Explore beyond the surface. - Cleveland Clinic€¦ · candidates for LASIK or PRK, and treatment of vision-threatening infections. Our surgeons recently began performing Descemet

CORNEA 2 GLAUCOMA 4 CATARACT 6 PERSPECTIVES 8

Ophthalmology UpdateCOLE EYE INSTITUTE | FALL 2014

Explore beyond the surface.Get practical news on topics that matter to you on our new physician blog.

WELCOME 1

Dear Colleagues

There is a remarkable piece of art at the Cleveland Clinic

called “Blue Berg” by artist Iñigo Manglano-Ovalle. It is a

30-foot suspended iceberg depicted in hundreds of tiny plastic

rods. This issue of Ophthalmology Update reminds me of

“Blue Berg.” Here is why. What you hold in your hands is only

the tip of the iceberg. There is much more great content

below the surface, on Cleveland Clinic’s new specialty blog for

medical professionals, Consult QD. Please visit ConsultQD —

Ophthalmology for even more great articles and perspectives

from the Cole Eye Institute and other thought leaders.

So beginning now, you can find additional content for your

practice at ConsultQD.org/oph, or simply use your smartphone

or tablet to scan the QR codes next to the articles you will

find inside this issue.

Sincerely,

Daniel F. Martin, MD Chairman, Cole Eye Institute

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Cole Eye Institute’s cornea service is among the nation’s top

academic and clinical services dedicated to treating diseases of

the cornea and anterior segment. Our institute was one of the first

centers to perform Descemet’s stripping automated endothelial

keratoplasty (DSAEK), a selective procedure for endothelial

diseases such as bullous keratopathy and Fuchs dystrophy that has

revolutionized corneal transplantation through greater safety, faster

visual recovery and more favorable refractive outcomes. Since

2005, nearly a thousand Cole Eye Institute patients have benefited

from technical advances in DSAEK pioneered by our surgeons.

Our team provides comprehensive care for corneal disease,

including complex corneal transplantation, advanced dry eye

treatment, refractive surgery options for patients who are not

candidates for LASIK or PRK, and treatment of vision-threatening

infections. Our surgeons recently began performing Descemet

membrane endothelial keratoplasty (DMEK), a more selective

procedure for endothelial dysfunction that may offer visual

advantages over DSAEK in certain patients. For a decade, our

cornea service has offered the Boston Keratoprosthesis for cases of

corneal blindness where traditional transplantation offers little hope,

and our commitment to serving these patients will be expanded this

fall with the addition of a dedicated ocular surface disease/high-risk

corneal transplant specialist.

One of our core missions is advancing science that drives the

next breakthroughs in therapy. Our team includes leading NIH-

funded investigators in corneal wound healing, corneal immunology

and infection, and corneal biomechanics and simulation-based

therapy. Our corneal surgeons have the world’s most extensive

experience in intraoperative OCT-guided surgery and are pioneering

the use of this exciting technology for enhancing intraoperative

visualization and patient outcomes. Access to clinical trials,

including a much-anticipated clinical trial of collagen crosslinking

for keratoconus, is a distinctive feature of our care model.

— William Dupps Jr., MD, PhD | Cole Eye Institute

2 Cleveland Clinic Cole Eye Institute

Comprehensive Cornea Care, Advancing Tomorrow’s Breakthroughs

C O R N E A

®

Excellent Result in Chronic Corneal Edema Case

Precise surgery accomplishes far more than palliation

A surgical procedure to relieve pain in an 85-year-old patient with

chronic corneal edema accomplished far more than palliation.

It also eliminated corneal neovascularization, and restored

epithelium and epithelial function, corneal clarity and visual

acuity. Learn more from Dr. Scott Wagenberg’s blog on

Consult QD.

Read more at: ConsultQD.org/Cornea3

Treating Advanced Dry Eye Exploring the range of available options

Dry eye is a multifactorial disease that causes tear deficiency,

excess evaporation, or both. Symptoms can be severe or disabling

discomfort, reduced visual acuity and marked staining on the

cornea and conjunctiva. To read about the best ways to treat dry

eye disease, visit Dr. Peter McGannon’s blog on Consult QD.


Visian ICL: An Alternative in Refractive Surgery

Risks of dormant virus rule out procedures using lasers

If your patient is not a candidate for LASIK and PRK, another

option may be just right for correcting his or her vision. If there’s

been no cataract surgery, the Visian ICL (implantable collamer

lens) can correct a wide range of myopia with up to 2.5 diopters

of astigmatism. To find out more, check out Dr. Michael Gressel’s

blog on Consult QD.


Tips for Managing Herpes Zoster Ophthalmicus

Up to half of cases manifest corneal complications

Short-term and more serious long-term complications can follow in

the wake of herpes zoster ophthalmicus (shingles). The cornea

may be affected in up to half of all cases. Get an overview from

Dr. Jeffrey Goshe of established and new preventive techniques and

management approaches for these complications.


