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Do NowDo Now1. Identify the organelle that stores our genetic
information
2. Yesterday we learned that the BRCA1 protein helps prevent cells from becoming cancerous. What is the effect of having a mutation like Theresa’s in the BRCA1 gene?
How is our genetic information stored?
Levels of Genetic Organization
Largest
Smallest
Nucleus Organelle that contains the DNA
How is our genetic information stored?Levels of Genetic Organization
Largest
Smallest
Nucleus Organelle that contains the DNA
Chromosome Large coiled bundles of DNA
How is our genetic information stored?Levels of Genetic Organization
Largest
Smallest
Nucleus Organelle that contains the DNA
Chromosome Large coiled bundles of DNA
Gene section of DNA that codes for a certain protein and leads to a certain trait
How is our genetic information stored?Levels of Genetic Organization
Largest
Smallest
Nucleus Organelle that contains the DNA
Chromosome Large coiled bundles of DNA
Gene section of DNA that codes for a certain protein and leads to a certain trait
Nucleotide/ Base
The building blocks of DNA (A, T, C, & G)
How is our genetic information stored?
C--
T--
G--
T--
A--
Base Pair RuleA + T
(Adenine + Thymine)C + G
(Cytosine + Guanine)
Is it a Chromosome, Gene, Is it a Chromosome, Gene, or Nucleotide?or Nucleotide?
Circle one and explain how you know.
Yesterday we learned about a segment of nucleotides that serves as instructions about how to make the BRCA protein. This can be called a… chromosome gene nucleotide
How do you know?
A scientist used an electron microscope and a laser to slice a nucleus in half and observe its contents. He saw 23 bundled structures inside. These can be called… chromosomes genes nucleotides
How do you know?
These lines point to… chromosomes
genes nucleotides
How do you know?
A-T-C-C-G-AA-T-C-C-G-A
DNA Sequence
determines
Protein Made
determines
Trait
Why do we look the way we do?
A-T-C-C-G-AA-T-C-C-G-A
DNA Sequence
determines
Protein Made
determines
Trait
Why do we look the way we do?
So does everyone have the same So does everyone have the same sequencesequence of DNA? of DNA?
Crazy Fact: Crazy Fact: Each one of your cells Each one of your cells has the EXACT same sequence of has the EXACT same sequence of DNADNA
Nerve Cell Stomach Cell
How is it possible?!How is it possible?! Genes that are needed in a cell Genes that are needed in a cell are are activatedactivated (turned on) and (turned on) and genes that are not needed are genes that are not needed are deactivated deactivated (turned off).(turned off).
Nerve Cell Stomach Cell
Stop and JotDNA is made up 4 building blocks- A, T, C, G. Is the
sequence (order) of these nucleotides the same in your cells as they are in the person sitting next to you? Why or Why not?
Is the sequence of nucleotides the same in your eye cell as it is in your liver cell? Explain why or why not.
Partner Practice1. Which statement describes one
characteristic of this molecule?(1) It is the template for the replication of
genetic information.(2) Organic catalysts are made up of these
molecules.(3) It is different in each cell of an organism. (4) Cell membranes contain many of these
molecules.
Partner Practice2. Which diagram represents the relative sizes of the
structures listed below?
Partner PracticeA human liver cell is very different in structure and
function from a nerve cell in the same person. This is best explained by the fact that
(1)different genes function in each type of cell (2) different DNA is present in each type of cell(3) liver cells contain fewer chromosomes than
nerve cells (4) different DNA is present in each type of cell