Evidence for Spinal Interventions 2012

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    Evidence for Precision Diagnosis

    and Management of Spinal Painand Radicular Pain

    Dr Sanjeeva GuptaMD; DNB; FRC; F!PP; FFPMRC

    Consultant in Pain Management and naest"esia

    Bradford #eac"ing $ospitals N$S #rust

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    %utline of t"e #al&

    • '"at is Precision Diagnosis ( Management)

    • *um+ar Facet ,oint Pain

    • Sacroiliac ,oint Pain• *o-er *im+ Radicular Pain

    • Failed Bac& Surger. S.ndrome

    • Cervical /ial Pain• Cervicogenic $eadac"e

    • 0pper *im+ Radicular Pain

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    Location Location Location

    Diagnosis

    Diagnosis

    Diagnosis

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    Current diagnostic methods

    1. History

    2. Physical examination

    3. Imaging

    4. Blood tests

    5. er!e conduction studies

    "lide #rom Dr $ %ichardson

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    &'( o# )atients *ith )ersistent lo*

    +ac, )ain cannot +e diagnosed

    using the con!entional model

    "lide #rom Dr $ %ichardson

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    Precision diagnostic methods

     Principle:

    1. Inner!ated

    2. Bloc,ade - %elie# 

    3. "timulation Pain

    "lide #rom Dr $ %ichardson

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    euroanatomy o# the ")ine

    • /acet 0oints su))lied +y edian Branches o# Dorsal %ami

    • uter third o# nnulus /i+rosis richly inner!ated –  Branches o# the "inu!erte+ral er!es

     –  he rey %ami Communicantes

     –  Lum+ar 6entral %ami

    Bogdu, 7 et al. $ nat 18&19 132: 385;

    Bogdu, 7 ")ine 18&39 &:2&;283.

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    svn

    ST

    direct

    branches

    **1 disc1

    verte+ra

     ALL nerve plexus

    svn

    r. comm.

    ST

    PLL nerve plexus

    P**1 dura1

    disc1 verte+ra

    #ter roen $ et al. m , nat 2334; 2556 757839

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    ?here does +ac, )ain come #rom@

    1. /acet $oints

    2. Discs

    3. "acroiliac 0oint

    4. er!e root > dura

    5. 6erte+ral Body

    ;. Ligaments

    A. uscles

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    ?here does +ac, )ain come #rom@

    /acet $oint Pain

    21( 4'( in general

    )o)ulation

    1;( in )ost lum+ar

    surgery )atients /B""

    "ch*ar=er et al. Spine 1884  Ann

     Rheum Dis 1885

    Datta "7 et al. Pain Physician 2''89

    12: 43A4;'

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    /acet $oint Pain E!aluation

    • /acet $oint In0ections

    • edial Branch Bloc, 

    • /alse )ositi!e rate 3'( –  Datta "7 et al. Pain Physician 2''89 12: 43A4;'

    High on the FeyeG o# the F"cotty dogG

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    edian Branch Bloc, Diagnostic

    • Lum+ar medial +ranch +loc,s ha!e +een

    sho*n to ha!e +oth diagnostic and thera)eutic

    utility –  Datta "7 et al. Pain Physician 2''89 12:43A4;'.A4;'. –  "ehgal 7 et al. Pain Physician 2''A9 1':21322&.

     –  Hancoc, $7 et al. Eur ")ine $. 2''A ct91;1':15385'.

     –  %u+instein "7et al. Best Pract %es Clin %heumatol 2''&9 22:4A14&2.

     –  I"I". Lum+ar BB. In: Bogdu, 7 ed. Practice uidelines #or ")inal Diagnostic and reatment

    Procedures. "an/rancisco7 C: I"I"9 2''4:4A-;5.

     –  Cohen "P7et al. nesthesiology. 2'1' ug91132:3854'5. –  Cohen "P7 et al. ")ine $. 2''& ay$un9&3:48&5'4

     –    Bogdu, : he inner!ation o# the lum+ar s)ine. ")ine 18&39 &:2&;283

     –  "ch*ar=er C7 et al. ")ine 18849 18:1132113A

     –  "ch*ar=er C7 et al. nn %heum Dis 18859 54:1''1';

     –  Drey#uss P7 et al. ")ine 188A9 22:&858'2

     –  a)lan 7 et al. ")ine 188&9 23:1&4A1&52

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    hera)eutic E##ecti!eness o# Lum+ar7 horacic

    and Cer!ical edian Branch Bloc,s

    L": L 2''1 1 - 3 in0 - LJ"ara)in> LJ sara)in J steroid: L 2''& 3 - 4 in0

    C": L 2''& L> LJ "teroid

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    /acet $oint - %adio#reKuency Dener!ation

