Epiblast Stem Cells Fusarium Head Blight in Latin Biotechnology … · 2013-07-04 · Fusarium spp. Enzymes Associated with Pathogenesis and Loss of Commercial Value of ... Cell-surface

Life Sciences springer.com/NEWSonline

118

R. Alberio, University of Nottingham, Loughborough, UK (Ed)

Epiblast Stem CellsMethods and Protocols

Features 7 Serves as a resource to individuals interested in studying the biology of pluripotent cells 7 Pro-vides step-by-step detail essential for reproducible results 7 Contains key notes and implementa-tion advice from the experts

Contents Generation and Characterization of Epiblast Stem Cells from Blastocyst-stage Mouse Embryos.- Re-version of Mouse Post-Implantation Epiblast Stem Cells to a Naïve Pluripotent State by Modulation of Signalling Pathways.- Converting Mouse Epi-blast Stem Cells into Mouse Embryonic Stem Cells by using Small Molecules.- Isolation and Culture of Rabbit Embryonic Stem Cells.- Goat Embryonic Stem-like Cell Derivation and Characterization.- Derivation and Culture of Canine Embryonic Stem Cells.- Isolation and Culture of Porcine Embryonic Stem Cells.- Isolation and Culture of Pig Epiblast Stem Cells.- Isolation and Culture of Bovine Embryonic Stem Cells.- Analysis of Molecular Markers for Staging Peri-gastrulating Bovine Embryos.- Chicken Embryonic Stem Cells: Establishment and Characterization.- Manipulat-ing the Avian Epiblast and Epiblast-derived Stem Cells.- Stepwise Differentiation from Naïve State Pluripotent Stem Cells to Functional Primordial Germ Cells through an Epiblast-like State.- Isola-tion and Culture of Porcine Neural Progenitor Cells from Embryos and Pluripotent Stem Cells.- Derivation of Neural Precursors from Bovine Pre-implantation Embryos.

Fields of interestCell Biology; Stem Cells

Target groupsProfessional/practitioner

Product categoryContributed volume

Due August 2013

2013. X, 220 p. 49 illus., 34 in color. (Methods in Molecular Biology, Volume 1074) Hardcover7 * € (D) 101,64 | € (A) 104,49 | sFr 126,507 € 94,99 | £85.50ISBN 978-1-62703-627-6

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T. M. Alconada Magliano, La Plata National University, Argentina; S. N. Chulze, Rio Cuarto National University, Argentina (Eds)

Fusarium Head Blight in Latin AmericaContents List of Contributors.- Preface.- Part I: Fusarium Populations Associated with Fusarium Head Blight in Latin America.- 1. Population Struc-ture of Fusarium graminearum Species Com-plex Genotypes and Chemotypes in Relation to Trichothecene Production.- 2. Species Identifica-tion, Genetic Diversity and Phenotypic Variation Studies on the Fusarium graminearum Complex Populations from Brazil.- 3. Diversity of Pathogen Populations Causing Fusarium Head Blight of Wheat in Uruguay.- 4. Ecophysiology of Fu-sarium graminearum Main Pathogen Associated to Fusarium Head Blight in Latin America.- Part II: Mycotoxins.- 5. Mycotoxins Associated to Fusarium Species that Caused Fusarium Head Blight in Wheat in Latin-America.- 6. Fusarium Mycotoxins. An Overview of Chemical Character-ization and Techniques for its Determination from Agricultural Products.- Part III: Interaction Plant Pathogen.- 7. Fungal Infection and Disease Pro-gression. Fusarium spp. Enzymes Associated with Pathogenesis and Loss of Commercial Value of Wheat Grains.- 8. Proteomic Approaches to Ana-lyze Wheat-Fusarium graminearum Interaction.- Part IV: Epidemiology.- 9. Crop Residues and their Management in the Epidemiology of Fusarium Head Blight.- Part V: Management of Fusarium Head Blight.- 10. Integrated Disease Management of Fusarium Head Blight.- 11. Chemical Control of Fusarium Head Blight of Wheat.- 12. Biological Control of Fusarium Head Blight of Wheat: From Selection to Formulation. [...]

Fields of interestPlant Pathology; Fungus Genetics

Target groupsResearch


Due August 2013

2014. X, 329 p. 50 illus., 4 in color. Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-94-007-7090-4

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T. Asakura, Tokyo University of Agriculture and Technology, Koganei, Japan; T. Miller, University California - Riverside, Riverside, CA, USA (Eds)

Biotechnology of SilkThis book is a snapshot of the current state of the art of research and development on the properties and characteristics of silk and their use in medi-cine and industry.

Features 7 Latest in molecular biology description of silk protein and nucleotide basis 7 Advances in research on both spider and insect silks are included 7 New applications of silk products, especially to Biomaterials

Contents 1. Wild silk production to support farmers excluded from protected areas of Madagascar.- 2. Evolutionary divergence of Lepidopteran and trichopteran fibroins.- 3. The Structure, Silk I and Lamella of (Ala-Gly)15 as the model of Bombyx mori silk fibroin studied with solid state NMR.- 4. Silk fibroin biomaterials for vascular regeneration.- 5. Evolution and application of coiled coil silks from insects. - 6. Characteriza-tion of underwater silk proteins from caddisfly larva, Steophysche marmorata.- 7. Atomic force microscopy and spectroscopy of silk from spider draglines, capture-web spirals, and silkworms.- 8. Modular spider silk fibers: Defining new modules and optimizing fiber properties.- 9. How to pass the gap - Functional morphology and biomechan-ics of spider bridging threads.- 10. The power of recombinant spider silk proteins.- 11. Prey capture adhesives produced by orb-weaving spiders.- 12. Silk and web synergy: The merging of material and structural performance.

Fields of interestEntomology; Biotechnology; Structural Materials



Due November 2013

2014. X, 390 p. 77 illus., 49 in color. (Biologically-Inspired Systems, Volume 5) Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-94-007-7118-5

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www.springer.com/978-1-62703-627-6



News 7/2013 Life Sciences

119

L. W. Barrett, S. Fletcher, S. D. Wilton, The University of Western Australia, Crawley, WA, Australia

Untranslated Gene Regions and Other Non-coding ElementsRegulation of Eukaryotic Gene Expression

There is now compelling evidence that the com-plexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a par-ticular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.

Features 7 Revisits the idea of "junk" genetic materi-al 7 Easy to read, concise overview of a complex subject

Contents Introduction.- Promoter.- 5’ Untranslated Region.- Structure.- Intronic Regions.- 3’ Untranslated Region.- Non-coding RNAs.- Conclusion.

