CURRICULUM VITAE - Creighton University and Tenure...Page 3 of 33 Curriculum Vitae - Chauhan 2012 Summer Initiative for Teaching Excellence in the Health Sciences (SITE), Creighton

Page 1 of 33 Curriculum Vitae - Chauhan

CURRICULUM VITAE

A. Name Harsh Chauhan

B. College or School School of Pharmacy and Health Professions

C. Department Pharmacy Sciences

D. Date and Rank of First Appointment

January 31, 2011, Assistant Professor

E. Secondary Appointment(s)

(if any)

None

F. Years Granted Towards Tenure at Time

of Employment

0

G. Current Rank Assistant Professor

H. Date of Current Rank January 31, 2011

I. Date of Tenure Currently Applying for Tenure

J. Proposed Action Conferral of tenure and promotion to the rank

of Associate Professor

K. Years of Academic Service 5

L. Terminal Degree Ph.D. (Doctor of Philosophy in Pharmaceutics

and Drug Design)

M. Schools Attended

2005-2011 School of Pharmacy

Massachusetts College of Pharmacy and Health Sciences

(MCPHS) University, Boston, MA

1997-2001 College of Pharmacy

Meerut University, Modinagar

Uttar Pradesh, India

N. Degrees Earned

2011 Doctor of Philosophy (Ph.D.) in Pharmaceutics and Drug Design

2001 Bachelors of Pharmacy


O. Special Training Programs

2015 Grant Writing Workshop

University of Nebraska, Omaha, NE

Coordinator: Greenwood Consulting Group

Description: The workshop provided the process and strategies for

successful grant writing (NIH and NSF).

2014 Certificate in Formulation & Stabilization of Bio-therapeutics

Massachusetts Institute of Technology (MIT), Boston, MA

Faculty Coordinator: Dr. B. Trout, Dr. M. Manning

Description: This course discussed the significance and challenges

of bio-therapeutics focusing on globular proteins and antibodies.

2014 Certificate in Leadership for Science & Engineering Faculty


Faculty Coordinator: Dr. C. Leiserson, Dr. C. McVinney

Description: This course focused on human-centered strategies for

leading effective teams in technical academic environments.

2014 Weekend Retreat: Ignatian Spiritual Exercises

Deglman Center for Spirituality, Creighton University Retreat

Center, Griswold, Iowa

Description: Participated in an abbreviated version of the spiritual

exercises led by Fathers Carlson and Gillick for self-reflection and a

better understanding of the Ignatian tradition.

2013 Certificate in Controlled Release Technology


Faculty Coordinator: Dr. Robert Langer

Description: The program is designed for chemists, chemical

engineers, pharmaceutical scientists, and technical managers with an

interest in controlled release technology. The lectures reviewed the

recent advances in the art and science of controlled release

technology and to assess the prospects and directions of future

developments.

2012-2013 Blueline Mentoring Series

Creighton University, Omaha, Nebraska

Description: Participated in semester long sessions to understand the

basics of Blueline.

2012-2013 Experience Series

Creighton University, Omaha, Nebraska

Description: Participated in semester long sessions to understand the

technologies available at Creighton University and their application

in didactic teaching.


2012 Summer Initiative for Teaching Excellence in the Health

Sciences (SITE), Creighton University

Omaha, Nebraska

Description: Gained knowledge and skills for the scholarly

application of principles to teaching and evaluation of students for

professional pharmacy competencies.

P. Fields of Interest

1. Teaching

Pharmaceutics (Professional)

The science of preparing a drug entity into a biologically

compatible and acceptable form and then delivering that dosage

form to a living system.

Dosage Form Design and Drug Delivery Systems

(Professional)

This course comprises of non-sterile dosage forms and drug

delivery systems i.e. solid, liquid, semi-solid, aerosol, transdermal,

and emerging delivery systems. This course also emphasizes on the

development of nanoparticles and biopharmaceutical aspects of

delivery systems.

Non Sterile Dosage Form Design and Drug Delivery Systems

Lab (Professional)

Lab develops skills in extemporaneous compounding of solid,

liquid and semi-solid dosage formulations such as solutions,

suspensions, tablets, capsules, creams, pastes etc.

Novel Dosage Form Design and Drug Delivery Systems

(Graduate)

The course emphasizes on advance concepts of oral, parenteral,

topical /transdermal and controlled release novel drug delivery

systems.

Advanced Pharmaceutics

(Graduate, selected topics only)

The topic emphasizes on various law, principles and calculations of

solubility and distribution phenomena.

Analytical Technologies

(Graduate, selected topics only)

Microscopy techniques such as optical microscopy, scanning

electron microscopy, transmission electron microscopy, atomic

force microscopy etc. are covered.


2. Research

Formulation of Poorly Soluble Drugs

The development, evaluation, characterization, and delivery of

poorly water soluble drugs through oral and intranasal route for the

diagnosis, treatment, and/or prevention of diseases.

Phytochemicals/Food Supplements

Designing of novel drug delivery systems for poorly water soluble

phytochemicals such as curcumin, resveratrol, quercetin etc. and

their combinations for enhanced anti-oxidant and anti-cancer

activities.

Molecular Modeling/Machine Learning

Utilization of machine learning and molecular modeling approaches

as a tool for the prediction of the properties of drugs/phytochemicals

and their toxicities.

Novel Drug Delivery Systems

The development and evaluation of amorphous and nano-

particulate systems that can enhance the solubility, control the rate

of drug release and target the drug from a drug

product/formulations. Qualitative and quantitative characterization

of these systems using X-ray powder diffraction, modulated

differential scanning calorimetry, infrared and Raman

spectroscopy, scanning electron microscopy techniques etc.

Q. Professional Employment

2011-Present Assistant Professor

Department of Pharmacy Sciences

School of Pharmacy and Health Professions

Creighton University

Omaha, Nebraska

2005-2011 Teaching Assistant

Department of Pharmaceutical Sciences

Massachusetts College of Pharmacy and Health

Sciences University

Boston, MA

2005-2006 Research Assistant (Part Time)

Longwood Pharmaceutical Research,

Boston, MA


2004-2005 Medical Detailing Officer

Nestle, India

2003- 2004 Territory Manager

Eli Lilly India, India

R. Consultantships and Professional Services

2006-2008 Worked as Visiting Scientist at Vertex Pharmaceuticals, Cambridge,

MA to develop amorphous systems and in-vitro dissolution

apparatus to study conventional drugs (part of Ph.D. thesis).

