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Drawing Sta+s+cal Conclusions Dorota Glowacka [email protected]

Drawing(Stas+cal(Conclusions( · Today’s(Lecture(• Interpre+ng(stas+cal(results(–aprocess(linked(to(study(design.(• Randomized(experimentvs.(observaonal(data • Stas+cal(measure(of(uncertainty

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Drawing  Sta+s+cal  Conclusions  

Dorota  Glowacka  [email protected]  

Today’s  Lecture  

•  Interpre+ng  sta+s+cal  results  –  a  process  linked  to  study  design.  

•  Randomized  experiment  vs.  observa+onal  data  

•  Sta+s+cal  measure  of  uncertainty  •  Chance  mechanism  –  understanding  whether  a  chance  mechanism  was  used  and  for  what  purpose,  e.g.  sample  selec+on,  group  alloca+on,  etc.  

Mo+va+on  and  Crea+vity  Instruc(ons:  Please  rank  the  following  list  of  reasons  for  

     wri(ng,  in  order  of  personal  importance  to  you.    •  You  get  a  lot  pleasure  out  of  reading  something  good  that  you  have  wriKen.  

•  You  enjoy  the  opportunity  for  self  expression.  •  You  achieve  new  insights  through  your  wri+ng.  •  You  derive  sa+sfac+on  from  expressing  yourself  clearly  and  eloquently.  

•  You  feel  relaxed  when  wri+ng.  •  You  like  to  play  with  words.  •  You  enjoy  becoming  involved  with  ideas,  characters,  events,  and  images  in  your  wri+ng.  

Mo+va+on  and  Crea+vity  Instruc(ons:  Please  rank  the  following  list  of  reasons  for      

 wri(ng,  in  order  of  personal  importance  to  you.    •  You  realize  that,  with  the  introduc+on  of  dozens  of  magazines  

every  year,  the  market  for  free-­‐lance  wri+ng  in  constantly  expanding.    

•  You  want  you  wri+ng  teachers  to  be  favourably  impressed  with  your  wri+ng  talent.    

•  You  have  heard  of  cases  where  one  bestselling  novel  or  collec+on  of  poems  has  made  the  author  financially  secure.  

•  You  enjoy  public  recogni+on  of  your  work.  •  You  know  that  many  of  the  best  jobs  available  require  good  wri+ng  

skills.  •  You  that  wri+ng  ability  is  one  of  the  major  criteria  for  acceptance  

into  graduate  school.  •  Your  teachers  and  parents  have  encouraged  you  to  go  into  wri+ng.    

Intrinsic  group  

12.0   20.5  

12.0   20.6  

12.9   21.3  

13.6   21.6  

16.6   22.1  

17.2   22.2  

17.5   22.6  

18.2   23.1  

19.1   24.0  

19.3   24.3  

19.8   26.7  

20.3   29.7  

Extrinsic  group  

5.0   17.4  

5.4   17.5  

6.1   18.5  

10.9   18.7  

11.8   18.7  

12.0   19.2  

12.3   19.5  

14.8   20.7  

15.0   21.2  

16.8   22.1  

17.2   24.0  

17.2  

           Sample  size:    24              23                Average:    19.88            15.74  