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    "ummary o# In!alid "tudies o# /acet $oint

    Dener!ation due to echnical /la*s

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    Laclaire et al "tudy

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    "ummary and utcomes o# 6alid

    "tudies o# /acet $oint Dener!ation

    • omBerme0o /7 et al. $ ")inal Disord ech. 2'11 )r9242:;8A5.• Do+rogo*s,i $7 et al. Pharmacol %e). 2''595A4:4A5&'.• "cho##erman $7 et al. E##ecti!eness o# re)eated %/D #or lum+ar #acet )ain.

    2''4 o! 192821:24A13.

    • ornic, C7 et al. Com)lications o# lum+ar #acet %/D. ")ine Phila Pa 18A;.

    2''4 $un 1592812:13524.

    LEE% HE EDI% P i Ph i i

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    LEE% HE EDI% Pain Physician

    itle: I %E"P"E

    CritiKuing the critiKues: the merican Pain "ociety guideline and

    the merican "ociety o# 

    Inter!entional Pain Physicians res)onse to it

    • "hort itle: CritiKuing the critiKue

    • Corres)onding uthor: "herdil ath

    • "ir7

    In the a+o!e letter to the editor7 %oger Chou im)lies that the results could +e +iased and concludes that7 I Kuote7

    “It is difficult to see how the Nath et al trial could be taken as reliable evidence that radiofrequenc denervation iseffective!"

    he reason #or this7 as Kuoted in the letter *as“because the sham control #roup $which had hi#her baseline scores% had #reater potential to e&perienceimprovement from baseline! here is a mista,e here as it *as the acti!e treatment grou) that had higher+aseline scores o# )ain7 ot the sham grou) as stated

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    eneralised Pain

    LEE% HE EDI% Pain Physician

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    lo+al Im)ro!ement

    LEE% HE EDI% Pain Physician

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    here are se!en systematic re!ie*s o#

    radio#reKuency dener!ation #or chronic LBP

    uthor conclusions:

    • Bos*ell 2''A: Me!idence #or )ain relie# *ith radio#reKuency neurotomy o# medial

    +ranch ner!es *as moderate to strong in cer!ical and lum+ar s)ine.N

    •Datta 2''8: Mle!el II2 e!idence #or radio#reKuency neurotomyN

    •uerts 2''1 Mmoderate e!idence that radio#reKuency lum+ar #acet dener!ation *as more

    e##ecti!e #or chronic lo* +ac, )ain than )lace+oN

    •anchi,anti 2''2 Mmoderate to strong e!idence #or radio#reKuency neurotomyN

    •iemisto 2''3 Mcon#licting shortterm e##ect on chronic lo* +ac, )ainN

    •Bos*ell 2''5 Mmoderate to strong e!idence #or radio#reKuency neurotomyN

    •"li)man 2''3 M the e!idence #or radio#reKuency dener!ation is Le!el III or moderate.N

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    International Lo* Bac, Pain uidelines

    • ICE C&&: htt):>>***.nice.org.u,>C&&

    Do not re#er #or radio#reKuency dener!ation

    • merican Pain "ociety Lo* +ac, )ain guideline

    • htt):>>***.am)ainsoc.org>li+rary>)d#>LBPE!id%e!.)d# 

    E!idence on e##icacy o# %/ dener!ation o# the B o# the

    )rimary dorsal ramus is di##icult to inter)ret

    •Euro)ean Lo* Bac, Pain uideline

    htt):>>***.+ac,)aineuro)e.org>*e+>#iles>?2Ouidelines.)d# 

    ?e cannot recommend %/ #acet dener!ation #or )atients

    *ith nons)eci#ic chronic lo* +ac, )ain

    http://www.nice.org.uk/CG88http://www.ampainsoc.org/library/pdf/LBPEvidRev.pdfhttp://www.backpaineurope.org/web/files/WG2_Guidelines.pdfhttp://www.backpaineurope.org/web/files/WG2_Guidelines.pdfhttp://www.backpaineurope.org/web/files/WG2_Guidelines.pdfhttp://www.backpaineurope.org/web/files/WG2_Guidelines.pdfhttp://www.backpaineurope.org/web/files/WG2_Guidelines.pdfhttp://www.ampainsoc.org/library/pdf/LBPEvidRev.pdfhttp://www.ampainsoc.org/library/pdf/LBPEvidRev.pdfhttp://www.nice.org.uk/CG88http://www.nice.org.uk/CG88http://www.nice.org.uk/CG88

