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Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Basics of Polysomnography
(PSG) Testing
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
The following presentation is being provided for informational and educational purposes only. While Compumedics endeavors to ensure the validity and accuracy of the information within, we cannot be held responsible for inaccuracies, opinions or practices that often vary between various experts or are without established acceptable medical standards. Please consult your own medical director for clarification or for policies that are specific to your facility.
We welcome your comments, suggestions and corrections. Please e-mail your comments to: [email protected]
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Why Perform Sleep Studies?
Quantify sleep pattern Determine cause of excess daytime sleepiness Initialize and evaluate treatment Evaluate treatment effectiveness
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Types of sleep studies Diagnostic - investigative study to determine if there are
identifiable problems with the patient’s sleep CPAP titration - once a patient is identified as having sleep
apnea, another study is performed in which the technician adjusts the CPAP/BiPAP level during the test and decides which mask and type of treatment is best
Split Night - combines a diagnostic study and a titration study into one night. The patient is diagnosed during the first half of the night; CPAP/BiPAP applied the second half if required by protocol
MSLT - Multiple Sleep Latency Test (nap study) MWT – Maintenance of Wakefulness Test
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Diagnostic Sleep Studies – Variables Evaluated
Sleep staging• Wake, NREM (N1,N2,N3), REM• Arousals
Respiratory• Apneas and hypopneas• Upper airway resistance
Limb EMG• PLMS• Restless legs
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Polysomnography (PSG)
EEG F4-M1, EEG C4-M1, EEG O2-M1, EOG-L(E1), EOG-R(E2), EMG (chin)
AIRFLOW, both Thermal and Nasal Pressure THOR EFFORT, ABDO EFFORT SpO2, ECG, LEG(L), LEG(R) SOUND, POSITION CPAP pressure and flow Optional: additional EEG, dB meters, temperature, blood pressure
Typical Montage
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Typical Polysomnogram
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Sleep Architecture
Normal? Deficient in REM? Contain supine REM? Deficient in Delta sleep? Fragmented or disrupted by frequent arousals?
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Normal Sleep Architecture Entered through NREM Approximately 90 minute cycle including NREM and
REM Slow wave dominates first third of night REM sleep dominates last third of night REM sleep: 20-25% total sleep time
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Examples - Sleep Hynograms
Normal Sleep Architecture
Normal Sleep Architecture
No Delta (Restorative) Sleep
No Delta (Restorative) Sleep
Severely Fragmented Sleep
Severely Fragmented Sleep
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Sleep Staging Variables Electroencephalogram (EEG) - acquired by surface
electrodes on the scalp at standardized locations (10-20 system)
Electrooculogram (EOG) - acquired by surface electrodes placed at the outer canthus of each eye
Electromyogram (EMG) - acquired by surface electrodes placed on the chin muscle (sub-mental)
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Sleep Staging Channels
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
EEG
Frequency and amplitude change with sleep stage:• Wake: high frequency• Stage N1 and REM: low amplitude, mixed frequency• Stage N2: spindles, K-complexes• Stage N3: delta waves (slow frequency, high amplitude)• Standard sleep epoch is 30 seconds (10 mm/sec paper
speed)
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
10-20 EEG Locations
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
EEG Electrode Placement
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Sleep Stage Criteria Awake
• Alpha or faster > 50% of epoch• Many eye movements• High EMG
Stage N1• Alpha or faster < 50 % of epoch• Increasing theta activity• Slow rolling eyes• Vertex waves
ALPHA WAVESALPHA WAVES
THETA WAVESTHETA WAVES
VERTEX WAVEVERTEX WAVE
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Sleep Staging Criteria Stage N2
Sleep spindles or K-complexes
Stage N3Delta-H > 20% of epoch
(≤ 2 Hz, ≥ 75uV)
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Sleep Staging Criteria REM
• Lowest EMG• Rapid Eye Movements
• Saw-tooth EEG• Low-amplitude, mixed
frequency EEG similar to stage 1
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
EOG EOG records voltage changes caused by eye movement EOG changes with sleep stage Wake: random, high amplitude
Stage 1: slow rolling
REM: very flat with occasional Rapid Eye Movements
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
EOG Electrode Placement
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
EMG Recorded as the potential between two surface
electrodes placed several centimeters apart Typically, the chin (submental) muscle is used
because it exhibits large differences during sleep, aiding in the identification of stages
Wake - high activity Sleep - lower activity REM sleep - paralysis of skeletal muscles
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
EMG Placement
Submental (chin) AASM placement =
one midline and two under the chin
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Wake
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Stage N1 Sleep
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Stage N2 Sleep
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Stage N3 Sleep
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Stage REM Sleep
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Respiratory variables Respiratory effort (thoracic and abdominal) Airflow (thermistor, thermocouple, nasal pressure,