CORNEA 3

CORNEA : Read more on the web by scanning the QR codes below or visiting ConsultQD.org/Cornea

®

We continue to see tremendous growth and opportunity for

glaucoma care at Cleveland Clinic’s Cole Eye Institute. In response,

we now have four full-time glaucoma specialists seeing patients at

our locations throughout Northeast Ohio. Last year alone, 17,949

patients were seen across Cole Eye Institute for a primary diagnosis

of glaucoma and 316 outpatient laser procedures for glaucoma

were performed.

To accommodate this patient volume, there have been

expansions and renovations at our regional locations. For example,

electronic medical records and images from our 12 Cirrus HD-OCT

machines and 12 visual field machines are immediately available at

any of our offices to allow easy coordination and continuance of care.

Cole Eye Institute remains a leader in providing high-quality

surgical glaucoma care. Although trabeculectomies and tube shunts

remain our most commonly performed procedures, we are offering

newer procedures such as iStent®, canaloplasty and endoscopic

cyclophotocoagulation, with iStent® implants increasing significantly

in 2014.

One of our greatest strengths is our ability to put together

multidisciplinary teams to provide the most effective care to our

glaucoma patients with complex disease states, such as bleb-related

endophthalmitis, steroid-induced glaucoma, glaucoma related to

genetic syndromes and severe ocular surface disease. Just a few

examples of our multidisciplinary surgical collaboration here at

Cole Eye Institute include simultaneous tube implant and PPV

(together with retina specialists), comanagement of complex uveitic

glaucoma (together with uvetis staff), simultaneous postoperative

management of glaucoma and amblyopia (together with pediatric

ophthalmology), and transscleral cyclophotocoagulation in

preparation for a keratoprosthesis (together with cornea service).

We are proud of the success we have had, and plan to build on that

success for 2014.

— Jonathan Eisengart, MD | Cole Eye Institute


Expanding to meet growing volume, new surgical offerings

GLAUCOMA

Case Study: Treating Primary Open-Angle Glaucoma

Handling complications after Ahmed tube placement

The Ahmed™ valve can effectively reduce intraocular pressure.

However, valve function on Ahmed tube shunts is not necessarily

guaranteed. Dr. Stella Paparizos’ case study on Consult QD on

treatment for open-angle glaucoma includes a discussion of the

best ways to proceed when valve failure is suspected.

Read more at: ConsultQD.org/Glaucoma3

Traditional vs. Minimally Invasive Glaucoma Surgery

Conventional care is still the gold standard procedure

Traditional glaucoma surgery is being challenged by the advent

of innovative techniques and new implants. However, minimally

invasive glaucoma surgeries (MIGS) lack a body of literature on

their efficacy and long-term outcomes. To find out more, see

Dr. Edward Rockwood’s Consult QD blog.


Case Studies: Cataract Surgery for Narrow-Angle Glaucoma Faster, lower-risk procedure also can lower IOP

Glaucoma has been successfully treated with cataract surgery.

Although it’s not right for everyone, it can be performed much

faster, with much lower risk, and a quicker recovery time

compared with traditional glaucoma surgery. To find out how

Dr. Jonathan Eisengart uses cataract surgery to treat glaucoma,

read his blog on Consult QD.


Challenges of Treating Childhood Glaucoma

Stakes are high; fast, effective action is essential

“The stakes are high in childhood glaucoma — sight or blindness

— and early diagnosis and treatment are imperative,” says Elias

Traboulsi, MD, ophthalmologist at Cleveland Clinic’s Cole Eye

Institute. To find out how he deals with the different types of

childhood glaucoma, read his blog on Consult QD.


GLAUCOMA 5

GLAUCOMA : Read more on the web by scanning the QR codes below or visiting ConsultQD.org/Glaucoma

Cataract surgery is among the world’s most commonly performed

surgical procedures. It’s also one of the most positive and rapidly

rewarding procedures for patients. Restoring an individual’s vision

and potentially correcting pre-existing visual deficits is equally

gratifying for eye surgeons. At Cleveland Clinic’s Cole Eye Institute,

we are innovators in performing, teaching and refining cataract

surgery to provide the best surgical outcomes — now and looking

toward the future.

Cole Eye Institute surgeons use the latest cataract surgery

technology. Besides the newest hardware, we have for two years

now been offering laser-assisted cataract surgery to patients

requesting premium services. Surgical astigmatism correction and

astigmatic and multifocal lens implants are available. As a tertiary

care referral center treating the most-severe eye conditions, we also

provide combination surgery, treating cataracts and other intraocular

pathology simultaneously. Surgical teams collaborate to save

patients additional surgery and speed visual recovery.

