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CONTRIBUTORS
Abramovici Armand - Department of Pathology, Saclder Medical School, University of Tel Aviv, Tel Aviv, Israel
Acker Helmut - Max-Planck-Institut fUr Systemphysiologie, Dortmund 1, F.R.G.
Albrecht J. - Department of Neuropathology, Polish Academy of Sciences Medical Research Center, Warsaw, Poland
Alexander A. - Department of Biology, McMaster University, Hamilton, Ontario, Canada
Almaraz Laura - Departamento de Fisiologfa y Bioqufmica, Facultad de Medicina, Universidad de Valladolid, Valladolid, Spain
Bairam Aida - Laboratoire de Physiologie, Faculte de Medecine, Unite INSERM 272, Universite de Nancy I, Nancy, France
Bartels Else Marie - University Laboratory of Physiology, Oxford University, Oxford, U.K.
Bee Denise - Department of Experimental Medicine, University of Sheffield Medical School, Sheffield, U.K.
Behm Reinhard - Department of Physiology, University of Rostock, Rostock, F.R.G.
Biondelli Vincenzo - Institute of Physiological Sciences, School of Medicine, "G. D' Annunzio" University, Chieti, Italy
Bisgard Gerald E. - Department of Comparative Biosciences. School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin. U.S.A.
Bolling Brigitte - Max-Plank-Institut fUr Systemphysiologie, Dortmund I, F.R.G.
Borghini N. - URA CNRS 1195, Faculte de Medecine Grange-Blanche, Lyon, France
Bradford Aidan J. - Department of Physiology, Royal College of Surgeons in Ireland, Dublin 2, Ireland
Buckler Keith James - University Laboratory of Physiology, Oxford, U.K.
Carroll John Lee -Johns Hopkins Hospital, Pediatric Pulmonology, Baltimore, Maryland, U.S.A.
Cerretelli Paolo -Department of Physiology , University of Geneva, Geneva, Switzerland
441
Chen J. - Department of Physiology, University of Utah School of Medicine, Salt Lake City, Utah, U.S.A.
Chemiack Neil S. -Department of Medicine, Case Wastem Reserve University, Cleveland, Ohio, U.S.A.
Clarke J.A. - Department of Anatomy, Queen Mary and Westfield College, London, U.K.
Costa M. - IT.B.A., C.N.R, Milano, Italy
Cottet-Emard J.M. - URA CNRS 1195, Faculte de Medecine, Grange- Blanche, Lyon, France
Cragg Patricia Ann - Department of Physiology, University of Otago Medical School, Dunedin, New Zealand
Crance Jean-Pierre -Laboratoire de Physiologie, Faculte de Medecine, Unite INSERM 272, Universite de Nancy I, Nancy, France
Cutz E. - Hospital For Sick Children, Toronto, Ontario, Canada
Dagerlind A. - Department of Histology and Neurobiology, Karolinska Institute, Stockholm, Sweden
Dalmaz Yvette - Departement de Physiologie, Faculte de Medecine Grange-Blanche, Lyon, France
Daly Michael de Burgh - Department of Physiology, Royal Free Hospital School of Medicine, London, U.K.
Dashwood Michael - Department of Physiology, Royal Free Hospital School of Medicine, London, U.K.
Data Pier Giorgio - Institute of Physiological Sciences, School of Medicine, "G.D' Annunzio" University, Chieti, Italy
Delpiano Marco Antonio - Max-Planck-Institut fUr Systemphysiologie, Dortmund, F.RG.
de Muinck Keizer W. H. - Department of Pharmacology and German Institute for High Blood Pressure Research, Ruprecht-Karls University, Heidelberg, F.RG.
Di Giulio Camillo - Institute of Physiological Sciences, School of Medicine, "G.D' Annunzio" University, Chieti, Italy
Di Tano Guglielmo - Institute of Physiological Sciences, School of Medicine,"G D'Annunzio" University, Chieti, Italy
442
Dinger Bruce G. - Department of Physiology, University of Utah School of Medicine, Salt Lake City, Utah, U.S.A.
Dufau Evelyne - Max-Plank-Institut fUr Systemphysiologie, Dortmund 1, F.R.G.
Ead Harold William - Department of Physiology, Royal Free Hospital, London, U.K.
Edelman Norman H. -Department of Medicine, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, New Jersey, U.S.A.
Evrard Y. - Institut de Recherchers Internationales Servier, Paris, France
Eyzaguirre Carlos -Department of Physiology, University of Utah School of Medicine, Salt Lake City, Utah, U.S.A.