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    International Lo* Bac, Pain uidelines• "IPP uideline Com)rehensi!e E!idenceBased uidelines #or

    Inter!entional echniKues in the anagement o# Chronic

    ")inalPain:

    htt):>>***.)ain)hysician0ournal.com>2''8>0uly>2''89129;88&'2.)d# 

    %ecommendation: Based on uyatt et alNs criteria7 #or lum+ar

    radio#reKuency neurotomy the recommendation is 1C>strong

    • merican "ociety o# naesthesiologists Practice uidelines #or

    Chronic Pain anagement

    htt):>>0ournals.l**.com>anesthesiology>/ulltext>2'1'>'4'''>Pract

    iceOuidelinesO#orOChronicOPainOanagementO.13.as)x• %/ o# the B ner!es to the /$ should +e )er#ormed #or LBP *hen

    )re!ious diagnostic or thera)eutic in0ections o# the 0oint or B ner!e

    ha!e )ro!ided tem)orary relie# Category 1 e!idence

    http://www.painphysicianjournal.com/2009/july/2009;12;699-802.pdfhttp://journals.lww.com/anesthesiology/Fulltext/2010/04000/Practice_Guidelines_for_Chronic_Pain_Management_.13.aspxhttp://journals.lww.com/anesthesiology/Fulltext/2010/04000/Practice_Guidelines_for_Chronic_Pain_Management_.13.aspxhttp://journals.lww.com/anesthesiology/Fulltext/2010/04000/Practice_Guidelines_for_Chronic_Pain_Management_.13.aspxhttp://journals.lww.com/anesthesiology/Fulltext/2010/04000/Practice_Guidelines_for_Chronic_Pain_Management_.13.aspxhttp://www.painphysicianjournal.com/2009/july/2009;12;699-802.pdf

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    Precision Diagnosis andanagement

    o# "acroiliac $oint "I$ Pain

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    ?here does +ac, )ain come #rom@"I$ Pain Pre!alence

    21A )atients *ith maximal

    )ain +elo* L5 e!aluated

     – natomic controlled neg =0t +loc,s and>ordual )ositi!e A5( relie# "I$ +loc,s)er#ormed

     – Pre!alence o# "I$ )ain *as 1'2'( 

    • "ch*ar=er7 ")ine7 2':317 18857 aigne7 ")ine 2171&&87 188;

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    "I$ )ain +elo* a L>" #usion

    Pre!alence

    • In A4 com+ined )atients *ith lo* +ac, )aina#ter lum+osacral #usion7 the "I$ *as the )ainsource in 32( as esta+lished +y single I "I$in0ections –  at=. $ ")inal Disorders 1;98;887 2''37 aigne. Euro

    ")ine $ 149;54;5&7 2''5

    • "I$ *as #ound to +e a source o# )ost#usion )ain in 32( o# )atients +y singleI +loc, 

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    "I$ %e#erral Qones

    • aximal "I$ )ain is +elo* L5 +ut can re#er

    into the entire lo*er extremity *ith 84(

    ha!ing +uttoc,7 4&( *ith thigh )ain and 2&(

    *ith lo*er leg )ain• "ch*ar=er. ")ine 18857 aigne. ")ine 188;7 Drey#uss. ")ine 188;7 "li)man. rch Phys

    ed %eha+il 2'''9&1:33433&

    • Based on dual +loc,s7 maximal )ain is +elo*

    L5 and in the +uttoc, 

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    "I$ Inter!entions

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    he medial 0oint lines are the margins o# the )osterior

    "I 0oint line arro*

    C t t di d

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    Contrast medium s)read

    along the "I 0oint line

    Dou+le eedle echniKue: n lternati!e ethod #or Per#orming

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    Dou+le eedle echniKue: n lternati!e ethod #or Per#orming

    Di##icult "I$ In0ections." u)ta. Pain Physician 2'119 14: 2&12&4

    Dou+le eedle echniKue: n lternati!e ethod #or Per#orming

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    Dou+le eedle echniKue: n lternati!e ethod #or Per#orming

    Di##icult "I$ In0ections.