Fields of interestAnimal Genetics and Genomics; Plant Genetics & Genomics; Gene Function


Product categoryBrief

Due July 2013

2013. VIII, 55 p. 2 illus. in color. (SpringerBriefs in Biochemistry and Molecular Biology) Softcover7 * € (D) 53,49 | € (A) 54,99 | sFr 67,007 € 49,99 | £44.99ISBN 978-3-0348-0678-7

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G. Battail, Chabeuil, France

Information and LifeContents 1. Introduction.- 2. What is information? 2.1 Information in a usual meaning. 2.2 Features of information as a scientific entity. 2.3 Comments on the definitions of information. 2.4 An informa-tion as a nominable entity. 2.5 Short history of communication engineering. 2.6 Communication over space or over time.- 3. Basic principles of communication engineering. 3.1 Physical inscrip-tion of a single symbol. 3.2 Physical inscription of a sequence. 3.3 Receiving a binary symbol in the presence of noise. 3.4 Communicating sequences in the presence of noise.- 4. Information theory for literal communication. 4.1 Shannon’s paradigm and its variants. 4.2 Quantitative measures of information. 4.3 Source coding.- 5. Channel capacity and channel coding. 5.1 Channel models. 5.2 Capacity of a channel. 5.3 Channel cod-ing needs redundancy. 5.4 On the fundamental theorem of channel coding. 5.5 Error-correcting codes.- 6. Information as a fundamental entity. 6.1 Algorithmic information theory. 6.2 Emergent information in populations. 6.3 Physical entropy and information. 6.4 Information bridges the abstract and the concrete.- 7. An introduction to the second part. 7.1 Relationship with biosemiot-ics. 7.2 Content and spirit of the second part.- 8. Heredity as a communication problem. 8.1 The enduring genome. 8.2 Consequences meet biologi-cal reality. 8.3 A toy living world. 8.4 Identifying genomic error-correcting codes.- 9. Information is specific to life. 9.1 Information and life are indis-solubly linked. 9.2 Semantic feedback loops. 9.3 Information as a fundamental entity. 9.4 Nature as an engineer.- 10. Life within the physical world. 10.1 A poorly understood divide. 10.2 Maxwell’s demon in physics and in life. [...]

Fields of interestLife Sciences, general; Philosophy of Biology; Information and Communication, Circuits


Product categoryMonograph

Due August 2013

2014. XII, 262 p. Hardcover7 * € (D) 149,79 | € (A) 153,99 | sFr 186,507 € 139,99 | £126.00ISBN 978-94-007-7039-3

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T. A. Baudino, Texas A&M Health Science Center, Temple, TX, USA (Ed)

Cell-Cell InteractionsMethods and Protocols

Features 7 Present current up-to-date methodolo-gies 7 Provides step-by-step detail essential for reproducible results 7 Contains key notes and implementation advice from the experts

Contents Proteomics Analysis of Contact-initiated Eph Receptor-ephrin Signaling.- Control of Vascu-lar Tube Morphogenesis and Maturation in 3D Extracellular Matrices by Endothelial Cells and Pericytes.- Analyzing Cell-cell Interactions in 3-dimensional Adhesion Assays.- Production of Spontaneously Beating Neonatal Rat Heart Tissue for Calcium and Contractile Studies.- Paracrine Communication Between Mechanically Stretched Myocytes and Fibroblasts.- Assessing Blood Brain Barrier Function using in vitro Assays.- Methods to Assess Tissue Permeability.- In vivo Quantifica-tion of Metastatic Tumor Cell Adhesion in the Pulmonary Microvasculature.- Cell Membrane Vesicles as a Tool for the Study of Direct Epithe-lial-stromal Interaction: Lessons from CD147 .- Microencapsulation of Stem Cells to Study Cel-lular Interactions.- Cell-surface Protein-protein Interaction Analysis with Time-resolved FRET and Snap-tag Technologies.- Single Cell Analysis of Lipid Rafts.- Micropatterning Cell Adhesion on Polyacrylamide Hydrogels.- Measuring Cell-cell Tugging Forces using Bowtie-patterned mPADs (Microarray Post Detectors).- Generation and Analysis of Biosensors to Measure Mechanical Forces within Cells.- Proteomic Analysis of the Left ventricle Post-myocardial Infarction to Iden-tify in vivo Candidate Matrix Metalloproteinase Substrates.

Fields of interestCell Biology; Cell Physiology



Due August 2013

2nd ed. 2013. X, 220 p. 48 illus., 29 in color. (Methods in Molecular Biology, Volume 1066) Hardcover7 * € (D) 101,64 | € (A) 104,49 | sFr 126,507 € 94,99 | £85.50ISBN 978-1-62703-603-0

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120

B. Berg, University of Uppsala, Sweden; C. McClaugherty, Mount Union University, Alliance, OH, USA

Plant LitterDecomposition, Humus Formation, Carbon Sequestration

Since the publication of the 2nd edition, there have been substantial developments in the field of litter decomposition. This fully revised and updated 3rd edition of Plant Litter reflects and discusses new findings and re-evaluates earlier ones in light of recent research and with regard to current areas of investigation.

Features 7 Third edition, fully revised and updated with much new material 7 New information emphasizes on three fields: the effects of manga-nese on decomposition and possibly on carbon sequestration, new results on decomposition dynamics, and the new analytical technique using 13C-NMR 7 In-depth approach to the results of long-term studies

Contents Introduction.- Decomposition as a process – some main features.- Decomposer organisms.- Initial litter chemical composition.- Changes in substrate composition during decomposition.- Chemical constituents as rate regulating: initial variation and changes during decomposition. New and traditional analytical techniques.- Climatic envi-ronment.- Decomposition of fine root and woody litter.- Models that describe litter decomposi-tion.- Some possible influences on decomposition pattern, regression model, stable fraction and C sequestration.- Does humus accumulate and where? What factors may influence? Estimating carbon sequestration rates on a regional scale.

Fields of interestEcology; Geoecology/Natural Processes; Nature Conservation



Due August 2013

3rd ed. 2013. XVII, 317 p. 92 illus. Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-3-642-38820-0

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I. Castellano, Stazione Zoologica Anton Dohrn, Naples, Italy; A. Merlino, University of Naples, Italy

Gamma-Glutamyl TranspeptidasesStructure and Function

Gamma-Glutamyl Transpeptidases (γ-GTs) are members of the N-terminal nucleophile hydrolase superfamily, enzymes that cleave the γ-glutamyl amide bond of glutathione to liberate cysteinyl-glycine. The released γ-glutamyl group can be transferred to water (hydrolysis) or to amino acids or short peptides (transpeptidation). γ-GT plays a key role in the gamma glutamyl cycle by regulating the cellular levels of the antioxi-dant glutathione, hence it is a critical enzyme in maintaining cellular redox homeostasis.γ-GT is upregulated during inflammation and in several human tumors, and it is involved in many physi-ological disorders related to oxidative stress, such as Parkinson’s disease and diabetes. Furthermore, this enzyme is used as a marker of liver disease and cancer. This book covers current knowledge about the structure-function relationship of γ-GTs and gives information about applications of γ-GTs in different fields ranging from clinical biochemis-try to biotechnology and biomedicine.

Feature 7 Comprehensive, up-to-date overview

Contents 1 Introduction.- 2 Occurrence, genes and gene expression.- 3 Structure and function of γ-GTs.- 4 Autoprocessing and reaction mechanism of γ-GTs.- 5 γ-GT in bioclinical.- 6 γ-GTs: biotech-nological and biomedical applications.- 7 Conclu-sions.- References.

