Flavonoids - MedchemExpress.com · pathway. Purity: >98% Clinical Data: Size: 1 mg, 5 mg 3'-Demethylnobiletin Cat. No.: HY-N4127 3'-Demethylnobiletin, a derivative of Nobiletin, is

Flavonoids

Flavonoids (or bioflavonoids) are a class of plant and fungus secondary metabolites Chemically flavonoids have the generalstructure of a 15-carbon skeleton which consists of two phenyl rings (A and B) and heterocyclic ring (C) This carbon structure canbe abbreviated C6-C3-C6 They can be classified into flavonoids or bioflavonoids isoflavonoids neoflavonoids Flavonoids arewidely distributed in plants fulfilling many functions Flavonoids are the most important plant pigments for flower colorationproducing yellow or redblue pigmentation in petals designed to attract pollinator animals In higher plants flavonoids are involvedin UV filtration symbiotic nitrogen fixation and floral pigmentation They may also act as chemical messengers physiologicalregulators and cell cycle inhibitors In addition some flavonoids have inhibitory activity against organisms that cause plantdiseases

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Flavonoids Inhibitors amp Modulators

(+)-Catechin hydrateCat No HY-N0355

(+)-Catechin hydrate inhibits cyclooxygenase-1( ) with an of 14 μMCOX-1 IC50

Purity 9922Clinical Data Phase 4Size 100 mg

(+)-GallocatechinCat No HY-N0521A

(+)-Gallocatechin is a polyphenol compound fromgreen tea possesses anticancer activity

Purity 9950Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 20 mg

(+)-KavainCat No HY-B1671

(+)-Kavain a main kavalactone extracted from Piper has anticonvulsive propertiesmethysticum

attenuating vascular smooth muscle contractionthrough interactions with voltage-dependent Na+

and Ca channels2+

Purity 9998Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg

(+)-MedicarpinCat No HY-N6052

(+)-Medicarpin a pterocarpan is a type ofisoflavonoid isolated from several medicinal plantspecies with various biological effects including

andSophora japonica Zollernia paraensis Platymiscium yucatamun Machaerium

helliparistulatum

Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg

(-)-ButinCat No HY-N6020

(-)-Butin is the S enantiomer of Butin Butin is amajor biologically active flavonoid isolated fromthe heartwood of with strongDalbergia odoriferaantioxidant antiplatelet and anti-inflammatoryactivities


(-)-Catechin ((-)-Cianidanol (-)-Catechuic acid) Cat No HY-N0898A

(-)-Catechin isolated from green tea is anisomer of Catechin having a trans 2S3Rconfiguration at the chiral center Catechininhibits cyclooxygenase-1 (COX-1) with an IC of50

14 μM


(-)-Catechin gallate ((-)-Catechin 3-gallate (-)-Catechin 3-O-gallate) Cat No HY-N0356

(-)-Catechin gallate is a minor constituent ingreen tea catechins (-)-Catechin gallate inhibitsthe activity of and enzymesCOX-1 COX-2


(-)-Epicatechin ((-)-Epicatechol Epicatechin epi-Catechin) Cat No HY-N0001

(-)-Epicatechin inhibits cyclooxygenase-1 ( )COX-1with an of 32 μM (-)-Epicatechin inhibitsIC50

the IL-1β-induced expression of iNOS by blockingthe nuclear localization of the p65 subunit ofNF-κB

Purity 9900Clinical Data Phase 2Size 10 mM times 1 mL 10 mg 50 mg 100 mg

(-)-Epicatechin gallate (Epicatechin gallate ECG (-)-Epicatechin 3-O-gallate) Cat No HY-N0002

(-)-Epicatechin gallate (Epicatechin gallate)inhibits cyclooxygenase-1 ( ) with an ofCOX-1 IC50

75 μM

Purity 9857Clinical Data Phase 4Size 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg

(-)-Epigallocatechin (Epigallocatechin EGC L-Epigallocatechin) Cat No HY-N0225

(-)-Epigallocatechin (EGC) is the most abundantflavonoid in green tea can bind to unfoldednative polypeptides and prevent conversion toamyloid fibrils


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(-)-Epigallocatechin Gallate (EGCG Epigallocatechol Gallate) Cat No HY-13653

(-)-Epigallocatechin Gallate is a tea flavonoidwith potent antioxidant antiinflammatory andanticarcinogenic properties (-)-EpigallocatechinGallate is reported to inhibit signaling andEGFRthereby exert anticancer effects

Purity 9991Clinical Data Phase 4Size 10 mM times 1 mL 50 mg 100 mg

(-)-Epigallocatechin-3-(3-O-methyl) gallate ((-)-EGCG-3-O-ME) Cat No HY-N2228

(-)-Epigallocatechin-3-(3-O-methyl) gallate is anatural product isolated from the tea leaf withstrong antioxidative activity(-)-Epigallocatechin-3-(3-O-methyl) gallate hasa strong cytotoxic activity for rat cancer cells


(-)-Gallocatechin gallate ((-)-Gallocatechol gallate) Cat No HY-N0522

(-)-Gallocatechin gallate is the polyphenolisolated from tea with cancer-preventiveactivities


(2R3R)-37-Dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-met

hylbut-2-en-1-yl)chroman-4-one Cat No HY-N2296

(2R3R)-374-Trihydroxy-5-methoxy-8-prenylflavanone can be used in a flame retardant fortransparent polycarbonate products or in elevatorillumination devices research


(2S)-IsoxanthohumolCat No HY-N2584

(2S)-Isoxanthohumol is a microbial biotransformedmetabolite of the hop prenylflavanoneIsoxanthohumol

Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg

(E)-Cardamonin ((E)-Cardamomin (E)-Alpinetin chalcone) Cat No HY-N1378

(E)-Cardamonin ((E)-Cardamomin) is a novelantagonist of cation channel with an hTRPA1 IC50

of 454 nM

Purity 9981Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg

(E)-Flavokawain ACat No HY-N5106

(E)-Flavokawain A a chalcone extracted from Kavahas anticarcinogenic effect (E)-Flavokawain Ainduces apoptosis in bladder cancer cells byinvolvement of bax protein-dependent andmitochondria-dependent apoptotic pathway andsuppresses tumor growth in mice


(Rac)-HesperetinCat No HY-N0168A

(Rac)-Hesperetin is the racemate of HesperetinHesperetin is a natural flavanone and acts as apotent and broad-spectrum inhibitor against human

activity Hesperetin induces apoptosis viaUGTp38 MAPK activation


(Rac)-HydnocarpinCat No HY-N7199

(Rac)-Hydnocarpin is a flavonoid isolated from Blume and exhibitsHydnocarpus wightiana

moderate cytotoxic on cancer cells


135-TrimethoxybenzeneCat No HY-Y0678

135-Trimethoxybenzene is a key component of theChinese rose odor 135-Trimethoxybenzene issynthesized in three successive methylation stepsfrom phloroglucinol the initial precursor135-Trimethoxybenzene is an effective sedative

Purity gt98Clinical Data No Development ReportedSize 100 mg


1-Caffeoylquinic acidCat No HY-N0460

1-Caffeoylquinic acid is an effective NF-κBinhibitor shows significant binding affinity tothe RH domain of p105 with of 0002 μM andKi

binding energy of 150 Kcalmol 1-Caffeoylquinicacid has anti-oxidative stress ability


2-O-beta-L-galactopyranosylorientinCat No HY-N0406

2-O-beta-L-galactopyranosylorientin is extractedfrom the flowers of Trollius ledebouri2-O-beta-L-galactopyranosylorientin involvestransporter mediated efflux in addition to passivediffusion and is the substrate of multidrugresistance protein 2 (MRP2)


2-O-GalloylhyperinCat No HY-N0526

2-O-Galloylhyperin an active compound isolatedfrom Fisch possessesPyrola incarnateanti-oxidative and anti-inflammatory activities2-O-Galloylhyperin has hepatoprotective effectagainst oxidative stress-induced liver damage


2-O-Rhamnosylicariside IICat No HY-N2289

2-O-Rhamnosylicariside II is a flavonoidglycoside compound and might be beneficial forimproving postmenopausal osteoporosis

Purity 9885Clinical Data No Development ReportedSize 5 mg 10 mg

2-Hydroxyacetophenone (o-Hydroxyacetophenone o-Acetylphenol) Cat No HY-Y1426

2-Hydroxyacetophenone is found in alcoholicbeverages 2-Hydroxyacetophenone is present intomato cassia fried beef rum whiskey cocoacoffee and black tea 2-Hydroxyacetophenone is aflavouring ingredient Building block in chemicalsynthesis

Purity gt970Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg

34557-PentamethoxyflavoneCat No HY-N7029

34557-Pentamethoxyflavone a naturalflavonoid extracted from plantsRutaceaesensitizes chemoresistant cancer cells tochemotherapeutic drugs by inhibition of Nrf2pathway

Purity gt98Clinical DataSize 1 mg 5 mg

3-DemethylnobiletinCat No HY-N4127

3-Demethylnobiletin a derivative of Nobiletinis a polymethoxyflavonoid in citrus fruitsNobiletin exhibits anticancer activity andinhibits tumor angiogenesis by regulating SrcFAK and STAT3 signaling


3-HydroxypuerarinCat No HY-N1980

3-Hydroxypuerarin is an isoflavone isolated fromthe roots of (Willd) OhwiPueraria lobata3-Hydroxypuerarin is a antioxidant which showsmarked ONOO(-) NObull total ROS scavengingactivities


3-MethoxyflavonolCat No HY-N6629

3-Methoxyflavonol is a selective agonist of ( )neuromedin U 2 receptor NMU2R

Purity 9979Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg

3-MethoxypuerarinCat No HY-N1978

3-Methoxypuerarin (3-MOP) is an isoflavoneextracted from radix that shows neuronpuerariaeprotection activity

Purity 9975Clinical Data No Development ReportedSize 5 mg


34-Dihydroxyflavone (34-DHF) Cat No HY-111802

34-Dihydroxyflavone (34-DHF) is an oral activeflavonoid with antiviral activity against Influenza

A virus


374-Trihydroxyflavone (5-Deoxykampferol) Cat No HY-111806

374-Trihydroxyflavone isolated from Rhus is a flavonoid with DNAjavanica var roxburghiana

strand-scission activity


3567834-HeptemthoxyflavoneCat No HY-N2038

3567834-heptamethoxyflavone a flavonoidin peels exhibits anti-tumor-initiatingC unshiueffect and Anti-neuroinflammatory activity


3-DeoxysappanchalconeCat No HY-N1745A

3-Deoxysappanchalcone is a naturally-occurringchalcone compound isolated from Caesalpinia sappan

(Leguminosae) which possesses anti-allergicLantiviral anti-inflammatory and antioxidantactivities


3-O-Methylgalangin (Galangin 3-methyl ether 3-Methylgalangin) Cat No HY-N4167

3-O-Methylgalangin (Galangin 3-methyl ether) is anatural flavonoid compound from the rhizome ofAlpinia officinarum (AO) with antibacterialactivities which also inhibits pancreatic lipase


4-methyloxy-Daidzin (Daidzein 7-O-Β-D-glucoside 4-O-methylate) Cat No HY-N4128

4-methyloxy-Daidzin (Daidzein 7-O-Β-D-glucoside4-O-methylate) an isoflavone methyl-glycosideis isolated from grown onCordyceps militarisgerminated soybeans Isoflavones possessimmunomodulating and antiallergic activities


4-methyloxy-GenistinCat No HY-N4129

4-methyloxy-Genistin an isoflavonemethyl-glycoside is isolated from Cordyceps

grown on germinated soybeansmilitarisIsoflavones possess immunomodulating andantiallergic activities


45-DihydroxyflavoneCat No HY-N1881

45-Dihydroxyflavone is a andsoybean LOX-1 inhibitor with an of 1026yeast α-Glucosidase Ki

μM for soybean LOX-1 and an of 66 μM forIC50

yeast α-glucosidase LOX-1 isshort for Lectin-likeoxidized low-density lipoprotein receptor-1


47-Dimethoxyisoflavone (Dimethoxydaidzein) Cat No HY-N2145

47-Dimethoxyisoflavone is isolated from theleaves of which shows antifungalAlbizzia lebbeckactivity


47-Di-O-methylnaringeninCat No HY-N1884

47-Di-O-methylnaringenin is a flavonoidfound in Renealmia alpinia



4-HydroxychalconeCat No HY-N7056

4-Hydroxychalcone a chalcone isolated fromlicorice root with hepatoprotective activity4-Hydroxychalcone inhibits TNFα-induced NF-κBactivation via proteasome inhibition

