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8/17/2019 Evidence for Spinal Interventions 2012
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Evidence for Precision Diagnosis
and Management of Spinal Painand Radicular Pain
Dr Sanjeeva GuptaMD; DNB; FRC; F!PP; FFPMRC
Consultant in Pain Management and naest"esia
Bradford #eac"ing $ospitals N$S #rust
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%utline of t"e #al&
• '"at is Precision Diagnosis ( Management)
• *um+ar Facet ,oint Pain
• Sacroiliac ,oint Pain• *o-er *im+ Radicular Pain
• Failed Bac& Surger. S.ndrome
• Cervical /ial Pain• Cervicogenic $eadac"e
• 0pper *im+ Radicular Pain
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Location Location Location
Diagnosis
Diagnosis
Diagnosis
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Current diagnostic methods
1. History
2. Physical examination
3. Imaging
4. Blood tests
5. er!e conduction studies
"lide #rom Dr $ %ichardson
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&'( o# )atients *ith )ersistent lo*
+ac, )ain cannot +e diagnosed
using the con!entional model
"lide #rom Dr $ %ichardson
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Precision diagnostic methods
Principle:
1. Inner!ated
2. Bloc,ade - %elie#
3. "timulation Pain
"lide #rom Dr $ %ichardson
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euroanatomy o# the ")ine
• /acet 0oints su))lied +y edian Branches o# Dorsal %ami
• uter third o# nnulus /i+rosis richly inner!ated – Branches o# the "inu!erte+ral er!es
– he rey %ami Communicantes
– Lum+ar 6entral %ami
Bogdu, 7 et al. $ nat 18&19 132: 385;
Bogdu, 7 ")ine 18&39 &:2&;283.
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svn
ST
direct
branches
**1 disc1
verte+ra
ALL nerve plexus
svn
r. comm.
ST
PLL nerve plexus
P**1 dura1
disc1 verte+ra
#ter roen $ et al. m , nat 2334; 2556 757839
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?here does +ac, )ain come #rom@
1. /acet $oints
2. Discs
3. "acroiliac 0oint
4. er!e root > dura
5. 6erte+ral Body
;. Ligaments
A. uscles
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?here does +ac, )ain come #rom@
/acet $oint Pain
21( 4'( in general
)o)ulation
1;( in )ost lum+ar
surgery )atients /B""
"ch*ar=er et al. Spine 1884 Ann
Rheum Dis 1885
Datta "7 et al. Pain Physician 2''89
12: 43A4;'
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/acet $oint Pain E!aluation
• /acet $oint In0ections
• edial Branch Bloc,
• /alse )ositi!e rate 3'( – Datta "7 et al. Pain Physician 2''89 12: 43A4;'
High on the FeyeG o# the F"cotty dogG
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edian Branch Bloc, Diagnostic
• Lum+ar medial +ranch +loc,s ha!e +een
sho*n to ha!e +oth diagnostic and thera)eutic
utility – Datta "7 et al. Pain Physician 2''89 12:43A4;'.A4;'. – "ehgal 7 et al. Pain Physician 2''A9 1':21322&.
– Hancoc, $7 et al. Eur ")ine $. 2''A ct91;1':15385'.
– %u+instein "7et al. Best Pract %es Clin %heumatol 2''&9 22:4A14&2.
– I"I". Lum+ar BB. In: Bogdu, 7 ed. Practice uidelines #or ")inal Diagnostic and reatment
Procedures. "an/rancisco7 C: I"I"9 2''4:4A-;5.
– Cohen "P7et al. nesthesiology. 2'1' ug91132:3854'5. – Cohen "P7 et al. ")ine $. 2''& ay$un9&3:48&5'4
– Bogdu, : he inner!ation o# the lum+ar s)ine. ")ine 18&39 &:2&;283
– "ch*ar=er C7 et al. ")ine 18849 18:1132113A
– "ch*ar=er C7 et al. nn %heum Dis 18859 54:1''1';
– Drey#uss P7 et al. ")ine 188A9 22:&858'2
– a)lan 7 et al. ")ine 188&9 23:1&4A1&52
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hera)eutic E##ecti!eness o# Lum+ar7 horacic
and Cer!ical edian Branch Bloc,s
L": L 2''1 1 - 3 in0 - LJ"ara)in> LJ sara)in J steroid: L 2''& 3 - 4 in0
C": L 2''& L> LJ "teroid
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/acet $oint - %adio#reKuency Dener!ation
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"ummary o# In!alid "tudies o# /acet $oint
Dener!ation due to echnical /la*s
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Laclaire et al "tudy
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"ummary and utcomes o# 6alid
"tudies o# /acet $oint Dener!ation
• omBerme0o /7 et al. $ ")inal Disord ech. 2'11 )r9242:;8A5.• Do+rogo*s,i $7 et al. Pharmacol %e). 2''595A4:4A5&'.• "cho##erman $7 et al. E##ecti!eness o# re)eated %/D #or lum+ar #acet )ain.