Fields of interestEnzymology; Human Physiology; Biochemical Engineering



Due July 2013

2013. VIII, 57 p. 28 illus., 18 in color. (SpringerBriefs in Biochemistry and Molecular Biology) Softcover7 * € (D) 53,49 | € (A) 54,99 | sFr 67,007 € 49,99 | £44.99ISBN 978-3-0348-0681-7

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T. Elmqvist, Stockholm University Stockholm Resilience Centre, Stockholm, Sweden; M. Fragkias, Boise State University College of Business and Economics, Boise, ID, USA; J. Goodness, Stockholm University, Stockholm, Sweden; B. Güneralp, Texas A&M University Hunter College, College Station, TX, USA; P. J. Marcotullio, City University of New York (CUNY) Hunter College, New York, NY, USA; R. I. McDonald, The Nature Conservancy, Arlington, VA, USA; S. Parnell, University of Cape Town, Rondebosch, South Africa; M. Sendstad, M. Schewenius, Stockholm University, Stockholm, Sweden; K. C. Seto, Yale University, New Haven, CT, USA; C. Wilkinson, Stockholm University, Stockholm, Sweden (Eds)

Urbanization, Biodiversity and Ecosystem Services: Challenges and OpportunitiesA Global Assessment

Contents 1. A global outlook on urbanization; Karen Seto et al.- 2. History of urbanization and the missing ecology; Thomas Elmqvist et al.- 3. Urbanization and global trends in biodiversity and ecosystem services; Robert McDonald et al. 4. Regional assessment of Asia with special focus on China, India, and Indonesia.- 5. Patterns and trends in ur-ban biodiversity and design; Norbert Müller et al. 6. Urban ecosystem services; Erik Gómez-Bagget-hun et al.- 7. Shrinking cities, biodiversity and ecosystem services; Dagmar Haase.- 8. Regional assessments of Europe, North America, and Ocea-nia.- 9. Projections of global urbanization; Michail Fragkias et al.- 10. Urbanization forecasts, effects on land use, biodiversity, and ecosystem services; Burak Güneralp et al.- 11. Regional assessment of Africa.- 12. Climate change and urban vulnerabil-ity; William Solecki and Peter Marcotullio. [...]

Fields of interestUrban Ecology; Urbanism; Sustainable Develop-ment



Due August 2013

2014. XIV, 386 p. Hardcover7 approx. * € (D) 53,45 | € (A) 54,95 | sFr 66,507 approx. € 49,95 | £44.99ISBN 978-94-007-7087-4

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121

T. Fenning, Forestry Commission, Edinburgh, UK (Ed)

Challenges and Opportunities for the World’s Forests in the 21st CenturyContents Foreword.- Introduction.- PART 1. Sustain-able Forestry & Conservation Objectives.- 1. A Burning Issue: Tropical Forests and the Health of Global Ecosystems.- 2. Transforming plantation forests to meet multifunctional objectives: lessons from British and Chinese experience.- 3. Forests for all? Considering the conservation implications of human-species interactions in the context of multifunctional forestry.- 4. Human engagement with forest environments – implications for physi-cal and mental health and wellbeing.- 5. Sustain-able Forest Management in China: Achievements in the Past and Challenges Ahead.- 6. The Value of Forest: An Ecological Economic Examination of People’s Perspective.- PART 2. Forest Resources Worldwide.- 7. Global trends and outlook for forest resources.- 8. Save the Forests : Use more wood.- PART 3. Forests, Forestry and Climate Change.- 9. Forests in the global carbon cycle.- 10. Forests, Forestry and Climate Change.- 11. Insect invasions and climate change in forest ecosys-tems.- PART 4. The Economics of Forestry.- 12. How cost-effective is forestry for climate change mitigation?.- 13. Additionality of climate change mitigation activities.- 14. Different Economic Approaches to Forest Management.- PART 5. Tree Breeding & Commercial Forestry.- 15. A Roadmap to Eucalyptus Breeding for Clonal Forestry.- 16. Conifer Somatic Embryogenesis and Multi-varietal Forestry.- 17. Modern Advances in Tree Breeding.- 18. A reality check in population management.- 19. Seed orchards and aspects on supporting tree breeding. [...]

Fields of interestForestry; Climate Change; Conservation Biology/Ecology

Target groupsUpper undergraduate


Due September 2013

2013. Approx. 600 p. 120 illus. in color. (Forestry Sciences, Volume 81) Hardcover7 * € (D) 181,89 | € (A) 186,99 | sFr 226,507 € 169,99 | £153.00ISBN 978-94-007-7075-1

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C. M. Gomes, Universidade Nova de Lisboa (UNL) Instituto Tecnologia Quimica e Biologica, Oeiras, Portugal; P. F. Faisca, Universidade de Lisboa, Lisbon, Portugal

Protein FoldingAn Introduction

This snapshot volume is designed to provide a smooth entry into the field of protein folding. Presented in a concise manner, each section introduces key concepts while providing a brief overview of the relevant literature. Outlook sub-sections will pinpoint specific aspects related to emerging methodologies, concepts and trends.

Features 7 Provides a snapshot of the field of protein fold-ing 7 Presents a unique resource for newcomers to the field 7 Indicates further reading from the current literature

Contents From the Contents: Energetics of Protein Folding: why proteins fold into stable conformations?.- Protein stability: how is the folded conforma-tion maintained?.- Protein Folding Kinetics and mechanisms: how do proteins fold?.- Protein misfolding and aggregation.- Protein aggregation, aggresomes and inclusion bodies.

Fields of interestProtein Science; Bioorganic Chemistry; Protein Structure



Due September 2013

2013. 100 p. 30 illus., 10 in color. Softcover7 approx. * € (D) 53,45 | € (A) 54,95 | sFr 66,507 approx. € 49,95 | £44.99ISBN 978-3-319-00881-3

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S. Gursky-Doyen, N. B. Grow, A. Krzton, Texas A&M University, College Station, TX, USA (Eds)

High Altitude PrimatesContents High Altitude Prosimian Primates.- 1. Effects of Altitude on the Conservation Biogeogra-phy of Lemurs in South East Madagascar.- 2. Hibernation patterns of dwarf lemurs in the high altitude forests of eastern Madagascar.- 3. Altitudinal Distribution and Ranging Patterns of Pygmy Tarsiers (Tarsius pumilus).- High Altitude Monkeys.- 4. Biogeography and conservation of Andean primates in Peru.- 5. Population density and ecological traits of high land woolly mon-keys at Cueva de los Guacharos National Park, Colombia.- 6. Seed Dispersal by Woolly Monkeys in Cueva de los Guacharos National Park (Colom-bia): An amazonian primate dispersing montane plants.- 7. Distribution and ecology of the most tropical of the high-elevation montane colobines: the ebony langur on Java.- 8. Snow tolerance of Japanese macaques inhabiting high-latitude mountainous forests of Japan.- 9. Seasonal and altitudinal migration of Japanese macaques in the Northern Japan Alps.- 10. Rhinopithecus bieti at Xiaochangdu, Tibet: Adaptations to a marginal environment.- 11. Nutritional implications of the high-elevation lifestyle of Rhinopithecus bieti.- 12. Variation in primate abundance along an eleva-tional gradient in the Udzungwa.- 13. Deriving Conservation Status for a High Altitude Popula-tion: Golden Monkeys of Mgahinga Gorilla National Park, Uganda.- High Altitude Apes.- 14. High Altitude Diets: Implications for the Feeding and Nutritional Ecology of Mountain Gorillas.- 15. Preliminary data on the highland Sumatran orangutans (Pongo abelii) of Batang Toru. [...]

