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DISCUSSION PAPER SERIES IZA DP No. 11470 Rania Gihleb Osea Giuntella Ning Zhang The Effects of Mandatory Prescription Drug Monitoring Programs on Foster Care Admissions APRIL 2018

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  • DISCUSSION PAPER SERIES

    IZA DP No. 11470

    Rania GihlebOsea GiuntellaNing Zhang

    The Effects of Mandatory Prescription Drug Monitoring Programs on Foster Care Admissions

    APRIL 2018

  • Any opinions expressed in this paper are those of the author(s) and not those of IZA. Research published in this series may include views on policy, but IZA takes no institutional policy positions. The IZA research network is committed to the IZA Guiding Principles of Research Integrity.The IZA Institute of Labor Economics is an independent economic research institute that conducts research in labor economics and offers evidence-based policy advice on labor market issues. Supported by the Deutsche Post Foundation, IZA runs the world’s largest network of economists, whose research aims to provide answers to the global labor market challenges of our time. Our key objective is to build bridges between academic research, policymakers and society.IZA Discussion Papers often represent preliminary work and are circulated to encourage discussion. Citation of such a paper should account for its provisional character. A revised version may be available directly from the author.

    Schaumburg-Lippe-Straße 5–953113 Bonn, Germany

    Phone: +49-228-3894-0Email: [email protected] www.iza.org

    IZA – Institute of Labor Economics

    DISCUSSION PAPER SERIES

    IZA DP No. 11470

    The Effects of Mandatory Prescription Drug Monitoring Programs on Foster Care Admissions

    APRIL 2018

    Rania GihlebUniversity of Pittsburgh and IZA

    Osea GiuntellaUniversity of Pittsburgh and IZA

    Ning ZhangUniversity of Pittsburgh

  • ABSTRACT

    IZA DP No. 11470 APRIL 2018

    The Effects of Mandatory Prescription Drug Monitoring Programs on Foster Care Admissions*

    The opioid epidemic is a national public health emergency. As the number of fa- tal

    overdoses and drug abuse skyrockets, children of opioid-dependent parents are at increased

    risk of being neglected, abused or orphaned. While some studies have examined the effects

    of policies introduced by states to restrict prescription drug supply on drug abuse, there is

    no study analyzing their effects on children. This paper estimates the effect of must-access

    prescription drug monitoring programs (PDMPs) on child removals. To identify the effects of

    the programs on foster care caseloads, we exploit the variation across states in the timing

    of adoption of must-access PDMPs using an event-study approach as well as standard

    difference-in-difference models. Consistent with previous evidence examining the effects of

    PDMPs on drug abuse, we find that operational PDMP did not have any significant effects

    on foster care caseloads. However, the introduction of mandatory provisions reduced child

    removals by 10%. Exploring the reasons of removals, we show that these effects are driven

    by the reductions in cases of child neglect. There is also evidence of significant reductions

    in removal cases associated with child physical abuse.

    JEL Classification: I12, I18, J13

    Keywords: opioid epidemic

    Corresponding author:Rania GihlebDepartment of EconomicsUniversity of Pittsburgh4901 Wesley W. Posvar Hall230 South Bouquet StreetPittsburgh, PA 15260USA

    E-mail: [email protected]

    * We are grateful to all the seminar attendees at the University of Pittsburgh. We benefitted from comments from

    Janet Currie, Mark Borgshulte, Jason Cook, and Betsey Stevenson. We are thankful to the National Data Archive on

    Child Abuse and Neglect for providing the data on foster care caseloads and child maltreatment.

  • 1 Introduction

    The United States are in the midst of an opioid overdose epidemic. Drug mortality rose

    by 300% between 1999 and 2016. In 2016, the US experienced the largest annual increase

    in drug overdose deaths ever recorded. This rapid increase in drug mortality is related to

    the diffusion of prescription opioids (e.g., Oxycontin) and more recently to the spread of

    fentanyl, an opioid typically used as a pain medication (Paulozzi et al., 2014; Dart et al.,

    2015; Ruhm, 2018). Public health officials consider the current opioid epidemic crisis the

    worst drug crisis in America history.

