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A Holistic Approach to Healthcare and Health Systems
Infectious diseases and the global threat of antimicrobial resistance are affecting the human population
with devastating costs to society as the incidence of untreatable infectious diseases increases.
Taking a holistic health system approach based on actionable Big Data analytics, we can deliver
improved health outcomes, quality of life and productivity.
IBM Research is contributing to combat AMR and infectious diseases by harnessing Big Data research
and technologies to create a paradigm shift to address the root causes of AMR and infectious diseases.
www.zurich.ibm.com/science-posters/
References and links:
• www.youtube.com/watch?v=ABmIeWcmG3E
• M. Davis et al. “Spatio-temporal information and knowledge representation of disease incidence and
respective intervention strategies,” Studies in Health Technology and Informatics 205, 1173-1177, 2014
• www.zurich.ibm.com/~mre
Achieving the UN Millenium Development Goals
The Cognitive Health Care and Health System Hub represents a framework to build sustainable health
systems to reduce child mortality rates, improve maternal health and combat HIV/AIDS, malaria
and other diseases.
The framework comprises an interface for stakeholders, backed by a cognitive computing and advanced
analytics layer, and features an integrated data foundation.
An Interdisciplinary, Global Effort
This project brings together skills in microbiology, chemistry,
engineering and computer science from IBM Research – Africa,
Almaden, Australia, Yorktown Heights (USA) and Zurich.
We have also initiated a European consortium that will investigate
actionable Big Data (ABiD) to combat antimicrobial resistance.
Breaking the Disease Chain of Causation
Investigating the chain of causation with a holistic view allows us to understand
disease mechanisms, the spread of diseases and their impact on society.
This insight in turn creates opportunities to break the disease chain
through multiple and diverse actions, both on an individual
and a public-health level.
Cognitive Healthcare & Health Systems HubFighting Antimicrobial Resistance (AMR) and Infectious Diseases
Matthias Reumann, Kelly Wyres, Matthew Davis, Stefan von Cavallar, Martin J. Sepulveda, Meenal Pore, Priscilla Rogers
IBM Research GmbH
University of Zurich
CeMeT
Analytics Engines
Lund University
Aristotle University
of Thessaloniki
AgaplesionMaastricht University
Nutritional health promotion
and assessment
• Breast feeding
• Micronutrient supplements
• Malnourishment
HIV testing
Genetic status testing
• Sickle cell allele carrier
Emergency care
Access to therapy
Case management
Improve hygiene
Control exposure
• Siblings
• Daycare
Reservoir HostPortal of entryAgentMode of
transmission
Portal of exit
Human with
malaria
Mosquito bites
uninfected
human
Human
becomes
infected
Protozoa
multiplying in
mosquito
MosquitoMosquito bites
infected human
Distribute
insecticide-
treated nets
Insecticide
spraying
Monitor climate
• Mosquito development
Home materials
• Mosquito breeding
Understand species distribution
& resistance
Chain of causation – Malaria
Intervention opportunities
Understand
species
distribution &
resistance
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