Purity gt98Clinical DataSize 100 mg

4-MethoxychalconeCat No HY-128400

4-Methoxychalcone regulates adipocytedifferentiation through activationPPARγ4-Methoxychalcone modulates the expression andsecretion of various adipokines in adipose tissuethat are involved in insulin sensitivity


4-Methoxypuerarin (4-O-Methylpuerarin) Cat No HY-N1979

4-Methoxypuerarin (4-O-Methylpuerarin) anisoflavone diglycoside is isolated from Pueraria

lobata


4-O-MethylbavachalconeCat No HY-N1910

4-O-Methylbavachalcone is a chalcone isolatedfrom inhibits severe acutePsoralea corylifoliarespiratory syndrome coronavirus ( )SARS-CoVpapain-like protease ( ) activity with anPLpro

of 101 μMIC50


4-O-MethylochnaflavoneCat No HY-N4300

4-O-Methylochnaflavone is a biflavonoid isolatedfrom suppresses mouse lymphocyteLonicera japonicaproliferation


4-HydroxychalconeCat No HY-107818

4-Hydroxychalcone is a chalcone metabolite withanti-angiogenic and anti-inflammatory activities4-Hydroxychalcone suppresses angiogenesis bysuppression of growth factor pathway with no signsof cytotoxicity

Purity 9965Clinical DataSize 10 mM times 1 mL 100 mg

4-HydroxylonchocarpinCat No HY-N2208

4-Hydroxylonchocarpin is a chalcone compound froman extract of Psoralea corylifolia4-Hydroxylonchocarpin increases phosphorylation ofp38 MAPK JNK and ERK


4-Methylherniarin (7-Methoxy-4-methylcoumarin) Cat No HY-D0128

4-Methylherniarin (7-Methoxy-4-methylcoumarin) isa coumarin derivative and fluorescent label hasan antimicrobial activitiy against both grampositive and gram negative bacterial stains


567-Trimethoxyflavone (Baicalein trimethyl ether) Cat No HY-110398

567-Trimethoxyflavone is a novel p38-α MAPKinhibitor with an anti-inflammatory effect567-Trimethoxyflavone is isolated from severalplants including Zeyhera tuberculosa Callicarpa

and japonica Kickxia lanigera


5734-TetramethoxyflavoneCat No HY-N7030

5734-Tetramethoxyflavone one of the majorpolymethoxyflavones (PMFs) isolated from M

possesses various bioactivities includingexoticaanti-fungal anti-malarial anti-mycobacterialand anti-inflammatory activities

Purity 9908Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg


574-Trihydroxy-8-Methylflavanone (8-Methyl-naringenine) Cat No HY-N2210

574-Trihydroxy-8-Methylflavanone (Compound 2)is a flavanone isolated from Qualea grandiflora


57-DihydroxychromoneCat No HY-N1970

57-Dihydroxychromone the extract of Cudrania activates signal and exertstricuspidata Nrf2ARE

neuroprotective effects against 6-hydroxydopamine(6-OHDA)-induced oxidative stress and apoptosis


57-DimethoxyflavoneCat No HY-N5011

57-Dimethoxyflavone is one of the majorcomponents of hasKaempferia parvifloraanti-obesity anti-inflammatory andantineoplastic effects 57-Dimethoxyflavoneinhibits cytochrome P450 (CYP) 3As


56740-Tetrahydroxyisoflavone-67-di-o-b-D-glu

copyranoside Cat No HY-N6847

56740-Tetrahydroxyisoflavone-67-di-o-b-D-glucopyranoside is an isoflavonoidglycoside isolated from Pueraria lobata


573-Trihydroxy-645-trimethoxyflavoneCat No HY-N6259

573-Trihydroxy-645-trimethoxyflavone is amethylated flavones from Artemisia frigida


574-TrimethoxyflavoneCat No HY-N6818

574-Trimethoxyflavone is isolated from (KP) that is a famousKaempferia parviflora

medicinal plant from Thailand


5-Hydroxy-7-acetoxyflavoneCat No HY-N2487

5-Hydroxy-7-acetoxyflavone an active naturalflavone derivative found in various plant sourcesmodulates several biological activities


5-MethoxyflavoneCat No HY-107790

5-Methoxyflavone belonged to Flavonoid family isa DNA polymerase-beta inhibitor andneuroprotective agent against beta-amyloidtoxicity possess central nervous system (CNS)depressant effect mediated through the ionotropicGABA receptorsA


5-MethoxyPinocembrosideCat No HY-N6956

5-MethoxyPinocembroside is a flavonoid isolatedfrom Penthorumchinense Pursh


5-Methyl-7-methoxyisoflavoneCat No HY-N1993

5-Methyl-7-methoxyisoflavone is a sensationalnon-steroidal anabolic isoflavone5-Methyl-7-methoxyisoflavone shows potencyincreasing muscle mass and endurance



5-O-Demethylnobiletin (5-Demethylnobiletin) Cat No HY-N1942

5-O-Demethylnobiletin (5-Demethylnobiletin) apolymethoxyflavone isolated from Sideritistragoriganum is a direct inhibition of 5-LOX( =01 μM) without affecting the expression ofIC50

COX-2


5a-Pregnane-320-dioneCat No HY-W006492

5a-Pregnane-320-dione is the endogenousprogesterone metabolite


6-O-Apiosyl-5-O-MethylvisammiosideCat No HY-N2295

6rdquo-O-Apiosyl-5-O-Methylvisammioside is one of thecomponents of the traditional Chinese medicine

Kang-Jing


6-O-AcetylglycitinCat No HY-N4072

6-O-Acetylglycitin a acetyl glucoside is oneof the isoflavone isomer in soybeans showsvarious extents of content reduction dependent onstorage temperature packaging condition and itsisoflavone isomer kind


6-O-Malonylgenistin (Malonylgenistin Genistin malonate) Cat No HY-N0917

6-O-Malonylgenistin(Malonylgenistin) is anisoflavone derivative



62-Dihydroxyflavone is a novel antagonist ofGABA receptorA


6-Formyl-isoophiopogonanone ACat No HY-N2220

6-Formyl-isoophiopogonanone A is ahomoisoflavonoidal extracted from Ophiopogon

with antioxidant activityjaponicas


6-HydroxyflavoneCat No HY-N7110

6-Hydroxyflavone is a naturally occurring flavonewith anti-inflammatory activity 6-Hydroxyflavoneexhibits inhibitory effect towards bovinehemoglobin (BHb) glycation


6-Hydroxyluteolin 7-glucosideCat No HY-129529

6-Hydroxyluteolin 7-glucoside is a flavonoid from and Tanacetum parthenium T vulgare

6-Hydroxyluteolin 7-glucoside inhibits the majorpathways of arachidonate metabolism in leukocytes6-Hydroxyluteolin 7-glucoside hasanti-inflammatory effect


6-Methoxykaempferol 3-O-RutinosideCat No HY-N2239

6-Methoxykaempferol 3-O-Rutinoside is a naturalproduct isolated from the herbs of Pilocarpus

pennatifolius



6-MethoxytricinCat No HY-N6883

6-Methoxytricin (Compound 6) is an flavonoidisolated from Artemisia iwayomogi


6-MethylflavoneCat No HY-N6630

6-Methylflavone is an activator of α β γ and1 2 2L

α β receptors1 2 GABAA


6-FeruloylspinosinCat No HY-N2160

6-Feruloylspinosin is a flavonoid isolated fromseeds of 6-Feruloylspinosin canZiziphus jujubaacross the blood-brain barrier and enhance theexpression of GABAAα1 GABAAα5 and GABABR1 mRNAin rat hippocampal neurons


74-Di-O-methylapigenin (47-Dimethoxy-5-Hydroxyflavone) Cat No HY-N2144

The compound 74-Di-O-methylapigenin may bepartly responsible for the reported antifungalactivity of C zeyheri and may serve as apotential source of lead compounds that can bedeveloped as antifungal phytomedicines


7-Hydroxy-4-chromone (7-Hydroxychromone) Cat No HY-N6596

7-Hydroxychromone is a inhibitor withSrc kinasean of lt300 μMIC50



7-Hydroxyflavone is a flavonoid isolated from with anti-inflammatory activityM indica

7-Hydroxyflavone protects renal cells fromnicotine (NIC)-associated cytotoxicity via theERKNrf2HO-1 pathway


7-MethoxyisoflavoneCat No HY-N6631

7-Methoxyisoflavone is an isoflavone derivativeand also an activator of adenosinemonophosphate-activated protein kinase ( )AMPK


7-O-MethylmangiferinCat No HY-N2158

7-O-Methylmangifer is isolated from the cortexesof Polygala tenuifolia


8-DeoxygartaninCat No HY-N6009

8-Deoxygartanin a prenylated xanthones from G is a selective inhibitor ofmangostana

8-Deoxygartaninbutyrylcholinesterase (BChE)exhibits antiplasmodial activity with an IC of50

118 μM for the W2 strain of Plasmodiumfalciparum


8-Hydroxy-356734-hexamethoxyflavoneCat No HY-N5030

8-Hydroxy-356734-hexamethoxyflavone is apolymethoxyflavone (PMF) isolated from pericarpiumcitri reticulatae



8-PrenylnaringeninCat No HY-N2787

8-prenylnaringenin is a prenylflavonoid isolatedfrom hop cones with(Humulus lupulus)cytotoxicity


AbsinthinCat No HY-N0742

Absinthin is a structurally unique triterpene andis responsible for the high bitter value ofwormwood Absinthin is an agonist of the bittertaste receptor which reduces cytosolichTAS2R46Ca -rises induced by histamine by a2+

receptor-specific mechanism mediated by hTAS2R46


Acacetin (57-Dihydroxy-4-methoxyflavone) Cat No HY-N0451

Acacetin (57-Dihydroxy-4-methoxyflavone) was a40-fold and 55-fold more potent inhibitor ofBACE-1 than oleanolic acid and maslinic acidrespectively Acacetin(57-Dihydroxy-4-methoxyflavone) significantlysuppressed the photoreceptor collapse


AlcesefolisideCat No HY-N5049

Alcesefoliside is a flavonoid isolated from Pall with antioxidant activityNitraria sibirica


AlpinetinCat No HY-N0625A

Alpinetin is a flavonoid isolated from Alpinia activates activates katsumadai Hayata PPAR-γ

with potent anti-inflammatory activity

Purity 9907Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg

Amentoflavone (Didemethyl-ginkgetin) Cat No HY-N0662

Amentoflavone is a natural biflavone compound withmany biological properties includinganti-inflammatory antioxidative andneuroprotective effects


Anemarsaponin ECat No HY-N0813

Anemarsaponin E is extracted from Anemarrhena Bunge and has anti-inflammatoryasphodeloides

activity


Apigenin (457-Trihydroxyflavone Apigenol CI Natural

Yellow 1) Cat No HY-N1201

Apigenin is a competitive inhibitor with aCYP2C9 of 2 μMKi

Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg

Apigenin 7-glucoside (Apigenin-7-O-β-D-glucopyranoside Cosmosiin Apigetrin) Cat No HY-N0578

Apigenin-7-glucoside exhibits significantanti-proliferative and antioxidant activityscavengers of ROS In vitro exhibits significantanti-proliferative activity against B16F10melanoma cells after 24 and 48 h of incubation


Apigenin-7-glucuronide (Apigenin 7-O-glucuronide) Cat No HY-N1454

Apigenin-7-glucuronide could inhibit MatrixMetalloproteinases activities with (MMP) IC s50

of 1287 2239 1752 027 μM for MMP-3 MMP-8MMP-9 MMP-13 respectively



Apigenin-7-O-(2G-rhamnosyl)gentiobiosideCat No HY-N2153

Apigenin-7-O-(2G-rhamnosyl)gentiobioside is aflavone glycosides from Lonicera gracilipes var

glandulosa


Apigenin6-C-α-L-arabinopyranosyl-8-C-β-D-xylopyranosideCat No HY-N5128

Apigenin6-C-α-L-arabinopyranosyl-8-C-β-D-xylopyranoside is a natural flavanone compound


