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© AZTI. Todos los derechos reservados © AZTI. Todos los derechos reservados Dr Matxalen Uriarte [email protected] From Good Food to precision Nutrition Food & Health Department

Dr Matxalen Uriarte [email protected] Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

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Page 1: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados© AZTI. Todos los derechos reservados

Dr Matxalen [email protected]

From Good Foodto precision Nutrition

Food & Health Department

Page 3: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Experts in Food innovation

FOOD & HEALTH

/ Precision nutrition (cellmembrane lipidomics)

/ BIG DATA for new consumer segmentation

/ Personalized food

NEW FOODS

/ New products

/ Food processing technologies

/ Pleasure, convenience and sustainability

FOOD QUALITY, SAFETY AND IDENTITY

/ Food Safety

/ Food control

/ Food identity

/ Analytical services

EFFICIENT AND SUSTAINABLE PROCESSES

/ Production efficiency and savings

/ Food chain 4.0

/ Ergonomic improvements

/ Circular economy: Valorisation of food by-products

/ Environmental assessment and communication

CONSUMER AND MARKET

/ Trend Identification and application

/ Market Research with Consumers

/ Competitive surveillance

Page 4: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

¿What is Good Food?

Traditional meals...Village food…Organic food...

Page 5: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

New disorders due to unhealthy

life style …Non transmisible diseases

(70% of deaths globally)

global dataSpain

Cardiovascular diseases

Cancer

Respiratory diseases

Other non transmisible diseases

Transmisible diseases and impaired

conditions

Injuries

Page 6: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

New pathologies due to malnutrition

One fifth of the world population will be

obese by 2025

Chronicity and pluripathology ….Chronic patients ≥ 65 years old. Prevision 2049

Annual increase 2011-2040: 2%

Perception of health - 75.1% of men report having a good health status, compared to 67% of women. Logically, positive perception decreases with age.

Chronic diseases - Hypertension, lumbago and cholesterol, the most frequent.The most common problems are also those associated with aging and overweight

Obesity and overweight - Overcome the psychological barrier of 50%. More than 52.7% of the adult population is above the weight considered normal.Obesity increases with the age of the population.The extra weight are a serious health problem that has a direct relationship with diseases as serious as cardiovascular, cancer or diabetes.

Spain…

(INE, data from 2014)

Page 7: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Food is…

Page 8: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

¿What is healthy FOOD?

Spanish Food Pyramid

SENC (Spanish Society of Community Nutrition)

Do we know what quantities we should eat?Do we know the type of nutrients / ingredients

which are part of the food?How do they impact on us?Is the traditional food the only good food?Everything natural is good?

Page 9: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Mediterranean diet pyramid: modern life style

Good nutrition is a healthy diet that consists of eating a variety of foods that provide you with the nutrients you need to stay healthy, feel good and have energy.

Nutrients: proteins, carbohydrates, fats, water, vitamins and minerals.

Balanced and varied diet + regular exercise

¿What is healthy FOOD?

Page 10: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Switzerland

Australia

Variety

Moderation

Balance

¿What is healthy FOOD?

Page 11: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

A reference

tool, easy

to

interpret

¿What is healthy FOOD?

Page 12: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

¿which are the basis of the

nutritional Pyramid?

• Study of 7 countries (1958-1964): Mediterranean diet.

• The European Prospective Study on Diet, Cancer and Health (EPIC) (1992)

• DASH (1994-1996): Dietary approaches to stop hypertension.

• PREDIMED (2003-2011): Prevention with Mediterranean Diet.

• Predimed-Plus (2016): primary cardiovascular prevention

Nutritional epidemiologyPROYECTO Breve descripción

[email protected] - Estudio de la

prevalencia de la Diabetes en

España (ES)

El estudio [email protected] responde a la necesidad de actualizar los datos referentes a la prevalencia

de DM2 en España y otros factores de riesgo cardio-metabólicos. De este modo se ha

desarrollado un gran estudio nacional de epidemiología de la diabetes mellitus y de los factores

de riesgo cardiovascular asociados, como obesidad o hipertensión arterial, entre otros, así como

sobre hábitos de salud.