2''4 o! 192821:24A13.
• ornic, C7 et al. Com)lications o# lum+ar #acet %/D. ")ine Phila Pa 18A;.
2''4 $un 1592812:13524.
LEE% HE EDI% P i Ph i i
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LEE% HE EDI% Pain Physician
itle: I %E"P"E
CritiKuing the critiKues: the merican Pain "ociety guideline and
the merican "ociety o#
Inter!entional Pain Physicians res)onse to it
• "hort itle: CritiKuing the critiKue
• Corres)onding uthor: "herdil ath
• "ir7
In the a+o!e letter to the editor7 %oger Chou im)lies that the results could +e +iased and concludes that7 I Kuote7
“It is difficult to see how the Nath et al trial could be taken as reliable evidence that radiofrequenc denervation iseffective!"
he reason #or this7 as Kuoted in the letter *as“because the sham control #roup $which had hi#her baseline scores% had #reater potential to e&perienceimprovement from baseline! here is a mista,e here as it *as the acti!e treatment grou) that had higher+aseline scores o# )ain7 ot the sham grou) as stated
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eneralised Pain
LEE% HE EDI% Pain Physician
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lo+al Im)ro!ement
LEE% HE EDI% Pain Physician
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here are se!en systematic re!ie*s o#
radio#reKuency dener!ation #or chronic LBP
uthor conclusions:
• Bos*ell 2''A: Me!idence #or )ain relie# *ith radio#reKuency neurotomy o# medial
+ranch ner!es *as moderate to strong in cer!ical and lum+ar s)ine.N
•Datta 2''8: Mle!el II2 e!idence #or radio#reKuency neurotomyN
•uerts 2''1 Mmoderate e!idence that radio#reKuency lum+ar #acet dener!ation *as more
e##ecti!e #or chronic lo* +ac, )ain than )lace+oN
•anchi,anti 2''2 Mmoderate to strong e!idence #or radio#reKuency neurotomyN
•iemisto 2''3 Mcon#licting shortterm e##ect on chronic lo* +ac, )ainN
•Bos*ell 2''5 Mmoderate to strong e!idence #or radio#reKuency neurotomyN
•"li)man 2''3 M the e!idence #or radio#reKuency dener!ation is Le!el III or moderate.N
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International Lo* Bac, Pain uidelines
• ICE C&&: htt):>>***.nice.org.u,>C&&
Do not re#er #or radio#reKuency dener!ation
• merican Pain "ociety Lo* +ac, )ain guideline
• htt):>>***.am)ainsoc.org>li+rary>)d#>LBPE!id%e!.)d#
E!idence on e##icacy o# %/ dener!ation o# the B o# the
)rimary dorsal ramus is di##icult to inter)ret
•Euro)ean Lo* Bac, Pain uideline
htt):>>***.+ac,)aineuro)e.org>*e+>#iles>?2Ouidelines.)d#
?e cannot recommend %/ #acet dener!ation #or )atients
*ith nons)eci#ic chronic lo* +ac, )ain
http://www.nice.org.uk/CG88http://www.ampainsoc.org/library/pdf/LBPEvidRev.pdfhttp://www.backpaineurope.org/web/files/WG2_Guidelines.pdfhttp://www.backpaineurope.org/web/files/WG2_Guidelines.pdfhttp://www.backpaineurope.org/web/files/WG2_Guidelines.pdfhttp://www.backpaineurope.org/web/files/WG2_Guidelines.pdfhttp://www.backpaineurope.org/web/files/WG2_Guidelines.pdfhttp://www.ampainsoc.org/library/pdf/LBPEvidRev.pdfhttp://www.ampainsoc.org/library/pdf/LBPEvidRev.pdfhttp://www.nice.org.uk/CG88http://www.nice.org.uk/CG88http://www.nice.org.uk/CG88
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International Lo* Bac, Pain uidelines• "IPP uideline Com)rehensi!e E!idenceBased uidelines #or