    As recently highlighted by Quast et al. (2018), a critical aspect of this drug crisis are its

    effects on the ability of addicted parents to care for their children. In 2015, there were 683,000

    victims of child abuse and neglect reported to child protective services (CPS). According to

    the US Department of Health and Human Services (2015), 25.4% of victims of child abuse

    were reported with the drug abuse caregiver risk factor and the evidence suggests there

    is an increase in caregiver drug abuse. Parental neglect and parental drug abuse are the

    two most common reasons for removals (AFCARS Report, 2015). The opioid epidemic has

    forced thousands of children from their homes, at risk of being neglected, abandoned, or

    orphaned by drug-addicted parents. There is increasing concern that America’s opioid crisis

    may overwhelm the US foster case system as thousands of children are taken out of the care

    of addicted parents.1 Foster care numbers have been soaring in many US states. In 2015,

    429,000 children were in foster care with a 6.7% increase with respect to 2013. This surge

    is in large part due to the increase in the number of cases related to parental drug-abuse.

    Figure 1 illustrates how the trend in drug-related child abuses and the number of children in

    foster because of drug-related abuses closely mirrored the increase in fatal overdoses. From

    2000 to 2015 number of drug-related foster care caseloads have increased by 66% (Figure

    2). These increases in the foster care population generate significant monetary and non-

    1See https://www.npr.org/2017/12/23/573021632/the-foster-care-system-is-flooded-with-children-of-the-opioid-epidemic

    2

  • monetary costs. Previous research estimate that the fiscal costs of a child in foster care is

    approximately $20,000 (Zill, 2011) and documents that foster care placement can have large

    detrimental effects on children long-term outcomes (Doyle Jr, 2007, 2008). Of course this is

    only a part of the costs as child abuse and neglect have long-run effects on human capital,

    health outcomes and have been shown to increase the likelihood of engaging in crime and of

    substance abuse (Currie and Spatz Widom, 2010; Dube et al., 2003).

    To address the surge in prescription drug abuse, states have adopted prescription drug

    monitoring programs (PDMP). These programs track prescriptions helping in identifying

    doctor shopping and prescription drug abuse. Currently, most states have adopted an op-

    erational PDMP, but only a few states mandated their use. The main contribution of this

    study is to evaluate the effects of prescription drug monitoring programs on child removals.

    To the best of our knowledge, this is the first study analyzing the effects of prescription drug

    monitoring programs on foster care admissions.

    Despite the growing attention raised by the press reports of state foster systems being

    overwhelmed by children of opioid-dependents, there is little empirical evidence documenting

    the relationship between opioid abuse and child removals. Cunningham and Finlay (2013)

    analyzed the effect of meth use on foster care admissions using an instrumental variable

    strategy. Their strategy relies on deviations in the real price of meth from national trends

    caused by large federal supply interdictions that affected meth supply. They find evidence

    of a positive elasticity of foster care with respect to meth use. However, a limitation of their

    empirical strategy is that it only exploits national variation in meth prices and thus cannot

    control for unobserved time-varying factors that may have caused changes in foster care

    caseloads. Using data from Florida counties for the period 2012-2015, Quast et al. (2018)

    document that an increase in opioid prescription rate was associated in an increase in the

    removal rate for parental neglect, with the effects largely driven by counties with the highest

    concentration of whites. Their analysis provides insightful findings, however it is limited

    by the short sample period, the local nature of the data which may not be representative

    3

  • of the US population and the small sample size which restricts their ability to control for

    county-level time-varying confounding factors.

    To identify the effects of PDMPs on foster care admissions we exploit variation in the

    timing of adoption of operational and mandatory PDMPs across US States using an event-

    study as well as standard difference-in-difference regression models. Consistent with previous

    studies analyzing the effects of PDMPs on drug abuse (Buchmueller and Carey, 2017; Dave

    et al., 2017), we find no evidence that operational PDMPs had significant effects on foster

    care admissions, while mandatory-access PDMPs reduced child removals by 10%. Our results

    suggest that mandatory PDMPs may reduce foster care costs by 476 million per year. Given

    the long-lasting implications of child maltreatment and neglect, our results suggest that

    programs aimed at controlling the supply of prescription drugs may have large long-run

    returns if effectively enforced.