Estudio de investigación clínica impulsado por CIBERDEM que busca poner a prueba la hipótesis

de que una dieta rica en sardina mejora el control metabólico en pacientes con diabetes mellitus

tipo 2.

Objetivos: Evaluar los efectos de una dieta rica en sardina en el control glucémico, marcadores

de inflamación, presión arterial, metabolismo lipídico y microbiota intestinal de pacientes con

diabetes tipo 2 de diagnóstico reciente o sin tratamiento farmacológico.

ENRICA - Estudio de Nutrición y

Riesgo Cardiovascular en España

(ES)

Informa sobre la frecuencia y distribución de los principales componentes de la historia natural

de la enfermedad cardiovascular (ECV). Por tanto, se describen factores de riesgo cardiovascular

ligados a los estilos de vida, como el consumo de tabaco, la actividad física y la alimentación.

También se proporciona información sobre factores biológicos de riesgo cardiovascular, como el

exceso de peso, el síndrome metabólico, la hipertensión arterial, la dislipemia o la diabetes

mellitus.

Proyecto PILCHARDUS (ES)

Page 13: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

PROYECTO Breve descripción

Is a prospective cohort with more than 521 000 study participants enrolled from 23 centres in 10

western European countries. Detailed information on diet, lifestyle characteristics,

anthropometric measurements, and medical history was collected at recruitment (1992—1999). Working groups: Cancer Working Groups, Cardiovascular disease (EPIC-Heart), Diabetes

(InterAct), Obesity/PANACEA, Biostatistics, Nutrition, Healthy ageing (EPIC-Elderly),

Osteoporosis and fractures, Acrylamide, Reproducibility of biomarkers, Mortality,

Neurodegeneration

MEDIGENE (EU)Characterization of the genetic landscape of Southern Europe, Balkans, Anatolia and North

Africa; Study of the variability of 150 candidate genes in both natives and immigrant populations;

Search for potential new genes and gene - environment interaction for metabolic syndrome

PREDIMED - Prevención con Dieta

Mediterránea (ES)

Impacto de la dieta mediterránea en la prevención de enfermedades cardiovasculares. La

importancia de los aceites .

El ensayo PREDIMED (PREvención con DIeta MEDiterránea) es el estudio de mayor envergadura

que se ha realizado sobre nutrición en España. Se valoraron los efectos de la Dieta Mediterránea

en la prevención primaria de la enfermedades crónicas. En este estudio colaboraron más de 90

investigadores de los principales grupos de nutrición españoles.

Se demostró la eficacia de la Dieta Mediterránea en la prevención de la enfermedad

cardiovascular en una población de alto riesgo cardiovascular ( con diabetes mellitus ó tres o más

factores de riesgo).

En la actualidad se trabaja en el estudio PREDIMED PLUS cuya hipótesis de trabajo es que una

dieta mediterránea hipocalórica junto con un aumento de la actividad física reducirá la

incidencia de enfermedad cardiovascular en sujetos con síndrome metabólico con

sobrepeso/obesidad.

EPIC::The European Prospective

Investigation into Cancer and

Nutrition (EU) Observational, prospective

cohort studies

Nutritional epidemiology in adults, few studies at infant stages

Are there nutritional intervention projects?

¿which are the basis of the

nutritional Pyramid?

Page 14: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Biotecnology…

Page 15: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Clinical and molecular data…

clínicos…

Page 16: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

AZTI bet

Probably the best cause-effect analysis regarding food

CELL MEMBRANE LIPIDOMICS

Healthy Food Regeneration of cell

membrane lipid profile

Precision Nutrition

HEALTH BALANCE

OPTIMAL PERFORMANCE

PREVENTION

Page 17: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Cell membrane lipidomics

Page 18: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Presicion and Personalization

Page 19: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

It is not just a matter of information

and knowledgeWe are irrational when choosing food…

If healthy food is not nice we don’t adhere to it…

How do we feed ourselves??