Developed technologies were applied to new molecules developed

by the company.

S. Organizations

2005-Present American Association of Pharmaceutical Scientists

(AAPS) Member

2011-Present American Chemical Society (ACS) Member

2011-Present American Association of College of Pharmacy

(AACP) Member

2016-Present Rho Chi Society, Alpha Alpha Chapter Member

T. Fellowships and Honors

1998-2000 Awarded undergraduate research fellowship during B. Pharmacy

program to carry out research on UV analysis of various drugs with

various polymer matrices.

U. Awards and Prizes

2015 Scholarly Achievement Award, School of Pharmacy and Health

Professions, Creighton University

2014 American Association of Pharmaceutical Scientists

(AAPS) Travelship Award

2008 AAPS-North Eastern Regional Discussion Group (NERDG),

Research Poster Award, 3rd prize

2008 Massachusetts College of Pharmacy and Health Sciences

(MCPHS) Poster Day, 1st Prize


V. Grants

Submitted and Funded Grants

1. Status: Funded

Title: Bulk Paracellular Transport of Drug Carriers in the Nasal Cavity

Funding Source: Health Future Foundation, Creighton University

Amount: $48,709

Dates: July 01, 2016-June 30, 2017

Role: Co-Investigator

Principal Investigator: Dr. Anthony Kincaid

Other Co-Investigator: Dr. Justin Tolman

Purpose: The overall project goal is to understand the transport of drug

through nasal route.

2. Status: Funded to Pharm. D student

Title: Formulation and In-vitro Characterization of Nanoparticulate

Systems for Intranasal Delivery

Funding Source: Student summer research program, School of

Pharmacy and Health Professions (SPAHP),


Amount: $3,000, Student summer salary (TBD)

Dates: September 01, 2016-August 31, 2017

Role: Faculty Mentor

Other Faculty Mentor: Dr. Anthony Kincaid

Purpose: Acquire preliminary data for intranasal delivery of different drug

carriers.

3. Status: Funded

Title: Novel Oral Delivery Systems for Anticancer Phytochemical

Curcumin

Funding Source: Creighton Undergraduate Research and Scholarship

funds (CURAS), Creighton University

Amount: $2,000

Dates: May 01, 2015-April 30, 2016

Role: Principal Investigator

Purpose: Design and characterize novel amorphous formulations of curcumin

with higher solubility and stability. Provide undergraduate student

training and guidance on bench research, literature search and data

analysis.



Title: Intranasal Delivery of Synergistically Active Curcumin-

Resveratrol for High Bioavailability

Funding Source: Student summer research program, SPAHP,


Amount: $3,000, Student summer salary (Zalak Patel)

Dates: May 01, 2015-August 31, 2015


Other Faculty Mentor: Dr. Anthony Kincaid

Purpose: Acquire preliminary data for intranasal delivery of curcumin and

resveratrol.

5. Status: Funded

Title: Development of Oral Drug Delivery Systems for Poorly Soluble

Anticancer Drugs Based on Drug-Polymer Interactions

Funding Source: Dr. George F. Haddix President's Faculty Research

Fund, Creighton University, Creighton University

Amount: $5,000

Dates: February 15, 2015-February 14, 2015


Purpose: Drug polymer interactions strength between various anticancer

drugs and polymers were determined. Based on stronger interaction

strength oral drug formulations were prepared, characterized and

evaluated.


Title: Computational Predictions for the Development of Novel

Anticancer Formulations

Funding Source: Student Summer Research Program, SPAHP,


Amount: $3,000, Student summer salary (Jonathan Bernick)

Dates: May 01, 2012-August 31, 2013


Purpose: Prediction of glass forming ability by computational tool using

physiochemical properties (melting point, molecular weights, log D

etc.) for the successful development of poorly soluble anticancer

drugs will be attempted in this research.


Submitted and Unfunded Grants 1. Status: Not Funded

Title: Phytochemical Polymer Interactions to Develop Novel

Pharmaceuticals

Funding Source: Dr. George F. Haddix President's Faculty Research Fund,


Amount: $4,997



Purpose: The goals of this proposal were to rationally study the interactions

of various phytochemicals and develop them into delivery systems.

2. Status: Not Funded (Reviewed, Scored and will be Resubmitted)

Title: Hepatotoxicity Predictions of Dietary Supplements by Machine-

Learning Algorithms

Funding Source: National Institutes of Health Academic Research Enhancement

Award (Parent R15: PA-13-313)

Amount: $224,676

Dates: July 01, 2015 – June 30, 2017


Co-Investigator: Dr. Amit Tiwari, Dr. Philip Gregory

Purpose: The grant involves compiling a database of small-molecule drugs

and dietary supplements and their hepatotoxic statuses, and using

this database as input for machine-learning algorithms, which will

use the data to construct decision functions that will predict the

hepatotoxic potential of dietary supplements as functions of the

chemical structures and physiochemical properties of such

supplements, and verify these predictions by in-vitro and in-vivo

investigation.

3. Status: Not Funded

Title: Dissolution Methods for Long-acting Periodontal Drug Products

(U01)

Funding Source: FDA

Amount: $250,000

Dates: July 01, 2015 – June 30, 2017

Role: Co-Investigator

Principal Investigator: Dr. Alekha Dash


Purpose: The proposal was to develop a dissolution technique that has the

potential to successfully identify any variances in terms of

bioequivalence between these long-acting marketed products and

their generic versions for periodontal formulations


Title: Intranasal Delivery of Curcumin-Resveratrol: Synergistically

Active Anticancer System with High Bioavailability

Funding Source: LB692 - NE Tobacco Settlement Biomedical Research

Development New Initiative Grant

Amount: $75,000

Dates: July 01, 2015-June 30, 2016


Co-Investigator: Dr. Anthony Kincaid, Dr. Justin Tolman, Dr.

Alekha Dash

Purpose: Prepare evaluate and characterize a novel concentrated amorphous

curcumin-resveratrol system for intranasal delivery on in vitro

cancer cell lines for their anti-proliferative properties and carry out

pharmacokinetic and histological studies to establish the

mechanism(s) of curcumin-resveratrol transepithelial transport, and

measure the amount and concentration of the formulation that

reaches the blood and other tissues.

