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Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Allen
Nicholson
anichol@te
mple.edu
CST Biology Analysis of a Gene-
regulatory
Ribonuclease Complex
Proteomic analyses of protein-protein interactions in the
bacterium Escherichia coli suggest that two ribonucleases,
RNase III and RNase II, as well as the protein YmdB,
function as a complex to process RNA molecules. We will
investigate how RNase III and RNase II may work in concert
to process RNA, and how YmdB regulates the action of
RNase III. These experiments will use purified recombinant
proteins and RNA substrates to examine the activity of the
protein complex and the individual proteins.
Main Interest in
biochemistry
and molecular
biology; strong
foundation of
basic
biochemical/bio
logical
concepts,
critical thinking
skills, attention
to detail,
willingness to
Biology,
Biochemistr
y - Biology
2112,
Genetics,
Chemistry
Allen
Nicholson
anichol@te
mple.edu
CST Biology Understanding
ribonuclease
mechanism and
function in gene
regulation
We apply biochemical and molecular genetic techniques to
probe the mechanism of ribonucleases and their function
in gene expression and RNA stability. Our primary system is
the bacterial cell, and we seek to understand how bacterial
cell motility, biofilm formation, and response to stress are
regulated by ribonucleases.
Main Strong
performance in
biology and
chemistry
courses
(including at
least one
semester of
organic
chemistry)
Biology and
Biochemistr
y, Biology,
Chemistry
majors
10/24/2019 1
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Amy
Freestone
amy.freest
one@templ
e.edu
CST Biology Biogeographic
variation in interaction
strength and invasions
at the ocean's
nearshore (BioVision).
Global patterns of biodiversity demonstrate that most of
the species on earth occur in the tropics, with strikingly
fewer species occurring in higher-latitude regions.
Biologists predict that this global pattern of species
diversity is likely shaped by ecological species interactions.
Yet few detailed experimental data exist that demonstrate
how species interactions influence ecological communities
from the tropics to the arctic. Therefore, a significant
opportunity exists to transform our understanding of how
these fundamental species interactions shape patterns of
biodiversity across the globe. Furthermore, these species
interactions have the strong potential to limit biological
invasions by non-native species, which are often
transported by human activities that breach historical
dispersal barriers, such as ocean basins and continents.
Biological invasions can cause undesired ecological and
economic effects and are considered one of the primary
drivers of global change. Through extensive field research
on marine ecosystems along the Pacific Coast of North and
Central America, from the tropics to the subarctic, this
project is elucidating ecological factors that shape global
patterns of diversity and limit biological invasions.
Main A strong
academic
record, a strong
interest in
ecology and
conservation,
and a desire to
apply these
interests in a
research
setting.
Relevant
coursework
(Principles of
Ecology, upper
level ecology
and/or
conservation
electives,
statistics, etc.) is
helpful but not
required.
Biology,
Environmen
tal Science
10/24/2019 2
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Ananias
Escalante
Ananias.Esc
alante@te
mple.edu
CST Biology Phylomedicine of
vector-borne
pathogens
It is increasingly evident that genomic information,
together with concepts from epidemiology and
evolutionary biology, allows for testing of hypotheses and
exploration of scenarios that otherwise could not be
investigated by traditional approaches. Our lab
characterizes the processes shaping the genetic variation of
vector-borne parasites and viruses. In particular, we utilize
genetic data to learn how pathogen populations respond
to the selective pressures exerted by the host immune
system or antimicrobial drugs. By comparing genetic data
derived from historical samples and/or comparing
pathogens genomes, we expect to provide information
regarding which types of parasite populations/dynamics
are most prone to the emergence of drug resistance or
how genes encoding antigens that are vaccine (or
diagnostic) targets change in time and space compromising
the efficacy of those public health interventions/tools. We
also utilize the parasite genetic information to ascertain
ongoing epidemiological processes such as outbreaks or
disease transmission patterns in space. Our approach
involves a suite of methods and models that include
population genetics/genomics analyses, phylogenetics, and
experimental work. The students’ main role will be to
assist in evolutionary genetic analyses. We are looking for 1
or 2 students interested in analyzing genetic data (target
gene and genomic data) of malarial parasites (protozoa
Main I am looking for
highly
motivated
students who
are interested
in gaining
research
experience. A
minimum of 3.7
GPA is required.
Basic
knowledge on
biology
(transcription/tr
anslation; DNA
structure and
replication) and
analytical/comp
utational skills
will be
considered as
selection
criteria.
Programming at
a basic level is
considered a
Biology,
Biochem,
Applied
Mathematic
s, Natural
Sciences
10/24/2019 3
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Ananias
Escalante
Ananias.Esc
alante@te
mple.edu
CST Biology Evolutionary
Bioinformatics and
Molecular ecology of
parasites
Understanding the evolutionary dynamics of parasites
demand integrating complex data. These projects require
the curation and organization of molecular data from
public databases and their analysis using a suite of
bioinformatics and phylogenetic methods. The projects
involve human malarias and related parasites in wildlife. By
interrogating single gene and genomic data, students will
participate in an individual research project seeking to
understand any of the following questions: the origin of
mutations linked to antimalarial drug resistance, the
evolution of genes encoding antigens considered vaccine
candidates, genes involved in the parasite invasion process
to their host red blood cell or vector, phylogeographic and
community-level (ecological) patterns of parasite
biodiversity, and molecular dating. These questions relate
to a variety of topics encompassing diverse fields from
public health to one health for those parasites linked to
diseases and from molecular evolution to community
ecology. Students will participate in regular lab meetings.
An interview with the PI is required.
Main No prior
experience is
required.
Biology majors
should be
interested in
learning
bioinformatics
while no-
biology majors
are expected to
learn relevant
concepts in
biology and
genomics. The
students in our
lab participate
in peer review
publications, so
organization
and good work
ethic are
required.
Biology,
Math
(applied or
basic),
Computer
Science,
Data
Science,
other
majors
could be
considered
Freshman -
Sophomor
e
preferred -
or Juniors
10/24/2019 4
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Ang Sun angsun@te
mple.edu
CST Biology Generate cell models
by using CRISPR-cas9
to knock out the RBL2
gene in normal and
cancerous colorectal
cell lines
As a member of the retinoblastoma tumor suppressor gene
family, RBL2, which encodes pRb2/p130, has been
investigated over 20 years. It is believed works as a tumor
suppressor. Its function in cell cycle regulation and histone
methylation has been widely reported. However, its
potential role in epigenetics, in particular regulating DNA
methylation, especially at the genome level, remains to be
well studied. As a portion of a larger project, this project
for undergraduates is going to focus on employing CRISPR-
cas9, a revolutionary genome-editing tool being developed
in recent years, to knockout RBL2 in a normal human colon
epithelial cell line (FHC) as well as a few colorectal cancer
cell lines. This will prepare good cell models for further
investigating the role of RBL2 in epigenetic regulation. In
the future, by comparing wild-type with RBL2 knockout cell
lines, the DNA methylation level in the promoter region of
a few critical tumor suppressor genes and oncogenes will
be examined using a quantitative, fluorescence-based, real-
time PCR method (MethyLight), and then confirmed by
pyrosequencing and bisulfite cloning sequencing; secondly,
methylation of LINE-1, which indicates the global
methylation of the cells will be tested. If promising results
are obtained, further study of the genome-wide DNA
methylation level change will be analyzed by Illumina 450k
methylation array or digital restriction enzyme analysis of
methylation (DREAM).
Main Biology
Anna
Moore
annarmoor
e@temple.
edu
CST Biology Unraveling the
mechanisms of
neuronal plasticity
Students will use molecular biology and genetic
approaches to investigate how different molecules regulate
the excitability of individual neurons. Techniques in the lab
will include PCR, subcloning, tissue culture,
immunolabeling, and confocal imaging.
Main A basic
understanding
of molecular
biology and
genetics is
encouraged. A
desire to learn
new techniques
and think
critically as well
Neuroscienc
e, Biology,
Biochemistr
y
10/24/2019 5
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Blair
Hedges
sbh@templ
e.edu
CST Biology Building a tree of life
with DNA data
This project involves working with DNA sequence data of
diverse organisms, and software, to help build the tree of
life and better understand evolutionary principles. It takes
place in the Center for Biodiversity and mostly involves
learning and using new computer tools and applications.
The center is located in SERC Building
Main strong
academics
normally
biology but
could be
any major
Blair
Hedges
sbh@templ
e.edu
CST Biology Conserving the
biodiversity of Haiti
This project involves helping efforts in Temple’s Center for
Biodiversity to learn more about the biodiversity of Haiti,
and to protect it. The multi-faceted team efforts include
discovery of new species, mainly through DNA sequencing
of samples collected in Haiti, ecological and evolutionary
studies, and educational and outreach components. The
center is located in SERC Building
Main strong
academics
normally
biology but
could be
any major
Brent
Sewall
bjsewall@t
emple.edu
CST Biology Large-scale analysis of
correlates of
susceptibility to white-
nose syndrome, an
emerging pathogen in
hibernating bats
White-nose syndrome is an emerging fungal pathogen
affecting hibernating bat populations of eastern North
America. Although it only appeared for the first time in
2006, it has already spread rapidly and has had devastating
effects, including the death of millions of bats across
hundreds of caves and mines. Such losses have important
implications for endangered species management,
conservation biology, and the ecology of natural
communities in North America. Little is known about the
disease, but most research to date has focused on bat-to-
bat transmission and site-level effects. Recently, however,
the disease has spread across a broad geographic area, and
an improved understanding of factors influencing both the
impacts and spread of the disease is needed. We will
investigate factors that may influence the susceptibility of
bats to the disease and its spread across large geographic
scales.
Main Coursework,
training, or
experience in
relevant
subjects such as
statistics,
Geographic
Information
Systems,
epidemiology,
public health,
ecology, or
conservation
biology. Also
strong
motivation for
research and
strong interest
Biology,
Environmen
tal Science,
Mathematic
s, Computer
Science, or
related -
Statistics,
Geographic
Information
Systems
(GIS), or
Epidemiolog
y (PBHL
3101)
courses or
equivalent (
already
10/24/2019 6
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Brent
Sewall
bjsewall@t
emple.edu
CST Biology Influence of vertebrate
frugivory on plant seed
dispersal and
germination
Vertebrate frugivores (fruit-eating mammal and bird
species) play an essential ecological role, by facilitating the
dispersal and germination of the seeds of a diversity of
plant species. Vertebrate frugivory is therefore a key
determinant of the reproduction of many plants. Frugivory
is especially important in the tropics, where frugivorous
primates, birds, and bats disperse seeds for up to 90% of
tree species in some forests. The foraging behavior and
community ecology of most species of frugivore, however,
are poorly understood. This lack of understanding hinders
our ability to quantify the impact of specific frugivore
species on the plant community or to conserve threatened
frugivore species. In addition, frugivores are particularly
vulnerable to hunting, fragmentation, and other human-
caused threats, but we still have only a rudimentary ability
to predict the effects of the loss of a specific frugivore
species on the plant community. The objectives of this
study, therefore, are (1) to investigate the influence of
frugivore feeding preferences and frugivore interspecific
interactions on seed dispersal and germination, (2) to
examine the ultimate impact of frugivore species on the
composition of plant species in natural ecosystems, and
the regeneration of plant species in disturbed ecosystems,
and (3) to investigate means by which an improved
ecological understanding of frugivores can contribute to
their conservation.
Main Coursework,
training, or
experience in
relevant
subjects such as
ecology,
statistics,
Geographic
Information
Systems, animal
behavior,
conservation
biology, and/or
French
language. Also
strong
motivation for
research and
strong interest
in this topic.
Biology,
Environmen
tal Science,
or related -
Intro Series
in Biology
(Bio 1111,
2112) or
equivalent
required.
Principles of
Ecology (Bio
2227)
strongly
preferred.
Statistics,
Animal
Behavior
(Bio 3254),
and/or
Conservatio
n Biology
(Bio 3307)
preferred.
10/24/2019 7
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Brent
Sewall
bjsewall@t
emple.edu
CST Biology Conservation biology
and community
ecology
My lab is investigating multiple questions in the fields of
conservation biology and community ecology, focusing on
understanding human drivers of change in ecological
systems and developing effective conservation strategies.