Is it easy to have a healthy diet daily?

Page 20: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Watch out!

Page 21: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Evolution

An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity. Simopoulos, Nutrients 2016.

Fatty acids equilibrium

Quality of Life

archaic diet

modern diet

Page 22: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

It is not just a matter of information

and knowledge

We need diet Education…

We need healthy food accesibility in

the market...

We need more food services to adhere

to a nice and healthy food…

We need Gastronomy…

Page 23: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

It is not only important

diet should be balanced

and varied.

There are other aspects that must be taken into account…

A definition of healthy diet is needed

What is conditioning people to adhere

to healthy habits?

Multidisciplinary interactions and

action plans

We need ORCHESTRATION of all actors

It is not just a matter of information

and knowledge

Page 24: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

What is healthy diet?

Initiatives for a healthy diet in the Basque Country – Basque Government

1. Product2. Combination & proportion3. Forms of consumption

Page 25: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Nutritional and safety

properties

Accesibility

• Functional

• Economical

• Sensory

• Emotional

1. Product

What is healthy diet?Initiatives for a healthy diet in the Basque Country – Basque Government

Page 26: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

What is healthy diet?

Initiatives for a healthy diet in the Basque Country – Basque Government

2. Combination & proportion

Nutritional equilibrium

Adapted to personal needs

• considering clinical singularities

• Life styles

• Aesthetics

Page 27: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

What is healthy diet?Initiatives for a healthy diet in the Basque Country – Basque Government

3. Forms of consumption

Elaboration and consumption

• Gastronomy tradition

• Pleasure

• Culture

• portions

Moments of consumption

• Life style

• shared habits…

Page 28: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

What conditions healthy eating?

Limited purchasing capacity

Economical interests of big

companies

Diet and pleasure

New consumption trends

Tradition

Gastronomy

Energy poverty

Training of people

Life rhythm

High cost of transformation

of production processes

Low development of Agro-

Food industry

etc…

1. Product2. Combination & proportion3. Forms of consumption

Page 29: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Building a healthy ecosytem

18 healthy

initiatives promoted by the Basque Government

1. Assets map2. Information sources3. 360° update of school canteens4. Intelligent and healthy VENDING5. Multimedia guide for restaurants and bars6. ….7. …8. Healthy educational ecosystem9. App “healthy eating LEAGUE for young people”10. …11. Healthy eating at work places12. Creating trends: mediatic impulse for healthy eating13. …etc

Page 30: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Data of molecular profiles,Data of ingredients, food, products ...Data of industrial processes, technologies impact onnutrients ...Consumer preferences data ...

Food Smart Cities for Development projecthttp://www.milanurbanfoodpolicypact.org/project/

EU platform for action on diet, physical activity and health https://ec.europa.eu/health/nutrition_physical_activity/platform_en

Healthy ecosystemTO WORK IN…

Regio Food Valleyhttps://www.regiofoodvalley.nl/

Page 31: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Empowerment of the

citizen/consumerEmpowerment of the

patient

Prevention and

promotion of Healthphilosophy

Contributes to the sustainability of the Health System

Informationand

Education

Informationand

Education

Health and Pleasure

The challenge: healthy and

sustainable growing

Access to

personalized

and precision

medicine

Access to

healthy and

personalized

food products

Page 32: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Big data, data mining and I.A.

Page 33: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Is food sector ready?

Functional food

Page 34: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Perfil A

joven

© AZTI. Todos los derechos reservados

Page 35: Dr Matxalen Uriarte muriarte@azti.es Food & Health ......FOOD QUALITY, SAFETY AND IDENTITY / Food Safety / Food control / Food identity / Analytical services EFFICIENT AND SUSTAINABLE

© AZTI. Todos los derechos reservados

Índice

Txatxarramendi ugarte z/g48395 Sukarrieta, Bizkaia

Herrera Kaia. Portualdea z/g20110 Pasaia, Gipuzkoa

Astondo Bidea, Edificio 609Parque Tecnológico de Bizkaia48160 Derio, Bizkaia

THANK YOU!