The S/,(1I1! Journal (~{ Medicine

hl/, 31, ;'\/0. 2:fi/-96', JII1/(' 1990 (Review Article)

Fibricola seoulensis Seo, Rim and Lee, 1964 (Trematoda)and Fibricoliasis in Man

Byong-Seol Sea

Department (~{ girl/sitology, SI'()fI! National University C{lf/(I:I' (~r Medicine, Seoul 110-460, Korea

CONTENTS

INTRODUCTION······································ .. ··· 62

MORPHOLOGYGeneral Features of the Adult 62External Structure 64Internal Structure 67

Digestive Tract. Tribocytic Organ. Female Reproductive Organ.Male Reproducuve Organ. Excretory System

Description of Larval Flukes 69

Miracidium. Sporocyst and Cercaria. Metacercaria

LIFE CYCLEEmbryogenesis .. ·········· .. ········· .. ···.·.·· 71Experimental Infection of Snail with Miracidia 73Occurrence in Nature . 73

Experimental Infection of Tadpoles with Cercariae 73Experimental Infection of Rats & Mice with Metacercariae · .. · 74

CULTIVATION IN VITRO AND ON THE CHICK CHORIOALLANTOiS · ·.. · 74CLASSIFICATION

Systematic Position of the Genus Fibricola · · 76Classification of the Strigeids and Tribocytic Organ 77The Phylogeny of the Family Diplostomidae 78Description of the Species Reported 78

Differential Diagnosis: Key to the Species of the Genus Fibricola 83HUMAN FIBRICOLIASIS

Epidemiology 8:JPathology and Clinical Aspects 84

Experimental HistopathologyClinical Summary of the First Human Case

Diagnosis and Treatment 86Key to the Operculated Eggs 87

ACKNOWLEDGEMENT .. 88REFERENCES 89SYNOPSIS IN KOREAN 91