Ongoing research projects focus on (1) understanding
pollination and seed dispersal interactions among species
in ecological communities, (2) clarifying the influence of
emerging infectious diseases on wildlife populations, and
(3) identifying management strategies to mitigate the
negative effects of human activities on plant and animal
communities. Research takes place both on campus and
off-campus at field sites. Work may require travel to
remote sites, hiking, and long hours of data collection in
hot and sunny or rainy conditions. Work may also require
data entry, manipulation of data in spreadsheets, and/or
statistical analysis.
Main and
off-
campus
at field
sites (may
involve
travel)
Interest in the
field of
conservation
biology or
community
ecology;
experience and
skills in biology,
math, and other
relevant fields;
ability to
conduct field
work or engage
in data
manipulation or
both;
willingness to
work hard
under
Biology,
Environmen
tal Science,
Mathematic
s, or related
fields
Darius
Balciunas
darius@te
mple.edu
CST Biology Redundant roles of Fli
transcription factors in
regeneration
We are using a combination of molecular genetics
techniques, from conditional gene traps to CRISPR/Cas9
mutagenesis, to analyze the potential roles of two closely
related transcription factors, fli1a and fli1b, in fin and heart
regeneration in zebrafish. The project is currently being
carried out by a graduating senior, and should be taken
over by a junior or sophomore.
Main For more
information,
please see the
lab website
Biology,
Biochemistr
y
10/24/2019 8
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Darius
Balciunas
darius@te
mple.edu
CST Biology Precision genome
editing using
CRISPR/Cas9
Unlike humans, zebrafish possess a remarkable
regenerative capacity, including the ability to regenerate
their hearts after severe injury. We are working to figure
out which genes control this process and precisely how. To
achieve this goal, we are using the CRISPR/Cas9 system to
introduce precise changes into the zebrafish genome,
including integration of sequences coding for epitope tags.
We are looking for several students to join this effort. One
sub-project is to compare the efficiency of Cas9 nucleases
from two different species, Streptocossus pyogenes and
Streptocossus thermophilus. Other sub-projects include
screening for CRISPR/Cas9-induced genome editing events
and analysis of generated mutant lines.
Main For more
information,
please see the
lab website
Biology,
Biochemistr
y
Erik Cordes ecordes@t
emple.edu
CST Biology Ecological Project TBD - Please contact Dr Cordes Main Students who
are interested
in pursuing
graduate school
in the natural
sciences,
ecology and
evolution.
Biology and
environmen
tal science
majors are
preferred,
but the
position
would be
open to
other
students as Erik Cordes ecordes@t
emple.edu
CST Biology Molecular stress
response of deep-sea
corals
Field studies and laboratory experiments have revealed the
effects of various anthropogenic stressors (ocean
acidification, oil and dispersant exposure) on deep-sea
corals. The next step is to identify the molecular markers
that underlie these responses. Once identified, these may
reveal the potential for corals to be resilient to stress, or
for use as biomarkers to identify stressed populations in
future incidents. The research scholar(s) would be
responsible for processing samples in the laboratory for a
combination of physiological measures (protein/lipid
analysis, enzyme activity, etc.) and genetic analyses (qPCR,
RNAseq) that will contribute to our research on the effects
of human impacts on the deep sea.
Main Students who
are interested
in pursuing
graduate school
in the natural
sciences,
ecology and
evolution.
Biology and
environmen
tal science
majors are
preferred,
but the
position
would be
open to
other
students as
well.
10/24/2019 9
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Gianfranco
Bellpanni
gianfranco.
bellipanni
@temple.e
du
CST Biology pygo2 regulation of
WNT/ b-Catenin
pathway in zebrafish
b-catenin plays essential roles in cellular physiology being
the pivotal player for Ca+-dependent cell-cell adhesion and
for transduction of Wnt signaling. In the cytoplasm b-
catenin interacts with a-catenin and type I cadherins
mediating cell-cell adherence junctions adhesion, but, in
response to Wnt signaling, it is also transduced into the
nucleus where binds to DNA binding factors of the lef/tcf
family and activates transcription of a battery of Wnt
target genes. Aberrant activity of this factor has been
linked with congenital birth defects and cancer. In our lab
we are interested to study the molecular and cellular
mechanisms leading to the induction and specification of
D/V patterning in the zebrafish embryo via Wnt/ b-catenin
activity. One of the aspects of our research is to
understand at molecular and biochemical level how b-cat
ability to act as transcription factor is regulated by
different splicing variants of the nuclear factor Pygo2. The
goal of this project is to create by CRISPR/Cas9 induced
deletion a Null mutant for the pygo2 gene in the zebrafish
and compare the phenotypes of this mutation with the
phenotypes of other (milder) mutations in the pygo2 gene.
Main
10/24/2019 10
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Gregory
Smutzer
smutzerg@
temple.edu
CST Biology Examination of Human
Chemosensory
Function
Humans perceive five basic taste qualities, which include
sweet, sour, salty, bitter, and umami taste. In addition,
humans readily detect chemosensory irritants in the oral
cavity, in the nose, and on the surface of the skin. One
important chemical irritant is capsaicin, which is the
pungent chemical that gives chili peppers their unique
taste. Capsaicin is a vanilloid compound that activates
TRPV1 receptors in trigeminal nerves in the oral cavity, and
causes a stinging or burning sensation in the mouth. We
recently developed a novel delivery method for examining
capsaicin perception in the human oral cavity by
incorporating this hydrophobic compound in edible taste
strips. In addition, we recently identified compounds that
temporarily block the stinging sensation of capsaicin in the
oral cavity. Finally, we have found that capsaicin
chemosensation contains both an olfactory and a
trigeminal component. The goal of this research project is
to examine the effect of inhibitors on capsaicin perception
in the oral cavity by means of threshold studies, whole
mouth suprathreshold taste studies, and regional studies
on the tongue surface. Experiments will also be undertaken
to examine how these inhibitors block TRP receptors when
these gene products are expressed in a stable cell line.
Results from this study could lead to effective oral and
topical treatments for chronic pain.
Main Grade point
average of 3.0
or higher.
Ability to learn
basic lab
techniques.
Standard lab
skills include
ability to
prepare
solutions, ability
to use pipettes,
and ability to
carry out
protein assays.
Willingness to
learn new lab
techniques such
as mammalian
cell culture and
fluorescence
microscopy.
Biology,
Biochemistr
y, Chemistry
-
10/24/2019 11
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Gregory
Smutzer
smutzerg@
temple.edu
CST Biology Inositol 1,4,5-
Trisphosphate
Signaling in
Mammalian
Odontoblast Cells.
Although calcium is critical for the formation of dentin,
the origin and regulation of calcium during dentinogenesis
is not known. Odontoblasts are specialized cells that
secrete proteins and other molecules during the formation
of dentin in mammalian teeth. We reported that secretory
odontoblasts express high levels of the inositol 1,4,5-
trisphosphate (IP3) receptor/channel, along with an
associated GTP-binding protein. This receptor/channel
releases calcium from the endoplasmic reticulum of cells.
We are currently using cultured MDPC-23 cells as a model
for dentin formation. The goal of this research is to
demonstrate that the IP3 receptor, and a related GTP-
binding protein are expressed in differentiated MDPC-23
cells. In addition, calcium flux will be measured in
differentiated MDPC-23 cells by the calcium indicator dyes
Fura-2 and calcium green-1. These experiments will
demonstrate the importance of IP3 signaling in controlling
intracellular and extracellular calcium flux during the
formation of dentin by odontoblast cells
Main Willingness to
learn new lab
techniques. -
Standard lab
skills including
ability to
prepare
solutions, ability
to use pipettes,
ability to carry
out protein
assays, ability to
carry out SDS-
gel
electrophoresis,
and basic
computer skills
GPA of 3.0 or
higher in
science.
Biochemistr
y - A year of
General
Biology.
Biology
Chemistry
Jocelyn
Behm
jebehm@te
mple.edu
CST Biology Evaluation of “green”
certification programs
for biodiversity
Starbucks! Chipotle! Target! What do these companies
have in common? They sell products with “green”
certifications, but how green are they? This project
involves evaluating “green” certification programs for how
biodiversity is considered during the certification process.
Main Must be a
creative,
independent
thinker with
good attention
to detail.
Willingness to
learn new skills
Anyone
interested in
both
ecology and
sustainabilit
y (biology,
environmen
tal science, Jocelyn
Behm
jebehm@te
mple.edu
CST Biology Biodiversity and
Ecosystem Services
The reason we have food to eat, oxygen to breathe, and
we’re not up to our shoulders in dead leaves is due to the
services that ecosystems provide us. Despite the clear
importance of ecosystem services, we still have a lot to
learn about how the diverse species in ecosystems perform
these services. This project involves investigating how
biodiversity contributes to ecosystem services.
Main Attention to
detail,
willingness to
work outside,
organized
Biology,
Environmen
tal Science
10/24/2019 12
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Jody Hey hey@templ
e.edu
CST Biology Evolution and the
Human Genome
Student's will work on questions about how the human
genome has evolved. Some of the work may involve
comparisons with Ape genomes. Freshmen and
sophomores with interest in bioinformatics or in using
computers to address important biological or medical
questions.
Main all majors
Jody Hey hey@templ
e.edu
CST Biology Evolutionary Genomics Students will use genomic data to address questions about
natural selection and adaptation Freshmen and
sophomores with interest in bioinformatics or in using
computers to address important biological or medical
questions.
Main all majors
Jody Hey hey@templ
e.edu
CST Biology Population Genetics Students will help develop mathematical and statistical
models of evolutionary processes
Main Freshmen and
sophomores
with interest in
mathematical
and
computational
biology
Biology/Mat
h/Computer
Science
Joel
Sheffield
jbs@templ
e.edu
CST Biology Scanning Electron
Microscopy of
Developing Chick
Retina
We wish to expand our immunofluorescence studies of the
vascular structure of the chick retina with correlative
electron microscope analysis.
Main Fine Motor skills Biology or
Biochem
Junior or
senior
Joel
Sheffield
jbs@templ
e.edu
CST Biology Analysis of microglia in
retina and pecten
Immunohistochemical localization of specific antigens
during development of the chick retina.
Main Electrophoresis,
microscopy -
Bio 3096 is a
plus.
Biology
Joshua
Schraiber
joshua.schr
aiber@tem
ple.edu
CST Biology Detecting inbreeding in
ancient humans
We now have ancient DNA sequences from hundreds of
early modern humans spanning the last ~50 thousand
years of human evolution. Many of these individuals come
from nearby sites (such as individuals buried at the same
graveyard), raising the possibility that they are related to
each other. The student will develop an algorithm that
estimates the relatedness of ancient samples while
accounting for genotype uncertainty due to low coverage
sequencing data, and use it to determine how inbred
humans were during the colonization of Eurasia.
Main Some
programming,
some math,
willingness to
bang head
against hard
problems BIOL
2112 OR MATH
1044 OR CIS
1057
Math,
computer
science
10/24/2019 13
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Karen B.
Palter
palter@te
mple.edu
CST Biology Does hyperinsulinemia
affect the basal and
induced levels of Upd2
(leptin) in Drosophila?
Patients who are obese are at an increased risk of
developing metabolic syndrome, characterized by impaired
glucose tolerance, abnormal plasmid lipids, hypertension
and development of Type II diabetes. Our laboratory has
shown that Drosophila melanogaster lacking a functional
sialic acid pathway display a range of metabolic defects,
that are similar to those observed in patients with Type II
diabetes. We have demonstrated that one target of
sialylation is a potassium channel in the nervous system.
We propose that the metabolic defects are a result of
excess insulin secretion from insulin producing cells (IPC),
due to channel dysfunction. Marban and Roth (1996) have
shown that transgenic mice that secrete excess insulin
(hyperinsulinemic) become insulin resistant, the hallmark
of Type II diabetes. The mechanism of how
hyperinsulinemia leads to Type II diabetes is not
understood and is being actively studied. In both
Drosophila and humans, the fat body (flies) or adipose
tissue (humans) is a nutrient sensor, and in flies remotely
conveys the nutrient status to the insulin producing cells.
