin-7-glucoside provoks an increase of subG0G1 S andhellip

Bioactivity Apigenin-7-glucuronide could inhibit Matrix Metalloproteinases activities with of 1287 2239 1752 027(MMP) IC s50

μM for MMP-3 MMP-8 MMP-9 MMP-13 respectively

Bioactivity Astilbin a flavonoid compound is isolated from the rhizomeof Astilbin enhances activationSmilax glabra NRF2Astilbin also suppresses expression and TNF-α NF-κBactivation

Bioactivity Astragalin (kaempferol-3-O-glucoside) is a flavonoid withanti-inflammatory activity and newly found in persimmon leavesand green tea seeds

Bioactivity Baicalein (567-Trihydroxyflavone) is a xanthine oxidaseinhibitor with an value of 312 mMIC50

4 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom

7-Methoxyisoflavone Cat No HY-N6631

Acacetin (57-Dihydroxy-4-methoxyflavone) Cat No HY-N0451

Amentoflavone (Didemethyl-ginkgetin) Cat No HY-N0662

Anemarsaponin E Cat No HY-N0813

Apigenin (457-Trihydroxyflavone Apigenol CI Natural

Yellow 1) Cat No HY-N1201

Apigenin 7-glucoside (Apigenin-7-O-β-D-glucopyranoside Apigetrin Cosmosiin) Cat No HY-N0578

Apigenin-7-glucuronide (Apigenin 7-O-glucuronide) Cat No HY-N1454

Astilbin Cat No HY-N0509

Astragalin (Astragaline 3-Glucosylkaempferol Kaempferol

3-β-D-glucopyranoside) Cat No HY-N0015

Baicalein (567-Trihydroxyflavone) Cat No HY-N0196

wwwMedChemExpresscom 5

Purity 9803Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg 50 mg 100 mg

Purity 9871Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg 50 mg

Purity 9990Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg

Purity 9886Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

200 mg 500 mg

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg

Purity 9962Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9956Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg

Purity 9985Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9896Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg 50 mg

Purity 9801Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

100 mg 500 mg 1 g 5 g

Bioactivity Baicalin is a flavonoid glycoside isolated from Scutellaria Baicalin reduces the expression of baicalensis NF-κB

Bioactivity Baohuoside I a flavonoid isolated from Epimedium koreanum acts as an inhibitor of downregulates CXCR4Nakai CXCR4

expression induces apoptosis and shows anti-tumor activity

Bioactivity Bavachalcone is a major bioactive compounds isolated fromPsoralea corylifolia L has been widely used as traditionalChinese medicine antibiotic or anticancer agent

Bioactivity Bavachin a flavonoid first isolated from seeds of P acts as a phytoestrogen that activates thecorylifolia

estrogen receptors ERα and ERβ with s of 320 and 680 nMEC50respectively

Bioactivity Bavachinin(7-O-Methylbavachin) is a natural compound isolatedfrom the Chinese herb Fructus Psoraleaehas potentanti-angiogenic activity IC50 value Target in vitroIsobavachalcone significantly inhibits both oligomerizationand fibrillization of Aβ42 whereas bavachinin inhibitshellip

Bioactivity beta-Mangostin is a natural product

Bioactivity Biochanin A is a naturally occurring fatty acid amidehydrolase ( ) inhibitor which inhibits FAAH with sFAAH IC50of 18 14 and 24 μM for mouse rat and human FAAHrespectively

Bioactivity Calycosin (Cyclosin) is a natural active compound withanti-oxidative and anti-inflammation activity

Bioactivity Calycosin-7-O-β-D-glucoside a melanin biosynthesis inhibitoris isolated from the methanol extract of astragalus IC50value 68 μM in inhibition of Tyrosinase Target In vitroCalycosin-7-O-β-d-glucoside showed a melanin biosynthesisinhibition zone in a culture plate of Streptomyceshellip

Bioactivity Cardamonin is a novel antagonist of cation channelhTRPA1with an of 454 nMIC50

Baicalin (Baicalein 7-O-β-D-glucuronide) Cat No HY-N0197

Baohuoside I (Icariin-II Icariside-II) Cat No HY-N0011

Bavachalcone (Broussochalcone B) Cat No HY-N0231

Bavachin (Corylifolin) Cat No HY-N0233

Bavachinin (7-O-Methylbavachin Bavachinin A) Cat No HY-N0234

beta-Mangostin (β-Mangostin) Cat No HY-N0941

Biochanin A (4-Methylgenistein Olmelin) Cat No HY-14595

Calycosin (Cyclosin) Cat No HY-N0519

Calycosin-7-O-β-D-glucoside Cat No HY-N0520

Cardamonin (Alpinetin chalcone Cardamomin) Cat No HY-N1378

Purity 9766Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg 50 mg 100 mg

Purity 9972Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9975Clinical Data No Development ReportedSize 5 mg 10 mg

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity gt98Clinical Data No Development ReportedSize 250 mg 500 mg

Purity gt98Clinical Data No Development ReportedSize

Purity 9931Clinical Data No Development ReportedSize 5 mg

Purity 9922Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

1 g

Purity 990Clinical Data Phase 4Size 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Purity 9844Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg

Bioactivity Casticin is a methyoxylated flavonol isolated from Viticis with antimitotic and anti-inflammatory effectFructus

Casticin inhibits the activation of STAT3

Bioactivity Catechin inhibits cyclooxygenase-1 ( ) with an ofCOX-1 IC5014 μM

Bioactivity Chrysin is one of the most well known blockersestrogen Bioactivity Chrysin-7-O-glucuronide is a flavonoid extracted from with antioxidant activity Scutellaria baicalensis [1]

