1
ABSTRACTS Heart, Lung and Circulation Abstracts S119 2008;17S:S1–S209 sine. No patients suffered persistent adverse effects from adenosine. Conclusion: Adenosine facilitated non-selective venogra- phy of the right atrium shows promise as a technique to facilitate visualisation of the CS. doi:10.1016/j.hlc.2008.05.284 284 Does Radio-opaque Contrast Use During Biventricular Pacemaker Implantation (BiVI) Adversely Affect Renal Function? Hany Abed , Neva Bull, Robert Blake, Malcom Barlow, James Leitch, Stuart Turner The John Hunter Hospital, Newcastle, NSW, Australia Results and discussion: Thirty patients were studied (21 male, 66 ± 13 years old, QRS duration; 166 ± 30 ms, LV end-diastolic diameter; 68 ± 10mm, LV ejection fraction; 26 ± 10% and NYHA; 3.4 ± 0.4). 73% had impaired renal function before BiVI. A mean volume of 160 ± 49 ml non- ionic iso-osmolar contrast was used during implantation. Creatinine (Cr) increased in four patients but only one patient met the criteria for CIN. Mean Cr, for the entire group, decreased from 140 ± 9 mol/L to 115 ± 8 mol/L (Cr 18% [95% C.I.: 12, 36%, p < 0.001]) such that only 49% had renal impairment post-BiVI. These findings sug- gest the improvement in cardiac function, and hence renal perfusion, as a result of BiVI outweighs any adverse con- trast effects. Conclusion: Contrast load during BiV implantation is rarely associated with contrast-induced nephropathy. In the majority of patients, BiVI results in a net improvement in renal function. doi:10.1016/j.hlc.2008.05.285 285 Effect of Electrical Cardioversion on Atrial Fibrillation Resistant to Termination Christopher X. Wong , Anthony G. Brooks, Martin K. Stiles, Bobby John, Dennis H. Lau, Hany Dimitri, Ross L. Roberts-Thomson, Pawel Kuklik, Scott R. Willoughby, Lor- raine Mackenzie, Glenn D. Young, Prashanthan Sanders Cardiovascular Research Centre, Department of Cardiology, Royal Adelaide Hospital and the Disciplines of Medicine and Physiology, University of Adelaide, Adelaide, Australia Introduction: Electrical cardioversion of atrial fibrillation (AF) is commonly unsuccessful and often requires mul- tiple attempts before eventual termination. We sought to determine the characteristics of AF resistant to cardiover- sion and the effect of cardioversion on the fibrillatory process. Methods: Cardioversion was performed following AF ablation in 106 patients (96 M, 55 ± 12 years). AF cycle length (CL) and dominant frequency (DF) were measured within the coronary sinus at baseline prior to ablation, and immediately before and after unsuccessful cardioversion. Results: There were a total of 40 unsuccessful cardiover- sions. Cardioversion caused a significant increase in CL, and fibrillatory activity was observed to markedly slow immediately following cardioversion, before accelerating to a plateau slower than that that prior to cardiover- sion (205 ± 32 to 217 ± 41 ms, p <0.001). Ten patients had multiple unsuccessful cardioversions during the same procedure, the maximum being 5. Of these, those resistant to a greater number of cardioversions before termination had shorter baseline CL (p < 0.001). Subsequent unsuc- cessful cardioversion attempts showed greater baseline to postcardioversion increase in CL (47 ± 79 vs. 58 ± 78 vs.

Does Radio-opaque Contrast Use During Biventricular Pacemaker Implantation (BiVI) Adversely Affect Renal Function?

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Page 1: Does Radio-opaque Contrast Use During Biventricular Pacemaker Implantation (BiVI) Adversely Affect Renal Function?

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Heart, Lung and Circulation Abstracts S1192008;17S:S1–S209

sine. No patients suffered persistent adverse effects fromadenosine.Conclusion: Adenosine facilitated non-selective venogra-phy of the right atrium shows promise as a technique tofacilitate visualisation of the CS.

doi:10.1016/j.hlc.2008.05.284

284Does Radio-opaque Contrast Use During BiventricularPacemaker Implantation (BiVI) Adversely Affect RenalFunction?

Hany Abed ∗, Neva Bull, Robert Blake, Malcom Barlow,James Leitch, Stuart Turner

The John Hunter Hospital, Newcastle, NSW, Australia

Results and discussion: Thirty patients were studied (21me2fiCpg(4gptCrti

doi:10.1016/j.hlc.2008.05.285

285Effect of Electrical Cardioversion on Atrial FibrillationResistant to Termination

CSRr

RP

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ale, 66 ± 13 years old, QRS duration; 166 ± 30 ms, LVnd-diastolic diameter; 68 ± 10 mm, LV ejection fraction;6 ± 10% and NYHA; 3.4 ± 0.4). 73% had impaired renalunction before BiVI. A mean volume of 160 ± 49 ml non-onic iso-osmolar contrast was used during implantation.reatinine (Cr) increased in four patients but only oneatient met the criteria for CIN. Mean Cr, for the entireroup, decreased from 140 ± 9 �mol/L to 115 ± 8 �mol/L�Cr −18% [95% C.I.: −12, −36%, p < 0.001]) such that only9% had renal impairment post-BiVI. These findings sug-est the improvement in cardiac function, and hence renalerfusion, as a result of BiVI outweighs any adverse con-

rast effects.onclusion: Contrast load during BiV implantation is

arely associated with contrast-induced nephropathy. Inhe majority of patients, BiVI results in a net improvementn renal function.

hristopher X. Wong ∗, Anthony G. Brooks, Martin K.tiles, Bobby John, Dennis H. Lau, Hany Dimitri, Ross L.oberts-Thomson, Pawel Kuklik, Scott R. Willoughby, Lor-

aine Mackenzie, Glenn D. Young, Prashanthan Sanders

Cardiovascular Research Centre, Department of Cardiology,oyal Adelaide Hospital and the Disciplines of Medicine andhysiology, University of Adelaide, Adelaide, Australia

ntroduction: Electrical cardioversion of atrial fibrillationAF) is commonly unsuccessful and often requires mul-iple attempts before eventual termination. We sought toetermine the characteristics of AF resistant to cardiover-ion and the effect of cardioversion on the fibrillatoryrocess.ethods: Cardioversion was performed following AF

blation in 106 patients (96 M, 55 ± 12 years). AF cycleength (CL) and dominant frequency (DF) were measured

ithin the coronary sinus at baseline prior to ablation, andmmediately before and after unsuccessful cardioversion.esults: There were a total of 40 unsuccessful cardiover-

ions. Cardioversion caused a significant increase in CL,nd fibrillatory activity was observed to markedly slowmmediately following cardioversion, before acceleratingo a plateau slower than that that prior to cardiover-ion (205 ± 32 to 217 ± 41 ms, p < 0.001). Ten patients hadultiple unsuccessful cardioversions during the same

rocedure, the maximum being 5. Of these, those resistanto a greater number of cardioversions before terminationad shorter baseline CL (p < 0.001). Subsequent unsuc-essful cardioversion attempts showed greater baseline toostcardioversion increase in CL (47 ± 79 vs. 58 ± 78 vs.