Under conditions of nutritional surplus, upd2, a petide
hormone is secreted from the fat body and binds receptors
on GABAergic neurons relieving their inhibitory effect on
the IPCs to which they project, resulting in fly insulin (dilp2,
3 and 5) secretion. Rajan and Perrimon (2012) recently
identified the cytokine Unpaired 2 (Upd2) as the functional
homolog of human leptin. In humans, leptin produced by
adipose tissue acts on the hypothalamus to regulate
appetite and energy expenditure rather than insulin
secretion although it has many target tissues. As upd2 is a
potent regulator of insulin secretion in response to
Main Motivation,
interest in
project and
academic
accomplishmen
t. Quick
learner, careful
and good at
quantitiative
skills.
Bio,
Biochem or
Neuroscienc
e -
Completed
Biology
1111 and
2112
10/24/2019 14
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Karen B.
Palter
palter@te
mple.edu
CST Biology Is there a functional
sialic acid pathway in
the insulin producing
cells (IPCs) of
Drosophila?
Our laboratory has previously shown that Drosophila
melanogaster lacking a functional sialic acid pathway
display a range of metabolic defects, that are similar to
those observed in patients with Type II diabetes. We have
demonstrated that one target of sialylation is a potassium
channel in the nervous system. We hypothesize that the
metabolic defects are a result of excess insulin secretion
from insulin producing cells (IPC), due to channel
dysfunction. However, we have been unable to detect any
RNA encoding the sialic acid pathway enzymes by in situ
hybridization in IPC cells in adult brains, and therefore,
cannot rule out that the metabolic defects could result
from defects in other brain neurons impacting the IPC cells.
In order to establish whether the sialic acid pathway is
functional in IPC cells, we have generated transgenic flies
carrying an ectopic copy of the sialic acid synthase gene
(SAS) under the Dilp2 (insulin promoter) that is active only
in IPC cells. Fly strains were generated that express this
transgene in a SAS 2d/2d (sialic acid synthese null)
background and therefore will express the sialic acid
synthase only in IPC cells. We wish to examine whether
such flies will still exhibit the neuronal phenotypes
characteristic of flies deficient in sialic acid (such as
neurodegeneration), but will no longer display metabolic
defects, establishing that the metabolic defects were due
solely to loss of sialic acid in the IPC cells. A variety of both
behavioral and biochemical assays will be used to assay for
metabolic defects.
Main Motivation,
interest in
project and
academic
accomplishmen
t. Quick
learner, careful
and good at
quantitiative
skills.
Bio,
Biochem or
Neuroscienc
e -
Completed
Biology
1111 and
2112
10/24/2019 15
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Karen
Palter
palter@te
mple.edu
CST Biology Investigating the
mechanism of insulin
resistance in Type II
diabetes
Our laboratory has previously shown that Drosophila
melanogaster lacking a functional sialic acid pathway
display a range of metabolic defects. We hypothesize that
the metabolic defects are a result of excess insulin
secretion from the insulin producing cells (IPC). We have
generated transgenic flies carrying an ectopic copy of the
sialic acid synthase gene (SAS) under a Dilp2 (insulin
promoter) that is active only in IPC cells. Fly strains were
generated that have this transgene in a SAS2d/2d
background (null for SAS) and therefore will express the
sialic acid synthase only in IPC cells. All transgenic flies are
male sterile and all exhibit defects in locomotor activity, as
did the original SAS mutant strain. However, all rescued
strains no longer exhibit the metabolic defects
characteristic of the SAS mutant strain, strongly suggesting
that such defects were due to loss of sialic acid directly in
the IPC cells. We have demonstrated that one target of
sialylation (the addition of the terminal sugar to
glycoproteins) is a potassium channel in the nervous
system. We propose that the result of excess insulin
secretion from insulin producing cells (IPC) were due to
channel dysfunction. Marban and Roth (1996) have shown
that transgenic mice that secrete excess insulin
(hyperinsulinemic) become insulin resistant, the hallmark
of Type II diabetes. The mechanism of how
hyperinsulinemia leads to Type II diabetes is not
understood. Our laboratory uses flies as a model organism
to investigate the mechanism of how flies become insulin
resistant and progress to diabetes. We are currently
examining the levels of intermediates in the insulin
signaling pathway in normal and mutant flies using both
Main Motivation and
interest in
research.
Biology 2112
Biochemistr
y or Biology
10/24/2019 16
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Maria
Pacheco
tug00270@
temple.edu
CST Biology Biodiversity and
evolution of parasites
All known multicellular organisms harbor diverse
assemblages of dependent species, many of which are
considered parasites. Despite a growing awareness of the
importance of dependent species for biodiversity,
parasitological investigations have largely focused on the
harm caused by parasites to their hosts. However, the
ecology and evolutionary biology of parasitic organisms are
worthy of study in their own right despite the challenges
that these organisms pose as relatively unknown elements
of biodiversity. Indeed, our ability to understand the
processes shaping parasite diversity and to mitigate threats
to that diversity is limited by gaps in our knowledge of
issues such as species delimitation, population structure
and spatial distribution, and the dynamics of assemblages
which include multiple parasite and multiple host species.
This project seeks to characterize multiple dimensions of
the eukaryotic endoparasite biodiversity. In particular, we
will give special attention to malarial parasites in the genus
Plasmodium and other related parasitic protozoa. These
species belong to a diverse monophyletic group that is
found in a broad range of vertebrate hosts, including
primates, lizards and birds. The long-term goals of this
investigation are (i) to characterize geographic patterns of
parasite assemblages in birds and primates; (ii) to explore
the functional and ecological interactions of a group of
malaria parasites sharing one or more hosts in common;
and (iii) to investigate the genetic diversity, host
adaptations and speciation of malaria parasites infecting
several host species. The students’ main role will be to
assist in developing a database of parasites genetic data
and their host by mining published data. They will also
Main Highly
motivated. A
minimum of 3.7
GPA. Basic
knowledge on
biology
(transcription/tr
anslation and
DNA
replication),
analytical/quant
itative skills and
curiosity are
required.
Programming at
a basic level is
considered a
plus, but it is
not required.
Students should
interview with
the PI. Our
expectation is
that the
selected
candidates will
continue to
work with us
after the
summer.
Traditionally,
Biology,
Applied
Math,
Natural
Sciences,
Information
Science and
Technology,
Computer
Sciences
10/24/2019 17
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Matthew
Helmus
mrhelmus
@temple.e
du
CST Biology The invasion
meltdown and how to
stop it
In Pennsylvania, the spotted lanternfly (Lycorma delicatula)
is a particularly worrisome invasive. In 2014, it invaded
Berks County on material imported from Asia. It destroys
vineyards, orchards, and timber (industries worth $18
billion to Pennsylvania). It rains showers of sticky sap on
homeowners and can spread to new locations by
hitchhiking on anything kept outdoors like a car. It has
spread outside the Commonwealth, to Virginia; economic
losses across the U.S. will be disastrous if it expands
unchecked. Contact Dr. Helmus to help the iEco Lab stop
the meltdown.
Main BIO, Math,
CIS,
EES,Phys, &
Chem
Matthew
Helmus
mrhelmus
@temple.e
du
CST Biology The genomics of
scared tadpoles
Tadpoles just want to grow up to become frogs, but in
nature there are plenty of predators. Luckily, tadpoles have
a defense--when exposed to predators, tadpoles can
radically change their body shapes and musculature so that
they are harder for predators to catch. The goal of this
project is to analyze experimental genomic data (already
collected) to determine gene expression during body
changes. Bioinformatics that may be used are: R statistical
programming, Galaxy bioinformatic pipelines and
BLAST2GO software.
Main Basic computer
programming
Courses in
Genomics or
Computer
Programmin
g
Matthew
Helmus
mrhelmus
@temple.e
du
CST Biology Are there universal
patterns in
biodiversity?
Natural selection has caused a spectacular amount of
biodiversity, from flying frogs to legless lizards, yet this
evolution is not random. For example, on distant oceanic
islands, species have evolved from the same types of
natural selection, converging to similar body shapes and
sizes. The goal of this project is to identify these universal
patterns in biodiversity using specimens of lizards and frogs
from across the Caribbean. The student will measure the
body traits of the specimens and then build, using the R
statistical programming language, genetic trees of
evolutionary relationship of species to identify
convergence in biodiversity.
Main Basic excel Biology,
Environmen
tal Science
10/24/2019 18
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Rachel
Spigler
rachel.spigl
er@temple
.edu
CST Biology The impact of
inbreeding on plant
population growth
What factors influence whether populations of organisms
increase, remain stable, or decline to extinction? This
project will investigate how genetic factors (inbreeding)
might impact population growth of a native wildflower
plant. Students will work in the plant facility on campus,
with opportunities to work out in the field in experimental
plant populations.
Field
locations
in PA and
MD
Strong
academic
record.
Enthusiasm and
attention to
detail. Ability
and willingness
to perform field
work as
schedule allows.
Biology,
Environmen
tal Science
Rachel
Spigler
rachel.spigl
er@temple
.edu
CST Biology Chemical analysis of
floral nectar
Floral nectar is a critical resource for animal pollinators,
essential for metabolism, growth, and reproduction. Plant
species can vary markedly in both the quantity and quality
of nectar they offer. Students will aid in the analysis of
nectar amino acids, sugars, and lipids in various species in
wild populations using HPLC and GCMS.
Main Strong
academic
record and
background in
chemistry.
Attention to
detail and
organizational
Biology,
Chemistry
Rachel
Spigler
rachel.spigl
er@temple
.edu
CST Biology The impact of plant
mating patterns on
population growth
What factors influence whether populations of organisms
increase, remain stable, or decline to extinction? This
project will investigate how genetic factors (inbreeding)
might impact population growth of a native wildflower
plant. Students will work in the plant facility on campus
andout in the field in experimental plant populations.
Main
Campus
& Field
sites
Strong
academic
record.
Enthusiasm and
attention to
detail. Ability
and willingness
to perform
greenhouse and
Biology,
Environmen
tal Science
Rachel
Spigler
rachel.spigl
er@temple
.edu
CST Biology Plant-pollinator
interactions
Nearly 90% of flowering plants rely on animal pollination
for successful seed production, including 75% of the
world’s leading food crops. For pollinators, nectar and
pollen represent an essential resource for metabolism,
growth and survival. We are studying dynamics of this
critical partnership within an entire community of plants
and their pollinators across grasslands in central and
southeastern Pennsylvania. Students will be involved in lab
research, involving microscopy, digital imaging, pollinator
observation/identifcation.
Main Strong
academic
record.
Enthusiasm and
attention to
detail.
Biology,
Environmen
tal Science
10/24/2019 19
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Rob
Kulathinal
robkulathin
al@temple.
edu
CST Biology Genomics of speciation Is speciation driven by genes involved in reproduction? In
this project, the student will: 1) identify genes under
selection using evolutionary genomic approaches and/or 2)
knock-down those genes using ready-made RNAi lines via
our high-throughput behavioral arenas. The student will
be trained by an active team of undergraduate and
doctoral students who are already applying these powerful
approaches using Drosophila.
Main Determination,
curiosity, and
computationally-
inclined
Biology,
Computer
Science
Tonia Hsich sthsieh@te
mple.edu
CST Biology Control mechanisms
for counting
unexpected
perturbations during
bipedal running in
lizards
Main Biology
Weidong
Yang
weidong.ya
ng@temple
.edu
CST Biology Super-resolution study
of interactions and
competitions in normal
and cancer cells
Super-resolution light microscopy won the Nobel Prize in
Chemistry in 2014. In our lab, we combine super-resolution
microscopy with single-molecule tracking, fluorescence
recovery and innovative molecular biology techniques to
study the following projects: 1) interactions between
human cells (normal and cancer cells) and viruses. 2)
trafficking of RNAs, vesicles and proteins through the
nuclear pore complexes in live human cells. 3) the gating
mechanism for macromolecules transport into the cilium of
human cells.