Fadic R. - Laboratory of Neurobiology, Catholic University of Chile, Santiago 1, Chile
Feely S. - Department of Physiology and Histology, University College, Dublin 2, Ireland
Ferretti G. - Department of Physiology, University of Geneva, Geneva, Switzerland
Fidone Salvatore J. -Department of Physiology , University of Utah School of Medicine, Salt Lake City, Utah, U.S.A.
Finley James C.W. - Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, U.S.A.
Fitzgerald Robert S. - Department of Environmental Health Sciences, Johns Hopkins Medical Institutions, Baltimore, Maryland, U.S.A.
Forster II Robert E. - Department of Physiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, U.S.A.
Franz U. - Department of Physiology, University of Rostock, Rostock, F.R.G.
Garcia-Sancho J. - Departamento de Bioquimica y Fisiolo gia, Facultad de Medicina, Universidad de Valladolid, Valladolid, Spain
Gigante Gabriele - Institute of Physiological Sciences, School of Medicine, "G. D'Annunzio" University, Chieti, Italy
Giles S. -Department of Physiology and Histology, University College, Dublin 2, Ireland
Gomez·Nino A. - Departamento de Bioqufmica y Fisiologia, Facultad de Medicina, Universidad de Valladolid, Valladolid, Spain
443
Gonzalez C. - Departamento de Bioqu{mica y Fisiolog{a. Facultad de Medicina. Universidad de Valladolid. Valladolid. Spain
Gorlach Agnes - Max-Plank-Institut fur Systemphysiologie. Dortmund 1. F.R.G.
Grassi Bruno - I.T.B.A.. C.N.R.. Milano. Italy
Habeck Jorg-Olaf - Department of Pathology. Kuchwald Hospital, Chemnitz, F.R.G.
Hannhart Bernard - Laboratory of Respiration Physiopathology. INSERM U-14. Vandoeuvre-Ie-Nancy. France
Hanson G. - Department of Physiology. University of Utah School of Medicine. Salt Lake City. Utah. U.S.A.
Haouzi P. - Laboratoire de Physiologie. Faculte de Medecine. Unite INSERM 272. Universite de Nancy I. Nancy. France
He L. - Department of Physiology. University of Utah School of Medicine. Salt Lake City. Utah. U.S.A.
Hertzberg T. - Department of Pediatrics. Karolinska Institute. Stockholm, Sweden
Hokfelt T. -Department of Histology and Neurobiology. Karolinskalnstitute. Stockholm. Sweden
Holgert Hans - Department of Pediatrics. Karolinska Institute. Stockholm. Sweden
Holtermann Georg - Max-Plank-Instutut fiir Systemphysiologie. Dortmund 1. F.R.G.
Honda Yoshiyuki - Department of Physiology. School of Medicine. Chiba University, Chiba Inohana. Japan
Huang W-X -Department of Physiology. School of Medicine. University of Pennsylvania. Philadelphia. Pennsylvania. U.S.A.
Iezzi Manuela -Institute of Physiological Sciences. School of Medicine. "G. D' Annunzio" University. Chieti. Italy
Iturriaga Rodrigo -Laboratory of Neurobiology • Catholic University of Chile. Santiago. Chile
Katz David M. - Department of Neurosciences, Case Western Reserve University School of Medicine. Cleveland. Ohio. U.S.A.
Kennedy M. - Department of Physiology and Histology. University College. Dublin 2. Ireland
444
Kolsicka I. - Department of Neuropathology, Polish Academy of Sciences Medical Research Center, Warsaw, Poland
Kondo Hisatake - Department of Anatomy, School of Medicine, Kanazawa University, Kanazawa, Japan
Kou Yu-Ru - Department of Medicine, Case Western Reserve University, Cleveland, Ohio, U.S.A.
Koyano Hayao - Department of Physiology, Akita University School of Medicine, Akita, Japan
Kummer Wolfgang - Institute of Anatomy and Cell Biology, University of Heidelberg, Heidelberg, F.R.O.
Lagadic-Gossmann D. - University Laboratory of Physiology, Oxford, England
Lagercrantz Hugo -Department of Pediatrics, Karolinska Institute, Stockholm, Sweden
Lahiri Sukamhai - Department of Physiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, U.S.A.