ApiinCat No HY-N0577

Apiin a major constituent of Apium graveolensleaves with anti-inflammatory properties Apiinshows significant inhibitory activity on nitrite(NO) production (IC = 008 mgmL) in-vitro and50

iNOS expression (IC = 0049 mg mL) in50

LPS-activated J774A1 cells


ar-Turmerone ((+)-ar-Turmerone) Cat No HY-N6703

ar-Turmerone ((+)-ar-Turmerone) is a majorbioactive compound of the herb Curcuma longawith anti-tumorigenesis and anti-inflammatoryactivities ar-turmerone ((+)-ar-Turmerone)activates apoptotic protein in human lymphoma U937cells


ArtemitinCat No HY-N3017

Artemitin is a flavonol found in Laggera pterodonta(DC) Benth with antioxidativeanti-inflammatory and antiviral activity


AstilbinCat No HY-N0509

Astilbin a flavonoid compound is isolated fromthe rhizome of Astilbin enhancesSmilax glabra

activation Astilbin also suppresses NRF2 TNF-αexpression and activationNF-κB


Astragalin (Astragaline 3-Glucosylkaempferol Kaempferol

3-β-D-glucopyranoside) Cat No HY-N0015

Astragalin (kaempferol-3-O-glucoside) is aflavonoid with anti-inflammatory activity andnewly found in persimmon leaves and green teaseeds


AstraganosideCat No HY-N4212

Astraganoside an isoflavane compound isolatedfrom the roots of (knownAstragalus membranaceusas lsquolsquoHuangqirsquorsquo)


AvicularinCat No HY-N0222

Avicularin is a bio-active flavonoid from plantsanti-inflammatory anti-allergic anti-oxidanthepatoprotective and anti-tumor activities


Baicalein (567-Trihydroxyflavone) Cat No HY-N0196

Baicalein (567-Trihydroxyflavone) is a xanthine inhibitor with an value of 312 mMoxidase IC50



Baicalin (Baicalein 7-O-β-D-glucuronide) Cat No HY-N0197

Baicalin is a flavonoid glycoside isolated from Baicalin reduces theScutellaria baicalensis

expression of NF-κB

Purity 9801Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg 1 g 5 g

Baicalin methyl esterCat No HY-N4297

Baicalin methyl ester is a constituent of theroots of S baicalmsis


Baimaside (Quercetin 3-O-sophoroside) Cat No HY-N2183

Quercetin 3-beta-sophoroside is isolated from theflowers of is an scavengers ofA venetumsuperoxide anions


Baohuoside I (Icariin-II Icariside-II) Cat No HY-N0011

Baohuoside I a flavonoid isolated from acts as an inhibitorEpimedium koreanum Nakai

of downregulates CXCR4 expression inducesCXCR4apoptosis and shows anti-tumor activity


Baohuoside VCat No HY-N2280

Baohuoside V is a flavonoid isolated from thedried herb of Epimedium davidii


Baohuoside VIICat No HY-N2290

Baohuoside VII is a flavonoid isolated from Herba with anti-osteoporosis activitiesEpimedii


Bavachalcone (Broussochalcone B) Cat No HY-N0231

Bavachalcone is a major bioactive compoundsisolated from Psoralea corylifolia L has beenwidely used as traditional Chinese medicineantibiotic or anticancer agent


Bavachin (Corylifolin) Cat No HY-N0233

Bavachin a flavonoid first isolated from seeds of acts as a phytoestrogen thatP corylifolia

activates the estrogen receptors ERα and ERβ withs of 320 and 680 nM respectivelyEC50


Bavachinin (7-O-Methylbavachin Bavachinin A) Cat No HY-N0234

Bavachinin(7-O-Methylbavachin) is a naturalcompound isolated from the Chinese herb FructusPsoraleaehas potent anti-angiogenic activity


beta-Mangostin (β-Mangostin) Cat No HY-N0941

beta-Mangostin is a natural product



Biochanin A (4-Methylgenistein Olmelin) Cat No HY-14595

Biochanin A is a naturally occurring fatty acidamide hydrolase ( ) inhibitor which inhibitsFAAHFAAH with s of 18 14 and 24 μM for mouseIC50

rat and human FAAH respectively


BlumeatinCat No HY-N2358

Blumeatin isolated from Blumea balsamiferaDC could protect liver against injury induced byCCl4 and thioacetamide (TAA)


ButinCat No HY-N6020B

Butin is a major biologically active flavonoidisolated from the heartwood of Dalbergia odoriferawith strong antioxidant antiplatelet andanti-inflammatory activities


Calycosin (Cyclosin) Cat No HY-N0519

Calycosin (Cyclosin) is a natural active compoundwith anti-oxidative and anti-inflammationactivity IC50 value Target in vitro calycosinhad obvious anti-proliferation effects on SKOV3cells in a dose- and time-dependent manner


Calycosin-7-O-β-D-glucosideCat No HY-N0520

Calycosin-7-O-β-D-glucoside a melaninbiosynthesis inhibitor is isolated from themethanol extract of astragalus


Camellianin ACat No HY-N2298

Camellianin A the main flavonoid in A nitidaleaves displays anticancer activity andangiotensin converting enzyme (ACE)-inhibitoryactivity


Camelliaside ACat No HY-N2524

Camelliaside A is a flavonoid from the methanolextract of tea ( ) seed pomaceCamellia oleifera


Camelliaside BCat No HY-N2605

Camelliaside B is a flavonoid from the methanolextract of tea ( ) seed pomaceCamellia oleifera


Cardamonin (Cardamomin Alpinetin chalcone) Cat No HY-N0279

Cardamonin (Cardamomin) a natural flavoneisolated from Hayata acts asAlpinia katsumadaian ( ) activatoraryl hydrocarbon receptor AhRCardamonin alleviates inflammatory bowel diseaseby the inhibition of NLRP3 inflammasomeactivation via an AhRNrf2NQO1 pathway


Casticin (Vitexicarpin) Cat No HY-N0516

Casticin is a methyoxylated flavonol isolated from with antimitotic andViticis Fructus

anti-inflammatory effect Casticin inhibits theactivation of STAT3



Catechin ((+)-Catechin Cianidanol Catechuic acid) Cat No HY-N0898

Catechin inhibits cyclooxygenase-1 ( ) withCOX-1an of 14 μMIC50


ChoerospondinCat No HY-N6963

Choerospondin is a flavanone isolated from thebark of Choerospondias axillaris


Chrysin (57-Dihydroxyflavone) Cat No HY-14589

Chrysin is one of the most well known estrogenblockers

Purity 9975Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g

Chrysin-7-O-glucuronideCat No HY-N2376

Chrysin-7-O-glucuronide is a flavonoid extractedfrom with antioxidantScutellaria baicalensisactivity


Chrysin-7-O-β-D-glucuronideCat No HY-111812

Chrysin-7-O-β-D-glucuronide is a flavonoid


ChrysosplenetinCat No HY-N1457

Chrysosplenetin is one of the polymethoxylatedflavonoids in L (Compositae)Artemisia annuaand other several Chinese herbs Chrysosplenetininhibits activity and reverses theP-gpup-regulated P-gp and MDR1 levels induced byartemisinin (ART)


CirsiliolCat No HY-110399

Cirsiliol is a potent and selective 5-lipoxygenaseinhibitor and a competitive low affinitybenzodiazepine receptor ligand


CirsimarinCat No HY-N7272

Cirsimarin is a potent antilipogenic flavonoidisolated from CirsimarinMicrotea debilisexerts potent antilipogenic effect and decreasesadipose tissue deposition in mice


cis-JasmoneCat No HY-N7058

Cis-Jasmone is a plant-derived natural productCis-Jasmone is constitutively released by manyflowers and sometimes by leaves as an attractantfor pollinators or as a chemical cue for hostlocation by insect flower herbivores


ComplanatusideCat No HY-N1444

Complanatuside is a flavonoid found in thetraditional Chinese medicine Semen AstragaliComplanati

Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg


Corylifol A (Corylifol-A Corylinin) Cat No HY-N0897

Corylifol A inhibits IL-6-induced STAT3activation and phosphorylation with an ofIC50

081 μM


CorylinCat No HY-N0236

Corylin is a major bioactive compound isolatedfrom Psoralea corylifolia L antibiotic oranticancer compound


Cowaxanthone BCat No HY-N6248

Cowaxanthone B is a xanthone isolated from thefruits of Cowaxanthone B has weakGarcinia cowaantibacterial activity


CratoxyloneCat No HY-N6251

Cratoxylone isolated from the bark of possessesCratoxylum Cochinchinense

antiplasmodial activity


Cynaroside (Luteolin 7-glucoside Luteolin 7-O-β-D-glucoside) Cat No HY-N0540

Cynaroside is a flavone a flavonoid-like chemicalcompound It is a 7-O-glucoside of luteolin


DaidzeinCat No HY-N0019

Daidzein is a soy isoflavone which acts as a activatorPPAR

Purity 9966Clinical Data Phase 4Size 10 mM times 1 mL 500 mg 1 g 5 g 10 g

Daidzin (Daidzoside NPI-031D Daidzein 7-O-glucoside) Cat No HY-N0018

Daidzin is an isoflavone that has anti-oxidantanti-carcinogenic and anti-atheroscleroticactivities directly inhibits mitochondrialaldehyde dehydrogenase 2 (IC50 = 80 nM) and is aneffective anti-dipsotropic isoflavone

Purity 9953Clinical Data Phase 1Size 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg

Deguelin ((-)-Deguelin (-)-cis-Deguelin) Cat No HY-13425

Deguelin a naturally occurring rotenoid is apotent inhibitorPI3KAKT


Demethylwedelolactone Sulfate (Demethylwedelolactone 3-sulfate) Cat No HY-N2028A

Demethylwedelolactone Sulfate(Demethylwedelolactone 3-sulfate) is a coumestanisolated from Eclipta prostrata L


DichotomitinCat No HY-N2120

Dichotomitin is an isoflavonoid isolated from therhizomes of (L) DCBelamcanda chinensis



DidyminCat No HY-N2068

Didymin a dietary flavonoid glycoside from citrusfruits possesses antioxidant properties Didymininduces by inhibiting N-Myc andapoptosisupregulating RKIP in neuroblastoma


DihydroactinidiolideCat No HY-107805

Dihydroactinidiolide existing in plant leaves andfruits is a potent plant growth inhibitor aregulator of gene expression and is responsiblefor photo acclimation in Arabidopsis


DihydrokaempferolCat No HY-N2897

Dihydrokaempferol is isolated from Bauhinia (Benth) Dihydrokaempferol induceschampionii

and inhibits Bcl-2 and Bcl-xL expressionapoptosisDihydrokaempferol is a good candidate for newantiarthritic drugs


Dihydromyricetin (Ampelopsin Ampeloptin) Cat No HY-N0112

Dihydromyricetin is a potent inhibitor with an of 48 μM on IC50 dihydropyrimidinase

Dihydromyricetin can activate autophagy throughinhibiting signaling DihydromyricetinmTORsuppresses the formation of mTOR complexes( )mTORC1 2


DiosmetinCat No HY-N0125

Diosmetin is a natural flavonoid which inhibitshuman enzyme activity with an of 40 μMCYP1A IC50

in HepG2 cell


DiosMetin 7-O-β-D-GlucuronideCat No HY-N6879

DiosMetin 7-O-β-D-Glucuronide is an antioxidantconstituent in the fruits of Luffa cylindrical


Diosmetin-7-O-β-D-glucopyranosideCat No HY-N0713

Diosmetin-7-O-β-D-glucopyranoside is a naturalproduct isolated from the flowers of

with antioxidantChrysanthemum morifoliumactivity


DiosminCat No HY-N0178

Diosmin is a flavonoid found in a variety ofcitrus fruits and also an agonist of the aryl

( )hydrocarbon receptor AhR

Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 50 mg

DracorhodinCat No HY-N4081

Dracorhodin the main component in sanguisdraconis is a flavylium compound belonging to theanthocyanin family Dracorhodin can inducevasodilatation


EchinatinCat No HY-N0269

Echinatin is a chalcone isolated from the Chineseherbal medicine with hepatoprotective andGancaoanti-inflammatory effects Echinatin may undergoan electron transfer (ET) and a proton transfer(PT) to cause the antioxidant action in aqueoussolution



EngeletinCat No HY-N0436

Engeletin is a flavanonol glycoside isolated from inhibits hymenaea martiana NF-κB

signaling-pathway activation and possessesanti-inflammatory analgesic diuresisdetumescence and antibiosis effects