5. Status: Not Funded (Also, resubmitted in 2016, not funded)

Title: MRI: Acquisition of a Multi-Purpose X-ray Diffractometer for

Structural Characterization

Funding Source: NSF

Amount: $300,000

Dates: 2015-2016

Role: Senior Personnel

Principal Investigator: Dr. Andrew Barauth

Other Senior Personnel: Dr. Erica Villa, Dr. Sidebottom

Purpose: The grant proposed acquisition of X-ray characterization across a

variety of disciplines at CU, including physics, chemistry, material

science, energy science, and pharmacy science.



Title: Converting Conventional Phytochemicals into Novel

Pharmaceuticals

Funding Source: Haddix Grant, Creighton University

Amount: $5,000



Purpose: Phytochemicals such as curcumin, resveratrol, quercetin and

piperine were proposed to screen for the development of

formulations using In-vitro assays.


Title: Novel Oral Targeted Drug Delivery System for Bevacizumab in

Treating Colon Cancer

Funding Source: American Association of Pharmaceutical Scientists, New

Investigator Application

Amount: $10,000

Dates: December 01, 2014-November 30, 2015


Purpose: Nano particulate formulations were proposed for Bevacizumab for

colon cancer targeting.


Title: Converting Conventional Phytochemicals into Novel

Pharmaceuticals: Solubility and Stability enhancement using weak

phytochemical-polymer interactions

Funding Source: Nebraska EPSCoR Career Grant

Amount: $20,000

Dates: January 01, 2014-September 30, 2015


Purpose: Nanoparticle formulations of Resveratrol and Quercetin and their

In-vitro analysis were proposed.



Title: Otoprotective Compound for Prevention and Treatment of Noise-

and Drug-Induced Hearing Loss

Funding Source: Department of Defense

Amount: -

Dates: 2014-2015

Role: Consultant

Principal Investigator: Dr. Sonia Sanchez

Co-PI’s: Dr. Chris Destache, Dr. Martha Nunn, Dr. Kim Galt

Purpose: Consultant for drug formulations of compounds for treatment of

hearing loss.


Title: Development of Novel Formulation Using Drug Polymer

Interactions


Amount: $20,000

Dates: July 01, 2013-June 30, 2014


Purpose: Design delivery system using biodegradable polymers such as PEG,

PLGA for poorly soluble drugs.


Title: Development of Novel Solubility Approaches Based on Drug

Excipients Interactions.


Amount: $20,000

Dates: July 01, 2012-June 30, 2013


Purpose: Explore the solubility enhancing efficiency of various poorly

soluble utilizing interactions between drugs and FDA approved

polymers.



Title: Stabilization of Nanoparticles During Lyophilization Using

Polymeric Excipients

Funding Source: AACP 2012-2013 New Investigator Application

Amount: $10,000

Dates: January 01, 2012- December 31, 2013


Purpose: The proposed goal of the project was to develop stable solid lipid

nanoparticles for hard to formulate potential drugs and to determine

the crystallization/aggregation inhibition efficiency of various

polymeric excipients during lyophilization.

Submitted Grants That Are In Review

1. Status: Under Review

Title: Ionically Complexed and Miscible Food Supplements-Delivery

Matrices as Safe and Potent Anticancer Pharmaceuticals

Funding Source: Parent R15, National Cancer Institute, NIH

Amount: $379,276

Dates: April 01, 2017-March 31, 2019


Co-Investigator: Dr. Amit Tiwari, University of Toledo

Purpose: The expected outcome of this project is a set of delivery systems for

curcumin and resveratrol that can be investigated in vivo for their

anticancer properties, and eventually developed as oral anticancer

agents. This research will be used as a foundation for the

development of other supplement-amorphous solid dispersion

combinations as therapeutic agents. The long term goals of the grant

is to include the discovery of new cancer treatments and

improvements in the use of existing therapies.

W. Scholarship

Book Chapters

1. Prasad, Dev and Chauhan, Harsh; “Excipients Utilized in Ocular Drug Delivery”, Nano

Bio Materials for Ophthalmic Drug Delivery, Springer, 2016 (Proof read completed).

Role: Co-Author

2. Chauhan, Harsh; Bernick, Jonathan; Prasad, Dev and Masand, Vijay; “ANN on Target

Validation as Robust Tool in Drug Discovery and Development”, Artificial Neural

Network for Drug Design, Delivery and Disposition, Edited by Puri, Pathak, Sutariya,


Tipparaju, Moreno, Release Date 22 Oct 2015, Academic Press, Print Book ISBN

:9780128015599, eBook ISBN :9780128017449.

Role: First Author

3. Prasad, Dev and Chauhan, Harsh; “Nanotoxicity of Polymeric and Solid Lipid

Nanoparticles”, in Bio-interaction of Nano Materials, CRC Press, ISBN 9781466582385,

2014.

Role: Co-Author

4. Gu, Chong-Hui; Chauhan, Harsh; and Kuldipkumar, Anuj; “Factors Affecting Drug

Absorption and Disposition in a System”, Pharmaceutics: Basic Principles and Application

to Pharmacy Practice, ISBN: Print Book ISBN: 9780123868909; eBook ISBN:

9780123868916, Elsevier 2013.

Role: Co-Author

Publications (In-process)

1. Gala, Urvi and Chauhan, Harsh; Dissolution Enhancement of Curcumin and Resveratrol

using Cyclodextrins (2016).

This manuscript represents thesis research from graduate students in my

laboratory. A draft manuscript has been completed and is also being revised. I

plan submission to the journal “Pharmaceutical Research” (3.952 Impact Factor).

2. Meng, Fan and Chauhan, Harsh; Small Scale Screening to Investigate the Ability of

Polymers to Influence Physicochemical Properties of Drugs (2016).

This manuscript represents the thesis research of one of the master’s student from

my laboratory. Data collection is complete and a draft manuscript has been

completed. I plan submission to the journal “Molecular Pharmaceutics” (4.384

Impact Factor).

3. Trivino, Anne and Chauhan, Harsh; Solubility Enhancement of Poorly Soluble Drug

Flutamide (2016).