    " u)ta. Pain Physician 2'119 14: 2&12&4n Dynamic /luorosco)y the needle is not in the "I$ line

    Dou+le eedle echniKue #or "acroiliac $oint In0ection

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    Dou+le eedle echniKue #or "acroiliac $oint In0ection" u)ta. Pain Physician 2'119 14: 2&12&4

    "econd eedle in Inserted into the e*ly Identi#ied $oint Line on

    Dynamic /luorosco)y

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    Dou+le eedle echniKue #or "acroiliac $oint In0ection" u)ta. Pain Physician 2'119 14: 2&12&4

    Contrast In0ected hrough the "econd eedle Identi#ies the "I$

    Dou+le eedle echniKue #or "acroiliac $oint In0ection

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    Dou+le eedle echniKue #or "acroiliac $oint In0ection" u)ta. Pain Physician 2'119 14: 2&12&4

    Contrast In0ected rough the /irst eedle @ 6ascular ")read

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    "I$ Inter!entions E!idence

    • ost ex)erts maintain lo*!olume intraarticular local anaesthetic in0ections to +e the

    only relia+le diagnostic modality to diagnose "I$

    )ain –  Cohen "P. "acroiliac 0oint )ain: a com)rehensi!e re!ie* o# anatomy7

    diagnosis7 and treatment. nesth nalg. 2''591'1:144' - 1453

     –  Drey#uss P7 Dreyer "$7 Cole 7 et al. "acroiliac 0oint )ain. $ m cad

    rtho) "urg. 2''4912:255 2;5

     –  Hansen HC7 cen=ieBro*n 7 Cohen "P7 et al. "acroiliac 0ointinter!entions: a systematic re!ie*. Pain Physician. 2''A91':1;5< &4.

    "I$ I t ti E id

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    "I$ Inter!entions E!idence

    • here is one dou+le +lind and & )ros)ecti!e o+ser!ational studies

    *hich conclude that /luorosco)y > C > %I guided "I$ in0ectiono# steroid )ro!ides good short to intermediate term )ain relie# 3

    to ; months –  augars

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    "I$ %adio#reKuency E!idence

    • 2 %C and 3 Pros)ecti!e o+ser!ational studies in#orm

    that 5'( )atients o+tain 5'( )ain relie# *ith

    im)ro!ed #unction #or ; months #ollo*ing "I$ %/D in

    care#ully selected )atients #ollo*ing diagnostic in0ection

    o# local anaesthetic into the "I$

     –  " P. Cohen7 et .al. %andomi=ed Place+ocontrolled "tudy E!aluating Lateral Branch %/D #or

    "I$ Pain. nesthesiology 2''&9 1'8:2A8-&&

     –  Patel7 et al. %andomi=ed7 Place+o Controlled "tudy to ssess the E##icacy o# Lateral

    Branch Dener!ation #or Chronic "I$ Pain. Presented at the "IPP nnual eeting $une 2'11 –  " P. Cohen7 et al. utcome Predictors #or "acroiliac $oint Lateral Branch%adio#reKuency

    Dener!ation. %eg nesth Pain ed 2''89 34: 2'; - 214

     –  H araman7 et al. cta eurochir 2'11. Pu+lished online )ril 2'113

     –  Bui0s E$7 et al. Pain Clinic 2''49 1;: 13814;.

     –  e!arge= 7 et al. Eur %adiol 2''29 12: 13;'13;5

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    lancinating1 s"ooting1 or

    :electric pain; traveling

    do-n t"e lim+ in a

    narro- +and<

    RD!C0*R P!N

    Presentation can

    alter if treated

    Bogdu& N1 Govind ,< Medical Management of cute *um+ar Radicular Pain< n Evidence8Basedpproac"< Ne-castle6 Ne-castle Bone and ,oint !nstitute1 2333

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    echanism - I/LI

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    spinal nerve

    dorsal root

    ganglion

    RD!C0*R P!N

    N%

    P*7 P*E7

    #NF 

    interleu&ins 51 27

    metalloproteinases

    !g M1 !g G

    !NF*MM#!%N

    leu&otriene B=

    t"rom+a/ane

    interferon

    macrop"ages

    l.mp"oc.tes

    fi+ro+lasts

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    spinal nerve

    dorsal root

    ganglion

    RD!C0*R P!N

    N%

    P*7 P*E7

    #NF 

    interleu&ins 51 27

    metalloproteinases

    !g M1 !g G

    !NF*MM#!%N

    leu&otriene B=

    t"rom+a/ane

    interferon

    macrop"ages

    l.mp"oc.tes

    fi+ro+lasts

    S#ER%!DS

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    %adicular Pain

    • E)idurals - Caudal7 Interlaminar7

    rans#oramenal

    • Catheter euro)lasty

    • ")inal endosco)y

    • ")inal cord stimulator

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    Caudal E)idural "teroid In0ection #or