We have also taken a leadership role in providing surgical

training to residents. A surgery lab — with four fully equipped

surgical stations and a surgical simulator — and an extensive

curriculum were created to ensure they are better prepared for

patient care.

In no small way, our quality surgical outcomes are a credit to

Cole Eye Institute’s advanced imaging and ultrasound team. With

cataract patients increasingly having had previous refractive surgery,

contact lens wear or requesting premium cataract procedures, the

data for calculating lens implant powers is critical.

In the past year, 6,678 cataract operations were performed

across Cleveland Clinic, and outcomes are tracked and published

annually. Laser surgery outcomes are being added this year and

compare favorably with conventional procedures. Additionally, a

cataract surgery care path was recently published to help standardize

cataract management, maximize quality and control costs.

— Richard Gans, MD | Cole Eye Institute


Innovating and refining surgical techniques for optimal outcomes

CATARACT

Tips & Tidbits: Laser Cataract Surgery

A bladeless option that can also reduce astigmatism

Laser cataract technology is improving the precision of surgery,

but patients pay out of pocket and want the best possible

outcomes. To get the latest tips to use for patients before, during

and after laser cataract surgery, see Dr. Michael Millstein’s blog

on Consult QD.

Read more at: ConsultQD.org/Cataract3

Managing Complications of Flomax in Cataract Procedures

Strategies for maintaining dilation during surgery

Flomax and other alpha-blockers can cause complications during

cataract surgery, including intraoperative floppy iris syndrome

(IFIS). To find out how Dr. Wynne Morley manages these problems

in the operating room, read her blog post on Consult QD.


Avoiding Refractive Surprises in Cataract Surgery

Contact lenses, previous surgeries present challenges

Cataract patients who wear contact lenses or who’ve had previous

refractive surgery present special challenges in achieving targeted

outcomes. Knowing what these are and how to deal with them

can avoid refractive surprises. On Consult QD, Dr. Allen Roth

discusses how to find the best implant fit for these patients.


Case Study: MIGS Frees Patient From Eyedrops

MIGS offers a great option for some patients

You won’t find iStents® in the Apple iStore, but rather, among

ophthalmologists performing leading-edge glaucoma and cataract

surgery. Micro-invasive glaucoma surgery (MIGS) is a breakthrough

technology designed to be used with cataract surgery. To find out

more, see Dr. Anna Singh’s blog post on Consult QD.


CATARACT 7

CATARACT : Read more on the web by scanning the QR codes below or visiting ConsultQD.org/Cataract


Clinical Subspecialties Cornea Transplants: DSAEK Method Superior to PK

William Dupps Jr., MD, PhD Cleveland Clinic Cole Eye Institute cornea surgeon

Benefits include more rapid return of visual acuity

Contact lens-mediated Acanthamoeba Harms Vision

Jeffrey Goshe, MD

Cleveland Clinic Cole Eye Institute cornea specialist

Rare infection easily misdiagnosed, delaying treatment

Case Study: Advanced Diagnostics Help Resolve Microsporidial Keratitis


Electron microscopy leads to the resolution of a prolonged case of microsporidial keratitis

Expanding the Retinal Imaging Field with Ultra-Widefield Technology

Justis Ehlers, MD Cleveland Clinic Cole Eye Institute vitreoretinal surgeon

Enhanced retinal imaging technology can visualize up to a 200-degree retinal field in a single image.

Optimizing Dry Eyes for Refractive Surgery

Steven Wilson, MDCleveland Clinic Cole Eye Institute refractive surgeon

Manage condition before procedure for best results

Case Study: Enhancement 13 Years After Lasik


Today’s LASIK meets yesterday’s technology

Research & InnovationForging Next-Generation Integrated Intraoperative OCT Instrumentation


PIONEER study used to help identify the optimal applications for intraoperative OCT

Researchers Developing 3-D Patient-Specific Model of Corneal Properties


NIH-funded project could aid keratoconus detection, refractive surgical screening

Optical Coherence Tomography Gives New Insight Into Choroid

Peter Kaiser, MD Director of the Cleveland Clinic Cole Eye Institute Ophthalmic Imaging Center

Enhanced depth imaging helps with diagnosis, treatment

Strabismus Surgery in Thyroid Eye Disease

Elias Traboulsi, MD Cleveland Clinic Cole Eye Institute Head of Pediatric Ophthalmology

10-year data published on outcomes-improving technique

Blood Biomarkers to Guide Surveillance and Treatment of Uveal Melanoma Being Explored