    The paper is organized as follows. Section 2 discusses the background and presents the

    main data sources. We discuss the empirical specification in Section 3. Results are presented

    in Section 4. Section 5 concludes.

    2 Background and Data

    2.1 Prescription Drug Epidemic and Policy Response

    According to CDC estimates (Rudd, 2016), the rise in prescription drug use and abuse

    largely accounts for the trends in drug-related deaths. While the reasons behind the opioid

    epidemic are multiple have also been linkeds to long-run socio-economic decline (Case and

    Deaton, 2015), a growing set of studies relates the opioid epidemic to physician behavior

    and supply-side regulation (Alpert et al., 2017; Pacula et al., 2015; Ruhm, 2018). Among

    other factors, the market entry of OxyContin in 1996 and the diffusion of aggressive pain

    management contributed substantially to the surge in opioid use over he last two decades

    (Laxmaiah Manchikanti et al., 2012). Reports also suggest that most of the individuals at

    4

  • high risk of fatal overdose obtained prescription drugs from physicians and doctor shopping

    is considered the main source of supply.

    To respond to the dramatic increase in fatal overdoses and drug-abuse, states have intro-

    duced several programs to improve opioid prescribing, inform clinical practice and protect

    patients at risk. Prescription drug monitoring programs (PDMPs) are electronic databases

    that track controlled substance prescriptions in a state. PDMPs allow health authorities and

    pharmacies to have timely information about prescribing and patient behaviors and can help

    identifying patients who are receiving multiple prescriptions and may contribute to the epi-

    demic. Some states made the use of the database mandatory for physicians. Non-mandated

    PDMPs do not legally require health professionals to query them. However, since 2007 a

    few states have know extended their PDMP with mandatory access provisions which require

    doctors and pharmacies to query PDMP before prescribing a controlled substance.

    Previous studies evaluating the effects of PDMPs on opioid consumption reached different

    conclusions. There is consensus that PDMPs reduced oxycodone shipments (Kilby, 2015;

    Mallatt, 2017). The evidence is mixed when focusing on hydrocodone shipments or other

    abuse outcomes. While some studies found evidence that non-mandated PDMPs decreased

    fatal non-oxycodone related overdoses and poisonings (Mallatt, 2017; Patrick et al., 2016;

    Simoni-Wastila and Qian, 2012), most of them found evidence of small or null effects drug

    abuse (Simoni-Wastila and Qian, 2012; Meara et al., 2016). On the contrary, recent papers

    focusing on the effects of PDMP mandates found significant effects on opioid quantity and

    shopping behavior, abuse outcomes, substance abuse facility admissions, crime rates, and

    fatal drug overdoses (Buchmueller and Carey, 2017; Patrick et al., 2016; Dave et al., 2017;

    Borgschulte et al., forth.; Mallatt, 2017).

    To the best of our knowledge there is no study analyzing the effects of PDMP programs

    on foster care caseloads. In our analysis, we distinguish the effects of operational PDMPs

    from the effects of program that introduced mandatory access.

    5

  • 2.2 Data

    Data on foster-care cases are drawn from the Adotpion and Foster Care Analysis and Re-

    porting System (2000-2015). The Adoption and Foster Care Analysis and Reporting System

    (AFCARS) is a federally mandated data collection system providing case specific informa-

    tion on all children covered by the protections of Title IV-B/E of the Social Security Act

    (Section 427). The foster care data files contain information on child demographics including

    gender, birth date, race, and ethnicity.We calculated the number of foster-care cases by year

    and state.