This manuscript represents the thesis research of one of the master’s student from

my laboratory. I plan submission to the journal “Drug Development and Industrial

Pharmacy” (2.101 impact Factor).

4. Shantanu, Chandratre; Chauhan, Harsh and Alekha Dash; Glyceryl Monooleate (GMO);

Monograph; Analytical Profiles of Drug Substances and Excipients, Edited by Harry G.

Brittain; (2016).

This monograph is completed and submitted to Dr. Alekha Dash, corresponding

author of the monograph.


Publications (Peer reviewed) *Citation Source: Google Scholar

1. Saad, A. Hussain; Amal, A. Sulaiman; Curt, Balch; Chauhan, Harsh; Qasim, M. Alhadidi

and Amit, K. Tiwari; “Natural Polyphenols in Cancer Chemoresistance” Nutrition and

Cancer, 68,6 (2016):879-891.

Impact factor: 2.241

Role: Co-Author

*Citation: Recently published

2. Prasad, Dev; Chauhan, Harsh and Atef, Eman; “Role of Molecular Interactions for

Synergistic Precipitation Inhibition of Poorly Soluble Drug in Supersaturated Drug–

Polymer–Polymer Ternary Solution” Molecular Pharmaceutics. 13, 3(2016): 756-765.


Role: Co-Author

Citation: 2

3. Farah, Shrouq I.; Abdelrahman, Abd Almonem; North, E. Jeffrey and Chauhan, Harsh;

“Opportunities and Challenges for Natural Products as Novel Antituberculosis Agents”

ASSAY and Drug Development Technologies. 14, 1 (2016): 29-38.

Impact factor: 1.53

Role: Corresponding Author

Citation: Recently published

4. Meng, Fan; Dave, Vivek and Chauhan, Harsh; "Qualitative and Quantitative Methods to

Determine Miscibility in Amorphous Drug–Polymer Systems." European Journal of

Pharmaceutical Sciences 77 (2015): 106-111.



Citation: 9

5. Meng, Fan; Gala, Urvi and Chauhan, Harsh; "Classification of Solid Dispersions:

Crrelation to (i) Stability and Solubility (ii) Preparation and Characterization Techniques”

Drug Development and Industrial Pharmacy 41, 9(2015):1401-1415.



Citation: 5

6. Chauhan, Harsh; Mohapatra, Sarat; Munt, Daniel J; Chandratre, Shantanu and Dash,

Alekha; "Physical-Chemical Characterization and Formulation Considerations for Solid

Lipid Nanoparticles” AAPS PharmSciTech 0,0 (2015):1-12.


Role: Primary Author

Citation: 2

7. Gala, Urvi; Chuong, Monica C.; Varanasi, Ravi and Chauhan, Harsh; "Characterization

and Comparison of Lidocaine-Tetracaine and Lidocaine-Camphor Eutectic Mixtures


Based on their Crystallization and Hydrogen-Bonding abilities." AAPS PharmSciTech 16,

3 (2015): 528-536.



Citation: 1

8. Meng, Fan; Trivino, Anne; Prasad, Dev and Chauhan, Harsh; "Investigation and

Correlation of Drug Polymer Miscibility and Molecular Interactions by Various

Approaches for the Preparation of Amorphous Solid Dispersions." European Journal of

Pharmaceutical Sciences 71 (2015): 12-24.



Citation: 17

9. Gala, Urvi and Chauhan, Harsh; "Principles and Applications of Raman Spectroscopy in

Pharmaceutical Drug Discovery and Development." Expert Opinion on Drug Discovery

10, 2 (2015): 187-206.



Citation: 7

10. Kathe, Niranjan; Henriksen, Brian and Chauhan, Harsh; "Physicochemical

Characterization Techniques for Solid Lipid Nanoparticles: Principles and Limitations”

Drug Development and Industrial Pharmacy 40, 12 (2014): 1565-1575.



Citation: 11

11. Prasad, Dev; Chauhan, Harsh and Atef, Eman; "Amorphous Stabilization and Dissolution

Enhancement of Amorphous Ternary Solid Dispersions: Combination of Polymers

Showing Drug–Polymer Interaction for Synergistic Effects” Journal of Pharmaceutical

Sciences, 103, 11 (2014): 3511-3523.

Impact factor: 3.35

Role: Co-Author

Citation: 19

12. Chauhan, Harsh; Kuldipkumar, Anuj; Barder, Timothy; Medek, Ales; Gu, Chong-Hui

and Atef, Eman; "Correlation of Inhibitory Effects of Polymers on Indomethacin

Precipitation in Solution and Amorphous Solid Crystallization Based on Molecular

Interaction” Pharmaceutical Research, 31 2 (2014): 500-515.



Citation: 20


13. Gala, Urvi and Chauhan, Harsh; “Taste Masking Techniques in Pharmaceutical

Industry”. American Pharmaceutical Review, 17 (4), (2014), 24-29.

Impact Factor: None


Citation: 1

14. Gala, Urvi; Pham, Hoang and Chauhan, Harsh; "Pharmaceutical Applications of Eutectic

Mixtures” Journal of Developing Drugs, 2013.

Impact factor: 0.93


Citation: 2

15. Masand, Vijay H; Mahajan, Devidas T; Hadda, Taibi Ben; Jawarkar, Rahul D; Chavan,

Hemant; Bandgar, BP and Chauhan, Harsh; "Molecular Docking and Quantitative

Structure–Activity Relationship (QSAR) Analyses of Indolylarylsulfones as HIV-1 Non-

Nucleoside Reverse Transcriptase Inhibitors” Medicinal Chemistry Research 23, 1 (2014):

417-425.


Role: Co-author

Citation: 8

16. Prasad, Dev; Chauhan, Harsh and Atef, Eman; "Studying the Effect of Lipid Chain

Length on the Precipitation of a Poorly Water Soluble Drug from Self‐Emulsifying Drug

Delivery System on Dispersion into Aqueous Medium” Journal of Pharmacy and

Pharmacology,65,8 (2013): 1134-1144.


Role: Co-Author

Citation: 13

17. Chauhan, Harsh; Hui‐Gu, Chong and Atef, Eman; "Correlating the Behavior of Polymers

in Solution as Precipitation Inhibitor to its Amorphous Stabilization Ability in Solid

Dispersions” Journal of Pharmaceutical Sciences, 102, 6 (2013):1924-1935.