Arun Singh, MD Cleveland Clinic Cole Eye Institute ophthalmic oncologist

New options being explored may one day improve outcomes

Visit our blog today to explore these additional perspectives

PERSPECTIVES 9

Electronic Medical RecordsElectronic Medical Records: The Future Is Now

Rishi Singh, MD Cleveland Clinic Cole Eye Institute vitreoretinal surgeon

Pros and cons for an ophthalmology practice

Imaging Solutions in the Age of EMR


Seamless display, storage, sharing of diagnostic data is vital

How Coordinated Care Benefits Uveitis Patients

Sunil Srivastava, MD Cleveland Clinic Cole Eye Institute vitreoretinal surgeon

Electronic medical records aid communication, treatment

Clear and Concise: EMR Technology Helps Nurses and Staff, Too

Tiffany Rodstrom, RN Cleveland Clinic Cole Eye Institute

Ophthalmic nurses, other staffers benefit too

Building a Better Tech Toolbox

Rishi Singh, MD Cleveland Clinic Cole Eye Institute vitreoretinal surgeon

Tailor essential features and functions to your needs

System Puts Ophthalmologists’ Electronic Medical Record Needs in Focus

Peter Kaiser, MD Director of the Cleveland Clinic Cole Eye Institute Ophthalmic Imaging Center

New Cleveland Clinic system benefits doctors, patients

Outside PerspectivesU.S. News and World Report addresses Ophthalmologists’ concerns about Rankings

Avery Comarow Health Rankings Editor U.S. News & World Report

Various misunderstandings concerning the Best Hospitals rankings addressed

Lessons Learned From Electronic Health Records (Video)

David Epley, MD Children’s Eye Care Kirkland, WA

Ophthalmologist discusses system’s cost, practice impact

Image Integration into EHR (Video)

Michael Boland, MD, PhD Director of Information Technology at Johns Hopkins Medical School’s Wilmer Eye Institute

Factors in getting ophthalmology systems to communicate

Cloud Or In-House Server For Practice Data? (Video)

Michael Boland, MD, PhD Director of Information Technology at Johns Hopkins Medical School’s Wilmer Eye Institute

Ophthalmic IT expert reviews EHR data storage options

Ophthalmologists Prepare Eye Disease Registry (Video)

Bill Rich, MD American Academy of Ophthalmology Medical Director of Health Policy

IRIS™ clinical database will track outcomes, quality

PERSPECTIVES : Read more on the web by scanning the QR codes below or visiting ConsultQD.org/oph

Retinal Diseases

A Prospective, Two-Cohort, Single-Masked Study to Evaluate the Effect of ESBA1008 Applied by Microvolume Injection or Infusion in Subjects with Exudative Age-Related Macular Degeneration

Objective: Demonstrate a treatment effect of ESBA1008 applied as microvolume injection or infusion on retinal function and morphology in subjects with exudative AMD.

Contact: Rishi Singh, MD, 216.445.9497, or Kathi Dastoli, RN, 216.445.5248

Ozurdex for Diabetic Macular Edema Treated with Pars Plana Vitrectomy and Membrane Removal (OPERA Study)

Objective: Examine the use of Ozurdex® (dexamethasone intravitreal implant) in patients who are undergoing pars plana vitrectomy for macular edema due to diabetic macular edema.

Contact: Sunil Srivastava, MD, 216.636.2286 or Kim Baynes, 216.444.2566

Safety and Efficacy of Intravitreal Ranibizumab for Diabetic Macular Edema Previously Treated with Intravitreal Bevacizumab: A Randomized Dual-Arm Comparative Dosing Trial (Phase: 1/2): REACT Study

Objective: Assess the ocular and systemic adverse events of ranibizumab for DME following previous treatment with intravitreal bevacizumab.

Contact: Justis Ehlers, MD, 216.636.0183, or Kathi Dastoli, RN, 216.445.5248

A Phase III, Randomized, Double- Masked, Controlled Trial To Establish The Safety And Efficacy of Intravitreous Administration of Fovista™ (Anti PDGF-B Pegylated Aptamer) Administered in Combination with Lucentis Compared to Lucentis Monotherapy in Subjects with Subfoveal Neovascular Age-Related Macular Degeneration

Objective: Evaluate the safety and efficacy of Fovista™ intravitreous administration.


Clinical TrialsThe following studies are either currently enrolling new patients or are pending approval by the Institutional Review Board

and should be enrolling shortly:

Randomized, Double-Masked, Vehicle Controlled, Clinical Evaluation to Assess the Safety and Efficacy of Nepafenac Ophthalmic Suspension, 0.3% for Improvement in Clinical Outcomes Among Diabetic Subjects Following Cataract Surgery

Objective: Demonstrate superiority of nepafenac ophthalmic suspension, 0.3% dosed once daily relative to nepafenac vehicle based upon clinical outcomes among diabetic subjects following cataract surgery.

