Collagen Solutions Company Overview

We develop, manufacture and supply medical grade collagen biomaterials for use in research, medical devices, and regenerative medicine.

About Collagen Solutions

- Founded January 2014 and listedon the London Stock Exchange

- Global company with offices in the UK, Korea, New Zealand, and USA

- Fast-growing company with a diverse, stable customer base

- Innovation with internal developmentand acquired intellectual property

Significant Events

Merger of Collagen Solutions LLC (USA) and Collbio Limited (UK)

to create Collagen Solutions Plc

Acquisition of Southern Lights Biomaterials expands offering

to tissue and other formulations

Multiple customer contracts for research supply and orthopaedic,

wound-care, neurology, dental and cardiovascular surgery

Acquisition of Chondromimetic assets adds pipeline of regenerative

orthopaedic devices

January 2014

December 2014

2014-2015

September 2015

Global Operations

Delivering Value

Working Together

Scientific expertise and a collaborative approach:

• Faster time to market• Improved production• Superior products

World Class Standards

GMP, EDQM, ISO 13485 & 22442, materials sourced from BSE-free countries:

• Regulatory approvals• Quality and consistency• Safe, reliable supply

Broad Range of Materials

A comprehensive range of collagen biomaterials and forms: • Tissues• Powders• Coatings• Sponges• Membranes• Scaffolds

Working Together

FDA-Cleared Diabetic Ulcer TreatmentDevelopment and Manufacture of 510(k) Medical Device

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Autologous Cell Therapy Scaffold for Burn TreatmentUtilised customer IP and COS material and know-how to optimise and manufacture the scaffold product – FDA IND approved

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FDA-Cleared Bone GraftsCollagen gel and powder supply

World-Class Standards

- ISO 13485 (CFR 21 Part 820)- ISO 22442 (PI, II, III)- EDQM Certificates

• Australia• New Zealand

- cGMP B and C cleanrooms- Viral inactivation validation- Produced FDA approved device- Regulatory support packages

Broad Range of Materials

• Acid-solubilized • Pepsin-solubilized • Fibrillar • Gels • Powder • Sheet • Sponges• Matrices • Custom as required

Medical Grade Collagen

Pericardium• Minimally processed or

crosslinked or decellularized• Multiple thicknesses and

physical properties• Frozen or fresh packaging

Other• Bone• Tendon• Veins and Blood Vessels

Pericardium and Other Tissues

Summary

50+ years management experience in collagen

Global, diverse customer base

Supply chain control from source to device

Long-term technical partnering

Co-development and contract manufacturing

Turnkey offering decreases cost and time to

commercialization

Thank You