Bioactivity Chrysin-7-O-β-D-glucuronide is a flavonoid [1] Bioactivity Cirsiliol is a potent and selective inhibitor5-lipoxygenaseand a competitive low affinity benzodiazepine receptor ligand

Bioactivity Complanatuside is a flavonoid found in the traditional Chinesemedicine Semen Astragali Complanati

Bioactivity Corylifol A inhibits IL-6-induced activation andSTAT3phosphorylation with an of 081 μMIC50

Bioactivity Corylin is a major bioactive compound isolated from Psoraleacorylifolia L antibiotic or anticancer compound

Bioactivity Cynaroside is a flavone a flavonoid-like chemical compoundIt is a 7-O-glucoside of luteolin

6 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom

Casticin (Vitexicarpin) Cat No HY-N0516

Catechin ((+)-Catechin Cianidanol Catechuic acid) Cat No HY-N0898

Chrysin (57-Dihydroxyflavone) Cat No HY-14589

Chrysin-7-O-glucuronide Cat No HY-N2376

Chrysin-7-O-β-D-glucuronide Cat No HY-111812

Cirsiliol Cat No HY-110399

Complanatuside Cat No HY-N1444

Corylifol A (Corylifol-A Corylinin) Cat No HY-N0897

Corylin Cat No HY-N0236

Cynaroside (Luteolin 7-glucoside Luteolin 7-O-β-D-glucoside) Cat No HY-N0540

wwwMedChemExpresscom 7

Purity 9988Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9943Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg

Purity gt98Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

100 mg

Purity 9888Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg 50 mg 100 mg

Purity 980Clinical Data LaunchedSize 10mM x 1mL in DMSO

50 mg

Purity 9988Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

50 mg 100 mg 200 mg

Purity 9954Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg 100 mg

Purity 9956Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg

Purity 9904Clinical Data Phase 1Size 10mM x 1mL in DMSO

10 mg 50 mg 100 mg 200 mg 500 mg

Purity 9966Clinical Data Phase 4Size 10mM x 1mL in DMSO

500 mg 1 g 5 g 10 g

Bioactivity Daidzein is a soy isoflavone which acts as a activatorPPAR Bioactivity Daidzin is an isoflavone that has anti-oxidantanti-carcinogenic and anti-atherosclerotic activitiesdirectly inhibits mitochondrial aldehyde dehydrogenase 2 (IC50= 80 nM) and is an effective anti-dipsotropic isoflavone

Bioactivity Deguelin a naturally occurring rotenoid is a potent PI3KAKTinhibitor

Bioactivity Dihydromyricetin is a potent inhibitor with an of 48 μMIC50on Dihydromyricetin can activatedihydropyrimidinaseautophagy through inhibiting signalingmTORDihydromyricetin suppresses the formation of mTOR complexes (

)mTORC1 2

Bioactivity Diosmetin is a natural flavonoid which inhibits human CYP1Aenzyme activity with an of 40 μM in HepG2 cellIC50

Bioactivity Diosmin is a flavonoid found in a variety of citrus fruits andalso an agonist of the ( )aryl hydrocarbon receptor AhR

Bioactivity Engeletin is a flavanonol glycoside isolated from hymenaea inhibits signaling-pathway activation andmartiana NF-κB

possesses anti-inflammatory analgesic diuresisdetumescence and antibiosis effects

Bioactivity Enocyanin is an anthocyanin extracted from grapes Enocyaninshows inhibitory effect on the leucine aminopeptidase acidphosphatase γ-glutamyl transpeptidase and esterase activity

[1]

Bioactivity Epimedin A is a natural compound extracted from HerbaEpimedii

Bioactivity Epimedin A1 is a flavonoid extracted from Herba Epimedii whichis one of commonly used Chinese medicines

Daidzein Cat No HY-N0019

Daidzin (Daidzoside NPI-031D Daidzein 7-O-glucoside) Cat No HY-N0018

Deguelin ((-)-Deguelin (-)-cis-Deguelin) Cat No HY-13425

Dihydromyricetin (Ampeloptin Ampelopsin) Cat No HY-N0112

Diosmetin Cat No HY-N0125

Diosmin Cat No HY-N0178

Engeletin Cat No HY-N0436

Enocyanin Cat No HY-114336

Epimedin A Cat No HY-N0257

Epimedin A1 (Hexandraside F) Cat No HY-N0258

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg 100 mg 200 mg

Purity 9968Clinical Data Phase 4Size 10mM x 1mL in DMSO

100 mg 500 mg

Purity 950Clinical Data Phase 4Size 10mM x 1mL in DMSO

1 g 5 g

Purity 9996Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg 25 mg 50 mg 100 mg

Purity 9969Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg 200 mg 500 mg

Purity 9802Clinical Data Phase 2Size 10mM x 1mL in DMSO

100 mg 500 mg 1 g

Purity 9901Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg 50 mg

Purity 9998Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg

Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg

Purity 9932Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg

Bioactivity Epimedin B a component extracted from Epimedii Folium isreported to have antiosteoporotic activity

Bioactivity Epmedin C a natural product has estrogen-like effects forovariectomized mice

Bioactivity Eriodictyol is a flavonoid isolated from the Chinese herbwith antioxidant and anti-inflammatory activity Eriodictyolinduces signaling pathwayNrf2

Bioactivity Eupatilin a lipophilic flavonoid isolated from Artemisiaspecies is a agonist and possesses anti-apoptoticPPARαanti-oxidative and anti-inflammatory activities

Bioactivity Fisetin is a natural flavonol found in many fruits andvegetables with various benefits such as antioxidantanticancer neuroprotection effects

Bioactivity Formononetin (Formononetol Flavosil) is a bioactive componentextracted from the red clover inhibits the proliferation ofDU-145PC-3 cells in a dose-dependent manner