Contact: Richard Gans, MD, 216.444.0848, or Kathi Dastoli, RN, 216.445.5248

Prevention of Macular Edema in Patients with Diabetic Retinopathy Undergoing Cataract Surgery

Objective: Determine the safety and efficacy of intravitreal aflibercept injection in patients with diabetic retinopathy in the prevention of macular edema following cataract surgery.


Prospective Intraoperative and Perioperative Ophthalmic Imaging with Optical Coherence Tomography (PIONEER Study)

Objective: Assess the feasibility and utility of intraoperative OCT and perioperative OCT in optimizing the management of surgical ophthalmic diseases.

Contact: Justis Ehlers, MD, 216.636.0183, or Jamie Reese, RN, 216.636.0183

Uveitis

A Randomized, Double-Masked, Placebo-Controlled Study of the Safety and Efficacy of Gevokizumab in the Treatment of Active Non-Infectious Intermediate, Posterior, or Pan-Uveitis (Eyeguard-A Study)

Objective: Demonstrate the superiority of gevokizumab compared to placebo in the treatment of subjects with active non-infectious intermediate, posterior or pan-uveitis. The safety of gevokizumab will also be assessed.

Contact: Careen Lowder, MD, 216.444.3642, or Laura Holody, 216.445.3762


A Randomized, Double-Masked, Placebo-Controlled Study of the Safety and Efficacy of Gevokizumab in the Treatment of Subjects with Non-infectious Intermediate, Posterior, or Pan-Uveitis Currently Controlled with Systemic Treatment (Eyeguard-C Study)

Objective: Demonstrate the superiority of gevokizumab compared to placebo in reducing the risk of recurrent uveitic disease in subjects with non-infectious intermediate, posterior or pan-uveitis currently controlled with systemic treatment. The safety of gevokizumab will also be assessed.


Open-Label, Safety and Tolerability Study of Suprachoiroidal Triamcinolone Acetonide via Microneedle in Subjects with Non-Infectious Uveitis

Objective: Evaluate the safety, tolerability and efficacy of an injection of triamcinolone acetonide (TA) into the SCS of human subjects using a microneedle.

Contact: Sunil Srivastava, MD, 216.636.2286 or Kim Baynes, 216.444.2566

A Phase III, Multinational, Multicenter, Randomized, Masked, Controlled, Safety and Efficacy Study of a Fluocinolone Acetonide Intravitreal (FAI) Insert in Subjects with Chronic Noninfectious Uveitis Affecting the Posterior Segment of the Eye. (PSV-FAI-001)

Objective: Evaluate the safety and efficacy of a FAI insert in the management of subjects with chronic noninfectious uveitis affecting the posterior segment of the eye.


Pediatric Eye Disease

Bilateral Lateral Rectus Recession versus Unilateral Recess-Resect for Intermittent Exotropia (IXT1)

Objective: Evaluate the effectiveness of bilateral lateral rectus muscle recession versus unilateral lateral rectus recession with medial rectus resection procedures for the treatment of strabismus.

Contact: Elias Traboulsi, MD, 216.444.4363, or Sue Crowe, RN, 216.445.3840

The Natural History of the Progression of Atrophy Secondary to Stargardt’s Disease: Prospective Observation

Objective: Assess the rate of progression of Stargardt’s disease by measuring the growth of macular atrophic lesions using fundus autofluorescence.

Contact: Elias Traboulsi, MD, 216.444.4363, or Meghan Marino, 216.445.7671

The Natural History of the Progression of Atrophy Secondary to Stargardt’s Disease: Retrospective Longitudinal Observational Study

Objective: Assess the rate of progression of Stargardt’s disease by measuring the growth of macular atrophic lesions using fundus imaging/ visual field loss.


Genetics

Molecular Genetics of Eye Diseases

Objective: Study the molecular genetics of ophthalmic disorders through the compilation of a collection of DNA, plasma and eye tissue samples from patients and from families with a broad range of eye diseases and malformations.


Genetics of Uveitis

Objective: Identify changes in genes that may lead to uveitis.

Contact: Sunil Srivastava, MD, 216.636.2286, or Kim Baynes, 216.444.2566

Cornea / Refractive Surgery

LASIK Flap Thickness and Visual Outcomes Using the WaveLight FS200 Femtosecond Laser

Objective: To evaluate the visual outcome, accuracy and predictability of LASIK Flap thickness using the new Wavelight® FS200 femtosecond laser and compare these results to those obtained using the IntraLase™ FS60 femtosecond laser.

Contact: William J. Dupps Jr., MD, PhD, 216.444.8158, or Laura Holody, 216.445.2264

Long Term Safety Follow-up For Subjects Previously Implanted with The Acrysof® Cachet™ Phakic Lens in Clinical Studies C-02-23, C-02-40, C-03-21 and C-05-57

Objective: Estimate the annualized endothelial cell loss rate (for up to 10 years following date of implantation) of subjects previously implanted with the L-series AcrySof® Cachet™ Phakic Lens from clinical studies.