Inter!entional echniKues in the anagement o# Chronic
")inalPain:
htt):>>***.)ain)hysician0ournal.com>2''8>0uly>2''89129;88&'2.)d#
%ecommendation: Based on uyatt et alNs criteria7 #or lum+ar
radio#reKuency neurotomy the recommendation is 1C>strong
• merican "ociety o# naesthesiologists Practice uidelines #or
Chronic Pain anagement
htt):>>0ournals.l**.com>anesthesiology>/ulltext>2'1'>'4'''>Pract
iceOuidelinesO#orOChronicOPainOanagementO.13.as)x• %/ o# the B ner!es to the /$ should +e )er#ormed #or LBP *hen
)re!ious diagnostic or thera)eutic in0ections o# the 0oint or B ner!e
ha!e )ro!ided tem)orary relie# Category 1 e!idence
http://www.painphysicianjournal.com/2009/july/2009;12;699-802.pdfhttp://journals.lww.com/anesthesiology/Fulltext/2010/04000/Practice_Guidelines_for_Chronic_Pain_Management_.13.aspxhttp://journals.lww.com/anesthesiology/Fulltext/2010/04000/Practice_Guidelines_for_Chronic_Pain_Management_.13.aspxhttp://journals.lww.com/anesthesiology/Fulltext/2010/04000/Practice_Guidelines_for_Chronic_Pain_Management_.13.aspxhttp://journals.lww.com/anesthesiology/Fulltext/2010/04000/Practice_Guidelines_for_Chronic_Pain_Management_.13.aspxhttp://www.painphysicianjournal.com/2009/july/2009;12;699-802.pdf
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Precision Diagnosis andanagement
o# "acroiliac $oint "I$ Pain
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?here does +ac, )ain come #rom@"I$ Pain Pre!alence
21A )atients *ith maximal
)ain +elo* L5 e!aluated
– natomic controlled neg =0t +loc,s and>ordual )ositi!e A5( relie# "I$ +loc,s)er#ormed
– Pre!alence o# "I$ )ain *as 1'2'(
• "ch*ar=er7 ")ine7 2':317 18857 aigne7 ")ine 2171&&87 188;
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"I$ )ain +elo* a L>" #usion
Pre!alence
• In A4 com+ined )atients *ith lo* +ac, )aina#ter lum+osacral #usion7 the "I$ *as the )ainsource in 32( as esta+lished +y single I "I$in0ections – at=. $ ")inal Disorders 1;98;887 2''37 aigne. Euro
")ine $ 149;54;5&7 2''5
• "I$ *as #ound to +e a source o# )ost#usion )ain in 32( o# )atients +y singleI +loc,
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"I$ %e#erral Qones
• aximal "I$ )ain is +elo* L5 +ut can re#er
into the entire lo*er extremity *ith 84(
ha!ing +uttoc,7 4&( *ith thigh )ain and 2&(
*ith lo*er leg )ain• "ch*ar=er. ")ine 18857 aigne. ")ine 188;7 Drey#uss. ")ine 188;7 "li)man. rch Phys
ed %eha+il 2'''9&1:33433&
• Based on dual +loc,s7 maximal )ain is +elo*
L5 and in the +uttoc,
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"I$ Inter!entions
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he medial 0oint lines are the margins o# the )osterior
"I 0oint line arro*
C t t di d
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Contrast medium s)read
along the "I 0oint line
Dou+le eedle echniKue: n lternati!e ethod #or Per#orming
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Dou+le eedle echniKue: n lternati!e ethod #or Per#orming
Di##icult "I$ In0ections." u)ta. Pain Physician 2'119 14: 2&12&4
Dou+le eedle echniKue: n lternati!e ethod #or Per#orming
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Dou+le eedle echniKue: n lternati!e ethod #or Per#orming
Di##icult "I$ In0ections.