Standard  devia(on:    4.44            5.25  

Star1ng  salaries  for  32  male  and  61  female  clerical  hires  at  a  bank  

Males   Females  4,620   5,700   6,000   3,900   4,500   4,800  

 5,220   5,400  

 5,640  

5,040   6,000   6,000   4,020   4,620   4,800    

5,220   5,400    

5,700  

5,100   6,000   6,000   4,290   4,800   4,980   5,280   5,400    

5,700    

5,100   6,000   6,300   4,380   4,800    

5,100   5,280   5,400    

5,700    

5,220   6,000   6,600   4,380    

4,800    

5,100    

5,280   5,400    

5,700    

5,400   6,000   6,600   4,380    

4,800    

5,100    

5,400   5,400    

5,700    

5,400   6,000   6,600   4,380    

4,800    

5,100    

5,400    

5,400    

6,000  

5,400   6,000   6,840   4,380    

4,800    

5,100    

5,400    

5,520   6,000  

5,400   6,000   6,900   4,440   4,800    

5,100    

5,400    

5,520   6,120  

5,400   6,000   6,900   4,500   4,800    

5,160   5,400    

5,580   6,300  

6,000   8,100   6,300  

Sex  discrimina+on  in  employment  

Randomized  experiment  vs.  observa+onal  study  

Crea(vity   study   –   randomized   experiment   and   so  we  infer  that  difference  in  crea+vity  was  caused  by  difference   in   mo+va+onal   ques+onnaire.   Because  subjects   were   not   selected   randomly   from   any  popula+on,   extending   this   inference   to   any   other  group  is  specula+ve.  Sex   discrimina(on   in   employment   –   observa(onal  study   so   although   there   is   evidence   that   males  received   larger   salaries   than   females,   the   data  cannot  address  whether  the  difference  is  due  to  sex  discrimina+on.    

Causal  Inference  

•  Randomized   experiment   –   inves+gator  controls   assignment   of   experimental   units   to  groups  and  uses  a  chance  mechanism  to  make  assignments.  

•  Observa(onal  study  –  group  status  of  subjects  established  beyond  control  of  inves+gator.  Sta(s(cal  inferences  of  cause  and  effect  

rela(onships  can  be  drawn  from  randomized  experiments  but  not  from  observa(onal  studies.  

Do  we  need  observa+onal  studies?  

•  Establishing  causa(on   is  not  always   the  goal,  e.g.   sickle-­‐cell   anaemia   is   more   common  among  African  and  Mediterranean  popula+on  than  in  North-­‐European  popula+on.  

•  Analysis   of   observa(onal   data   may   lend  evidence   toward   causal   theories   and   suggest  the   direc(on   of   future   research,   e.g.   further  studies   to   establish   the   cause   of   sickle-­‐cell  anaemia.  

Inference  to  popula+ons  

•  Inference   to   popula+ons   can   be   drawn   from  random  sampling  studies.  

•  Random   sampl ing   ensures   that   a l l  subpopula+ons  are  represented  in  the  sample  in   roughly   the   same   mix   as   in   the   overall  popula+on.  

•  A   typical   method   for   choosing   a   random  sample  is  by  loFery.    

Inference  and  Chance  Mechanisms  

Uncertainty  in  Randomized  Experiments  

Null  Hypothesis  

The   null   hypothesis   is   the   commonly   accepted  fact.   Researchers   work   to   reject   the   null  hypothesis   with   an   alterna(ve   hypothesis.   The  null   hypothesis   specifies   a   simpler   state   of  affairs.  

Crea+vity  study  null  hypothesis:  The  ques(onnaire  has  no  effect.  

 

p-­‐value  

In  randomized  experiment  the  p-­‐value  is  the  probability  that  randomiza+on  alone  leads  to  a  test  sta+s+c  as  extreme  or  more  extreme  than  the  one  observed.  The  smaller  the  p-­‐value,  the  more  unlikely  it  is  that  the  chance  assignment  is  responsible  for  discrepancy  between  groups,  and  the  greater  the  evidence  that  the  null  hypothesis  is  incorrect.    

p-­‐value  

•  In  crea+vity  study:  4  of  1000  regroupings  produced  differences  larger  than  the  observed  difference  -­‐-­‐>  p-­‐value  =  4/1000  =  0.004  (one-­‐sided  p-­‐value)    

•  Two-­‐sided  p-­‐value  –  consider  values  smaller  than  -­‐4.14  

Two-­‐sided  p-­‐value  =  11/1000  =  0.011  

Compu+ng  p-­‐values  

•  Enumera+on  of  all  possible  regroupings  of  the  data.  

•  Simula+ng  a  large  number  of  randomiza+ons  and  finding  propor+on  of  these  that  produce  a  test  sta+s+c  at  least  as  extreme  as  the  observed  one.  

•  Approximate  the  randomiza+on  distribu+on  with  a  mathema+cal  curve.  

Uncertainty  in  observa+onal  studies  

Permuta+on  distribu+on    

•  Hypothesis:  employer  assigned  star+ng  salaries  to  the  employees  at  random.  

•  Permuta(on  distribu(on:  collec+on  of  differences  in  averages  from  all  possible  assignments  of  star+ng  salaries  to  individuals  (p-­‐value  <  0.00001)  

•  Conclusion:  employer  did  not  assigned  star+ng  salaries  at  random.