EnocyaninCat No HY-114336

Enocyanin is an anthocyanin extracted from grapesEnocyanin shows inhibitory effect on the leucineaminopeptidase acid phosphatase γ-glutamyltranspeptidase and esterase activity

Purity gt98Clinical Data No Development ReportedSize 10 mg(10 mg times mL in DMSO) 100 mg

Epimedin ACat No HY-N0257

Epimedin A is a natural compound extracted fromHerba Epimedii


Epimedin A1 (Hexandraside F) Cat No HY-N0258

Epimedin A1 is a flavonoid extracted from HerbaEpimedii which is one of commonly used Chinesemedicines


Epimedin BCat No HY-N0259

Epimedin B a component extracted from EpimediiFolium is reported to have antiosteoporoticactivity


Epimedoside ACat No HY-N2626

Epimedoside A is a flavonoid isolated from theroots of Epimedoside AEpimedium wushanenseexhibits significant antioxidant activity invitro


Epitheaflagallin 3-O-gallateCat No HY-N4298

Epitheaflagallin 3-O-gallate is a minor polyphenolin black tea


Epmedin C (Epimedin-C Baohuoside-VI) Cat No HY-N0260

Epmedin C a natural product has estrogen-likeeffects for ovariectomized mice


EriocitrinCat No HY-N0636

Eriocitrin is a flavonoid isolated from lemonwhich is a strong antioxidant agent Eriocitrincould inhibit the proliferation of hepatocellularcarcinoma cell lines by arresting cell cycle in Sphase through up-regulation of p53 cyclin Acyclin D3 and CDK6


Eriodictyol (Huazhongilexone) Cat No HY-N0637

Eriodictyol is a flavonoid isolated from theChinese herb with antioxidant andanti-inflammatory activity Eriodictyol induces

signaling pathwayNrf2



EriosematinCat No HY-N4313

Eriosematin is a compound from the roots of with antiproliferativeFlemingia philippinensis

activity and -inducing propertyapoptosis


EupatilinCat No HY-N0783

Eupatilin a lipophilic flavonoid isolated from species is a agonist andArtemisia PPARα

possesses anti-apoptotic anti-oxidative andanti-inflammatory activities


EupatorinCat No HY-N2374

Eupatorin a naturally occurring flavone arrestscells at the G2-M phase of the cell cycle andinduces apoptotic cell death involving activationof multiple caspases mitochondrial release ofcytochrome c and poly(ADP-ribose) polymerasecleavage


FarrerolCat No HY-N0344

Farrerol is a bioactive constituent ofRhododendron with broad activities such asanti-oxidative anti-inflammatory anti-tumorneuroprotective and hepatoprotective effects


FisetinCat No HY-N0182

Fisetin is a natural flavonol found in many fruitsand vegetables with various benefits such asantioxidant anticancer neuroprotection effects

Purity 9802Clinical Data Phase 2Size 10 mM times 1 mL 100 mg 500 mg 1 g

Flavokawain CCat No HY-N2445

Flavokawain C is a natural chalcone found in Kavaroot Flavokawain C exerts cytotoxicity againsthuman cancer cell lines with an IC of 1275 μM50

for HCT 116 cells


Flemiphilippinin ACat No HY-N4316

Flemiphilippinin A is a prenylated isoflavoneisolated from Flemingia philippinensis


Formononetin (Biochanin B Flavosil Formononetol) Cat No HY-N0183

Formononetin (Formononetol Flavosil) is abioactive component extracted from the red cloverinhibits the proliferation of DU-145PC-3 cells ina dose-dependent manner


Galangin (Norizalpinin 357-Trihydroxyflavone) Cat No HY-N0382

Galangin (Norizalpinin)is an agonistantagonist ofthe arylhydrocarbon receptor Galangin(Norizalpinin) also shows inhibition of CYP1A1activity


GarcinolCat No HY-107569

Garcinol a polyisoprenylated benzophenoneharvested from exertsGarcinia indicaanti-cholinesterase properties towards acetyl

and cholinesterase (AChE) butyrylcholinesterase with s of 066 microM and 739 microM(BChE) IC50

respectively



Gardenin BCat No HY-N6037

Gardenin B is a flavonoid isolated from Baccharis Gardenin B induces cell death in humanscandens

leukemia cells involves multiple caspases


Gastrodenol (Bismuth tripotassium dicitrate Bismuth subcitrate) Cat No HY-B0796

Gastrodenol(Bismuth tripotassium dicitrateDe-Noltab)is a mineral that is used in treatingulcers and upset stomach

Purity gt950Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g

Genistein (NPI 031L) Cat No HY-14596

Genistein a soy isoflavone is a multiple tyrosine (eg ) inhibitor which acts as akinases EGFR

chemotherapeutic agent against different types ofcancer mainly by altering the cellapoptosiscycle and angiogenesis and inhibiting metastasis


Genistin (Genistine Genistoside Genistein

7-O-β-D-glucopyranoside) Cat No HY-N0595

Genistin is the major isoflavonoid of soybeans andsoy products


Genkwanin (Puddumetin) Cat No HY-N0731

Genkwanin is a major non-glycosylated flavonoidwith anti-flammatory activities


GinkgetinCat No HY-N0889

Ginkgetin is a natural biflavonoid isolated fromleaves of Ginkgo biloba L effects ofanti-inflammation and anticancer have beenreported


GlabranineCat No HY-N3942

Glabranine an flavonoid is isolated fromTephrosia sp exerts a inhibitory effect in vitroon the dengue virus Glabranine forms interactionwith the soluble ectodomain of DENV type 2( ) E proteinDENV2


GlabreneCat No HY-N3943

Glabrene an isoflavene derived from licoriceroot shows estrogen-like activity Glabrene is a

inhibitor with an of 35 μMtyrosinase IC50


GlabridinCat No HY-N0393

Glabridin is a natural isoflavan from Glycyrrhiza binds to and activates with anglabra PPARγ

of 6115 nMEC50


GlabrolCat No HY-N4193

Glabrol (Compound 1) One isoprenyl flavonoid wasisolated from ethanol extract of licorice rootsis a potent and non-competitive Acyl-coenzyme

inhibitorA cholesterol acyltransferase (ACAT)with an value of 246 μM for rat liverIC50

microsomal ACAT activity



GlabroneCat No HY-N4194

Glabrone is an isoflavone isolated from Glycyrrhiza roots Glabrone exhibits anti-influenzaglabra

activity and significant PPAR-γ ligand-bindingactivity


Glycitein (Glycetein) Cat No HY-N0016

Glycitein is a soybean (yellow cultivar)isoflavonoid used in combination with otherisoflavonoids such as genistein and daidzein tostudy apoptosis and anti-oxidation processes


Glycitin (Glycitein 7-O-β-glucoside) Cat No HY-N0012

Glycitin is a natural isoflavone isolated fromlegumes promotes the proliferation of bone marrowstromal cells and osteoblasts and suppresses boneturnover


GlycyrosideCat No HY-N6984

Glycyroside is a isoflavone diglycoside isolatedfrom P C LiGlycyrrhiza eurycarpa


GlycyrrhisoflavoneCat No HY-N3962

Glycyrrhisoflavone an active prenylflavonoidmainly derived from the extract of the roots of

Fisch GlycyrrhisoflavoneGlycyrrhiza uralensisinhibits α-glucosidase


Graveobioside ACat No HY-N4318

Graveobioside A is an anthoxanthin glycoside


GrosvenorineCat No HY-N3031

Grosvenorine is the major flavonoid compound ofthe fruits of GrosvenorineSiraitia grosvenoriiexhibits good antibacterial and antioxidantactivities


GuaijaverinCat No HY-N2224

Guaijaverin is a inhibitor with an ofurease IC50

120 μM Guaijaverin shows antioxidant andanti- activitiesStreptococcus mutans


HamaudolCat No HY-N6891

Hamaudol is a chromone isolated from Saposhnikovia Hamaudol shows significant inhibitorydivaricata

activity on and cyclooxygenase (COX)-1 COX-2activities with values of 030 057 mMIC50

respectively and has potent analgesia andanti-inflammary effects


HerbacetinCat No HY-N0240

Herbacetin is a natural flavonoid from flaxseedexerts various pharmacological activitiesincluding antioxidant anti-inflammatory andanticancer effects



HesperetinCat No HY-N0168

Hesperetin is a natural flavanone and acts as apotent and broad-spectrum inhibitor against human



Hesperidin (Hesperetin 7-rutinoside) Cat No HY-15337

Hesperidin (HP) is a bioflavonoid that plays arole in plant defense and is abundant in citrusspecies such as grapefruit lemon and orange

Purity 9700Clinical Data Phase 3Size 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg 1 g

Hexamethylquercetagetin (Hexa-O-methylquercetagetin

Quercetagetin hexamethyl ether hellip) Cat No HY-N4308

Hexamethylquercetagetin is a polymethoxylatedflavone in peels of citrus cultivars


HinokiflavoneCat No HY-N2360

Hinokiflavone is a novel modulator of pre-mRNAsplicing activity in vitro and in celluloHinokiflavone blocks splicing of pre-mRNAsubstrates by inhibiting spliceosome assemblyspecifically preventing B complex formation


Hispidulin (Dinatin) Cat No HY-N1950

Hispidulin is a natural flavone with a broadspectrum of biological activities Hispidulin is aPim-1 inhibitor with an of 271 μMIC50


HomomangiferinCat No HY-111811

Homomangiferin isolated from the leaves of M L is mangiferin monomethyl etherindica

Homomangiferin has important medicinal propertiesand is widely used to relieve many symptoms forexample coughing and asthma


HomoplantagininCat No HY-N1949

Homoplantaginin is a flavonoid from a traditionalChinese medicine withSalvia plebeiaantiinflammatory and antioxidant propertiesHomoplantaginin could inhibit and mRNATNF-α IL-6expression and phosphorylationIKKβ NF-κB


Hydroxygenkwanin (7-O-Methylluteolin) Cat No HY-N1438

Hydroxygenkwanin (7-O-Methylluteolin) a naturalflavonoid compound is one of the main componentsof Lilac Daphne Hydroxygenkwanin has anti-oxidantability anti-glioma ability and anticancereffect


Hydroxysafflor yellow A (Safflomin A HSYA) Cat No HY-N0567

Hydroxysafflor yellow A is a flavonoid derived andisolated from traditional Chinese medicineCarthamus tinctorius L possesses anti-tumoractivity


HyperosideCat No HY-N0452

Hyperoside a natural flavonoid isolated from possesses antifungalCamptotheca acuminate

anti-inflammatory anti-viral anti-oxidative andanti-apoptotic activities



Icariin (Ieariline) Cat No HY-N0014

Icariin is a flavonol glycoside Icariin inhibits and activities with s of 432 nMPDE5 PDE4 IC50

and 7350 μM respectively Icariin also is a activatorPPARα


Icariside I (Icarisid I) Cat No HY-N1939

Icariside I is a metabolite of Icarlin whichcould regulate bone remodeling and is recognizedas an effective agent for the treatment ofosteoporosis


Icaritin (Anhydroicaritin) Cat No HY-N0678

Icaritin (Anhydroicaritin) is a prenylflavonoidderivative from and potentlyEpimedium Genusisinhibits proliferation of K562 cells ( of 8IC50

microM) and primary CML cells ( of 134 microM forIC50

CML-CP and 18 microM for CML-BC)


IKarisoside A (Icarisoside-A Baohuoside II) Cat No HY-N0875

IKarisoside A(Icarisoside-A) is a natural compoundisolated from Epimedium koreanum (Berberidaceae)has anti-inflammatory properties


Ikarisoside F (Ikarisoside-F Icarisoside-F) Cat No HY-N0861

Ikarisoside F is a flavonol glycoside fromVancouveria hexandra could bind to AdoHcyhydrolase


IpriflavoneCat No HY-N0094

Ipriflavone is a synthetic isoflavone derivativeused to suppress bone resorption

Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g

IridinCat No HY-N3011

Iridin is an isoflavone isolated from Irismilesii


IrigeninCat No HY-N2587

Irigenin is a is a lead compound and mediates itsanti-metastatic effect by specifically andselectively blocking and integrinsα9β1 α4β1binding sites on C-C loop of Extra Domain A (EDA)Irigenin shows anti-cancer properties


IrisflorentinCat No HY-N0268

Irisflorentin a naturally occurring isoflavoneis an abundant active constituent in RhizomaBelamcandae Irisflorentin markedly reduces thetranscriptional and translational levels ofinducible nitric oxide synthase (iNOS) as well asthe production of NO Anti-inflammatory activity