Main Biology,
biochemistr
y, biophysics
and the
relevant
10/24/2019 20
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Weidong
Yang
weidong.ya
ng@temple
.edu
CST Biology Study protein and RNA
in cancer cells
We are highly motivated to develop innovative research
tools to meet the needs of solving challenging biological
and biomedical problems, as we have done in the past and
will be doing in the future. Currently, by developing and
employing high-speed super-resolution microscopy
techniques, our research aims to solve two critical
transport mechanisms involving three sub-cellular
organelles in eukaryotic cells: nucleus, cytoplasm and
primary cilium. Macromolecular trafficking among these
compartments is suggested to be gated by two unique
machineries. One is the nuclear pore complex (NPC)
embedded in the nuclear envelope that mediates the
bidirectional trafficking of proteins and RNAs between the
cytoplasm and the nucleus; the other is the transition zone
(TZ) located at the base of cilium that regulates the entry of
membrane and cytosolic proteins into the cilium. Due to
the challenges in elucidating kinetics and real-time
transport routes for macromolecules through the sub-
micrometer NPC or TZ in live cells, however, the
fundamental gating mechanisms in either of these two
machineries, remain obscure. Moreover, these transport
mechanisms are not only the fundamental unanswered
questions in cell biology, but also are closely associated
with human diseases. For example, dysfunction of the
nuclear transport through the NPC are linked to numerous
human diseases including leukemias, cancers, and primary
biliary cirrhosis. Also, defects in ciliary structure and/or
function causes a variety of diseases (called ciliopathies)
such as cystic kidney disease, nephronophthisis (NPHP),
and retinitis pigmentosa. Thus, the fundamental
knowledge of understanding the gating mechanisms in
Main Biology,
Biophysics,
Physics,
computer
science
Sergei Pond spond@te
mple.edu
CST Biology and
iGEM
Software development
and Bioinformatics
Utilize and develop open-source software to explore DNA
mutations. Using high-performance computing, statistical
techniques, and the latest web technologies, we provide
methods that researchers use to answer questions about
their genetic sequence data. All computational
development and research takes place within iGEM located
in the SERC building (igem.temple.edu).
Main Computer
Science,
Mathematic
s, Biology,
Physics
10/24/2019 21
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Sudhir
Kumar
s.kumar@t
emple.edu
CST Biology and
iGEM
Software development
and Bioinformatics
We develop software (including smartphone apps) for
analyzing biological data in the fields of Genomics and
Medicine. All developments will be in a new institute in
SERC.
Main Knowledge of
computer
programming
and/or app
development
All majors
Sudhir
Kumar
s.kumar@t
emple.edu
CST Biology and
iGEM
Personalized medicine
and evolutionary link
between DNA and
disease
We all have many DNA differences from others. Which of
these personal differences cause disease? We use
computers to study disease variation in humans and
compare it to differences humans show with other species.
We also build predictive methods and tools. All
computational research will be in a new institute in SERC.
Main Interest in the
field,
knowledge of
computers
All majors
Sudhir
Kumar
s.kumar@t
emple.edu
CST Biology and
iGEM
Genomics, Medicine,
and Evolution
(computer based)
Students will carry out biological and biomedical research
using computers with emphasis on DNA data analysis.
Biomedical questions will be focused on Genome Medicine.
Biological questions will be on building the tree of life.
Depending on the student's background, you may conduct
primary data analysis research and/or assist in developing
new methods, software, and databases.
Main Freshmen and
sophomores
with interest in
biology,
medicine, or
computers. No
requirements,
as the projects
will be tailored
Biology,
Computers,
Physics,
Anthropolog
y,
Pharmacy,
Chemistry
10/24/2019 22
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Sudhir
Kumar
s.kumar@t
emple.edu
CST Biology and
iGEM
Genomic Medicine and
Tree of Life
Evolutionary analytics of mutations, genomes, and species
is the primary focus of my research group. We use
integrative and comparative approaches to make
fundamental discoveries in the fields of medicine,
evolution and genomics. The common theme of all our
research is the use of comparative analysis to reveal
genome differences that are outcomes of natural selection
on novel mutations arising in all species during their
propagation from generation to generation and in an
individual’s lifetime. The resulting patterns of conservation
and divergence of our DNA enables us to conduct research
investigations ranging from establishing the tree of life
scaled to time (TimeTree of Life) and to forecasting
disruptive mutations found in personal germline and
somatic genomes (Phylomedicine). In these pursuits of
biological discoveries, we are also developing new
statistical methods and computer algorithms to quickly
analyze large-scale datasets in these disciplines. We also
develop and disseminate many high-impact software tools
(MEGA and myPEG) and databases/applications (TimeTree
and FlyExpress).
Main Prefer freshmen
or sophomores
interested in
devoting
multiple years
working in our
group so they
can carry out
real research
and
development
projects,
including the
writing of
research papers
and/or
development of
software and
database tools.
Successful
students will be
provided year-
Biology,
Computer
Science,
Chemistry,
Physics,
Biomedical
engineering,
and other
biology-
related
department
Steve
Flemming
sfleming@t
emple.edu
CST Chemisry Virtual Reality (VR) of
Bio-Organic Reaction
Animations (BioORA)
In collaboration with Gillian Queisser. The teaching tool Bio-
Organic Reaction Animations (BioORA) has been developed
to assist student learning. BioORA is available online and it
covers topics that include enzyme chemistry, lipids, nucleic
acids, and carbohydrates. The animations that are included
in the program are based on 3D data from crystal
structures found in the Protein Data Bank (PDB). This
research project involves developing a pipeline from PDB
files to 3D visualization using Unity3D and Oculus Rift
Virtual Reality hardware. The ultimate goal would be to
generate a new VR-based teaching tool for bio-organic
chemistry.
Main Students
working on this
project would
need to have a
basic
knowledge
of scripting
and/or object-
oriented progra
mming languag
es and an
interest in
learning virtual
chemistry,
biochemistr
y, CIS, math
Sophomor
e, Junior
or Senior
Ann
Valentine
ann.valenti
ne@temple
.edu
CST Chemistry Bioinorganic Titanium
Chemistry
The Valentine Lab is interested in hydrolysis-prone metal
ions of biological relevance. The student will investigate
possible ligand systems for stabilization of titanium(IV) in a
water environment, will make and characterize new
inorganic coordination compounds, and will evaluate their
interactions with biomolecules
Main intelligence
enthusiasm
conscientiousne
ss - will teach
skills necessary
chemistry
biochemistr
y
Sophomor
e, Junior
10/24/2019 23
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Carol
Manhart
carol.manh
art@templ
e.edu
CST Chemistry DNA Mismatch Repair
Mechanisms
The Manhart Lab is interested in how proteins that
spellcheck and repair the DNA code identify targets and act
with the required precision necessary to maintain genomic
integrity. Students will investigate catalytic mutants of
repair proteins in in vitro repair reactions and other
biochemical assays. Students will learn molecular biology,
protein purification, and biochemical techniques to
characterize these proteins. Intelligence, organization,
enthusiasm for learning new things,
conscientiousness/good lab citizenship are required. Also
required is a strong interest in biochemistry and enzyme
function.
Main Chemistry,
biochemistr
y
Sophomor
e, Junior
Daniel
Strongin
dstrongi@t
emple.edu
CST Chemistry Reactivity of Pyrite and
Acid Mine Drainage
The iron sulfide, pyrite, is found at active and abandoned
coal mining sites. Its decomposition in the environment
leads to acid mine drainage (sulfuric acid generation) which
is a significant problems for coal mining companies and the
surrounding environment. The goal of the project is to look
into strategies to suppress the oxidation of pyrite and the
resulting acid generation.
Main Motivation
Academic
performance -
Introductory
Chemistry
Courses with
Laboratory.
Chemistry
ESS
Eric
Borguet
eborguet@
temple.edu
CST Chemistry Combining Photons,
Electrons and
Nanoparticles for
Plasmonic Sensing and
Catalysis
Students will develop and use nanoscale plasmonic
materials for rapid, high sensitivity detection of biological
and chemical agents, as well as catalytic conversion. They
will learn to use a variety of analytical techniques such as
spectroscopy, Atomic Force Microscopy Curiosity and
persistence - Interest in research - Aptitude for careful
laboratory research - - Undergraduate researchers in my
group typically present at local, regional and even national
conferences. Many have been co-authors on publications.
Main Chemistry,
Physics
Sophomor
e or Junior
10/24/2019 24
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Eric
Borguet
eborguet@
temple.edu
CST Chemistry Laser Vibrational
Spectroscopy and
Dynamics of Molecular
Species at Bio and
Geochemical Interfaces
Research involves learning to use ultrafast lasers (we make
some of the shortest infrared pulses in the world) to
perform vibrational Sum Frequency Generation (SFG) a
technique that provides sensitivity to single molecualr
layers. Students will investigate water, arguably the most
important molecule on the planet at interfaces of biological
and geochemical relevance. Students will learn about
surface chemistry, biointerfaces, geochemistry and laser
spectroscopy.
Main Curiosity and
persistence -
Interest in
research -
Aptitude for
careful
laboratory
research - -
Undergraduate
researchers in
my group
Chemistry,
Physics
Sophomor
e or Junior
Frank
Spano
spano@te
mple.edu
CST Chemistry Photophtsical
Properties of
Histochemical Dye
Aggregation
Main Chemistry
10/24/2019 25
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
George A.
Petersson
gpetersson
@temple.e
du
CST Chemistry Making high accuracy
affordable through DFT
The coupled-cluster singles and doubles with perturbative
triples complete basis set limit, CCSD(T)/CBS limit [J. Chem.
Phys., 138, 144104 (2013), J. Chem. Phys. 143, 214110
(2015)] offers very high accuracy for much of
thermochemistry, but these calculations are very
expensive. If we limit the CCSD(T) calculations to the
valence electron correlation energy, the remaining small
corrections can be treated by DFT with little loss of
accuracy at dramatically reduced cost. For example, we
recently published [J. Chem. Phys. 143, 214111 (2015)] a
core-valence density functional that requires less time than
a single SCF iteration, but reproduces the CCSD(T)/CBS core-
valence correlation energy to within ±0.27 kcal/mol rms
error. We are now developing density functional methods
covering the elements H through Kr for the geometry
(±0.011 Å which corresponds to ±0.065 kcal/mol rms error
in the energy), zero-point-energy (±0.063 kcal/mol rms
error), scalar relativistic corrections (±0.18 kcal/mol rms
error), and spin-orbit coupling (±0.21 kcal/mol rms error).
These errors all compare favorably with the inherent error
in CCSD(T) energies (±0.56 kcal/mol rms error) with respect
to Full CI energies for these species. This work will include
extending core-valence density functional to the third-row
including the transition metals, and improving on the
generalized Douglas-Kroll-Hess relativistic DFT calculations
of the spin-orbit coupling interactions.
Main The
undergraduate
research
participant
should have a
basic
knowledge of
quantum
mechanics and
computer
programing.
Chemistry,
Physics,
Computer
Science
sophomor
es or
Juniors
10/24/2019 26
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
George
Petersson
tue44197@
temple.edu
CST Chemistry Spectra of Acridone D
erivatives
Sub tituted acriones are useful as fluorescent dyes for
studies of protein folding. A collaboration with
experimental studies at the University of Pennsylvania will
employ ab initio caculations of
electronic absorption and emission specra to determine
what structural modifications would enhance the useful
ness of these dyes. Method
will include CIS(D), EOM- CSD, and TDDFT. The student will
learn to create input and interpret output using
the program GassView, and learn to run the program
Gaussian16 on the Owl’s Nest Custer at Temple
University. It might also be possible to measure an e
xperimenta l spectrum at Penn if the student wants to.
Main The
undergraduate
research
participant
should have a
basic
knowledge of
quantum
mechanics such
as having
completed
CHEM 3302, or
PHYS 2796 or
PHYS 3701. The
departmental
Chemistry
or CS
Junior or
Senior
George
Petersson
tue44197@
temple.edu
CST Chemistry Interface between
Gaussian16 WindNMR
Ab initio calculated nmr spectra are useful for the
interpretation of expe rimental spectra and m lecular
structural assignments. However, it is very tedious to paste
calculated chemical shifts and spin-spin coupling constants
into a program that simulates a high resolution nmr
spectrum. This project involves writing computer code to
read a Gaussian16 output file and create a data file for the
pro ram WindNMR. This work is a collaboration with
colleagues at the Kitas to Institute in Tokyo. The
undergraduate research participant’s background in
Chemistry and Spectroscopy is far less important than an
aptitude for writing computer code. The departmental
major or class year are unimportant.
Main Chemistry
or CS
Junior or
Senior
Graham
Dobereiner
dob@temp
le.edu
CST Chemistry Exploring the influence
of Lewis Acids on
Organometallic
Compounds
Organometallic complexes, which feature metal-carbon
bonds, underpin key catalytic reactions in chemical
industry. This project will explore the synthesis of new
complexes using air-free technique, and investigate the
reactivity of these complexes in new chemical reactions.