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    Caudal E)idural "teroid In0ection #or

    Lum+ar disc herniation>radiculitis

    Dash#ield - "ingle )rocedure

    L - L>LJ"teroid9 !erage )rocedure 3 to 4>year *ith 5'( )ain relie# and 4'( im)ro!ement o# DI o# 3;>5"igni#icant decrease in o)ioid inta,e and em)loyment status 12>52 )er )rocedure

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    Caudal E)idural "teroid In0ection

    LBP o# Post "urgery "yndrome

    L and %e!el - Post lum+ar laminectomy syndrome9 L DB eKui!alence trial9 L or L J Betamethasone9

    !erage )rocedure 3 to 4>year9 5'( )ain relie# and 4'( im)ro!ement o# DI o# 3544>52

    "igni#icant decrease in o)ioid inta,e 1'14>52 )er )rocedure

     

    Hesla - herniated disc o)erated

    L + I t l i E id l "t id I 0 ti

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    Lum+ar Interlaminar E)idural "teroid In0ection

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    "ummary - Lum+ar E"I

    •15 %CNs: & )ositi!e and A negati!e

     –  %adicular )ain relie# +et*een ; *,s 3 mths• o #luorosco)y• In the )osterior e)idural s)ace

    • @dhesions

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    rans#oraminal E)idural

    %andomised rials o# E##ecti!eness o#

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    %andomised rials o# E##ecti!eness o#

    rans#oramenal E)idural In0ection

    hahreman 7 /erch %7 Bogdu, . Pain edicne 2'1'9 11: 114811;&

    hahreman 7 Bogdu, . Pain ed. 2'11 $un912;:&A18.

    Le#t L4>5 rans#oraminal In0ection

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     Le#t L4>5 rans#oraminal In0ection

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    i $ t l " i 2''1 23 25&A

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    ar))inen $7 et al. ")ine 2''19 23: 25&A

    85

    • Cost e##ecti!eness o# /E"I #or sciatica

    • /or contained herniations

     – "teroid +etter #or leg )ain7 disa+ility7 "L% in the short

    term

     – By 1 year steroid )re!ented o)erations costing

    R127;;; less )er res)onder

    • /or extrusions – "teroid seemed to increase the o). rate and *as more

    ex)ensi!e

    %ie* D7 et al: Pros)ecti!e %C Dou+le Blind rial 

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    7 )he main outcome measure *as a!oidance o# surgery

    Bu)i!acaine and

    Betamethasone

    Bu)a!acaine only

    otal Patients 2& 2A

    Patients notha!ing surgery 2' A1(

    P S '.'''4

    8 33(

    Normall. all -ould "ave +een treated operativel.

    #reatment algorit"m no- includes > to = #FES! +efore considering surger.

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    # i l L l th ti I 0 ti

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    rans#oraminal Local naesthetic In0ection

    # i l "t id I 0 ti

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    rans#oraminal "teroid In0ection

    Change in Tse o# Health Care #rom +e#ore to a#ter treatment

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    Change in Tse o# Health Care #rom +e#ore to a#ter treatment

    Degree o# Pain %elie# in the 5 di##erent rou)s

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    Degree o# Pain %elie# in the 5 di##erent rou)s

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    /E"I "ystematic %e!ie*s

    • DePalma $7 et al. rch Phys ed %eha+il. 2''59&;A:14AA&3 –  he e!idence #or /E"Is re!eals le!el III moderate e!idence in su))ort o#

    these minimally in!asi!e and sa#e )rocedures in treating )ain#ul lum+ar

    radicular sym)toms. Current studies su))ort use o# /E"Is as a sa#e and

    minimally in!asi!e ad0unct treatment #or lum+ar radicular sym)toms.

    • +di "7 et al. Pain Physician. 2''A $an91'1:1&5212.

     –  he e!idence #or cer!ical and lum+ar /E"I is moderate #or longterm

    im)ro!ement in managing ner!e root )ain.

    • %o+erts "7 et al. P %. 2''8 $ul91A:;5A;&.

     –  here is #air e!idence su))orting /E"Is as su)erior to )lace+o #or treatingradicular sym)toms.

     –  here is good e!idence that /E"Is should +e used as a surgerys)aring

    inter!ention

     –  /E"Is are su)erior to interlaminar E"Is ILE"Is and caudal E"Is #or

    radicular )ain in )atients *ith su+acute or chronic radicular sym)toms.

