Elbow Reconstruction Edit 01

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    Laboratory

    - CBC : normal

    - ESR : 29mm/h- SAP : 161 u/l (40 150)

    - LDH : 303 u/m (230460)

    Left elbow AP and lateral X-ray (January 2006) :

    - Blastic and lytic lesions in the left distal humerus

    - Periosteal reaction and soft tissue swelling

    After neoadjuvant chemotherapy

    tumor became more sclerotic & solid

    Chest X-Ray : no evidence of metastatic feature

    Bone scintigraphy : increased uptake only at the left elbow Neither showed no evidence of metastatic disease

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    CT scan :- Lytic-sclerotic lesion with irregular margin

    - Thickening of cortex and periosteal- New bone formation and good medullary cavity

    Cytology examination :

    Spindle cells, pleomorphic with osteoid positifPhoto 11

    Clinico Pathological Conference (CPC)

    - Diagnosed as conventional osteosarcoma neoadjuvant chemotherapy

    - Planned for limb salvage surgery using an extracorporeal irradiation of distal humerus

    First Stage :

    - Resection of the half distal humerus that contain tumor mass Pathology

    Anatomy Department

    - Osteotomy of olecranon

    - Conservation of n.radial, n.ulnar & muscle groups, except the part of the triceps& brachialis attached to the tumor mass

    - The resected humerus was sent to BATAN for irradiation with dose 30,000 rads

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    Second Stage :

    - Reconstruction of the half distal humerus with plate and screw

    - Olecranon fixation with TBW- Sutured common flexor & extensor origins to the original sites

    - Histological examination of the surgical specimen:

    So much residual viable tumor cells and the tumor classified as unresponder to the induction

    chemotherapeutic agents (HUVOS 1)

    -After surgery patient was planned to received adjuvant chemotherapy consisting of another

    agents

    SECOND CASE

    Local Status :

    Mass :

    - 32 cm in circumferential length (23 cm in the health tissue)- Firm, tenderness, fixed with ill-defined margin- No venectation

    Laboratory

    - CBC : normal

    - ESR 30 mm/h

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    - SAP 192 u/l (40150)

    - LDH : 165 u/m (230460)

    X-ray of left elbow AP and lateral views (May 2006) : heavily mineralized mass attached by broad base to the posterior

    aspect of left distal humerus and soft tissue swelling

    - Chest X-Ray : no evidence of metastatic feature

    - Bone scintigraphy : inceased uptake only at the left elbow

    No evidence of metastatic disease

    Review slide from first operation :

    Spindle cells, minimal cytologic atypia and rare mitoticfigure, osteoid positif

    Clinico Pathological Conference (CPC)

    - Diagnosed as reccurrent parosteal osteosarcoma

    - Planned to limb salvage procedure using extra corporealirradiation autograft

    - Death : Nov 2007

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    First Stage :

    - Resection of the half distal humerus and excision ofthe tumor mass sent to Pathology Anatomy Dep.

    - Resected humerus BATAN for irradiation 30,000rads

    Second Stage :

    - Reconstruction of the half distal humerus and elbow by fixed them into the

    proximal shaft with plate and screw

    - Olecranon was fixed with the tension band wire

    - Common flexor and extensor origins were sutered again to the original sites

    - Radiohumeral joint was fixed with the K wire for temporary

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    Post-operative X rays :Humeral shaft fixed with plate and screw and olecranon fixed with TBW

    Discussion- Primary malignant bone tumors rare lesions

    - Before 1970s routine management was consisted of transbone amputations or disarticulation

    dismal survival rate 10-20%

    Dahlins bone tumors general aspects and data on 11,087 cases.1996. pp.143-95.

    J Am Acad Orthop Surg 2003;11:25-37. hal. 24

    Development of :- Effective chemotherapeutic agents

    - CT and MRI

    - Allow precise visualization of the anatomic location of

    tumor and surrounding structures

    - Better patient selection for spesific treatment of limb

    salvage procedure

    JAm Acad Orthop Surg 2003;11:25-37.

    Consideration of Limb Salvage Procedure :

    1. An upper extremity tumor needs resection of the

    articular portion of the distal humerus or proximal ulna

    2. Disfunction of the elbow, wrist, and hand due to

    abundant of neurovascular structures in this location

    3. Psychological problem associated with tradition and

    aesthetic

    J Bone Joint Surg [Br] 1996;78-B:652-57 hal 26

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    Conclusion

    - The management of malignant bone tumors still presents many challenge

    - Advances in imaging, chemotherapy and reconstructive surgery can offered

    limb sparing surgery

    - Functional outcome and patient satisfaction appear to be at least as good,

    and probably better after reconstruction than after ablation