    In addition, we collected county level controls from the Population and Housing Unit

    Estimates (PHUE, 2000-2015), the US Census (2000) and the American Community Survey

    (2001-2015). We use data from the PHUE to calculate child population and the share of

    children who were victims of child maltreatment. We include data on age composition,

    share of African-american population, share of Hispanic population, median income, gender

    composition, and unemployment rate drawn from the 2000 US Census and the 2001-2015

    American Community Survey. Finally, we collected data on the timing of adoption of other

    laws that may have affected prescription drug abuse (e.g., Good Samaritan laws, Doctor

    Shopping, Pain Clinic regulations, Physician exams laws, require ID laws, and tamper-

    resistant prescription form requirement laws).

    3 Empirical Specification

    To identify the dynamic response of foster care caseloads to drug monitoring programs we

    employ an event-study methodology and estimate the following equation:

    Childst = δs + φt +4∑−4

    γtMandates,t−τ +Xst + πs(δs ∗ t) + �st (1)

    6

  • where Childst is the number of new foster-care admission in year t in state s. Given the

    skewed distribution of foster care caseloads we use the inverse hyperbolic transformation

    (IHS) of foster cases as our dependent variable.2. Mandatest is an indicator for whether

    state i has introduced a mandatory PDMP in year t. Xst are a set of time-variant state

    level controls (age composition, share of African-american population, share of Hispanic

    population, median income, gender composition, and unemployment rate). All our estimates

    control for the natural logarithm of the child population (aged 0-18). δs are state fixed effects

    that capture time-invariant state level characteristics; φt are year fixed effects capturing the

    average national trend in child abuse; and δs ∗ t are state specific time trends. Standard

    errors are clustered at the state level. All estimates are weighted by child population.

    Dave et al. (2017) show that adopters of mandatory access provisions were very similar to

    states having a PDMP but who did not adopt such provisions. For this reason, to investigate

    the role of Mandatory access PDMPs, we restrict the analysis to states with an operational

    PDMP. The underlying assumption is that the states that had an operational PDMP but

    did not introduce a mandatory access provision provide a valid counterfactual for treated

    states (states with mandatory access provisions).

    We then investigate the effects of PDMPs and mandatory PDMPs in a standard differences-

    in-difference specification. Our identification strategy relies on the assumption that prior to

    the adoption of drug monitoring programs treated and untreated states were following par-

    allel trends and in the absence of programs implementation their path would have not been

    affected. In particular, we identify the effects of the program exploiting within-state changes

    in trends at the timing of implementation of drug monitoring programs. Consistent with

    the evidence from previous work on the effects of PDMPs on drug abuse (Buchmueller and

    Carey, 2017; Dave et al., 2017) and based on the dynamic response found in our event study

    that show the effects of mandatory PDMPs materializes two years after the enactment, we

    use a two-year lag to estimate our difference-in-difference model. Lagged effects are explained

    2In the Appendix, we show that results tend in the same direction when using the number of cases orthe number of cases per 1,000 individuals as alternative scales

    7

  • by the fact that it takes time for provider practices to diffuse across the state and there is a

    natural lag between increased prescription drug monitoring and the reduction in the overall

    supply of drugs.

    In practice, we estimate the following OLS model

    Childit = α + βMandatei,t−2 + ψXit + si + γt + �it (2)

    where Childit is the number of abuses or foster-care admission in year (or month) t

    in state i. Mandatei,t+2 is an indicator for whether state i has introduced a must-access

    Prescription Drug Monitoring Program by year t. Xit are a set of time-variant state level

    controls (age composition, share of African-American population, share of Hispanic pop-

    ulation, median income, gender composition, and unemployment rate). All our estimates

    control for the natural logarithm of the child population (aged 0-18). In addition, we control

    for the adoption of other laws that may have affected prescription drug abuse (e.g., Good

    Samaritan laws, Doctor Shopping, Pain Clinic regulations, Physician exams laws, require

    ID laws, and tamper-resistant prescription form requirement laws). Finally, we include year

    fixed effects, capturing the average national trend in child abuse, state fixed effects that cap-

    ture time-invariant county level characteristics, and state specific time trends. All estimates

    are weighted by child population.

    4 Main Results

    4.1 Trends and Descriptive Statistics

    Over the last few years there has been a sharp increase in the number of child removals.