Larrain C. -Laboratory of Neurobiology ,Catholic University of Chile, Santiago 1, Chile
Leitner Louis-Michel - Laboratoire de Physiologie, Faculre de Mooecine, Toulose, France
L6pez-L6pez Jose Ramon - Departamento de Bioquimica y Fisiologia, Facultad de Medicina, Universidad de Valladolid, Valladolid, Spain
Loyola H. -Laboratory of Neurobiology, Catholic University of Chile, Santiago 1, Chile
Marchal Francois - Laboratoire de Physiologie, Faculte de Mooecine, Unite INSERM 272, Universite de Nancy I, Nancy, France
Marconi C. - I.T.B.A., C.N.R., Milano, Italy
McKeogh Donogh - Department of Physiology and Histology, University College, Dublin 2, Ireland
McLaren A. J. - University Laboratory of Physiology, Oxford University, Oxford, U.K.
McQueen Daniel - Department of Pharmacology, University of Edinburgh Medical School, Edinburgh, Scotland, U.K.
Melton Joseph E. - Department of Medicine, University of New Jersey, R W J Medical School, New Brunswick, New Jersey, U.S.A.
445
Mewes H. - Department of Physiology, University of Rostock, Rostock, F.R.G.
Meyer M. - Max-Plank-Institute fiir Experimental Medicine, Gottingen, F.R.G.
Mitchell G. -Department of Comparative Biosciences, University of Wisconsin, Madison, Wisconsin, U.S.A.
Mokashi A. -Department of Physiology, School of Medicine , University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.
Morelli Luca -Institute of Physiological Sciences, School of Medicine, "G.D' Annunzio" University, Chieti, Italy
Muddle J.R. - Neurological Sciences, Royal Free Hospital School of Medicine, London, U.K.
Neubauer Judith - Department of Medicine, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, New Jersey, U.S.A.
Newman Charlotte -Department of Pathology , University of Toronto, Toronto, Ontario, Canada
Niu W. - Department of Comparative Biosciences, University of Wisconsin, Madison, Wisconsin, U.S.A.
Nolan Pilip - Department of Physiology and Histology, University College, Dublin 2, Ireland
Nurse Colin -Department of Biology, McMaster University, Hamilton, Ontario, Canada
Nye Piers C.G. - University Laboratory of Physiology, Oxford University, Oxford, U.K.
O'Regan Ronan -Department of Physiology and Histology, University College, Dublin 2, Ireland
ObesoAnn -Departamento de Fisiologia y Bioqufrnica, Facultadde Medicina, Universidad de Valladolid, Valladolid, Spain
Pallot David - Department of Anatomy, University of Leicester Medical School, Leicester, U.K.
Paterson David J. - University Laboratory of Physiology, Oxford University, Oxford, U.K.
Peers Christopher- Department of Pharmacology, Worsley Medical and Dental Building, University of Leeds, Leeds, UK
446
Pequignot Jean-Marc - Laboratoire de Physiologie, Faculte de Medecine GrangeBlanche, Lyon, France
Perez-Garda M.T. - Departamento de Bioquimica y Fisiologia, Facultad de Medicina, Universidad de Valladolid, Valladolid, Spain
Peyrin L. - URA CNRS 1195, Faculte de Medecine Grange-Blanche, Lyon, France
Pizarro J. -Department of Comparative Biosciences, University of Wisconsin, Madison, Wisconsin, U.S.A.
Pokorski Miecz:yslaw -Department of Physiology , Polish Academy of Sciences Medical Research Center, Warsaw, Poland
Polak Joseph - Department of Neurosciences, Case Western University School of Medicine, Cleveland, Ohio, U.S.A.
Prabhakar Nanduri R. - Department of Medicine, Case Western Reserve University, Cleveland, Ohio, U.S.A.
Ramirez B. - Laboratory of Neurobiology, Catholic University of Chile, Santiago I, Chile
Rettig R. - Department of Pharmacology and German Institute for High Blood Pressure Research. Ruprecht-Kals University. Heidelberg. F.R.G.
Rocher A. -Departamento de Bioquimica y Fisiologia, Facultadde Medicina. U niversidad de Valladolid, Valladolid, Spain
Rumsey William L. - Department of Radiopharmaceuticals, Bristol-Myers Squibb, Pharmaceutical Research Institute, New Brunswick, New Jersey, U.S.A.
Sato Minoru - Department of Physiology. Akita University School of Medicine, Akita, Japan
Schamel Abdenbi - Laboratoire de Cytologie, Universite de Bordeaux II, Talence, France
Schena F. - Department of Physiology, University of Geneva, Geneva, Switzerland
Shirahata Machiko - Department of Environmental Health Sciences, Johns Hopkins Medical Institutions, Baltimore, Maryland, U.S.A.
