Figure S1

A B

C

DEX - + + -RU - - + +

SDC1

Nucleus

Merged

C -9 -8 -7 -60.00

0.25

0.50

0.75

1.00

1.25

1.50

1.75

DEX [log M]

SD

C1

mR

NA

ex

pre

ss

ion

[A

U]

C DEX DEX + RU RU0.0

0.5

1.0

1.5

2.0

2.5

3.0

3.5

DEX - + + -RU - - + +

SD

C1

mR

NA

ex

pre

ss

ion

[A

U]