    This trend closely mirrors the increase in fatal overdoses (Figure 1) and is largely driven by

    the increase in the cases associated with child neglect or caregiver drug-abuse (Figure 2).

    These figures parallel the dramatic surge in the distribution of prescription drugs across the

    8

  • US (Figure 3).

    Table 1 provides summary statistics of our main outcomes of interest. There were on

    average approximately 4,500 child removals in a state-year. The two main reason for removals

    are parental neglect and parental drug abuse. In 70% of the cases, removals were associated

    with parental neglect, while in 31% of the removals were associated with parental drug abuse.

    The share of removals associated with parental drug abuse rose from 22% in 2000 to 39% in

    2015.

    4.2 PDMPs and Foster Care Caseloads

    In Figures 4-5, we explore the dynamic response of child removals to the adoption of op-

    erational and then mandatory PDMPs. The event-study analysis shows that there was no

    significant effect of PDMP on child removals (Figure 4). On the contrary, following the adop-

    tion of must-access PDMPs we observe a marked decline in the number of child removals

    (Figure 5. The effect of the Mandates becomes significant two years after the adoption of the

    mandate. For this reason, our difference-in-difference strategy concentrates on the effects of

    must-access mandates two years after the implementation of the program.

    Table 2 presents the estimated effects of PDMPs on the number of children in foster care

    by main reason of removal. We find no evidence of significant effects of PDMP on child

    removals. However, mandatory PDMPs had significant effects on removals reducing both

    cases associated with neglect and physical abuse (Table 3). The magnitude of the effect is

    economically significant. The introduction of mandatory procedures reduced child removals

    by 8%. Foster-care cases associated with neglect and physical abuse reduced by respectively

    9% and 10%. These results imply a reduction of 467 removals per year or 0.27 less cases per

    1000 children (Table A.2, Panel A and B). Table A.3 illustrates the sensitivity of our main

    results to state-level time-varying controls and state specific time trends. While including

    state-level controls reduces the magnitude of the coefficient, the coefficient remains negative

    and statistically and economically significant. Using the method proposed by Oster (2017),

    9

  • we estimate that to explain away our main result on child removals the extent of selection on

    unobservables should be at least 14 times larger than the extent of selection on observables.

    We don’t find significant effects among Blacks (Table A.4), while the effects are larger

    among children aged 0-12 (Table A.5).

    Our baseline findings suggest that must-access PDMPs may substantially reduce the costs

    associated with child removals. With a back of the envelope calculation based on previous

    estimates on the costs of child removals, our results imply that must-access PDMPs reduced

    costs associated with child removals by approximately 476 million dollars per year, or 4.76

    billion in 10 years.

    5 Conclusion

    The recent opioid epidemic has dramatic implications for the children of opioid-dependent

    parents. As the opioid crisis spreads to urban counties and to different groups of the pop-

    ulation, more children are at higher risk of neglect, abuse or removal from their parental

    caregiver.

    Our paper contributes to the literature on the effectiveness of drug monitoring programs.

    We provide evidence that while operational PDMPs had no significant effects on foster

    care caseloads, mandatory PDMP substantially reduced cases of child removals (-10%) with

    significant reductions in the number of cases associated with neglect and physical abuse.

    Given the evidence on the long-lasting effects of child maltreatment and foster care, our

    findings suggest that the human capital, health and economic cost of the opioid crisis may

    be very large. At the same point, the effectiveness of programs monitoring drug-prescription

    supports the implementation of supply-side policies aimed at reducing the diffusion of opioid

    substances in the population. The indirect effects of these policies on child well-being are not

    negligible. Policy makers should take into account the human and financial costs of parental

    drug abuse when evaluating policy effectiveness and allocating resources across programs

    10

  • aimed at contrasting the opioid epidemic.

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    13

  • Figures and Tables

    Figure 1: Trends in Drug Related Deaths (2000-2015, CDC) and Drug-Related Foster CareCases

    Notes - Data on drug-related deaths are drawn from CDC database on detailed mortality causes. The Underlying Cause of

    Death database contains mortality and population counts for all U.S. counties. Data are based on death certificates for U.S.

    residents. Each death certificate identifies a single underlying cause of death and demographic data. Data on children who were

    assigned to foster care because of drug-related abuses are drawn from the Adoption and Foster Care Analysis and Reporting

    System (AFCARS), Foster Care File (2000-2016).

