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ACL graft comparison between patellar autograft, hamstring autograft and allographs By: David T. Payne IV

Final Grant Proposal Presentation 2

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Page 1: Final Grant Proposal Presentation 2

ACL graft comparison between patellar autograft, hamstring autograft and allographs

By: David T. Payne IV

Page 2: Final Grant Proposal Presentation 2

ACL • Anterior translation of the tibia, and

secondary to varus/valgus stress. • Age, knee joint laxity, activity level,

biomechanics, may lead to ACL tear• Most frequently repaired ligament in

the knee joint.

Page 3: Final Grant Proposal Presentation 2

Patellar Tendon Graft • Most widely used graft source and is

considered the gold standard.• Most popular choice due to the

strength, ease of harvest, quick healing, and good patient outcomes.

• Patella infera, patellar fractures, patellar tendon ruptures, tendonitis, anterior knee pain, synovitis

Page 4: Final Grant Proposal Presentation 2

Hamstrings Autograft• Semitendinosus muscle is most often

used.• Recreational athletes, low demand

patients, or youth• Should not be used in competitive

sprinters, those with generalized ligamentous laxity, or those with previous hamstring injury

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Allografts• Eliminates the donor morbidity and no

weakening of muscles • There is a shorter operating time, less

pain, smaller incisions, and better cosmetic result.

• Host immune response against donor tissue and an increase in cost.

Page 6: Final Grant Proposal Presentation 2

PurposePatients need to know the differences

between the choices for the repair graft.College athletes are highly active and

will want to know how each graft will handle long-term stress

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HypothesisResearch shows that patellar autografts

(BPTB) work best for highly active persons, including our college athletes

Comparing data groups such as success rate, rupture rate, pain levels, ect.

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Inclusion Criteria College aged athletesUndergone patellar autograft, allograft

or hamstring autograft to repair ACL injury

Within the past 3 years

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Exclusion Criteria College aged individuals that are not

athletes that have had one of the procedures.

Greater than 3 years since reconstruction

Any athlete with other surgeries

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Data Collection Initial selection Email contactQuestionnaire

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Data AnalysisANOVANO T-testPost Hoc Alpha level 0.05

Page 12: Final Grant Proposal Presentation 2

References 1. ElAttrache, S. N., Harner, D. C., Mizayan, R. (December 4, 2006) Surgical

Techniques in Sports Medicine. Lippincott Williams & Wilkins. 309-316. 

2. Shelbourne, K. D., Gray, T. (Dec, 1997). Anterior Cruciate Ligament Reconstruction with Autogenous Patellar Tendon Graft Followed by Accelerated Rehabilitation: A Two- to Nine-Year Followup. American Journal of Sports Medicine, 25(6): 786-95.

3. Marder, R. A., Raskind, J. R., Carroll, M. (Sept, 1991). Prospective evaluation of arthroscopically assisted anterior cruciate ligament reconstruction: Patellar tendon versus semitendinosus and gracilis tendons. American Journal of Sports Medicine, 19(5): 478-84.  

4. Rosenberg, T. D., Franklin, J. L., Baldwin, G. N., Nelson, K. A. (Sept-Oct, 1992) Extensor mechanism function after patellar tendon graft harvest for anterior cruciate ligament reconstruction. American Journal of Sports Medicine, 20(5): 519-526.

5. Shelbourne, K. D., Klootwyk, T. E., Wilckens, J. H., De Carlo, M. S. (Sept, 1995) Ligament Stability Two to Six Years After Anterior Cruciate Ligament Reconstruction with Autogenous Patellar Tendon Graft and Participation in Accelerated Rehabilitation Program. American Journal of Sports Medicine, 23(5): 575-579.

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6. Freedman, K. B., D’Amato, M. J., Nedeff, D. D., Kaz, A., Bach Jr, B. R. (Jan, 2003) Arthroscopic Anterior Cruciate Ligament Reconstruction: A Metaanalysis Comparing Patellar Tendon and Hamstring Tendon Autografts. American Journal of Sports Medicine, 31(1) 2-11.  

7. Sajovic, M., Strahovnik, A., Dernovsek, M. Z., Skaza, K. (June, 2011). Quality of Life and Clinical Outcome Comparison of Semitendinosus and Gracilis Tendon Versus Patellar Tendon Autografts for Anterior Cruciate Ligament Reconstruction: An 11 Year Follow-up of a Randomized Controlled Trial. American Journal of Sports Medicine, 39(10): 2161-2169 

8. Kurosaka, M., Yoshiya, S., Andrish, J. T. (June, 1987). A biomechanical comparison of different surgical techniques of graft fixation in anterior cruciate ligament reconstruction. American Journal of Sports Medicine, 15(3): 225-229.

9. Kraeutler, M. J., Bravman, J. T., McCarty, E. C. (Oct, 2013). Bone-Patellar Tendon-Bone Autograft Versus Allograft in Outcomes of Anterior Cruciate Ligament Reconstruction: A Meta-Analysis of 5182 Patients. American Journal of Sports Medicine, 41(10): 2439-2448. 

10. Yasuda, K., Kondo, E., Ichiyama, H., Kitamura, N., Tanebe, Y., Tohyama, H., et al. (Dec, 2004). Anatomic reconstruction of the anteromedial and pasteriolateral bundles of the anterior cruciate ligament using hamstring tendon grafts. Journal of Arthroscopic & Related Surgery, 20(10): 1015-1025.