Bioactivity Galangin is an agonistantagonist ofthe arylhydrocarbon receptor and also showsinhibition of activityCYP1A1

Bioactivity Gastrodenol(Bismuth tripotassium dicitrate De-Noltab)is amineral that is used in treating ulcers and upset stomach

Bioactivity Genistein a soy isoflavone is a multiple tyrosine kinasesinhibitor which acts as a chemotherapeutic agent againstdifferent types of cancer mainly by altering apoptosis thecell cycle and angiogenesis and inhibiting metastasis

Bioactivity Genistin is the major isoflavonoid of soybeans and soyproducts

8 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom

Epimedin B Cat No HY-N0259

Epmedin C (Epimedin-C Baohuoside-VI) Cat No HY-N0260

Eriodictyol (Huazhongilexone) Cat No HY-N0637

Eupatilin Cat No HY-N0783

Fisetin Cat No HY-N0182

Formononetin (Biochanin B Flavosil Formononetol) Cat No HY-N0183

Galangin (Norizalpinin 357-Trihydroxyflavone) Cat No HY-N0382

Gastrodenol (Bismuth tripotassium dicitrate Bismuth subcitrate) Cat No HY-B0796

Genistein (NPI 031L) Cat No HY-14596

Genistin (Genistine Genistoside Genistein

7-O-β-D-glucopyranoside) Cat No HY-N0595

wwwMedChemExpresscom 9

Purity gt98Clinical Data No Development ReportedSize

Purity 9933Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg 50 mg

Purity gt98Clinical Data No Development ReportedSize 5 mg

Purity 9700Clinical Data Phase 3Size 10mM x 1mL in DMSO

10 mg 50 mg 100 mg 200 mg 500 mg 1 g

Purity 9804Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

50 mg

Purity 9942Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg 50 mg

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9998Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9982Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg

Bioactivity Genkwanin is a major non-glycosylated flavonoid withanti-flammatory activities

Bioactivity Ginkgetin is a natural biflavonoid isolated from leaves ofGinkgo biloba L effects of anti-inflammation and anticancerhave been reported IC50 value Target in vitro Ginkgetininhibits COX-2 dependent phases of prostaglandin D(2) (PGD(2))generation in bone marrow-derived mast cells (BMMC) in ahellip

Bioactivity Glabridin is a natural isoflavan from bindsGlycyrrhiza glabrato and activates with an of 6115 nM GlabridinPPARγ EC50exhibits antioxidant anti-bacterial anti-nephriticanti-diabetic anti-fungal antitumor anti-inflammatoryantiosteoporotic cardiovascular protective neuroprotectivehellip

Bioactivity Glycitein is a soybean (yellow cultivar) isoflavonoid used incombination with other isoflavonoids such as genistein anddaidzein to study apoptosis and anti-oxidation processes

Bioactivity Glycitin is a natural isoflavone isolated from legumespromotes the proliferation of bone marrow stromal cells andosteoblasts and suppresses bone turnover

Bioactivity Hesperetin is a natural flavanone and acts as a potent andbroad-spectrum inhibitor against human activityUGT

Bioactivity Hesperidin (HP) is a bioflavonoid that plays a role in plantdefense and is abundant in citrus species such as grapefruitlemon and orange Hesperidin is used effectively as asupplemental agent in complementary therapy protocols sinceit possesses biological and pharmacological properties as anhellip

Bioactivity Hexamethylquercetagetin is a polymethoxylated flavone in peelsof citrus cultivars

Bioactivity Hispidulin is a natural flavone with a broad spectrum ofbiological activities Hispidulin is a Pim-1 inhibitor with an

of 271 μMIC50

Bioactivity Homomangiferin isolated from the leaves of L isM indicamangiferin monomethyl ether Homomangiferin has importantmedicinal properties and is widely used to relieve manysymptoms for example coughing and asthma [1]

Genkwanin (Puddumetin) Cat No HY-N0731

Ginkgetin Cat No HY-N0889

Glabridin Cat No HY-N0393

Glycitein (Glycetein) Cat No HY-N0016

Glycitin (Glycitein 7-O-β-glucoside) Cat No HY-N0012

Hesperetin Cat No HY-N0168

Hesperidin (Hesperetin 7-rutinoside) Cat No HY-15337

Hexamethylquercetagetin (Hexa-O-methylquercetagetin

Quercetagetin hexamethyl ether hellip) Cat No HY-N4308

Hispidulin (Dinatin) Cat No HY-N1950

Homomangiferin Cat No HY-111811

Purity 9959Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9921Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

1 g 5 g

Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg

Purity 9927Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg

Purity 9881Clinical Data Phase 2Size 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9836Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg

Purity 9875Clinical Data Phase 3Size 10mM x 1mL in DMSO

100 mg 200 mg 500 mg

Purity 9805Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg 50 mg

Purity 9981Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg 50 mg

Bioactivity Homoplantaginin is a flavonoid from a traditional Chinesemedicine with antiinflammatory and antioxidantSalvia plebeiaproperties Homoplantaginin could inhibit and mRNATNF-α IL-6expression and phosphorylationIKKβ NF-κB

Bioactivity Hydroxysafflor yellow A is a flavonoid derived and isolatedfrom traditional Chinese medicine Carthamus tinctorius Lpossesses anti-tumor activity

Bioactivity Icariin is a flavonol glycoside Icariin inhibits andPDE5 activities with s of 432 nM and 7350 μMPDE4 IC50

respectively Icariin also is a activatorPPARα

Bioactivity Icariside I is a metabolite of Icarlin which could regulatebone remodeling and is recognized as an effective agent forthe treatment of osteoporosis