    14

  • Figure 2: Trends in Child Removals

    Notes - Data on children who were assigned to foster care because of drug-related abuses are drawn from the Adoption and

    Foster Care Analysis and Reporting System (AFCARS), Foster Care File (2000-2015).

    15

  • Figure 3: Retail Drug Distribution by Drug Code for U.S.

    Notes - Data are drawn from the Automated Reports and Consolidated Ordering System (ARCOS) provided by the U.S.

    Department of Justice Drug Enforcement Administration, Diversion Control Division. Data cover the period 1999-2015.

    16

  • Table 1: Summary Statistics, AFCARS (2000-2015)

    Mean Standard deviation# removals 4519.496 5190.235

    Reason:Neglect 3214.062 4151.742

    Drug abuse 1432.445 1902.54Physical abuse 960.282 1313.524Alcohol abuse 419.026 539.051Sexual abuse 321.487 474.670

    Notes - Data on children who were assigned to foster care because of drug-related abuses are drawn from the Adoption and

    Foster Care Analysis and Reporting System (AFCARS), Foster Care File (2000-2015). The table reports unweighted summary

    statistics by state and year for the main outcome variables in all US states. Data spans years 2000 to 2016.

    17

  • Figure 4: PDMP Event Study-Child Removal

    -.3-.2

    -.10

    .1C

    hild

    Rem

    oval

    s

    PDMP

    _3

    PDMP

    _2

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    0

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    2

    PDMP

    3

    -.3-.2

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    lect

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    es

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    _2

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    0

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    1

    PDMP

    2

    PDMP

    3

    Notes - All estimates include time-varying control at the state level for the share of female, Hispanic, African-American,

    White, foreign-born, non-citizen population, average family income (log), unemployment rate, children population (0-18), year

    and state fixed effects, state-specific time trends and the following laws/regulations: Good Samaritan laws, Doctor Shopping,

    Pain Clinic regulations, Physician exams, require ID, and tamper-resistant PF. Data on children who were assigned to foster

    care because of drug-related abuses are drawn from the Adoption and Foster Care Analysis and Reporting System (AFCARS),

    Foster Care File (2000-2016).

    18

  • Figure 5: Mandate Event Study-Child Removal

    -.3-.2

    -.10

    .1C

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    Mand

    ate_3

    Mand

    ate_2

    Mand

    ate_1

    Mand

    ate0

    Mand

    ate1

    Mand

    ate2

    Mand

    ate3

    Notes - All estimates include time-varying control at the state level for the share of female, Hispanic, African-American,

    White, foreign-born, non-citizen population, average family income (log), unemployment rate, children population (0-18), year

    and state fixed effects, state-specific time trends and the following laws/regulations: Good Samaritan laws, Doctor Shopping,

    Pain Clinic regulations, Physician exams, require ID, and tamper-resistant PF. Data on children who were assigned to foster

    care because of drug-related abuses are drawn from the Adoption and Foster Care Analysis and Reporting System (AFCARS),

    Foster Care File (2000-2016).

    19

  • Table 2: Effects of PDMP on Foster Cases (IHS)

    (1) (2) (3)IHS abuse cases IHS neglect cases IHS physical abuses

    PDMPt−2 -0.218 -0.205 -0.181(0.173) (0.176) (0.125)

    Observations 867 867 867Mean of Dep. Var. 8.531 8.156 6.855Std.Dev. of Dep. Var. 1.448 1.422 1.400

    Notes - All estimates include time-varying control at the state level for the share of female, Hispanic, African-American,

    White, foreign-born, non-citizen population, average family income (log), unemployment rate, children population (0-18), year

    and state fixed effects, state-specific time trends and the following laws/regulations: Good Samaritan laws, Doctor Shopping,

    Pain Clinic regulations, Physician exams, require ID, and tamper-resistant prescription form requirement. Data on children

    who were assigned to foster care because of drug-related abuses are drawn from the Adoption and Foster Care Analysis and

    Reporting System (AFCARS), Foster Care File (2000-2016).