Iristectorin ACat No HY-N6820

Iristectorin A a natural product from Iris has anti-cancer activities in breasttectorum

cancer



Iristectorin BCat No HY-N6819

Iristectorin B is an isoflavone from Iris has anti-cancer activities in breasttectorum

cancer


Isobavachalcone (Corylifolinin Isobacachalcone) Cat No HY-13065

Isobavachalcone (Corylifolinin) is derived from and is a potent inhibitorPsoralea corylifolia Linn

of signaling pathway which induces apoptosisAktin human cancer cells (Inhibits OVCAR-8 cellgrowth with an value of 792 μM)IC50


IsoginkgetinCat No HY-N2117

Isoginkgetin is a MMP-9 inhibitor also a Pre-mRNASplicing Inhibitor with IC 50 of 30 uM target MMP-9 Pre-mRNA Splicing IC 50 30 u M (Pre-mRNASplicing) In vitro Isoginkgetin inhibits HT1080tumor cell invasion substantially


IsoglycycoumarinCat No HY-N6989

Isoglycycoumarin is a flavonoid isolated from theroots of Isoglycycoumarin isGlycyrrhiza uralensisa highly selective probe for human cytochrome

P450 2A6 (CYP2A6)


Isoliquiritigenin (GU17 ISL Isoliquiritigen) Cat No HY-N0102

Isoliquiritigenin is an anti-tumor flavonoid fromthe root of which inhibits Glycyrrhiza glabra aldose

with an of 320 nMreductase IC50


IsoliquiritinCat No HY-N0765

Isoliquiritin isolated from Licorice Rootinhibits angiogenesis and tube formationIsoliquiritin also exhibits antidepressant-likeeffects and antifungal activity


IsomangiferinCat No HY-N0772

Isomangiferin a natural product is reported tohave antiviral activity


Isoorientin (Homoorientin) Cat No HY-N0767

Isoorientin is a potent inhibitor of withCOX-2an value of 39 μMIC50


Isoquercitrin (Isoquercitroside) Cat No HY-N0768

Isoquercitrin (Isoquercitroside) is an effectiveantioxidant and an eosinophilic inflammationsuppressor


Isorhamnetin (3-Methylquercetin) Cat No HY-N0776

Isorhamnetin is a flavonoid compound extractedfrom the Chinese herb LHippophae rhamnoidesIsorhamnetin suppresses skin cancer through directinhibition of and MEK1 PI3K



Isorhamnetin 3-O-galactoside (Cacticin) Cat No HY-N2082

Isorhamnetin 3-O-galactoside (Cacticin) aflavonoid glycoside isolated from Artemisia

Thunberg which ameliorates CCl4-inducedcapillarishepatic damage by enhancing the anti-oxidativedefense system and reducing the inflammatorysignaling pathways


Isorhamnetin-3-O-neohespeidosideCat No HY-N0778

Isorhamnetin-3-O-neohespeidoside is a flavonoidisolated from Pollen typhae


IsorhoifolinCat No HY-N3460

Isorhoifolin is a flavonoid glycoside from leaves Isorhoifolin displaysperiploca nigrescens

an anti-leakage effect


IsosakuranetinCat No HY-N2131

Isosakuranetin is a flavanone flavonoid which canbe found in the fruit of Citrus bergamia


IsosakuraninCat No HY-N4296

Isosakuranin is a natural product derived from thefruits of Paliurus ramosissimus


IsoschaftosideCat No HY-N1458

Isoschaftoside a C-glycosylflavonoid from root exudate canDesmodium uncinatum

inhibit growth of germinated S hermonthicaradicles


Isosilybin (Isosilybinin) Cat No HY-N0779

Isosilybin (Isosilybinin) is a flavonoid from milkthistle inhibits induction with an CYP3A4 IC50

of 74 μM


Isosilybin ACat No HY-N7043

Isosilybin A a flavonolignan isolated fromsilymarin has anti-prostate cancer (PCA)activity

Purity gt990Clinical DataSize 10 mM times 1 mL 1 mg 5 mg

Isosilybin BCat No HY-N7045

Isosilybin B a flavonolignan isolated fromsilymarin has anti-prostate cancer (PCA) activityvia inhibiting proliferation and inducing G1 phasearrest and Isosilybin B causes apoptosis androgen

degradationreceptor (AR)


IsosinensetinCat No HY-N1941

Isosinensetin a polymethoxylated flavoneextracted from pericarpium citri reticulataeviride exhibits inhibition on P-glycoprotein

in MDR1-MDCKII cells(P-gp)



Isotanshinone ICat No HY-N6649

Isotanshinone I has inhibitory activity against and formation of with ofα-glucosidase AGE IC s50

113 0432 μM for α-glucosidase and AGErespectively


IsoviolanthinCat No HY-N6896

Isoviolanthin is a flavonoid glycoside extractedfrom the leaves of Dendrobium officinale


Isovitexin (Saponaretin Homovitexin) Cat No HY-N0773

Isovitexin is a flavonoid isolated from rice hullsof possesses anti-inflammatory andOryza sativaanti-oxidant activities Isovitexin acts like a

inhibitor and inhibits the activation ofJNK12NF-κB


JaceosidinCat No HY-N0831

Jaceosidin is a flavonoid isolated from induces apoptosis in cancerArtemisia vestita

cells activates and down-regulates Mcl-1 andBaxc-FLIP expression


JuglaninCat No HY-N3442

Juglanin is a activatorJNK


Kaempferide (Kaempferol 4-O-methyl ether) Cat No HY-15449

Kaempferide is an O-methylated flavonol a type ofchemical compound It can be found in Kaempferiagalanga (aromatic ginger)


Kaempferitrin (Lespedin Lespenephryl) Cat No HY-N0628

Kaempferitrin is a natural flavonoid possessesantinociceptive anti-inflammatory anti-diabeticantitumoral and chemopreventive effects andactivates signaling pathwayinsulin


Kaempferol (Kempferol Robigenin) Cat No HY-14590

Kaempferol inhibits estrogen receptor αexpression in breast cancer cells and inducesapoptosis in glioblastoma cells and lung cancercells by activation of MEK-MAPK


Kaempferol 374-trimethyl etherCat No HY-N3434

Kaempferol 374-trimethyl ether is a flavonolaglycone isolated from the leaves of Siparuna

has antioxidant activitygigantotepala


Kaempferol 3-O-arabinosideCat No HY-N3433

Kaempferol 3-O-arabinoside is an antioxidantflavonoids isolated from ethyl acetate fraction(EAF) obtained from the leaves of Nectandra hihuaKaempferol 3-O-arabinoside has good antioxidantcapacity



Kaempferol 3-O-gentiobiosideCat No HY-N1510

Kaempferol 3-O-gentiobioside is a flavonoidisolated from leaves with antidiabeticC alataactivity Kaempferol 3-O-gentiobioside possessesactivity against α-glucosidase and displayscarbohydrate enzyme inhibitory effect with an IC50

of 500 microM


Kaempferol-3-O-(6-trans-p-coumaroyl-2-glucosyl)rhamnosi

de Cat No HY-N6965

Kaempferol-3-O-(6-trans-p-coumaroyl-2-glucosyl)rhamnoside is a natural antioxidant from herbalmedicines


Kaempferol-3-O-glucorhamnosideCat No HY-N0208

Kaempferol-3-O-glucorhamnoside a flavonoidderived from plant TurczThesium chinenseinhibits inflammatory responses via MAPK and NF-κBpathways in vitro and in vivo


Kaempferol-7-O-β-D-glucopyranosideCat No HY-N0627

Kaempferol-7-O-β-D-glucopyranoside is a flavonoidisolated from Mill flowersMalus pumilahas antioxidative anti-inflammatory andprocoagulant activitives


KakkalideCat No HY-N4244

Kakkalide is an isoflavone derived from theflowers of Kakkalide amelioratesPueraria lobataendothelial insulin resistance by suppressingreactive oxygen species (ROS)-associatedinflammation


Kanzonol CCat No HY-N4181

Kanzonol C a flavonoid isolated from the twigs of (Moraceae) has potential to treatDorstenia barteri

bacterial and fungal infections


KurarinoneCat No HY-N2279

Kurarinone a flavanoid derived from shrub Sophora inhibits the process of experimentalflavescens

autoimmune encephalomyelitis via blocking Th1 andTh17 cell differentiation


Kuromanin chloride (Chrysontemin Cyanidin 3-O-glucoside chloride) Cat No HY-N0640

Kuromanin (chloride) extracted from mulberryleaves has been shown to improve blood glucoseconcentrations and lipid homeostasis and to reduceobesity

Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg

Kushenol A (Leachianone E) Cat No HY-N2278

Kushenol A is isolated from the root of Sophora a non-competitive inhibitorflavescent tyrosinase

with and values of 11 μM and 04 μMIC50 Ki

respectively Kushenol A is a flavonoidantioxidant has inhibitory effects on

and alpha-glucosidase beta-amylase


Kushenol ECat No HY-N2463

Kushenol E is a class of flavonoids isolated from and is a non-competitiveSophora flavescens

inhibitorindoleamine 23-dioxygenase 1 (IDO1)with an of 77microM and a of 95microM hasIC50 Ki

anti-tumor activity



Kuwanon ACat No HY-N2300

Kuwanon A is a flavone derivative isolated fromthe root barks of the mulberry tree (Morus alba

) inhibits nitric oxide production with an L IC50

of 105 μM


Kuwanon ECat No HY-N3514

Kuwanon E is a flavonoid isolated from Morus cytotoxic to human monocytic leukemic cellalba

lines and reduces the level of IL-1β


Kuwanon GCat No HY-N4247

Kuwanon G is a flavonoid isolated from Morus acts as a antagonistalba bombesin receptor

with potential antimicrobial activity


Kuwanon HCat No HY-N2600

Kuwanon H is a flavonoid isolated from Morus which acts as a potent non-peptidebombycis

antagonist Kuwanon Hbombesin receptorselectively inhibits binding of gastrin releasingpeptide CRP to with a GRP-preferring recepotr Ki

value of 290 nM in cells


Leachianone ACat No HY-N2281

Leachianone A isolated from hasRadix Sophoraeanti-malarial anti-inflammatory and cytotoxicpotent Leachianone A induces apoptosis involved

both extrinsic and intrinsic pathways


Licochalcone A (Licochalcone-A) Cat No HY-N0372

Licochalcone A a flavonoid isolated from thefamous Chinese medicinal herb Glycyrrhizauralensis Fisch presents obvious anti-cancereffects The IC50 value is 097 μM for UGT1A1

Purity 9972Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg 100 mg

Licochalcone CCat No HY-N0374

Licochalcone C could inhibit withα-glucosidase of lt100 nM and 9243 μM for α-glucosidaseIC s50

and protein tyrosine phosphatase 1B (PTP1B)respectively


Licochalcone DCat No HY-N4187

Licochalcone D a flavonoid compound mainlyexisting in the root of is aGlycyrrhiza inflatepotent inhibitor of NF-kappaB (NF-κB) p65Licochalcone D possesses antioxidantanti-inflammatory anti-cancer properties


Licochalcone ECat No HY-N4182

Licochalcone E a flavonoid compound isolated from inhibits NF-κB and AP-1Glycyrrhiza inflate

transcriptional activity through the inhibition of and activationAKT MAPK


Licoflavone ACat No HY-N4185

Licoflavone A is a flavonoid isolated from theroots of inhibits proteinGlycyrrhiza uralensistyrosine phosphatase-1B ( ) with an ofPTP1B IC50

545 μM



Licoflavone BCat No HY-N4184

Licoflavone B is a flavonoid isolated from inhibits Glycyrrhiza inflata S mansoni ATPase

( 2378 microM) and ( 3150 microM)IC50 ADPase IC50

activity Anti-schistosomiasis activity


Licoflavone CCat No HY-N4183

Licoflavone C is a prenyl-flavone extracted from reduces the genotoxicity ofGenista ephedroides

cancer drugs in human peripheral lymphocytes


LicoflavonolCat No HY-N6583

Licoflavonol a minor flavone from the roots of is an inhibitor of theGlycyrrhiza uralensis

type III secretion system (T3SS)Salmonella


Licoisoflavone ACat No HY-N3389

Licoisoflavone A an isoflavone mainly derivedfrom Fisch Licoisoflavone AGlycyrrhiza uralensisinhibits lipid peroxidation with an IC of 72 μM50