Soulier V. - URA 1195 CNRS, Faculte de M6decine Grange-Blanche, Lyon, France
Spergel Daniel - Department of Physiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, U.S.A.
447
Spyer K.M. - Department of Physiology, Royal Free Hospital School of Medicine, London, U.K.
Stea Anthony - Department of Biology, McMaster University, Hamilton, Ontario, Canada
Stensaas LJ. - Department of Physiology, University of Utah School of Medicine, Salt Lake City, Utah, USA
Strosznajder R. -Department of Neurophysiology ,Polish Academy of Sciences Medical Research Center, Warsaw, Poland
Sykes R.M. - Department of Physiology, Royal Free Hospital School of Medicine, London, U.K.
Tanaka Michiko - Department of Physiology, School of Medicine, Chiba University, Chiba, Japan
Torrance Robert William - University Laboratory of Physiology, St. John's College, Oxford, U.K.
Unger Th. -Department of Pharmacology and German Institute for High Blood Pressure Research, Ruprecht-Karls University, Heidelberg, F.R.G.
Vaughan-Jones Richard David - University Laboratory of Physiology, Oxford, U.K.
Verna Alain - Laboratoire de Cytologie, Universire de Bordeaux II, Talence, France
Vollmer C. - Department of Biology, McMaster University, Halmilton, Ontario, Canada
Vouillarmet A. - URA CNRS 1195, Faculte de Medecine Grange-Blanche, Lyon, France
Wang D. - Research Institute, University of Toronto, Toronto, Ontario, Canada
Wang W.-J. - Department of Physiology, University of Utah School of Medicine, Salt Lake City, Utah, U.S.A.
Wang Z.-Z. - Department of Physiology, University of Utah School of Medicine, Salt Lake City, Utah, U.S.A.
Warner M. - Department of Comparative Biosciences, University of Wisconsin, Madison, Wisconsin, U.S.A.
Wilson David F. - Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, U.S.A.
Xi L. - Department of Physiology, University of Geneva, Geneva, Switzerland
448
Yamamoto Miyuki -Department of Anatomy, School of Medicine, Tohoku University, Sendai, Japan
Yoshizaki Katsuaki -Department of Physiology, Akita University School of Medicine, Akita, Japan
Zapata Patricio - Laboratory of Neurobiology, Catholic University of Chile, Santiago 1, Chile
449
INDEX
Al cell group, 431 A2 cell group, 431 A5 cell group, 432 Acetylcholine, 123, 131 Acid and isohydric hypercapnia, 172 Acid hypothesis, 177,180 Acidic transduction, 154 Adaptation of response affected by 02' 243,
244 Adenosine, 289,290,292 Adrena1s glands, 10 Adrenergic receptors, 305 Afferent, 326 Airway, 326 Almitrine, 22, 56
bismesylate, 51,315,319 Alpha-2 adrenoreceptors, 301· Alpha-2 agonist, 303 Anion exchangers, 177, 180,181 ANP
immunoreactivity, 272 receptors, 275 release, 274
Apnea, 384 Aromatic-L-amino-acid-decarboxylase, 67,
68,70 ATP,224 Autoradiography, 93 Autoreceptors, 88
Bicarbonate hypothesis, 241 Blunted hypoxic drive, 269 Body temperature, 371 Brain stem, 429 Breath-hold divers, 354 British School, 131 Buffering PC02 changes, 145 Butyrate, 213
Ca2+-activated, 180 Ca2+ -dependent K+ current, 422 Calcitonin gene-related peptide, 67, 68, 70,
274 Calcium, 117,124
channels, 151,153 Capillary lumen, 237 Capsaicin, 266 Carbon dioxide, 213,323 Carbonic anhydrase, 171, 237
ofCB disequilibrium pH, 245 inhibition, 245, 246 steady responses, 245,246 transient responses, 244, 245,246
Cardiac inhibition, 333
lung inflation, 334 central modulation, 335
output, 327, 360 Carotid body, 17,18,117,191,213,435
denervation, 309 in vivo/in vitro, 302 resection, 359,360 hypoxic blunting, 246,247 maturation, 246,247
