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    Davao Medical School Foundation

    College of Medicine

    OBSTETRICS-GYNECOLOGY

    In Partial fulfillment of

    Requirements in OB-GYNE

    SUBMITTTED TO:

    DR. RUBY ROBISO

    SUBMITTED BY:

    CHERIE TAPIAXYLIA SAHARA E. TOCAO

    CHERIS VARGAS

    MAY 24,2013

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    GENERAL DATA

    This is a case of AB, a 28 year old primigravida , 38 1/7 weeks AOG who came in due

    to watery vaginal discharge.

    HISTORY OF PRESENT ILLNESS

    One day prior to admission , the patient noticed passage of clear, watery vaginal

    discharge,amounting to approximately 250 ml. She claimed to have a steady leakage of small

    amount of fluid but no consultation was done.Condition was not associated with vaginal

    pruritus, foul smelling discharge ,fever hypogastric or lumbosacral pain.

    Eighteen hours prior to admission ,patient still had vaginal discharge now associated

    with hypogastric pain radiating to her lumbosacral area occurring intermittently every 5 minutes

    lasting for approximately 1 minute . Patient tolerated her condition until 1 hour PTA, patient

    sought medical advice with her attending physician . Internal examination was done which

    revealed 5 cm cervical dilatation. She was advised for admission in this institution hence

    admitted.

    PAST MEDICAL HISTORY

    The patient is not a known diabetic , hypertensive or asthmatic with no previous history

    of any hospitalizations or surgical operations.She also has no known food or drug allergies.

    FAMILY HISTORY

    No heredofamilial diseases were noted on both sides.

    PERSONAL / SOCIAL HISTORY

    AB was born and raised in Davao City with a degree in Management Accountancy. She

    is currently employed . She got married last 2010.

    Her diet consists mostly of carbohydrates, proteins with moderate amounts of fat.She is

    not a smoker and only drinks alcoholic beverages occasionally.

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    GYNECOLOGIC HISTORY

    Patient had her menarche at 9 years old. Subsequent menstrual periods were regular

    lasting for 4 days moderate in quantity associated with occasional dysmenorrhea .Patient had

    her sexual debut at 18 years old with 1 sexual partner who eventually became her husband.

    OBSTETRIC HISTORY

    The patient is a primigravid. Her last menstrual period was last August 22, 2012 while

    her previous normal menstrual period was last July 2012. Her computed AOG is 38 weeks and 1

    day with her expected date of delivery falling on May 29, 2013. She had her first prenatal

    check-up at 12 weeks AOG, since then her succeeding prenatal check-ups have been regular

    with no unusualities noted. Until about 1 month PTA, when patient noted presence of dysuria ,

    fever and flank pains. She sought consultation with her attending physician and was diagnosed

    with urinary tract infection and was given ampicillin-Sulbactam, 750 mg tablet, 1 tab BID for 7

    days and was advised repeat urinalysis and follow-up checkup after 1 week, patient however,

    was non-compliant and did not return for her scheduled check-up.The patient does not have any

    history of previous contraceptive use. She had her pap smear last 2012 with normal findings as

    claimed.

    REVIEW OF SYSTEMS

    GENERAL (-) easy fatigability

    ENDOCRINE SYSTEM (-) thyroid problems, (-) neck surgery, (-) heat and cold intolerance

    SKIN (-) pruritus

    HEAD (-) dizziness, (-) headache

    EYE (-) pain, (-) excessive lacrimation

    EAR (-) tinnitus

    NOSE (-) persistent stuffiness, (-) nasal congestion, (-) postnasal drip

    MOUTH (-) bleeding gums, (-) dyspnea

    THROAT (-) odynophagia, (-) hoarseness

    NECK (-) neck surgery, (-) nuchal rigidity, (-) limited motion

    BREAST (-) breast pain, (-) abnormal discharge

    CARDIAC (-) nocturnal dyspnea, (-) murmurs

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    PERIPHERAL VASCULAR (-) claudication

    GASTROINTESTINAL (-) change in bowel habits

    PULMONARY (-) hemoptysis, (-) asthma

    GENITO-URINARY (+) dysuria, (+) urinary frequency

    HEMATOPOIETIC (-) easy brusing

    MUSCULAR (-) limited ROM

    NEUROLOGIC (-) change in orientation

    PHYSICAL EXAMINATION

    GENERAL

    The patient was examined conscious, coherent and responsive.