Licoisoflavone BCat No HY-N3388

Licoisoflavone B an isoflavone mainly derivedfrom Fisch Licoisoflavone BGlycyrrhiza uralensisinhibits lipid peroxidation with an IC of 27 μM50


LicoriconeCat No HY-N3386

Licoricone is an flavonoid extracted fromlicorice exhibits anti-helicobacter pyloriactivity against the CLAR and AMOX-resistantstrain as well as four CLAR (AMOX)-sensitivestrains


Licorisoflavan ICat No HY-N5157

Licorisoflavan I an isoflavone mainly derivedfrom FischGlycyrrhiza uralensis


Liguiritigenin-7-O-D-apiosyl-4-O-D-glucosideCat No HY-N2624

Liguiritigenin-7-O-D-apiosyl-4-O-D-glucoside is aflavanone glycoside isolated from Glycyrrhizia

inflate


Ligustroflavone (Nuezhenoside) Cat No HY-N0546

Ligustroflavone extracted from Ligustrum is a potential candidate aslucidum

antagonistcalcium-sensing receptor (CaSR)Ligustroflavone exhibits protective effectsagainst diabetic osteoporosis in mice


Liquiritigenin (47-Dihydroxyflavanone) Cat No HY-N0377

Liquiritigenin a flavanone isolated from is a highly selectiveGlycyrrhiza uralensis

estrogen receptor β ( ) agonist with an ERβ EC50

of 365 nM for activation of the ERE tk-Luc



Liquiritigenin-7-O-β-D-glucopyranosyl-(1rarr2)-β-D-apiofuranosi

de Cat No HY-N6986

Liquiritigenin-7-O-β-D-glucopyranosyl-(12)-β-D-apiofuranoside (Liquiritigenin-7-apiosylglucoside)is a flavonoid isolated from the roots of

has weaker cytotoxicity againstGlycyrrhizaseveral tumor cells and normal cells


LiquiritinCat No HY-N0376

Liquiritin a flavonoid isolated from Glycyrrhizais a potent and competitive inhibitor withAKR1C1

s of 062 μM 061 μM and 372μM for AKR1C1IC50

AKR1C2 and AKR1C3 respectively Liquiritinefficiently inhibits progesterone metabolismmediated by AKR1C1 in vivo


Loureirin ACat No HY-N1505

Loureirin A is a flavonoid extracted from DragonsBlood can inhibit phosphorylation and hasAktantiplatelet activity


Loureirin BCat No HY-N1504

Loureirin B a flavonoid extracted from Dracaena is an inhibitor of plasminogencochinchinensis

activator inhibitor-1 with an IC of(PAI-1) 50

2610μM Loureirin B also inhibits theKATP

phosphorylation of and and hasERK JNKanti-diabetic activity


Luteolin (Luteoline Luteolol Digitoflavone) Cat No HY-N0162

Luteolin (Luteolol) is a flavanoid withanti-inflammatory anti-cancer propertiesincluding the induction of and cell cycleapoptosisarrest and the inhibition of metastasis andangiogenesis in several cancer cell linesincluding human non-small lung cancer cells


Luteolin 7-diglucuronideCat No HY-N7269

Luteolin 7-diglucuronide is the major flavonoidisolated from and Aloysia triphylla Verbena

officinalis


Luteolin 7-O-glucuronide (Luteolin 7-glucuronide) Cat No HY-N1463

Luteolin 7-O-glucuronide could inhibit MatrixMetalloproteinases activities with (MMP) IC s50

of 1763 799 1142 1285 003 μM for MMP-1MMP-3 MMP-8 MMP-9 MMP-13 respectively


Luteolin-3-O-beta-D-glucuronideCat No HY-N4099

Luteolin-3-O-beta-D-glucuronide is a luteolinglucosiduronic acid consisting of luteolin havinga beta-D-glucosiduronic acid residue attached atthe 3-position


Luteolin-7-rutinosideCat No HY-N6647

Luteolin-7-rutinoside has both anti-arthritic andantifungal activities can result in a combinationtherapy for the treatment of fungal arthritis dueto infectionC albicans


Luteolinidin chlorideCat No HY-129997

Luteolinidin is a natural deoxyanthocyanidinisolated from mosses and ferns Luteolinidin is apotent CD38 inhibitor which can protect the heartagainst IR injury with preservation of eNOSfunction and prevention of endothelial dysfunctionin vivo



LysionotinCat No HY-107222

Lysionotin is a flavonoid isolated from fewflower herbs Lysionotinlysionotusefficiently inhibit (a pore-formingα-toxinprotein) expression and shows significantprotection against in vitro and inS aureusvivo


MangiferinCat No HY-N0290

Mangiferin is a activator MangiferinNrf2suppresses nuclear translocation of the NF-κBsubunits and p65 p50


MauritianinCat No HY-N5038

Mauritianin is a kaempferol glycoside isolatedfrom the flowers and leaves of Acalypha indicaMauritianin is a inhibitortopoisomerase I


Methylnissolin-3-O-glucosideCat No HY-N2473

Methylnissolin-3-O-glucoside(Methylnissolin-3-O-β-D-glucoside) is a flavonoidfrom the roots of withAstragalus membranaceusanti-inflammatory effects


Methylophiopogonanone BCat No HY-N2438

Methylophiopogonanone B homoisoflavonoid isextracted from the root of Ophiopogon japonicasshows high antioxidant ability


Methylophiopogonone ACat No HY-N2441

Methylophiopogonone A a homoisoflavonoid isolatedfrom the tuberous roots of Ophiopogon japonicasshows anti-inflammatory activity


Miquelianin (Quercetin 3-O-glucuronide Quercetin 3-glucuronide) Cat No HY-13930

Miquelianin (Quercetin 3-O-glucuronide) is ametabolite of quercetin and a type of naturalflavonoid


Mirificin (Puerarin apioside) Cat No HY-N2134

Mirificin (Puerarin apioside) is a isoflavone in Radix Mirificin inhibitsPuerariae Lobatae

with an of 1266 μMtyrosinase (TYR) IC50


Morusin (Mulberrochromene) Cat No HY-N0622

Morusin is a prenylated flavonoid isolated from with various biological activitiesM australis

such as antitumor antioxidant and anti-bacteriaproperty Morusin could inhibit and NF-κB STAT3activity


Mulberrin (Kuwanon C) Cat No HY-N3513

Mulberrin is a strong inhibitor of organicanion-transporting polypeptide 2B1(OATP2B1)-mediated estrone-3-sulfate (E3S) uptakewith an value being 18plusmn15 μMIC50



Myricetin (Cannabiscetin) Cat No HY-15097

Myricetin is a common plant-derived flavonoid witha wide range of activities including stronganti-oxidant anticancer antidiabetic andanti-inflammatory activities


NaringeninCat No HY-N0100

Naringenin is the predominant flavanone ingrapefruit displays strong anti-inflammatory andantioxidant activities

Purity 9872Clinical Data Phase 1Size 10 mM times 1 mL 100 mg 500 mg 1 g 5 g

Naringin (Naringoside) Cat No HY-N0153

Naringin is a major flavanone glycoside obtainedfrom tomatoes grapefruits and many other citrusfruits Naringin exhibits biological propertiessuch as antioxidant anti-inflammatory andantiapoptotic activities


Naringin Dihydrochalcone (Naringin DC) Cat No HY-N0119

Naringin Dihydrochalcone is an artificialsweetener derived from naringin Naringin is amajor flavanone glycoside obtained from tomatoesgrapefruits and many other citrus fruits


NeobavaisoflavoneCat No HY-N0720

Neobavaisoflavone an isoflavone isolated fromPsoralea corylifolia has strikinganti-inflammatory and anti-cancer effects


NeodiosminCat No HY-N4122

Neodiosmin is a flavone glycoside isolated fromthe leaves of Citrus aurantium


Neohesperidin (Hesperetin 7-O-neohesperidoside) Cat No HY-N0101

Neohesperidin is a flavonoid compound found inhigh amounts in Poncirus trifoliata withanti-oxidant and anti-inflammatory effects

Purity 9674Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg 500 mg 1 g 5 g

Neohesperidin dihydrochalcone (Neohesperidin DC NHDC) Cat No HY-N0154

Neohesperidin dihydrochalcone is a syntheticglycoside chalcone is added to various foods andbeverages as a low caloric artificial sweetener


NeoisoliquiritinCat No HY-N2122

Neoisoliquiritin is a bioactive component isolatedfrom Glycyrrhiza uralensis


NeoliquiritinCat No HY-N2123

Neoliquiritin is isolated from Glycyrrhiza uralensiswith an anti-inflammatory activity



Nepetin (6-Methoxyluteolin) Cat No HY-N2572

Nepetin (6-Methoxyluteolin) is a natural flavonoidisolated from HBKEupatorium ballotaefoliumwith potent anti-inflammatory activities Nepetininhibits and secretion with IL-6 IL-8 MCP-1 IC50

values of 443 μM 342 μM and 417 μMrespectively in ARPE-19 cells


NevadensinCat No HY-N1377

Nevadensin is a naturally occurring selectiveinhibitor of human carboxylesterase 1 with(hCE1)an of 264 μM Nevadensin has a variety ofIC50

pharmacological effects such as anti-mycobacteriumtuberculosis activities antitussiveanti-inflammatory and anti-hypertensive


NicotiflorinCat No HY-N1475

Nicotiflorin is a flavonoid glycoside extractedfrom a traditional Chinese medicine Flos

Nicotiflorin shows potentCarthami activity and neuroprotection effectsantiglycation


NobiletinCat No HY-N0155

Nobiletin is a poly-methoxylated flavone from thecitrus peel that improves memory loss Nobiletinis a retinoid acid receptor-related orphan

agonistreceptors (RORs)


NoricaritinCat No HY-N1413

Noricaritin is a flavonoid sourced from roots of MaximEpimedium brevicornu


ObacunoneCat No HY-N0428

Obacunone isolated from seeds of Marsh Whitegrapefruit exhibits anti-tumor activity by theinduction of apoptosis


OkaninCat No HY-N6673

Okanin effective constituent of the flower tea attenuates LPS-inducedCoreopsis tinctoria

microglial activation through inhibition of the signaling pathwaysTLR4 NF-κB


Ononin (Ononoside Formononetin 7-O-β-D-glucopyranoside) Cat No HY-N0270

Ononin is an isoflavonoid is an additional growthinhibitor in soils associated with the weedPluchea lanceolata


Orientin-2-O-p-trans-coumarateCat No HY-N5047

Orientin-2-O-p-trans-coumarate is a flavonoidfound in with potentTrigonella foenum-graecumantioxidant activity


Oroxin ACat No HY-N2025

Oroxin A is the major component of anethanol-water (L) KurzOroxylum indicum(Bignoniaceae) seed extract (OISE) activatesperoxisome proliferator-activated receptor γ( ) by docking into the PPARγ proteinPPARγligand-binding domain



Oroxin BCat No HY-N1435

Oroxin B (OB) is a flavonoid isolated fromtraditional Chinese herbal medicine Oroxylum

(L) Ventindicum


Oroxylin A (Baicalein 6-methyl ether 6-Methoxybaicalein) Cat No HY-N0560

Oroxylin A is a natural active flavonoid withstrong anticancer effects IC50 value Target Invitro Oroxylin A suppressed the MDM2-mediateddegradation of p53 via downregulating MDM2transcription in wt-p53 cancer cells


Osajin (CID 95168 NSC 21565) Cat No HY-N3125

Osajin is the major bioactive isoflavone present inthe fruit of withMaclura pomiferaantitumor antioxidant and anti-inflammatoryactivities


Phlorizin (Floridzin NSC 2833) Cat No HY-N0143

Phlorizin is a non-selective inhibitor withSGLTs of 300 and 39 nM for and Ki hSGLT1 hSGLT2

respectively Phlorizin is also a Na K -ATPase+ +

inhibitor

Purity 9533Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g

Pinocembrin ((+)-Pinocoembrin Dihydrochrysin Galangin flavanone) Cat No HY-N0575

Pinocembrin ((+)-Pinocoembrin) is a flavonoidfound in propolis acts as a competitive inhibitorof and is an effectivehistidine decarboxylaseanti-allergic agent with antioxidantantimicrobial and anti-inflammatory properties


Pinocembrin 7-O-[3-O-galloyl-46-hexahydroxydiphenoyl]