Bioactivity Icaritin(Anhydroicaritin) is a component of Epimediumflavonoid isolated from Herba Epimedii enhances osteoblasticdifferentiation of mesenchymal stem cells (MSCs) while itinhibits adipogenic differentiation of MSCs by inhibitingPPAR-g pathway IC50 value Target in vitro Icaritin washellip

Bioactivity IKarisoside A(Icarisoside-A) is a natural compound isolatedfrom Epimedium koreanum (Berberidaceae) has anti-inflammatoryproperties

Bioactivity Ikarisoside F is a flavonol glycoside from Vancouveriahexandra could bind to AdoHcy hydrolase

Bioactivity Ipriflavone is a synthetic isoflavone derivative used tosuppress bone resorption

Bioactivity Isobavachalcone(Corylifolinin) is a chalcone constituent ofAngelica keiskei induces apoptosis in neuroblastoma IC50value Target Isobavachalcone inhibits platelet aggregationInhibitor of Epstein-Barr virus early antigen (EBV-EA)induction Isobavachalcone exhibits potent inhibitory effecthellip

Bioactivity Isoginkgetin is a MMP-9 inhibitor also a Pre-mRNA SplicingInhibitor with IC 50 of 30 uM target MMP-9 [1] Pre-mRNASplicing [2] IC 50 30 u M (Pre-mRNA Splicing) In vitroIsoginkgetin inhibits HT1080 tumor cell invasionsubstantially Isoginkgetin is also quite effective inhellip

10 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom

Homoplantaginin Cat No HY-N1949

Hydroxysafflor yellow A (Safflomin A HSYA) Cat No HY-N0567

Icariin (Ieariline) Cat No HY-N0014

Icariside I (Icarisid I) Cat No HY-N1939

Icaritin (Anhydroicaritin) Cat No HY-N0678

IKarisoside A (Icarisoside-A Baohuoside II) Cat No HY-N0875

Ikarisoside F (Ikarisoside-F Icarisoside-F) Cat No HY-N0861

Ipriflavone Cat No HY-N0094

Isobavachalcone (Corylifolinin Isobacachalcone) Cat No HY-13065

Isoginkgetin Cat No HY-N2117

wwwMedChemExpresscom 11

Purity 9999Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

1 mg 5 mg 10 mg 25 mg

Purity 9894Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg

Purity gt98Clinical Data No Development ReportedSize 5 mg

Purity 9897Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

1 mg 5 mg 10 mg 25 mg

Purity 9817Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg

Purity 9800Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg 50 mg

Purity 9997Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Purity 9924Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

1 mg 5 mg 10 mg 25 mg 50 mg

Purity 9985Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9824Clinical Data Phase 1Size 10mM x 1mL in DMSO

10 mg 50 mg 100 mg 200 mg

Bioactivity Isoliquiritigenin is an anti-tumor flavonoid from the root of which inhibits with an Glycyrrhiza glabra aldose reductase IC50

of 320 nM

Bioactivity Isomangiferin a natural product is reported to haveantiviral activity

Bioactivity Isoorientin is a potent inhibitor of with an valueCOX-2 IC50of 39 μM

Bioactivity Isoquercitrin is an effective antioxidant and an eosinophilicinflammation suppressor

Bioactivity Isorhamnetin is a flavonoid compound extracted from theChinese herb L IsorhamnetinHippophae rhamnoidessuppresses skin cancer through direct inhibition of MEK1and PI3K

Bioactivity Isosakuranetin is a flavanone flavonoid which can be found inthe fruit of Citrus bergamia

Bioactivity Isosilybin (Isosilybinin) is a flavonoid from milk thistleinhibits induction with an of 74 μMCYP3A4 IC50

Bioactivity Isotanshinone I has inhibitory activity against α-glucosidaseand formation of with of 113 0432 μM forAGE IC s50α-glucosidase and AGE respectively

Bioactivity Isovitexin is a flavonoid isolated from rice hulls of Oryza possesses anti-inflammatory and anti-oxidantsativa

activities Isovitexin acts like a inhibitor andJNK12inhibits the activation of NF-κB

Bioactivity Jaceosidin is a flavonoid isolated from Artemisia vestitainduces apoptosis in cancer cells activates andBaxdown-regulates Mcl-1 and c-FLIP expression Jaceosidin[1]

exhibits anti-cancer anti-inflammatory activitihellip[2]

Isoliquiritigenin (GU17 ISL Isoliquiritigen) Cat No HY-N0102

Isomangiferin Cat No HY-N0772

Isoorientin (Homoorientin) Cat No HY-N0767

Isoquercitrin (Isoquercitroside Isoquercetin) Cat No HY-N0768

Isorhamnetin (3-Methylquercetin) Cat No HY-N0776

Isosakuranetin Cat No HY-N2131

Isosilybin (Isosilybinin) Cat No HY-N0779

Isotanshinone I Cat No HY-N6649

Isovitexin (Saponaretin Homovitexin) Cat No HY-N0773

Jaceosidin Cat No HY-N0831

Purity 9949Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg

Purity gt98Clinical Data No Development ReportedSize

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg

Purity 9972Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg 100 mg

Purity 9630Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

2 mg 5 mg 10 mg 25 mg

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

2 mg 5 mg 10 mg 25 mg

Purity 9947Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

50 mg 100 mg 200 mg 500 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg

Purity 9850Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

1 mg 5 mg

Bioactivity Juglanin is a activatorJNK Bioactivity Kaempferide is an O-methylated flavonol a type of chemicalcompound It can be found in Kaempferia galanga (aromaticginger) The enzyme kaempferol 4-O-methyltransferase usesS-adenosyl-L-methionine and kaempferol to produceS-adenosyl-L-homocysteine and kaempferide P-glycoproteins