Main Prior classroom
laboratory
experience
(General
Chemistry, and
preferably
Organic
Chemistry
10/24/2019 27
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Michael J.
Zdilla
mzdilla@te
mple.edu
CST Chemistry Preparation and
testing of solid
electrolytes for battery
applications
We are seeking undergraduates to aid in the synthesis of
salt-organic hybrid electrolyte materials by co-
crystalizaiton methods, and the assessment of their
conductivity using electrochemical techniques.
Main GPA,
Intent to pursue
Graduate
education.
Skills from
General
Chemistry -
General
Chemistry
completed,
Organic
chemistry
Sophomor
e, Junior
or Senior
Robert J.
Levis
rjlevis@te
mple.edu
CST Chemistry Stand-Off Detection of
Molecules using
Advanced Laser
Technology
The ability to detect molecules at distances up to 50
meters is valuable for many applications including
explosives detection, analyzing smoke stacks and probing
urban environments. This project will involve working with
femtosecond laser filamentation ("a light saber") and a
new Raman spectroscopy method developed in the Center
for Advanced Photonics Research. Interested students
should read the publications on the Center's web site
Main independent
motivation
Neuroscienc
e, Cell and
Developmen
tal Biology
Sophomor
e, Junior,
Senior
Robert J.
Levis
rjlevis@te
mple.edu
CST Chemistry Nanomaterials by
Design
Nanomaterials include size as a design parameter for a
material’s properties. For instance the color of a quantum
dot changes as the size changes from 100nm to 10nm. The
aim of this project is to discover new nanomaterials using
femtosecond laser processing of precursors including
chemical compounds, bulk metals, semiconductors and
organic materials. The project involves the use of lasers
and state of the art optics as well as characterization
methods including UV-VIS, mass spectrometry,
transmission electron microscopy, dynamic light scattering
and a nanoparticle size analyzer.
Main independent
motivation
Neuroscienc
e, Cell and
Developmen
tal Biology
Sophomor
e, Junior,
Senior
Robert
Stanley
rstanley@t
emple.edu
CST Chemistry Promiscuous enzymes
and cofactor analogs
Enzymes are considered to be very specific chemical
factories, recognizing and processing only very specific
substrates. In contrast, cold-adapted enzymes, from
organisms living at or below 0C, are rather promiscuous,
opening up the possibility of generating product analogs of
greater variety. You will exploit this characteristic by
cloning, overexpressing, and characterizing a few cold-
adapted enzymes that make potential useful cofactor
analogs.
Main Experience with
protein
biochemistry
and molecular
biology
techniques a
real plus.
Biochemsitr
y,
Chemistry,
Physics,
Biology
Sophomor
e, Junior
10/24/2019 28
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Ross Wang rosswang@
temple.edu
CST Chemistry Chemical probes to
study post-
translational
modifications
Chemical biology approaches to the mechanism study,
diagnosis, and treatment of human diseases
II. Chemical proteomics to identify key proteins for the
onset of cancer and inflammatory disorders.
Main Having
completed
General
Chemistry,
Organic
Chemistry I with
a grade of B or
Chemistry,
Biology,
Biochemistr
y,
Pharmaceuti
cal
Sophomor
e,
Junior, or
Senior
Ross Wang rosswang@
temple.edu
CST Chemistry Development of novel
imaging agents for
image-guided cancer
therapy
Chemical biology approaches to the mechanism study,
diagnosis, and treatment of human diseases
Main Having
completed
General
Chemistry,
Organic
Chemistry I with
a grade of B or
Chemistry,
Biology,
Biochemistr
y,
Pharmaceuti
cal
Sophomor
e,
Junior, or
Senior
Ross Wang rosswang@
temple.edu
CST Chemistry Design and synthesis of
antibody mimics
Chemical biology approaches to the mechanism study,
diagnosis, and treatment of human diseases Having
completed General Chemistry, Organic Chemistry I with a
grade of B or higher. Preferably with prior laboratory
experience in Chemistry and Biochemistry
Main Chemistry,
Biology,
Biochemistr
y,
Pharmaceuti
cal
Sophomor
e,
Junior, or
Senior
Sarah
Wengryniu
k
tuf76212@
temple.edu
CST Chemistry Two possible projects:
"Evaluation of IL-8
inhibitors for inhibition
of cancer metastasis"
and "Development of
novel cyclic ether
synthesis from tertiary
Two possible projects: "Evaluation of IL-8 inhibitors for
inhibition of cancer metastasis" and "Development of novel
cyclic ether synthesis from tertiary alcohols"
Main Having
completed both
Organic 1 and
Organic 2 with a
B or higher in
both courses.
Strong letter of
Chemistry Sophomor
e, Junior,
Senior
Spiridoula
Matsika
smatsika@t
emple.edu
CST Chemistry Modeling reactions in
chemistry and biology
Processes initiated by light play an important role in
biological systems with primary examples found in
photosynthesis, vision, and photochemical damage and
repair in DNA. We use computational methods to study
processes important in biology, chemistry, astrochemistry,
and other areas. Part of this research facilitates
development of new fluorescent probes.
Main Chemistry,
Physics,
Biochem,
CIS
Freshman,
Sophomor
e, Junior,
Senior
10/24/2019 29
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Spiridoula
Matsika
smatsika@t
emple.edu
CST Chemistry Studying the
photophysics and
photochemistry of
DNA using quantum
mechanics
Processes initiated by light play an important role in
biological systems with primary examples found in
photosynthesis, vision, and photochemical damage and
repair in DNA. A fundamental understanding of these
processes reveals the way nature works and also provides
ideas on how to mimic or alter these mechanisms to our
own benefit. The current project focuses on studies of the
photophysical behavior of DNA bases and their fluorescent
analogs. When UV radiation is absorbed by DNA,
photochemical reactions may occur which can lead to
photochemical damage. DNA, however, is proven to be
quite photostable, since the absorbed energy can be
converted to harmless heat. We examine what happens
after one or two bases absorb light, and what is the
fundamental mechanism for making these molecules
photostable. We use quantum mechanics to study these
processes. Large scale computations are employed to
solve the Schroedinger equation approximately, and the
results are analyzed to provide the electronic structure,
properties and reactivity of the molecules studied. Apart
from quantitative answers we also obtain qualitative
pictures by visualizing orbitals and other properties, which
give us physical insight.
Main Students should
be motivated,
interested in
research and
computational
work, with an
aptitude for
math.
Chemistry,
Physics
Junior or
Senior
Stephanie
Wunder
slwunder@
temple.edu
CST Chemistry Nanopartile/Lipid
Project
Nanoparticles have high surface/volume ratios so that
characterization of the material on the surface is very
important in applications such as drug/DNA delivery and
nanocomposites. The phase transitions, conformations and
adsorption isotherms of lipids and polymers (both natural-
proteins, DNA, RNA and synthetic-polymers) on silica
nanoparticles of different sizes (from 5-500nm) will be
investigated by a variety of analytical techniques such as
HPLC, FTIR, Raman and fluorescence spectroscopies, and
thermal analysis.
Main Willingness to
work hard,
understanding
of experimental
techniques and
the importance
of obtaining
reproducible
data - wet
chemistry
techniques
Chemistry,
Biochem -
organic
chemistry I,
analytical
chemistry
Junior or
Senior
10/24/2019 30
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Stephanie
Wunder
slwunder@
temple.edu
CST Chemistry Lithium Batteries &
Fuel Cells: Materials
preparation &
Characterization
In order to improve the performance of lithium ion
batteries and fuel cells, it is critical to make advances in
many aspects of the materials used in the electrodes,
electrolytes and separators. This project involves preparing
and characterizing novel nanomaterials to be employed as
separators for NaBH4 fuel cells and lithium ion batteries. In
particular we have functionalized what are called
polyoctahedral silsesquioxanes (POSS), which are nano
silica (SiO1.5) cubes with eight groups at the corners that
contain dissociable Li+, OH- ions or polyethylene glycol.
The project(s) involve incorporation of these POSS
materials with polymers, and the characterization of the
nanocomposites by calorimetric and electrochemical
methods.
Main Willingness to
work hard,
understanding
of experimental
techniques and
the importance
of obtaining
reproducible
data - wet
chemistry
techniques
Chemistry,
Biochem -
organic
chemistry I,
analytical
chemistry
Junior or
Senior
Vincent
Voelz
voelz@tem
ple.edu
CST Chemistry Molecular simulation
of proteins and
peptide mimics
This work involves computational modeling of proteins and
peptide mimics. We simulating the molecular dynamics of
molecules on high-performace computing platforms, to
make predictions about folding and binding.
Main Some
combination of
programming
experience,
math skills and
Math,
physics,
computer
science and
chemistry
Sophomor
e or Junior
Yi Rao yirao@tem
ple.edu
CST Chemistry Two-dimensional
Layered Organic-
Inorganic Hybrid for
Photovoltaic
Applications
We will synthesize novel 2D layered materials for
photovoltaic applications. We evaluate and control the
elementary processes that govern the properties and
performance of perovskite materials in photovoltaic and
optoelectronic devices illustrated by dye sensitized solar
cells (DSSC) and light emitting diodes (LED). Application of
these unprecedented measurement capabilities to relevant
materials issues benefits from inter-dependent programs in
materials design, preparation, and processing.
Main Physical
chemistry and
organic
chemistry
chemistry or
physics
Junior,
senior
10/24/2019 31
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Yi Rao tuf42202@
temple.edu
CST Chemistry Photovoltaic
applications of
multiple exciton
generation from Ge
nanocrystals
In this undergraduate research, we aim to investigate both
Ge nanocrystal inorganic materials interactions with light
and the potential for unique photovoltaic applications,
including the generation of multiple carrier generations in
Ge nanocrystals. It includes two parts. Part A:
Characterization of linear optical properties of Ge
nanocrystals using absorption, fluorescence, and Raman
scattering spectroscopy. The students will investigate the
optical characteristics of inorganic silicon nanocrystals
using a range of available spectroscopic tools. These
measurements will be performed on samples consisting of
Ge nanocrystals of different sizes at different solvents. The
aim of part A is to understand the basic optical properties
of the potential materials for multiple exciton generation,
and to identify the growth conditions for production of Ge
nanocrystals that exhibit the appropriate band gap and
very high structural quality. Part B is to investigate surface
properties of Ge nanocrystals. These experiments will be
carried out using femtosecond laser systems. For inorganic
Ge nanocrystals, second order properties and surface
modifications of Ge nanocrystals will be examined. The
purpose of the research is to expose undergraduate
students to state-of-the-art ultrafast optical spectroscopy,
and to hands-on train the students how to perform
experiments, analyze data, and present experimental
results.
Main Chemistry,
physics,
engineering
Sophomor
e, Junior,
Senior
10/24/2019 32
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Yugang Sun ygsun@te
mple.edu
CST Chemistry Understanding
transformation of
colloidal nanoparticles
The behavior of colloidal nanoparticles in liquid solution is
very complex and the accurate description of their
behavior is still absent. This project will target this ground-
challenging problem by working with senior graduate
researchers. This research will rely on the group's unique
ability to use the in situ high-energy synchrotron x-ray
techniques to probe the nanoparticle evolution processes
in real time and even under real reaction conditions. This
capability enables the collection of the unprecedented
data, which are impossibly achieved with traditional
methods, from colloidal nanoparticles. We will process the
in-situ data to develop appropriate models to understand
the complex behavior of colloidal nanoparticles. The
understanding will be helpful to design the synthesis
protocol for producing the best nanomaterials.
Main Chemistry Junior,
Senior
Yugang Sun ygsun@te
mple.edu
CST Chemistry Microfluidic synthesis
of graphene-supported
quantum dots for
photocatalysis
This project seeks to use the home-built microfluidic
reactor for synthesizing graphene-supported
semiconductor quantum dots, which can adsorb solar
energy to drive useful chemical reactions (i.e.,
photocatalysis). The student will use the method recently
developed in my group to synthesize graphene-supported
semiconductor quantum dots including CdSe and CdS
Main Wet Chemistry chemistry Seniors
Anduo
Wang
adw@temp
le.edu
CST CIS A Consistent SDN
Management Plane
with Logic Reasoning
My research interests center around improving networked-
systems with database techniques and formal methods. My
current research projects focus on software-defined
networks (SDN).