    20

  • Table 3: Effects of Mandatory PDMP on Foster Cases (IHS)

    (1) (2) (3)IHS abuse cases IHS neglect cases IHS physical abuses

    Mandate t−2 -0.078** -0.100*** -0.089**(0.034) (0.034) (0.043)

    Observations 371 371 371Mean of Dep. Var. 8.711 8.338 6.890Std.Dev. of Dep. Var. 0.908 0.967 0.973

    Notes - All estimates include time-varying control at the state level for the share of female, Hispanic, African-American,

    White, foreign-born, non-citizen population, average family income (log), unemployment rate, children population (0-18), year

    and state fixed effects, state-specific time trends and the following laws/regulations: Good Samaritan laws, Doctor Shopping,

    Pain Clinic regulations, Physician exams, require ID, and tamper-resistant prescription form requirement. Data on children

    who were assigned to foster care because of drug-related abuses are drawn from the Adoption and Foster Care Analysis and

    Reporting System (AFCARS), Foster Care File (2000-2016).

    21

  • Appendix

    22

  • Table A.1: Effects of PDMP on Foster Cases

    (1) (2) (3)abuse cases neglect cases physical abuses

    Number of cases

    PDMPt−2 -348.367* -241.950 -125.614**(182.852) (178.239) (59.854)

    Observations 867 867 867Mean of Dep. Var. 4543 3235 945.9Std.Dev. of Dep. Var. 5247 4231 1307

    Cases per 1000 children

    PDMPt−2 -0.017 0.005 -0.021(0.063) (0.058) (0.020)

    Observations 867 867 867Mean of Dep. Var. 3.280 2.301 0.651Std.Dev. of Dep. Var. 1.473 1.170 0.482

    Notes - All estimates include time-varying control at the state level for the share of female, Hispanic, African-American,

    White, foreign-born, non-citizen population, average family income (log), unemployment rate, children population (0-18), year

    and state fixed effects, state-specific time trends and the following laws/regulations: Good Samaritan laws, Doctor Shopping,

    Pain Clinic regulations, Physician exams, require ID, and tamper-resistant PF. Data on children who were assigned to foster

    care because of drug-related abuses are drawn from the Adoption and Foster Care Analysis and Reporting System (AFCARS),

    Foster Care File (2000-2016).

    23

  • Table A.2: Effects of Mandatory PDMP on Foster Cases

    (1) (2) (3)abuse cases neglect cases physical abuses

    Number of cases

    Mandatet−2 -467.742** -394.359** -92.921***(181.931) (182.734) (27.222)

    Observations 371 371 371Mean of Dep. Var. 4563 3407 775.8Std.Dev. of Dep. Var. 5105 4517 982

    Cases per 1000 children

    Mandatet−2 -0.276** -0.202** -0.049***(0.125) (0.081) (0.016)

    Observations 371 371 371Mean of Dep. Var. 3.556 2.541 0.598Std.Dev. of Dep. Var. 1.554 1.306 0.317

    Notes - All estimates include time-varying control at the state level for the share of female, Hispanic, African-American,

    White, foreign-born, non-citizen population, average family income (log), unemployment rate, children population (0-18), year

    and state fixed effects, state-specific time trends and the following laws/regulations: Good Samaritan laws, Doctor Shopping,

    Pain Clinic regulations, Physician exams, require ID, and tamper-resistant PF. Data on children who were assigned to foster

    care because of drug-related abuses are drawn from the Adoption and Foster Care Analysis and Reporting System (AFCARS),

    Foster Care File (2000-2016).