Impact factor: 3.35


Citation: 35

18. Atef, Eman; Chauhan, Harsh; Prasad, Dev; Kumari, Dunesh and Pidgeon, Charles;

"Quantifying Solid-State Mixtures of Crystalline Indomethacin by Raman Spectroscopy

Comparison with Thermal Analysis” ISRN Chromatography 2012 (2012):1-6.

Impact factor: None

Role: Co-author

Citation: 11

19. Atef, Eman; Chauhan, Harsh; Ceresia, Michelle and Pidgeon, Charles; " Using Raman

Spectroscopy in Tablet Moisture Surface Analysis: Tablet Surface Markers” Journal of

Pharmaceutical and Biomedical Analysis 53, 4, (2010): 852-85.



Role: Co-Author

Citation: 5

20. Chauhan, Harsh and Eman, Atef; " Quality of Progesterone Suppositories Prepared by

FIRST-Progesterone Vaginal Suppository 50 Kit or Traditional Compounding Method: In

Vitro Comparison” International Journal of Pharmaceutical Compounding, 13, 4,

(2009):342-344.

Impact factor: None


Publications (Non Peer Reviewed)

1. Trivino, Anne and Chauhan, Harsh; “Drug-Excipient Compatibility for the Formulation

Development of Solid Lipid Nanoparticles”. American Pharmaceutics Review. 2015;

18(1).

2. Barger, N.; Lin, L. Potdar; S., Skultety; P., Kadri; B. V.; Chauhan, Harsh and Koziatek,

K.; “Formulation Development Roundtable”. Pharmaceutical Outsourcing, 14(1) (2013).

(Roundtable).

Presentation: Invited (Podium: National)

Chauhan H; Invited presenter at 6th Symposium on “Solubility Enhancement Utilizing

Pharmaceutical Melt -Extrusion and Spray-Drying Techniques”, Piscataway, NJ, Evonik,

2015.

Presentation: Invited (Webinar: International)

Chauhan H; “Formulation consideration of Solid Lipid Nanoparticles” (Attended by 86

scientists globally), AAPS Webinar July 2014.

Presentation: Invited (Podium: Regional)

Chauhan H; “Novel Drug Delivery Systems for Poorly Soluble Compounds”, Augustana

College, Sioux City, SD, 2013.

Presentations (Poster: International)

1. Gumireddy Ashwini, Chauhan H, Formulation of Soluble Binary and Novel Ternary

Amorphous Complexes for Anticancer Activity, American Association of Pharmaceutical

Scientists annual meeting, Denver, Colorado, USA, November 13-17, 2016 (Accepted).

2. Meng F, Rana S, Natarajan A, Chauhan H, Effect of polymers on the crystallization

tendency of poorly soluble drugs and its correlation to amorphization in solid dispersions,

American Association of Pharmaceutical Scientists annual meeting, Orlando, Florida,

USA, October 25-29, 2015.


3. Gala U, Chauhan H, Preparation and characterization of novel curcumin-resveratrol-

hydroxy propyl beta cyclodextrin, American Association of Pharmaceutical Scientists

annual meeting, Orlando, Florida, USA, October 25-29, 2015.

4. Meng, F., Chauhan H., Experimental and Theoretical correlation of Glass transition

temperature: Role of Molecular Interactions. AAPS Annual Meeting, San Diego, 2014

5. Gala U, Chauhan H. Physical-Chemical Characterization of Cylodextrin Based Ternary

Complexes Containing Two Poorly Water Soluble Anti-Cancer Agents. AAPS Annual

Meeting and Exposition, San Diego, 2014.

6. Gala U, Chauhan H. Dissolution Enhancement of Curcumin and Resveratrol Combination

Using Cyclodextrins. AAPS Annual Meeting and Exposition, San Diego, 2014.

7. Chauhan H, Gala U, Meng F. Characterization of Binary (Drug-Polymer) and Ternary

(Drug-Drug-Polymer) Solid Dispersions: Role of Low Polymer Concentrations on Their

Stabilization, AAPS Annual Meeting and Exposition, San Diego, 2014

8. Gala U, Chauhan H. Characterization of Lidocaine-Tetracaine and Lidocaine-Camphor

Eutectic Mixtures Based on their Hydrogen Bonding and Crystallization Abilities. AAPS

Annual Meeting and Exposition, San Diego, 2014

9. Dev Prasad, Chauhan H, Eman Atef, Synergistic effect of molecularly interacting

polymers in stabilization ternary solid dispersions, AAPS annual meeting 2013.

10. N. J. Kathe, E.J. Haas, Chauhan H., J. Fujita, B. S. Henriksen, Synthesis and Holistic

Characterization of Glucogenic Amino Acid Complexes as Ergogenic Aids, AAPS annual

meeting 2013.

11. Chauhan H., Monica Chuong, Ravi Varanasi, Characterization of Lidocaine-Tetracaine

and Lidocaine-Tetracaine HCl Mixtures for Transdermal Delivery, AAPS annual meeting

2013.

12. Anne Trivino, Bernick Jonathan, Chauhan H., Molecular Modeling of Drug Polymer

Interactions for Amorphous Stabilization of Poorly Soluble Anticancer Drug Flutamide,

AAPS annual meeting 2013.

13. Dev Prasad, Bernick Jonathan, Chauhan H., In-silico predictions for the development of

poorly soluble anticancer drugs as amorphous systems, 244 ACS National meeting; 2012

14. Dev Prasad, Chauhan H., Eman Atef, Understanding drug-polymer interactions for the

amorphous stabilization of high melting crystalline compound with various polymers, 244

ACS National meeting; 2012

15. D. Prasad, Chauhan H., Eman Atef, Stabilization of ternary solid dispersions at high drug

load using molecularly interacting polymers, AAPS Annual meeting 2012


16. Shantanu Chandratre, Chauhan H., Alekha K. Dash, Crystallization inhibition of GMO-

chitosan nanoparticles during lyophilization process, AAPS Annual meeting 2012

17. M. Nagarsenker, Chauhan H., Thermal characterization of solid lipid Nanoparticles

containing Gelucire 44/14 and Gelucire 50/13, AAPS Annual meeting 2012

18. Chauhan H., Physicochemical properties based computational predictions to classify drugs

as glass formers, AAPS Annual meeting 2012

19. Chauhan H., Mohapatra Sarat, Mistry Pinal, Munt Dan, Dash Alekha, Physical

Characterization of Glyceryl Monooleate (GMO) During lyophilisation Process, AAPS

annual meeting, 2011

20. Prasad Dev, Chauhan H., Atef Eman, Investigating the Effect of Various Oils on

Pecipitation Inhibition of Indomethacin from Self-Emulsifying Drug Delivery Systems