Fields of interestConservation Biology/Ecology; Evolutionary Biol-ogy; Animal Ecology

Target groupsGraduate


Due August 2013

2013. XXIII, 501 p. 61 illus., 2 in color. (Developments in Primatology: Progress and Prospects, Volume 44) Hardcover7 * € (D) 139,09 | € (A) 142,99 | sFr 173,507 € 129,99 | £117.00ISBN 978-1-4614-8174-4

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122

K. R. Hakeem, University Putra Malaysia, Malaysia; R. U. Rehman, I. Tahir, University of Kashmir, India (Eds)

Plant signaling: Understanding the molecular cross-talkContents 1. Plant signaling: response to reactive oxygen spe-cies.- 2. SNARE proteins as signalling elements.- 3. Plant Rab GTPases in membrane trafficking and signaling.- 4.”PtdIns4P and PtdIns(4,5)P2 as sig-nalling phosphoinositides involved in tip growth “.- 5. Sugar signaling in plant growth and develop-ment.- 6. Nitrogen regulation and signalling in plants.- 7. “Phosphorus deficiency in plants: responses, adaptive mechanisms and signaling”.- 8. Reactive oxygen species-associated mechanism of acclamatory stress tolerance, signaling and redox-regulated gene expression in plants.- 9. Cyclic nucleotide gated channels-Essential signalling components in plants for fertilization and immu-nity responses.- 10. Signaling in response to cold stress.- 11. Cell Signaling during Drought and Salt Stress.- 12. Heat signaling and stress responses in photosynthesis.- 13. Senescence: Regulation and Signaling.- 14. Molecular builders of cell walls of Lignocellulosic feedstock: a source for biofu-els.- 15. Recent Trends in Jasmonate Signaling Pathway.- 16. Salicylic acid signaling.- 17. Ethylene signaling in plants- introspection.- 18. Plant, Mycorrhizal fungi and bacterial network.- 19. Self-Incompatibility patterns and signal transduc-tion.- 20. Plant Disease Resistance genes: From perception to signal transduction.

Fields of interestPlant Biochemistry; Plant Sciences; Cytokines and Growth Factors



Due September 2013

2013. XIV, 318 p. 56 illus., 42 in color. Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-81-322-1541-7

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G. R. Hicks, University of California, Riverside, CA, USA; S. Robert, Swedish University of Agricultural Sciences (SLU), Umeå, Sweden (Eds)

Plant Chemical GenomicsMethods and Protocols

Contents Fully-automated Compound Screening in Arabidopsis thaliana Seedlings.- Time-profiling Fluorescent Reporters in the Arabidopsis Root.- Screening for Bioactive Small Molecules by in vivo Monitoring of Luciferase-based Reporter Gene Expression in Arabidopsis thaliana.- Application of Yeast-two Hybrid Assay to Chemical Genomic Screens: A High-throughput System to Identify Novel Molecules Modulating Plant Hormone Receptor Complexes.- High-throughput Screening of Small Molecule Libraries for Inducers of Plant Defense Responses.- Using a Reverse Genetics Ap-proach to Investigate Small Molecule Activity.- In-vestigating the Phytohormone Ethylene Response Pathway by Chemical Genetics.- Screening for Inhibitors of Chloroplast Galactolipid Synthesis Acting in membrano and in Planta.- Forward Chemical Screening of Small RNA Pathways.- Identification and Use of Fluorescent Dyes for Plant Cell Wall Imaging Using High-Throughput Screening.- High-throughput Identification of Chemical Endomembrane Cycling Disruptors Uti-lizing Tobacco Pollen.- Plant Chemical Genomics: Gravity Sensing and Response.- Screening Chemi-cal Libraries for Compounds that Affect Protein Sorting to the Yeast Vacuole.- The use of Multi-drug Approach to Uncover New Players of the Endomembrane System Trafficking Machinery.- Cheminformatic Analysis of High-Throughput Compound Screens.- Endomembrane Dissection Using Chemically-Induced Bioactive Clusters.- Statistical Molecular Design: A Tool to Follow Up Hits From Small Molecule Screening. [...]

Fields of interestPlant Sciences; Plant Genetics & Genomics



Due August 2013

2013. 230 p. 42 illus., 13 in color. (Methods in Molecular Biology, Volume 1056) Hardcover7 * € (D) 101,64 | € (A) 104,49 | sFr 126,507 € 94,99 | £85.50ISBN 978-1-62703-591-0

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M. D. Hirschey, Duke University Medical Center, Durham, NC, USA (Ed)

SirtuinsMethods and Protocols

Contents Introduction: Sirtuins in Aging and Diseases.- Sir-tuins in Yeast: Phenotypes and Tools.- Studying the C. elegans Sirtuins.- Genetic and Biochemi-cal Tools for Investigating Sirtuin Function in Drosophila melanogaster.- Generating Mam-malian Sirtuin Tools for Protein-Interaction Analysis.- Mass Spectrometry-Based Detection of Protein Acetylation.- SILAC-Based Quantification of Sirt1-Responsive Lysine Acetylome.- Targeted Quantitation of Acetylated Lysine Peptides by Selected Reaction Monitoring Mass Spectrom-etry.- Identification of Deacetylase Substrates with the Biotin Switch Approach.- Assaying Chromatin Sirtuins.- Measurement of Sirtuin Enzyme Activity Using a Substrate-Agnostic Fluorometric Nicotin-amide Assay.- Detecting Sirtuin-Catalyzed Deac-ylation Reactions Using 32P-Labeled NAD and Thin-Layer Chromatography.- Chemical Acetyla-tion And Deacetylation.- Accurate Measurement of Nicotinamide Adenine Dinucleotide (NAD+) with High-Performance Liquid Chromatogra-phy.- In Vivo Measurement of the Acetylation State of Sirtuin Substrates as a Proxy for Sirtuin Activity.- Oxygen Flux Analysis to Understand the Biological Function of Sirtuins.- The Emerging Links Between Sirtuins and Autophagy.- Methods to Study the Role of Sirtuins in Genome Stability.- Circadian Measurements of Sirtuin Biology.- Uti-lizing Calorie Restriction to Evaluate the Role of Sirtuins in Healthspan and Lifespan of Mice.

Fields of interestAnimal Genetics and Genomics; Proteomics



Due September 2013

2013. X, 338 p. 69 illus., 36 in color. (Methods in Molecular Biology, Volume 1077) Hardcover7 * € (D) 117,69 | € (A) 120,99 | sFr 146,507 € 109,99 | £99.00ISBN 978-1-62703-636-8

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123

S. H. Howell, Ames, IA, USA (Ed)

Molecular BiologyThe aim of this project is to produce a the world’s most comprehensive reference in plant sciences.

Features 7 Available in both print and online 7 The online text will be regularly updated to enable the reference to remain a useful authoritative resource

Contents Control of transcription (incl miRNA).- Control of translation.- Macromolecular structures (car-bohydrates, proteins etc).- Enzyme function and enzyme-enzyme interactions.- Photosynthesis.- Primary metabolism.- Natural products chemistry (secondary metabolism).- Proteomics.- Metabolo-mics.- Synthetic biology.

Fields of interestPlant Genetics & Genomics; Plant Biochemistry; Plant Sciences


Product categoryReference work

Due March 2014

Print

2014. 1000 p. 450 illus. in color. (The Plant Sciences, Volume 2) 7 approx. * € (D) 533,93 | € (A) 548,90 | sFr 664,507 approx. € 499,00 | £449.50ISBN 978-1-4614-7569-9

9<HTMERB=ehfgjj> eReference

2014. 7 approx. ** € (D) 593,81 | € (A) 598,80 | sFr 698,007 approx. € 499,00 | £449.50ISBN 978-1-4614-7570-5

9<HTMERB=ehfhaf> Print + eReference

2014. 1000 p. 450 illus. in color. (The Plant Sciences, Volume 2) 7 approx. * € (D) 667,68 | € (A) 686,40 | sFr 831,007 approx. € 624,00 | £562.00ISBN 978-1-4614-7571-2

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A. G. Kutikhin, Kemerovo State Medical Academy, Russia; A. E. Yuzhalin, Russian Academy of Medical Sciences, Kemerovo, Russia

Genomics of Pattern Recognition ReceptorsApplications in Oncology and Cardiovascular Diseases

This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases.