Bioactivity Kaempferitrin is a natural flavonoid possessesantinociceptive anti-inflammatory anti-diabetic antitumoraland chemopreventive effects and activates signalinginsulinpathway

Bioactivity Kaempferol inhibits expression in breastestrogen receptor αcancer cells and induces apoptosis in glioblastoma cells andlung cancer cells by activation of MEK-MAPK

Bioactivity Kuromanin (chloride) extracted from mulberry leaves has beenshown to improve blood glucose concentrations and lipidhomeostasis and to reduce obesity

Bioactivity Kuwanon A is a flavone derivative isolated from the root barksof the mulberry tree ( ) inhibits nitric oxideMorus alba Lproduction with an of 105 μMIC50

Bioactivity Licochalcone A a flavonoid isolated from the famous Chinesemedicinal herb Glycyrrhiza uralensis Fisch presents obviousanti-cancer effects The IC50 value is 097 μM for UGT1A1

Bioactivity Licochalcone C could inhibit with ofα-glucosidase IC s50lt100 nM and 9243 μM for α-glucosidase and protein tyrosinephosphatase 1B (PTP1B) respectively

Bioactivity Ligustroflavone extracted from is aLigustrum lucidumpotential candidate as calcium-sensing receptor (CaSR)antagonist Ligustroflavone exhibits protective effectsagainst diabetic osteoporosis in mice [1]

Bioactivity Liquiritigenin a flavanone isolated from Glycyrrhiza uralensisis a highly selective estrogen receptor β ( ) agonist withERβan of 365 nM for activation of the ERE tk-LucEC50

12 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom

Juglanin Cat No HY-N3442

Kaempferide (Kaempferol 4-O-methyl ether) Cat No HY-15449

Kaempferitrin (Lespedin Lespenephryl) Cat No HY-N0628

Kaempferol (Robigenin Kempferol) Cat No HY-14590

Kuromanin chloride (Chrysontemin Cyanidin 3-O-glucoside chloride) Cat No HY-N0640

Kuwanon A Cat No HY-N2300

Licochalcone A (Licochalcone-A) Cat No HY-N0372

Licochalcone C Cat No HY-N0374

Ligustroflavone (Nuezhenoside) Cat No HY-N0546

Liquiritigenin (47-Dihydroxyflavanone) Cat No HY-N0377

wwwMedChemExpresscom 13

Purity 9908Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

2 mg 5 mg 10 mg 25 mg

Purity 9970Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

1 mg 5 mg 10 mg 25 mg 50 mg

Purity 9984Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg

Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg

Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 25 mg

Purity 9814Clinical Data Phase 2Size 10mM x 1mL in DMSO

10 mg 50 mg 100 mg 500 mg

Purity 9999Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg

Purity 9976Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg

Purity 9807Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg 50 mg 100 mg

Bioactivity Liquiritin is a flavonoid isolated from acts as anGlycyrrhizaantioxidant and has neuroprotective anti-cancer andanti-inflammatory activity [1] [2]

Bioactivity Loureirin A is a flavonoid extracted from Dragons Blood caninhibit phosphorylation and has antiplatelet activityAkt

Bioactivity Loureirin B a flavonoid extracted from Dracaena is an inhibitor of plasminogen activatorcochinchinensis

inhibitor-1 with an IC of 2610μM Loureirin B(PAI-1) 50also inhibits the phosphorylation of and KATP ERK JNK

Bioactivity Luteolin (Luteolol) is a falconoid compound which exhibitsanticancer properties

Bioactivity Luteolin 7-O-glucuronide could inhibit MatrixMetalloproteinases activities with of 1763(MMP) IC s50799 1142 1285 003 μM for MMP-1 MMP-3 MMP-8 MMP-9MMP-13 respectively

Bioactivity Luteolin-3-O-beta-D-glucuronide is a luteolin glucosiduronicacid consisting of luteolin having a beta-D-glucosiduronicacid residue attached at the 3-position

Bioactivity Luteolin-7-rutinoside has both anti-arthritic and antifungalactivities can result in a combination therapy for thetreatment of fungal arthritis due to infectionC albicans

Bioactivity Mangiferin is a activator Mangiferin suppresses nuclearNrf2translocation of the subunits and NF-κB p65 p50

Bioactivity Miquelianin (Quercetin 3-O-glucuronide) is a metabolite ofquercetin and a type of natural flavonoid

Bioactivity Morusin is a prenylated flavonoid isolated from M australiswith various biological activities such as antitumorantioxidant and anti-bacteria property Morusin could inhibit

and activityNF-κB STAT3

Liquiritin Cat No HY-N0376

Loureirin A Cat No HY-N1505

Loureirin B Cat No HY-N1504

Luteolin (Luteolol Digitoflavone Luteoline) Cat No HY-N0162

Luteolin 7-O-glucuronide (Luteolin 7-glucuronide) Cat No HY-N1463

Luteolin-3-O-beta-D-glucuronide Cat No HY-N4099

Luteolin-7-rutinoside Cat No HY-N6647

Mangiferin Cat No HY-N0290

Miquelianin (Quercetin 3-O-glucuronide Quercetin 3-glucuronide) Cat No HY-13930

Morusin (Mulberrochromene) Cat No HY-N0622

Purity 9904Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg 100 mg

Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg

Purity 9804Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

100 mg 500 mg 1 g 5 g

Purity 9510Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

50 mg 100 mg 500 mg 1 g 5 g

Purity 9996Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9963Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

100 mg 500 mg 1 g 5 g

Purity 9979Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

200 mg 10 g

Purity 9872Clinical Data Phase 1Size 10mM x 1mL in DMSO

100 mg 500 mg 1 g 5 g

Purity 9941Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

50 mg 100 mg 200 mg 500 mg

Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 25 mg

Bioactivity Mulberrin is a strong inhibitor of organic anion-transportingpolypeptide 2B1 (OATP2B1)-mediated estrone-3-sulfate (E3S)uptake with an value being 18plusmn15 μMIC50