(SEDDS) on In-vitro Dilution, AAPS annual meeting , 2010

21. Atef Eman, Chauhan H., Prasad Dev , Quantifying Solid Mixture of Alpha and Beta

Indomethacin Using Raman and Differential Scanning Calorimetry, AAPS annual meeting

, 2010

22. Atef Eman, Chauhan H., Ceresia Michelle, Pidgeon Charles, Indirect Measurement of

Tablet-Surface Water Adsorption Using Raman Active Vibrations of the Excipient

Lactose, AAPS annual meeting 2009

23. Chauhan H., Atef Eman, Gu Chong-Hui, Preparation and characterization of Griseofulvin

solid dispersions with various polymers, AAPS annual meeting 2009

24. Chauhan H., Gu Chong-Hui, Atef Eman, Effect of polymers on dipyridamole

precipitation in solution., AAPS annual meeting 2009

25. Chauhan H., Prasad Dev, Atef Eman, Effect of PVP K 90 on indomethacin, dipyridamole

and progesterone crystallization in Solution at different super saturations, AAPS annual

meeting 2009

26. Chauhan H., Atef Eman, Gu Chong-Hui, Effect of Polymer on Drug Precipitation in

Solution and its Implication to Amorphous Stabilization, AAPS annual meeting 2008

Presentations (Poster: Regional)

1. Anne Trivino, Jonathan P Bernick, Chauhan H., Effect of lipids and surfactant miscibility

on the particle size of flutamide solid lipid nanoparticles, ACS regional meeting, Omaha,

2012

2. Jonathan P Bernick, Anne Trivino, Chauhan H., Molecular modeling of drug polymer

interactions: Correlation to precipitation inhibition and amorphous stabilization of poorly

soluble anticancer drug, ACS regional meeting, Omaha, 2012


3. Chauhan H., Prasad Dev, Atef Eman, Gu Chong-Hui, Preparation and characterization of

acidic, basic and neutral drug solid dispersions with various polymers having different

physicochemical properties, AAPS-NERDG meeting 2010.

4. Chauhan H., Atef Eman, Effect of different polymers, supersaturation and seeding on the

morphology of a weak acids and weak bases precipitating from solution, AAPS-NERDG

meeting 2009

Presentations (Poster: Local)

1. Gala U, Chauhan H. ‘Characterization and Comparison of Lidocaine-Tetracaine and

Lidocaine-Tetracaine Hydrochloride Eutectic Mixtures’. St. Albert’s Research Day,

Omaha, 2014. (Updated data was also presented at AAPS annual meeting)

2. Meng, F., Chauhan H., Development of amorphous solid dispersion formulations of

curcumin. Midwest Student Biomedical Research Forum (MSBRF), Omaha, 2013.

(Updated data was also presented at AAPS annual meeting)

3. Bernick Jonathan, Chauhan H., In-silico predictions for the development of poorly soluble

amorphous drugs, Midwest student biomedical research forum, 2012.

4. Chandratare Shantanu, Dhapare Sneha, Chauhan H., Solubilization and stabilization of

poorly soluble drugs, Nebraska EPSCoR, 2011

5. Prasad Dev, Chauhan H., Atef Eman, To prepare and stabilize amorphous solid

dispersions using Eudragits, AAPS-MCPHS poster day 2008

6. Chauhan H., Atef Eman, Screening of different polymers for stabilization of

Indomethacin solid dispersions, AAPS-MCPHS poster day 2008

7. Chauhan H., Atef Eman, Preparation of soluble and stable Indomethacin Solid Dispersion

with PVP K 90 as a polymer and Pluronic as a surfactant, AAPS-MCPHS poster day 2008

8. Chauhan H., Atef Eman, In-vitro comparison of progesterone suppositories prepared by

FIRST-Progesterone VGS 50 Kit to Traditionally Compounded Suppositories Method,

Reed Conference 2007

9. Chauhan H., Atef Eman, Gu Chong-Hui, Quantification of interaction between drug and

polymeric excipients and its implications to precipitation inhibition and amorphous

stabilization, Vertex Intern poster presentation 2007

10. Chauhan H., Sanghvi Tapan, Dissolution Model for VX -950: Supersaturation and In vitro

Studies. Development of new in vitro dissolution model, Vertex Intern poster presentation

2006.


X. Teaching

2016-2017: Professional

Course Name Course Number Level Role Hours

PHA 339 (Updated

course of previously

offered PHA 327)

Dosage form design and

drug delivery systems

Required first year

pharmacy course

Instructor of

Record

2.5

Description: This course provides an introduction to different pharmaceutical dosage forms and

drug delivery systems. This course comprises of non-sterile dosage forms and drug delivery

systems i.e. solid, liquid, semi-solid, aerosol, transdermal, and emerging delivery systems. This

course also emphasizes on the development of nanoparticles and biopharmaceutical aspects of

delivery systems.

Enrollment:

Campus: 77

Distance: 61

Total: 138

Teaching Innovation: Short videos of important concepts were created using Echo 360 personal

captures. Cumulative exam was introduced into the course based on student feedback. Newer

topics on novel drug delivery systems (especially nanotechnology) were introduced. Matching

type questions were introduced in the exams.


PHA 339 (Lab

Component)

Dosage form design and

drug delivery systems

Required first year

pharmacy course

Instructor of

Record

0.5

Description: The lab part of the course will highlight the concepts and applications of non-sterile

compounding of dosage forms and will have a lab component to simulate the theoretical learning

with actual compounding practice.

Enrollment: (Distance student will take the course during summer 2016)

Campus: 77

Total: 77

Teaching Innovation: First time non sterile lab components (8 labs) were introduced as a part of

the course. Previously, only three labs were offered in a different skills lab course. Non-sterile

skills lab activities re-reemphasizing the content covered in the course. They were designed and

introduced in the labs.