" u)ta. Pain Physician 2'119 14: 2&12&4n Dynamic /luorosco)y the needle is not in the "I$ line
Dou+le eedle echniKue #or "acroiliac $oint In0ection
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Dou+le eedle echniKue #or "acroiliac $oint In0ection" u)ta. Pain Physician 2'119 14: 2&12&4
"econd eedle in Inserted into the e*ly Identi#ied $oint Line on
Dynamic /luorosco)y
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Dou+le eedle echniKue #or "acroiliac $oint In0ection" u)ta. Pain Physician 2'119 14: 2&12&4
Contrast In0ected hrough the "econd eedle Identi#ies the "I$
Dou+le eedle echniKue #or "acroiliac $oint In0ection
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Dou+le eedle echniKue #or "acroiliac $oint In0ection" u)ta. Pain Physician 2'119 14: 2&12&4
Contrast In0ected rough the /irst eedle @ 6ascular ")read
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"I$ Inter!entions E!idence
• ost ex)erts maintain lo*!olume intraarticular local anaesthetic in0ections to +e the
only relia+le diagnostic modality to diagnose "I$
)ain – Cohen "P. "acroiliac 0oint )ain: a com)rehensi!e re!ie* o# anatomy7
diagnosis7 and treatment. nesth nalg. 2''591'1:144' - 1453
– Drey#uss P7 Dreyer "$7 Cole 7 et al. "acroiliac 0oint )ain. $ m cad
rtho) "urg. 2''4912:255 2;5
– Hansen HC7 cen=ieBro*n 7 Cohen "P7 et al. "acroiliac 0ointinter!entions: a systematic re!ie*. Pain Physician. 2''A91':1;5< &4.
"I$ I t ti E id
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"I$ Inter!entions E!idence
• here is one dou+le +lind and & )ros)ecti!e o+ser!ational studies
*hich conclude that /luorosco)y > C > %I guided "I$ in0ectiono# steroid )ro!ides good short to intermediate term )ain relie# 3
to ; months – augars
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"I$ %adio#reKuency E!idence
• 2 %C and 3 Pros)ecti!e o+ser!ational studies in#orm
that 5'( )atients o+tain 5'( )ain relie# *ith
im)ro!ed #unction #or ; months #ollo*ing "I$ %/D in
care#ully selected )atients #ollo*ing diagnostic in0ection
o# local anaesthetic into the "I$
– " P. Cohen7 et .al. %andomi=ed Place+ocontrolled "tudy E!aluating Lateral Branch %/D #or
"I$ Pain. nesthesiology 2''&9 1'8:2A8-&&
– Patel7 et al. %andomi=ed7 Place+o Controlled "tudy to ssess the E##icacy o# Lateral
Branch Dener!ation #or Chronic "I$ Pain. Presented at the "IPP nnual eeting $une 2'11 – " P. Cohen7 et al. utcome Predictors #or "acroiliac $oint Lateral Branch%adio#reKuency
Dener!ation. %eg nesth Pain ed 2''89 34: 2'; - 214
– H araman7 et al. cta eurochir 2'11. Pu+lished online )ril 2'113
– Bui0s E$7 et al. Pain Clinic 2''49 1;: 13814;.
– e!arge= 7 et al. Eur %adiol 2''29 12: 13;'13;5
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lancinating1 s"ooting1 or
:electric pain; traveling
do-n t"e lim+ in a
narro- +and<
RD!C0*R P!N
Presentation can
alter if treated
Bogdu& N1 Govind ,< Medical Management of cute *um+ar Radicular Pain< n Evidence8Basedpproac"< Ne-castle6 Ne-castle Bone and ,oint !nstitute1 2333
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echanism - I/LI
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spinal nerve
dorsal root
ganglion
RD!C0*R P!N
N%
P*7 P*E7
#NF
interleu&ins 51 27
metalloproteinases
!g M1 !g G
!NF*MM#!%N
leu&otriene B=
t"rom+a/ane
interferon
macrop"ages
l.mp"oc.tes
fi+ro+lasts
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spinal nerve
dorsal root
ganglion
RD!C0*R P!N
N%
P*7 P*E7
#NF
interleu&ins 51 27
metalloproteinases
!g M1 !g G
!NF*MM#!%N
leu&otriene B=
t"rom+a/ane
interferon
macrop"ages
l.mp"oc.tes
fi+ro+lasts
S#ER%!DS
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%adicular Pain
• E)idurals - Caudal7 Interlaminar7
rans#oramenal
• Catheter euro)lasty
• ")inal endosco)y
• ")inal cord stimulator
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Caudal E)idural "teroid In0ection #or