Main good math,
programming
with Python,
some
understanding
computer
science
seniors
Bo Ji boji@templ
e.edu
CST CIS Human behavior
recognition and
tracking
This project aims to develop human behavior recognition
and tracking systems using wireless sensing technologies
such as mmWave Radar.
Main Self-motivated;
hard-working;
Experienced in
Matlab; Basic
knowledge of
signal
processing and
machine
learning is
preferred but
not required.
CIS Junior or
senior
10/24/2019 33
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Bo Ji boji@templ
e.edu
CST CIS Quantum Machine
Learning
Students will investigate the design of Machine Learning
algorithms in the quantum domain that outperform (e.g.,
providing exponential or quadratic speedup) their classical
counterparts. Examples include solving linear system of
equations, principle component analysis, support vector
machine, reinforcement learning, etc.
Main Basic
knowledge of
machine
learning and
quantum
physics is
preferred but
not required.
CS or Math Junior &
Senior
Bo Ji boji@templ
e.edu
CST CIS Data freshness
optimization
Students will investigate the problem of optimizing data
freshness/timeliness in information-updating systems and
design efficient algorithms for the problem.
Main Basic
programming
experience in
Python or Java
or C++.
CS or Math Junior &
Senior
Bo Ji boji@templ
e.edu
CST CIS Knowledge-Defined
Networking
Students will work on applying machine learning
techniques to computer networks (e.g., resource allocation
and network operation). Further, using network theory
guided approach to enhance the developed solution.
Main Python
programming;
Matlab
programming;
basic
knowledge of
machine
CS or Math Junior &
Senior
Bo Ji boji@templ
e.edu
CST CIS Silent speech
recognition using
wireless sensing
This project aims to develop silent speech recognition and
human identification/authentication using wireless sensing
technologies such as mmWave Radar.
Main Self-motivated;
hard-working;
experienced in
Matlab;
basic
knowledge
about signal
processing and
CIS Junior or
senior
10/24/2019 34
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Chiu C. Tan cctan@tem
ple.edu
CST CIS Security of civilian-
captured videos
There is a rise in everyday people using their smartphones
to record potential criminal acts, e.g. people rioting,
violence in public spaces, and so on. Smartphones cameras
are not designed to provide evidence of wrongdoing. The
project will explore the potential security issues related to
civilian captured videos (e.g. potential for fake/tampered
videos) and possible solutions to address them.
Main General interest
in security.
Some familiarity
with video or
photo
manipulation
software like
Photoshop will
be preferred.
CIS, Math,
Physics
Sophomor
e, Juniors,
Seniors
Chiu C. Tan cctan@tem
ple.edu
CST CIS Wearable Computers
for Health Care
The project studies the use of wearable computing devices
to monitor
patients with dementia disorders. The goal is to develop
systems and
algorithms that can enable unobtrusive, long-term
monitoring of high
risk patients to improve early detection and measure
effectiveness of
treatment. The project is suitable for participants with
strong
prototyping skills.
Main Familiar with
Android
programming
and/or Web
programming
CIS/IST,
Math,
Sophomor
e, Junior,
Senior
Chiu C. Tan cctan@tem
ple.edu
CST CIS Reminder systems for
patients with cognitive
problems
Patients with cognitive problems sometimes have difficult
remembering to complete everyday tasks like taking
medication, consuming adequate fluids, and so on.
Reminder systems are systems that help these patients
keep track of these tasks. The project will involves studying
currently available systems and designing better
alternatives.
Main Students from
CS backgrounds
should be
comfortable
with Android
application
programming
and/or web
CIS, Pre
Med
Sophomor
e, Juniors,
Seniors
Eduard
Dragut
edragut@t
emple.edu
CST CIS Identifying Entity
Mentions in Social
Networking Streams
The project aims to develop methods that are capable to
recognize substrings in user messages that refer to an
entity (e.g., Phila or Philly refers to Philadelphia).
Main Good
programming
and analytic
skills. Ideally, a
student who
would like to
Math, CS,
ECE
Sophomor
e, Juniors,
Seniors
10/24/2019 35
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Eduard
Dragut
edragut@t
emple.edu
CST CIS Herveting User
Comments from the
Social Networking
Websites
This project aims to develop techniques that allow
automatic harvesting of user comments from microblogs
and other social networking websites. You will work with
Java, Javascript, JSON, MySQL, and other modern Web
programming tools.
Main Good
programming
and analytic
skills. Ideally, a
student who
would like to
pursue grad
studies.
Math, CS,
ECE
Sophomor
e, Juniors,
Seniors
Jamie
Payton
payton@te
mple.edu
CST CIS Pervasive Computing
Community Networks
to Increase Child
Indepdence
This project will build a pervasive computing technology
infrastructure and associated community connections to
increase social and mobile independence in children. The
project seeks to provide a balance between fine-grained
location tracking using wearable devices capable of sensing
and communication versus completely untethered,
untracked, "free-range kids". We address engagement and
retention of children to the system using gamification and
incentivization to promote physical and social
independence to achieve clearly stated health, social,
emotional, and educational goals. This project focuses
heavily on safety and privacy and on connecting those
Main some
programming
experience
ability to apply
math concepts
to solve
problems and
evaluate
solutions
Cs, ISST or
Math
Sophomor
e, Junior
or Senior
Jie Wu jiewu@tem
ple.edu
CST CIS WiFi and mobile phone
app
We focus on building a robust and accurate WiFi sensing
platform for various applications, such as activity
recognition and indoor localization. This project seeks to
largely reduce the training cost of current WiFi sensing
system with the help of transfer learning techniques.
Specifically, we will study what is the minimal number of
training instances needed to ensure good performance for
a new environment. In addition, we will investigate what
domain knowledge in exiting environment can be
transferred to new environments.
Main Strong
programming
skills (perferred
C and Matlab)
and signal
processing
experience
CIS, ECE Sophomor
e, Junior,
Senior
10/24/2019 36
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Jie Wu jiewu@tem
ple.edu
CST CIS Online Job Scheduling
with Machine Learning
Techniques
This project aims to develop an online job scheduler for
cloud/edge computing clusters using machine learning or
reinforcement learning techniques. Online job scheduler is
used to determine the priority and the amount of resource
allocated to each job in computing clusters, which is an
important but challenging problem. An efficient scheduler
could significantly reduce the average job finish time. In
the project, we would like to apply machine learning or
reinforcement learning techniques to solve the scheduling
problem.
Main Programming
experience in
Python or
Matlab; Basic
knowledge of
machine
learning
CIS/IST,
Math,
Sophomor
e, Junior,
Senior
Jie Wu jiewu@tem
ple.edu
CST CIS Network security and
forensic
This research focuses on a regular DDoS and transit-link
DDoS mitigation mechanism using a special type of router
called filter router. We are developing a model in which a
victim can protect itself and reduce useless congestion in
the network by sending filters to filter routers for blocking
attack traffic. In this research, the victim selects a subset of
filter routers optimally to minimize attack traffic and
blockage of legitimate users.
Main Basic
IP/Network
knowledge,
linux
shell/terminal,
Programming
languages
(C/C++/JAVA/Py
thon)
CIS/IST,
Math,
Sophomor
e, Junior,
Senior
Jie Wu jiewu@tem
ple.edu
CST CIS Datacenter and SDN This research focuses on efficiently and innovatively
leveraging SDN technology in a large-scale datacenter
network. SDN is essentially a way of making a network
programmable by decoupling control from the underlying
hardware and assigning it instead to a software-based
controller. With SDN, updating a policy or optimizing for
resource allocation in a datacenter is a matter of
programming the software, rather than buying a new
appliance or wrangling with a proprietary physical
interface. This project can have multiple interesting topics
of SDN in datacenters, including traffic engineering,
network updates, and resource allocation. Our computing
cluster has already installed a testbed of a datacenter
network, which is able to practically evaluate a lot of novel
research in the rising field of datacenter and SDN.
Main Self-motivated;
hard-working;
Experienced in
python; Basic
knowledge of
networking and
algorithms is
preferred but
not required.
CIS Juniors or
Seniors
10/24/2019 37
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Jie Wu jiewu@tem
ple.edu
CST CIS Blockchain and its
applications
Blockchain technology has been widely adopted, ranging
from cryptocurrency, financial services, Internet of Things
(IoT) to public and social services, while still at an early
stage of its development. Thus, lots of design details of this
technology need be perfected. In this project, students
may consider to modify existing consensus protocols to
improve Blockchain transaction throughput or propose
new transmission policy to decrease information
propagation delay in Blockchain networks, both of which
would improve the liveness of Blockchain.
Main Solid math
background
CS or Math Junior or
senior
Justin Y. Shi shi@templ
e.edu
CST CIS Digital Currency and
Distributed Computing
The lack of robust security in physical assets fostered the
research in distributed crypto systems like block-chains. It
has been shown that trust in distributed computing is a
better form of currency than the physical currencies.
However, while double-spending can be eliminated by the
use of block-chains, challenges still exist in preventing
Main Basic
knowledge of
programming
and
cryptographic
methods.
CIS, Physics,
Math,
Engineering -
CIS 2168
Juniors or
seniors
Krishna
Kant
kkant@tem
ple.edu
CST CIS Collaborative caching
in content centric
networks
The project will involve simulation study of a computer
network designed for distributing content such as
audio/video that is widely accessed and may have varying
levels of demands from different parts of the network. The
purpose of the simulation is to study various collaborative
Main The project
would need
good
programming
skills, exposure
CS Majors Junior or
Senior
Krishna
Kant
kkant@tem
ple.edu
CST CIS Building Magnetic
Communication Boards
The project concerns the development of circuit board and
protocol for electronic communication through magnetic
induction. The application of interest includes through the
body communications, and will require considerable effort
in enhancing the communications range. You will be
working closely with a Ph.D. student who is doing research
on this topic. The project will require familiarity with
basic background in electronics and digital circuits and
hands-on experience, including ability to program FPGAs
using Verilog or VHDL. Good programming abilities are a
must and familiarity with communications protocols is a
plus.
Main Good
programming
abilities are a
must and
familiarity with
communication
s protocols is a
plus.
CS Majors Junior or
Senior
10/24/2019 38
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Lognin Jan
Latecki
latecki@te
mple.edu
CST CIS Deep Neural Networks
and their Applications
One of the most innovative and transformative
technologies of our time is deep learning, a form of
machine learning that uses neural networks containing
many hidden layers, which are called deep neural networks
(DNNs). Recent success has led to breakthroughs in
applications in particular in computer vision. In this project,
we will focus in applying DNNs to various computer vision
tasks.
Main Programming
skills in Python
or C or Matlab.
CS, Math Sophomor
e, Junior
or Senior
Longin Jan
Latecki
latecki@te
mple.edu
CST CIS Deep Convolutional
Neural Networks for
Computer Vision
One of the most innovative and transformative
technologies of our time is deep learning, a form of
machine learning that uses neural networks containing
many hidden layers, which are called deep neural networks
(DNNs). The recent success of deep convolutional neural
networks (CNNs) has led to breakthroughs in applications
in particular in computer vision. In this project, we will
focus in applying CNNs to various computer vision tasks.
Main Linear Algebra.
Programming
skills.
Knowledge of
Python and
Matlab are a big
plus.
Computer
Science,
Math
Sophomor
e, Junior,
Senior
Pei Wang pei.wang@
temple.edu
CST CIS Testing an intelligent
reasoning system
NARS is an intelligent reasoning system that accepts
knowledge and problems in a formal language, and uses
some inference rules to derive new knowledge and to solve
the problems (see online publications and demo). This
system will be applied to various practical situations to test
the expressive power of the language and the inferential
power of the rules. Also under study will be the possibility
of using this logic to reason on structured knowledge
sources, such as databases and the Semantic Web.
Main Strong interest
in science,
especially in
human and
machine
intelligence;
solid
background in
mathematics
and computer
science. -
knowledge of
formal logic,
probability
theory, and
computer
programming
computer
and
information
sciences,
mathematic
s
Sophomor
e, Junior
or Senior
10/24/2019 39
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Qiang Zeng qzeng@te
mple.edu
CST CIS New security features
of the new Intel
processors
The latest generation of Intel processors provides new
security features, which may bring a revolution of systems
and software security. We will analyze such new features
and consider the fancy applications.
Main Interest in cyber
security. Good
programming
skills in C, C++,
Java or Python.
