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Examination Component Findings and what they may mean Mental status Cognitive impairment on the MMSE orMoCA may indicate cognitive impairment and/or dementia If visual hallucinations and dementia are present before or within a year on parkinsonism onset, then consider the diagnosis of dementia with Lewy Bodies (DLB) Depression , apathy and anxiety are common but not exclusive of PD Cranial nerves Impaired vertical eye movements would make one suspicious of progressive supranuclear palsy (PSP) Check for hyposmia-it is usually an early marker of PD. You can use the UPSIT i test Masked face is typical in PD PD patients may have a soft voice and /or mumbled or fast speech Motor Examinati on Asymmetric resting tremor with bradykinesia on one side is very typical of PD PD tremors may occur in the tongue, jaw, lower lip, hand, or in the leg/foot PD tremor worsens with distracting the patient with mental tasks, etc Cogwheel rigidity is typical of PD Many patients have drooling due to reduced spontaneous swallowing of saliva Diminished gesturing is common in PD Micrographia is typical of PD Sensory examination Impaired position sense in the toes may indicate that the patient has a sensory ataxia on top of PD gait problems Sensory examination is usually unremarkable Coordination Conduct a dexterity test. Ask

Examination Component for Parkinson

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Examination ComponentFindings and what they may mean

Mental status Cognitive impairment on theMMSEorMoCAmay indicatecognitive impairment and/or dementia If visual hallucinations anddementiaare present before or within a year on parkinsonism onset, then consider the diagnosis of dementia with Lewy Bodies (DLB) Depression, apathy and anxiety are common but not exclusive of PD

Cranial nerves Impaired vertical eye movements would make one suspicious of progressive supranuclear palsy (PSP) Check for hyposmia-it is usually an early marker of PD. You can use the UPSITitest Masked face is typical in PD PD patients may have a soft voice and /or mumbled or fast speech

MotorExamination Asymmetric restingtremorwithbradykinesiaon one side is very typical of PD PDtremorsmay occur in the tongue, jaw, lower lip, hand, or in the leg/foot PDtremorworsens with distracting the patient with mental tasks, etc Cogwheelrigidityis typical of PD Many patients have drooling due to reduced spontaneous swallowing of saliva Diminished gesturing is common in PD Micrographia is typical of PD

Sensory examination Impaired position sense in the toes may indicate that the patient has a sensory ataxia on top of PD gait problems Sensory examination is usually unremarkable

Coordination examination Conduct a dexterity test. Ask patient to finger tap. Finger taps should have not only amaintained speed over 10-15 seconds but a maintained amplitude as well; slowing of speed, decrement of amplitude, and pauses/arrests in finger and foot taps are consistent withbradykinesia Ataxia would make one concerned about the possibility of multiple system atrophy (MSA)

Deep tendon reflexes Asymmetry of reflexes and up going plantar responses (Babinski sign) may indicate prior strokes/brain infarcts and vascular parkinsonism; or an up going toe would be suggestive of MSA

Gait and balance Gait dysfunctionis frequently multifactorial, and not just related to parkinsonism Freezing of gaitis related to PD A PD patient may have difficulties in rising from the chair A PD patient may have difficulties in taking the first step A PD patient may have limitations in turning Reduced arm swing is common in PD Postural instabilityis common. It can be measured with the Pull Testi. PD patients may have problems maintaining their balance Timed Up and Go (TUG) testcan be helpful for evaluation

Other Check for skin changes-melanoma