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Caudal E)idural "teroid In0ection #or
Lum+ar disc herniation>radiculitis
Dash#ield - "ingle )rocedure
L - L>LJ"teroid9 !erage )rocedure 3 to 4>year *ith 5'( )ain relie# and 4'( im)ro!ement o# DI o# 3;>5"igni#icant decrease in o)ioid inta,e and em)loyment status 12>52 )er )rocedure
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Caudal E)idural "teroid In0ection
LBP o# Post "urgery "yndrome
L and %e!el - Post lum+ar laminectomy syndrome9 L DB eKui!alence trial9 L or L J Betamethasone9
!erage )rocedure 3 to 4>year9 5'( )ain relie# and 4'( im)ro!ement o# DI o# 3544>52
"igni#icant decrease in o)ioid inta,e 1'14>52 )er )rocedure
Hesla - herniated disc o)erated
L + I t l i E id l "t id I 0 ti
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Lum+ar Interlaminar E)idural "teroid In0ection
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"ummary - Lum+ar E"I
•15 %CNs: & )ositi!e and A negati!e
– %adicular )ain relie# +et*een ; *,s 3 mths• o #luorosco)y• In the )osterior e)idural s)ace
• @dhesions
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rans#oraminal E)idural
%andomised rials o# E##ecti!eness o#
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%andomised rials o# E##ecti!eness o#
rans#oramenal E)idural In0ection
hahreman 7 /erch %7 Bogdu, . Pain edicne 2'1'9 11: 114811;&
hahreman 7 Bogdu, . Pain ed. 2'11 $un912;:&A18.
Le#t L4>5 rans#oraminal In0ection
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Le#t L4>5 rans#oraminal In0ection
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i $ t l " i 2''1 23 25&A
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ar))inen $7 et al. ")ine 2''19 23: 25&A
85
• Cost e##ecti!eness o# /E"I #or sciatica
• /or contained herniations
– "teroid +etter #or leg )ain7 disa+ility7 "L% in the short
term
– By 1 year steroid )re!ented o)erations costing
R127;;; less )er res)onder
• /or extrusions – "teroid seemed to increase the o). rate and *as more
ex)ensi!e
%ie* D7 et al: Pros)ecti!e %C Dou+le Blind rial
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7 )he main outcome measure *as a!oidance o# surgery
Bu)i!acaine and
Betamethasone
Bu)a!acaine only
otal Patients 2& 2A
Patients notha!ing surgery 2' A1(
P S '.'''4
8 33(
Normall. all -ould "ave +een treated operativel.
#reatment algorit"m no- includes > to = #FES! +efore considering surger.
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# i l L l th ti I 0 ti
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rans#oraminal Local naesthetic In0ection
# i l "t id I 0 ti
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rans#oraminal "teroid In0ection
Change in Tse o# Health Care #rom +e#ore to a#ter treatment
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Change in Tse o# Health Care #rom +e#ore to a#ter treatment
Degree o# Pain %elie# in the 5 di##erent rou)s
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Degree o# Pain %elie# in the 5 di##erent rou)s
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/E"I "ystematic %e!ie*s
• DePalma $7 et al. rch Phys ed %eha+il. 2''59&;A:14AA&3 – he e!idence #or /E"Is re!eals le!el III moderate e!idence in su))ort o#
these minimally in!asi!e and sa#e )rocedures in treating )ain#ul lum+ar
radicular sym)toms. Current studies su))ort use o# /E"Is as a sa#e and
minimally in!asi!e ad0unct treatment #or lum+ar radicular sym)toms.
• +di "7 et al. Pain Physician. 2''A $an91'1:1&5212.
– he e!idence #or cer!ical and lum+ar /E"I is moderate #or longterm
im)ro!ement in managing ner!e root )ain.
• %o+erts "7 et al. P %. 2''8 $ul91A:;5A;&.
– here is #air e!idence su))orting /E"Is as su)erior to )lace+o #or treatingradicular sym)toms.
– here is good e!idence that /E"Is should +e used as a surgerys)aring
inter!ention
– /E"Is are su)erior to interlaminar E"Is ILE"Is and caudal E"Is #or
radicular )ain in )atients *ith su+acute or chronic radicular sym)toms.