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11. Yasuda, K., Kodo, E., Ichiyama, H., Tanebe, Y., Tohyama, H. (Mar, 2006). Clinical Evaluation of Anatomic Double-Bundle Anterior Cruciate Ligament Reconstruction Procedure using Hamstring Tendon Grafts: Comparisons Among 3 Different Procedures. Journal of Arthroscopy & Related Surgery, 22(3): 240-251.

12. Heijne, A., & Werner, S. (2010). A 2-year follow-up of rehabilitation after ACL reconstruction using patellar tendon or hamstring tendon grafts: a prospective randomised outcome study. Knee Surgery, Sports Traumatology, Arthroscopy, 18(6), 805-813. 

13. Xergia, S. A., McClelland, J. A., Kvist, J., Vasiliadis, H. S., & Georgoulis, A. D. (2011). The influence of graft choice on isokinetic muscle strength 4-24 months after anterior cruciate ligament reconstruction. Knee Surgery, Sports Traumatology, Arthroscopy, 19(5), 768-780.

14. Magnussen, R. A., Carey, J. L., & Spindler, K. P. (2011). Does autograft choice determine intermediate-term outcome of ACL reconstruction? Knee Surgery, Sports Traumatology, Arthroscopy,19(3), 462-472.

15. Landes, S., Nyland, J., Elmlinger, B., Tillett, E., & Caborn, D. (2010). Knee flexor strength after ACL reconstruction: comparison between hamstring autograft, tibialis anterior allograft, and non-injured controls. Knee Surgery, Sports Traumatology, Arthroscopy,18(3), 317-324.

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16. Zamarra, G., Fisher, M. B., Woo, S. Y., & Cerulli, G. (2010). Biomechanical evaluation of using one hamstrings tendon for ACL reconstruction: a human cadaveric study. Knee Surgery, Sports Traumatology, Arthroscopy, 18(1), 11-19.

17. Petersen, W., Zantop, T. (June, 2012). Return to play following ACL reconstruction: survey among experienced arthroscopic surgeons (AGA

instructors). Arthroscopy and Sports Medicine, 133: 969-977,  18. Sun, K., Tian, S., Zhang, J., Xia, C., Zhang, C., & Yu, T. (2009). Anterior

cruciate ligament reconstruction with BPTB autograft, irradiated versus non-irradiated allograft: a prospective randomized clinical study. Knee Surgery, Sports Traumatology, Arthroscopy, 17(5), 464-474.

19. Mehran, N., Skendzel, J. G., Lesniak, B. P., Bedi, A. (2013). Contemporary Graft Options in Anterior Cruciate Ligament Reconstruction. Operative Techniques in Sports Medicine, 21: 10-18.

20. Mall, N. A., Lee, A. S., Cole, B. J., Verma, N. N. (2013). The Functional and Surgical Anatomy of the Anterior Cruciate Ligament. Operative Techniques in Sports Medicine, 21: 2-9.

21. Magnussen, R., Spindler, K. P. (2013). Anterior Cruciate Ligament Reconstruction: Two Incision-Technique. Operative Techniques in Sports Medicine, 21: 34-39.

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22. Goldsmith, M. T., Jansson, K. S., Smith, S. D., Engebretson, L., LaPrade, R. F., Wijdicks, C. A. (2013). Biomechanical Comparison of Anatomic Single- and Double- Bundle Anterior Cruciate Ligament Reconstructions. American Journal of of Sports Medicine, 41(7): 1595-1604.  23. Viskontas, D. G., Giuffre, B. M., Duggal, N., Graham, D., Parker, D., Coolican, M. (2008). Bone Bruises Associated with ACL Rupture. American Journal of Sports Medicine, 36(5): 927-933.24. Mulford, J. S., Hutchinson, S. E., Hang, J. R. (Sept, 2012). Outcomes for primary anterior cruciate reconstruction with the quadriceps autograft: a systematic review. Knee Surgerons Sports Traumatol Arthroscopy, 21: 1882-1888. 25. Ghodadra, N. S, Mall, N. A., Grumet, R., Sherman, S. L, Kirk, S., Provencher, M. T., & Bach, B. R.(2012). Interval Arthrometric Comparison of Anterior Cruciate Ligament Reconstruction Using Bone-Patellar Tendon- Bone Autograft Versus Allograft: Do Grafts Attenuate Within the First Year Postoperatively? American Journal of Sports Medicine, 40(6), 1347-1354. 26. Mascarenhas, R., Tranovich, M., Kropf, E., Fu, F., & Harner, C. (2012). Bone-patellar tendon-bone autograft versus hamstring autograft anterior cruciate ligament reconstruction in the young athlete: a retrospective matched analysis with 2-10 year follow-up. Knee Surgery, Sports Traumatology, Arthroscopy, 20(8), 1520-1527.  27. Sun, K., Tian, S., Zhang, J., Xia, C., Zhang, C., & Yu, T. (2009). Anterior cruciate ligament reconstruction with BPTB autograft, irradiated versus non-irradiated allograft: a prospective randomized clinical study. Knee Surgery, Sports Traumatology, Arthroscopy, 17(5), 464-474.