Bioactivity Myricetin is a common plant-derived flavonoid with a widerange of activities including strong anti-oxidant anticancerantidiabetic and anti-inflammatory activities

Bioactivity Naringenin is the predominant flavanone in grapefruitdisplays strong anti-inflammatory and antioxidant activities

Bioactivity Naringin is a major flavanone glycoside obtained fromtomatoes grapefruits and many other citrus fruits Naringinexhibits biological properties such as antioxidantanti-inflammatory and antiapoptotic activities

Bioactivity Naringin Dihydrochalcone is an artificial sweetener derivedfrom naringin Naringin is a major flavanone glycosideobtained from tomatoes grapefruits and many other citrusfruits Naringin exhibits biological properties such asantioxidant anti-inflammatory and antiapoptotic activitieshellip

Bioactivity Neobavaisoflavone an isoflavone isolated from Psoraleacorylifolia has striking anti-inflammatory and anti-cancereffects IC50 value 4293 μM (toward CCRF-CEM cells) 11464μM [against HCT116 (p53(++)) cells] [2] Target In vitro Inthe cancer cells neobavaisoflavone sensitizes human U373MGhellip

Bioactivity Neohesperidin is a flavonoid compound found in high amounts inPoncirus trifoliata with anti-oxidant and anti-inflammatoryeffects

Bioactivity Neohesperidin dihydrochalcone is a synthetic glycosidechalcone is added to various foods and beverages as a lowcaloric artificial sweetener

Bioactivity Nicotiflorin is a flavonoid glycoside extracted from atraditional Chinese medicine NicotiflorinFlos Carthamishows potent activity and neuroprotectionantiglycationeffects

Bioactivity Nobiletin is a citrus flavonoid with anti-inflammatoryanti-cancer cholesterol lowering memory protectionactivities

14 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom

Mulberrin (Kuwanon C) Cat No HY-N3513

Myricetin (Cannabiscetin) Cat No HY-15097

Naringenin Cat No HY-N0100

Naringin (Naringoside) Cat No HY-N0153

Naringin Dihydrochalcone (Naringin DC) Cat No HY-N0119

Neobavaisoflavone Cat No HY-N0720

Neohesperidin (Hesperetin 7-O-neohesperidoside) Cat No HY-N0101

Neohesperidin dihydrochalcone (Neohesperidin DC NHDC) Cat No HY-N0154

Nicotiflorin Cat No HY-N1475

Nobiletin Cat No HY-N0155

wwwMedChemExpresscom 15

Purity 9940Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

1 mg 5 mg 10 mg 25 mg

Purity 9992Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

1 mg 5 mg 10 mg

Purity gt98Clinical Data No Development ReportedSize

Purity gt98Clinical Data No Development ReportedSize

Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg

Purity 9926Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg

Purity 9533Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

1 g 5 g

Purity gt98Clinical Data No Development ReportedSize 5 mg

Purity 9990Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9996Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Bioactivity Ononin is an isoflavonoid is an additional growth inhibitorin soils associated with the weed Pluchea lanceolata

Bioactivity Oroxylin A is a natural active flavonoid with stronganticancer effects IC50 value Target In vitro Oroxylin Asuppressed the MDM2-mediated degradation of p53 viadownregulating MDM2 transcription in wt-p53 cancer cells [1]Oroxylin A remarkably reduced the generation of lactate andhellip

Bioactivity Osajin is the major bioactive isoflavone present in the fruitof with antitumor antioxidant andMaclura pomiferaanti-inflammatory activities

Bioactivity Phlorizin is a non-selective inhibitor with s of 300SGLT Kiand 39 nM for and respectively Phlorizin ishSGLT1 hSGLT2also a inhibitorNa K -ATPase+ +

Bioactivity Pinocembrin ((+)-Pinocoembrin) is a flavonoid found inpropolis acts as a competitive inhibitor of histidine

and is an effective anti-allergic agent withdecarboxylaseantioxidant antimicrobial and anti-inflammatory properties

[1]

Bioactivity Podocarpusflavone A is a DNA topoisomerase I inhibitor havemoderated anti-proliferative activity induce cell apoptosis inMCF-7 is developing anti-tumor drugs target DNAtopoisomerase I In vitro podocarpusflavone-A show significantinhibitions against DLD KB MCF-7 HEp-2 tumor cell lineshellip

Bioactivity Procyanidin A1 (Proanthocyanidin A1) is a procyanidin dimerwhich inhibits degranulation downstream of protein kinase Cactivation or Ca influx from an internal store in RBL-2132+

cells Procyanidin A1 has antiallergic effects [1]

Bioactivity Procyanidin A2 is a flavonoid found in cranberries andlingonberries with anti-cancer antioxidant antimicrobialand anti-inflammation activity [1] [2]

Bioactivity Procyanidin B1 is a polyphenolic flavonoid isolated fromcommonly eaten fruits binds to complex and hasTLR4MD-2anti-inflammatory activity

Bioactivity Procyanidin B2 is a natural flavonoid with anti-cancerantioxidant activities