/E"I "ystematic %e!ie*s
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/E"I "ystematic %e!ie*s
• Buena!entura %7 et al. Pain Physician. 2''8 $an/e+9121:23351
– he indicated e!idence #or /E"I is Le!el II1 #or shortterm relie# and
Le!el II2 #or longterm im)ro!ement in the management o# lum+ar ner!e
root and lo* +ac, )ain
• anchi,anti L7 et al. Pain Physician. 2''89124:E1238&. – Based on uyatt et alNs criteria7 the recommendation #or lum+ar /E"I is
1C>strong in managing chronic lo* +ac, and lo*er extremity )ain
• Benny B7 et al. $ Bac, usculos,elet %eha+il. 2'11 $an
19242:;AA; – here *as strong e!idence #or /E"I in the treatment o# lum+osacral
radicular )ain #or +oth short term and long term relie#
8/17/2019 Evidence for Spinal Interventions 2012
68/100
8/17/2019 Evidence for Spinal Interventions 2012
69/100
8/17/2019 Evidence for Spinal Interventions 2012
70/100
8/17/2019 Evidence for Spinal Interventions 2012
71/100
ur %es)onse
Care#ul )atient selection7 #luorosco)y and contrast
in0ection are needed #or e##ecti!e s)inal in0ections.
on7 2'11'82; 11:58
htt):>>***.+m0.com>content>343>+m0.d52A&@ta+res)onses
http://www.bmj.com/content/343/bmj.d5278?tab=responseshttp://www.bmj.com/content/343/bmj.d5278?tab=responseshttp://www.bmj.com/content/343/bmj.d5278?tab=responses
8/17/2019 Evidence for Spinal Interventions 2012
72/100
euromodulation
– ICE echnology a))raisal guidance 158
• %ecommended #or chronic )ain o# neuro)athic
origin
• /ailed Bac, "urgery "yndrome
• Com)lex %egional Pain "yndrome
8/17/2019 Evidence for Spinal Interventions 2012
73/100
Cervical Spinal Pain and 0pper
*im+ Radicular Pain Spinal
• Diagnosis anagement o# ec, Pain
• Diagnosis and anagement o# %adicular Pain
?here does the Pain Come /rom@
8/17/2019 Evidence for Spinal Interventions 2012
74/100
?here does the Pain Come /rom@
• /acet $oints
• Inter!erte+ral Discs
•Ligaments
• Dura mater
• er!e %oot7 D%
• Bone – In#ection7 rauma7 umour
• uscles
Discs: roen. m $ nat 188'9 &&:2&28;
Bogdu,. ")ine 18&&913:2&
endal. ")ine 18829 1A:13235
/acet $oints: Bogdu,. ")ine 18&29 A:3183'
C i > i i
8/17/2019 Evidence for Spinal Interventions 2012
75/100
Cer!ical > ec, Pain Incidence
• Lo*er Cer!ical /acet $oint PainC4>5 to C;>A
– +out 5'( *ith nec, )ain• Spine )11,2 ).:.--3-.2 Spine )1142 ,):).5.3-+2 Spine )11+2 ,*: ,*3,4
– High s)eed 6 - &&( 6 of 7usculoskeletal Pain ,***2 0: 0.31+
• T))er Cer!ical /$ Pain Cer!icogenic Headache C'>1 to C3>4
– 53( #rom C23 0oint 6 Neurol Neurosur# Pschiatr )11-2 +.: ))0.31*
$istor. and Clinical E/amination6 Cervical Somatic Referred Pain
•Facet ,oint Pain
8/17/2019 Evidence for Spinal Interventions 2012
76/100
C?89
C>8=
C78>
C=8?
C98@
•Facet ,oint Pain
•Discogenic Pain
D-.er et al< Spine 2334; 2?6=?>8=?@ Gru++ and Aell.< Spine 7444; 7?62>5782>53
C5; #acet 0oint most commonly
in!ol!ed #ollo*ed +y C;A
ne can localise to *ithin
J> one 0oint on the +asis
o# re#erral ma)s
8/17/2019 Evidence for Spinal Interventions 2012
77/100
C>
C=
C?
