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Neurologi
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Diagnosis dan Penatalaksanaan Meningitis OtogenikUSUIR/Manakin Repository
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USUIR Home (/xmlui/)→USU eJournals (UJ) (/xmlui/handle/123456789/25)→Majalah Kedokteran Nusantara (/xmlui/handle/123456789/144)→Vol. 39 No. 3 September 2006 (Suplemen) (/xmlui/handle/123456789/15102)→View Item
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dc.contributor.author Ritarwan, Kikingdc.date.accessioned 20101026T04:16:31Zdc.date.available 20101026T04:16:31Zdc.date.issued 20101026dc.identifier.issn 0216325xdc.identifier.other Lenny Anggrinadc.identifier.uri http://repository.usu.ac.id/handle/123456789/20672
dc.description.abstract
Otogenic meningitis can be defined as an acute bacterial meningitis that develop secondary to acute, chronic otitis media, chronic mastoiditis andrelated disorders. Many factors like bacterial virulence, release of cytokines (IL1,IL6, TNF alpha), change in blood brain barrier permeability andneuronal toxicity, contribute to the pathophysiology of the disease. Streptococcus pneumoniae is the predominant mocroorganism. Haemophylusinfluenzae dan P. aeruginosa being the second most important and staphylococcus aureus or other organism have been implicated rarely. Thediagnosis of otogenic meningitis should be based on clinical symptoms, signs and laboratory findings, especially CSF features. It is important toemphasize that any patient with suspected otogenic meningitis should be managed properly as soon as possible. The disease continues to be animportant cause of morbidity and mortality, and the introduction of antibiotic therapy and surgical procedures has significantly reduced both ismorbidity and mortality.
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dc.language.iso en en_USdc.subject otogenic meningitis en_USdc.subject acute bacterial meningitis en_USdc.subject diagnosis en_USdc.subject treatment en_USdc.title Diagnosis dan Penatalaksanaan Meningitis Otogenik en_USdc.type USU eJournals en_US
dc.description.abstract2
Meningitis otogenik didefinisikan sebagai meningitis bakterial akut akibat penjalaran infeksi sekunder dari otitis media akut dan kronik,mastoiditis kronik, dan labirinthitis suppuratif. Faktorfaktor penyebab meningitis otogenik banyak antara lain virulensi bakteri, pelepasan sitokin (interleukin1, interleukin6, TNF alpha), perubahan permeabilitas dari sawar darah otak, serta menimbulkan kerusakan dari selsel neuron.Streptococcus pneumonia merupakan bakteri yang predominant sebagai penyebab meningitis otogenik. Haemophylus influenzae dan P.aeruginosamerupakan penyebab kedua dan staphylococcus aureus ataupun mikroorganisma lain merupakan penyebab yang terjarang. Penegakkan diagnosismeningitis otogenik didasarkan kepada gejala dan tanda klinis dan pemeriksaan laboratorium, terutama analisa cairan serebrospinal. Yang paling penting penegakkan diagnosa dengan suspek meningitis otogenik adalah penanganan penderita secepat mungkin. Adanya pengobatan denganantibiotika yang adekuat serta tindakan operasi dapat menurunkan angka morbiditas dan mortalitas dari meningitis otogenik.
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This item appears in the following Collection(s)Vol. 39 No. 3 September 2006 (Suplemen) (/xmlui/handle/123456789/15102) [29]
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