Carotid neurotomy, 372 sinus nerve, 12, 345
Cat, 365 Catalytic reaction, 142 Catecholamines, 165,259,394
release, 150, 152, 281, 282 turnover, 10
Cell culture, 47, 81, 228 Cell-free perfusion, 51 Central modulation, 335 Central norepinephrine, 429 Chemodenervation, 430 Chemoreceptor, 3,213,381
tcrmoregulation, 378 afferents, 43
Chemoreflexogenic ventilatory drive, 353 Chemosensitivity, 397, 408 Chemosensory
discharge, 374,416 drive, 376 response, 222
to hypoxia, 417 transmission, 435
Chemostatic, 377 Chemotransduction, 118, 194,213 Chloride, 125
ions, 178, 180 Cholinergic
blockers, 133 hypothesis, 131
Chronic hypoxia, 80,95,96,401 Chronic hypoxiemia, 32,37 Chronic study, 56 cr / HC03'-exchanger, 106, 175 Climbers, 353 Close arterial injection-method, 235 CNS, 345
activity, 388 inhibition, 272, 273
CO2
hydration, 174 response, 407
451
CO2 (cont'd) response curves. 388 transport. 144
CO2-II' chemoreception. 177.180 CO2-HC03'. 177.178,180 CO2-02 stimulus
interaction, 177. 181 threshold, 180
Cobalt. 117, 40 I Confocal scanning optical microscope, 159 Constant flow. 57 Constant pressure. 53 Constant volume, 53 Convergence of stimuli, 241 Cyanide pulse, 435 Cyclic AMP 279,280,282,284
content 26, 27 Cyclic GMP immunoreactivity. 27.28 Cytocrome b. 160 Cytosolic calcium, 206. 207
D2 RmRNA,85 Decentralization, 396 Dehydration reaction velocity. 141 Denervation. 126 Development, 47 Dexamethasone, 96 Diaphragmatic EMG. 375 Dihydropyridines, 152 Diuresis. 318 Divalent cations. 120 DNA Synthesis. 82 OOPAC, 185 Dopamine, 44, 123. 166, 181,280,282,283,
296. 436 b-hidroxylase. 67. 68, 70. 95 metabolism. 183. 185. 186. 187 release. 437 turnover. 395
Dopaminergic D2 receptors. 297 Dopaminergic receptors. 27 Down regulation. 305 Doxapram. 382.421 Dynamic response
to hypoxia. 417 to CO2 response, 410
Efferent inhibition. 45 Electrophoresis, 402 Enderson-Hasselbalch reaction. 138 Endothelin. 17 Enzyme mechanism, 141 Erythropoietin. 161 Esterase. 139 Exercise, 259,327 Extracellular
hypothesis, 243 pH, 207.251
452
Extracellular pH (cont'd) heightening, 207 lowering, 206
Fetus. 415,418 Fluorescence. 200 Function of CA. 143 Fura-2. 153
Genetics, 140 Genioglossus, 323 Glands
adrenals. 10 submaxillary, 10
Glomerular filtration rate, 318 Glomus cell, 79,87.177.180.181.227 Glucose, 221
consumption, 120 uptake, 111
Glutamate. 221 Glycolysis, 117 GSH/GSSG, 161 Guanabenz, 303 Guanethidine. 396
3H-norepinephrine, 93 II' transport, 144 ~02 formation. 158 Haloperidol, 295 HCO'3 as substrate, 145 Headache receptors. 237 Heart, 10 Heme proteins, 157 Hep G2 cells, 158 5lIT. 18
receptor, 22
Human carotid body. 31.37 Humans. 359 Hybridization, 86 Hydration reaction velocity. 137 Hypercapnia, 183.201.296.353 Hyperoxic tests: Diaphragmatic EMG, 375 Hyperthermia, 373 Hypertrophy CB, 31 Hyperventilation carotid neurotomy. 372 Hypocapnia. 328, 329 Hypothesis
acid. 177,180 bicarbonate. 241 cholinergic. 131 extracellular, 243 intracellular. 243
Hypoxia. 112, 113, 115, 169. 173. 183. 186. 187.194.197,200.213.259.267. 296,315.345,353,359.360
Hypoxic transduction. 150. 154 Hypoxic vasocostriction. 161
Image analysis, 3 Imaging oxygen pressure, 197 Immunocytochemistry, 94,395 Immunohistochemistry 32 Inflation reflex, 362, 363 In situ hybridization, 86 In vitro, 295 In vivo, 119 Indomethacin, 282, 284 Intracellular
calcium, 153, 154 hypothesis, 178, 243 pH, 103,112,113,178,181,197,198,
201,213,251 Ionic currents, 425 IP3, 120 Isoproterenol, 280,281,283,284 Isozymes, 140