C9
ap
/luorosco)ic natomy
Centroid o# the articular )illar
C2 C2
C4
C5
/alse Positi!e Bloc,s
8/17/2019 Evidence for Spinal Interventions 2012
78/100
/alse Positi!e Bloc,s
• !erage #alse )ositi!e rate o# single +loc,
*as 48( range 2A to ;3( – Barnsley et al. he Clinical $ournal o# Pain 18839 8:12413'
– anchi,anti et al. Pain Pract 2''&9 &:51'
– anchu,onda %7 et al. $ ")inal Disord ech 2''A9 2': 53845
edian Branch eurotomy E!idence
8/17/2019 Evidence for Spinal Interventions 2012
79/100
edian Branch eurotomy E!idence
Lord "7 Bogdu, 7 et al. %adio#reKuency eurotomy #or ChronicQyga)o)hyseal
$oint Pain. he e* England $ournal o# edicine 188;9 335:1A211A2;
• %andomised dou+le+lind trail
• 24 )atients #ollo*ing 6• "ource o# )ain identi#ied +y dou+le+lind )lace+o
controlled L +loc,s "aline7 lignocaine7 Bu)i!acaine
• 12 )atients recei!ed %/ neurotomy C3>4 to C;>A• edian time +e#ore )ain returned to 5'( o# the
)reo)erati!e le!el *as 2;3 days in the acti!e
treatment grou) and & days in the control grou)
edian Branch eurotomy E!idence
8/17/2019 Evidence for Spinal Interventions 2012
80/100
edian Branch eurotomy E!idence
cDonald $7 Lord "7 Bogdu, . Long term #ollo*u) o# )atients treated *ith
cer!ical radio#reKuency neurotomy #or chronic nec, )ain. eurosurgery 1888945: ;1;&
• 2& )atients treated - 1& ;4( had com)lete )ain
relie# #or a median )eriod o# 421 days
• I# )ain recurred com)lete )ain relie# reinstated
+y re)eat %/ neurotomy *ith some )atients
ha!ing 4 to ; success#ul re)etitions
"a)ir D et al. %/ B neurotomy in litigant and nonlitigant
)atients *ith cer!ical *hi)lash. ")ine 2''19 2;: E2;&E2A3
8/17/2019 Evidence for Spinal Interventions 2012
81/100
edian Branch eurotomy E!idence
Cer!icogenic Headache
8/17/2019 Evidence for Spinal Interventions 2012
82/100
hird cci)ital er!e
• C23 $oint is the source o# Cer!icogenic Headache in
54( o# )atients
• C3: three )oints reKuired7 to co!er !ariants in
location• longitudinal +isector C23 =yga)o)hysial 0oint
– High o))osite a)ex o# C3 "P
– Lo* o))osite +ase o# C23 #oramen – mid mid*ay +et*een
8/17/2019 Evidence for Spinal Interventions 2012
83/100
B
longitudinal bisector longitudinal bisector high, mid, and low pointshigh, mid, and low points
TARGT P!"#TS $!R T%"R& !''"P"TAL #R(TARGT P!"#TS $!R T%"R& !''"P"TAL #R(
- E!idence
8/17/2019 Evidence for Spinal Interventions 2012
84/100
o!ind $7 Bogdu, 7 et al. %adio#reKuency neurotomy #or the
treatment o# third occi)ital headache. $ eurol eurosurg Psychiat
2''39 A4: &&83
• &;( o# 48 )atients o+tained com)lete )ain
relie#7 the median duration o# )ain relie# *as28A days
• 14 )atients had re)eat %/ neurotomy *hen
their )ain recurred and 12 &;( regained
com)lete )ain relie#
8/17/2019 Evidence for Spinal Interventions 2012
85/100
Cer!ical Pain lgorithm
Cer!ical > ec, Pain
8/17/2019 Evidence for Spinal Interventions 2012
86/100
Cer!ical > ec, Pain/acet 0oints
• Headache Dominant "ym)tom- T))er cer!ical #acets
• Headache ot Dominant - iddle and Lo*er Cer!ical
/acets
D-.er et al< Spine 2334; 2?6=?>8=?@
C78>
C=8?