    24

  • Table A.3: Must-access PDMP and Foster Care Admissions

    (1) (2) (3) (4)

    Child removals

    Mandatet−2 -587.285* -446.528 -611.210** -463.499**(303.077) (275.098) (290.749) (183.450)

    Observations 371 371 371 371Mean of Dep. Var. 4563 4563 4563 4563Std.Dev. of Dep. Var. 5105 5105 5105 5105

    Child removal cases associated with neglect

    Mandatet−2 -850.913** -509.274* -616.379* -390.716**(341.638) (293.915) (313.831) (184.450)

    Observations 371 371 371 371Mean of Dep. Var. 3407 3407 3407 3407Std.Dev. of Dep. Var. 4517 4517 4517 4517

    Child removal cases associated withPhysical Abuse

    Mandatet−2 106.755 -15.254 -31.471 -92.894***(92.016) (53.570) (71.080) (27.333)

    Observations 371 371 371 371Mean of Dep. Var. 775.8 775.8 775.8 775.8Std.Dev. of Dep. Var. 982 982 982 982

    State F.E. YES YES YES YESYear F.E. YES YES YES YESTime-varying state-levelc controls NO YES YES YESOther laws NO NO YES YESState specific time trends NO NO NO YES

    25

  • Table A.4: Effects of Mandatory PDMP on Foster Cases (Races)

    (1) (2) (3)IHS abuse cases IHS neglect cases IHS physical abuses

    Whites

    Mandatet−2 -0.040 -0.057* -0.056(0.039) (0.030) (0.050)

    Observations 371 371 371Mean of Dep. Var. 9.060 8.706 7.175Std.Dev. of Dep. Var. 0.911 0.962 0.960

    Blacks

    Mandatet−2 -0.024 -0.031 -0.086(0.055) (0.053) (0.067)

    Observations 371 371 371Mean of Dep. Var. 7.726 7.396 6.038Std.Dev. of Dep. Var. 1.602 1.621 1.690

    Notes - All estimates include time-varying control at the state level for the share of female, Hispanic, African-American,

    White, foreign-born, non-citizen population, average family income (log), unemployment rate, children population (0-18), year

    and state fixed effects, state-specific time trends and the following laws/regulations: Good Samaritan laws, Doctor Shopping,

    Pain Clinic regulations, Physician exams, require ID, and tamper-resistant PF. Data on children who were assigned to foster

    care because of drug-related abuses are drawn from the Adoption and Foster Care Analysis and Reporting System (AFCARS),

    Foster Care File (2000-2016).

    26

  • Table A.5: Effects of Mandatory PDMP on Foster Cases (Age groups)

    (1) (2) (3)IHS abuse cases IHS neglect cases IHS physical abuses

    Age 0-6

    Mandatet−2 -0.078** -0.099*** -0.096*(0.038) (0.035) (0.051)

    Observations 371 371 371R-squared 0.996 0.994 0.993Mean of Dep. Var. 8.169 7.810 6.218Std.Dev. of Dep. Var. 0.926 0.974 1.026

    Age 7-12

    Mandatet−2 -0.093** -0.115*** -0.071(0.038) (0.039) (0.043)

    Observations 371 371 371Mean of Dep. Var. 7.296 6.920 5.559Std.Dev. of Dep. Var. 0.912 0.972 0.968

    Age 13-18

    Mandatet−2 -0.068* -0.089* -0.119*(0.036) (0.048) (0.061)

    Observations 371 371 371Mean of Dep. Var. 6.928 6.500 5.324Std.Dev. of Dep. Var. 0.904 1.006 0.941

    Notes - All estimates include time-varying control at the state level for the share of female, Hispanic, African-American,

    White, foreign-born, non-citizen population, average family income (log), unemployment rate, children population (0-18), year

    and state fixed effects, state-specific time trends and the following laws/regulations: Good Samaritan laws, Doctor Shopping,

    Pain Clinic regulations, Physician exams, require ID, and tamper-resistant PF. Data on children who were assigned to foster

    care because of drug-related abuses are drawn from the Adoption and Foster Care Analysis and Reporting System (AFCARS),

    Foster Care File (2000-2016).

    27

    IntroductionBackground and DataPrescription Drug Epidemic and Policy ResponseData

    Empirical SpecificationMain ResultsTrends and Descriptive StatisticsPDMPs and Foster Care Caseloads

    Conclusion