CIS Juniors or
Seniors
Qiang Zeng qzeng@te
mple.edu
CST CIS New security features
of the new Intel
processors
The latest generation of Intel processors provides new
security features, which may bring a revolution of systems
and software security. We will analyze such new features
and consider the fancy applications.
Main
Campus
Interest in cyber
security. Good
programming
skills in C, C++,
Java or Python.
CIS Juniors or
Seniors
Richard
Souvenir
souvenir@t
emple.edu
CST CIS Identifying Indoor
Scene Attributes from
Images
The student will apply and adapt recent techniques from
computer vision and machine learning to identify
attributes from images of indoor scenes. This work is part
of an ongoing project to (http://traffickcam.org/about) to
combat human trafficking by identifying hotel room
features from images.
Main Strong
programming
skills (preferably
Python),
interest or
experience in
image
CS
Richard
Souvenir
souvenir@t
emple.edu
CST CIS Identifying Indoor
Scene Attributes from
Images
The student will apply and adapt recent techniques from
computer vision and machine learning to identify
attributes from images of indoor scenes. This work is part
of an ongoing project to (http://traffickcam.org/about) to
combat human trafficking by identifying hotel room
features from images.
Main Strong
programming
skills (preferably
Python),
interest or
experience in
image
processing
Courses taken
CIS 3223 -
CS
10/24/2019 40
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Slobodan
Vucetic
vucetic@te
mple.edu
CST CIS Data Science Scientific and technological advances have allowed us to
collect massive amounts of diverse types of data. There is
an increasing recognition that data created by scientists,
mobile apps, internet, social media, crowdsourcing,
healthcare could be translated into valuable insights. A
data scientist is a person who has the skills, knowledge,
and ability to extract actionable knowledge from the data --
either for the good of society, advancement of science, or
profit in business. This project will be custom-made to suit
the background and interest of a student and give an
opportunity to get an expertise in all aspects of data
science including collecting, accessing, and processing large
and complex data, applying methods from machine
learning and statistics to analyze data, and presenting the
data and analytic insights through modern visualization
techniques.
Main Some
programming
experience,
good math
background -
Programming in
any language
(Python, Java, C,
Matlab)
Calculus 1
Any CST
major might
find this
project
valuable
10/24/2019 41
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Xiaojiang
Du
dux@templ
e.edu
CST CIS Mobile cloud
computing.
Mobile cloud computing is one of today's hottest new
technology markets. In mobile cloud computing, users
lease computing/storage services from cloud service
providers, and access the cloud from their mobile devices
(smart phones, tablets). Gartner (2011) predicts that
mobile cloud computing will reach a market value of
US$9.5 billion by 2014. Mobile cloud computing shares
with cloud computing the notion that some level of service
is provided by a cloud but accessed by mobile platforms.
Typical mobile cloud computing platforms include smart
phones and tablets. The most-used mobile operating
systems are UNIX variations such as Google Android and
Apple iOS. Tablets are larger than a smart phone but
interact with the user in a similar way, using a touch screen
as the primary input device. As of October 2011, the top-
selling tablets are the Apple iPad and Android tablets made
by Samsung, Motorola, and Acer.
Companies are being driven to the mobile cloud by
demand. Customers are demanding smart phone and
tablet applications so they can access key business
applications. Employees are demanding access to
Main Good
programming
skills - High
GPA -Solid math
background -
Good
communication
skills - Team
working skills
CS/IST/Math-
CS majors
Sophomor
e, Junior
or Senior
Xiaojiang
Du
dux@templ
e.edu
CST CIS Security and Privacy
Issues of Android
Phones/Tablets
In this project, the undergraduate student will work with
Dr. Du and his Ph.D. students on Security and Privacy Issues
of Android Phones/Tablets. First we will identify possible
attacks on Android Phones security and privacy. Second,
we will design effective security schemes to defend these
attacks. Third, we will implement the security schemes in
Main Good
programming
skills - Good
communication
skills
Team working
CS Sophomor
e, Junior
or Senior
Xiaojiang
Du
xjdu@temp
le.edu
CST CIS Internet of Things (IoT)
Security
Internet of things (IoT) have approached us in the last few
years. For example, Apple Inc. released its first smart watch
in April, 2015; Nest Labs (acquired by Google in 2014)
Main Good
programming
skills High GPA
CIS, Math
10/24/2019 42
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Zoran
Obradovic
zoran.obra
dovic@tem
ple.edu
CST CIS Predictive analytics in
big data
Predicting the system behaviors by analyzing big data.
Applications include social networks, medicine, climate and
environment.
Main Interdisciplinary
interests; Self-
motivation;
Problem solving
skills; Some
programming
experience in
any language -
the projects will
be tailored to
the students'
level of
preparation.
Computer
Science,
Statistics,
Physics,
Biology,
Chemistry,
Pharmacy,
Geology,
Environmen
tal Science
Alexandra
Davatzes
alix@templ
e.edu
CST EES Geochemical analysis
of a Paleoarchean
impact event.
Student will be completing a detailed geochemical analysis
of a section of rock collected from an impact boundary.
Main Completed
classes in
General
chemistry and
Geochemistry
or Petrology.
Skilled in Excel;
willing to work
hard. - Gen
Chem I, and
Geochemistry
or Petrology
Geology Juniors or
Seniors
Laura
Toran
ltoran@te
mple.edu
CST EES Stormwater
monitoring
Use data loggers, sampling, and other instruments to
understand how stormwater moves through and affects
urban ecosystems
Philadelp
hia
Comfortable
with field work
and with using
computers to
analyze data.
Geology,
Environmen
tal Science,
Physics
sophormo
re or
higher
10/24/2019 43
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Sujith Ravi sravi@tem
ple.edu
CST EES Opportunities for co-
location of solar
energy (PV) with
agriculture for cost
reductions and carbon,
water, and energy
footprint mitigation
Solar energy installations are rapidly increasing, due to
technological advances and policy support. Even though
solar energy provides several benefits such as reduction of
greenhouse gases, reclamation of degraded land, and
improving the quality of life in developing countries, the
deployment of large-scale renewable energy infrastructure
may negatively impact land and water resources. A major
challenge for the future is how to meet the ever-expanding
energy demand with limited land and water resources, in
the context of increasing demand for alternative uses such
as agricultural and domestic consumption. This project will
explore opportunities to co-locate solar infrastructures and
Main Experience in
data analysis
and data
visualization (in
R or Python) or
interest in
learning these
skills.
Environmen
tal Science,
Geology,
Biology
Sophomor
e & Junior
Sujith Ravi sravi@tem
ple.edu
CST EES Post-fire sediment
transport
Many drylands are undergoing changes in fire regimes and
increased fire frequency as a result of climate change and
human activities. Aeolian processes are considered to be a
significant but largely underestimated mechanism for the
removal and deposition of post-fire soil and nutrients
immediately following wildfires. Considering the
deleterious impact of airborne contaminants on air quality
Main Interest or
experience in
conducting
laboratory
soil/sediment
analysis using
ICP-OES and
Geology,
Environmen
tal Science,
Biology
Sophomor
e or Juniot
10/24/2019 44
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Sujith Ravi sravi@tem
ple.edu
CST EES Belowground
responses to climate
change: Root imaging
and analysis
Belowground processes such as root dynamics can alter
nutrient and water cycles and impact the response of
terrestrial ecosystems to changing climate and disturbance
regimes. Despite the relevance of belowground processes,
studies addressing the response of fine roots to changing
environmental conditions are rare, mostly due to the
difficulties in quantifying root dynamics (production,
growth and longevity) by non-destructive methods. This
project will investigate the belowground responses of
plants to simulated changes in climate, in particular
warming and droughts. We will analyze a time series of
below ground (root) images from a simulated climate
change experiment (combination of warming and drought),
collected using the unique minirhizotron root imaging
system. This technique will enable us to observe root
growth over time and trace single roots in the course of
their development. The methods involve computer-based
image analysis using the open source software application
– Rootfly – and statistical techniques for simultaneous
calculation of fine root production, length, mortality and
turnover.
Main interest in the
project/researc
h, critical
thinking,
quantitative
ability - Basic
statistics,
interest in
image
processing,
mostly
computer-
based project
Biology,
Computer
science,
Environmen
tal Sciences
Sophomor
e & Junior
10/24/2019 45
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Sujith Ravi sravi@tem
ple.edu
CST EES Belowground
responses to climate
change: Root imaging
and analysis
Belowground processes such as root dynamics can alter
nutrient and water cycles and impact the response of
terrestrial ecosystems to changing climate and disturbance
regimes. Despite the relevance of belowground processes,
studies addressing the response of fine roots to changing
environmental conditions are rare, mostly due to the
difficulties in quantifying root dynamics (production,
growth and longevity) by non-destructive methods. This
project will investigate the belowground responses of
plants to simulated changes in climate, in particular
warming and droughts. We will analyze a time series of
below ground (root) images from a simulated climate
change experiment (combination of warming and drought),
collected using the unique minirhizotron root imaging
system. This technique will enable us to observe root
growth over time and trace single roots in the course of
their development. The methods involve computer-based
image analysis using the open source software application
– Rootfly – and statistical techniques for simultaneous
Main interest in the
project/researc
h, critical
thinking,
quantitative
ability - Basic
statistics,
interest in
image
processing,
mostly
computer-
based project
Biology,
Computer
science,
Environmen
tal Sciences
Sujith Ravi sravi@tem
ple.edu
CST EES Impacts of biochar
application on soil
hydrologic properties
Novel carbon sequestration strategies such as large-scale
biochar application may provide sustainable pathways to
increase the terrestrial storage of carbon in agricultural
areas along with increasing crop production. Biochar has a
long residence time in the soil and hence the
environmental impacts of biochar addition needs to be
investigated to identify the tradeoffs and synergies. This
project will investigate the impacts of biochar application
on soil hydrologic properties. The undergraduate student
will assist in laboratory activities including soil sample
preparation, measuring soil hydrologic properties, data
management and visualization. Other duties may be
assigned.
Main Undergraduate
course in
Hydrology/soil
science, interest
in laboratory
experiments.
Environmen
tal Science
or Geology
Junior,
Senior
10/24/2019 46
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Ilya
Buynevich
coast@tem
ple.edu
CST EES/Geolog
y
Neoichnology: Imaging
of Animal Traces in
Coastal Sediments
Analysis of modern structures (casts) and georadar images
of several large organisms (crustaceans, reptiles) that
produce bioturbation structures (burrows, nests) in coastal
settings (beaches and dunes). The findings will have
implications to geomorphology,
sedimentology/stratigraphy, petroleum geology
(macroporosity), geoarchaeology, geoforensics, and
conservation (e.g., sea turtle nests).
Main Ability to work
both
independently
and as part of a
research team,
with a
possibility of
field data
collection.
Geology,
Environmen
tal Science,
Biology, Civil
Engineering
Sophomor
e, Junior
or Senior
Bojeong
Kim
bkim@tem
ple.edu
CST Geology Phytotoxicity of metal
oxide nanoparticles
Ecological toxicity of nano-sized materials hasn't been
thoroughly evaluated. Through this project, plant toxicity
of metal oxide nanoparticles will be systematically
examined.
Main I will train
students for
proper skills
that need for
the project. No
skills needed.
Geology,
Environmen
tal Science,
Chemistry,
Biology
Sophomor
e or
Higher
ILYA
BUYNEVICH
coast@tem
ple.edu
CST Geology Zoogeomorphology Analysis of impact of native and invasive species on
landforms (beaches, dunes, river banks), with the goal of
assessing their role in geomorphic cascades and identifying
relict analogs.
Main Ability to work
as part of a field
team, analysis
of aerial
photography
and satellite
images. This
project may
lead to a
research
publication in a
Geology,
Environmen
tal Science,
Ecology,
Zoology
Sophomor
e, Junior,
Senior
10/24/2019 47
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Benjamin
Seibold
seibold@te
mple.edu
CST Mathemati
cs
Understanding Traffic
Flow and Autonomous
Vehicles via Robotics,
Simulation, and
Visualization
This project focuses on developing better models and
planning platforms for traffic flow and connected and
automated vehicles. Possible research directions are: (a)
Construct and program robot vehicles to behave like
human drivers or automated vehicles. (b) Devise better
models for stop-and-go traffic waves using real traffic data.
(c) Visualize traffic waves in a virtual reality environment.