Features 7 Summarizes the field and indicates key direc-tions 7 Explores and analyzes genomic varia-tions 7 With numerous tables presenting the data systematically

Contents The Biology of Toll-like Receptors and NOD-like Receptors: Toggles of Inflammation.- Pattern Recognition Receptors, Gene Polymorphisms, and Cancer: A Double-Edged Sword.- Structural Genomic Variation in Toll-Like Receptor 4 and Cancer.- Structural Genomic Variation in Other Toll-like Receptors and Cancer.- Structural Ge-nomic Variation in Toll-Like Receptor Signaling Pathway and Cancer.- Structural Genomic Varia-tion in Toll-like Receptor Pathway and Prostate Cancer.- Structural Genomic Variation in NOD-Like Receptors and Cancer.- Structural Genomic Variation in Pattern Recognition Receptors and Cardiovascular Diseases.- Hot Spots In the Field: Where Should We Go.

Fields of interestReceptors; Immunology; Cancer Research



Due July 2013

2013. VIII, 287 p. 2 illus., 1 in color. Hardcover7 * € (D) 149,79 | € (A) 153,99 | sFr 186,507 € 139,99 | £126.00ISBN 978-3-0348-0687-9

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E. Lichtfouse, INRA-CMSE-PME, Dijon, France (Ed)

Sustainable Agriculture ReviewsVolume 13

Sustainable agriculture is a rapidly growing field aiming at producing food and energy in a sustain-able way for humans and their children. It is a discipline that addresses current issues: climate change, increasing food and fuel prices, poor-nation starvation, rich-nation obesity, water pol-lution, soil erosion, fertility loss, pest control and biodiversity depletion. This series gathers review articles that analyze current agricultural issues and knowledge, then proposes alternative solutions.

Features 7 Presents safe techniquest to preserve stored grains 7 Lists biopesticides produced by plants 7 Review methods to control ants

Contents Leaf-cutting ants, biology and control.- Impact of pesticide productivity on food security.- Farmland birds and arable farming, a meta-analysis.- Phy-toremediation, transgenic plants and microbes.- Management of pathogens of stored cereal grains.- Allelopathy for pest control.- Rice bed planting and foliar fertilization.- Integrated nutrient man-agement and postharvest of crops.- Intercropping taro and bambara groundnut.- Land productivity and food security in Zhangjiagang, China.

Fields of interestLife Sciences, general; Agriculture; Sustainable Development


Product categoryReviews

Due August 2013

2014. X, 306 p. 64 illus., 56 in color. (Sustainable Agriculture Reviews, Volume 13) Hardcover7 * € (D) 149,79 | € (A) 153,99 | sFr 186,507 € 139,99 | £126.00ISBN 978-3-319-00914-8

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124

R. Ming, University of Illinois, Urbana, IL, USA; P. H. Moore, Hawaii Agriculture Research Center, Waipahu, HI, USA (Eds)

Genetics and Genomics of PapayaFeatures 7 Provides the latest information on papaya genetics and genomics for papaya researchers and plant biologists 7 Written by a team of experts in various aspects of papaya genomics 7 Features numerous color illustrations and photographs

Contents Papaya (Carica papaya L.): Origin, Domestica-tion, and Production.- Biology of the Papaya Plant.- Phenotypic and Genetic Diversity of Papaya.- Vasconcellea for Papaya Improvement.- The Phylogeny of the Caricaceae.- History and Future of the Solo Papaya.- Hawaii’s Transgenic Papaya Story 1978-2012: A Personal Account.- Molecular Genetic Mapping of Papaya.- Molecular Cytogenetics of Papaya.- Physical Map of Papaya Genome.- Sequencing and Assembly of the Trans-genic Papaya Genome.- Syntenic Sequence Con-servation Between and Within Papaya Genes.- Pa-paya Repeat Database.- Genomics of Papaya Fruit Development and Ripening.- Genomics of Papaya Disease Resistance.- Genomics of Papaya Sex Chromosomes.- Physical Mapping of Papaya Sex Chromosomes.- Cloning Major Genes Controlling Fruit Flesh Color in Papaya.- Molecular Markers in Papayas.- Papaya Nutritional Analysis.- Papaya as a Medicinal Plant.- Allele Discovery Platform (ADP) in Papaya (Carica papaya L.).

Fields of interestPlant Sciences; Plant Biochemistry; Plant Anato-my/Development



Due August 2013

2014. XX, 695 p. 73 illus., 61 in color. (Plant Genetics and Genomics: Crops and Models, Volume 10) Hardcover7 * € (D) 181,89 | € (A) 186,99 | sFr 226,507 € 169,99 | £153.00ISBN 978-1-4614-8086-0

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Nucleic Acids and Molecular BiologySeries editor: J. M. Bujnicki

Volume 29

J. KJEMS, E. Ferapontova, K. V. Gothelf, Aarhus University, Denmark (Eds)

Nucleic Acid NanotechnologyThis volume on nucleic acid nanotechnology of-fers authoritative, up-to-date and comprehensive coverage of nanotechnological studies and applica-tions of nucleic acids.

Features 7 Provides up-to-date comprehensive coverage on nanotech studies of nucleic acids 7 High-lights future applications of nucleic acid nanotech-nology 7 Written by leading experts in the field

Contents Self-assembly of DNA bases via hydrogen bonding studied by Scanning tunneling microscopy.- Force spectroscopy of DNA and RNA: structure and kinetics from single molecule experiments.- The power of single molecule FRET microscopy applied to DNA nanotechnology.- DNA nano-structures: DNA Tiles.- DNA Origami.- DNA nanotechnology: From biology and beyond.- DNA Templated Synthesis.- Mechanical DNA devices.- Nano-encapsulation of Oligonucleotides for Therapeutic Use.- Cell-specific aptamers for nano-medical applications.- Nucleic acid sequenc-ing and analysis with nanopores.- Application of Nanomaterials For DNA Sensing.

Fields of interestNucleic Acid Chemistry; Nanochemistry; Gene Expression



Due September 2013

2013. XI, 302 p. 119 illus., 112 in color. Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-3-642-38814-9

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A. (. Ostrovsky, University of Vienna, Austria

Evolution of Sexual Reproduction in Marine InvertebratesExample of gymnolaemate bryozoans

Features 7 Comparative analysis of reproductive patterns in Bryozoa 7 Structural diversity, independent origin, brood chamber evolution in different cheilostome groups 7 Analyses main direc-tions in bryozoans sexual reproduction evolu-tion 7 Emerging trends of these are compared with analogues in evolution of bryozoan order Ctenostomata and other marine invertebrate groups 7 Reconstruction of stages of sexual reproduction evolution in other bryozoan groups 7 History reviews of study of sexual reproduction in the Gymnolaemata with list of species studied

Contents Chapter 1. Reproductive patterns of gymnolae-mate Bryozoa: general overview and comparative analysis.- Chapter 2. Cheilostome brood chambers — structure, formation, evolution.- Chapter 3. Evolution of reproductive patterns in Cheilosto-mata.- Appendix I: History of research on sexual reproduction in gymnolaemate Bryozoa.- Appen-dix II: Materials, methods and list of Taxa studied.