    /E"I "ystematic %e!ie*s

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    67/100

    /E"I "ystematic %e!ie*s

    • Buena!entura %7 et al. Pain Physician. 2''8 $an/e+9121:23351

     –  he indicated e!idence #or /E"I is Le!el II1 #or shortterm relie# and

    Le!el II2 #or longterm im)ro!ement in the management o# lum+ar ner!e

    root and lo* +ac, )ain

    • anchi,anti L7 et al. Pain Physician. 2''89124:E1238&. –  Based on uyatt et alNs criteria7 the recommendation #or lum+ar /E"I is

    1C>strong in managing chronic lo* +ac, and lo*er extremity )ain

    • Benny B7 et al. $ Bac, usculos,elet %eha+il. 2'11 $an

    19242:;AA; –  here *as strong e!idence #or /E"I in the treatment o# lum+osacral

    radicular )ain #or +oth short term and long term relie# 

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  • 8/17/2019 Evidence for Spinal Interventions 2012

    69/100

  • 8/17/2019 Evidence for Spinal Interventions 2012

    70/100

  • 8/17/2019 Evidence for Spinal Interventions 2012

    71/100

    ur %es)onse

    Care#ul )atient selection7 #luorosco)y and contrast

    in0ection are needed #or e##ecti!e s)inal in0ections.

    on7 2'11'82; 11:58

    htt):>>***.+m0.com>content>343>+m0.d52A&@ta+res)onses

    http://www.bmj.com/content/343/bmj.d5278?tab=responseshttp://www.bmj.com/content/343/bmj.d5278?tab=responseshttp://www.bmj.com/content/343/bmj.d5278?tab=responses

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    euromodulation

     – ICE echnology a))raisal guidance 158

    • %ecommended #or chronic )ain o# neuro)athic

    origin

    • /ailed Bac, "urgery "yndrome

    • Com)lex %egional Pain "yndrome

  • 8/17/2019 Evidence for Spinal Interventions 2012

    73/100

    Cervical Spinal Pain and 0pper

    *im+ Radicular Pain Spinal

    • Diagnosis anagement o# ec, Pain

    • Diagnosis and anagement o# %adicular Pain

    ?here does the Pain Come /rom@

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    74/100

    ?here does the Pain Come /rom@

    • /acet $oints

    • Inter!erte+ral Discs

    •Ligaments

    • Dura mater

    • er!e %oot7 D%

    • Bone –  In#ection7 rauma7 umour

    • uscles

    Discs: roen. m $ nat 188'9 &&:2&28;

     Bogdu,. ")ine 18&&913:2&

     endal. ")ine 18829 1A:13235

    /acet $oints: Bogdu,. ")ine 18&29 A:3183'

    C i > i i

  • 8/17/2019 Evidence for Spinal Interventions 2012

    75/100

    Cer!ical > ec, Pain Incidence

    • Lo*er Cer!ical /acet $oint PainC4>5 to C;>A

     –  +out 5'( *ith nec, )ain•  Spine )11,2 ).:.--3-.2 Spine )1142 ,):).5.3-+2 Spine )11+2 ,*: ,*3,4 

     –  High s)eed 6 - &&(  6 of 7usculoskeletal Pain ,***2 0: 0.31+

    • T))er Cer!ical /$ Pain Cer!icogenic Headache C'>1 to C3>4

     –  53( #rom C23 0oint  6 Neurol Neurosur# Pschiatr )11-2 +.: ))0.31*

    $istor. and Clinical E/amination6 Cervical Somatic Referred Pain

    •Facet ,oint Pain

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    76/100

    C?89

    C>8=

    C78>

    C=8?

    C98@

    •Facet ,oint Pain

    •Discogenic Pain

    D-.er et al< Spine 2334; 2?6=?>8=?@ Gru++ and Aell.< Spine 7444; 7?62>5782>53

    C5; #acet 0oint most commonly

    in!ol!ed #ollo*ed +y C;A

    ne can localise to *ithin

    J> one 0oint on the +asis

     o# re#erral ma)s

  • 8/17/2019 Evidence for Spinal Interventions 2012

    77/100

    C>

    C=

    C?