2016-2017: Graduate


MPS 602 Analytical aspects of

pharmaceutical sciences

research

Graduate first year

pharmacy required

course

Instructor

(Microscopic

applications)

3

Description: This course covers the theory, instrumentation and application of commonly used

laboratory equipment’s, including, absorption spectroscopy (UV, visible and infrared); mass

spectroscopy (MS), high pressure liquid chromatography (HPLC) and nuclear magnetic resonance

(NMR), amongst others.

Enrollment:

Campus: 4

Teaching Innovation: Animated videos of microscopic techniques were added to the course.


MPS 692 Directed Independent

Study

Graduate first year

pharmacy course

Instructor 2

Description: Supervised independent projects that may include laboratory work, assigned

readings, research papers, etc. Available in toxicology, biopharmaceutics, medicinal chemistry,

pharmacodynamics and pharmacokinetic.

Enrollment:

Campus: 1



PHA 327 Sterile and Non-Sterile

dosage forms

Required first year

pharmacy course

Instructor of

Record

3

Description: This course provides an introduction to different sterile and non-sterile dosage forms

and drug delivery systems. This course comprises of non-sterile dosage forms and drug delivery



delivery systems.

Enrollment:

Campus: 106

Distance: 73

Total: 179


Teaching Innovation: Course was reviewed and important aspects from United State

Pharmacopoeia were added to the content. Previously, they were provided as additional notes.

Additional calculations based problems (both in class and through Echo-capture) were introduced.


PHA 322 Pharmacy Skills Lab II Required first year

pharmacy course

Instructor 1

Description: PSL II will introduce and reinforce specific skills that coordinate with second

semester pharmacy courses through knowledge-in-use activities in simulated pharmacy practice

situations. Selected practice fundamentals and processes, such as patient counseling, patient safety,

and pharmaceutical calculations, are reinforced throughout all six semesters of the PSL sequence.

Enrollment:

Campus: 106

Distance: 73

Total: 179


PHA 551 Research Advanced

Pharmacy Practice

Experience.

Pharmacy Students Instructor 5

Description: The Research Advanced Pharmacy Practice Experience (APPE) is an elective

rotation designed to provide students with experience in research design and development,

performance of experiments, data collection and analysis, the peer review process, and animal or

human research regulations.

Enrollment:

Campus: 1


PHA 555 Academic Advanced

Pharmacy Practice

Experience

Pharmacy Students Instructor

(Microscopic

applications)

5

Description: The Academic Advanced Pharmacy Practice Experience (APPE) is an elective

pharmacy rotation course which exposes students to the design and delivery of didactic content in

a variety of settings, examines the diversity of learning strategies, and introduces students to the

expectations for teaching, scholarship and service activities of faculty members.

Enrollment:

Campus: 1


2015-2016: Graduate


MPS 634 Pharmaceutical Dosage

Forms and Drug Delivery

Systems

Graduate first year

pharmacy course

Instructor of

Record

3

Description: Basic principles of pharmaceutical dosage forms and drug delivery systems are

taught with respect to formulating drugs for bioavailability enhancement and drug targeting.

Pertinent pharmaceutical examples that are discussed include: Oral, parenteral, transdermal,

aerosol, etc., with emphasis placed on their importance, formulation considerations and ongoing

research.

Enrollment:

Campus: 2

Teaching Innovation: First time the graduate level course was introduced on these topics. The

content emphasized the current pharmaceutical industry examples. Content available via

webinar/PowerPoint slides was utilized to enhance the learning of students. Recent literatures

from high impact factor journals were reviewed for the selected topics.




dosage forms

Required first year

pharmacy course

Instructor of

Record

3





delivery systems.

Enrollment:

Campus: 108

Distance: 72

Total: 180



pharmacy course

Instructor 1






Enrollment:

Campus: 108

Distance: 72

Total: 180

2014-2015: Graduate


MPS 799 Master’s Thesis Graduate Students Instructor of

Record

6




course will also emphasize on the development of nanoparticles and biopharmaceutical aspects of

delivery systems.

Enrollment:

Campus: 3


MPS 792 Pharmaceutical Sciences

Discussion Series

Graduate Students Instructor of

Record

2

Description: Graduate students in Pharmaceutical Sciences will learn how to read journal articles

for optimum retention, critically evaluate the data, and objectively determine the paper's

contribution to the over-all body of knowledge. In addition they will gain valuable presentation

and public speaking skills.

Enrollment:

Campus: 6



Research


Record

5

Description: Supervised independent research for motivated students to become involved in

ongoing original research projects of the pharmaceutical sciences faculty.


Enrollment:

Campus: 2



Research


Record

3



pharmacodynamics and pharmacokinetics.

Enrollment:

Campus: 1



Presentation Series


Record

2

Description: This course focuses on scientific communication of research material in various

situations. Students will read and understand journal articles for optimum retention, critically

evaluate the data, and objectively determine the paper's contribution to the over-all body of

knowledge. Emphasis is on presenting information/research data in an appropriate and effective

manner.

Course Name Course Name Course Name Course Name Course

Name

MPS 797 MPS 797 MPS 797 MPS 797 MPS 797

Description: Supervised original research

Enrollment:

Campus: 1




dosage forms

Required first year

pharmacy course

Instructor of

Record

3






delivery systems.

Enrollment:

Campus: 122

Distance: 73

Total: 195



pharmacy course

Instructor 1





Enrollment:

Campus: 122

Distance: 73

Total: 195

2013-2014: Graduate



Discussion Series


Record

2

Description: Graduate students in Pharmaceutical Sciences will learn how to read journal articles

for optimum retention, critically evaluate the data, and objectively determine the paper's

contribution to the over-all body of knowledge. In addition they will gain valuable presentation

and public speaking skills.

Enrollment:

Campus: 7

Course Name Course Name Course Name Course Name Course

Name

MPS 797 MPS 797 MPS 797 MPS 797 MPS 797

Description: Supervised original research


Enrollment:

Campus: 1



Research


Record

3




Enrollment:

Campus: 1



Research


Record

3

Description: Supervised independent research for motivated students to become involved in

ongoing original research projects of the pharmaceutical sciences faculty.

Enrollment:

Campus: 2




dosage forms

Required first year

pharmacy course

Instructor of

Record

3





delivery systems.