ETCO2) SpO2 Snoring sounds Optional signals
• ETCO2• tcCO2
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Airflow Used for detecting respiratory events
• Apnea: no airflow• Hypopnea: reduced airflow
How is airflow commonly measured?• Temperature changes: thermistor/thermocouple – used
for apnea detection• In/ex pressure changes: nasal cannula – used for
hypopnea detection• ETCO2 – most often used in pediatrics
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Respiratory Effort
Used for classifying respiratory events
e.g. Apnea: no airflow but effort indicates obstruction Inductive plethysmography bands – AASM Piezo-electric bands EMG: diaphragm/intercostal Esophageal pressure
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Other Respiratory Variables
Gases: SpO2 – Blood oxygen level (%) by oximetry tcCO2 – Transcutaneous CO2 etCO2 – End Tidal CO2 Arterial CO2 – blood analysis
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Other Variables Typically Recorded
ECG Leg movement: EMG (AASM), piezoelectric Video Body position CPAP flow and pressure (DC input)
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Respiratory Events Apneas
• Obstructive• Central• Mixed
Hypopneas Respiratory Event Related Arousals - RERA
• Respiratory event does not meet the criteria for event types above
• Causes a disruption of the sleep architecture (arousal)
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Obstructive Apnea
Cessation of airflow for more than 10 seconds
With abdominal and/or thoracic effort Usually terminated by an arousal and/or
associated with a desaturation
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Example - Obstructive Apnea
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Central Apnea
Cessation of airflow, usually for more than 10 seconds
Without abdominal and/or thoracic effort May be terminated by an arousal and/or
associated with a desaturation Very different type syndrome than OSA; chemo-
receptor irregularities
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Example - Central Apnea
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Mixed Apnea Cessation of airflow >10 s (in adults) with
respiratory effort Contains both central and obstructive
components, with each component lasting at least one normal respiratory cycle
Typically leads to a desaturation and an arousal
Is really just a type of obstructive event with the same consequences
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Example - Mixed Apnea
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Hypopnea
Nasal Pressure signal amplitude drop by ≥ 30%
Duration of at least 10 seconds ≥ 4 % desaturation 90% of event meets amplitude reduction
criteria
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Hypopnea - Alternative
Nasal Pressure signal amplitude drop by ≥ 50%
Duration of at least 10 seconds ≥ 3 % desaturation or an associated arousal 90% of event meets amplitude reduction
criteria
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Example - Hypopnea
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
PLMS
Repetitive (at least 4) episodes of muscle contraction (0.5-10 s duration)
Minimum amplitude increase of 8 uV above baseline Separated by > 5 seconds, but not more than 90
seconds Arousals sometimes associated with the movements Positive diagnosis if more than 5 per hour of sleep Movements may be clinically significant only if
associated with arousals
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Example - PLMS
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Arousals
Abrupt shift of EEG frequency Lasts at least 3 seconds At least 10 seconds of prior stable sleep During REM requires concurrent increase in
chin EMG lasting at least one second
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Example – REM Arousal
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
ECG
Normal sinus rhythm? Bradycardia or Tachycardia? Frequent atrial/ventricular arrhythmias?
Run of 5 or more ventricular arrhythmias?
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
ECG – AASM Reporting Average heart rate during sleep Highest HR during recording/sleep Bradycardia < 40 bpm (lowest observed) Sinus Tachycardia > 90 bpm (highest observed) Narrow Complex Tachycardia (highest observed) Wide complex Tachycardia (highest observed) Asystole, longest pause Atrial fibrillation List other arrhythmias
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Basic Steps to Analyze a Study Using Compumedics Software
1. Automatic Analysis– Sleep Staging – Arousal Scoring– Respiratory Scoring– PLM Scoring
2. Manual Editing– Validate Sleep Staging– Event Editing: Respiratory, PLM, and ECG– Arousal Classification and editing
3. Reporting4. Archiving
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Sleep architecture
• What was the sleep efficiency?• What was the percent of each stage of
sleep?• What was the sleep onset time?• What was the REM onset time?
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Respiratory Events Which events were most common? Were there any obstructive events? What was the AHI (Apnea/Hypopnea Index)? What was the RDI (Respiratory Disturbance
Index) Apnea + Hypopnea + RERA per hour of sleep
What was the nadir and baseline SpO2? Was any snoring recorded?
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Leg Movements
Were they periodic? What was the index (number per hour of
sleep) Did they cause arousals?
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Arousals
How many per hour? Related to events??
• Respiratory events• Leg movements• Esophageal reflux• Seizures• Unknown (spontaneous)
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
CPAP/BiPAP
Effective? Best pressure? Best mask? Tolerance?
Copyright Compumedics Ltd.Basics of Polysomnography (PSG) Testing /09
Generate report Write results summary Save Print Print raw data examples Add doctors summary File and send to referring
doctors
Reporting Sleep Studies