Ononin (Ononoside Formononetin 7-O-β-D-glucopyranoside) Cat No HY-N0270

Oroxylin A (Baicalein 6-methyl ether 6-Methoxybaicalein) Cat No HY-N0560

Osajin (CID 95168 NSC 21565) Cat No HY-N3125

Phlorizin (Floridzin NSC 2833) Cat No HY-N0143

Pinocembrin ((+)-Pinocoembrin Dihydrochrysin Galangin flavanone) Cat No HY-N0575

Podocarpusflavone A Cat No HY-N2198

Procyanidin A1 (Proanthocyanidin A1) Cat No HY-N2344

Procyanidin A2 Cat No HY-N2343

Procyanidin B1 Cat No HY-N0795

Procyanidin B2 (Proanthocyanidin B2) Cat No HY-N0796

Purity 9953Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

PurityClinical Data No Development ReportedSize 10mM x 1mL in DMSO

50 mg

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 g 10 g

Purity 980Clinical Data LaunchedSize 10mM x 1mL in DMSO

5 g 10 g

Purity 970Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg 50 mg

Purity 9912Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg 100 mg

Purity 980Clinical Data Phase 4Size 10mM x 1mL in DMSO

1 g 5 g

Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg

Purity 9814Clinical Data Phase 2Size 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Purity gt98Clinical Data No Development ReportedSize

Bioactivity Procyanidol B4 ((-)-Procyanidin B4) is a flavanol isolatedfrom Anti-inflammatory properties Litchi chinensis [1]

Bioactivity Puerarin an isoflavone extracted from is aRadix puerariae receptor antagonist5-HT2C

Bioactivity Quercetagetin (6-Hydroxyquercetin) is the major flavonoidisolated from ( ) peel QuercetagetinCitrus unshiu C unshiu [1]

is a moderately potent and selective cell-permeable pim-1kinase inhibitor ( 034 μM) Anti-inflammatory hellipIC50

[2]

Bioactivity Quercetin a natural flavonoid is a stimulator of recombinant and also a inhibitor with of 24plusmn06 μM 30plusmn00SIRT1 PI3K IC50

μM and 54plusmn03 μM for PI3K γ PI3K δ and PI3K β respectively

Bioactivity Quercitrin is a natural compound found in Tartary buckwheatwith a potential anti-inflammation effect that is used totreat heart and vascular conditions IC50 value Target Invitro There were significant increases in caspase-3 activityloss of MMP and increases in the apoptotic cell population inhellip

Bioactivity Reynoutrin (Quercetin-3-D-xyloside) is a flavonoid from with antioxidant andPsidium cattleianum

radical-scavenging activity [1]

Bioactivity Rutin a naturally occurring flavonoid glycoside hasantioxidant anti-inflammatory anti-allergic anti-angiogenicand antiviral properties

Bioactivity Rutin hydrate is a flavonol glycoside able to cross theblood-brain barrier and acts by inhibiting and JNK ERK12activation and activating signallingmTOR

Bioactivity Safflower yellow is extracted from the flowers of the plantsafflower ( ) and as the traditionalCarthamus tinctoriusChinese medicine it has been extensively used for thetreatment of cardio cerebrovascular diseases

Bioactivity Sagittatoside A is a natural compound isolated fromtraditional Chinese herb Yinyanghuo (Herba Epimdii)

16 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom

Procyanidol B4 ((-)-Procyanidin B4) Cat No HY-107208

Puerarin Cat No HY-N0145

Quercetagetin (6-Hydroxyquercetin) Cat No HY-N4149

Quercetin Cat No HY-18085

Quercitrin (Quercetin 3-rhamnoside) Cat No HY-N0418

Reynoutrin (Quercetin-3-D-xyloside Reinutrin) Cat No HY-N1354

Rutin (Rutoside Quercetin 3-O-rutinoside) Cat No HY-N0148

Rutin hydrate (Rutoside hydrate Quercetin 3-O-rutinoside hydrate) Cat No HY-N0148A

Safflower yellow Cat No HY-N0938

Sagittatoside A (Icariin-A) Cat No HY-N0873

wwwMedChemExpresscom 17

Purity 9893Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg 50 mg 100 mg

Purity 9815Clinical Data No Development ReportedSize 1 mg 5 mg

Purity 9922Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg

Purity 980Clinical Data LaunchedSize 10mM x 1mL in DMSO

100 mg 500 mg

Purity 9984Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

10 mg 25 mg 50 mg

Purity 9902Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

2 mg 5 mg 10 mg 25 mg 50 mg

Purity gt98Clinical Data No Development ReportedSize

Purity 980Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Purity 9874Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg

Bioactivity Sagittatoside B is a natural compound isolated fromtraditional Chinese herb Yinyanghuo (Herba Epimdii)

Bioactivity Sakuranetin is a rice flavonoid phytoalexin shows strongantifungal activity Sakuranetin has anti-inflammatory[1]

and antioxidative activities Sakuranetin amelioratesLPS-induced acute lung injury [2]

Bioactivity Schaftoside is a flavonoid found in a variety of Chineseherbal medicines such as Schaftoside inhibitsEleusine indicathe expression of TLR4 and Myd88 Schaftoside also decreasesDrp1 expression and phosphorylation and reduces mitochondrialfission [1]

Bioactivity Scutellarin a main active ingredient extracted from Erigeronbreviscapus (Vant) Hand-Mazz has been wildly used to treatacute cerebral infarction and paralysis induced bycerebrovascular diseases

Bioactivity Scutellarin an active flavone isolated from Scutellariabaicalensis can down-regulates the signalingSTAT3GirdinAktin HCC cells and inhibits RANKL-mediated MAPK and NF-κBsignaling pathway in osteoclasts

Bioactivity 6-shogaol an active compound isolated from Ginger ( Zingiber Rosc) exhibits a variety of biological activitiesofficinale

including anticancer anti-inflammation and anti-oxidation

Bioactivity Silibinin an effective anti-cancer and chemopreventive agenthas been shown to exert multiple effects on cancer cellsincluding inhibition of both cell proliferation and migrationIC50 value Target anticancer in vitro silibininsignificantly induced the expression of the non-steroidalhellip