Contact: William J. Dupps Jr., MD, PhD, 216.444.8158, or Laura Holody, 216.445.2264

The following studies have completed patient enrollment in the last year at Cole Eye Institute and are in follow-up:

Investigator Initiated Observational Study of Intravitreal Aflibercept Injection for Exudative Age-Related Macular Degeneration Previously Treated with Ranibizumab or Bevacizumab

CLINICAL TRIALS 11

Residency Graduates (June 2014)

Jedediah McClintic, MD — Vitreoretinal Surgery Fellowship, Wake Forest University Medical Center, Winston-Salem, N.C.

Stephen McNutt, MD — General Ophthalmology Staff, Cleveland Clinic Cole Eye Institute, Cleveland, Ohio

Karolinne Rocha, MD, PhD — Associate Professor, Medical University of South Carolina Storm Eye Institute, Charleston, S.C.

Georgios Trichonas, MD — Vitreoretinal Surgery Fellowship, UPMC, University of Pittsburgh, Pittsburgh, Pa.

Current Residents

Residents, 1st Year

Brandon Baartman, MD Daniel Feiler, MD Preethi Ganapathy, MD, PhD Vishal Parikh, MD

Residents, 2nd Year

Maria Choudhary, MD Joseph Griffith, MD Nathaniel Sears, MD Adam Weber, MD

Residents, 3rd Year

Katie Hallahan, MD Priyanka Kumar, MD Tal Rubinstein, MD Jack Shao, MD (Chief Resident)

Fellowship Graduates (June 2014)

John Au, MD — Cornea and Refractive Surgery, NVISION Laser Eye Centers, Newport Beach, Calif.

Viral Juthani, MD — Assistant Professor, Ophthalmology and Visual Sciences, Albert Einstein College of Medicine Montefiore Medical Center, Bronx, N.Y.

Training the Leaders of TomorrowResidency and fellowship training is considered a high priority at Cleveland Clinic Cole Eye Institute, and is led by

outstanding faculty in a leading-edge facility. Our programs are highly competitive and produce superbly trained clinical

and academic ophthalmologists. We congratulate our recent graduates, wishing them luck in their next steps, and

welcome our new residents and fellows to the program.

Mona Kaleem, MD — Glaucoma Assistant Professor, University of Maryland Department of Ophthalmology, Baltimore, Md.

Bryan Costin, MD — Ophthalmic Oculoplastic Surgery Staff, Cleveland Clinic Cole Eye Institute, Cleveland, Ohio

Carlos Medina, MD — Vitreoretinal Fellowship, University of Miami Bascom Palmer Eye Institute, Miami, Fla.

Melanie Schmitt, MD — Assistant Professor, University of Wisconsin Madison Department of Ophthalmology, Madison, Wisc.

Robert “Jack” Courtney, MD — Retina Surgeon, Colorado Retina Associates, Denver, Colo.

Miriam Englander, MD — Retina Surgeon, Ophthalmic Consultants of Boston, Boston, Ma.

Current Fellows

Cornea, External Disease & Refractive Surgery (2014-2015) Naveen Mysore, MD, PhD Surajit Saha, MD

Glaucoma (2014-2015) Qui Vu, MD

Ophthalmic Oculoplastic Surgery (2014-2016) Rao Chundury, MD, MBA

Ophthalmic Oncology (2014-2015) Hassan Abdul Aziz, MD

Vitreoretinal Surgery (2013-2015) Ashleigh Levison, MD Adiel Smith, MD

Vitreoretinal Surgery (2014-2016) Yasha Modi, MD Paula Pecen, MD

For more information about Cole Eye Institute residency and fellowship training, go to clevelandclinic.org/EyeTraining or contact Rose Zeitz at [email protected].


TRAINING LEADERS FOR TOMORROW 12


Cole Eye Institute Staff

Cole Eye Institute Leadership

Chairman, Cole Eye Institute Daniel F. Martin, MD 216.444.0430

Institute Vice Chairman Institute Quality Review Officer Andrew P. Schachat, MD 216.444.7963