Fields of interestFreshwater & Marine Ecology; Evolutionary Biol-ogy; Zoology



Due August 2013

2013. X, 450 p. 102 illus., 10 in color. Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-94-007-7145-1

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125

L. Porter-Bolland, Instituto de Ecología, A. C., Xalapa, Mexico; I. Ruiz-Mallén, Institute of Environmental Science and Technology, Bellaterra, Barcelona, Spain; C. Camacho-Benavides, Global Diversity Foundation, Xalapa, Mexico; S. R. McCandless, Global Diversity Foundation, Bristol, VT, USA (Eds)

Community Action for ConservationMexican Experiences

Contents Introduction: Biocultural diversity and the partici-pation of local communities in national and global conservation.- Community conservation and ethnoecology: the three dimensions of local-level biodiversity maintenance.- Conservation and for-est communities in Mexico: Experiences, visions and rights.- Community Conservation Experienc-es in Three Ejidos of the Lower Balsas River Basin, Michoacan.- Challenges in ICCA governance: the case of El Cordon del Reten in San Miguel Chima-lapa, Oaxaca.- Local perceptions of conservation initiatives in the Calakmul region.- Community conservation in Punta Laguna: a case of adaptive ecotourism management.- Local participation in community conservation: Methodological contributions.- Community-based biodiversity monitoring in Mexico: Current status, challenges and future strategies for collaboration with scien-tists.- Drawing analysis: tools for understanding children’s perceptions of community conserva-tion.- Conclusions.

Fields of interestPlant Sciences; Environmental Management; Nature Conservation



Due August 2013


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D. Praticὸ, Temple University, Philadelphia, PA, USA; P. Mecocci, Università degli Studi di Perugia, Italy (Eds)

Studies on Alzheimer’s DiseaseFeatures 7 Reviews the basic science and clinical knowledge of the role of free radicals and anti-oxidants 7 Describes the most current diag-nostic tools , laboratory methods and technol-ogy 7 Provides specific coverage on emerging technology and medical applications

Contents Section 1: Hypotheses.- Oxidative stress: impact in neuroscience research.- Oxidative stress and Alzheimer’s disease.- Inflammation and Oxida-tion: a link in Alzheimer’ disease pathogenesis.- GAPDH:β-amyloid mediated iron accumulation in Alzheimer’s disease.- Aβ in mitochondria: one piece in the Alzheimer’s disease puzzle.- The role of the plasma membrane redox system in the pathognesis of Alzheimer’s disease.- Section 2: Mechanisms.- Metal dysfunction in Alzheimer’s disease.- Brain Oxidative Stress in the Patho-genesis and Progression of Alzheimer’s Disease.- Cholesterol metabolism and oxidative stress in Alzheimer’s disease.- Brain hypometabolism, oxidative stress, maternal transmission and risk of late-onset Alzheimer’s disease.- Stress and HPA axis dysfunction in Alzheimer’s disease.- Section 3: Clinics.- Diabetes mellitus and its impact on sporadic Alzheimer’s disease.- Peripheral bio-markers of oxidative tress in Alzheimer’s disease.- Nutrition lifestyle and oxidative stress: prevention in Alzheimer’s disease.- Are antioxidants food and nutrients useful in preventing cognitive de-cline?.- Antioxidant clinical trials in Mild Cogni-tive Impairment and Alzheimer’s disease.

Fields of interestOxidative Stress; Cell Biology; Geriatrics/Geron-tology



Due August 2013

2014. XIII, 300 p. 26 illus., 22 in color. (Oxidative Stress in Applied Basic Research and Clinical Practice) Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-1-62703-597-2

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Progress in BotanyGenetics - Physiology - Systematics - Ecology

U. Lüttge, Series editors: W. Beyschlag, J. Cushman, M. Weigend

Volume 75

U. Lüttge, Technical University Darmstadt, Germany; W. Beyschlag, University of Bielefeld, Germany; J. Cushman, University of Nevada, Reno, NV, USA (Eds)

Progress in BotanyVol. 75

Features 7 Up-to-date reviews 7 Written by leading experts 7 All contributions are peer-reviewed

Contents Ants, Plants and Fungi: A view on some patterns of interaction and diversity.- ABA as a Universal Plant Hormone.- Reduced genomes from parasitic plant plastids: templates for minimal plastomes? Nucleotides and nucleosides: transport, metabo-lism and signaling function of extracellular ATP.- Regulation of PPi Levels Through the Vacuolar Membrane H+-pyrophosphatase.- Interactions Between Nutrients and Crassulacean Acid Metab-olism.- Guttation: Quantification, Microbiology and Implications for Phytopathology.- Adaptation of rice to flooded soils.- Physiological mechanisms of flooding tolerance in rice: transient complete submergence and prolonged standing water between 0.3 to over 3 m.- Beyond Mutualism: Complex Mycorrhizal Interactions.- Ecology of Phreatophytes.- Some like it hot - are desert plants indifferent to climate change?

Field of interestPlant Sciences



Due August 2013

2014. XII, 428 p. 46 illus., 24 in color. Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-3-642-38796-8

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126

C. A. Rebeiz, Rebeiz Foundation for Basic Research, Champaign, IL, USA

Chlorophyll Biosynthesis and Technological ApplicationsContents Dedication.- Preface.- Author Biography.- 1. Some Major Steps in the Understanding of the Chem-istry and Biochemistry of Chl.- 2. Synopsis.- 3. Development of Analytical and Preparatory Tech-niques.- 4. Development of Cell-free Systems.- 5. Reactions between δ-Aminolevulinic Acid and Protoporphyrin IX.- 6. The Iron and Magnesium Branches of the Porphyrin Biosynthetic Path-way.- 7. The Chl a Carboxylic Biosynthetic Routes: Reactions between Mg-Protoporphyrin IX and Protochlorophyllide a.- 8. The Chl a Carboxylic Biosynthetic Routes: Protochlorophyllide a.- 9. The Chl a Carboxylic Biosynthetic Routes: (Photo)Conversion of Protochlorophyllides (Pchlides) a to Chlorophyllide (Chlide) a.- 10. The Chl a Carboxylic Biosynthetic Routes: Conversion of Chlide a to Chl a.- 11. The Fully Esterified Chlo-rophyll a Biosynthetic Routes: Reactions between Mg-Protoporphyrin IX Diester and Chl a.- 12. The Chlorophyll b Biosynthetic Pathway: Novel Meta-bolic Intermediates.- 13. The Chl b Biosynthetic Pathway: Intermediary Metabolism.- 14. Relation-ship of Chlorophyll Biosynthetic heterogeneity to the Greening Group affiliation of Plants.- 15. Relationship of Chlorophyll biosynthesis to the Assembly of Chlorophyll-Protein Complexes.- 16. The Chlorophyll Biosynthetic Heterogeneity and Chloroplast Bioengeneering.- 17. Photodynamic Herbicides.- 18. Photodynamic Insecticides.- 19. ALA-Dependent Cancericides.- Appendix I. Sequenced Chlorophyll Biosynthetic Enzymes.- Appendix II. Sequenced Apoproteins of the Chloroplast Pigment-Protein Complexes.

Fields of interestBiochemistry, general; Plant Physiology; Biophys-ics and Biological Physics

Target groupsUpper undergraduate


Due August 2013


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R. J. Rose, The University of Newcastle, Callaghan, NSW, Australia (Ed)

Legume GenomicsMethods and Protocols

Contents The Model Legume Genomes.- Fluorescent In Situ Hybridization (FISH) on Pachytene Chromosomes as a Tool for Genome Characterization.- Targeted Mutagenesis for Functional Analysis of Gene Duplication in Legumes.- RNA-Seq for Transcrip-tome Analysis in Non-Model Plants.- Functional Analysis of Legume Genome Arrays.- Genome-Wide Identification of MicroRNAs in Medicago truncatula by High-Throughput Sequencing.- De-termining Abundance of MicroRNAs and Other Small RNAs in Legumes.- Forward Genetics Screening of Medicago truncatula Tnt1 Insertion Lines.- Reverse Genetics in Medicago truncatula Using a TILLING Mutant Collection.- High-Throughput and Targeted Genotyping of Lotus japonicus LORE1 Insertion Mutants.- Isolation and Forward Genetic Analysis of Developmental Genes in Pea.- Gene Silencing in Medicago trun-catula Roots Using RNAi.- Molecular Markers for Genetics and Plant Breeding: The MFLP Marker System and Its Application in Narrow-Leafed Lupin (Lupinus angustifolius).- Stable Transfor-mation of Medicago truncatula cv. Jemalong for Gene Analysis Using Agrobacterium tumefaciens.- Transient Gene Expression in Medicago trun-catula Leaves Via Agroinfiltration.- Subcellular Localization of Transiently-Expressed Fluorescent Fusion Proteins.- Proteomics and the Analysis of Nodulation.- Phosphoproteomic Analysis of Pep-tides.- Plant Metabolomics: From Experimental Design to Knowledge Extraction.