Bioactivity Sinensetin is a methylated flavone found in certain citrusfruits pocess potent antiangiogenesis and anti-inflammatorysinensetin enhances adipogenesis and lipolysis In vitroSinensetin promots adipogenesis in 3T3-L1 preadipocytesgrowing in incomplete differentiation medium sinensetinhellip

Bioactivity Sophoflavescenol is a prenylated flavonol which shows greatinhibitory activity with of 0013 μM againstIC50

and also inhibits RLAR HRAR AGEPhosphodiesterase 5 (PDE5)BACE1 AChE and BChE with IC s of 030 microM 017 microM 17hellip50

Bioactivity Sophoricoside is an isoflavone glycoside isolated from Sophorajaponica and has anti-inflammatory anti-cancer andimmunosuppressive effects

Sagittatoside B Cat No HY-N0874

Sakuranetin Cat No HY-N3006

Schaftoside Cat No HY-N0703

Scutellarein (6-Hydroxyapigenin 4567-Tetrahydroxyflavone) Cat No HY-N0752

Scutellarin Cat No HY-N0751

Shogaol ([6]-Shogaol 6-Shogaol) Cat No HY-14616

Silibinin (Silybin Silibinin A Silymarin I) Cat No HY-13748

Sinensetin (Pedalitin permethyl ether) Cat No HY-N0297

Sophoflavescenol Cat No HY-N2284

Sophoricoside Cat No HY-N0423

Purity 980Clinical Data No Development ReportedSize 1 mg

Purity 9805Clinical Data Phase 4Size 10mM x 1mL in DMSO

100 mg 5 g

Purity 9913Clinical Data No Development ReportedSize 1 mg

Purity 9909Clinical Data No Development ReportedSize 2 mg 5 mg 10 mg 25 mg

Purity 9998Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg

Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg

Purity 9982Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

50 mg 100 mg

Purity 9910Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg 100 mg

Purity 9996Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

100 mg

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg

Bioactivity Sotetsuflavone is a potent inhibitor of DENV-NS5 RdRp (Denguevirus NS5 RNA-dependent RNA polymerase) with an IC50 of 016uM is the most active compound of this series

Bioactivity Syringaldehyde is a polyphenolic compound belonging to thegroup of flavonoids and is found in different plant specieslike and Manihot esculenta Magnolia officinalis [1]

Syringaldehyde moderately inhibits activity withhellipCOX-2

Bioactivity Tangeretin (Tangeritin) a flavonoid from citrus fruit peelshas been proven to play an important role in anti-inflammatoryresponses and neuroprotective effects in several diseasemodels and was also selected as a Notch-1 inhibitor

Bioactivity Taxifolin ((+)-Dihydroquercetin) exhibits important anti- activity Taxifolin exhibits significant inhibitorytyrosinase

activity against with an value of 1933 μMcollagenase IC50

Bioactivity Tectochrysin (Techtochrysin) is one of the major flavonoids of Miquel Tectochrysin (Techtochrysin) inhibitsAlpinia oxyphylla

activity of NF-κB

Bioactivity Tectorigenin is a plant isoflavonoid originally isolated fromthe dried flower of BenthPueraria thomsonii

Bioactivity Theaflavin is a suitable natural inhibitor against influenza A( ) neuraminidaseH1N1

Bioactivity Toxicarol isoflavone is an isoflavone extracted fromMillettia brandisiana

Bioactivity Troxerutin also known as vitamin P4 is atri-hydroxyethylated derivative of natural bioflavonoid rutinswhich can inhibit the production of (reactive oxygen species

) and depress ER stress-mediated activationROS NOD

Bioactivity Warangalone is an anti-malarial compound which can inhibit thegrowth of both strains of parasite (chloroquine3D7sensitive) and (chloroquine resistant) with s of 48K1 IC50μgmL and 37 μgmL respectively Warangalone can alsoinhibit (hellipcyclic AMP-dependent protein kinase catalytic subunit

18 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom

Sotetsuflavone Cat No HY-N2199

Syringaldehyde Cat No HY-N1390

Tangeretin (Tangeritin NSC53909 NSC618905) Cat No HY-N0133

Taxifolin ((+)-Dihydroquercetin (+)-Taxifolin) Cat No HY-N0136

Tectochrysin (Techtochrysin NSC 80687) Cat No HY-14592

Tectorigenin Cat No HY-N0792

Theaflavin Cat No HY-N0243

Toxicarol isoflavone Cat No HY-N1135

Troxerutin (Trihydroxyethylrutin) Cat No HY-N0139

Warangalone (Scandenolone) Cat No HY-N1074

wwwMedChemExpresscom 19

Purity 9801Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 25 mg 50 mg 100 mg

Purity 9968Clinical Data Phase 1Size 10mM x 1mL in DMSO

5 mg 10 mg 25 mg

Purity 9998Clinical Data No Development ReportedSize 10mM x 1mL in DMSO

5 mg 10 mg 50 mg

Bioactivity Wogonin is a naturally occurring mono-flavonoid can inhibitthe activity of and and exhibitsCDK8 Wntanti-inflammatory and anti-tumor effects

Bioactivity Xanthohumol is one of the principal flavonoids isolated fromhops the inhibitor of diacylglycerol acetyltransferase (

) and COX-2 and shows anti-cancer andDGAT COX-1anti-angiogenic activities

Bioactivity [6]-Gingerol is an active compound isolated from Ginger () exhibits a variety of biologicalZingiber officinale Rosc

activities including anticancer anti-inflammation andanti-oxidation

Wogonin Cat No HY-N0400

Xanthohumol Cat No HY-N1067

[6]-Gingerol ((S)-(+)-[6]Gingerol 6-Gingerol) Cat No HY-14615