7/31/2019 Drugs Doses
8/9
MANAGEMENT OF THE CHILD WITH A SERIOUS INFECTION OR SEVERE
MALNUTRITION
142
A2.7 Bronchodilators/Anti-inflammatory agents for treatment of
wheeze
Drug by route of delivery Dosage Dosing intervals Products
Acute episode Maintenance
Aminophylline
Oral 6 mg/kg dose Every 6 hours Tablets: 100 mg or 200 mg
IV Initial dose: 56 mg/kg
Note: give IV (max. 300 mg) if the child has notaminophylline
slowly taken aminophylline or theophylline
over 2060 minutes within 24 hours
Maintenance dose: 5 mg/kg OR Every 6 hours or 250 mg/10 ml
ampoule
continuous infusion: 0.9 mg/kg/hour continuous infusion
Prednisolone a 1 mg/kg twice a day for 3 days
SalbutamolOral 211 months: 1 mg dose Every 68 hours Every 8
hours Syrup: 2 mg/5 ml
14 years: 2 mg dose Tablets: 2 and 4 mg
Metered dose inhalation 200g/2 doses Every 4 hoursb Every 68
hours 200 doses per inhaler
(aerosol with spacer)
Nebulized 2.5 mg/dose Every 4 hoursb Every 68 hours 5 mg/ml so
lut ion
2.5 mg in 2.5 ml single dose
units
Epinephrine (adrenaline) As a rapid-act ing bronchodilator if
salbutamol is not available: 0.01 ml/kg (up to a maximum of 0.3 ml)
of 1:1000 solution
given subcutaneously with a 1 ml syringe
a 1 mg prednisolone is equivalent to 5 mg hydrocortisone or 0.15
mg dexamethasone.b
In severe asthmatic attacks, it can be given up to 1 hourly.
A2.8 Analgesics
Analgesics Dose according to body weightDosage Form 3