Institute Chairman for Education Elias I. Traboulsi, MD 216.444.2030

Comprehensive Ophthalmology

Aimee Chappelow, MD 440.988.4040

John Costin, MD 440.988.4040

Richard E. Gans, MD, FACS 216.444.0848

Philip N. Goldberg, MD 216.831.0120

Michael Gressel, MD 440.988.4040

Mohinder Gupta, MD 419.289.6466

Shari Martyn, MD 216.831.0120

Peter McGannon, MD 216.529.5320

Stephen McNutt, MD 216.444.2020

Michael E. Millstein, MD 216.831.0120

Wynne Morley, MD 440.366.9444

Sheldon M. Oberfeld, MD 440.461.4733

Stella Paparizos, MD 440.988.4040

Allen S. Roth, MD 216.831.0120

David B. Sholiton, MD 216.831.0120

Scott A. Wagenberg, MD 440.461.4733

Cornea and External Disease

William J. Dupps Jr., MD, PhD 216.444.2020

Jeffrey M. Goshe, MD 216.444.0845

Peter McGannon, MD 440.529.5320

David M. Meisler, MD 216.444.8102

Wynne Morley, MD 440.366.9444

Sheldon M. Oberfeld, MD 440.461.4733


Scott A. Wagenberg, MD 440.461.4733

Steven E. Wilson, MD 216.444.5887

Glaucoma

Jonathan A. Eisengart, MD 216.445.9429

Edward J. Rockwood, MD 216.444.1995

Annapurna Singh, MD 216.444.2020

Shalini Sood-Mendiratta, MD 216.445.5277

Keratorefractive Surgery


Ronald R. Krueger, MD, MSE 216.444.8158

Michael E. Millstein, MD 216.831.0120


Steven E. Wilson, MD 216.444.5887

Neuro-Ophthalmology

Gregory S. Kosmorsky, DO 216.444.2855

Lisa D. Lystad, MD 216.445.2530

Oculoplastics and Orbital

Surgery

Bryan Costin, MD 440.695.4010

Mark Levine, MD 440.988.4040

Julian D. Perry, MD 216.444.3635

Ophthalmic Anesthesia

Marc A. Feldman, MD 216.444.9088

J. Victor Ryckman, MD 216.444.6330

Sara Spagnuolo, MD 216.444.6324

Ophthalmic Oncology

Arun D. Singh, MD 216.445.9479

Patient ReferralTo refer a patient to the Cole Eye Institute, please call our referring physician hotline at 855.REFER.123 (855.733.3712).

Ophthalmology Update, a publication of Cleveland Clinic’s Cole Eye Institute, provides information for ophthalmologists about leading-edge diagnostic and management techniques and current research.

Please direct any correspondence to:

[email protected] Institute Chairman Daniel F. Martin, MD

Managing Editor Ann Bakuniene-Milanowski

Art Director Chip Valleriano

Marketing Manager Bill Sattin, PhD

Marketing Associate Mary Anne Connor

Cole Eye Institute, one of 27 institutes at Cleveland Clinic, is one of the few dedicated, comprehensive eye institutes in the world. Our internationally recognized staff diagnoses and treats the entire spectrum of eye conditions, caring for more than 170,000 patients and performing more than 7,500 surgeries annually.

Cleveland Clinic is a nonprofit, multispecialty academic medical center consistently ranked among the top hospitals in America by U.S. News & World Report. Founded in 1921, it is dedicated to providing quality specialized care and includes an outpatient clinic, a hospital with more than 1,300 staffed beds, an education institute and a research institute.

Ophthalmology Update is written for physicians and should be relied on for medical education purposes only. It does not provide a complete overview of the topics covered and should not replace the independent judgment of a physician about the appropriateness or risks of a procedure for a given patient. Physicians who wish to share this information with patients need to make them aware of any risks or potential complications associated with any procedures.

© 2014 The Cleveland Clinic Foundation

Ophthalmic Research

Bela Anand-Apte, MBBS, PhD 216.445.9739

John W. Crabb, PhD 216.445.0425


Stephanie Hagstrom, PhD 216.445.4133

Joe G. Hollyfield, PhD 216.445.3252

Neal S. Peachey, PhD 216.445.1942

Brian Perkins, PhD 216.444.9683

Sujata Rao, PhD 216.636.3156

K.P. Connie Tam, PhD 216.445.7936

Yuankai Tao, PhD 216.445.3867

Pediatric Ophthalmology and

Adult Strabismus

Fatema Ghasia, MD 216.444.2020

Andreas Marcotty, MD 216.831.0120

Elias I. Traboulsi, MD 216.444.2030

Retina

Amy Babiuch, MD 440.366.9444

Ryan Deasy, MD 440.695.4010

Justis P. Ehlers, MD 216.636.0183

Peter K. Kaiser, MD 216.444.6702

Daniel F. Martin, MD 216.444.0430

Andrew P. Schachat, MD 216.444.7963

Jonathan E. Sears, MD 216.444.8157

Rishi P. Singh, MD 216.445.9497

Sunil K. Srivastava, MD 216.636.2286

Richard Wyszynski, MD 440.988.4040

Alex Yuan, MD, PhD 216.444.2020

Uveitis

Careen Y. Lowder, MD, PhD 216.444.3642

Sunil K. Srivastava, MD 216.636.2286

Cleveland Clinic Florida

Dean Mitchell, MD 877.463.2010

Geetha Vedula, MD 877.463.2010

COLE EYE STAFF 15

Ophthalmology Update

Distinguished Lecture Series

Publications

Journal Publications 2013 – 2014 (year to date)

154

Books and Book Chapters 2013 – 2014 (year to date)

23


Sept. 18, 2014

Advances in Glaucoma Surgery

Malik Y. Kahook, MD The Slater Family Endowed Chair in Ophthalmology Professor of Ophthalmology Chief, Glaucoma Service Department of Ophthalmology University of Colorado School of Medicine Aurora, Colo.