    C9

    ap

    /luorosco)ic natomy

    Centroid o# the articular )illar

    C2 C2

    C4

    C5

    /alse Positi!e Bloc,s

  • 8/17/2019 Evidence for Spinal Interventions 2012

    78/100

    /alse Positi!e Bloc,s

    • !erage #alse )ositi!e rate o# single +loc,

    *as 48( range 2A to ;3( –  Barnsley et al. he Clinical $ournal o# Pain 18839 8:12413'

     –  anchi,anti et al. Pain Pract 2''&9 &:51'

     –  anchu,onda %7 et al. $ ")inal Disord ech 2''A9 2': 53845

    edian Branch eurotomy E!idence

  • 8/17/2019 Evidence for Spinal Interventions 2012

    79/100

    edian Branch eurotomy E!idence 

    Lord "7 Bogdu, 7 et al. %adio#reKuency eurotomy #or ChronicQyga)o)hyseal

    $oint Pain. he e* England $ournal o# edicine 188;9 335:1A211A2;

    • %andomised dou+le+lind trail

    • 24 )atients #ollo*ing 6• "ource o# )ain identi#ied +y dou+le+lind )lace+o

    controlled L +loc,s "aline7 lignocaine7 Bu)i!acaine

    • 12 )atients recei!ed %/ neurotomy C3>4 to C;>A• edian time +e#ore )ain returned to 5'( o# the

    )reo)erati!e le!el *as 2;3 days in the acti!e

    treatment grou) and & days in the control grou)

    edian Branch eurotomy E!idence

  • 8/17/2019 Evidence for Spinal Interventions 2012

    80/100

    edian Branch eurotomy E!idence 

    cDonald $7 Lord "7 Bogdu, . Long term #ollo*u) o# )atients treated *ith

    cer!ical radio#reKuency neurotomy #or chronic nec, )ain. eurosurgery 1888945: ;1;&

    • 2& )atients treated - 1& ;4( had com)lete )ain

    relie# #or a median )eriod o# 421 days

    • I# )ain recurred com)lete )ain relie# reinstated

    +y re)eat %/ neurotomy *ith some )atients

    ha!ing 4 to ; success#ul re)etitions

    "a)ir D et al. %/ B neurotomy in litigant and nonlitigant

    )atients *ith cer!ical *hi)lash. ")ine 2''19 2;: E2;&E2A3

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    81/100

    edian Branch eurotomy E!idence 

    Cer!icogenic Headache

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    82/100

    hird cci)ital er!e

    • C23 $oint is the source o# Cer!icogenic Headache in

    54( o# )atients

    • C3: three )oints reKuired7 to co!er !ariants in

    location• longitudinal +isector C23 =yga)o)hysial 0oint

     –  High o))osite a)ex o# C3 "P

     –  Lo* o))osite +ase o# C23 #oramen –  mid mid*ay +et*een

  • 8/17/2019 Evidence for Spinal Interventions 2012

    83/100

    B

    longitudinal bisector longitudinal bisector  high, mid, and low pointshigh, mid, and low points

    TARGT P!"#TS $!R T%"R& !''"P"TAL #R(TARGT P!"#TS $!R T%"R& !''"P"TAL #R(

    - E!idence

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    84/100

    o!ind $7 Bogdu, 7 et al. %adio#reKuency neurotomy #or the

    treatment o# third occi)ital headache. $ eurol eurosurg Psychiat

    2''39 A4: &&83

    • &;( o# 48 )atients o+tained com)lete )ain

    relie#7 the median duration o# )ain relie# *as28A days

    • 14 )atients had re)eat %/ neurotomy *hen

    their )ain recurred and 12 &;( regained

    com)lete )ain relie# 

  • 8/17/2019 Evidence for Spinal Interventions 2012

    85/100

    Cer!ical Pain lgorithm

    Cer!ical > ec, Pain

  • 8/17/2019 Evidence for Spinal Interventions 2012

    86/100

    Cer!ical > ec, Pain/acet 0oints

    • Headache Dominant "ym)tom- T))er cer!ical #acets

    • Headache ot Dominant - iddle and Lo*er Cer!ical

    /acets

    D-.er et al< Spine 2334; 2?6=?>8=?@

    C78>

    C=8?