No specific course or technical background is required; but
the projects require a keen interest in mathematical
models, simulations, data, programming, and hardware (all
or some of the above). Students will work in the Center for
Computational Mathematics and Modeling.
Main Experience in
robotics, data
processing,
and/or
visualization
(particularly
Unity) is very
welcome.
Mathematic
s, Computer
Science,
Physics
Sophomor
e, Junior,
Senior
Benjamin
Seibold
seibold@te
mple.edu
CST Mathemati
cs
Real-Time Interactive
High-Performance
Computing with Virtual
Reality
The traditional paradigm of high-performance computing is
that computations are run on a parallel computer for some
time, and then the simulation results are visualized for a
human user afterwards. Students participating in this
project will help develop a new paradigm: to run a
computation on a virtual reality (VR) environment that
enables the user to be immersed in the simulated world
and to affect the simulation while it is running. The project
requires a keen interest in programming (particularly
Unity), using VR hardware, and mathematical modeling
and simulation. Students will work in the Center for
Computational Mathematics and Modeling.
Main
Campus
Good
programming
skills and firm
proficiency in
Calculus are
required.
Experience in
Unity, and
background in
differential
equations,
numerical
analysis, or
Mathematic
s, Computer
Science,
Physics
Sophomor
e, junior,
senior
Charles
Osborne
cosborne@
temple.edu
CST Mathemati
cs
The Collatz Conjecture The Collatz conjecture is a claim relating to a famous open
problem in number theory. The problem is simply stated
and accessible at the undergraduate level. It has been
studied
extensively by many leading number theorists, including
Paul Erd}os. Our work currently approaches the problem in
two directions. The first approach uses classical
mathematical methods to show that certain subsets of the
integers cannot contain the minimal counterexample to
the Collatz conjecture (if such a counterexample exists).
The second focuses on interpreting the graphs that arise
Main Reasoning and
Quantitative
ability, interest
in mathematics,
either
completion of a
3000 level
mathematics
course or
computer
programming
Mathematic
s, Computer
Science
Junior,
Senior
10/24/2019 48
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Daniel
Szyld
szyld@tem
ple.edu
CST Mathemati
cs
Bipartite matrices and
Perron Frobenius
property
This is an advance Linear Algebra project. If a matrix A is
nonnegative and irreducible and if r is its spectral radius, it
is known that -r is an eigenvalue if and only if the matrix is
bipartite, that is, its corresponding graph is bipartite (it has
two separate connected components). The goal of the
project is to explore similar properties when A is not
nonnegative.
Main Students should
have completed
the basic linear
algebra course,
and possibly the
second linear
algebra course.
Knowledge of
graph theory is
desirable. An
Mathematic
s or CIS
Sophomor
e, Junior,
Senior
Gillian
Queisser
gillian.queis
ser@templ
e.edu
CST Mathemati
cs
Grid generation and
convergence analysis
for the Poisson-Nernst-
Planck equations
The student researcher will work on developing automated
ways to generate grids for the numerical computation of
the Poisson-Nernst-Planck (PNP) equations. PNP equations
describe the behavior of charged particles under diffusive
and electrical fluxes. Using an established numerical
framework for solving the PNP equations this project will
focus on ways to automatically create test geometries
(grids) and to use these to investigate the convergence
behavior of different numerical solvers. The goal is to
streamline numerical testing and finding ideal numerical
solvers for the PNP equations.
Main Programming
skills (scripting
language
and/or object-
oriented
language) and
an interest in
applied
mathematics/n
umerics
Mathematic
s, Computer
Science
Juniors or
Seniors
Gillian
Queisser
gillian.queis
ser@templ
e.edu
CST Mathemati
cs
Simulating networks of
brain cells under
synapse loss
The student researcher will get to know novel simulation
tools to simulate neural networks and use these tools to
investigate the behavior of networks when connections
between cells, so called synapses, are lost. This effect is
common in diseases like Alzheimer's and identifying ways
for cells to compensate synapse loss is of great importance.
The focus of this project is to systematically simulate
network behavior under various neuro-degenerative
conditions with the goal of identifying cellular components
that can compensate synapse loss.
Main Programming
skills (scripting
language
and/or object-
oriented
language) are a
plus.
Mathematic
s, Computer
Science,
Biology
Juniors or
Seniors
10/24/2019 49
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Gillian
Queisser
gillian.queis
ser@templ
e.edu
CST Mathemati
cs
Vector graphic export
of two- and three-
dimensional scientific
data
The student researcher will develop export routines for
scientific data in two and three dimensions. The
visualization of scientific data is critical when conveying
new research results. The goal of this project is to develop
ways to export ugx-data (an xml-based scientific computing
file format) to vector graphics formats, such as svg. The
students results can be included in broadly used open-
source projects (uG4, NeuroBox and others).
Main Programming
skills (scripting
language
and/or object-
oriented
language)
Mathematic
s, Computer
Science
Juniors or
Seniors
Gillian
Queisser
gillian.queis
ser@templ
e.edu
CST Mathemati
cs
Modeling and
Simulation of Calcium
Dynamics in Healthy
and Diseased Neurons
In this project the student researcher will use novel
simulation tools to simulate and evaluate the dynamics of
calcium signals in neurons. Calcium is one of the most
important molecules in neuronal signaling and is implicated
in multiple ageing-related neurodegenerative diseases. The
project will focus on systematically simulating cell-calcium
dynamics under the influence of calcium regulating
parameter sets representing healthy and disease-state
neurons. The goal is to identify critical components in the
calcium signaling cascade towards and into the cell
nucleus, which eventually give rise to new insights into
ageing-related diseases.
Main Programming
skills (scripting
language
and/or object-
oriented
language) are a
plus.
Mathematic
s, Computer
Science,
Biology
Juniors or
Seniors
Gillian
Queisser
gillian.queis
ser@templ
e.edu
CST Mathemati
cs
3D printing -
optimizing printing
procedures
This project revolves around 3D printing, a technology that
is gradually turning into a main stream application.
However, scientific research of 3D printing algorithms
could significantly improve material consumption and
structural stability of printed objects. Students will study
3D printing infrastructure and analyze methods and
printing algorithms from a mathematical and
computational perspective. The project will be carried out
at the Center for Computational Mathematics and
Modeling.
Main Knowledge of
programing
languages is
beneficial, as
well as a strong
interest in
applying
mathematical
and algorithmic
concepts in a
hands on
research
project.
Math,
Computer
Science,
Physics
Sophomoe
, Juniors
or Seniors
10/24/2019 50
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Isaac
Klapper
klapper@te
mple.edu
CST Mathemati
cs
Modeling of biofilm-
host interactions
Biofilms are well protected microbial communities found
throughout the environment. In hosts (e.g., humans),
biofilms are frequently associated with both long-term
health and with chronic infections. Interactions between
these microbial communities and host immune systems are
important but poorly understood. Mathematical models
can provide a platform on which to test and generate new
hypotheses about these interactions.
Main Programming
skills are
helpful.
Any Sophomor
e or Junior
Shumo Cui shumo.cui
@temple.e
du
CST Mathemati
cs
Analyzing phantom
traffic jams
How annoying is it when traffic comes to an inexplicable
stop for no apparent reason before starting right back up?
In fact, besides the psychological consequence, those so-
called phantom traffic jams also contribute to increased
fuel consumption, vehicle emissions, accidents and delay.
Using the novel mathematical models and simulation tools,
we will investigate and analyze the interaction of phantom
traffic jams and their stability. The results of this research
will enable researchers to improve the ability of
mathematical models to describe the real traffic.
Main Good
programming
skills
Mathematic
s, Computer
Science
Junior,
Senior
Yury
Grabovsky
yury@temp
le.edu
CST Mathemati
cs
Computation of
rotationally invariant
Jordan multialgebras
with Maple
Effective properties of composite materials strongly
depend not only on the
composition, but also on the microstructure. However, in
some special
situations it is possible to derive formulas relating effective
properties of
the composite and properties of the constituent materials,
no matter what the
microstructure is. There is a general theory for identifying
all such special
situations, called "exact relations". Each exact relation can
be described in
terms of a nice algebraic object: a subspace of matrices,
which is closed with
respect to several special multiplications (different from
Main Interest in
theoretical
research. Strong
mathematical
background.
Strong
programming
skills. Grade A in
Theoretical
Linear Algebra
MATH 3051.
programming
skills. Grade A in
Theoretical
Linear Algebra
Mathematic
s
Juniors or
Seniors
10/24/2019 51
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Adrienn
Ruzsinszky
aruzsinszky
@temple.e
du
CST Physics Implementation and
application of
advanced electronic
structure methods
This project requires advanced programming skills either in
Python or Fortran. In our research group we are developing
approximations based on Density Functional
Theory/Nonlocal Many Body Theory that need to be
implemented in electronic structure codes. These
approximations require thorough testing on molecules and
solids. Within this project during the implementation,
students can learn about the strengths and limitations of
these methods along with acquiring practice in
computation.
Main advanced
programming
skills in Python
or Fortran,
some basic
knowledge in
Quantum
Mechanics
Physics/Che
mistry
Juniors or
Seniors
Adrienn
Ruzsinszky
aruzsinszky
@temple.e
du
Science
and
Technolo
gy
Physics Accurate electronic
structure of negatively-
charged water clusters
The hydrated electron, as the simplest reducing agent,
captures intense interest in the scientific community.
Anionic water clusters are relatively simple systems to
model hydrated electrons. These clusters are generally
considered to be extremely challenging for theoretical
models due to the diffuse nature of the excess electron
distribution.
The many-body GW approximation has become an
available tool to predict charged excitations in materials.
Within this project we aim to make a systematic
assessment of various GW-based methods for the
ionization energies and electron affinities of negatively
charged water clusters.
With these approaches we can not only gain more insight
into the role of the electron correlation in the binding of
the excess electron but the results can serve as
benchmarks for the scientific community.
Main
Campus
Serious interest
in
computational
work.
Responsibility
and motivation.
A basic
experience with
Linux platform.
Physics/Che
mistry
Junior,
Senior
10/24/2019 52
Fall 2019 CST Faculty Research ProjectsFaculty
Name
Address
Faculty
School or
College
Faculty
Departmen
t
Project title Project Description Project
Location
Important
selection
criteria
Student
Majors
Desired
Class
Preferenc
e
Adrienn
Ruzsinszky
aruzsinszky
@temple.e
du
School of
Science
and
Technolo
gy
Physics Accurate many-body
calculations of
negatively-charged
water clusters
The hydrated electron, as the simplest reducing agent,
captures high interest in the scientific community. Anionic
water clusters are relatively simple systems to model
hydrated electrons. These negative clusters are generally
considered to be extremely challenging for theoretical
models due to the diffuse nature of the excess electron
distribution.
The many-body GW approximation has become an
available tool to predict charged excitations in materials.
Within this project we aim to make a systematic
assessment of various GW-based methods for the
ionization energies and electron affinities of negatively
charged water clusters. With these approaches we can not
only gain more insight about the role of the electron
correlation in the binding of the excess electron, but the
results can serve as benchmarks for the scientific
community.
Main
Campus
I am expecting
hard-working
students with
an interest in
computational/t
heoretical work.
Students at
junior/senior
level are
welcome to
work with me
and one of my
graduate
students. Some
basic Linux
knowledge can
be useful.
Physics/Che
mistry
Junior,
Senior
Bernd
Surrow
surrow@te
mple.edu
CST Physics Automated Leakage
Current Measurements
This project requires a lot of hands-on lab time.
The student will develop a graphical user interface (GUI) via
MATLAB/LABVIEW that can interact with the measurement
devices, which supplies a voltage to a micropattern
detector and reads the resulting current. The GUI will then
be automated to record the voltage and current at a
specific frequency, and plotting the values as a function of
Main Physics or
Math
Sophomor
e, Junior,
Senior
C. J.
Martoff
martoff@te
mple.edu
CST Physics MOT Gradient Coil
Design for HUNTER
see website for description of experiment:
https://phys.cst.temple.edu/hunter/
The experiment requires a set (2 or 4) of magnet coils to
produce a magnetic field gradient needed to maintain the
laser atom trap. We have to design these coils-
mechanically, electrically, magnetically, thermally, using
freshman physics principles and sophisticated simulation
software.
Main Sophomor
e, Junior,
Senior
10/24/2019 53