-β-D-glucoside Cat No HY-N5084

Pinocembrin 7-O-[3-O-galloyl-46-hexahydroxydiphenoyl]-β-D-glucoside is a flavanone compound


Podocarpusflavone ACat No HY-N2198

Podocarpusflavone A is a DNA topoisomerase Iinhibitor have moderated anti-proliferativeactivity induce cell apoptosis in MCF-7 isdeveloping anti-tumor drugs target DNAtopoisomerase I In vitro podocarpusflavone-A showsignificant inhibitions against DLD KBhellip


Pomiferin (NSC 5113) Cat No HY-N4315

Pomiferin (NSC 5113) a flavonoid from the fruitsof acts as an potentialMaclura pomiferainhibitor of with an of 105 μM andHDAC IC50

also potently inhibits ( 62 microM)mTOR IC50


ProanthocyanidinsCat No HY-N0794

Proanthocyanidins are a class of polyphenolic thatare widely distributed in higher plants consistedof an electrophilic flavanyl unitProanthocyanidins can be used as antioxidant andanti-cancers agent


Procyanidin A1 (Proanthocyanidin A1) Cat No HY-N2344

Procyanidin A1 (Proanthocyanidin A1) is aprocyanidin dimer which inhibits degranulationdownstream of protein kinase C activation or Ca2+

influx from an internal store in RBL-213 cellsProcyanidin A1 has antiallergic effects



Procyanidin A2Cat No HY-N2343

Procyanidin A2 is a flavonoid found in cranberriesand lingonberries with anti-cancer antioxidantantimicrobial and anti-inflammation activity


Procyanidin B1Cat No HY-N0795

Procyanidin B1 is a polyphenolic flavonoidisolated from commonly eaten fruits binds to

complex and has anti-inflammatoryTLR4MD-2activity


Procyanidin B2 (Proanthocyanidin B2) Cat No HY-N0796

Procyanidin B2 is a natural flavonoid withanti-cancer antioxidant activities



Procyanidin B3 is a natural product acts as aspecific inhibitor binds to the other siteHATof instead of the active site selectivelyp300inhibits p300-mediated androgen receptoracetylation Procyanidin B3 has no effect on HDACor HMT (histone methyltransferase)


Procyanidol B4 ((-)-Procyanidin B4) Cat No HY-107208

Procyanidol B4 ((-)-Procyanidin B4) is a flavanolisolated from Anti-inflammatoryLitchi chinensisproperties


Pterosin BCat No HY-N1570

Pterosin B a indanone found in bracken fern( ) is an inhibitor ofPteridium aquilinum

signaling Pterosin Bsalt-inducible kinase 3 (Sik3)prevents chondrocyte hypertrophy andosteoarthritis in mice by inhibiting Sik3

Purity gt98Clinical Data No Development ReportedSize 10 mM times 1ml 1 mg 5 mg 10 mg

PuerarinCat No HY-N0145

Puerarin an isoflavone extracted from Radix is a receptor antagonistpuerariae 5-HT2C


Quercetagetin (6-Hydroxyquercetin) Cat No HY-N4149

Quercetagetin (6-Hydroxyquercetin) is the majorflavonoid isolated from ( )Citrus unshiu C unshiupeel Quercetagetin is a moderately potent andselective cell-permeable kinasepim-1inhibitor ( 034 μM) Anti-inflammatory andIC50

anticancer properties


QuercetinCat No HY-18085

Quercetin a natural flavonoid is a stimulator ofrecombinant and also a inhibitor withSIRT1 PI3K

of 24plusmn06 μM 30plusmn00 μM and 54plusmn03 μM forIC50

PI3K γ PI3K δ and PI3K β respectively

Purity gt980Clinical Data Phase 4Size 10 mM times 1 mL 500 mg 1 g 5 g

Quercetin 3-gentiobiosideCat No HY-N4089

Quercetin 3-gentiobioside is isolated from A and formation inhibitoriwayomogi AR AGE

demonstrates biological activities against Aldosereductase (AR) and the formation of advancedglycation endproducts (AGEs)



Quercetin-3-O-β-D-glucose-7-O-β-D-gentiobiosiden (Quercetin-3-O-beta-D-glucose-7-O-beta-D-gentiobioside) Cat No HY-N1968

Quercetin-3-O-β-D-glucose-7-O-β-D-gentiobiosidenis a flavonoid from Quercetin


Quercitrin (Quercetin 3-rhamnoside) Cat No HY-N0418

Quercitrin is a natural compound found in Tartarybuckwheat with a potential anti-inflammationeffect that is used to treat heart and vascularconditions


Reynoutrin (Quercetin-3-D-xyloside Reinutrin) Cat No HY-N1354

Reynoutrin (Quercetin-3-D-xyloside) is a flavonoidfrom with antioxidantPsidium cattleianumand radical-scavenging activity


RhamnetinCat No HY-N7036

Rhamnetin is a quercetin derivative found in inhibits secretoryCoriandrum sativum

with antioxidant andphospholipase A2anti-inflammatory activity


RhamnocitrinCat No HY-N1353

Rhamnocitrin is a flavonoid isolated fromastragalus complanatus R Br (Sha-yuan-zi)Rhamnocitrin is a scavenger of DPPH with an IC50

of 2838 mM Rhamnocitrin has anti-oxidantanti-inflammatory and an-tiatherosclerosisactivity


RhodiolinCat No HY-N6841

Rhodiolin is a flavonoid isolated from Rhodiolafastigita


Rocaglamide (Rocaglamide A Roc-A) Cat No HY-19356

Rocaglamide (Rocaglamide A) is isolated from thegenus and can be used to treat coughsAglaiainjuries asthma and inflammatory skin diseasesRocaglamide is a potent inhibitor of NF-κBactivation in T-cells

Purity 9934Clinical Data No Development ReportedSize 10 mM times 1 mL 200 μg 1 mg 5 mg 10 mg 25 mg

Rutin (Rutoside Quercetin 3-O-rutinoside) Cat No HY-N0148

Rutin a naturally occurring flavonoid glycosidehas antioxidant anti-inflammatory anti-allergicanti-angiogenic and antiviral properties


Safflor yellow ACat No HY-N7274

Safflor yellow A a flavonoid extracted from L is a water-solubleCarthamus tinctorius

monomer of safflor yellow Safflor yellow Aprotects rat cardiomyocytes againstanoxiareoxygenation (AR) injury via inhibitingcellular oxidative stress and apoptosis


Safflower red (Carthamin) Cat No HY-N6646

Safflower red a red pigment is isolated fromsafflower and used as a natural antioxidant in thefood cosmetics and clothing industries



Safflower yellowCat No HY-N0938

Safflower yellow is extracted from the flowers ofthe plant safflower ( ) andCarthamus tinctoriusas the traditional Chinese medicine it has beenextensively used for the treatment of cardiocerebrovascular diseases


Sagittatoside A (Icariin-A) Cat No HY-N0873

Sagittatoside A is a natural compound isolatedfrom traditional Chinese herb Yinyanghuo (HerbaEpimdii)


Sagittatoside BCat No HY-N0874

Sagittatoside B is a natural compound isolatedfrom traditional Chinese herb Yinyanghuo (HerbaEpimdii)


SakuranetinCat No HY-N3006

Sakuranetin is a rice flavonoid phytoalexin showsstrong antifungal activity Sakuranetin hasanti-inflammatory and antioxidative activitiesSakuranetin ameliorates LPS-induced acute lunginjury


Sanggenon CCat No HY-N0617

Sanggenon C is a flavanone Diels-Alder adductcompound which is isolated from the root bark of

Sanggenon C exerts protectiveMorus cathayanaeffects against cardiac hypertrophy and fibrosisvia suppression of the pathwaycalcineurinNFAT2


Sanggenon DCat No HY-N0618

Sanggenon D is a Diels-Alder-type adduct fromChinese crude drug root bark of Morus cathayanaSanggenon D possesses antioxidant and inhibitsPancreatic lipase (PL) with the an IC of 077 μM50


SchaftosideCat No HY-N0703

Schaftoside is a flavonoid found in a variety ofChinese herbal medicines such as Eleusine indicaSchaftoside inhibits the expression of TLR4 andMyd88 Schaftoside also decreases Drp1 expressionand phosphorylation and reduces mitochondrialfission

Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 20 mg

Scutellarein (6-Hydroxyapigenin 4567-Tetrahydroxyflavone) Cat No HY-N0752

Scutellarin a main active ingredient extractedfrom Erigeron breviscapus (Vant) Hand-Mazz hasbeen wildly used to treat acute cerebralinfarction and paralysis induced bycerebrovascular diseases


Scutellarein tetramethyl ether (4567-Tetramethoxyflavone) Cat No HY-N4314

Scutellarein tetramethyl ether(4567-Tetramethoxyflavone) is a bioactivecomponent of Siam weed extract Scutellareintetramethyl ether (4567-Tetramethoxyflavone)exhibits anti-inflammatory activity through NF-κBpathway


ScutellarinCat No HY-N0751

Scutellarin an active flavone isolated fromScutellaria baicalensis can down-regulates the

signaling in HCC cells andSTAT3GirdinAktinhibits RANKL-mediated MAPK and NF-κBsignaling pathway in osteoclasts



Scutellarin methyl esterCat No HY-N6925

Scutellarin methyl ester is a constituent ofBreviscapine which is a crude extract of severalflavonoids of Erigeron breviscapus


Semilicoisoflavone BCat No HY-N1280

Semilicoisoflavone B an isoflavone mainlyderived from FischGlycyrrhiza uralensisSemilicoisoflavone B reduces ( )amyloid β Aβsecretion by inhibiting β-secretase-1 (BACE1)expression and activity


Shogaol ([6]-Shogaol 6-Shogaol) Cat No HY-14616

Shogaol (-Shogaol) an active compound isolatedfrom Ginger ( Rosc) exhibits aZingiber officinalevariety of biological activities includinganticancer anti-inflammation and anti-oxidation


Silibinin (Silybin Silibinin A Silymarin I) Cat No HY-13748

Silibinin (Silybin) an effective anti-cancer andchemopreventive agent has been shown to exertmultiple effects on cancer cells includinginhibition of both cell proliferation andmigration

Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg

SilychristinCat No HY-N0647

Silychristin is an abundant flavonolignan presentin the fruits of withSilybum marianumantioxidant properties Silychristin is a potentinhibitor of the thyroid hormone transporter

and elicits a strong inhibition of T3MCT8uptake with an IC of 110 nM50


SilydianinCat No HY-N0646

Silydianin is an active constituent of Silybium with exhibit anti-collagenasemarianum

antitumor and anti-elastase activities Silydianinis a natural protein tyrosine phosphatase 1B

with an of 1738μM(PTP1B) IC50


Sinensetin (Pedalitin permethyl ether) Cat No HY-N0297

Sinensetin is a methylated flavone found incertain citrus fruits pocess potentantiangiogenesis and anti-inflammatory sinensetinenhances adipogenesis and lipolysis


SophoflavescenolCat No HY-N2284

Sophoflavescenol is a prenylated flavonol whichshows great inhibitory activity with of 0013IC50

μM against and alsoPhosphodiesterase 5 (PDE5)inhibits RLAR HRAR AGE BACE1 AChE and BChEwith IC s of 030 microM 017 microM 1789 microgmL 109850

microM 837 microM and 821 microM respectively


SophoricosideCat No HY-N0423

Sophoricoside is an isoflavone glycoside isolatedfrom Sophora japonica and has anti-inflammatoryanti-cancer and immunosuppressive effects


SotetsuflavoneCat No HY-N2199

Sotetsuflavone is a potent inhibitor of DENV-NS5RdRp (Dengue virus NS5 RNA-dependent RNApolymerase) with an IC50 of 016 uM is the mostactive compound of this series



SwertiajaponinCat No HY-N2204

Swertiajaponin is a tyrosinase inhibitor formsmultiple hydrogen bonds and hydrophobicinteractions with the binding pocket oftyrosinase with an of 4347 μMIC50


SwertisinCat No HY-N2189

Swertisin a C-glucosylflavone isolated from is known to have antidiabeticSwertia japonica

anti-inflammatory and antioxidant effectsSwertisin is an antagonistadenosine A1 receptor


SyringaldehydeCat No HY-N1390

Syringaldehyde is a polyphenolic compoundbelonging to the group of flavonoids and is foundin different plant species like Manihot

and esculenta Magnolia officinalisSyringaldehyde moderately inhibits activityCOX-2with an of 35 μgmLIC50