Enrollment:

Campus: 114

Distance: 68

Total: 182




pharmacy course

Instructor 1





Enrollment:

Campus: 114

Distance: 68

Total: 182


PHA 398 Developmental Biology

Research Elective

Pharmacy Student Instructor of

Record

2

Description: This course provides students with the opportunity to become involved in a research

experience in the areas of developmental biology, teratology and toxicology through the use of a

virtual laboratory.

Enrollment:

Campus: 1

2012-2013: Graduate



Research


Record

3




Enrollment:

Campus: 1


Y. Graduate and Honors Student Thesis

Year Faculty Role Student (Description/Research)

2016-Present Faculty Mentor Pranit Singh (Undergraduate Student):

Curcumin Formulations and Delivery

2016-Present Thesis Committee Chair Masters

in Pharmaceutical

Sciences

Ashwini Gumireddy: Combination Drug

Delivery Systems for Various Food

Supplements

2016-Present Thesis Committee Chair Masters

in Pharmaceutical

Sciences

Meghan Sheth: Polymeric Materials Based

on Ionic Interactions for the Delivery of

Poorly Soluble Drugs.

2016-Present Thesis Committee Member

Masters in Pharmaceutical

Sciences

Rishabh Tukra: Intranasal Delivery of

Curcumin in Various Delivery Matrices

and Brain Homogenate.

2016-Present Thesis Committee Member


Sciences

Pushkar Saralkar: Delivery of Curcumin

Resveratrol Nanoparticles in Sodium

Alginate Matrix

2012-2016 Thesis Committee Member PhD

in Pharmaceutical

Sciences (MCPHS)

Ravi Varanasi: Utilization of Eutectic

Properties of Either Lidocaine or

Tetracaine and a Topical Permeation

Ehancer in Topical Patch Development

2013-2015 Thesis Committee Chair Masters

in Pharmaceutical

Sciences

Fan Meng: Investigating Crystallization

Tendency, Miscibility and Molecular

Interactions of Drug-Polymer Systems for

the Development of Amorphous Solid

Dispersions

2013-2015 Thesis Committee Chair Masters

in Pharmaceutical

Sciences

Urvi Gala: Preparation, Characterization

and Dissolution Study for Curcumin-

Resveratrol-Cyclodextrin Amorphous

Ternary System

2012-2015 Thesis Committee Chair Pharm.

D-Masters in Pharmaceutical

Sciences

Anne Trivino: Drug-Polymer and Drug-

Lipid Miscibility for the Development of

Amorphous Solid Dispersions and Solid

Lipid Nanoparticles


2012-2014 Thesis Committee Member


Sciences

Niranjan Kathe: Synthesis and Holistic

Characterization of Amino Acid

Complexes of Physiological Metal Ions to

be Used as Ergogenic Aid



Sciences

Rajvi Wani: Production of Nanoparticles

Through A Modified Mini Spray Dryer B-

290 Using a Nano Nozzle



Sciences

Shantanu Chandratre: Multifunctional

Nanoparticles for Cancer Therapy



Sciences

Sneha Dhapare: Multifunctional

Nanoparticles Containing Hydrophobic

and Hydrophilic Drugs for Anticancer

Drug Delivery

2012-2013 Pharm D Research

Jonathan Bernick: In-silico Predictions for

the Determination of Physicochemical

Properties of Drugs.

Z. Service

Service to Creighton University

Year Committee Role

June 2016-June 2018 University Planning Committee Member (Elected)

2013-2015 Creighton Undergraduate Admission

Telephone Follow Up initiative

Faculty Caller

Service to the School of Pharmacy and Health Professions

Year Committee Role

2016-Present Inter Professional Education

(IPE) Strategic Plan Writing Group

Member

2016-Present Steering group leadership for curricular

revisions

Member

2015-Present Pharmacy Assessment Committee Co-Chair

2015-Present Pharmacy Curriculum Committee Member (ex officio)

2014- Present MS in Pharmaceutical Sciences Admission

Committee Member


2014-2015 Pharmacy Admission Committee Member

2013-2015 Pharmacy Award Committee Member

2012-2014 Pharmacy Curriculum Committee Member

Service to the Department of Pharmacy Sciences

Year Committee Role

2012- Present Faculty Advisor Pharmacy Students

2014-Present Faculty Liaison Pharmacy Class of 2017

2014-Present Faculty representative (To showcase

department research/scholarly work to

undergraduate students)

Creighton Undergraduate

Research and Scholarship

day

2016 Faculty representative (To showcase

department research/scholarly work) St. Albert’s Research Day

2013-2015 Faculty Interviewer Pharmacy Students

Service to the Professions

Year Organization Role

2016-Present American Chemical Society, Omaha Section Chair-Elect

2015-Present Active Pharmaceutical Ingredients (API)

Focus Group, AAPS

Steering Committee

Member

2015-Present Targeted Drug Delivery Focus Group,

AAPS

Steering Committee

Member

2015-2016 American Chemical Society, Omaha Section Secretary

2014-Present Journal of Pharmaceutical Investigation Editorial Board Member

2014-Present American Pharmaceutics Review Editorial Board Member

2014-Present Assay and Drug Development Technologies Editorial Board Member

2014- Present Molecular Pharmaceutics Reviewer

2013-Present CPhI Pharma Awards Judge

2013-Present Midwest Student Biomedical Research

Forum

Judge

2012-Present European Journal of Pharmaceutical

Sciences

Reviewer

2012-Present Drug Development and Industrial Pharmacy Reviewer


2011-Present AAPS Creighton University student chapter Faculty Advisor

2009-Present AAPS Annual Meeting Abstract Reviewer

Service to the Community

Year Committee/Organization Role

2016-Present Indian Association of Nebraska Volunteer

2016-Present Hindu Temple, Omaha Volunteer

2015-Present Metro Science and Engineering Fair Volunteer

2015-Present Elkhorn Public Schools Volunteer

2005-Present Raising funds and awareness for girl child

education in India

Volunteer

1997-2005 Diabetes awareness group Volunteer

Documents

CURRICULUM VITAE - Creighton University and Tenure...Page 3 of 33 Curriculum Vitae - Chauhan 2012 Summer Initiative for Teaching Excellence in the Health Sciences (SITE), Creighton