    C98@

    C>8=

    C?89

    Cer!ical > ec, Pain lgorithm

  • 8/17/2019 Evidence for Spinal Interventions 2012

    87/100

    Cer!ical > ec, Pain lgorithm

      Cer!ical Pain

    @T))er Lim+ Pain Cer!ical xial Pain

    o T))er Lim+ %adicular Pain

    @Cer!ical %adicular Pain

    5'&'( ha!e nec, )ain

  • 8/17/2019 Evidence for Spinal Interventions 2012

    88/100

    Cer!ical /acet $oint Pain lgorithm

    "elect ost Li,ely $oint /rom Pain a)s  Per#orm /irst Bloc, C5; common

      8'( Pain %elie# C;A7 C457 CA1

  • 8/17/2019 Evidence for Spinal Interventions 2012

    89/100

    Cer!icogenic Headache lgorithm

    Per#orm C23 $oint Bloc, 54(

    ood Pain %elie# o Pain %elie#-C34 +loc, 

    echnically deKuate@

    Can C12 +loc, +e done sa#ely

    Per#orm Con#irmatory Bloc, echnically deKuate@

  • 8/17/2019 Evidence for Spinal Interventions 2012

    90/100

    Does the )ain satis#y the de#inition o# Cer!ical %adicular Pain

    o

  • 8/17/2019 Evidence for Spinal Interventions 2012

    91/100

    Cer!ical Interlaminar E)idural "teroid In0ections

    l*ays +elo* C; le!el

    Ideally CA1 le!el or +elo*

    T))er Lim+ %adicular Pain

    C i l E id l "t id I 0 ti

  • 8/17/2019 Evidence for Spinal Interventions 2012

    92/100

    Cer!ical E)idural "teroid In0ection

    Cer!ical rans#oramenal E)idural In0ection

  • 8/17/2019 Evidence for Spinal Interventions 2012

    93/100

    %ight nterior +liKue

  • 8/17/2019 Evidence for Spinal Interventions 2012

    94/100

    B

    Le#t CA ./.E.

  • 8/17/2019 Evidence for Spinal Interventions 2012

    95/100

    nterior ")inal rtery

    • I# )articulate material li,e

    de)ot steroid )re)aration is

    in0ected into the radicular

    !essels it could reach the "

    and s)inal cord and act as an

    em+olus

    • eedle trauma or air em+olus

     8untoon 7A" Pain ,**+2 )).: )*-3))

    9heshire P' et al" Neurolo# )1142 -.:5,)35*

    P !ie* o# an angiogram

  • 8/17/2019 Evidence for Spinal Interventions 2012

    96/100

    g g

    o+tained a#ter in0ection

    o# contrast medium

    Digital "u+traction 6ie*

    Con!entional #luorosco)ic

    ex)osure

    "ummary - Cer!ical E"I

  • 8/17/2019 Evidence for Spinal Interventions 2012

    97/100

    y• Cer!ical E"I

     –  Pros)ecti!e study *ith good results• Pain 18849 5&2: 23843.

    • Cer!ical /E"I –  3 Pros)ecti!e "tudy

    • Eur ")ine $ 188;9 5:318325

    • %adiology 2''19 21&:&&;&82• $% 2''49 253: 44145

     –  1 %C• P Drey#uss. Pain edicine 2'';9 A: 23A42 

     –  3'( o+tain com)lete relie# 

     –  3'( o+tain )artial7 lasting relie# 

     –  o +e tried +e#ore surgery

     –  In the a+sence o# controlled studies7 it cannot +e ,no*n *hetherthese outcomes are due to natural history7 /E"I or nons)eci#ictreatment e##ects

    Pulsed %adio#reKuency reatment

  • 8/17/2019 Evidence for Spinal Interventions 2012

    98/100

    Pulsed %adio#reKuency reatment

    #or %adicular euro)athic Pain

    • Dou+le +lind sham %C

    • P%/ ad0acent to the cer!ical D% com)ared to "ham

    • P%/ grou) com)ared to sham at 3 months sho*ed a signi#icantly

    +etter outcome *ith regards to the glo+al )ercei!ed e##ect 5'(im)ro!ement and 6" 2')oint )ain reduction

    • his translated to a o# 1.1 in the P%/ grou) com)ared *ith

    o# 3 in the sham grou)

    • "ix months a#ter the )rocedures7 the o# P%/ *as 1.; and ;

    #or the sham inter!ention. –  Van Zundert J, Patijn J, Kessels A, Lamé I, van Suijlekom H, van Kleef ! Pulsed radiofre"uen#$

    adja#ent to t%e #ervi#al dorsal root &an&lion in #%roni# #ervi#al radi#ular 'ain( a dou)le )lind s%am

    #ontrolled randomi*ed #lini#al trial! Pain +-./+-0/1+2(/-314+!

  • 8/17/2019 Evidence for Spinal Interventions 2012

    99/100

    "ummary

    • ost )atients *ith LBP7 nec, )ain and u))er and lo*er

    lim+ radicular )ain *ill reco!er *ith conser!ati!e

    management

    • Precision diagnostic techniKues allo*s us to identi#y the

    source o# )ersistent )ain guides #urther management

    • +taining a diagnosis sto)s #urther #utile in!estigations

    and )re!ent surgery

  • 8/17/2019 Evidence for Spinal Interventions 2012

    100/100

    han,