    VITAL SIGNS

    BP: 110/80 mmHg; PR: 91 bpm; RR: 20 bpm; temperature: 36.5 C

    Weight: 77kg ; Height: 52

    SHEENT:

    SKIN:

    Ifair complexion, no lesions/scars, no palmar erythema, nails without clubbing and cyanosis

    PAmoist and warm with good skin turgor. No palpable lesions, tenderness, lumps noted

    HEAD:

    Ihair is black in color, no lesions noted

    Anon-palpable lymph nodes

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    EYES:

    Ianicteric sclerae, pink palpebral conjunctivae

    EARS:

    Ino lumps, lesions noted

    PAnon-tender and mobile external ear

    NOSE:

    Isymmetric, no swelling noted, nasal septum at midline

    PAfrontal and maxillary sinuses are not tender

    MOUTH:

    Ino ulcers/lesions noted, tongue and vulva at midline, no tonsilar enlargement noted

    NECK:

    Isupple, no nuchal rigidity and gross thyromegaly, trachea at midline, no lesions noted

    BREAST:

    Ino redness/discharge noted

    PAno mass palpated, non-tender

    CHEST/LUNGS:

    Ino scars/ lesions noted

    PAnon-tender

    PEresonant

    Avesicular breath sounds in most areas without adventitious sounds

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    CARDIOVASCULAR:

    Iadynamic precordium

    PAsymmetric pulses, capillary refill time < 2 sec

    Ano murmurs noted. PMI at 5th ICS, left MCL

    ABDOMEN

    Ino lesions noted

    Anormoactive bowel sounds at 5 bowel sounds per minute

    PEdullness at RUQ, the rest is tympanic

    PAnon-tender

    Fundic Height32 cm

    Estimated Fetal Weight3100g

    Fetal backleft maternal side

    PELVIC EXAMINATION

    External genitalia grossly normal

    SPECULUM EXAMpooling of clear, watery discharge at the posterior vaginal fornix; cervix is

    smooth, pinkish in color with no lesions noted

    INTERNAL EXAM6cm cervical dilatation; 80% effacement; station -3; midposition; soft consistency;

    cephalic presentation; ruptured bag of water; Bishop score 9

    EXTREMITIES

    Ino lacerations, fissures noted

    PAwarm to touch, no edema noted

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    MUSCULOSKELETAL

    Inormal muscle strength of 5/5, normal ROM, no deformities, atrophy and swelling noted

    MENTAL STATUS

    The patient is appropriately dressed. She is in supine position and with good grooming. Cooperative with

    the interviewer. Mood is congruent with affect and appropriate. Thought process is coherent, no suicidal

    ideations or plans. Memory is intact to remote, recent and immediate recall.

    CRANIAL NERVES

    Iable to smell

    IIpupils equally round and reactive to light and accommodation

    IIIexhibit normal EOM

    IVable to move eyeballs obliquely

    Vblinks whenever sclera was lightly touched

    VIable to move eyeballs laterally

    VIIable to perform different facial expressions

    VIIIable to hear loud and soft spoken words

    IXable to elicit gag reflex

    Xable to swallow without difficulty

    XIable to shrug shoulders against resistance

    XIIable to protrude tongue at midline and move it side to side

    MOTOR:

    Muscle strength 5/5

    COORDINATION:

    Finger to nose test intact

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    SENSORY:

    Pinprick: intact

    Light touch, position and vibration: intact

    REFLEX:

    Negative primitive reflex

    Corneal reflex elicited

    ADMITTING IMPRESSION:

    G1P0 Pregnancy Uterine 38 1/7 weeks AOG, cephalic in active phase of labor , Premature

    Rupture of Membrane

    SALIENT FEATURES

    28 years old Married G1P0 38 1/7 weeks AOG Passage of watery vaginal discharge Dysuria and urinary frequency Fundic height of 32 cm Speculum examination:

    (+) pooling of clear watery discharge at the posterior vaginal fornicus. (+) fluid per cervical os

    Internal examination: 6 cm dilatation; 80% effacement; station -3; RBOW, clear; soft; midpostion (BS = 9)

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    DIFFERENTIAL DIAGNOSES

    Urinary Tract Infection-A urinary tract infection (UTI) is an infection that affects part of the urinary tract. When it

    affects the lower urinary tract it is known as a simplecystitis when it affects the upper urinary

    tract it is known as pyelonephritis .

    Ruled in due to: Passage of watery vaginal discharge Dysuria Urinary frequency

    Upon admission, we could not totally rule out UTI since further diagnostic work-up is needed such as

    urinalysis and the gold standard in diagnosing UTI , urine culture.

    BACTERIAL VAGINOSIS-is an abnormal vaginal condition that is characterized by vaginal discharge and results from an

    overgrowth of normal bacteria in the vagina.

    Ruled in due to the presence of: copius vaginal discharge

    We could not totally rule out this condition upon admission, however based on the character of the

    patients vaginal discharge this could be ruled out because the discharge in bacterial vaginosis is grayish

    in color and has an unpleasant, fishy odor.Ancillary procedure like gram stain is also needed.