C98@
C>8=
C?89
Cer!ical > ec, Pain lgorithm
8/17/2019 Evidence for Spinal Interventions 2012
87/100
Cer!ical > ec, Pain lgorithm
Cer!ical Pain
@T))er Lim+ Pain Cer!ical xial Pain
o T))er Lim+ %adicular Pain
@Cer!ical %adicular Pain
5'&'( ha!e nec, )ain
8/17/2019 Evidence for Spinal Interventions 2012
88/100
Cer!ical /acet $oint Pain lgorithm
"elect ost Li,ely $oint /rom Pain a)s Per#orm /irst Bloc, C5; common
8'( Pain %elie# C;A7 C457 CA1
8/17/2019 Evidence for Spinal Interventions 2012
89/100
Cer!icogenic Headache lgorithm
Per#orm C23 $oint Bloc, 54(
ood Pain %elie# o Pain %elie#-C34 +loc,
echnically deKuate@
Can C12 +loc, +e done sa#ely
Per#orm Con#irmatory Bloc, echnically deKuate@
8/17/2019 Evidence for Spinal Interventions 2012
90/100
Does the )ain satis#y the de#inition o# Cer!ical %adicular Pain
o
8/17/2019 Evidence for Spinal Interventions 2012
91/100
Cer!ical Interlaminar E)idural "teroid In0ections
l*ays +elo* C; le!el
Ideally CA1 le!el or +elo*
T))er Lim+ %adicular Pain
C i l E id l "t id I 0 ti
8/17/2019 Evidence for Spinal Interventions 2012
92/100
Cer!ical E)idural "teroid In0ection
Cer!ical rans#oramenal E)idural In0ection
8/17/2019 Evidence for Spinal Interventions 2012
93/100
%ight nterior +liKue
8/17/2019 Evidence for Spinal Interventions 2012
94/100
B
Le#t CA ./.E.
8/17/2019 Evidence for Spinal Interventions 2012
95/100
nterior ")inal rtery
• I# )articulate material li,e
de)ot steroid )re)aration is
in0ected into the radicular
!essels it could reach the "
and s)inal cord and act as an
em+olus
• eedle trauma or air em+olus
8untoon 7A" Pain ,**+2 )).: )*-3))
9heshire P' et al" Neurolo# )1142 -.:5,)35*
P !ie* o# an angiogram
8/17/2019 Evidence for Spinal Interventions 2012
96/100
g g
o+tained a#ter in0ection
o# contrast medium
Digital "u+traction 6ie*
Con!entional #luorosco)ic
ex)osure
"ummary - Cer!ical E"I
8/17/2019 Evidence for Spinal Interventions 2012
97/100
y• Cer!ical E"I
– Pros)ecti!e study *ith good results• Pain 18849 5&2: 23843.
• Cer!ical /E"I – 3 Pros)ecti!e "tudy
• Eur ")ine $ 188;9 5:318325
• %adiology 2''19 21&:&&;&82• $% 2''49 253: 44145
– 1 %C• P Drey#uss. Pain edicine 2'';9 A: 23A42
– 3'( o+tain com)lete relie#
– 3'( o+tain )artial7 lasting relie#
– o +e tried +e#ore surgery
– In the a+sence o# controlled studies7 it cannot +e ,no*n *hetherthese outcomes are due to natural history7 /E"I or nons)eci#ictreatment e##ects
Pulsed %adio#reKuency reatment
8/17/2019 Evidence for Spinal Interventions 2012
98/100
Pulsed %adio#reKuency reatment
#or %adicular euro)athic Pain
• Dou+le +lind sham %C
• P%/ ad0acent to the cer!ical D% com)ared to "ham
• P%/ grou) com)ared to sham at 3 months sho*ed a signi#icantly
+etter outcome *ith regards to the glo+al )ercei!ed e##ect 5'(im)ro!ement and 6" 2')oint )ain reduction
• his translated to a o# 1.1 in the P%/ grou) com)ared *ith
o# 3 in the sham grou)
• "ix months a#ter the )rocedures7 the o# P%/ *as 1.; and ;
#or the sham inter!ention. – Van Zundert J, Patijn J, Kessels A, Lamé I, van Suijlekom H, van Kleef ! Pulsed radiofre"uen#$
adja#ent to t%e #ervi#al dorsal root &an&lion in #%roni# #ervi#al radi#ular 'ain( a dou)le )lind s%am
#ontrolled randomi*ed #lini#al trial! Pain +-./+-0/1+2(/-314+!
8/17/2019 Evidence for Spinal Interventions 2012
99/100
"ummary
• ost )atients *ith LBP7 nec, )ain and u))er and lo*er
lim+ radicular )ain *ill reco!er *ith conser!ati!e
management
• Precision diagnostic techniKues allo*s us to identi#y the
source o# )ersistent )ain guides #urther management
• +taining a diagnosis sto)s #urther #utile in!estigations
and )re!ent surgery
8/17/2019 Evidence for Spinal Interventions 2012
100/100
han,