Oct. 16, 2014

Targeting Conventional Outflow: The Next Generation of Glaucoma Drugs

W. Daniel Stamer, PhD Professor of Ophthalmology Professor of Biomedical Engineering Duke University Durham, N.C.

Nov. 20, 2014

Cataract Surgery: The New Glaucoma Procedure?

Steven L. Mansberger, MD, MPH Vice-Chair, Director of Glaucoma Services Devers Eye Institute Portland, Ore.

Resources for Physicians

24/7 ReferralsReferring Physician Hotline

855.REFER.123 (855.733.3712)

Hospital Transfers

800.553.5056

On the Web at clevelandclinic.org/refer123

Stay connected with us on …

Twitter/YouTube/Facebook/LinkedIn

About Cleveland ClinicCleveland Clinic is an integrated healthcare delivery system with

local, national and international reach. At Cleveland Clinic, 2,800

physicians represent 120 medical specialties and subspecialties.

We are a main campus, 18 family health centers, eight community

hospitals, Cleveland Clinic Florida, the Cleveland Clinic Lou Ruvo

Center for Brain Health in Las Vegas, Cleveland Clinic Canada,

Sheikh Khalifa Medical City and Cleveland Clinic Abu Dhabi.

In 2014, Cleveland Clinic was ranked one of America’s top hospitals

in U.S. News & World Report’s annual “Best Hospitals” survey.

The survey ranks Cleveland Clinic among the nation’s top 10

hospitals in 13 specialty areas, and the top hospital in heart care

(for the 20th consecutive year) and urologic care.

Resources for PhysiciansReferring Physician Center and Hotline

Cleveland Clinic’s Referring Physician Center has established a

24/7 hotline — 855.REFER.123 (855.733.3712) — to streamline

access to our array of medical services. Contact the Referring

Physician Hotline for information on our clinical specialties and

services, to schedule and confirm patient appointments, for

assistance in resolving service-related issues, and to connect with

Cleveland Clinic specialists.

Physician Directory

View all Cleveland Clinic staff online at clevelandclinic.org/staff.

Track Your Patient’s Care Online

DrConnect is a secure online service providing real-time

information about the treatment your patient receives

at Cleveland Clinic. Establish a DrConnect account at

clevelandclinic.org/drconnect.

Critical Care Transport Worldwide

Cleveland Clinic’s critical care transport teams and fleet

of vehicles are available to serve patients across the globe.

• To arrange for a critical care transfer, call 216.448.7000 or

866.547.1467 (see clevelandclinic.org/criticalcaretransport).

• For STEMI (ST elevated myocardial infarction), acute stroke,

ICH (intracerebral hemorrhage), SAH (subarachnoid

hemorrhage) or aortic syndrome transfers, call

877.379.CODE (2633).

Outcomes Data

View clinical Outcomes books from all Cleveland Clinic

institutes at clevelandclinic.org/outcomes.

CME Opportunities: Live and Online

The Cleveland Clinic Center for Continuing Education’s website

offers convenient, complimentary learning opportunities. Visit

ccfcme.org to learn more and use Cleveland Clinic’s myCME portal

(available from the site) to manage your CME credits.

Executive Education

Cleveland Clinic has two education programs for healthcare

executive leaders — the Executive Visitors’ Program and the two-

week Samson Global Leadership Academy immersion program.

Visit clevelandclinic.org/executiveeducation.

Same-Day Appointments

Cleveland Clinic offers same-day appointments to help your

patients get the care they need, right away. Have your patients

call our same-day appointment line, 216.444.CARE (2273), or

800.223.CARE (2273).

ConsultQD Blog for Physicians

Discover the latest research insights, innovations, treatment trends

and more. Visit clevelandclinic.org/ConsultQD.

Cole Eye InstituteThe Cleveland Clinic Foundation9500 Euclid Avenue / AC311Cleveland, OH 44195

Cleveland Clinic is top-ranked in Ohio and No. 7 in the nation for ophthalmology care, according to U.S. News & World Report .

An open, online forum from Cleveland Clinic’s Cole Eye Institute. Impact your practice with a daily dose of insights and perspectives from us and other thought leaders. Download or use your QR code reader app to read the stories throughout this issue, or visit ConsultQD.org/oph.

13-EYE-614

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