    Leukorrhea of Pregnancy- Normal vaginal discharge during pregnancy called leukorrheais thin, white, milky and mildsmelling.

    Ruled in due to: Passage of watery vaginal discharge

    Ruled out based on the character of the vaginal discharge. Whitish, curd like discharge is common in

    leukorrhea.

    COURSE IN THE WARD

    Upon admission, patients vital signs were monitored. Patient was then hooked to a cardiotocogram (CTG), which revealed a Category 1 tracing Labor augmentation with Oxytocin was started.

    https://en.wikipedia.org/wiki/Infectionhttps://en.wikipedia.org/wiki/Urinary_systemhttps://en.wikipedia.org/wiki/Cystitishttps://en.wikipedia.org/wiki/Pyelonephritishttp://www.medicinenet.com/script/main/art.asp?articlekey=64117http://www.medicinenet.com/script/main/art.asp?articlekey=64117https://en.wikipedia.org/wiki/Pyelonephritishttps://en.wikipedia.org/wiki/Cystitishttps://en.wikipedia.org/wiki/Urinary_systemhttps://en.wikipedia.org/wiki/Infection
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    Progress of labor was monitored, during which time, patient was placed on anintermittent CTG monitoring.

    EFM

    FRIEDMANS CURVE

    Eleven hours after admission, patient delivered via Normal Spontaneous Delivery to alive baby boy in cephalic presentation with Apgar Score of 8 and 9, Ballard Score of 38

    weeks and birth weight of 3100g.

    Postpartum, patients condition was stable. No active bleeding was noted. Uterus waswell-contracted.

    Urinalysis was done and revealed the following results

    URINE FLOW CYTOMETRY

    WBC 19/UL

    RBC 133/UL

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    EPITHELIAL CELLS 26/UL

    CAST 0/UL

    BACTERIA 42/UL

    PHYSICAL EXAM

    COLOR YELLOW ORANGE

    CLARITY SLIGHTLY CLOUDY

    REACTION 5.0

    SPECIFIC GRAVITY 1.030

    CHEMICAL ANALYSIS

    GLUCOSE ++

    PROTEIN TRACE

    Patient was discharged on her 2nd day postpartum, with no unusualities.

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    CASE DISCUSSION

    Premature Rupture of Membranes

    This term defines spontaneous rupture of the fetal membranes before 37 completed weeks and before

    labor onset. Such rupture likely has a variety of causes, but many believe intrauterine infection to be a

    major predisposing event.

    Some studies suggest that the pathogenesis of preterm rupture relates to increased apoptosis of

    membranes cellular components and to increased levels of specific proteases in membranes and amniotic

    fluid. Much of the membranes tensile strength is provided by the extracellular matrix within the amnion.

    Interstitial amnionic collagens, primarily types I and III, are produced in mesenchymal cells and are the

    structural component most important for its strength.

    Clinical factors associated with PROM

    Low socioeconomic status, low body mass index, tobacco use, preterm labor history, UTI, vaginal

    bleeding at any time of pregnancy, cerclage, amniocentesis.

    DIAGNOSIS

    1. Vaginal Speculum Examthe speculum should be sterile as to not introduce microorganisms intothe vaginal vault

    - Examine the cervical os for dilatation, free flow of fluid, and pooling of fluid inposterior fornix. Visualization of fluid coming from the cervical os is diagnostic2. NItrazine paper testingvaginal pH is acidic, amniotic fluid pH is alkaline at 7.0-7.73. Fern slidemust allow slide to dry thoroughly prior to examination under microscope. Assess for

    arbonization of fluid. Cervical mucous has broad, ferning pattern that is different than the fern of

    amniotic fluid

    4. Ultrasonographyused to measure pockets of fluid and quantitate AFV to AFI.

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    MANAGEMENT

    GESTATIONAL AGE MANAGEMENT

    TERM (37 weeks) Proceed to delivery Group B Streptococcus prophylaxis recommended

    NEAR TERM (34-36 weeks) Same as abovePRETERM (32-33 weeks) Expectant management unless fetal pulmonary

    maturity is recommended Antibiotics recommended to prolong latency if no

    contraindications exist

    Costicosteroids recommended by some experts, butno consensus exists

    PRETERM (24-31 weeks) Expectant management Group B Streptococcus prophylaxis recommended Antibiotics recommended to prolong latency, if no

    contraindications exist

    Single course of corticosteroids recommended No consensus on use of tocolytics

    PRETERM (24 weeks) Patient counselling Expectant management/ induction of labor Group B Streptococcus prophylaxis not

    recommended

    Data incomplete on the use of antibiotics to prolonglatency

    Corticosteroids not recommended