K+
channel Ci+-activated, 180 02-sensitive, 180
conductance, 384 current, 422
Kittens, 387, 416
Larynx, 323 Lipid-derived second messengers, 194 Locus coeruleus, 432 Long term
normobaric hypoxia, 394 potentiation, 349 hypoxia, 9,430
Lung arterioles, 310 histology, 310 inflation, 334
Macroprotein pattern, 401 Mean mitochondrial volumes, 55 Mean numbers/area, 54 Mechanoreceptor, 324 Medullary chemoreceptors: Site of carbonic
anhydrase, 238 Met-enkephalin, 275 Metabolic
acidosis, 253 hypotesis, 181
Methazolamide, 171 Mitochondria, 52,54,57,58 Mitosis, 83 Monkey, 365
Na+-HC03" transporter, 120 Na+/glucose cotransporter, 120 Na+(H+ exchange, 106 Natriuresis, 318
Neonatal capsaicin, 268 Neonate, 166 Neuroendocrine
cells, 73 markers, 31
Neurofilament, 67, 68, 70 Neuronal markers, 31 Neuropeptide Y, 67,68,70 Neurotrasmitter, 131 Newborn, 381,390,407,418 NGFR,61 Nickel, 118 Nicotine, 222, 296 Nitrogen tests: Chemosensory discharge, 374 Noradrenaline, 183, 185, 186 Noradrenergic inhibition, 259 Norepinephrine, 259,260,301 Numbers/unit volume, 55
180 exchange method, 143 02 -C02 interaction, 411 02 -sensitive, 180 Optical measurements, 197 Oxygen
chemoreception, 177,180,197 tests, 367 effects on chemoreceptor adaptation, 245
Pancuronium, 266 Patch-clamp, 229,421 Perfusion, 213,224 Perineurium, 61 Peripheral chemoreceptors, 346 Petrosal ganglion, 43,88 pH, 125
extracellular, 206, 207, 251 intracellular, 103,112,113,178,181,197,
198,201,213,251 tissue, 119
Pharyngeal, 325 Phloretin, 115 Phlorizin, 115 Phosphoinositides, 191 Phospholipase C, 192 Phosphorescence, 198, 199 Photodiodearray spectrophotometer, 159 P02 sensor, 157 Polyacrylamide gel, 402 Postnatal development, 389 Potassium, 365 Prolonged hypoxia, 304 Prostaglandin, 280, 282, 284 Proteins, 401,405 Pulmonary, 73
artery pressure, 310 vasoconstriction, 311
Pyruvate, 113
453
Quantitative analysis, 53
Rat, 265 carotid body, 4
Receptor, 120,325 Reduced-Haloperidol, 298 Renal function, 315 Respiratory
acidosis, 253 afterdischarge, 347 chain, 160 control, 390 depression, 347 stimulants, 383
Second messenger lipid-derived, 194 systems, 279,287
Selective perfusion, 132 Sensor, 58 Serotonin, 73,280 SIF cells, 25, 26, 28, 393 Sinus nerve
activity, 408 transection, 396
Small cell lung carcinoma, 73 Sodium, 124
cyanide, 292, 296 SP- antagonist, 267 Spindle cell proliferation, 38 Spiroperidol, 13 Spontaneous hypertension, 5 Stereological analysis, 52, 56 Stimuli: Convergence of CO2 and °2 , 241 Stop-flow, 222 Structure human CB, 37 Submaxillary glands, 10 Substance P, 46,67,68,69,70, 132, 165,
168,265,280 Sulfonamide inhibitors, 142 Superfusion, 197,199 Superior cervical ganglion, 401 Swedish School, 131 Sympathetic
ganglia, 393 tissue, 9
Tachypnea: Hypertermia, 373 Taurine, 436,437 Thermoreceptors chemosensory drive, 376 Thermoregulation, 378 Thermosensors body temperature, 371 Thermostatic chemostatic, 377 Threshold, 180 Tissue pH, 119 Tonicity, 126 Trasmembrane carrier-mediated transport,
438
454
Turnover number, 141 Type I cell, 52,103,251,424 Tyrosine hydroxylase, 44,67,68,69,70, 166
Ultrastructure, 51, 57 Unmyelinated fibers, 269 Unstable respiratory control, 387 Unusual environments, 353 Urine flow, 318
Vascular compartment, 7 Vasoactive intestinal peptide, 68,70 Ventilation, 260, 261 Ventilatory
drive from arterial chemoreceptors, 368 parameters, 359,360 response, 289,290,327 response to hypoxia, 415
Video system, 198 Volume tractions, 54
Water/electrolyte balance, 271