Tangeretin (Tangeritin NSC53909 NSC618905) Cat No HY-N0133

Tangeretin (Tangeritin) a flavonoid from citrusfruit peels has been proven to play an importantrole in anti-inflammatory responses andneuroprotective effects in several disease modelsand is a inhibitorNotch-1


Taxifolin ((+)-Dihydroquercetin (+)-Taxifolin) Cat No HY-N0136

Taxifolin ((+)-Dihydroquercetin) exhibitsimportant anti- activity Taxifolintyrosinaseexhibits significant inhibitory activity against

with an value of 1933 μMcollagenase IC50


Tectochrysin (Techtochrysin NSC 80687) Cat No HY-14592

Tectochrysin (Techtochrysin) is one of the majorflavonoids of Miquel TectochrysinAlpinia oxyphylla(Techtochrysin) inhibits activity of NF-κB


TectorigeninCat No HY-N0792

Tectorigenin is a plant isoflavonoid originallyisolated from the dried flower of Pueraria

Benththomsonii


Tectorigenin 7-O-Xylosyl GlucosideCat No HY-N4172

Tectorigenin 7-O-Xylosyl Glucoside is aglycosidic isoflavone isolated from Pueraria

flowerthomsonii


TheaflavinCat No HY-N0243

Theaflavin is a suitable natural inhibitor againstinfluenza A ( ) neuraminidaseH1N1


Theaflavin 33-digallate (TF3) Cat No HY-N1992

Theaflavin 33-digallate (TF3) the typicalpigment in black tea is a good antitumor agent



Theaflavin-3-gallateCat No HY-N0244

Theaflavin-3-gallate a black tea theaflavinmonomer is regarded as the biologically importantactive component of black tea and provides healthbenefits Theaflavin-3-gallate acts asprooxidants and induces oxidative stress in thecarcinoma cells



Theaflavin-3-gallate a black tea theaflavinmonomer is regarded as the biologically importantactive component of black tea and provides healthbenefits Theaflavin-3-gallate acts as prooxidantsand induces oxidative stress in the carcinomacells


ToringinCat No HY-N4192

Toringin a bioflavonoid is isolated from thebark of Docyniopsis tschonoski Toringinprogressively decreases not only the cis-effect ofthe expanded CTG repeats but cytotoxicity as wellExposure to isosakuranetin Toringin rescues PC12neuronal cells


Toxicarol isoflavoneCat No HY-N1135

Toxicarol isoflavone is an isoflavone extractedfrom Millettia brandisiana


TribulosideCat No HY-N2443

Tribuloside is isolated fromPotentilla Tribuloside exhibitsmultifid

activity against theanti-mycobacterialnon-pathogenic Mycobacterium species with aminimum inhibitory concentration (MIC) 50 mgmL


TricinCat No HY-N1127

Tricin is a natural flavonoid present in largeamounts in rice bran Tricin can inhibit human

replication bycytomegalovirus (HCMV)inhibiting CDK9


TrifolirhizinCat No HY-N0616

Trifolirhizin is a pterocarpan flavonoid isolatedfrom the roots of TrifolirhizinSophora flavescenspossesses potent inhibitory activitytyrosinasewith an of 506 μM Trifolirhizin exhibitsIC50

potential anti-inflammatory and anticanceractivities


Troxerutin (Trihydroxyethylrutin) Cat No HY-N0139

Troxerutin also known as vitamin P4 is atri-hydroxyethylated derivative of naturalbioflavonoid rutins which can inhibit theproduction of ( ) andreactive oxygen species ROSdepress ER stress-mediated activationNOD

Purity 9805Clinical Data Phase 4Size 10 mM times 1 mL 100 mg 5 g

TyphaneosideCat No HY-N0712

Typhaneoside extracted from LTypha angustifoliaTyphaneoside can inhibit the excessive autophagyof hypoxiareoxygenation cells and increase thephosphorylation of Akt and mTOR


Usaramine N-oxideCat No HY-N6827

Usaramine N-oxide a flavonoid isolated from possesses anti-inflammatoryCrotalaria pallida

activities



Vicenin 2Cat No HY-N2165

Vicenin 2 is an angiotensin-converting enzyme( ) inhibitor ( =4383 μM) from the aerialACE IC50

parts of Desmodium styracifolium






ViolanthinCat No HY-N6895

Violanthin is isolated from the aerial parts of has potent antioxidant andPiper bavinum

antibacterial activities Violanthin inhibitsacetylcholinesterase ( ) with an value ofAChE IC50

7980 μM


VitexinCat No HY-N0013

Vitexin is a c-glycosylated flavone and is foundin various medicinal plants species such as Ficus

and Vitexin has a widedeltoid Spirodela polyrhizarange of pharmacological effects includinganti-oxidant anti-cancer anti-inflammatoryanti-hyperalgesic and neuroprotective effects


Vitexin 4-glucoside (4-O-Glucosylvitexin) Cat No HY-N4085

Vitexin 4-glucoside is a leaf flavonoididentified from Briza stricta


Vitexin arginineCat No HY-N7044

Vitexin arginine is a c-glycosylated flavone andis found in various medicinal plants species suchas and Ficus deltoid Spirodela polyrhiza


Vitexin-2-O-rhamnosideCat No HY-N0534

Vitexin-2-O-rhamnoside a main flavonoid glycosideof the leaves of BgeCratagus pinnatifidacontributes to the protection againstH O -mediated oxidative stress damage and has2 2

potential to treat cardiovascular system diseases


Warangalone (Scandenolone) Cat No HY-N1074

Warangalone is an anti-malarial compound which caninhibit the growth of both strains of parasite

(chloroquine sensitive) and (chloroquine3D7 K1resistant) with s of 48 μgmL and 37 μgmLIC50

respectively


WogoninCat No HY-N0400

Wogonin is a naturally occurring mono-flavonoidcan inhibit the activity of and andCDK8 Wntexhibits anti-inflammatory and anti-tumor effects


WogonosideCat No HY-N0399

Wogonoside a flavonoid glycoside isolated fromHuangqin possesses anti-inflammatory effectsWogonoside induces autophagy in breast cancercells by regulating MAPK-mTOR pathway



XanthohumolCat No HY-N1067

Xanthohumol is one of the principal flavonoidsisolated from hops the inhibitor ofdiacylglycerol acetyltransferase ( ) DGAT COX-1and COX-2 and shows anti-cancer andanti-angiogenic activities


Xanthohumol DCat No HY-N1066

Xanthohumol D isolated from hops is an inhibitorof with the valuequinone reductase-2 (QR-2) IC50

of 110 μM and binds to the active site of QR-2Xanthohumol D shows antiproliferative activity onhuman cancer cell lines in vitro


[6]-Gingerol ((S)-(+)-[6]Gingerol 6-Gingerol) Cat No HY-14615

-Gingerol is an active compound isolated fromGinger ( ) exhibits aZingiber officinale Roscvariety of biological activities includinganticancer anti-inflammation and anti-oxidation



Flavonoids Inhibitors amp Modulators

(+)-Catechin hydrateCat No HY-N0355

(+)-Catechin hydrate inhibits cyclooxygenase-1( ) with an of 14 μMCOX-1 IC50

Purity 9922Clinical Data Phase 4Size 100 mg

(+)-GallocatechinCat No HY-N0521A

(+)-Gallocatechin is a polyphenol compound fromgreen tea possesses anticancer activity


(+)-KavainCat No HY-B1671

(+)-Kavain a main kavalactone extracted from Piper has anticonvulsive propertiesmethysticum

attenuating vascular smooth muscle contractionthrough interactions with voltage-dependent Na+

and Ca channels2+


(+)-MedicarpinCat No HY-N6052

(+)-Medicarpin a pterocarpan is a type ofisoflavonoid isolated from several medicinal plantspecies with various biological effects including

andSophora japonica Zollernia paraensis Platymiscium yucatamun Machaerium

helliparistulatum


(-)-ButinCat No HY-N6020

(-)-Butin is the S enantiomer of Butin Butin is amajor biologically active flavonoid isolated fromthe heartwood of with strongDalbergia odoriferaantioxidant antiplatelet and anti-inflammatoryactivities


(-)-Catechin ((-)-Cianidanol (-)-Catechuic acid) Cat No HY-N0898A

(-)-Catechin isolated from green tea is anisomer of Catechin having a trans 2S3Rconfiguration at the chiral center Catechininhibits cyclooxygenase-1 (COX-1) with an IC of50

14 μM


(-)-Catechin gallate ((-)-Catechin 3-gallate (-)-Catechin 3-O-gallate) Cat No HY-N0356

(-)-Catechin gallate is a minor constituent ingreen tea catechins (-)-Catechin gallate inhibitsthe activity of and enzymesCOX-1 COX-2


(-)-Epicatechin ((-)-Epicatechol Epicatechin epi-Catechin) Cat No HY-N0001

(-)-Epicatechin inhibits cyclooxygenase-1 ( )COX-1with an of 32 μM (-)-Epicatechin inhibitsIC50

the IL-1β-induced expression of iNOS by blockingthe nuclear localization of the p65 subunit ofNF-κB


(-)-Epicatechin gallate (Epicatechin gallate ECG (-)-Epicatechin 3-O-gallate) Cat No HY-N0002

(-)-Epicatechin gallate (Epicatechin gallate)inhibits cyclooxygenase-1 ( ) with an ofCOX-1 IC50

75 μM


(-)-Epigallocatechin (Epigallocatechin EGC L-Epigallocatechin) Cat No HY-N0225

(-)-Epigallocatechin (EGC) is the most abundantflavonoid in green tea can bind to unfoldednative polypeptides and prevent conversion toamyloid fibrils





















of 454 nM



















































A virus











































lobata




of 101 μMIC50



























































COX-2







Kang-Jing
























pennatifolius




























































activity
















glandulosa






































































































































081 μM















































in HepG2 cell








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively






































of 454 nM



















































A virus











































lobata




of 101 μMIC50



























































COX-2







Kang-Jing
























pennatifolius




























































activity
















glandulosa






































































































































081 μM















































in HepG2 cell








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively






















































A virus











































lobata




of 101 μMIC50



























































COX-2







Kang-Jing
























pennatifolius




























































activity
















glandulosa






































































































































081 μM















































in HepG2 cell








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively






















A virus











































lobata




of 101 μMIC50



























































COX-2







Kang-Jing
























pennatifolius




























































activity
















glandulosa






































































































































081 μM















































in HepG2 cell








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively




























lobata




of 101 μMIC50



























































COX-2







Kang-Jing
























pennatifolius




























































activity
















glandulosa






































































































































081 μM















































in HepG2 cell








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively
























































COX-2







Kang-Jing
























pennatifolius




























































activity
















glandulosa






































































































































081 μM















































in HepG2 cell








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively






















COX-2







Kang-Jing
























pennatifolius




























































activity
















glandulosa






































































































































081 μM















































in HepG2 cell








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively













































































activity
















glandulosa






































































































































081 μM















































in HepG2 cell








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively










































activity
















glandulosa






































































































































081 μM















































in HepG2 cell








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively






















glandulosa






































































































































081 μM















































in HepG2 cell








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively
























































































































081 μM















































in HepG2 cell








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively






















































































081 μM















































in HepG2 cell








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively





















































081 μM















































in HepG2 cell








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively






















081 μM















































in HepG2 cell








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively




































in HepG2 cell








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively








































































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively







































for HCT 116 cells














respectively

































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively


















































of 6115 nMEC50















































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively



























































































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively























































































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively




















































cancer





cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively






















cancer











P450 2A6 (CYP2A6)













































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively











































of 74 μM



















































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively

























































of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively






















of 500 microM



de Cat No HY-N6965
































anti-tumor activity






of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively























of 105 μM



































545 μM






























inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively















































inflate













de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively





















de Cat No HY-N6986























officinalis






















































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively


























































































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively

























































































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively


























































(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively






















(L) Ventindicum











inhibitor



























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively























































































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively


















































































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively
















































































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively















































































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively











































Benththomsonii




flowerthomsonii









































activities














7980 μM



















respectively




















































activities














7980 μM



















respectively































7980 μM



















respectively































Documents

Flavonoids - MedchemExpress.com · pathway. Purity: >98% Clinical Data: Size: 1 mg, 5 mg 3'-Demethylnobiletin Cat. No.: HY-N4127 3'-Demethylnobiletin, a derivative of Nobiletin, is