Fields of interestPlant Sciences; Plant Genetics & Genomics; Gene Function



Due August 2013

2013. XVI, 376 p. 42 illus., 24 in color. (Methods in Molecular Biology, Volume 1069) Hardcover7 * € (D) 117,69 | € (A) 120,99 | sFr 146,507 € 109,99 | £99.00ISBN 978-1-62703-612-2

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J. J. Sanchez-Serrano, J. Salinas, CSIC, Madrid, Spain (Eds)

Arabidopsis ProtocolsContents Handling Arabidopsis Plants: Growth, Preser-vation of Seeds, Transformation and Genetic Crosses.- Using Arabidopsis Related Model Spe-cies (ARMS): Growth, Genetic Transformation and Comparative Genomics.- Growing Arabidop-sis in vitro: Cell Suspensions, in vitro Culture, and Regeneration.- Arabidopsis Database and Stock Resources.- Bioinformatic Tools in Arabidopsis Research.- Exploiting Natural Variation in Arabi-dopsis.- Grafting in Arabidopsis.- Agrobacterium tumefaciens Mediated Transient Transformation of Arabidopsis thaliana Leaves.- iTilling: Personal-ized Mutation Screen.- Tailor Made Mutations in Arabidopsis Using Zinc-Finger Nucleases.- The Use of Artificial Micro RNA Technology to Control Gene Expression in Arabidopsis thaliana.- Generation and Identification of Arabidopsis EMS Mutants.- Generation and Identification of Arabidopsis T-DNA Insertion Mutants.- Identifi-cation of EMS-induced Causal Mutations in Ara-bidopsis thaliana by Next-Generation Sequenc-ing.- Arabidopsis Transformation with Large Bacterial Artificial Chromosomes.- Global DNA Methylation Analysis Using Methyl-Sensitive Amplification Polymorphism (MSAP).- Next Gen-eration Mapping of Genetic Mutations Using Bulk Population Sequencing.- Chemical Fingerprinting of Arabidopsis Using Fourier-transform Infrared (FT-IR) Spectroscopic Approaches.- A Pipeline for 15N Metabolic Labeling and Phosphoproteome Analysis in Arabidopsis thaliana.- Gene Expres-sion Profiling Using DNA Microarrays.- Forward Chemical Genetic Screening.- Highly-Reproduc-ible ChIP-On-Chip Analysis to Identify Genome-Wide Protein Binding and Chromatin Status in Arabidopsis thaliana. [...]

Fields of interestPlant Genetics & Genomics; Gene Expression



Due August 2013

3rd ed. 2013. XX, 700 p. 102 illus., 70 in color. (Methods in Molecular Biology, Volume 1062) Hardcover7 * € (D) 133,74 | € (A) 137,49 | sFr 166,507 € 124,99 | £112.50ISBN 978-1-62703-579-8

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127

H. Schatten, University of Missouri-Columbia, MO, USA (Ed)

Cell and Molecular Biology of Breast CancerContents 1. Histopathology and grading of breast cancer.- 2. Multicentric/multifocal breast cancer: overview, biology and therapy.- 3. The immune system in breast cancer initiation and progression: role of epithelial to mesenchymal transition.- 4. Remodel-ing of the extracellular matrix: implications for cancer.- 5. Biology and treatment of basal-like breast cancer.- 6. Re-excision after lumpectomy for breast cancer.- 7. Novel anti-angiogenic therapies using naturally-occurring and synthetic drugs to combat progestin-dependent breast cancer.- 8. New insights on estrogen receptor actions in hor-mone-responsive breast cancer cells by interaction proteomics.- 9. Reprogramming breast cancer cells with embryonic microenvironments: insights from nodal signaling.- 10. Metastatic determinants: breast tumour cells in circulation.- 11. Breast can-cer epigenetics: biomarkers and therapeutic poten-tial.- 12. The impact of centrosome abnormalities on breast cancer development and progression with a focus on targeting centrosomes for breast cancer therapy.- 13. A New Perspective on Cyclin D1: beyond cell cycle regulation.- 14. Gene sig-natures of inflammatory breast cancer: epithelial plasticity and a cancer stem cell phenotype.- 15. An integrated human mammary epithelial cell culture system for studying carcinogenesis and aging.- 16. New breast cancer treatment consid-erations – a brief review of the use of genetically modified (attenuated) bacteria as therapy for advanced and metastatic breast cancer.

Fields of interestCell Biology; Biological Microscopy; Cancer Research



Due September 2013

2013. XII, 424 p. 55 illus., 51 in color. Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-1-62703-633-7

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K. Touhara, The University of Tokyo, Japan (Ed)

Pheromone SignalingMethods and Protocols

Contents Female Moth Pheromones.- Pheromones in the Fruit Fly.- Analysis of Volatile Mouse Pheromones by Gas Chromatography Mass Spectrometry.- Murine Non-Volatile Pheromones: Isolation of Exocrine-Gland Secreting Peptide 1.- Chemical Analysis of Aquatic Pheromones in Fish.- Analy-sis of Ascarosides from Caenorhabditis elegans Using Mass Spectrometry and NMR Spectros-copy.- Identification of Chemosensory Receptor Genes from Vertebrate Genomes.- Functional Assays for Insect Olfactory Receptors in Xenopus Oocytes.- A Protocol for Heterologous Expres-sion and Functional Assay for Mouse Pheromone Receptors.- Genetic Manipulation to Analyze Pheromone Responses: Knockouts of Multiple Receptor Genes.- Electro-Antennogram and Single Sensillum Recording in Insect Antennae.- Calcium Imaging of Pheromone Responses in the Insect Antennal Lobe.- Live Cell Calcium Imaging of Dissociated Vomeronasal Neurons.- Whole Mount Imaging of Responses in Mouse Vomero-nasal Neurons.- Calcium Imaging of Vomeronasal Organ Response Using Slice Preparations from Transgenic Mice Expressing G-CaMP2.- The Electrovomeronasogram: Field Potential Record-ings in the Mouse Vomeronasal Organ.- Electrical Recordings from the Accessory Olfactory Bulb in VNO-AOB Ex Vivo Preparations.- Pheromone-Induced Expression of Immediate Early Genes in the Mouse Vomeronasal Sensory System.- Insect Pheromone Behavior: Fruit Fly.- Quantitative Assessment of Pheromone-Induced Dauer Forma-tion in Caenorhabditis elegans.- Acute Behavioral Responses to Pheromones in C. elegans (Adult Behaviors: Attraction, Repulsion).- Behavioral Analysis of Pheromones in Fish. [...]

Fields of interestCell Biology; Endocrinology; Receptors



Due August 2013

2013. 395 p. 73 illus., 15 in color. (Methods in Molecular Biology, Volume 1068) Hardcover7 * € (D) 117,69 | € (A) 120,99 | sFr 146,507 € 109,99 | £99.00ISBN 978-1-62703-618-4

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K. Turksen, Ottawa Hospital Research Institute, ON, Canada (Ed)

Stem Cell NanotechnologyMethods and Protocols

Features 7 Includes cutting-edge methods and protocols for nanotechnological approaches to stem cell bi-ology 7 Provides step-by-step detail essential for reproducible results 7 Contains key notes and implementation advice from the experts

Contents Propagation and Differentiation of Human Wharton’s Jelly Stem Cells on Three Dimensional Nanofibrous Scaffolds.- Composite Electrospun Nanofibers for Influencing Stem Cell Fate.- In Vitro Nanoparticle-Mediated Intracellular Delivery into Human Adipose-Derived Stem Cells.- Screening of Nanoparticle Embryotoxicity Using Embryonic Stem Cells.- Peptide Nanofiber Scaffolds for Multipotent Stromal Cell Cultur-ing.- Patterned Polymeric Surfaces to Study the Influence of Nanotopography on the Growth and Differentiation of Mesenchymal Stem Cells.- Transduction of Murine Embryonic Stem Cells by Magnetic Nanoparticle-Assisted Lentiviral Gene Transfer.- Lanthanide-Based Upconversion Nanoparticles for Connexin-Targeted Imaging in Co-Cultures.- Basic Protocols to Investigate hMSC Behavior onto Electrospun Fibers.- General Pro-tocol for the Culture of Cells on Plasma-Coated Electrospun Scaffolds.- Mesenchymal Stem Cells and Nano-Structured Surfaces.- Chondrogenic Differentiation of Menstrual Blood-Derived Stem Cells on Nanofibrous Scaffolds.- Engineering of a 3D Nanostructured Scaffold Made of Functional-ized Self-Assembling Peptides and Encapsulated Neural Stem Cells.

Fields of interestCell Biology; Stem Cells



Due July 2013

2013. 180 p. 36 illus., 10 in color. With online files/update. (Methods in Molecular Biology, Volume 1058) Hardcover7 * € (D) 101,64 | € (A) 104,49 | sFr 126,507 € 94,99 | £85.50ISBN 978-1-62703-570-5

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128

K. Turksen, Ottawa Hospital Research Institute, ON, Canada (Ed)

Stem Cells: Current Challenges and New DirectionsFeatures 7 Provides a state-of-the-science look at Stem Cells, addressing the current challenges, and discussing future directions 7 Comprehensively covers topics that will be relevant to both research and clinical applications 7 The assembled contributors reflect international viewpoints and expertise and run the gamut from well-known to up-and-coming future stars

Contents Myogenic Potential of Stem Cells: In Vivo As-sessment.- Urine DerivedSstem Cells: Biological Characterization and Potential Clinical Applica-tions.- Immunoregulatory Properties of Mesen-chymal Stem Cells: In Vitro and in Vivo.- Current Research on Stem Cells in Parkinson’s Disease: Progress and Challenges.- Stem Cell Applications in Retinal Diseases.- Potential Use of Dental Stem Cells for Craniofacial Tissue Regeneration.- Pedi-atric Diseases and Stem Cells: Recent Advances and Challenges.- Stem Cell Therapy – From the Heart to the Periphery.- Stem Cells in Wound Healing.- Cancer Stem Cells: The Gist of the Mat-ter.- Filling the Gap in the Relationship Between Cancer and Stem Cells.- Therapy Resistance in Prostate Cancer: A Stem Cell Perspective.- Mecha-nisms of Somatic Cell Reprogramming.- Disease Modeling and Drug Discovery Using Human Pluripotent Stem Cells.- Stem Cell Research: Ethi-cal Considerations.

Fields of interestStem Cells; Cancer Research; Reproductive Medicine



Due September 2013

2013. Approx. 300 p. 22 illus., 12 in color. (Stem Cell Biology and Regenerative Medicine, Volume 33) Hardcover7 * € (D) 149,79 | € (A) 153,99 | sFr 186,507 € 139,99 | £126.00ISBN 978-1-4614-8065-5

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Y. Vodovotz, University of Pittsburgh, PA, USA; G. An, University of Chicago, IL, USA (Eds)

Complex Systems and Computational Biology Approaches to Acute InflammationContents An overview of the Translational Dilemma and the need for Translational Systems Biology of inflammation.- Part I: Complex Systems Methods and Applications.- Translational Equation-based Modeling.- Agent-based Modeling in Translation-al Systems Biology.- Analysis of Heart Rate Vari-ability.- Analysis of Ventilatory Pattern Variabil-ity.- Part II: Translational Modeling of Sepsis and Trauma.- Disorder of Systemic Inflammation in Sepsis and Trauma: A Systems Perspective.- Multi-scale equation-based models: Insights for Inflam-mation and Physiological Variability.- Integrating Data Driven and Mechanistic Models of the Inflammatory Response in Sepsis and Trauma.- In silico Trials and Personalized Therapy for Sepsis and Trauma.- Part III: Translational Modeling of Wound Healing.- Disorder of Localized Inflam-mation in Wound Healing: A Systems Perspec-tive.- Equation-based Models of Wound Healing and Collective Cell Migration.- Agent-based Models of Wound Healing.- Part IV: Translational Modeling of Host-pathogen Interactions.- Model-ing Host-Pathogen Interactions in Necrotizing Enterocolitis.- Modeling Host-Vector-Pathogen Immuno-inflammatory Interactions in Malaria.- Part V: Future Perspectives.- Translation to Imple-mentation.- The Rationale and Implementation of Translational Systems Biology as a new Paradigm for the Study of Inflammation.- Index.

Fields of interestSystems Biology; Immunology; Biomedicine general



Due August 2013

2014. XVI, 304 p. 56 illus., 29 in color. Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-1-4614-8007-5

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Q. Zhang, Huazhong Agricultural University, Wuhan, China; R. A. Wing, University of Arizona, Tucson, AZ, USA (Eds)

Genetics and Genomics of RiceThis book provides a comprehensive coverage of the advances in genetics and genomics research on rice.

Features 7 One of the most in-depth studies of rice genetics and genomics 7 Covers special topics pertaining to the rice genome, including the docu-mentation of tools and resources for functional analysis of the rice genome 7 Features numerous color illustrations and photographs

Contents A reference rice genome sequence in the 10K genome era.- The Wild Relative of Rice – Ge-nomes and Genomics.- Natural variation and sequencing-based genetics studies in rice.- Ge-nome mapping, markers and QTLs.- Trans-posable element dynamics in rice and its wild relatives.- Molecular cytogenetics of rice and its wild relatives.- Mutant resources for functional analysis of the rice genome.- Transcriptome profil-ing in rice.- Epigenomics of rice.- Non-coding regulatory RNAs.- Disease resistance.- Insect Resistance.- Abiotic stress resistance.- Nitrogen and Phosphorus Uptake and Utilization.- Yield.- Understanding Genetic Molecular Basis of Rice Grain Quality.- Advances in the Understanding of Genetic and Molecular Basis of Heterosis in Rice.- Flowering.- Panicle Development.- Root Develop-ment.- Reproductive isolation between indica and japonica subspecies.- Genomics-based breeding technology.- Utilization of Exotic Germplasm.- Transformation and transgenic breeding.

Fields of interestPlant Sciences; Plant Biochemistry; Plant Anato-my/Development



Due August 2013

2014. X, 726 p. 51 illus., 40 in color. (Plant Genetics and Genomics: Crops and Models, Volume 5) Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-1-4614-7902-4

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